Functions and Diseases

RBP Type Non-canonical_RBPs
Diseases CancerSARS-COV-2
Drug N.A.
Main interacting RNAs N.A.
Moonlighting functions Metabolic enzyme
Localizations N.A.
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000092621 Gene ID 26227 Accession 8923
Symbol PHGDH Alias NLS;PDG;PGD;NLS1;PGAD;PGDH;SERA;3PGDH;3-PGDH;PHGDHD;HEL-S-113 Full Name phosphoglycerate dehydrogenase
Status Confidence Length 95808 bases Strand Plus strand
Position 1 : 119648411 - 119744218 RNA binding domain N.A.
Summary This gene encodes the enzyme which is involved in the early steps of L-serine synthesis in animal cells. L-serine is required for D-serine and other amino acid synthesis. The enzyme requires NAD/NADH as a cofactor and forms homotetramers for activity. Mutations in this gene have been found in a family with congenital microcephaly, psychomotor retardation and other symptoms. Multiple alternatively spliced transcript variants have been found, however the full-length nature of most are not known. [provided by RefSeq, Aug 2011]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
36147463 PHGDH Inhibits Ferroptosis and Promotes Malignant Progression by Upregulating SLC7A11 in Bladder Cancer. Liliang Shen 2022-01-01 International journal of biological sciences
30744688 Phosphoglycerate dehydrogenase promotes pancreatic cancer development by interacting with eIF4A1 and eIF4E. Xuhui Ma 2019-02-11 Journal of experimental & clinical cancer research : CR
34178629 PHGDH Is Upregulated at Translational Level and Implicated in Platin-Resistant in Ovarian Cancer Cells. Fangfang Bi 2021-01-01 Frontiers in oncology
32226297 The Role of D-3-Phosphoglycerate Dehydrogenase in Cancer. Xiaoya Zhao 2020-01-01 International journal of biological sciences

Transcripts

Name Transcript ID bp Protein Translation ID
PHGDH-223 ENST00000641597 2585 533aa ENSP00000493382
PHGDH-206 ENST00000493622 742 89aa ENSP00000493433
PHGDH-225 ENST00000641720 548 72aa ENSP00000492948
PHGDH-234 ENST00000642041 943 97aa ENSP00000493415
PHGDH-232 ENST00000641947 1774 526aa ENSP00000492994
PHGDH-211 ENST00000641213 2053 165aa ENSP00000493079
PHGDH-209 ENST00000641074 1780 429aa ENSP00000493446
PHGDH-207 ENST00000496756 508 No protein -
PHGDH-210 ENST00000641115 1638 445aa ENSP00000493264
PHGDH-233 ENST00000642021 2794 No protein -
PHGDH-218 ENST00000641491 986 165aa ENSP00000493187
PHGDH-202 ENST00000369409 1882 532aa ENSP00000358417
PHGDH-208 ENST00000641023 1866 533aa ENSP00000493175
PHGDH-219 ENST00000641513 735 165aa ENSP00000493398
PHGDH-221 ENST00000641573 1180 No protein -
PHGDH-222 ENST00000641587 566 63aa ENSP00000493453
PHGDH-220 ENST00000641570 1036 123aa ENSP00000493213
PHGDH-229 ENST00000641891 2175 165aa ENSP00000493288
PHGDH-216 ENST00000641375 2196 165aa ENSP00000493089
PHGDH-203 ENST00000462324 767 No protein -
PHGDH-215 ENST00000641371 725 145aa ENSP00000493305
PHGDH-213 ENST00000641272 758 239aa ENSP00000493432
PHGDH-212 ENST00000641247 710 97aa ENSP00000492955
PHGDH-226 ENST00000641756 2132 70aa ENSP00000493147
PHGDH-224 ENST00000641711 712 No protein -
PHGDH-230 ENST00000641927 1678 No protein -
PHGDH-214 ENST00000641314 1558 No protein -
PHGDH-201 ENST00000369407 3180 No protein -
PHGDH-227 ENST00000641811 1031 276aa ENSP00000493296
PHGDH-228 ENST00000641847 692 No protein -
PHGDH-217 ENST00000641455 312 No protein -
PHGDH-204 ENST00000469443 653 No protein -
PHGDH-231 ENST00000641939 540 No protein -
PHGDH-205 ENST00000482968 1754 No protein -

Gene Model

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
26161Vascular Diseases1.4600000E-005-
33861Glomerular Filtration Rate3.0081764E-005-
60721Metabolism3E-1421886157
85047Macular Degeneration2E-1428250457
86221Amino Acids3E-2126068415
