Functions and Diseases

RBP Type Non-canonical_RBPs
Diseases Cancer Disease
Drug N.A.
Main interacting RNAs N.A.
Moonlighting functions E3 ligaseTransmemebrane
Localizations N.A.
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000086758 Gene ID 10075 Accession 30892
Symbol HUWE1 Alias MULE;Ib772;LASU1;MRXST;UREB1;HECTH9;URE-B1;ARF-BP1;HSPC272 Full Name HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1
Status Confidence Length 154624 bases Strand Minus strand
Position X : 53532096 - 53686719 RNA binding domain N.A.
Summary This gene encodes a protein containing a C-terminal HECT (E6AP type E3 ubiquitin protein ligase) domain that functions as an E3 ubiquitin ligase. The encoded protein is required for the ubiquitination and subsequent degradation of the anti-apoptotic protein Mcl1 (myeloid cell leukemia sequence 1 (BCL2-related)). This protein also ubiquitinates the p53 tumor suppressor, core histones, and DNA polymerase beta. Mutations in this gene are associated with Turner type X-linked syndromic cognitive disability. [provided by RefSeq, Aug 2013]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
24410894 Dissecting the expression landscape of RNA-binding proteins in human cancers. Bobak Kechavarzi 2014-01-10 Genome biology
36200807 DDX17 is required for efficient DSB repair at DNA:RNA hybrid deficient loci. S Aldo Bader 2022-10-14 Nucleic acids research

Transcripts

Name Transcript ID bp Protein Translation ID
HUWE1-204 ENST00000426907 4805 1197aa ENSP00000403236
HUWE1-214 ENST00000612484 14311 4365aa ENSP00000479451
HUWE1-203 ENST00000342160 14796 4374aa ENSP00000340648
HUWE1-202 ENST00000262854 14731 4374aa ENSP00000262854
HUWE1-216 ENST00000704099 14522 4302aa ENSP00000515693
HUWE1-212 ENST00000488459 800 No protein -
HUWE1-210 ENST00000474971 598 No protein -
HUWE1-211 ENST00000480438 564 No protein -
HUWE1-206 ENST00000463852 586 No protein -
HUWE1-207 ENST00000468322 729 191aa ENSP00000483891
HUWE1-209 ENST00000474288 1254 No protein -
HUWE1-201 ENST00000218328 5488 No protein -
HUWE1-213 ENST00000489876 754 No protein -
HUWE1-217 ENST00000704100 1829 557aa ENSP00000515694
HUWE1-215 ENST00000622887 688 230aa ENSP00000484417
HUWE1-208 ENST00000471676 501 No protein -
HUWE1-218 ENST00000704101 759 142aa ENSP00000515695
HUWE1-205 ENST00000446750 872 92aa ENSP00000413651
HUWE1-219 ENST00000704102 507 No protein -

Gene Model

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000086758homo_sapiensENSP0000034059632.958818.3521homo_sapiensENSP000002628548.047554.48102
ENSG00000086758homo_sapiensENSP0000036280432.125817.7312homo_sapiensENSP000002628547.704624.2524
ENSG00000086758homo_sapiensENSP0000038568433.333317.7143homo_sapiensENSP000002628548.001834.2524
ENSG00000086758homo_sapiensENSP0000049541835.241720.8015homo_sapiensENSP0000026285412.66587.47599
ENSG00000086758homo_sapiensENSP0000036399853.480332.5986homo_sapiensENSP0000026285410.53966.42433
ENSG00000086758homo_sapiensENSP0000035532653.76235.4309homo_sapiensENSP000002628548.984915.92135
ENSG00000086758homo_sapiensENSP0000050271322.109311.6594homo_sapiensENSP0000026285410.44815.50983
ENSG00000086758homo_sapiensENSP0000026434631.40917.0254homo_sapiensENSP000002628547.338823.97805
ENSG00000086758homo_sapiensENSP0000029806839.819623.7113homo_sapiensENSP000002628547.064474.20668
ENSG00000086758homo_sapiensENSP0000026160910.75715.89574homo_sapiensENSP0000026285411.88846.51578
ENSG00000086758homo_sapiensENSP0000037922835.05620.4234homo_sapiensENSP0000026285412.87157.49886
ENSG00000086758homo_sapiensENSP0000034871437.545621.7497homo_sapiensENSP000002628547.064474.09236
