RBP Type
Non-canonical_RBPs
Diseases
Drug
N.A.
Main interacting RNAs
N.A.
Moonlighting functions
Metabolic enzyme
Localizations
N.A.
BulkPerturb-seq
N.A.
Ensembl ID ENSG00000091140 Gene ID
1738 Accession
2898
Symbol
DLD
Alias
E3;LAD;DLDD;DLDH;GCSL;PHE3;OGDC-E3
Full Name
dihydrolipoamide dehydrogenase
Status
Confidence
Length
40567 bases
Strand
Plus strand
Position
7 : 107891164 - 107931730
RNA binding domain
N.A.
Summary
This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. In homodimeric form, the encoded protein functions as a dehydrogenase and is found in several multi-enzyme complexes that regulate energy metabolism. However, as a monomer, this protein can function as a protease. Mutations in this gene have been identified in patients with E3-deficient maple syrup urine disease and lipoamide dehydrogenase deficiency. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
RNA binding domains (RBDs)
Protein
Domain
Pfam ID
E-value
Domain number
RNA binding proteomes (RBPomes)
Pubmed ID
Full Name
Cell
Author
Time
Doi
Literatures on RNA binding capacity
Pubmed ID
Title
Author
Time
Journal
Name
Transcript ID
bp
Protein
Translation ID
DLD-211
ENST00000485066
483
No protein
-
DLD-202
ENST00000415325
1802
58aa
ENSP00000402593
DLD-203
ENST00000417551
2041
509aa
ENSP00000390667
DLD-205
ENST00000440410
1993
486aa
ENSP00000417016
DLD-204
ENST00000437604
1859
461aa
ENSP00000387542
DLD-201
ENST00000205402
3537
509aa
ENSP00000205402
DLD-208
ENST00000453354
537
No protein
-
DLD-206
ENST00000450038
682
114aa
ENSP00000409590
DLD-207
ENST00000451081
930
115aa
ENSP00000388077
DLD-209
ENST00000460577
600
No protein
-
DLD-213
ENST00000494441
707
No protein
-
DLD-210
ENST00000478414
549
No protein
-
DLD-212
ENST00000489184
638
No protein
-
Pathway ID
Pathway Name
Source
ensgID
Trait
pValue
Pubmed ID
7078 P-Selectin 7.8151193195575E-5 17903293 7082 P-Selectin 2.53119544371057E-5 17903293
ensgID SNP Chromosome Position
Trait PubmedID Or or BEAT
EFO ID
Protein-Protein Interaction (PPI)
Ensembl ID
Source
Target
Species
Protein ID
Perc_pos
Perc_id
Species
Protein ID
Perc_pos
Perc_id
ENSG00000091140 homo_sapiens ENSP00000390798 31.2397 17.0248 homo_sapiens ENSP00000205402 37.1316 20.2358 ENSG00000091140 homo_sapiens ENSP00000430031 31.8818 19.7512 homo_sapiens ENSP00000205402 40.275 24.9509 ENSG00000091140 homo_sapiens ENSP00000240651 26.6 13.4 homo_sapiens ENSP00000205402 26.1297 13.1631 ENSG00000091140 homo_sapiens ENSP00000434516 32.0493 20.1849 homo_sapiens ENSP00000205402 40.8644 25.7367 ENSG00000091140 homo_sapiens ENSP00000383365 38.1679 24.4275 homo_sapiens ENSP00000205402 39.2927 25.1473 ENSG00000091140 homo_sapiens ENSP00000221130 34.2912 21.4559 homo_sapiens ENSP00000205402 35.167 22.0039 ENSG00000091140 homo_sapiens ENSP00000287295 24.633 14.3556 homo_sapiens ENSP00000205402 29.666 17.2888
Ensembl ID
Source
Target
Species
Protein ID
Perc_pos
Perc_id
Species
Protein ID
Perc_pos
Perc_id
ENSG00000091140 homo_sapiens ENSP00000205402 99.8035 99.4106 nomascus_leucogenys ENSNLEP00000046488 98.6408 98.2524 ENSG00000091140 homo_sapiens ENSP00000205402 100 99.8035 pan_paniscus ENSPPAP00000021843 94.6097 94.4238 ENSG00000091140 homo_sapiens ENSP00000205402 99.8035 99.6071 pongo_abelii ENSPPYP00000032523 99.8035 99.6071 ENSG00000091140 homo_sapiens ENSP00000205402 100 100 pan_troglodytes ENSPTRP00000086612 94.6097 94.6097 ENSG00000091140 homo_sapiens ENSP00000205402 99.4106 99.0177 gorilla_gorilla ENSGGOP00000044357 98.2524 97.8641 ENSG00000091140 homo_sapiens ENSP00000205402 95.8743 90.3733 ornithorhynchus_anatinus ENSOANP00000044691 95.8743 90.3733 ENSG00000091140 homo_sapiens ENSP00000205402 97.2495 90.5697 sarcophilus_harrisii ENSSHAP00000004480 97.4409 90.748 ENSG00000091140 homo_sapiens ENSP00000205402 67.9764 61.8861 notamacropus_eugenii ENSMEUP00000002337 69.899 63.6364 ENSG00000091140 