86222Metabolism3E-2126068415
101044Insulin Resistance2E-1423378610
101426Body Height2E-925282103

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000092621homo_sapiensENSP0000031343249.390228.3537homo_sapiensENSP0000049317530.39417.4484
ENSG00000092621homo_sapiensENSP0000037241143.822825.8741homo_sapiensENSP0000049317535.27220.8255
ENSG00000092621homo_sapiensENSP0000031182520.507612.2843homo_sapiensENSP0000049317537.898722.7017

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000092621homo_sapiensENSP0000049317599.624899.6248nomascus_leucogenysENSNLEP0000000659594.148994.1489
ENSG00000092621homo_sapiensENSP0000049317510099.8124pan_paniscusENSPPAP0000003499593.019292.8447
ENSG00000092621homo_sapiensENSP0000049317599.812499.8124pongo_abeliiENSPPYP0000000112099.812499.8124
ENSG00000092621homo_sapiensENSP0000049317510099.8124pan_troglodytesENSPTRP0000000201393.019292.8447
ENSG00000092621homo_sapiensENSP0000049317510099.2495gorilla_gorillaENSGGOP0000004113691.896691.2069
ENSG00000092621homo_sapiensENSP0000049317590.243982.7392ornithorhynchus_anatinusENSOANP0000002457180.033373.3777
ENSG00000092621homo_sapiensENSP0000049317594.371586.8668sarcophilus_harrisiiENSSHAP0000001785394.371586.8668
ENSG00000092621homo_sapiensENSP0000049317594.183985.5535notamacropus_eugeniiENSMEUP0000001348894.183985.5535
ENSG00000092621homo_sapiensENSP0000049317566.979464.728choloepus_hoffmanniENSCHOP0000000139773.30670.8419
ENSG00000092621homo_sapiensENSP0000049317571.857461.3508dasypus_novemcinctusENSDNOP0000002765276.753565.5311
ENSG00000092621homo_sapiensENSP0000049317586.491684.2402erinaceus_europaeusENSEEUP0000001116086.491684.2402
ENSG00000092621homo_sapiensENSP0000049317556.097653.4709echinops_telfairiENSETEP0000000436661.776958.8843
ENSG00000092621homo_sapiensENSP0000049317597.56196.4353callithrix_jacchusENSCJAP0000006352192.691691.6221
ENSG00000092621homo_sapiensENSP0000049317598.499197.3734callithrix_jacchusENSCJAP0000003704098.499197.3734
ENSG00000092621homo_sapiensENSP0000049317596.998196.4353cercocebus_atysENSCATP0000002989394.862494.3119
ENSG00000092621homo_sapiensENSP0000049317591.18289.8687macaca_fascicularisENSMFAP0000001849385.41384.1828
ENSG00000092621homo_sapiensENSP0000049317599.249598.8743macaca_mulattaENSMMUP0000003927896.532896.1679
ENSG00000092621homo_sapiensENSP0000049317599.437199.0619macaca_nemestrinaENSMNEP0000003141696.188895.8258
ENSG00000092621homo_sapiensENSP0000049317594.183992.8705papio_anubisENSPANP0000004414785.665584.471
ENSG00000092621homo_sapiensENSP0000049317597.185796.6229mandrillus_leucophaeusENSMLEP0000003078995.045994.4954
ENSG00000092621homo_sapiensENSP0000049317588.930686.3039tursiops_truncatusENSTTRP0000000915288.930686.3039
ENSG00000092621homo_sapiensENSP0000049317525.703624.5779mus_spretusMGP_SPRETEiJ_P006183992.567688.5135
ENSG00000092621homo_sapiensENSP0000049317596.0693.4334equus_asinusENSEASP0000504478396.0693.4334
ENSG00000092621homo_sapiensENSP0000049317594.746789.3058capra_hircusENSCHIP0000001940594.746789.3058
ENSG00000092621homo_sapiensENSP0000049317596.247793.8086loxodonta_africanaENSLAFP0000000200396.247793.8086
ENSG00000092621homo_sapiensENSP0000049317596.998193.9962panthera_leoENSPLOP0000001568096.998193.9962
ENSG00000092621homo_sapiensENSP0000049317592.120189.8687ailuropoda_melanoleucaENSAMEP0000003634686.443784.331
ENSG00000092621homo_sapiensENSP0000049317590.994484.2402bos_indicus_hybridENSBIXP0000501875265.986461.0884
ENSG00000092621homo_sapiensENSP0000049317597.185793.9962oryctolagus_cuniculusENSOCUP0000000498890.401487.4346
ENSG00000092621homo_sapiensENSP0000049317596.0693.4334equus_caballusENSECAP0000000445794.814892.2222
ENSG00000092621homo_sapiensENSP0000049317590.806886.4916canis_lupus_familiarisENSCAFP0084500916082.876778.9384
