Functions and Diseases

RBP Type Canonical_RBPs
Diseases CancerCHIKVSARS-COV-OC43FlavivirusesHIVRVSARS-COV-2DengueZika
Drug N.A.
Main interacting RNAs diverse
Moonlighting functions N.A.
Localizations Stress granucleNucleoli
BulkPerturb-seq DataSet_01_34 DataSet_01_74

Description

Ensembl ID ENSG00000088930 Gene ID 22803 Accession 12836
Symbol XRN2 Alias NA Full Name 5'-3' exoribonuclease 2
Status Confidence Length 86495 bases Strand Plus strand
Position 20 : 21303331 - 21389825 RNA binding domain XRN_N
Summary This gene encodes a 5'-3' exonuclease that promotes transcription termination at cotranscriptional cleavage sites. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000366396 XRN_N PF03159 6.2e-102 1

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
31213387 Transcriptional Control by Premature Termination: A Forgotten Mechanism. Kinga Kamieniarz-Gdula 2019-08-01 Trends in genetics : TIG
27263052 Biogenesis and Function of Transfer RNA-Related Fragments (tRFs). Pankaj Kumar 2016-08-01 Trends in biochemical sciences
34742921 Low Cell Number Proteomic Analysis Using In-Cell Protease Digests Reveals a Robust Signature for Cell Cycle State Classification. Van Kelly 2022-01-01 Molecular & cellular proteomics : MCP
23857582 Heterogeneous nuclear ribonucleoprotein (HnRNP) K genome-wide binding survey reveals its role in regulating 3'-end RNA processing and transcription termination at the early growth response 1 (EGR1) gene through XRN2 exonuclease. Michal Mikula 2013-08-23 The Journal of biological chemistry
31727827 Cellular RNA surveillance in health and disease. L Sandra Wolin 2019-11-15 Science (New York, N.Y.)
36344846 The transcriptional terminator XRN2 and the RNA-binding protein Sam68 link alternative polyadenylation to cell cycle progression in prostate cancer. Marco Pieraccioli 2022-11-01 Nature structural & molecular biology
32011671 Full-length NF-κB repressing factor contains an XRN2 binding domain. Jana Alexandrova 2020-02-28 The Biochemical journal
28456022 Cellular DEAD-box RNA helicase DDX6 modulates interaction of miR-122 with the 5' untranslated region of hepatitis C virus RNA. M Jason Biegel 2017-07-01 Virology
31267554 Arginine methylation of the DDX5 helicase RGG/RG motif by PRMT5 regulates resolution of RNA:DNA hybrids. Y Sofiane Mersaoui 2019-08-01 The EMBO journal
30456659 MicroRNA-135a Modulates Hepatitis C Virus Genome Replication through Downregulation of Host Antiviral Factors. Catherine Sodroski 2019-04-01 Virologica Sinica
23084833 A Tetrahymena Piwi bound to mature tRNA 3' fragments activates the exonuclease Xrn2 for RNA processing in the nucleus. T Mary Couvillion 2012-11-30 Molecular cell
31363036 Hepatitis C Virus Infection Induces Hepatic Expression of NF-κB-Inducing Kinase and Lipogenesis by Downregulating miR-122. Brianna Lowey 2019-07-30 mBio
24924487 RNA-binding proteins regulate the expression of the immune activating ligand MICB. Daphna Nachmani 2014-06-13 Nature communications
37485335 Circular RNAs in hepatocellular carcinoma: biogenesis, function, and pathology. Guocheng Rao 2023-01-01 Frontiers in genetics
29669014 Eukaryotic translation initiation factor 4AII contributes to microRNA-122 regulation of hepatitis C virus replication. Shoaib Choudhary Ahmed 2018-07-06 Nucleic acids research
36008487 Observation of conformational changes that underlie the catalytic cycle of Xrn2. H Jan Overbeck 2022-10-01 Nature chemical biology

Transcripts

Name Transcript ID bp Protein Translation ID
XRN2-201 ENST00000377191 3408 950aa ENSP00000366396