homo_sapiens ENSP00000205402 91.945 89.1945 choloepus_hoffmanni ENSCHOP00000009499 94.3548 91.5323 ENSG00000091140 homo_sapiens ENSP00000205402 77.6031 75.0491 choloepus_hoffmanni ENSCHOP00000000876 85.3132 82.5054 ENSG00000091140 homo_sapiens ENSP00000205402 92.5344 89.7839 dasypus_novemcinctus ENSDNOP00000004928 92.1722 89.4325 ENSG00000091140 homo_sapiens ENSP00000205402 67.1906 59.332 dasypus_novemcinctus ENSDNOP00000028549 82.0144 72.4221 ENSG00000091140 homo_sapiens ENSP00000205402 97.053 92.7308 erinaceus_europaeus ENSEEUP00000006736 97.053 92.7308 ENSG00000091140 homo_sapiens ENSP00000205402 93.9096 91.945 echinops_telfairi ENSETEP00000009944 94.0945 92.126 ENSG00000091140 homo_sapiens ENSP00000205402 99.6071 98.8212 callithrix_jacchus ENSCJAP00000046551 99.6071 98.8212 ENSG00000091140 homo_sapiens ENSP00000205402 99.8035 99.0177 cercocebus_atys ENSCATP00000016720 98.2592 97.4855 ENSG00000091140 homo_sapiens ENSP00000205402 98.4283 97.446 macaca_fascicularis ENSMFAP00000062146 98.2353 97.2549 ENSG00000091140 homo_sapiens ENSP00000205402 98.4283 97.446 macaca_mulatta ENSMMUP00000044085 98.2353 97.2549 ENSG00000091140 homo_sapiens ENSP00000205402 99.6071 99.0177 macaca_nemestrina ENSMNEP00000036773 97.1264 96.5517 ENSG00000091140 homo_sapiens ENSP00000205402 99.8035 99.2141 papio_anubis ENSPANP00000011572 99.8035 99.2141 ENSG00000091140 homo_sapiens ENSP00000205402 99.8035 99.2141 mandrillus_leucophaeus ENSMLEP00000011814 95.4887 94.9248 ENSG00000091140 homo_sapiens ENSP00000205402 96.2672 94.6955 tursiops_truncatus ENSTTRP00000003766 98.7903 97.1774 ENSG00000091140 homo_sapiens ENSP00000205402 99.2141 98.4283 vulpes_vulpes ENSVVUP00000028412 99.2141 98.4283 ENSG00000091140 homo_sapiens ENSP00000205402 98.8212 94.8919 mus_spretus MGP_SPRETEiJ_P0033549 98.8212 94.8919 ENSG00000091140 homo_sapiens ENSP00000205402 99.4106 98.2318 equus_asinus ENSEASP00005025683 99.4106 98.2318 ENSG00000091140 homo_sapiens ENSP00000205402 99.2141 97.2495 capra_hircus ENSCHIP00000028694 99.2141 97.2495 ENSG00000091140 homo_sapiens ENSP00000205402 98.6248 96.6601 loxodonta_africana ENSLAFP00000028118 98.6248 96.6601 ENSG00000091140 homo_sapiens ENSP00000205402 99.4106 97.6424 panthera_leo ENSPLOP00000008442 99.4106 97.6424 ENSG00000091140 homo_sapiens ENSP00000205402 99.6071 98.6248 ailuropoda_melanoleuca ENSAMEP00000014710 99.6071 98.6248 ENSG00000091140 homo_sapiens ENSP00000205402 99.0177 97.446 bos_indicus_hybrid ENSBIXP00005026633 99.0177 97.446 ENSG00000091140 homo_sapiens ENSP00000205402 92.1415 90.9627 oryctolagus_cuniculus ENSOCUP00000047037 97.9123 96.6597 ENSG00000091140 homo_sapiens ENSP00000205402 96.6601 95.2849 oryctolagus_cuniculus ENSOCUP00000012612 99.1936 97.7823 ENSG00000091140 homo_sapiens ENSP00000205402 99.4106 98.2318 equus_caballus ENSECAP00000001815 99.4106 98.2318 ENSG00000091140 homo_sapiens ENSP00000205402 99.2141 98.2318 canis_lupus_familiaris ENSCAFP00845034820 98.8258 97.8474 ENSG00000091140 homo_sapiens ENSP00000205402 75.2456 71.3163 panthera_pardus ENSPPRP00000024632 85.4911 81.0268 ENSG00000091140 homo_sapiens ENSP00000205402 99.4106 97.8389 panthera_pardus ENSPPRP00000027066 99.4106 97.8389 ENSG00000091140 homo_sapiens ENSP00000205402 99.2141 98.0354 marmota_marmota_marmota ENSMMMP00000018572 99.2141 98.0354 ENSG00000091140 homo_sapiens ENSP00000205402 99.2141 97.446 balaenoptera_musculus ENSBMSP00010009707 99.2141 97.446 ENSG00000091140 homo_sapiens ENSP00000205402 94.6955 91.5521 cavia_porcellus ENSCPOP00000026353 96.2076 93.014 ENSG00000091140 homo_sapiens ENSP00000205402 99.4106 97.053 cavia_porcellus ENSCPOP00000004776 99.4106 97.053 ENSG00000091140 homo_sapiens ENSP00000205402 99.4106 98.2318 felis_catus ENSFCAP00000004133 99.4106 98.2318 ENSG00000091140 homo_sapiens ENSP00000205402 99.4106 98.4283 ursus_americanus ENSUAMP00000013114 99.4106 