ENSG00000092621homo_sapiensENSP0000049317595.872492.3077canis_lupus_familiarisENSCAFP0084501175296.052692.4812
ENSG00000092621homo_sapiensENSP0000049317596.998193.9962panthera_pardusENSPPRP0000002190996.998193.9962
ENSG00000092621homo_sapiensENSP0000049317597.748695.3096marmota_marmota_marmotaENSMMMP0000001741697.748695.3096
ENSG00000092621homo_sapiensENSP0000049317595.684891.7448balaenoptera_musculusENSBMSP0001000176595.684891.7448
ENSG00000092621homo_sapiensENSP0000049317594.746791.3696cavia_porcellusENSCPOP0000000606694.746791.3696
ENSG00000092621homo_sapiensENSP0000049317591.744888.3677felis_catusENSFCAP0000005853783.447180.3754
ENSG00000092621homo_sapiensENSP0000049317597.185795.1219ursus_americanusENSUAMP0000003270197.185795.1219
ENSG00000092621homo_sapiensENSP0000049317593.996287.0544monodelphis_domesticaENSMODP0000000669993.996287.0544
ENSG00000092621homo_sapiensENSP0000049317594.934389.8687bison_bison_bisonENSBBBP0000000845894.934389.8687
ENSG00000092621homo_sapiensENSP0000049317596.810592.1201monodon_monocerosENSMMNP0001500366496.810592.1201
ENSG00000092621homo_sapiensENSP0000049317595.121990.8068sus_scrofaENSSSCP0000006312988.327584.3206
ENSG00000092621homo_sapiensENSP0000049317596.998194.1839microcebus_murinusENSMICP0000000406496.998194.1839
ENSG00000092621homo_sapiensENSP0000049317595.497291.9325octodon_degusENSODEP0000000192595.497291.9325
ENSG00000092621homo_sapiensENSP0000049317581.613576.9231jaculus_jaculusENSJJAP0000001103592.356787.0488
ENSG00000092621homo_sapiensENSP0000049317576.172669.9812ovis_aries_rambouilletENSOARP0002000176370.36464.6447
ENSG00000092621homo_sapiensENSP0000049317597.185795.1219ursus_maritimusENSUMAP0000000021697.185795.1219
ENSG00000092621homo_sapiensENSP0000049317578.611675.4221ochotona_princepsENSOPRP0000000568385.685182.2086
ENSG00000092621homo_sapiensENSP0000049317596.810592.1201delphinapterus_leucasENSDLEP0000001172496.810592.1201
ENSG00000092621homo_sapiensENSP0000049317534.709233.2083physeter_catodonENSPCTP0000501919586.046582.3256
ENSG00000092621homo_sapiensENSP0000049317551.594748.03physeter_catodonENSPCTP0000502278187.025381.0127
ENSG00000092621homo_sapiensENSP0000049317525.891224.7655mus_caroliMGP_CAROLIEiJ_P005945493.243289.1892
ENSG00000092621homo_sapiensENSP0000049317596.998194.5591mus_musculusENSMUSP0000006475596.998194.5591
ENSG00000092621homo_sapiensENSP0000049317595.684890.4315dipodomys_ordiiENSDORP0000000801095.684890.4315
ENSG00000092621homo_sapiensENSP0000049317597.56194.9343mustela_putorius_furoENSMPUP0000000144297.56194.9343
ENSG00000092621homo_sapiensENSP0000049317599.061997.561aotus_nancymaaeENSANAP0000000428391.666790.2778
ENSG00000092621homo_sapiensENSP0000049317592.870591.182saimiri_boliviensis_boliviensisENSSBOP0000000571797.633195.858
ENSG00000092621homo_sapiensENSP0000049317567.917464.1651saimiri_boliviensis_boliviensisENSSBOP0000002205785.78281.0427
ENSG00000092621homo_sapiensENSP0000049317599.624899.2495chlorocebus_sabaeusENSCSAP0000001631099.624899.2495
ENSG00000092621homo_sapiensENSP0000049317570.168968.1051tupaia_belangeriENSTBEP0000000393470.168968.1051
ENSG00000092621homo_sapiensENSP0000049317578.986973.9212mesocricetus_auratusENSMAUP0000001459293.141687.1681
ENSG00000092621homo_sapiensENSP0000049317592.870586.6792phocoena_sinusENSPSNP0000000526479.326974.0385
ENSG00000092621homo_sapiensENSP0000049317595.309692.1201camelus_dromedariusENSCDRP0000500401495.309692.1201
ENSG00000092621homo_sapiensENSP0000049317566.416564.3527carlito_syrichtaENSTSYP0000001416873.90471.6075
ENSG00000092621homo_sapiensENSP0000049317596.810593.8086panthera_tigris_altaicaENSPTIP0000000203796.810593.8086
ENSG00000092621homo_sapiensENSP0000049317570.919366.4165rattus_norvegicusENSRNOP0000008364788.111982.5175