Gene Model

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
48365Child Development Disorders, Pervasive2.0376000E-005-
59616Blood Pressure1.2358817E-005-
60194Blood Pressure1.2453503E-005-

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000088930homo_sapiensENSP0000037670727.922119.4805homo_sapiensENSP0000036639649.789534.7368

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000088930homo_sapiensENSP0000036639699.789599.4737nomascus_leucogenysENSNLEP0000001224399.789599.4737
ENSG00000088930homo_sapiensENSP0000036639699.789599.6842pan_paniscusENSPPAP0000002067199.789599.6842
ENSG00000088930homo_sapiensENSP0000036639699.789599.5789pongo_abeliiENSPPYP0000001202099.789599.5789
ENSG00000088930homo_sapiensENSP0000036639699.789599.6842pan_troglodytesENSPTRP0000002282399.789599.6842
ENSG00000088930homo_sapiensENSP0000036639699.789599.6842gorilla_gorillaENSGGOP0000002600899.789599.6842
ENSG00000088930homo_sapiensENSP0000036639690.842186.9474ornithorhynchus_anatinusENSOANP0000002470494.835290.7692
ENSG00000088930homo_sapiensENSP0000036639695.368491.5789sarcophilus_harrisiiENSSHAP0000004556895.670591.8691
ENSG00000088930homo_sapiensENSP0000036639651.263246notamacropus_eugeniiENSMEUP0000000791253.399147.9167
ENSG00000088930homo_sapiensENSP0000036639660.947459.7895choloepus_hoffmanniENSCHOP0000001188363.486862.2807
ENSG00000088930homo_sapiensENSP0000036639698.631697.3684dasypus_novemcinctusENSDNOP0000000146598.631697.3684
ENSG00000088930homo_sapiensENSP0000036639668.526367.2632erinaceus_europaeusENSEEUP0000000850568.961967.6907
ENSG00000088930homo_sapiensENSP0000036639685.789583.4737echinops_telfairiENSETEP0000000140885.789583.4737
ENSG00000088930homo_sapiensENSP0000036639699.263298.6316callithrix_jacchusENSCJAP0000001023299.263298.6316
ENSG00000088930homo_sapiensENSP0000036639699.789599.5789cercocebus_atysENSCATP0000003490599.789599.5789
ENSG00000088930homo_sapiensENSP0000036639699.789599.5789macaca_fascicularisENSMFAP0000003779599.789599.5789
ENSG00000088930homo_sapiensENSP0000036639699.789599.5789macaca_mulattaENSMMUP0000004543999.789599.5789
ENSG00000088930homo_sapiensENSP0000036639699.789599.4737macaca_nemestrinaENSMNEP0000003491999.789599.4737
ENSG00000088930homo_sapiensENSP0000036639699.894799.5789papio_anubisENSPANP0000001714095.281194.9799
ENSG00000088930homo_sapiensENSP0000036639698.105397.4737mandrillus_leucophaeusENSMLEP0000003556498.002197.3712
ENSG00000088930homo_sapiensENSP0000036639691.052689.3684tursiops_truncatusENSTTRP0000000864891.052689.3684
ENSG00000088930homo_sapiensENSP0000036639698.842197.8947vulpes_vulpesENSVVUP0000001653698.842197.8947
ENSG00000088930homo_sapiensENSP0000036639697.052696mus_spretusMGP_SPRETEiJ_P005718996.950695.8991
ENSG00000088930homo_sapiensENSP0000036639698.736897.6842equus_asinusENSEASP0000505542298.736897.6842
ENSG00000088930homo_sapiensENSP0000036639697.368494.5263capra_hircusENSCHIP0000000313996.253993.4443
ENSG00000088930homo_sapiensENSP0000036639698.210596.2105loxodonta_africanaENSLAFP0000001225798.210596.2105
ENSG00000088930homo_sapiensENSP0000036639699.052697.6842panthera_leoENSPLOP0000000142399.052697.6842
ENSG00000088930homo_sapiensENSP0000036639698.736897.6842ailuropoda_melanoleucaENSAMEP0000001329198.736897.6842
ENSG00000088930homo_sapiensENSP0000036639698.421195.6842bos_indicus_hybridENSBIXP0000503039198.317695.5836
ENSG00000088930homo_sapiensENSP0000036639699.052698.1053oryctolagus_cuniculusENSOCUP0000001159699.052698.1053
ENSG00000088930homo_sapiensENSP0000036639698.842197.6842equus_caballusENSECAP0000001696897.507896.3655