98.4283 ENSG00000091140 homo_sapiens ENSP00000205402 23.1827 20.6287 monodelphis_domestica ENSMODP00000051781 89.3939 79.5455 ENSG00000091140 homo_sapiens ENSP00000205402 90.1768 85.0688 monodelphis_domestica ENSMODP00000020394 98.0769 92.5214 ENSG00000091140 homo_sapiens ENSP00000205402 99.0177 97.446 bison_bison_bison ENSBBBP00000021426 99.0177 97.446 ENSG00000091140 homo_sapiens ENSP00000205402 77.2102 75.6385 monodon_monoceros ENSMMNP00015029058 95.8537 93.9024 ENSG00000091140 homo_sapiens ENSP00000205402 98.6248 97.2495 monodon_monoceros ENSMMNP00015018092 98.6248 97.2495 ENSG00000091140 homo_sapiens ENSP00000205402 96.4637 93.1238 sus_scrofa ENSSSCP00000061323 96.0861 92.7593 ENSG00000091140 homo_sapiens ENSP00000205402 97.446 96.2672 microcebus_murinus ENSMICP00000025672 95.0192 93.8697 ENSG00000091140 homo_sapiens ENSP00000205402 99.6071 97.6424 octodon_degus ENSODEP00000000916 99.6071 97.6424 ENSG00000091140 homo_sapiens ENSP00000205402 99.4106 96.6601 jaculus_jaculus ENSJJAP00000014680 99.4106 96.6601 ENSG00000091140 homo_sapiens ENSP00000205402 99.2141 97.446 ovis_aries_rambouillet ENSOARP00020017092 99.2141 97.446 ENSG00000091140 homo_sapiens ENSP00000205402 92.3379 89.9804 ursus_maritimus ENSUMAP00000024834 90.7336 88.417 ENSG00000091140 homo_sapiens ENSP00000205402 42.8291 41.2574 ochotona_princeps ENSOPRP00000013124 74.1497 71.4286 ENSG00000091140 homo_sapiens ENSP00000205402 98.8212 97.446 delphinapterus_leucas ENSDLEP00000002130 95.8095 94.4762 ENSG00000091140 homo_sapiens ENSP00000205402 87.4263 85.8546 delphinapterus_leucas ENSDLEP00000029919 89 87.4 ENSG00000091140 homo_sapiens ENSP00000205402 98.4283 96.8566 physeter_catodon ENSPCTP00005005080 98.4283 96.8566 ENSG00000091140 homo_sapiens ENSP00000205402 98.6248 94.8919 mus_caroli MGP_CAROLIEiJ_P0032074 98.6248 94.8919 ENSG00000091140 homo_sapiens ENSP00000205402 98.6248 94.8919 mus_musculus ENSMUSP00000106481 98.6248 94.8919 ENSG00000091140 homo_sapiens ENSP00000205402 93.3202 90.3733 dipodomys_ordii ENSDORP00000001465 96.7413 93.6864 ENSG00000091140 homo_sapiens ENSP00000205402 99.2141 98.2318 mustela_putorius_furo ENSMPUP00000018128 99.2141 98.2318 ENSG00000091140 homo_sapiens ENSP00000205402 93.1238 90.1768 aotus_nancymaae ENSANAP00000004604 89.2655 86.4407 ENSG00000091140 homo_sapiens ENSP00000205402 95.4813 94.6955 saimiri_boliviensis_boliviensis ENSSBOP00000021278 93.4615 92.6923 ENSG00000091140 homo_sapiens ENSP00000205402 87.8193 85.2652 vicugna_pacos ENSVPAP00000011618 90.121 87.5 ENSG00000091140 homo_sapiens ENSP00000205402 99.8035 99.2141 chlorocebus_sabaeus ENSCSAP00000007519 94.4238 93.8662 ENSG00000091140 homo_sapiens ENSP00000205402 89.9804 86.0511 tupaia_belangeri ENSTBEP00000011977 92.3387 88.3064 ENSG00000091140 homo_sapiens ENSP00000205402 98.6248 95.6778 mesocricetus_auratus ENSMAUP00000016215 98.4314 95.4902 ENSG00000091140 homo_sapiens ENSP00000205402 99.0177 97.446 phocoena_sinus ENSPSNP00000006387 99.0177 97.446 ENSG00000091140 homo_sapiens ENSP00000205402 87.8193 85.6581 phocoena_sinus ENSPSNP00000005129 91.7864 89.5277 ENSG00000091140 homo_sapiens ENSP00000205402 99.2141 96.4637 camelus_dromedarius ENSCDRP00005008880 99.2141 96.4637 ENSG00000091140 homo_sapiens ENSP00000205402 91.7485 88.6051 carlito_syrichta ENSTSYP00000023192 90.5039 87.4031 ENSG00000091140 homo_sapiens ENSP00000205402 95.6778 94.499 carlito_syrichta ENSTSYP00000033988 94.3798 93.2171 ENSG00000091140 homo_sapiens ENSP00000205402 99.4106 97.8389 panthera_tigris_altaica ENSPTIP00000004256 99.4106 97.8389 ENSG00000091140 homo_sapiens ENSP00000205402 80.7466 76.4244 rattus_norvegicus ENSRNOP00000089087 84.9174 80.3719 ENSG00000091140 homo_sapiens ENSP00000205402 96.4637 92.7308 rattus_norvegicus ENSRNOP00000084511 91.2639 87.7323 ENSG00000091140 homo_sapiens ENSP00000205402 99.2141 98.4283 prolemur_simus