ENSG00000092621homo_sapiensENSP0000049317519.512218.1989rattus_norvegicusENSRNOP0000008616784.552878.8618
ENSG00000092621homo_sapiensENSP0000049317588.74386.4916rattus_norvegicusENSRNOP0000005301996.926294.4672
ENSG00000092621homo_sapiensENSP0000049317525.140721.3884rattus_norvegicusENSRNOP0000009488374.033162.9834
ENSG00000092621homo_sapiensENSP0000049317523.827421.3884rattus_norvegicusENSRNOP0000008332486.986378.0822
ENSG00000092621homo_sapiensENSP0000049317592.120187.4296prolemur_simusENSPSMP0000002239679.707875.6494
ENSG00000092621homo_sapiensENSP0000049317596.435393.621microtus_ochrogasterENSMOCP0000002230396.435393.621
ENSG00000092621homo_sapiensENSP0000049317589.681185.3659microtus_ochrogasterENSMOCP0000000641592.27887.8378
ENSG00000092621homo_sapiensENSP0000049317592.682989.3058microtus_ochrogasterENSMOCP0000000328894.63691.1877
ENSG00000092621homo_sapiensENSP0000049317576.547873.7336sorex_araneusENSSARP0000000388983.778280.6982
ENSG00000092621homo_sapiensENSP0000049317597.373494.5591peromyscus_maniculatus_bairdiiENSPEMP0000000350897.373494.5591
ENSG00000092621homo_sapiensENSP0000049317595.121989.6811bos_mutusENSBMUP0000001664195.121989.6811
ENSG00000092621homo_sapiensENSP0000049317521.388420.8255mus_spicilegusENSMSIP0000002689594.214991.7355
ENSG00000092621homo_sapiensENSP0000049317574.671771.8574mus_spicilegusENSMSIP0000000098192.129688.6574
ENSG00000092621homo_sapiensENSP0000049317524.390223.8274mus_spicilegusENSMSIP0000000217294.890592.7007
ENSG00000092621homo_sapiensENSP0000049317522.326521.7636mus_spicilegusENSMSIP0000000108887.585.2941
ENSG00000092621homo_sapiensENSP0000049317525.515924.5779mus_spicilegusENSMSIP0000002021286.07682.9114
ENSG00000092621homo_sapiensENSP0000049317596.998194.1839mus_spicilegusENSMSIP0000002697896.998194.1839
ENSG00000092621homo_sapiensENSP0000049317582.176476.3602cricetulus_griseus_chok1gshdENSCGRP0000101920387.077580.9145
ENSG00000092621homo_sapiensENSP0000049317596.998194.3715cricetulus_griseus_chok1gshdENSCGRP0000101479096.998194.3715
ENSG00000092621homo_sapiensENSP0000049317575.98574.2964pteropus_vampyrusENSPVAP0000001143375.98574.2964
ENSG00000092621homo_sapiensENSP0000049317596.622992.4953myotis_lucifugusENSMLUP0000000271996.261792.1495
ENSG00000092621homo_sapiensENSP0000049317594.559188.743vombatus_ursinusENSVURP0001001049686.74781.4114
ENSG00000092621homo_sapiensENSP0000049317528.517827.2045rhinolophus_ferrumequinumENSRFEP0001002116198.701394.1558
ENSG00000092621homo_sapiensENSP0000049317596.435392.8705rhinolophus_ferrumequinumENSRFEP0001002917696.435392.8705
ENSG00000092621homo_sapiensENSP0000049317596.998194.1839neovison_visonENSNVIP0000001169396.998194.1839
ENSG00000092621homo_sapiensENSP0000049317594.934389.6811bos_taurusENSBTAP0000000890794.934389.6811
ENSG00000092621homo_sapiensENSP0000049317596.622992.4953heterocephalus_glaber_femaleENSHGLP0000002603096.622992.4953
ENSG00000092621homo_sapiensENSP0000049317594.371593.0582rhinopithecus_bietiENSRBIP0000000132185.836284.6416
ENSG00000092621homo_sapiensENSP0000049317590.994486.3039canis_lupus_dingoENSCAFP0002002614783.620779.3103
ENSG00000092621homo_sapiensENSP0000049317590.994486.4916canis_lupus_dingoENSCAFP0002002573183.620779.4828
ENSG00000092621homo_sapiensENSP0000049317590.806886.3039canis_lupus_dingoENSCAFP0002002602483.448379.3103
ENSG00000092621homo_sapiensENSP0000049317597.936295.8724sciurus_vulgarisENSSVLP0000500250997.936295.8724
ENSG00000092621homo_sapiensENSP0000049317594.183987.0544phascolarctos_cinereusENSPCIP0000003213494.183987.0544
ENSG00000092621homo_sapiensENSP0000049317559.849956.4728procavia_capensisENSPCAP0000000128461.464457.9961
ENSG00000092621homo_sapiensENSP0000049317597.56194.3715nannospalax_galiliENSNGAP0000000753497.56194.3715