ENSG00000088930homo_sapiensENSP0000036639698.842197.7895canis_lupus_familiarisENSCAFP0084503826398.842197.7895
ENSG00000088930homo_sapiensENSP0000036639699.052697.6842panthera_pardusENSPPRP0000001646199.052697.6842
ENSG00000088930homo_sapiensENSP0000036639699.368498.3158marmota_marmota_marmotaENSMMMP0000000464599.368498.3158
ENSG00000088930homo_sapiensENSP0000036639697.789596.1053balaenoptera_musculusENSBMSP0001001931097.789596.1053
ENSG00000088930homo_sapiensENSP0000036639699.157997.5789cavia_porcellusENSCPOP0000000844799.157997.5789
ENSG00000088930homo_sapiensENSP0000036639699.052697.6842felis_catusENSFCAP0000000738799.052697.6842
ENSG00000088930homo_sapiensENSP0000036639696.842195.7895ursus_americanusENSUAMP0000003254496.638795.5882
ENSG00000088930homo_sapiensENSP0000036639695.157990.9474monodelphis_domesticaENSMODP0000004135392.717988.6154
ENSG00000088930homo_sapiensENSP0000036639695.789593.0526bison_bison_bisonENSBBBP0000001500998.272195.4644
ENSG00000088930homo_sapiensENSP0000036639697.789596.2105monodon_monocerosENSMMNP0001501899797.789596.2105
ENSG00000088930homo_sapiensENSP0000036639693.578992.2105sus_scrofaENSSSCP0000003362095.591494.1936
ENSG00000088930homo_sapiensENSP0000036639698.736897.1579microcebus_murinusENSMICP0000000741698.736897.1579
ENSG00000088930homo_sapiensENSP0000036639699.052697.5789octodon_degusENSODEP0000001452499.052697.5789
ENSG00000088930homo_sapiensENSP0000036639688.842186.7368octodon_degusENSODEP0000000108195.152292.8974
ENSG00000088930homo_sapiensENSP0000036639698.210597.3684jaculus_jaculusENSJJAP0000002190598.210597.3684
ENSG00000088930homo_sapiensENSP0000036639698.526396.2105ovis_aries_rambouilletENSOARP0002000569198.422796.1094
ENSG00000088930homo_sapiensENSP0000036639697.263295.2632ursus_maritimusENSUMAP0000000503094.672192.7254
ENSG00000088930homo_sapiensENSP0000036639657.263256ochotona_princepsENSOPRP0000000131558.938257.6381
ENSG00000088930homo_sapiensENSP0000036639697.789596.2105delphinapterus_leucasENSDLEP0000000695397.789596.2105
ENSG00000088930homo_sapiensENSP0000036639697.684296.2105physeter_catodonENSPCTP0000501399497.684296.2105
ENSG00000088930homo_sapiensENSP0000036639696.947495.7895mus_caroliMGP_CAROLIEiJ_P005505896.845495.6888
ENSG00000088930homo_sapiensENSP0000036639697.052696mus_musculusENSMUSP0000002892196.950695.8991
ENSG00000088930homo_sapiensENSP0000036639696.842195.6842dipodomys_ordiiENSDORP0000000508198.818597.6369
ENSG00000088930homo_sapiensENSP0000036639699.052698mustela_putorius_furoENSMPUP0000000118690.567989.6054
ENSG00000088930homo_sapiensENSP0000036639699.157998.5263aotus_nancymaaeENSANAP0000000426899.157998.5263
ENSG00000088930homo_sapiensENSP0000036639699.368498.8421saimiri_boliviensis_boliviensisENSSBOP0000000819999.368498.8421
ENSG00000088930homo_sapiensENSP0000036639682.526380.6316vicugna_pacosENSVPAP0000000996285.124983.1705
ENSG00000088930homo_sapiensENSP0000036639699.789599.5789chlorocebus_sabaeusENSCSAP0000000730399.789599.5789
ENSG00000088930homo_sapiensENSP0000036639698.421197.0526tupaia_belangeriENSTBEP0000000360498.524897.1549
ENSG00000088930homo_sapiensENSP0000036639697.789596.8421mesocricetus_auratusENSMAUP0000002524597.995897.0464
ENSG00000088930homo_sapiensENSP0000036639697.789596.2105phocoena_sinusENSPSNP0000000661197.789596.2105
ENSG00000088930homo_sapiensENSP0000036639697.578995.1579camelus_dromedariusENSCDRP0000502881197.681895.2582
ENSG00000088930homo_sapiensENSP0000036639699.052697.0526carlito_syrichtaENSTSYP0000000763599.15797.1549
ENSG00000088930homo_sapiensENSP0000036639696.631695.2632panthera_tigris_altaicaENSPTIP0000001718496.733495.3635