ENSPSMP00000021212 93.5185 92.7778 ENSG00000091140 homo_sapiens ENSP00000205402 99.2141 97.446 microtus_ochrogaster ENSMOCP00000024661 99.2141 97.446 ENSG00000091140 homo_sapiens ENSP00000205402 88.8016 86.8369 sorex_araneus ENSSARP00000004327 88.8016 86.8369 ENSG00000091140 homo_sapiens ENSP00000205402 99.4106 97.446 peromyscus_maniculatus_bairdii ENSPEMP00000027655 99.4106 97.446 ENSG00000091140 homo_sapiens ENSP00000205402 99.0177 97.2495 bos_mutus ENSBMUP00000030776 99.0177 97.2495 ENSG00000091140 homo_sapiens ENSP00000205402 98.6248 94.8919 mus_spicilegus ENSMSIP00000003982 76.9939 74.0798 ENSG00000091140 homo_sapiens ENSP00000205402 90.7662 86.8369 cricetulus_griseus_chok1gshd ENSCGRP00001000070 93.1452 89.1129 ENSG00000091140 homo_sapiens ENSP00000205402 99.2141 96.4637 cricetulus_griseus_chok1gshd ENSCGRP00001009069 99.2141 96.4637 ENSG00000091140 homo_sapiens ENSP00000205402 89.1945 87.6228 pteropus_vampyrus ENSPVAP00000006582 89.1945 87.6228 ENSG00000091140 homo_sapiens ENSP00000205402 92.1415 89.7839 myotis_lucifugus ENSMLUP00000015846 98.1172 95.6067 ENSG00000091140 homo_sapiens ENSP00000205402 97.6424 90.5697 vombatus_ursinus ENSVURP00010013393 97.8346 90.748 ENSG00000091140 homo_sapiens ENSP00000205402 99.4106 96.6601 rhinolophus_ferrumequinum ENSRFEP00010027963 99.4106 96.6601 ENSG00000091140 homo_sapiens ENSP00000205402 99.4106 98.4283 neovison_vison ENSNVIP00000026143 99.4106 98.4283 ENSG00000091140 homo_sapiens ENSP00000205402 99.0177 97.446 bos_taurus ENSBTAP00000033696 99.0177 97.446 ENSG00000091140 homo_sapiens ENSP00000205402 98.8212 96.6601 heterocephalus_glaber_female ENSHGLP00000010171 98.8212 96.6601 ENSG00000091140 homo_sapiens ENSP00000205402 95.6778 94.8919 rhinopithecus_bieti ENSRBIP00000016470 99.591 98.773 ENSG00000091140 homo_sapiens ENSP00000205402 99.2141 98.2318 canis_lupus_dingo ENSCAFP00020029673 99.2141 98.2318 ENSG00000091140 homo_sapiens ENSP00000205402 99.0177 97.8389 sciurus_vulgaris ENSSVLP00005031206 99.0177 97.8389 ENSG00000091140 homo_sapiens ENSP00000205402 97.6424 91.1591 phascolarctos_cinereus ENSPCIP00000005871 97.8346 91.3386 ENSG00000091140 homo_sapiens ENSP00000205402 84.8723 80.5501 procavia_capensis ENSPCAP00000008886 86.9215 82.495 ENSG00000091140 homo_sapiens ENSP00000205402 99.2141 96.2672 nannospalax_galili ENSNGAP00000001658 99.2141 96.2672 ENSG00000091140 homo_sapiens ENSP00000205402 79.3713 75.835 nannospalax_galili ENSNGAP00000009655 94.1725 89.9767 ENSG00000091140 homo_sapiens ENSP00000205402 90.3733 86.0511 nannospalax_galili ENSNGAP00000020477 94.2623 89.7541 ENSG00000091140 homo_sapiens ENSP00000205402 99.0177 97.446 bos_grunniens ENSBGRP00000009019 98.8235 97.2549 ENSG00000091140 homo_sapiens ENSP00000205402 99.4106 97.053 chinchilla_lanigera ENSCLAP00000008996 99.4106 97.053 ENSG00000091140 homo_sapiens ENSP00000205402 99.2141 97.2495 cervus_hanglu_yarkandensis ENSCHYP00000007740 99.2141 97.2495 ENSG00000091140 homo_sapiens ENSP00000205402 99.2141 97.2495 catagonus_wagneri ENSCWAP00000018475 99.2141 97.2495 ENSG00000091140 homo_sapiens ENSP00000205402 99.4106 97.8389 ictidomys_tridecemlineatus ENSSTOP00000006659 99.4106 97.8389 ENSG00000091140 homo_sapiens ENSP00000205402 86.444 85.8546 otolemur_garnettii ENSOGAP00000003335 95.4447 94.7939 ENSG00000091140 homo_sapiens ENSP00000205402 99.8035 98.8212 cebus_imitator ENSCCAP00000015317 99.8035 98.8212 ENSG00000091140 homo_sapiens ENSP00000205402 96.6601 93.5167 urocitellus_parryii ENSUPAP00010017807 96.2818 93.1507 ENSG00000091140 homo_sapiens ENSP00000205402 99.0177 97.446 moschus_moschiferus ENSMMSP00000018353 99.0177 97.446 ENSG00000091140 homo_sapiens ENSP00000205402 99.8035 99.4106 rhinopithecus_roxellana ENSRROP00000033959 98.6408 98.2524 ENSG00000091140 homo_sapiens ENSP00000205402 98.8212 95.0884 mus_pahari MGP_PahariEiJ_P0082192 98.8212 95.0884 