ENSG00000092621homo_sapiensENSP0000049317595.121989.6811bos_grunniensENSBGRP0000001993283.525578.7479
ENSG00000092621homo_sapiensENSP0000049317596.247792.1201chinchilla_lanigeraENSCLAP0000000853996.247792.1201
ENSG00000092621homo_sapiensENSP0000049317594.746789.8687cervus_hanglu_yarkandensisENSCHYP0000001728494.746789.8687
ENSG00000092621homo_sapiensENSP0000049317596.435392.8705catagonus_wagneriENSCWAP0000000286796.435392.8705
ENSG00000092621homo_sapiensENSP0000049317597.56195.1219ictidomys_tridecemlineatusENSSTOP0000000169997.56195.1219
ENSG00000092621homo_sapiensENSP0000049317594.934390.6191otolemur_garnettiiENSOGAP0000000245095.652291.3043
ENSG00000092621homo_sapiensENSP0000049317599.249597.3734cebus_imitatorENSCCAP0000001168599.249597.3734
ENSG00000092621homo_sapiensENSP0000049317567.917462.8518cebus_imitatorENSCCAP0000001658186.810680.3357
ENSG00000092621homo_sapiensENSP0000049317597.373494.7467urocitellus_parryiiENSUPAP0001001219497.373494.7467
ENSG00000092621homo_sapiensENSP0000049317594.934389.3058moschus_moschiferusENSMMSP0000001819194.934389.3058
ENSG00000092621homo_sapiensENSP0000049317594.371593.621rhinopithecus_roxellanaENSRROP0000004200791.788391.0584
ENSG00000092621homo_sapiensENSP0000049317594.559190.6191mus_pahariMGP_PahariEiJ_P007041194.559190.6191
ENSG00000092621homo_sapiensENSP0000049317596.435393.0582propithecus_coquereliENSPCOP0000000788696.435393.0582
ENSG00000092621homo_sapiensENSP0000049317542.964432.0826caenorhabditis_elegansC31C9.2.171.11853.1056
ENSG00000092621homo_sapiensENSP0000049317545.215833.0206drosophila_melanogasterFBpp007980972.590453.012
ENSG00000092621homo_sapiensENSP0000049317564.915647.6548ciona_intestinalisENSCINP0000003453765.779548.289
ENSG00000092621homo_sapiensENSP0000049317560.225148.5929petromyzon_marinusENSPMAP0000000611679.850764.4279
ENSG00000092621homo_sapiensENSP0000049317567.917451.7824eptatretus_burgeriENSEBUP0000002170262.847247.9167
ENSG00000092621homo_sapiensENSP0000049317568.855551.97latimeria_chalumnaeENSLACP0000001565770.306553.0651
ENSG00000092621homo_sapiensENSP0000049317578.611661.1632lepisosteus_oculatusENSLOCP0000000968578.171660.8209
ENSG00000092621homo_sapiensENSP0000049317575.98560.2251danio_rerioENSDARP0000002086076.704560.7955
ENSG00000092621homo_sapiensENSP0000049317574.296459.2871carassius_auratusENSCARP0000012329675.142359.962
ENSG00000092621homo_sapiensENSP0000049317574.859359.6623carassius_auratusENSCARP0000002865475.855560.4563
ENSG00000092621homo_sapiensENSP0000049317575.234557.7861astyanax_mexicanusENSAMXP0000000595774.259357.037
ENSG00000092621homo_sapiensENSP0000049317575.046957.9737ictalurus_punctatusENSIPUP0000001520775.18858.0827
ENSG00000092621homo_sapiensENSP0000049317576.360258.7242esox_luciusENSELUP0000002180269.572653.5043
ENSG00000092621homo_sapiensENSP0000049317573.733656.6604electrophorus_electricusENSEEEP0000003905474.714857.4144
ENSG00000092621homo_sapiensENSP0000049317575.609858.5366oncorhynchus_kisutchENSOKIP0000510388476.325859.0909
ENSG00000092621homo_sapiensENSP0000049317575.98559.0994oncorhynchus_kisutchENSOKIP0000502977476.704559.6591
ENSG00000092621homo_sapiensENSP0000049317576.360258.5366oncorhynchus_mykissENSOMYP0000005739076.217258.427
ENSG00000092621homo_sapiensENSP0000049317575.98558.9118oncorhynchus_mykissENSOMYP0000000346068.412253.0405
ENSG00000092621homo_sapiensENSP0000049317572.607955.7223salmo_salarENSSSAP0000016050375.585958.0078
ENSG00000092621homo_sapiensENSP0000049317573.54656.4728salmo_salarENSSSAP0000012068675.822158.2205
ENSG00000092621homo_sapiensENSP0000049317575.046957.9737salmo_truttaENSSTUP0000001089874.487957.5419
ENSG00000092621homo_sapiensENSP0000049317576.172658.9118salmo_truttaENSSTUP0000006542677.039859.5825