ENSG00000086758homo_sapiensENSP0000041061353.444436.2222homo_sapiensENSP0000026285410.99687.45313
ENSG00000086758homo_sapiensENSP0000030919837.211420.4986homo_sapiensENSP000002628549.213535.07545
ENSG00000086758homo_sapiensENSP0000042779352.494633.1887homo_sapiensENSP0000026285411.06546.99588
ENSG00000086758homo_sapiensENSP0000050768718.46999.95926homo_sapiensENSP0000026285418.655710.0594
ENSG00000086758homo_sapiensENSP0000038226919.15719.50192homo_sapiensENSP0000026285411.43125.66987
ENSG00000086758homo_sapiensENSP0000038319952.102634.359homo_sapiensENSP0000026285411.61417.65889
ENSG00000086758homo_sapiensENSP0000026435030.859417.2852homo_sapiensENSP000002628547.224514.04664
ENSG00000086758homo_sapiensENSP0000026243553.743336.8984homo_sapiensENSP000002628549.190676.31001
ENSG00000086758homo_sapiensENSP0000049757240.596322.2477homo_sapiensENSP000002628548.093284.4353
ENSG00000086758homo_sapiensENSP0000026290341.034126.4026homo_sapiensENSP000002628548.527665.48697
ENSG00000086758homo_sapiensENSP0000035206953.103433.2184homo_sapiensENSP0000026285410.56246.60722
ENSG00000086758homo_sapiensENSP0000042908423.901413.3262homo_sapiensENSP0000026285415.29498.52766

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000086758homo_sapiensENSP0000026285498.33198.2167nomascus_leucogenysENSNLEP0000004910598.241298.127
ENSG00000086758homo_sapiensENSP0000026285498.994198.834pan_paniscusENSPPAP0000001536298.141497.9828
ENSG00000086758homo_sapiensENSP0000026285499.794299.7485pongo_abeliiENSPPYP0000002280999.794299.7485
ENSG00000086758homo_sapiensENSP0000026285498.994198.834pan_troglodytesENSPTRP0000006674198.141497.9828
ENSG00000086758homo_sapiensENSP0000026285498.765498.5597gorilla_gorillaENSGGOP0000004056298.181897.9773
ENSG00000086758homo_sapiensENSP0000026285495.656292.9584ornithorhynchus_anatinusENSOANP0000000112896.051493.3425
ENSG00000086758homo_sapiensENSP0000026285488.614584.9794sarcophilus_harrisiiENSSHAP0000000123091.287.4588
ENSG00000086758homo_sapiensENSP0000026285479.629676.2917notamacropus_eugeniiENSMEUP0000001082287.954584.2677
ENSG00000086758homo_sapiensENSP0000026285447.782346.4106choloepus_hoffmanniENSCHOP0000000018566.370364.4649
ENSG00000086758homo_sapiensENSP0000026285494.695993.5071dasypus_novemcinctusENSDNOP0000001172896.505195.2936
ENSG00000086758homo_sapiensENSP0000026285489.917789.209erinaceus_europaeusENSEEUP0000000032490.144489.4339
ENSG00000086758homo_sapiensENSP0000026285473.616872.9081echinops_telfairiENSETEP0000000365474.65873.9393
ENSG00000086758homo_sapiensENSP0000026285499.291398.9941callithrix_jacchusENSCJAP0000001150299.336799.0393
ENSG00000086758homo_sapiensENSP0000026285498.765498.5597cercocebus_atysENSCATP0000002357498.383198.1781
ENSG00000086758homo_sapiensENSP0000026285499.428499.3141macaca_fascicularisENSMFAP0000000094599.405799.2914
ENSG00000086758homo_sapiensENSP0000026285499.748599.6342macaca_mulattaENSMMUP0000000839799.748599.6342
ENSG00000086758homo_sapiensENSP0000026285498.719798.5597macaca_nemestrinaENSMNEP0000001156498.270498.1111
ENSG00000086758homo_sapiensENSP0000026285499.108498.8569papio_anubisENSPANP0000000516298.232597.9832
ENSG00000086758homo_sapiensENSP0000026285498.399698.171mandrillus_leucophaeusENSMLEP0000003390398.197697.9694
ENSG00000086758homo_sapiensENSP0000026285492.821292.2725tursiops_truncatusENSTTRP0000000007993.183492.6325
ENSG00000086758homo_sapiensENSP0000026285498.994198.6054vulpes_vulpesENSVVUP0000004199298.030397.6455
ENSG00000086758homo_sapiensENSP0000026285498.628397.8281mus_spretusMGP_SPRETEiJ_P009682298.538197.7387
ENSG00000086758homo_sapiensENSP0000026285499.016998.6511equus_asinusENSEASP0000502594398.05397.6907
ENSG00000086758homo_sapiensENSP0000026285497.736697.0279capra_hircusENSCHIP0000002304698.366397.653
