Ensembl ID ENSG00000088930 Gene ID 22803 Accession 12836
Gene Symbol XRN2 Alias NA Full Name 5'-3' exoribonuclease 2
Position 20 : 21303331 - 21389825 Length 86495 bases Strand Plus strand
Status Confidence Main interacting RNAsdiverseRBP type Canonical_RBPs
Summary This gene encodes a 5'-3' exonuclease that promotes transcription termination at cotranscriptional cleavage sites. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015]

ENSG00000088930 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000088930 XRN2 0.61 3.25e-12 COAD
ENSG00000088930 XRN2 1.39 4.52e-15 GBM
ENSG00000088930 XRN2 0.69 1.30e-13 STAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000088930 XRN2 lung cancer 19915612
ENSG00000088930 XRN2 tumor 26531822
ENSG00000088930 XRN2 lung cancer 28319071
ENSG00000088930 XRN2 cancer 31519929
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000088930 XRN2 MESO 0.013 high
ENSG00000088930 XRN2 SARC 0.0055 high
ENSG00000088930 XRN2 UVM 0.022 high
ENSG00000088930 XRN2 PAAD 0.0093 high
ENSG00000088930 XRN2 UCEC 0.026 high
ENSG00000088930 XRN2 THCA 0.012 high
ENSG00000088930 XRN2 LUSC 0.0085 high
ENSG00000088930 XRN2 PCPG 0.05 low
ENSG00000088930 XRN2 ESCA 0.027 high
ENSG00000088930 XRN2 BLCA 0.032 high
ENSG00000088930 XRN2 GBM 0.011 low
ENSG00000088930 XRN2 CESC 0.004 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000088930 XRN2 READ Amp 0.901645 0.134955 0.946266 0.606061
ENSG00000088930 XRN2 COAD Amp 2.495876 0.101071 0.870366 0.512195
ENSG00000088930 XRN2 PAAD Amp 0.651922 0.079100 0.513073 0.206522