ENSG00000091140 homo_sapiens ENSP00000205402 99.0177 98.0354 propithecus_coquereli ENSPCOP00000026841 97.6744 96.7054 ENSG00000091140 homo_sapiens ENSP00000205402 77.9961 68.9587 caenorhabditis_elegans LLC1.3a.1 80.202 70.9091 ENSG00000091140 homo_sapiens ENSP00000205402 78.5855 66.7976 drosophila_melanogaster FBpp0074906 79.3651 67.4603 ENSG00000091140 homo_sapiens ENSP00000205402 81.9253 73.2809 ciona_intestinalis ENSCINP00000016324 81.9253 73.2809 ENSG00000091140 homo_sapiens ENSP00000205402 89.7839 80.1572 petromyzon_marinus ENSPMAP00000006178 89.9606 80.315 ENSG00000091140 homo_sapiens ENSP00000205402 86.0511 76.2279 eptatretus_burgeri ENSEBUP00000001274 91.4405 81.0021 ENSG00000091140 homo_sapiens ENSP00000205402 90.9627 82.1218 callorhinchus_milii ENSCMIP00000017732 91.502 82.6087 ENSG00000091140 homo_sapiens ENSP00000205402 44.2043 40.0786 latimeria_chalumnae ENSLACP00000002388 95.339 86.4407 ENSG00000091140 homo_sapiens ENSP00000205402 36.7387 31.4342 latimeria_chalumnae ENSLACP00000009564 80.2575 68.6695 ENSG00000091140 homo_sapiens ENSP00000205402 92.9273 83.89 lepisosteus_oculatus ENSLOCP00000019577 88.743 80.1126 ENSG00000091140 homo_sapiens ENSP00000205402 89.5874 80.5501 clupea_harengus ENSCHAP00000053690 89.4118 80.3922 ENSG00000091140 homo_sapiens ENSP00000205402 90.5697 81.1395 clupea_harengus ENSCHAP00000043949 90.748 81.2992 ENSG00000091140 homo_sapiens ENSP00000205402 90.5697 83.1041 danio_rerio ENSDARP00000017217 90.927 83.432 ENSG00000091140 homo_sapiens ENSP00000205402 88.2122 79.1749 carassius_auratus ENSCARP00000120899 85.5238 76.7619 ENSG00000091140 homo_sapiens ENSP00000205402 91.3556 82.7112 carassius_auratus ENSCARP00000130137 91.716 83.0375 ENSG00000091140 homo_sapiens ENSP00000205402 91.5521 82.3183 astyanax_mexicanus ENSAMXP00000049257 91.7323 82.4803 ENSG00000091140 homo_sapiens ENSP00000205402 90.7662 81.9253 ictalurus_punctatus ENSIPUP00000029464 90.9449 82.0866 ENSG00000091140 homo_sapiens ENSP00000205402 87.8193 78.7819 esox_lucius ENSELUP00000046054 87.6471 78.6274 ENSG00000091140 homo_sapiens ENSP00000205402 90.7662 81.7289 electrophorus_electricus ENSEEEP00000018723 91.1243 82.0513 ENSG00000091140 homo_sapiens ENSP00000205402 89.391 79.5678 oncorhynchus_kisutch ENSOKIP00005075663 84.5725 75.2788 ENSG00000091140 homo_sapiens ENSP00000205402 89.9804 80.7466 oncorhynchus_kisutch ENSOKIP00005065419 87.7395 78.7356 ENSG00000091140 homo_sapiens ENSP00000205402 91.3556 82.1218 oncorhynchus_mykiss ENSOMYP00000097230 91.716 82.4458 ENSG00000091140 homo_sapiens ENSP00000205402 91.3556 82.1218 oncorhynchus_mykiss ENSOMYP00000104244 91.5354 82.2835 ENSG00000091140 homo_sapiens ENSP00000205402 89.5874 79.1749 salmo_salar ENSSSAP00000061073 84.6011 74.7681 ENSG00000091140 homo_sapiens ENSP00000205402 86.0511 76.0314 salmo_salar ENSSSAP00000117640 79.927 70.6204 ENSG00000091140 homo_sapiens ENSP00000205402 89.391 79.5678 salmo_trutta ENSSTUP00000041411 85.8491 76.4151 ENSG00000091140 homo_sapiens ENSP00000205402 90.1768 81.1395 salmo_trutta ENSSTUP00000022904 87.931 79.1188 ENSG00000091140 homo_sapiens ENSP00000205402 90.1768 80.5501 gadus_morhua ENSGMOP00000018113 90.3543 80.7087 ENSG00000091140 homo_sapiens ENSP00000205402 89.5874 81.7289 fundulus_heteroclitus ENSFHEP00000026455 88.716 80.9339 ENSG00000091140 homo_sapiens ENSP00000205402 91.3556 82.9077 poecilia_reticulata ENSPREP00000003162 91.5354 83.0709 ENSG00000091140 homo_sapiens ENSP00000205402 91.1591 82.9077 xiphophorus_maculatus ENSXMAP00000013428 91.3386 83.0709 ENSG00000091140 homo_sapiens ENSP00000205402 91.7485 82.1218 oryzias_latipes ENSORLP00000000566 92.1105 82.4458 ENSG00000091140 homo_sapiens ENSP00000205402 91.7485 81.1395 cyclopterus_lumpus ENSCLMP00005013967 93.0279 82.2709 ENSG00000091140 homo_sapiens ENSP00000205402 92.3379 83.4971 oreochromis_niloticus ENSONIP00000013540 