ENSG00000092621homo_sapiensENSP0000049317566.604150.469gadus_morhuaENSGMOP0000004231363.620148.2079
ENSG00000092621homo_sapiensENSP0000049317572.983156.848fundulus_heteroclitusENSFHEP0000002265273.53557.2779
ENSG00000092621homo_sapiensENSP0000049317573.358457.0356poecilia_reticulataENSPREP0000000524774.193657.685
ENSG00000092621homo_sapiensENSP0000049317573.733657.2233xiphophorus_maculatusENSXMAP0000002903374.291157.656
ENSG00000092621homo_sapiensENSP0000049317572.795557.0356oryzias_latipesENSORLP0000002150967.244452.6863
ENSG00000092621homo_sapiensENSP0000049317572.983154.9719cyclopterus_lumpusENSCLMP0000504818573.25855.1789
ENSG00000092621homo_sapiensENSP0000049317572.420355.1595oreochromis_niloticusENSONIP0000005321272.014954.8507
ENSG00000092621homo_sapiensENSP0000049317574.671757.0356haplochromis_burtoniENSHBUP0000002487775.236357.4669
ENSG00000092621homo_sapiensENSP0000049317574.671757.0356astatotilapia_callipteraENSACLP0000001598375.236357.4669
ENSG00000092621homo_sapiensENSP0000049317573.921255.5347sparus_aurataENSSAUP0001006645074.621256.0606
ENSG00000092621homo_sapiensENSP0000049317573.921257.4109lates_calcariferENSLCAP0001005181474.621257.9545
ENSG00000092621homo_sapiensENSP0000049317569.793655.9099xenopus_tropicalisENSXETP0000001867473.084558.5462
ENSG00000092621homo_sapiensENSP0000049317582.176469.606chrysemys_picta_belliiENSCPBP0000000506282.797770.1323
ENSG00000092621homo_sapiensENSP0000049317581.988769.9812sphenodon_punctatusENSSPUP0000000039476.265365.096
ENSG00000092621homo_sapiensENSP0000049317581.613571.2946crocodylus_porosusENSCPRP0000500423582.230671.8336
ENSG00000092621homo_sapiensENSP0000049317562.851852.3452laticauda_laticaudataENSLLTP0000001589477.90764.8837
ENSG00000092621homo_sapiensENSP0000049317579.362166.4165notechis_scutatusENSNSUP0000001455379.511366.5414
ENSG00000092621homo_sapiensENSP0000049317579.924966.6041pseudonaja_textilisENSPTXP0000000123680.075266.7293
ENSG00000092621homo_sapiensENSP0000049317581.988769.4184anas_platyrhynchos_platyrhynchosENSAPLP0000001981164.170354.3319
ENSG00000092621homo_sapiensENSP0000049317579.737367.167gallus_gallusENSGALP0001001901380.952468.1905
ENSG00000092621homo_sapiensENSP0000049317579.362167.3546meleagris_gallopavoENSMGAP0000000436980.571468.381
ENSG00000092621homo_sapiensENSP0000049317565.103254.409serinus_canariaENSSCAP0000000794274.623762.3656
ENSG00000092621homo_sapiensENSP0000049317570.919358.1614parus_majorENSPMJP0000001327765.968654.1012
ENSG00000092621homo_sapiensENSP0000049317580.300268.2927anolis_carolinensisENSACAP0000000980580.602668.5499
ENSG00000092621homo_sapiensENSP0000049317571.857454.9719neolamprologus_brichardiENSNBRP0000001657675.542457.7909
ENSG00000092621homo_sapiensENSP0000049317580.112666.6041naja_najaENSNNAP0000000629479.664266.2313
ENSG00000092621homo_sapiensENSP0000049317580.86367.167podarcis_muralisENSPMRP0000001100081.939268.0608
ENSG00000092621homo_sapiensENSP0000049317565.478455.1595geospiza_fortisENSGFOP0000001510580.229967.5862
ENSG00000092621homo_sapiensENSP0000049317581.425968.2927taeniopygia_guttataENSTGUP0000001953281.886868.6792
ENSG00000092621homo_sapiensENSP0000049317576.360260.2251erpetoichthys_calabaricusENSECRP0000001516577.083360.7955
ENSG00000092621homo_sapiensENSP0000049317573.54655.9099kryptolebias_marmoratusENSKMAP0000002141663.533248.2982
ENSG00000092621homo_sapiensENSP0000049317579.362167.167salvator_merianaeENSSMRP0000003068980.113667.803
ENSG00000092621homo_sapiensENSP0000049317572.795557.2233oryzias_javanicusENSOJAP0000005010173.484857.7652
ENSG00000092621homo_sapiensENSP0000049317573.733656.4728amphilophus_citrinellusENSACIP0000000236474.011356.6855
ENSG00000092621homo_sapiensENSP0000049317569.60652.9081dicentrarchus_labraxENSDLAP0000506017873.175555.6213
