Ensembl ID
ENSG00000091732
Gene ID
51530
Accession
29913
Gene Symbol
ZC3HC1
Alias
NIPA;HSPC216
Full Name
zinc finger C3HC-type containing 1
Position
7 : 130018287 - 130051451
Length
33165 bases
Strand
Minus strand
Status
Confidence
Main interacting RNAs N.A. RBP type
Canonical_RBPs
Summary
This gene encodes an F-box-containing protein that is a component of an SCF-type E3 ubiquitin ligase complex that regulates the onset of cell division. The G2/M transition in the cell cycle requires the interaction of the proteins cyclin B1 and cyclin-dependent kinase 1. The activated ubiquitin ligase complex targets the protein cyclin B1 for degradation, preventing this transition to mitosis. [provided by RefSeq, Aug 2013]
ENSG00000091732 Expression In 33 Tumors
Ensembl ID
Gene symbol
Log2 Foldchange
Pvaue
Cancer
ENSG00000091732
ZC3HC1
0.90
4.60e-56
KIRC
ENSG00000091732
ZC3HC1
0.53
5.17e-17
LUSC
ENSG00000091732
ZC3HC1
0.95
1.86e-26
KIRP
ENSG00000091732
ZC3HC1
0.52
7.28e-15
LUAD
Ensembl ID
Gene symbol
Cancer types
Pubmed ID
ENSG00000091732
ZC3HC1
tumors
19904582
ENSG00000091732
ZC3HC1
lung cancer
26474281
ENSG00000091732
ZC3HC1
tumor
29464350
ENSG00000091732
ZC3HC1
cancer
30846795
Ensembl ID
Gene symbol
Disease/phenotype
Mutation type
Mutated / Total samples
Literature
Ensembl ID
Gene symbol
Cancer
P-value
Which worse
show
ENSG00000091732
ZC3HC1
MESO
0.042
low
show
ENSG00000091732
ZC3HC1
SARC
0.033
low
show
ENSG00000091732
ZC3HC1
PAAD
0.00072
low
show
ENSG00000091732
ZC3HC1
UCEC
0.00039
high
show
ENSG00000091732
ZC3HC1
THCA
0.027
high
show
ENSG00000091732
ZC3HC1
LGG
0.002
high
show
ENSG00000091732
ZC3HC1
LUSC
0.014
low
show
ENSG00000091732
ZC3HC1
HNSC
0.035
low
show
ENSG00000091732
ZC3HC1
KIRP
0.0039
low
show
ENSG00000091732
ZC3HC1
LUAD
0.037
high
show
ENSG00000091732
ZC3HC1
PCPG
0.00069
high
show
ENSG00000091732
ZC3HC1
THYM
0.00019
low
show
ENSG00000091732
ZC3HC1
BRCA
0.0088
low
show
ENSG00000091732
ZC3HC1
COAD
0.0059
high
show
ENSG00000091732
ZC3HC1
DLBC
0.0098
low
show
ENSG00000091732
ZC3HC1
KIRC
0.019
high
show
ENSG00000091732
ZC3HC1
SKCM
0.02
high
show
ENSG00000091732
ZC3HC1
CESC
0.031
high
show
Ensembl ID
Gene symbol
Cancer
CNV type
-log10(q-value)
G-score
average amplitude
frequency
ENSG00000091732
ZC3HC1
LUSC
Del
0.647007
0.064397
0.332160
0.165669
ENSG00000091732
ZC3HC1
LAML
Del
2.830737
0.058384
0.730149
0.125654
ENSG00000091732
ZC3HC1
LGG
Amp
6.759750
0.119150
0.680328
0.346979
ENSG00000091732
ZC3HC1
CESC
Del
1.049714
0.074501
0.499047
0.186441
ENSG00000091732
ZC3HC1
KIRP
Amp
2.934984
0.124729
0.958532
0.611111
ENSG00000091732
ZC3HC1
GBM
Amp
1.654213
0.084990
0.782748
0.828423
ENSG00000091732
ZC3HC1
PAAD
Del
0.810659
0.047660
0.362292
0.081522
ENSG00000091732
ZC3HC1
ESCA
Del
4.052308
0.179461
0.370914
0.331522
ENSG00000091732
ZC3HC1
SKCM
Amp
3.982240
0.216958
0.708959
0.599455
ENSG00000091732
ZC3HC1
HNSC
Del
10.400783
0.123820
0.396264
0.212644
ENSG00000091732
ZC3HC1
STAD
Del
0.966324
0.064566
0.343617
0.156463
ENSG00000091732
ZC3HC1
UCEC
Del
0.984535
0.051622
0.480081
0.103896
ENSG00000091732
ZC3HC1
OV
Amp
4.768305
0.445773
0.702481
0.521589
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