ENSG00000088930homo_sapiensENSP0000036639698.315896.7368rattus_norvegicusENSRNOP0000001635098.212496.6351
ENSG00000088930homo_sapiensENSP0000036639698.842198.2105prolemur_simusENSPSMP0000001189398.842198.2105
ENSG00000088930homo_sapiensENSP0000036639697.684296.1053microtus_ochrogasterENSMOCP0000001251597.684296.1053
ENSG00000088930homo_sapiensENSP0000036639662.210560.3158sorex_araneusENSSARP0000000535962.539760.6349
ENSG00000088930homo_sapiensENSP0000036639697.368496.1053peromyscus_maniculatus_bairdiiENSPEMP0000000014997.368496.1053
ENSG00000088930homo_sapiensENSP0000036639692.736890bos_mutusENSBMUP0000000421898.216395.3177
ENSG00000088930homo_sapiensENSP0000036639697.052696mus_spicilegusENSMSIP0000001747696.950695.8991
ENSG00000088930homo_sapiensENSP0000036639695.894794.8421cricetulus_griseus_chok1gshdENSCGRP0000100840797.95796.8817
ENSG00000088930homo_sapiensENSP0000036639681.789580.9474pteropus_vampyrusENSPVAP0000000435181.96281.1181
ENSG00000088930homo_sapiensENSP0000036639698.947497.7895myotis_lucifugusENSMLUP0000000141199.051697.8925
ENSG00000088930homo_sapiensENSP0000036639691.263286.9474vombatus_ursinusENSVURP0001000714694.961790.471
ENSG00000088930homo_sapiensENSP0000036639699.263298.3158rhinolophus_ferrumequinumENSRFEP0001001483399.263298.3158
ENSG00000088930homo_sapiensENSP0000036639699.052697.8947neovison_visonENSNVIP0000003165899.052697.8947
ENSG00000088930homo_sapiensENSP0000036639698.421195.6842bos_taurusENSBTAP0000001501998.317695.5836
ENSG00000088930homo_sapiensENSP0000036639695.157993.3684heterocephalus_glaber_femaleENSHGLP0000003073590.945789.2354
ENSG00000088930homo_sapiensENSP000003663968685.7895rhinopithecus_bietiENSRBIP0000002458610099.7552
ENSG00000088930homo_sapiensENSP0000036639698.842197.7895canis_lupus_dingoENSCAFP0002003548898.842197.7895
ENSG00000088930homo_sapiensENSP0000036639699.157998.1053sciurus_vulgarisENSSVLP0000500050899.157998.1053
ENSG00000088930homo_sapiensENSP0000036639693.684289.6842phascolarctos_cinereusENSPCIP0000003304195.493691.4163
ENSG00000088930homo_sapiensENSP0000036639692.947491.2632procavia_capensisENSPCAP0000001056092.947491.2632
ENSG00000088930homo_sapiensENSP0000036639698.315897.3684nannospalax_galiliENSNGAP0000001784198.315897.3684
ENSG00000088930homo_sapiensENSP0000036639698.421195.6842bos_grunniensENSBGRP0000001079398.317695.5836
ENSG00000088930homo_sapiensENSP0000036639699.263297.8947chinchilla_lanigeraENSCLAP0000001955799.263297.8947
ENSG00000088930homo_sapiensENSP0000036639698.210596.1053cervus_hanglu_yarkandensisENSCHYP0000003403694.147392.1292
ENSG00000088930homo_sapiensENSP0000036639697.894796.3158catagonus_wagneriENSCWAP0000001052597.894796.3158
ENSG00000088930homo_sapiensENSP0000036639699.368498.3158ictidomys_tridecemlineatusENSSTOP0000000053999.368498.3158
ENSG00000088930homo_sapiensENSP0000036639698.736897.3684otolemur_garnettiiENSOGAP0000000095498.63397.266
ENSG00000088930homo_sapiensENSP0000036639638.631638.4211cebus_imitatorENSCCAP0000003809099.189298.6487
ENSG00000088930homo_sapiensENSP0000036639699.263298.3158urocitellus_parryiiENSUPAP0001001194299.263298.3158
ENSG00000088930homo_sapiensENSP0000036639698.105395.5789moschus_moschiferusENSMMSP0000002534094.046491.6246
ENSG00000088930homo_sapiensENSP0000036639698.210597.5789rhinopithecus_roxellanaENSRROP0000004253787.770587.206
ENSG00000088930homo_sapiensENSP0000036639696.947495.7895mus_pahariMGP_PahariEiJ_P006604096.845495.6888
ENSG00000088930homo_sapiensENSP0000036639691.789590.7368propithecus_coquereliENSPCOP0000001006798.978497.8434