ENSG00000086758homo_sapiensENSP0000026285498.719798.0796loxodonta_africanaENSLAFP0000001239198.764998.1244
ENSG00000086758homo_sapiensENSP0000026285498.879798.4454panthera_leoENSPLOP0000002752498.92598.4904
ENSG00000086758homo_sapiensENSP0000026285499.222798.8112ailuropoda_melanoleucaENSAMEP0000000530999.298.7886
ENSG00000086758homo_sapiensENSP0000026285494.673193.5757bos_indicus_hybridENSBIXP0000503245993.244892.1639
ENSG00000086758homo_sapiensENSP0000026285497.828197.1193oryctolagus_cuniculusENSOCUP0000000637398.84598.1289
ENSG00000086758homo_sapiensENSP0000026285498.994198.6283equus_caballusENSECAP0000003777697.764797.4035
ENSG00000086758homo_sapiensENSP0000026285498.513998.1253canis_lupus_familiarisENSCAFP0084504085899.125898.7348
ENSG00000086758homo_sapiensENSP0000026285498.902698.4682panthera_pardusENSPPRP0000001708498.947998.5133
ENSG00000086758homo_sapiensENSP0000026285495.587695.1075marmota_marmota_marmotaENSMMMP0000001467199.240498.742
ENSG00000086758homo_sapiensENSP0000026285498.742698.2625balaenoptera_musculusENSBMSP0001002442499.105198.6232
ENSG00000086758homo_sapiensENSP0000026285497.210896.5706cavia_porcellusENSCPOP0000000453998.471597.8231
ENSG00000086758homo_sapiensENSP0000026285499.016998.6054felis_catusENSFCAP0000000642399.016998.6054
ENSG00000086758homo_sapiensENSP0000026285498.994198.5825ursus_americanusENSUAMP0000003084797.897497.4904
ENSG00000086758homo_sapiensENSP0000026285494.375991.1294monodelphis_domesticaENSMODP0000002612194.289691.0461
ENSG00000086758homo_sapiensENSP000002628543.726573.56653bison_bison_bisonENSBBBP0000002758792.613688.6364
ENSG00000086758homo_sapiensENSP0000026285498.742698.2396monodon_monocerosENSMMNP0001502091299.105198.6003
ENSG00000086758homo_sapiensENSP0000026285499.291398.9026sus_scrofaENSSSCP0000001312098.369297.9841
ENSG00000086758homo_sapiensENSP0000026285497.34896.845microcebus_murinusENSMICP0000002713797.459496.9558
ENSG00000086758homo_sapiensENSP0000026285498.513997.8738octodon_degusENSODEP0000001369298.423997.7844
ENSG00000086758homo_sapiensENSP0000026285498.513997.7138jaculus_jaculusENSJJAP0000001367798.446497.6468
ENSG00000086758homo_sapiensENSP0000026285494.673193.6671ovis_aries_rambouilletENSOARP0002000868393.181892.1917
ENSG00000086758homo_sapiensENSP0000026285498.811298.3082ursus_maritimusENSUMAP0000003141597.782897.2851
ENSG00000086758homo_sapiensENSP0000026285452.354851.9433ochotona_princepsENSOPRP0000000038352.462852.0504
ENSG00000086758homo_sapiensENSP0000026285497.210896.5935delphinapterus_leucasENSDLEP0000002239097.055596.4392
ENSG00000086758homo_sapiensENSP0000026285498.879798.4682physeter_catodonENSPCTP0000502329799.197398.7844
ENSG00000086758homo_sapiensENSP0000026285498.559797.7366mus_caroliMGP_CAROLIEiJ_P009305998.469697.6473
ENSG00000086758homo_sapiensENSP0000026285498.628397.8281mus_musculusENSMUSP0000002629298.538197.7387
ENSG00000086758homo_sapiensENSP0000026285498.216797.0965dipodomys_ordiiENSDORP0000000930798.239297.1187
ENSG00000086758homo_sapiensENSP0000026285498.285397.6223mustela_putorius_furoENSMPUP0000000968698.21897.5554
ENSG00000086758homo_sapiensENSP0000026285498.948398.5825aotus_nancymaaeENSANAP0000002370398.296697.9332
ENSG00000086758homo_sapiensENSP0000026285496.524995.8848saimiri_boliviensis_boliviensisENSSBOP0000000736896.94696.3031
ENSG00000086758homo_sapiensENSP0000026285482.487482.2131vicugna_pacosENSVPAP0000000300185.477485.1931
ENSG00000086758homo_sapiensENSP0000026285499.725799.6113chlorocebus_sabaeusENSCSAP0000000870699.725799.6113
ENSG00000086758homo_sapiensENSP0000026285481.89381.4129tupaia_belangeriENSTBEP0000000498981.96881.4874