ENSG00000092621homo_sapiensENSP0000049317573.733656.848amphiprion_perculaENSAPEP0000002865774.291157.2779
ENSG00000092621homo_sapiensENSP0000049317569.230854.2214oryzias_sinensisENSOSIP0000004743466.247851.8851
ENSG00000092621homo_sapiensENSP0000049317582.739270.1689gopherus_evgoodeiENSGEVP0000500956983.364870.6994
ENSG00000092621homo_sapiensENSP0000049317562.288954.2214chelonoidis_abingdoniiENSCABP0000001374590.463278.7466
ENSG00000092621homo_sapiensENSP0000049317574.671757.7861seriola_dumeriliENSSDUP0000002778875.236358.2231
ENSG00000092621homo_sapiensENSP0000049317572.607954.5966cottoperca_gobioENSCGOP0000005211773.018954.9057
ENSG00000092621homo_sapiensENSP0000049317581.613568.4803anser_brachyrhynchusENSABRP0000002755782.230668.9981
ENSG00000092621homo_sapiensENSP0000049317572.983155.5347gasterosteus_aculeatusENSGACP0000000680573.53555.9546
ENSG00000092621homo_sapiensENSP0000049317574.484157.9737cynoglossus_semilaevisENSCSEP0000001805575.047358.4121
ENSG00000092621homo_sapiensENSP0000049317573.733657.2233poecilia_formosaENSPFOP0000000955773.048356.6914
ENSG00000092621homo_sapiensENSP0000049317574.484158.1614myripristis_murdjanENSMMDP0000505593574.484158.1614
ENSG00000092621homo_sapiensENSP0000049317573.733656.4728sander_luciopercaENSSLUP0000002116771.97855.1282
ENSG00000092621homo_sapiensENSP0000049317581.425968.8555strigops_habroptilaENSSHBP0000500634282.041669.3762
ENSG00000092621homo_sapiensENSP0000049317573.358456.848amphiprion_ocellarisENSAOCP0000002986573.91357.2779
ENSG00000092621homo_sapiensENSP0000049317582.36469.9812terrapene_carolina_triunguisENSTMTP0000002733482.986870.5104
ENSG00000092621homo_sapiensENSP0000049317582.36469.7936terrapene_carolina_triunguisENSTMTP0000000931182.986870.3214
ENSG00000092621homo_sapiensENSP0000049317576.172658.7242hucho_huchoENSHHUP0000007739777.039859.3928
ENSG00000092621homo_sapiensENSP0000049317574.296457.2233betta_splendensENSBSLP0000003758371.351354.955
ENSG00000092621homo_sapiensENSP0000049317515.759811.257pygocentrus_nattereriENSPNAP0000001123171.186450.8475
ENSG00000092621homo_sapiensENSP0000049317572.607955.7223anabas_testudineusENSATEP0000002460973.295556.25
ENSG00000092621homo_sapiensENSP0000049317539.399630.2064ciona_savignyiENSCSAVP0000001954579.545560.9848
ENSG00000092621homo_sapiensENSP0000049317539.399623.2645saccharomyces_cerevisiaeYIL074C44.776126.4392
ENSG00000092621homo_sapiensENSP0000049317540.150123.2645saccharomyces_cerevisiaeYER081W45.62926.4392
ENSG00000092621homo_sapiensENSP0000049317522.138813.1332saccharomyces_cerevisiaeYPL113C29.79817.6768
ENSG00000092621homo_sapiensENSP0000049317524.953114.8218saccharomyces_cerevisiaeYGL185C35.092420.8443
ENSG00000092621homo_sapiensENSP0000049317574.484157.7861seriola_lalandi_dorsalisENSSLDP0000000333175.047358.2231
ENSG00000092621homo_sapiensENSP0000049317573.733655.7223labrus_bergyltaENSLBEP0000002247774.291156.1437
ENSG00000092621homo_sapiensENSP0000049317571.857454.9719pundamilia_nyerereiENSPNYP0000000835775.691757.9051
ENSG00000092621homo_sapiensENSP0000049317573.54657.2233mastacembelus_armatusENSMAMP0000000700274.102157.656
ENSG00000092621homo_sapiensENSP0000049317573.358456.4728stegastes_partitusENSSPAP0000000740373.91356.8998
ENSG00000092621homo_sapiensENSP0000049317519.324611.6323oncorhynchus_tshawytschaENSOTSP0000504176151.758831.1558
ENSG00000092621homo_sapiensENSP0000049317573.54657.0356acanthochromis_polyacanthusENSAPOP0000000206374.102157.4669
ENSG00000092621homo_sapiensENSP0000049317580.675468.1051aquila_chrysaetos_chrysaetosENSACCP0002002354781.285468.62
ENSG00000092621homo_sapiensENSP0000049317572.795555.9099nothobranchius_furzeriENSNFUP0001505319573.345956.3327