ENSG00000088930homo_sapiensENSP0000036639659.789547.7895caenorhabditis_elegansY48B6A.3.158.256446.5641
ENSG00000088930homo_sapiensENSP0000036639657.263246.7368drosophila_melanogasterFBpp007897359.911948.8987
ENSG00000088930homo_sapiensENSP0000036639661.052648.9474ciona_intestinalisENSCINP0000003265469.711555.8894
ENSG00000088930homo_sapiensENSP0000036639630.526327.2632petromyzon_marinusENSPMAP0000000281685.545776.4012
ENSG00000088930homo_sapiensENSP0000036639671.052661.2632eptatretus_burgeriENSEBUP0000002626982.216870.8892
ENSG00000088930homo_sapiensENSP0000036639682.210570.7368callorhinchus_miliiENSCMIP0000004532682.037870.5882
ENSG00000088930homo_sapiensENSP0000036639678.947470.9474latimeria_chalumnaeENSLACP0000000941881.433273.1813
ENSG00000088930homo_sapiensENSP0000036639682.631672.2105lepisosteus_oculatusENSLOCP0000002086383.156872.6695
ENSG00000088930homo_sapiensENSP0000036639680.105369.5789clupea_harengusENSCHAP0000002526777.337467.1748
ENSG00000088930homo_sapiensENSP0000036639680.526370.3158danio_rerioENSDARP0000013885080.357170.1681
ENSG00000088930homo_sapiensENSP0000036639677.368468.7368carassius_auratusENSCARP0000009661076.963368.377
ENSG00000088930homo_sapiensENSP0000036639679.052668.9474carassius_auratusENSCARP0000010310077.342967.4562
ENSG00000088930homo_sapiensENSP0000036639680.105370.4211astyanax_mexicanusENSAMXP0000004003476.176266.967
ENSG00000088930homo_sapiensENSP0000036639680.842170.6316ictalurus_punctatusENSIPUP0000000968779.585569.5337
ENSG00000088930homo_sapiensENSP0000036639682.105371.5789esox_luciusENSELUP0000001530179.429769.2464
ENSG00000088930homo_sapiensENSP0000036639681.052671.5789electrophorus_electricusENSEEEP0000001960979.218169.9588
ENSG00000088930homo_sapiensENSP0000036639679.684269.2632oncorhynchus_kisutchENSOKIP0000500808178.608568.3281
ENSG00000088930homo_sapiensENSP0000036639675.263265.0526oncorhynchus_kisutchENSOKIP0000509666479.268368.5144
ENSG00000088930homo_sapiensENSP0000036639680.631669.8947oncorhynchus_mykissENSOMYP0000013887380.209469.5288
ENSG00000088930homo_sapiensENSP000003663968069.5789oncorhynchus_mykissENSOMYP0000009863778.674968.4265
ENSG00000088930homo_sapiensENSP0000036639680.105369.4737salmo_salarENSSSAP0000014275579.353568.8217
ENSG00000088930homo_sapiensENSP0000036639678.947468.3158salmo_salarENSSSAP0000010518579.533468.8229
ENSG00000088930homo_sapiensENSP0000036639680.842170.1053salmo_truttaENSSTUP0000006029080.16769.5198
ENSG00000088930homo_sapiensENSP0000036639680.210569.7895salmo_truttaENSSTUP0000007694979.623869.279
ENSG00000088930homo_sapiensENSP0000036639677.368467.0526gadus_morhuaENSGMOP0000002376171.359261.8447
ENSG00000088930homo_sapiensENSP0000036639624.947419.7895fundulus_heteroclitusENSFHEP0000002865545.664736.2235
ENSG00000088930homo_sapiensENSP0000036639643.578938.3158fundulus_heteroclitusENSFHEP0000001154681.496171.6535
ENSG00000088930homo_sapiensENSP0000036639678.315868.5263poecilia_reticulataENSPREP0000001838778.897169.035
ENSG00000088930homo_sapiensENSP0000036639680.947470.1053xiphophorus_maculatusENSXMAP0000000025979.524368.8728
ENSG00000088930homo_sapiensENSP0000036639679.578970.1053oryzias_latipesENSORLP0000002154777.777868.5185
ENSG00000088930homo_sapiensENSP0000036639677.368467.7895cyclopterus_lumpusENSCLMP0000502378871.567762.7069
ENSG00000088930homo_sapiensENSP0000036639677.578968.2105oreochromis_niloticusENSONIP0000002356779.934970.282
ENSG00000088930homo_sapiensENSP0000036639646.842141.2632haplochromis_burtoniENSHBUP0000002393982.560372.7273