ENSG00000086758homo_sapiensENSP0000026285497.416596.2048mesocricetus_auratusENSMAUP0000001675497.90996.6912
ENSG00000086758homo_sapiensENSP0000026285498.811298.2853phocoena_sinusENSPSNP0000002283999.128498.6009
ENSG00000086758homo_sapiensENSP0000026285498.811298.3768camelus_dromedariusENSCDRP0000503021699.128498.6927
ENSG00000086758homo_sapiensENSP0000026285475.308674.6914carlito_syrichtaENSTSYP0000000226896.513395.7222
ENSG00000086758homo_sapiensENSP0000026285497.439496.9364panthera_tigris_altaicaENSPTIP0000000889098.202897.6959
ENSG00000086758homo_sapiensENSP0000026285498.628397.8052rattus_norvegicusENSRNOP0000009512996.856896.0485
ENSG00000086758homo_sapiensENSP0000026285498.399697.7138prolemur_simusENSPSMP0000002619298.354797.6691
ENSG00000086758homo_sapiensENSP0000026285498.399697.5537microtus_ochrogasterENSMOCP0000000952698.602597.7549
ENSG00000086758homo_sapiensENSP0000026285490.169289.4376sorex_araneusENSSARP0000000960590.562689.8278
ENSG00000086758homo_sapiensENSP0000026285498.83498.0567peromyscus_maniculatus_bairdiiENSPEMP0000000500898.83498.0567
ENSG00000086758homo_sapiensENSP0000026285498.765498.1253bos_mutusENSBMUP0000002614998.833298.1926
ENSG00000086758homo_sapiensENSP0000026285498.582597.8052mus_spicilegusENSMSIP0000000624698.51597.7382
ENSG00000086758homo_sapiensENSP0000026285498.651197.8281cricetulus_griseus_chok1gshdENSCGRP0000101596398.673797.8504
ENSG00000086758homo_sapiensENSP0000026285496.524995.9534pteropus_vampyrusENSPVAP0000000681696.480895.9095
ENSG00000086758homo_sapiensENSP0000026285498.056797.3708myotis_lucifugusENSMLUP0000000019698.056797.3708
ENSG00000086758homo_sapiensENSP0000026285468.198465.6836vombatus_ursinusENSVURP0001002613593.393989.9499
ENSG00000086758homo_sapiensENSP0000026285499.131298.5597rhinolophus_ferrumequinumENSRFEP0001000308099.108698.5371
ENSG00000086758homo_sapiensENSP0000026285499.062698.6283neovison_visonENSNVIP0000003027299.017498.5832
ENSG00000086758homo_sapiensENSP0000026285498.925598.2625bos_taurusENSBTAP0000000806098.902998.24
ENSG00000086758homo_sapiensENSP0000026285498.67498.0796heterocephalus_glaber_femaleENSHGLP0000000334998.719198.1244
ENSG00000086758homo_sapiensENSP0000026285493.804393.5071rhinopithecus_bietiENSRBIP0000002090198.843798.5305
ENSG00000086758homo_sapiensENSP0000026285498.308297.8052canis_lupus_dingoENSCAFP0002002513197.838597.3379
ENSG00000086758homo_sapiensENSP0000026285498.971298.4225sciurus_vulgarisENSSVLP0000501795999.334698.7838
ENSG00000086758homo_sapiensENSP0000026285481.275779.8583procavia_capensisENSPCAP0000000862081.592880.1698
ENSG00000086758homo_sapiensENSP0000026285419.067218.9758nannospalax_galiliENSNGAP0000002235892.256691.8142
ENSG00000086758homo_sapiensENSP0000026285498.879798.2396bos_grunniensENSBGRP0000004151098.902498.2621
ENSG00000086758homo_sapiensENSP0000026285498.925598.3996chinchilla_lanigeraENSCLAP0000000912198.812598.2873
ENSG00000086758homo_sapiensENSP0000026285498.948398.3082cervus_hanglu_yarkandensisENSCHYP0000002411098.948398.3082
ENSG00000086758homo_sapiensENSP0000026285499.268498.8569catagonus_wagneriENSCWAP0000000553298.324397.9167
ENSG00000086758homo_sapiensENSP0000026285499.222798.674ictidomys_tridecemlineatusENSSTOP0000002777598.234597.6913
ENSG00000086758homo_sapiensENSP0000026285498.948398.3082otolemur_garnettiiENSOGAP0000000179698.903198.2633
ENSG00000086758homo_sapiensENSP0000026285496.982296.4106cebus_imitatorENSCCAP0000001503597.137696.5651
ENSG00000086758homo_sapiensENSP0000026285498.856998.3768urocitellus_parryiiENSUPAP0001000136098.205897.7288
ENSG00000086758homo_sapiensENSP0000026285498.83498.2396moschus_moschiferusENSMMSP0000000833598.811498.2171