92.5197 83.6614 ENSG00000091140 homo_sapiens ENSP00000205402 92.3379 83.3006 haplochromis_burtoni ENSHBUP00000009321 92.5197 83.4646 ENSG00000091140 homo_sapiens ENSP00000205402 92.3379 83.3006 astatotilapia_calliptera ENSACLP00000001913 92.5197 83.4646 ENSG00000091140 homo_sapiens ENSP00000205402 91.3556 82.3183 sparus_aurata ENSSAUP00010012169 91.5354 82.4803 ENSG00000091140 homo_sapiens ENSP00000205402 88.998 79.9607 lates_calcarifer ENSLCAP00010026638 86.6157 77.8203 ENSG00000091140 homo_sapiens ENSP00000205402 91.3556 84.0864 xenopus_tropicalis ENSXETP00000076253 90.998 83.7573 ENSG00000091140 homo_sapiens ENSP00000205402 95.2849 88.6051 chrysemys_picta_bellii ENSCPBP00000000834 95.4724 88.7795 ENSG00000091140 homo_sapiens ENSP00000205402 95.6778 88.0157 sphenodon_punctatus ENSSPUP00000024874 95.8661 88.189 ENSG00000091140 homo_sapiens ENSP00000205402 95.0884 88.4086 crocodylus_porosus ENSCPRP00005019579 95.2756 88.5827 ENSG00000091140 homo_sapiens ENSP00000205402 16.5029 15.3242 laticauda_laticaudata ENSLLTP00000018123 90.3226 83.871 ENSG00000091140 homo_sapiens ENSP00000205402 95.0884 88.6051 notechis_scutatus ENSNSUP00000027645 95.2756 88.7795 ENSG00000091140 homo_sapiens ENSP00000205402 95.0884 88.998 pseudonaja_textilis ENSPTXP00000016995 95.2756 89.1732 ENSG00000091140 homo_sapiens ENSP00000205402 87.0334 81.336 anas_platyrhynchos_platyrhynchos ENSAPLP00000009721 94.8608 88.651 ENSG00000091140 homo_sapiens ENSP00000205402 95.6778 89.391 gallus_gallus ENSGALP00010012757 95.8661 89.5669 ENSG00000091140 homo_sapiens ENSP00000205402 95.6778 89.5874 meleagris_gallopavo ENSMGAP00000010291 95.8661 89.7638 ENSG00000091140 homo_sapiens ENSP00000205402 94.499 88.4086 serinus_canaria ENSSCAP00000008464 85.5872 80.0712 ENSG00000091140 homo_sapiens ENSP00000205402 95.8743 90.1768 parus_major ENSPMJP00000006288 96.063 90.3543 ENSG00000091140 homo_sapiens ENSP00000205402 93.3202 85.8546 anolis_carolinensis ENSACAP00000015108 94.4334 86.8787 ENSG00000091140 homo_sapiens ENSP00000205402 85.2652 76.6208 neolamprologus_brichardi ENSNBRP00000000570 92.735 83.3333 ENSG00000091140 homo_sapiens ENSP00000205402 95.4813 88.8016 naja_naja ENSNNAP00000026893 95.6693 88.9764 ENSG00000091140 homo_sapiens ENSP00000205402 90.5697 82.7112 podarcis_muralis ENSPMRP00000017732 83.5145 76.2681 ENSG00000091140 homo_sapiens ENSP00000205402 91.5521 85.6581 geospiza_fortis ENSGFOP00000021609 97.286 91.023 ENSG00000091140 homo_sapiens ENSP00000205402 95.0884 88.4086 taeniopygia_guttata ENSTGUP00000003349 88.8073 82.5688 ENSG00000091140 homo_sapiens ENSP00000205402 90.7662 80.943 erpetoichthys_calabaricus ENSECRP00000001789 87.8327 78.327 ENSG00000091140 homo_sapiens ENSP00000205402 91.5521 82.1218 kryptolebias_marmoratus ENSKMAP00000018385 91.7323 82.2835 ENSG00000091140 homo_sapiens ENSP00000205402 94.1061 86.2475 salvator_merianae ENSSMRP00000020059 91.9386 84.261 ENSG00000091140 homo_sapiens ENSP00000205402 89.391 79.7642 oryzias_javanicus ENSOJAP00000008904 89.2157 79.6078 ENSG00000091140 homo_sapiens ENSP00000205402 89.391 81.5324 amphilophus_citrinellus ENSACIP00000019403 92.2921 84.1785 ENSG00000091140 homo_sapiens ENSP00000205402 91.5521 82.9077 dicentrarchus_labrax ENSDLAP00005070694 91.7323 83.0709 ENSG00000091140 homo_sapiens ENSP00000205402 92.3379 83.4971 amphiprion_percula ENSAPEP00000023091 92.5197 83.6614 ENSG00000091140 homo_sapiens ENSP00000205402 75.835 67.78 oryzias_sinensis ENSOSIP00000011742 90.8235 81.1765 ENSG00000091140 homo_sapiens ENSP00000205402 84.2829 75.0491 oryzias_sinensis ENSOSIP00000007714 78.4278 69.8355 ENSG00000091140 homo_sapiens ENSP00000205402 93.3202 86.2475 pelodiscus_sinensis ENSPSIP00000008194 93.3202 86.2475 ENSG00000091140 homo_sapiens ENSP00000205402 94.6955 88.4086 gopherus_evgoodei ENSGEVP00005001375 94.8819 88.5827 ENSG00000091140 homo_sapiens ENSP00000205402 