ENSG00000088930homo_sapiensENSP0000036639676.421167.5789astatotilapia_callipteraENSACLP0000001559482.312972.7891
ENSG00000088930homo_sapiensENSP0000036639680.947470.6316sparus_aurataENSSAUP0001004364179.196769.104
ENSG00000088930homo_sapiensENSP0000036639680.842170.4211lates_calcariferENSLCAP0001005387378.367368.2653
ENSG00000088930homo_sapiensENSP0000036639682.210572.8421xenopus_tropicalisENSXETP0000006637183.440273.9316
ENSG00000088930homo_sapiensENSP0000036639690.842184.5263chrysemys_picta_belliiENSCPBP0000003367790.083583.8205
ENSG00000088930homo_sapiensENSP0000036639684.736877.8947sphenodon_punctatusENSSPUP0000000713785.185278.3069
ENSG00000088930homo_sapiensENSP0000036639681.052673.8947crocodylus_porosusENSCPRP0000501559885.650778.0868
ENSG00000088930homo_sapiensENSP0000036639662.210556.5263laticauda_laticaudataENSLLTP0000002400780.408273.0612
ENSG00000088930homo_sapiensENSP0000036639688.105382notechis_scutatusENSNSUP0000001451787.187581.1458
ENSG00000088930homo_sapiensENSP0000036639688.421182.3158pseudonaja_textilisENSPTXP0000000524787.581.4583
ENSG00000088930homo_sapiensENSP0000036639680.736874.1053anas_platyrhynchos_platyrhynchosENSAPLP0000001375087.958780.7339
ENSG00000088930homo_sapiensENSP0000036639688.736881.7895gallus_gallusENSGALP0001002609288.830381.8757
ENSG00000088930homo_sapiensENSP0000036639673.894768.5263meleagris_gallopavoENSMGAP0000000295992.857186.1111
ENSG00000088930homo_sapiensENSP0000036639689.578982.5263serinus_canariaENSSCAP0000002052589.673382.6133
ENSG00000088930homo_sapiensENSP0000036639689.789582.3158parus_majorENSPMJP0000001832989.884182.4025
ENSG00000088930homo_sapiensENSP0000036639685.684279.4737anolis_carolinensisENSACAP0000000555485.774579.5574
ENSG00000088930homo_sapiensENSP0000036639677.894769.2632neolamprologus_brichardiENSNBRP0000001051883.521474.2664
ENSG00000088930homo_sapiensENSP0000036639686.210579.4737naja_najaENSNNAP0000001781786.301479.5574
ENSG00000088930homo_sapiensENSP0000036639687.894780.8421podarcis_muralisENSPMRP0000003090387.434680.4188
ENSG00000088930homo_sapiensENSP000003663968477.1579geospiza_fortisENSGFOP0000001011789.16281.8994
ENSG00000088930homo_sapiensENSP0000036639689.157982.1053taeniopygia_guttataENSTGUP0000000780589.251882.1918
ENSG00000088930homo_sapiensENSP0000036639682.421173.1579erpetoichthys_calabaricusENSECRP0000000494782.334473.081
ENSG00000088930homo_sapiensENSP0000036639610.10539.36842kryptolebias_marmoratusENSKMAP000000027189689
ENSG00000088930homo_sapiensENSP0000036639687.368479.8947salvator_merianaeENSSMRP0000002176787.184979.7269
ENSG00000088930homo_sapiensENSP0000036639680.210570.4211oryzias_javanicusENSOJAP0000003382577.834568.335
ENSG00000088930homo_sapiensENSP0000036639674.631665.0526amphilophus_citrinellusENSACIP0000001943976.565966.7387
ENSG00000088930homo_sapiensENSP0000036639680.947471.4737dicentrarchus_labraxENSDLAP0000503010979.196769.9279
ENSG00000088930homo_sapiensENSP0000036639681.052670.8421amphiprion_perculaENSAPEP0000002082379.136769.1675
ENSG00000088930homo_sapiensENSP0000036639679.684270.4211oryzias_sinensisENSOSIP0000003726477.880768.8272
ENSG00000088930homo_sapiensENSP0000036639675.894770.2105pelodiscus_sinensisENSPSIP0000001645693.880286.849
ENSG00000088930homo_sapiensENSP0000036639690.842184.4211gopherus_evgoodeiENSGEVP0000502409490.083583.7161
ENSG00000088930homo_sapiensENSP0000036639691.052684.2105chelonoidis_abingdoniiENSCABP0000002788090.292383.5073
ENSG00000088930homo_sapiensENSP0000036639674.421165.3684seriola_dumeriliENSSDUP0000001775580.432370.6485
ENSG00000088930homo_sapiensENSP0000036639680.315869.8947cottoperca_gobioENSCGOP0000004084678.176268.0328