ENSG00000086758homo_sapiensENSP0000026285498.67498.4454rhinopithecus_roxellanaENSRROP0000001072897.580897.3547
ENSG00000086758homo_sapiensENSP0000026285498.491197.6452mus_pahariMGP_PahariEiJ_P009066898.378697.5337
ENSG00000086758homo_sapiensENSP0000026285498.125397.6909propithecus_coquereliENSPCOP0000003055897.834597.4014
ENSG00000086758homo_sapiensENSP0000026285445.450429.1495caenorhabditis_elegansY67D8C.5h.147.50330.466
ENSG00000086758homo_sapiensENSP0000026285454.915439.0261drosophila_melanogasterFBpp030926546.631733.1392
ENSG00000086758homo_sapiensENSP0000026285462.985845.3132ciona_intestinalisENSCINP0000002489664.129446.1359
ENSG00000086758homo_sapiensENSP0000026285419.250117.2382petromyzon_marinusENSPMAP0000000996484.964776.0848
ENSG00000086758homo_sapiensENSP000002628547.95617.22451petromyzon_marinusENSPMAP0000000399777.852370.6935
ENSG00000086758homo_sapiensENSP000002628545.715595.41838callorhinchus_miliiENSCMIP0000000482788.339283.7456
ENSG00000086758homo_sapiensENSP0000026285486.099781.0471latimeria_chalumnaeENSLACP0000001181891.831386.4423
ENSG00000086758homo_sapiensENSP0000026285483.859278.0979lepisosteus_oculatusENSLOCP0000001826585.901680
ENSG00000086758homo_sapiensENSP0000026285484.293678.578clupea_harengusENSCHAP0000005432889.904983.8088
ENSG00000086758homo_sapiensENSP0000026285486.625579.6525danio_rerioENSDARP0000011826584.689377.8721
ENSG00000086758homo_sapiensENSP0000026285487.860180.9099carassius_auratusENSCARP0000002304584.276377.6096
ENSG00000086758homo_sapiensENSP0000026285487.951581.0242carassius_auratusENSCARP0000013608084.290177.6512
ENSG00000086758homo_sapiensENSP000002628542.331962.21765astyanax_mexicanusENSAMXP0000003346998.076993.2692
ENSG00000086758homo_sapiensENSP0000026285487.631580.7956ictalurus_punctatusENSIPUP0000001378385.139978.4984
ENSG00000086758homo_sapiensENSP0000026285486.145478.8294esox_luciusENSELUP0000006076684.201177.0503
ENSG00000086758homo_sapiensENSP0000026285486.71779.6754electrophorus_electricusENSEEEP0000003074485.35178.4203
ENSG00000086758homo_sapiensENSP0000026285485.55178.8294oncorhynchus_kisutchENSOKIP0000509507185.94479.1916
ENSG00000086758homo_sapiensENSP0000026285487.402880.2469oncorhynchus_kisutchENSOKIP0000505237384.78677.8443
ENSG00000086758homo_sapiensENSP0000026285487.974480.7042oncorhynchus_mykissENSOMYP0000004128583.488876.5893
ENSG00000086758homo_sapiensENSP0000026285487.471480.3384oncorhynchus_mykissENSOMYP0000004111284.927978.0022
ENSG00000086758homo_sapiensENSP0000026285487.905880.8642salmo_salarENSSSAP0000014753683.063376.4096
ENSG00000086758homo_sapiensENSP0000026285482.533176.5661salmo_salarENSSSAP0000007339888.894482.4674
ENSG00000086758homo_sapiensENSP0000026285484.453678.4179salmo_truttaENSSTUP0000005600588.840882.4916
ENSG00000086758homo_sapiensENSP0000026285487.402880.3384salmo_truttaENSSTUP0000009113784.89978.0369
ENSG00000086758homo_sapiensENSP0000026285485.71179.401gadus_morhuaENSGMOP0000004661088.149581.66
ENSG00000086758homo_sapiensENSP0000026285482.144575.7887fundulus_heteroclitusENSFHEP0000002116688.128581.3098
ENSG00000086758homo_sapiensENSP0000026285487.631580.567poecilia_reticulataENSPREP0000003233183.6976.9432
ENSG00000086758homo_sapiensENSP0000026285482.624676.3832xiphophorus_maculatusENSXMAP0000001091788.03981.3885
ENSG00000086758homo_sapiensENSP0000026285484.796578.6237oryzias_latipesENSORLP0000000912889.958883.4101
ENSG00000086758homo_sapiensENSP0000026285486.488379.401cyclopterus_lumpusENSCLMP0000500888184.820677.87
ENSG00000086758homo_sapiensENSP0000026285488.157381.1843oreochromis_niloticusENSONIP0000001513084.284277.6175
ENSG00000086758homo_sapiensENSP0000026285477.480671.9936haplochromis_burtoniENSHBUP0000000168689.893983.5279