ENSG00000092621homo_sapiensENSP0000049317572.983156.6604cyprinodon_variegatusENSCVAP0000003188973.53557.0888
ENSG00000092621homo_sapiensENSP0000049317575.422158.5366denticeps_clupeoidesENSDCDP0000001237169.19153.7005
ENSG00000092621homo_sapiensENSP0000049317572.795557.0356denticeps_clupeoidesENSDCDP0000000680668.551253.7102
ENSG00000092621homo_sapiensENSP0000049317574.296456.2852larimichthys_croceaENSLCRP0000503172673.880655.9701
ENSG00000092621homo_sapiensENSP0000049317568.667953.0957takifugu_rubripesENSTRUP0000004575978.038460.3412
ENSG00000092621homo_sapiensENSP0000049317578.236464.5403ficedula_albicollisENSFALP0000000388569.61657.429
ENSG00000092621homo_sapiensENSP0000049317574.296455.9099hippocampus_comesENSHCOP0000001537274.858256.3327
ENSG00000092621homo_sapiensENSP0000049317575.234560.2251cyprinus_carpio_carpioENSCCRP0000013517676.819961.4943
ENSG00000092621homo_sapiensENSP0000049317572.795556.6604cyprinus_carpio_carpioENSCCRP0000013094574.759258.1888
ENSG00000092621homo_sapiensENSP0000049317573.54657.0356poecilia_latipinnaENSPLAP0000002992474.102157.4669
ENSG00000092621homo_sapiensENSP0000049317515.572210.6942sinocyclocheilus_grahamiENSSGRP0000000023470.940248.7179
ENSG00000092621homo_sapiensENSP0000049317556.472844.4653sinocyclocheilus_grahamiENSSGRP0000000044366.008851.9737
ENSG00000092621homo_sapiensENSP0000049317575.046959.2871sinocyclocheilus_grahamiENSSGRP0000004207671.556456.5295
ENSG00000092621homo_sapiensENSP0000049317569.793653.4709maylandia_zebraENSMZEP0000500756077.178459.1286
ENSG00000092621homo_sapiensENSP0000049317571.857454.7842tetraodon_nigroviridisENSTNIP0000002004273.795856.262
ENSG00000092621homo_sapiensENSP0000049317575.609857.2233paramormyrops_kingsleyaeENSPKIP0000001787276.037757.5472
ENSG00000092621homo_sapiensENSP0000049317575.609859.0994scleropages_formosusENSSFOP0001503138065.422151.1364
ENSG00000092621homo_sapiensENSP0000049317569.793653.6585leptobrachium_leishanenseENSLLEP0000003449873.084556.1886
ENSG00000092621homo_sapiensENSP0000049317569.981255.1595scophthalmus_maximusENSSMAP0000002261871.319356.2141
ENSG00000092621homo_sapiensENSP0000049317573.358457.2233oryzias_melastigmaENSOMEP0000000222374.193657.8748

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0004617enables phosphoglycerate dehydrogenase activity1IBAHomo_sapiens(9606)Function
GO:0005829located_in cytosol1TASHomo_sapiens(9606)Component
GO:0006541involved_in glutamine metabolic process1IEAHomo_sapiens(9606)Process
GO:0006544involved_in glycine metabolic process1IEAHomo_sapiens(9606)Process
GO:0006564involved_in L-serine biosynthetic process1IEAHomo_sapiens(9606)Process
GO:0006566involved_in threonine metabolic process1IEAHomo_sapiens(9606)Process
GO:0007420involved_in brain development1TASHomo_sapiens(9606)Process
GO:0009055enables electron transfer activity1TASHomo_sapiens(9606)Function
GO:0009448involved_in gamma-aminobutyric acid metabolic process1IEAHomo_sapiens(9606)Process
GO:0010468involved_in regulation of gene expression1IEAHomo_sapiens(9606)Process
GO:0019530involved_in taurine metabolic process1IEAHomo_sapiens(9606)Process
GO:0021510involved_in spinal cord development1IEAHomo_sapiens(9606)Process
GO:0021782involved_in glial cell development1IEAHomo_sapiens(9606)Process
GO:0021915involved_in neural tube development1IEAHomo_sapiens(9606)Process
GO:0022900involved_in electron transport chain1IEAHomo_sapiens(9606)Process
GO:0030060enables L-malate dehydrogenase activity1IEAHomo_sapiens(9606)Function
GO:0031175involved_in neuron projection development1IEAHomo_sapiens(9606)Process
GO:0051287enables NAD binding1IEAHomo_sapiens(9606)Function
GO:0070062located_in extracellular exosome1HDAHomo_sapiens(9606)Component
GO:0070314involved_in G1 to G0 transition1IEAHomo_sapiens(9606)Process

Expression