ENSG00000088930homo_sapiensENSP0000036639681.684274.3158struthio_camelus_australisENSSCUP0000000911887.387479.5045
ENSG00000088930homo_sapiensENSP0000036639689.368482.6316anser_brachyrhynchusENSABRP0000001280289.462682.7187
ENSG00000088930homo_sapiensENSP0000036639673.052664.8421gasterosteus_aculeatusENSGACP0000001571085.997576.3321
ENSG00000088930homo_sapiensENSP0000036639643.473738.8421cynoglossus_semilaevisENSCSEP0000000880083.266174.3952
ENSG00000088930homo_sapiensENSP0000036639620.842117.2632cynoglossus_semilaevisENSCSEP0000000880663.258852.3962
ENSG00000088930homo_sapiensENSP0000036639681.052670.8421poecilia_formosaENSPFOP0000000450979.627769.5967
ENSG00000088930homo_sapiensENSP0000036639676.631667.7895myripristis_murdjanENSMMDP0000502329482.259972.7684
ENSG00000088930homo_sapiensENSP0000036639679.789570.2105sander_luciopercaENSSLUP0000003584277.823468.4805
ENSG00000088930homo_sapiensENSP000003663969083.3684strigops_habroptilaENSSHBP000050048499083.3684
ENSG00000088930homo_sapiensENSP0000036639680.947470.8421amphiprion_ocellarisENSAOCP0000001843879.115269.2387
ENSG00000088930homo_sapiensENSP0000036639691.052684.4211terrapene_carolina_triunguisENSTMTP0000001801290.292383.7161
ENSG00000088930homo_sapiensENSP0000036639680.842170.1053hucho_huchoENSHHUP0000004008980.757170.0315
ENSG00000088930homo_sapiensENSP0000036639679.894769.2632hucho_huchoENSHHUP0000008034478.652868.1865
ENSG00000088930homo_sapiensENSP0000036639679.263269.1579betta_splendensENSBSLP0000002107476.446766.7005
ENSG00000088930homo_sapiensENSP0000036639681.578971.8947pygocentrus_nattereriENSPNAP0000000452179.650670.1953
ENSG00000088930homo_sapiensENSP0000036639681.157970.3158anabas_testudineusENSATEP0000006465079.076968.5128
ENSG00000088930homo_sapiensENSP0000036639663.894751.1579ciona_savignyiENSCSAVP0000001910667.220453.8206
ENSG00000088930homo_sapiensENSP0000036639651.894736.3158saccharomyces_cerevisiaeYOR048C49.00634.2942
ENSG00000088930homo_sapiensENSP0000036639677.052667.5789seriola_lalandi_dorsalisENSSLDP0000002740982.339772.216
ENSG00000088930homo_sapiensENSP0000036639647.473742.4211labrus_bergyltaENSLBEP0000001311789.66280.1193
ENSG00000088930homo_sapiensENSP0000036639622.631619.4737labrus_bergyltaENSLBEP0000003080174.652864.2361
ENSG00000088930homo_sapiensENSP0000036639676.421167.5789pundamilia_nyerereiENSPNYP0000000239082.312972.7891
ENSG00000088930homo_sapiensENSP0000036639680.842170.2105mastacembelus_armatusENSMAMP0000004201579.093768.6921
ENSG00000088930homo_sapiensENSP0000036639680.526370.7368stegastes_partitusENSSPAP0000002125878.784869.207
ENSG00000088930homo_sapiensENSP0000036639680.526369.6842oncorhynchus_tshawytschaENSOTSP0000504198080.357169.5378
ENSG00000088930homo_sapiensENSP0000036639679.578969.0526oncorhynchus_tshawytschaENSOTSP0000508540278.832168.4046
ENSG00000088930homo_sapiensENSP0000036639681.052670.4211acanthochromis_polyacanthusENSAPOP0000002619579.218168.8272
ENSG00000088930homo_sapiensENSP0000036639688.526382aquila_chrysaetos_chrysaetosENSACCP0002000899389.754583.1377
ENSG00000088930homo_sapiensENSP0000036639679.157969.6842nothobranchius_furzeriENSNFUP0001502961579.408769.905
ENSG00000088930homo_sapiensENSP0000036639674.947465.7895cyprinodon_variegatusENSCVAP0000001596680.634270.7814
ENSG00000088930homo_sapiensENSP0000036639679.263268.2105denticeps_clupeoidesENSDCDP0000000843877.628966.8041
ENSG00000088930homo_sapiensENSP0000036639680.105370.1053larimichthys_croceaENSLCRP0000505846477.258967.6142