ENSG00000086758homo_sapiensENSP000002628543.657983.5208haplochromis_burtoniENSHBUP0000002254394.117690.5882
ENSG00000086758homo_sapiensENSP0000026285484.933778.9209astatotilapia_callipteraENSACLP0000000672690.345383.9494
ENSG00000086758homo_sapiensENSP0000026285486.945680.1326lates_calcariferENSLCAP0001004393585.943579.209
ENSG00000086758homo_sapiensENSP0000026285491.563887.1285xenopus_tropicalisENSXETP0000010553091.815787.3682
ENSG00000086758homo_sapiensENSP0000026285486.511282.716chrysemys_picta_belliiENSCPBP0000002432690.353486.3897
ENSG00000086758homo_sapiensENSP0000026285412.688612.3228sphenodon_punctatusENSSPUP0000002518298.754495.9075
ENSG00000086758homo_sapiensENSP000002628546.721546.51578sphenodon_punctatusENSSPUP0000002518691.304388.5093
ENSG00000086758homo_sapiensENSP0000026285413.603113.0087sphenodon_punctatusENSSPUP0000002518596.905592.671
ENSG00000086758homo_sapiensENSP000002628542.949252.69776sphenodon_punctatusENSSPUP0000002518387.162279.7297
ENSG00000086758homo_sapiensENSP000002628545.006864.73251sphenodon_punctatusENSSPUP0000002518794.396689.2241
ENSG00000086758homo_sapiensENSP0000026285474.942871.8564laticauda_laticaudataENSLLTP0000002442393.28489.4422
ENSG00000086758homo_sapiensENSP0000026285419.112918.5414laticauda_laticaudataENSLLTP0000000490290.770988.0565
ENSG00000086758homo_sapiensENSP0000026285493.369989.8034notechis_scutatusENSNSUP0000002758393.605390.0298
ENSG00000086758homo_sapiensENSP0000026285493.415689.9634pseudonaja_textilisENSPTXP0000000941993.479890.0252
ENSG00000086758homo_sapiensENSP000002628545.075454.8011anas_platyrhynchos_platyrhynchosENSAPLP0000002491078.723474.4681
ENSG00000086758homo_sapiensENSP0000026285414.700514.289gallus_gallusENSGALP0001000046596.837394.1265
ENSG00000086758homo_sapiensENSP0000026285493.347189.8262anolis_carolinensisENSACAP0000000446493.475389.9496
ENSG00000086758homo_sapiensENSP0000026285484.064978.1664neolamprologus_brichardiENSNBRP0000002022590.678284.3157
ENSG00000086758homo_sapiensENSP0000026285410.26529.73937neolamprologus_brichardiENSNBRP0000000016194.1389.3082
ENSG00000086758homo_sapiensENSP0000026285491.243787.6543naja_najaENSNNAP0000002883693.073789.4123
ENSG00000086758homo_sapiensENSP0000026285494.078690.5807podarcis_muralisENSPMRP0000003674093.842690.3535
ENSG00000086758homo_sapiensENSP0000026285410.90539.99086geospiza_fortisENSGFOP0000001729879.899573.1993
ENSG00000086758homo_sapiensENSP0000026285410.42529.55647taeniopygia_guttataENSTGUP0000002420875.496769.2053
ENSG00000086758homo_sapiensENSP0000026285486.05481.9616erpetoichthys_calabaricusENSECRP0000001368891.425887.078
ENSG00000086758homo_sapiensENSP0000026285485.093778.9438kryptolebias_marmoratusENSKMAP0000000735388.788282.3712
ENSG00000086758homo_sapiensENSP0000026285493.918690.3064salvator_merianaeENSSMRP0000002443693.832890.2238
ENSG00000086758homo_sapiensENSP0000026285483.676377.5263amphilophus_citrinellusENSACIP0000003007188.405881.9082
ENSG00000086758homo_sapiensENSP0000026285488.294581.3214dicentrarchus_labraxENSDLAP0000505111484.396977.7316
ENSG00000086758homo_sapiensENSP0000026285486.808479.8583amphiprion_perculaENSAPEP0000000208384.792378.0036
ENSG00000086758homo_sapiensENSP0000026285419.753119.2501gopherus_evgoodeiENSGEVP0000502878190.187987.8914
ENSG00000086758homo_sapiensENSP0000026285411.636911.3855chelonoidis_abingdoniiENSCABP0000001993482.362580.5825
ENSG00000086758homo_sapiensENSP0000026285483.767777.7778seriola_dumeriliENSSDUP0000001629688.609482.2733
ENSG00000086758homo_sapiensENSP0000026285486.87779.9726cottoperca_gobioENSCGOP0000002853885.068378.3076
ENSG00000086758homo_sapiensENSP0000026285487.402880.2241gasterosteus_aculeatusENSGACP0000001162988.087680.8525
