Functions and Diseases

RBP Type Canonical_RBPs
Diseases Cancer
Drug N.A.
Main interacting RNAs N.A.
Moonlighting functions E3 ligase
Localizations N.A.
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000091732 Gene ID 51530 Accession 29913
Symbol ZC3HC1 Alias NIPA;HSPC216 Full Name zinc finger C3HC-type containing 1
Status Confidence Length 33165 bases Strand Minus strand
Position 7 : 130018287 - 130051451 RNA binding domain Rsm1 , zf-C3HC
Summary This gene encodes an F-box-containing protein that is a component of an SCF-type E3 ubiquitin ligase complex that regulates the onset of cell division. The G2/M transition in the cell cycle requires the interaction of the proteins cyclin B1 and cyclin-dependent kinase 1. The activated ubiquitin ligase complex targets the protein cyclin B1 for degradation, preventing this transition to mitosis. [provided by RefSeq, Aug 2013]

RNA binding domains (RBDs)

RNA binding proteomes (RBPomes)

Transcripts

Phenotypes

GWAS

Protein-Protein Interaction (PPI)

Orthologs

Gene Ontology

Expression