94.8919 88.0157 chelonoidis_abingdonii ENSCABP00000022591 95.0787 88.189 ENSG00000091140 homo_sapiens ENSP00000205402 92.1415 83.6935 seriola_dumerili ENSSDUP00000023751 92.3228 83.8583 ENSG00000091140 homo_sapiens ENSP00000205402 91.3556 81.336 cottoperca_gobio ENSCGOP00000018761 91.5354 81.4961 ENSG00000091140 homo_sapiens ENSP00000205402 94.3026 88.4086 struthio_camelus_australis ENSSCUP00000001519 92.1305 86.3724 ENSG00000091140 homo_sapiens ENSP00000205402 95.6778 89.5874 anser_brachyrhynchus ENSABRP00000027775 95.8661 89.7638 ENSG00000091140 homo_sapiens ENSP00000205402 91.5521 82.7112 gasterosteus_aculeatus ENSGACP00000010969 91.7323 82.874 ENSG00000091140 homo_sapiens ENSP00000205402 91.945 82.1218 cynoglossus_semilaevis ENSCSEP00000002445 92.126 82.2835 ENSG00000091140 homo_sapiens ENSP00000205402 91.3556 83.3006 poecilia_formosa ENSPFOP00000013964 91.5354 83.4646 ENSG00000091140 homo_sapiens ENSP00000205402 90.3733 81.336 myripristis_murdjan ENSMMDP00005022560 80.1394 72.1254 ENSG00000091140 homo_sapiens ENSP00000205402 88.6051 80.1572 sander_lucioperca ENSSLUP00000021132 90.02 81.4371 ENSG00000091140 homo_sapiens ENSP00000205402 95.6778 89.7839 strigops_habroptila ENSSHBP00005014223 95.8661 89.9606 ENSG00000091140 homo_sapiens ENSP00000205402 92.3379 83.4971 amphiprion_ocellaris ENSAOCP00000013055 92.5197 83.6614 ENSG00000091140 homo_sapiens ENSP00000205402 91.3556 84.4794 terrapene_carolina_triunguis ENSTMTP00000008298 84.2391 77.8986 ENSG00000091140 homo_sapiens ENSP00000205402 88.998 79.1749 hucho_hucho ENSHHUP00000002895 73.7785 65.6352 ENSG00000091140 homo_sapiens ENSP00000205402 91.1591 81.7289 hucho_hucho ENSHHUP00000004602 88.5496 79.3893 ENSG00000091140 homo_sapiens ENSP00000205402 91.7485 82.5147 betta_splendens ENSBSLP00000016025 91.9291 82.6772 ENSG00000091140 homo_sapiens ENSP00000205402 91.1591 81.9253 pygocentrus_nattereri ENSPNAP00000011020 91.3386 82.0866 ENSG00000091140 homo_sapiens ENSP00000205402 91.945 82.3183 anabas_testudineus ENSATEP00000014583 92.126 82.4803 ENSG00000091140 homo_sapiens ENSP00000205402 81.5324 72.6916 ciona_savignyi ENSCSAVP00000001418 82.505 73.5586 ENSG00000091140 homo_sapiens ENSP00000205402 51.4735 31.2377 saccharomyces_cerevisiae YPL017C 52.505 31.8637 ENSG00000091140 homo_sapiens ENSP00000205402 78.9784 70.7269 seriola_lalandi_dorsalis ENSSLDP00000005513 87.2017 78.0911 ENSG00000091140 homo_sapiens ENSP00000205402 88.4086 80.5501 labrus_bergylta ENSLBEP00000005862 92.5926 84.3621 ENSG00000091140 homo_sapiens ENSP00000205402 92.1415 83.1041 pundamilia_nyererei ENSPNYP00000025573 92.3228 83.2677 ENSG00000091140 homo_sapiens ENSP00000205402 92.3379 83.1041 mastacembelus_armatus ENSMAMP00000033847 91.7969 82.6172 ENSG00000091140 homo_sapiens ENSP00000205402 88.8016 80.7466 stegastes_partitus ENSSPAP00000009415 90.9457 82.6962 ENSG00000091140 homo_sapiens ENSP00000205402 49.5088 33.5953 oncorhynchus_tshawytscha ENSOTSP00005042142 65.4545 44.4156 ENSG00000091140 homo_sapiens ENSP00000205402 89.7839 80.3536 acanthochromis_polyacanthus ENSAPOP00000004981 81.1723 72.6465 ENSG00000091140 homo_sapiens ENSP00000205402 95.2849 89.7839 aquila_chrysaetos_chrysaetos ENSACCP00020014061 95.4724 89.9606 ENSG00000091140 homo_sapiens ENSP00000205402 91.3556 82.5147 nothobranchius_furzeri ENSNFUP00015009907 78.4148 70.8263 ENSG00000091140 homo_sapiens ENSP00000205402 91.5521 82.7112 cyprinodon_variegatus ENSCVAP00000025540 91.7323 82.874 ENSG00000091140 homo_sapiens ENSP00000205402 91.1591 82.9077 denticeps_clupeoides ENSDCDP00000031946 91.3386 83.0709 ENSG00000091140 homo_sapiens ENSP00000205402 92.1415 83.1041 larimichthys_crocea ENSLCRP00005054151 92.3228 83.2677 ENSG00000091140 homo_sapiens ENSP00000205402 91.3556 82.1218 takifugu_rubripes ENSTRUP00000042609 91.5354 82.2835 ENSG00000091140 homo_sapiens ENSP00000205402 90.9627 