ENSG00000086758homo_sapiensENSP0000026285485.002378.3493cynoglossus_semilaevisENSCSEP0000000222584.711878.0816
ENSG00000086758homo_sapiensENSP0000026285487.745880.6356poecilia_formosaENSPFOP0000001031084.724177.8587
ENSG00000086758homo_sapiensENSP0000026285487.334380.5441myripristis_murdjanENSMMDP0000503404485.669479.0087
ENSG00000086758homo_sapiensENSP0000026285489.506284.2021strigops_habroptilaENSSHBP0000502189490.68885.3139
ENSG00000086758homo_sapiensENSP0000026285450.434446.6164amphiprion_ocellarisENSAOCP0000002340287.783581.1381
ENSG00000086758homo_sapiensENSP000002628546.447196.1957amphiprion_ocellarisENSAOCP0000000607292.763289.1447
ENSG00000086758homo_sapiensENSP000002628547.407417.1102terrapene_carolina_triunguisENSTMTP0000002797688.283484.7411
ENSG00000086758homo_sapiensENSP000002628542.697762.492hucho_huchoENSHHUP0000000311386.764780.1471
ENSG00000086758homo_sapiensENSP0000026285488.248781.2529betta_splendensENSBSLP0000003979584.74278.0241
ENSG00000086758homo_sapiensENSP000002628547.887527.70462pygocentrus_nattereriENSPNAP0000003412396.100393.8719
ENSG00000086758homo_sapiensENSP0000026285451.280347.5766pygocentrus_nattereriENSPNAP0000001713886.971780.6902
ENSG00000086758homo_sapiensENSP0000026285487.357180.4755anabas_testudineusENSATEP0000003138685.903879.1367
ENSG00000086758homo_sapiensENSP000002628548.962057.63603ciona_savignyiENSCSAVP0000001093289.090975.9091
ENSG00000086758homo_sapiensENSP0000026285425.948819.0215ciona_savignyiENSCSAVP0000001079568.373550.1205
ENSG00000086758homo_sapiensENSP0000026285433.699119.9588saccharomyces_cerevisiaeYDR457W45.10426.7136
ENSG00000086758homo_sapiensENSP0000026285484.110778.075seriola_lalandi_dorsalisENSSLDP0000001160089.448183.0294
ENSG00000086758homo_sapiensENSP0000026285487.014280.2012labrus_bergyltaENSLBEP0000001357085.412978.7253
ENSG00000086758homo_sapiensENSP0000026285487.402880.6127pundamilia_nyerereiENSPNYP0000002810885.031178.4253
ENSG00000086758homo_sapiensENSP0000026285486.648479.8125mastacembelus_armatusENSMAMP0000004414185.882679.1072
ENSG00000086758homo_sapiensENSP0000026285485.436779.6525stegastes_partitusENSSPAP0000002772591.48185.2876
ENSG00000086758homo_sapiensENSP0000026285472.610967.2154oncorhynchus_tshawytschaENSOTSP0000502089988.46881.8941
ENSG00000086758homo_sapiensENSP0000026285483.744978.1207acanthochromis_polyacanthusENSAPOP0000002406989.080783.0983
ENSG00000086758homo_sapiensENSP0000026285486.008281.3214aquila_chrysaetos_chrysaetosENSACCP0002002423287.366582.6057
ENSG00000086758homo_sapiensENSP0000026285487.997381.0242nothobranchius_furzeriENSNFUP0001501261684.149577.4814
ENSG00000086758homo_sapiensENSP0000026285450.388746.6621cyprinodon_variegatusENSCVAP0000003245588.265981.7381
ENSG00000086758homo_sapiensENSP000002628549.076368.61911cyprinodon_variegatusENSCVAP0000001913395.432790.625
ENSG00000086758homo_sapiensENSP0000026285486.739880.1326denticeps_clupeoidesENSDCDP0000000776885.143678.658
ENSG00000086758homo_sapiensENSP0000026285488.248781.2071larimichthys_croceaENSLCRP0000501705284.187677.47
ENSG00000086758homo_sapiensENSP0000026285487.745880.7499takifugu_rubripesENSTRUP0000007598883.199776.5662
ENSG00000086758homo_sapiensENSP000002628548.001836.5615ficedula_albicollisENSFALP0000000662346.542638.1649
ENSG00000086758homo_sapiensENSP000002628547.544587.27023hippocampus_comesENSHCOP0000002340495.930292.4419
ENSG00000086758homo_sapiensENSP0000026285416.003715.2263hippocampus_comesENSHCOP0000000941994.339689.7574
ENSG00000086758homo_sapiensENSP0000026285488.180281.2529cyprinus_carpio_carpioENSCCRP0000015120784.564877.9215