ENSG00000088930homo_sapiensENSP0000036639678.315867.7895takifugu_rubripesENSTRUP0000008455175.151565.0505
ENSG00000088930homo_sapiensENSP0000036639684.105377.1579ficedula_albicollisENSFALP0000001649980.140473.5206
ENSG00000088930homo_sapiensENSP0000036639678.421169.3684hippocampus_comesENSHCOP0000000951076.175967.3824
ENSG00000088930homo_sapiensENSP0000036639680.631671.1579cyprinus_carpio_carpioENSCCRP0000011169679.958270.5637
ENSG00000088930homo_sapiensENSP000003663967868.8421cyprinus_carpio_carpioENSCCRP0000008097077.187568.125
ENSG00000088930homo_sapiensENSP0000036639681.052674.5263coturnix_japonicaENSCJPP0000501948188.201681.0997
ENSG00000088930homo_sapiensENSP0000036639677.473768.1053poecilia_latipinnaENSPLAP0000000543982.511272.5336
ENSG00000088930homo_sapiensENSP0000036639680.105370.9474sinocyclocheilus_grahamiENSSGRP0000000244779.436370.3549
ENSG00000088930homo_sapiensENSP0000036639680.105370.1053sinocyclocheilus_grahamiENSSGRP0000005392779.769469.8113
ENSG00000088930homo_sapiensENSP0000036639677.684269.2632maylandia_zebraENSMZEP0000502999283.201874.1826
ENSG00000088930homo_sapiensENSP0000036639680.421170.9474tetraodon_nigroviridisENSTNIP0000001363080.336570.8728
ENSG00000088930homo_sapiensENSP0000036639679.684269.5789paramormyrops_kingsleyaeENSPKIP0000003959476.54266.8352
ENSG00000088930homo_sapiensENSP0000036639678.315869.4737scleropages_formosusENSSFOP0001500173582.300973.0089
ENSG00000088930homo_sapiensENSP0000036639682.947473.5789leptobrachium_leishanenseENSLLEP0000002519784.278174.7594
ENSG00000088930homo_sapiensENSP0000036639679.894769.0526scophthalmus_maximusENSSMAP0000007060577.846267.2821
ENSG00000088930homo_sapiensENSP0000036639677.684268.3158oryzias_melastigmaENSOMEP0000003368068.20759.9815

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0000175enables 3-5-RNA exonuclease activity1EXPHomo_sapiens(9606)Function
GO:0000956involved_in nuclear-transcribed mRNA catabolic process1IBAHomo_sapiens(9606)Process
GO:0001147enables transcription termination site sequence-specific DNA binding1IDAHomo_sapiens(9606)Function
GO:0003723enables RNA binding2HDA,IBAHomo_sapiens(9606)Function
GO:0004518enables nuclease activity1TASHomo_sapiens(9606)Function
GO:0004534enables 5-3 RNA exonuclease activity2IBA,TASHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005634is_active_in nucleus1IBAHomo_sapiens(9606)Component
GO:0005654located_in nucleoplasm2IDA,TASHomo_sapiens(9606)Component
GO:0005730located_in nucleolus1IDAHomo_sapiens(9606)Component
GO:0006364involved_in rRNA processing1TASHomo_sapiens(9606)Process
GO:0006369involved_in termination of RNA polymerase II transcription1IMPHomo_sapiens(9606)Process
GO:0006396involved_in RNA processing1TASHomo_sapiens(9606)Process
GO:0006397involved_in mRNA processing1IEAHomo_sapiens(9606)Process
GO:0006401involved_in RNA catabolic process1TASHomo_sapiens(9606)Process
GO:0007283involved_in spermatogenesis1IEPHomo_sapiens(9606)Process
GO:0008409enables 5-3 exonuclease activity1IDAHomo_sapiens(9606)Function
GO:0016020located_in membrane1HDAHomo_sapiens(9606)Component
GO:0016070involved_in RNA metabolic process1ISSHomo_sapiens(9606)Process
GO:0016235located_in aggresome1IDAHomo_sapiens(9606)Component
GO:0021766involved_in hippocampus development1IEAHomo_sapiens(9606)Process
GO:0030182involved_in neuron differentiation1IEAHomo_sapiens(9606)Process
GO:0042802enables identical protein binding1IPIHomo_sapiens(9606)Function
GO:0046872enables metal ion binding1IEAHomo_sapiens(9606)Function
GO:0060041involved_in retina development in camera-type eye1IEAHomo_sapiens(9606)Process

Expression