84.8723 ficedula_albicollis ENSFALP00000010588 95.0719 88.7064 ENSG00000091140 homo_sapiens ENSP00000205402 91.1591 81.5324 hippocampus_comes ENSHCOP00000022268 91.3386 81.6929 ENSG00000091140 homo_sapiens ENSP00000205402 87.8193 79.7642 cyprinus_carpio_carpio ENSCCRP00000147341 87.8193 79.7642 ENSG00000091140 homo_sapiens ENSP00000205402 91.7485 82.3183 cyprinus_carpio_carpio ENSCCRP00000114351 92.1105 82.643 ENSG00000091140 homo_sapiens ENSP00000205402 96.0707 90.1768 coturnix_japonica ENSCJPP00005007606 83.0221 77.9287 ENSG00000091140 homo_sapiens ENSP00000205402 79.9607 73.2809 poecilia_latipinna ENSPLAP00000000668 93.5632 85.7471 ENSG00000091140 homo_sapiens ENSP00000205402 62.8684 53.6346 sinocyclocheilus_grahami ENSSGRP00000036614 79.602 67.9104 ENSG00000091140 homo_sapiens ENSP00000205402 87.0334 78.9784 sinocyclocheilus_grahami ENSSGRP00000086871 86.5234 78.5156 ENSG00000091140 homo_sapiens ENSP00000205402 86.2475 77.6031 sinocyclocheilus_grahami ENSSGRP00000019647 88.8664 79.9595 ENSG00000091140 homo_sapiens ENSP00000205402 92.3379 83.3006 maylandia_zebra ENSMZEP00005021507 92.5197 83.4646 ENSG00000091140 homo_sapiens ENSP00000205402 91.3556 82.3183 tetraodon_nigroviridis ENSTNIP00000007143 91.3556 82.3183 ENSG00000091140 homo_sapiens ENSP00000205402 91.945 82.5147 paramormyrops_kingsleyae ENSPKIP00000036996 92.126 82.6772 ENSG00000091140 homo_sapiens ENSP00000205402 90.1768 80.943 scleropages_formosus ENSSFOP00015065390 89.2996 80.1556 ENSG00000091140 homo_sapiens ENSP00000205402 94.8919 87.8193 leptobrachium_leishanense ENSLLEP00000007175 94.8919 87.8193 ENSG00000091140 homo_sapiens ENSP00000205402 91.7485 83.1041 scophthalmus_maximus ENSSMAP00000035970 91.9291 83.2677 ENSG00000091140 homo_sapiens ENSP00000205402 91.945 83.1041 oryzias_melastigma ENSOMEP00000011472 92.126 83.2677
Go ID
Go term
No. evidence
Entries
Species
Category
GO:0004148 enables dihydrolipoyl dehydrogenase activity 2 IBA,IDA Homo_sapiens(9606) Function GO:0005515 enables protein binding 1 IPI Homo_sapiens(9606) Function GO:0005634 located_in nucleus 1 IDA Homo_sapiens(9606) Component GO:0005739 located_in mitochondrion 4 HDA,IBA,IDA,NAS Homo_sapiens(9606) Component GO:0005759 located_in mitochondrial matrix 2 NAS,TAS Homo_sapiens(9606) Component GO:0005947 part_of mitochondrial alpha-ketoglutarate dehydrogenase complex 1 IPI Homo_sapiens(9606) Component GO:0005967 part_of mitochondrial pyruvate dehydrogenase complex 2 IPI,ISS Homo_sapiens(9606) Component GO:0006086 acts_upstream_of_or_within acetyl-CoA biosynthetic process from pyruvate 3 IC,IDA,ISS Homo_sapiens(9606) Process GO:0006120 involved_in mitochondrial electron transport, NADH to ubiquinone 1 IEA Homo_sapiens(9606) Process GO:0006508 involved_in proteolysis 1 IEA Homo_sapiens(9606) Process GO:0007369 involved_in gastrulation 1 IEA Homo_sapiens(9606) Process GO:0009083 involved_in branched-chain amino acid catabolic process 1 IDA Homo_sapiens(9606) Process GO:0031514 located_in motile cilium 1 IEA Homo_sapiens(9606) Component GO:0034604 contributes_to pyruvate dehydrogenase (NAD+) activity 1 IDA Homo_sapiens(9606) Function GO:0042391 involved_in regulation of membrane potential 1 IEA Homo_sapiens(9606) Process GO:0043159 located_in acrosomal matrix 1 IEA Homo_sapiens(9606) Component GO:0045252 part_of oxoglutarate dehydrogenase complex 2 IBA,IDA Homo_sapiens(9606) Component GO:0045254 part_of pyruvate dehydrogenase complex 1 IDA Homo_sapiens(9606) Component GO:0048240 involved_in sperm capacitation 1 IEA Homo_sapiens(9606) Process GO:0050660 enables flavin adenine dinucleotide binding 1 IBA Homo_sapiens(9606) Function GO:0106077 involved_in histone succinylation 1 IDA Homo_sapiens(9606) Process GO:1902493 part_of acetyltransferase complex 1 IEA Homo_sapiens(9606) Component
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