ENSG00000086758homo_sapiensENSP0000026285488.088781.1843cyprinus_carpio_carpioENSCCRP0000016082984.310777.7024
ENSG00000086758homo_sapiensENSP0000026285484.499377.8464poecilia_latipinnaENSPLAP0000002464688.675681.6939
ENSG00000086758homo_sapiensENSP0000026285484.522277.5492sinocyclocheilus_grahamiENSSGRP0000002017684.832577.8339
ENSG00000086758homo_sapiensENSP0000026285487.3880.4298sinocyclocheilus_grahamiENSSGRP0000009728584.669977.9353
ENSG00000086758homo_sapiensENSP0000026285484.933778.9209maylandia_zebraENSMZEP0000503649090.65484.2362
ENSG00000086758homo_sapiensENSP0000026285465.409259.3736tetraodon_nigroviridisENSTNIP0000001813984.99777.1539
ENSG00000086758homo_sapiensENSP0000026285415.729314.9291tetraodon_nigroviridisENSTNIP0000000086289.350684.8052
ENSG00000086758homo_sapiensENSP0000026285484.522278.1664paramormyrops_kingsleyaeENSPKIP0000003789788.784882.1086
ENSG00000086758homo_sapiensENSP0000026285485.619678.8752scleropages_formosusENSSFOP0001501915784.04477.4237
ENSG00000086758homo_sapiensENSP0000026285487.402880.4984scleropages_formosusENSSFOP0001500242285.125878.4012
ENSG00000086758homo_sapiensENSP0000026285489.483384.7965leptobrachium_leishanenseENSLLEP0000004854891.748786.9433
ENSG00000086758homo_sapiensENSP0000026285488.111681.2757scophthalmus_maximusENSSMAP0000006853084.130177.6031
ENSG00000086758homo_sapiensENSP000002628542.30912.14906oryzias_melastigmaENSOMEP0000001684196.190589.5238

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0000139is_active_in Golgi membrane1IBAHomo_sapiens(9606)Component
GO:0000209involved_in protein polyubiquitination2IBA,IDAHomo_sapiens(9606)Process
GO:0003677enables DNA binding1ISSHomo_sapiens(9606)Function
GO:0003723enables RNA binding1HDAHomo_sapiens(9606)Function
GO:0004842enables ubiquitin-protein transferase activity1IDAHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005576located_in extracellular region1TASHomo_sapiens(9606)Component
GO:0005634is_active_in nucleus2IBA,ISSHomo_sapiens(9606)Component
GO:0005654located_in nucleoplasm1IDAHomo_sapiens(9606)Component
GO:0005737is_active_in cytoplasm2IBA,IDAHomo_sapiens(9606)Component
GO:0005739located_in mitochondrion1IEAHomo_sapiens(9606)Component
GO:0005829located_in cytosol2IDA,TASHomo_sapiens(9606)Component
GO:0006284involved_in base-excision repair2IBA,IMPHomo_sapiens(9606)Process
GO:0006338involved_in chromatin remodeling1IEAHomo_sapiens(9606)Process
GO:0006513involved_in protein monoubiquitination1IDAHomo_sapiens(9606)Process
GO:0007030involved_in Golgi organization1IBAHomo_sapiens(9606)Process
GO:0010637involved_in negative regulation of mitochondrial fusion1IMPHomo_sapiens(9606)Process
GO:0016020located_in membrane1HDAHomo_sapiens(9606)Component
GO:0030154involved_in cell differentiation1IEAHomo_sapiens(9606)Process
GO:0031398involved_in positive regulation of protein ubiquitination1IDAHomo_sapiens(9606)Process
GO:0032922involved_in circadian regulation of gene expression1IMPHomo_sapiens(9606)Process
GO:0034774located_in secretory granule lumen1TASHomo_sapiens(9606)Component
GO:0061025involved_in membrane fusion1IBAHomo_sapiens(9606)Process
GO:0061630enables ubiquitin protein ligase activity3IBA,IDA,IMPHomo_sapiens(9606)Function
GO:0070062located_in extracellular exosome1HDAHomo_sapiens(9606)Component
GO:0098779involved_in positive regulation of mitophagy in response to mitochondrial depolarization1IDAHomo_sapiens(9606)Process
GO:0140852enables histone ubiquitin ligase activity1IDAHomo_sapiens(9606)Function
GO:1903955involved_in positive regulation of protein targeting to mitochondrion1HMPHomo_sapiens(9606)Process
GO:1904813located_in ficolin-1-rich granule lumen1TASHomo_sapiens(9606)Component

Expression