Functions and Diseases

RBP Type Canonical_RBPs
Diseases Cancer Disease
Drug N.A.
Main interacting RNAs N.A.
Moonlighting functions Metabolic enzyme
Localizations N.A.
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000084774 Gene ID 790 Accession 1424
Symbol CAD Alias CDG1Z;DEE50;GATD4;EIEE50 Full Name carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
Status Confidence Length 26575 bases Strand Plus strand
Position 2 : 27217369 - 27243943 RNA binding domain RimK
Summary The de novo synthesis of pyrimidine nucleotides is required for mammalian cells to proliferate. This gene encodes a trifunctional protein which is associated with the enzymatic activities of the first 3 enzymes in the 6-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II), aspartate transcarbamoylase, and dihydroorotase. This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade, which indicates a direct link between activation of the MAPK cascade and de novo biosynthesis of pyrimidine nucleotides. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000384510 RimK PF08443 1.6e-05 1

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal

Transcripts

Name Transcript ID bp Protein Translation ID
CAD-201 ENST00000264705 7286 2225aa ENSP00000264705
CAD-202 ENST00000403525 6900 2162aa ENSP00000384510
CAD-211 ENST00000491891 662 No protein -
CAD-206 ENST00000464159 589 No protein -
CAD-207 ENST00000475695 687 No protein -
CAD-208 ENST00000479002 614 No protein -
CAD-205 ENST00000458503 806 269aa ENSP00000414742
CAD-204 ENST00000456311 837 279aa ENSP00000388740
CAD-209 ENST00000487239 748 No protein -
CAD-210 ENST00000491461 366 No protein -
CAD-203 ENST00000428460 953 293aa ENSP00000405416

Gene Model

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
52996Receptors, Interleukin-65.4860000E-006-
53012Receptors, Interleukin-65.4690000E-006-

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000084774homo_sapiensENSP0000003900745.762726.2712homo_sapiensENSP000002647057.28094.17978
ENSG00000084774homo_sapiensENSP0000023307268.333350.2homo_sapiensENSP0000026470546.067433.8427

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000084774homo_sapiensENSP0000026470598.741698.6067nomascus_leucogenysENSNLEP0000000388299.863699.7273
ENSG00000084774homo_sapiensENSP0000026470599.775399.6404pan_paniscusENSPPAP0000003785999.596299.4616
ENSG00000084774homo_sapiensENSP0000026470599.730399.4607pongo_abeliiENSPPYP0000001402599.730399.4607
ENSG00000084774homo_sapiensENSP0000026470599.820299.6854pan_troglodytesENSPTRP0000008633599.641199.5065
ENSG00000084774homo_sapiensENSP0000026470599.775399.5056gorilla_gorillaENSGGOP0000004619899.596299.327
ENSG00000084774homo_sapiensENSP0000026470595.19191.7303ornithorhynchus_anatinusENSOANP0000005158195.233891.7716
ENSG00000084774homo_sapiensENSP0000026470596.269793.3483sarcophilus_harrisiiENSSHAP0000003311595.539792.6405
ENSG00000084774homo_sapiensENSP0000026470571.101168.9888notamacropus_eugeniiENSMEUP0000001265271.325569.2065
ENSG00000084774homo_sapiensENSP0000026470596.719194.7865dasypus_novemcinctusENSDNOP0000002618095.559593.6501
ENSG00000084774homo_sapiensENSP0000026470595.146193.1685echinops_telfairiENSETEP0000000802995.103393.1267
ENSG00000084774homo_sapiensENSP0000026470598.067497.573callithrix_jacchusENSCJAP0000000200796.208195.7231
ENSG00000084774homo_sapiensENSP0000026470599.550699.191cercocebus_atysENSCATP0000001153799.550699.191
ENSG00000084774homo_sapiensENSP0000026470595.011294.382macaca_fascicularisENSMFAP0000000243298.279997.629
ENSG00000084774homo_sapiensENSP0000026470599.460799.1461macaca_mulattaENSMMUP0000004967895.96795.6635
ENSG00000084774homo_sapiensENSP0000026470599.550699.236macaca_nemestrinaENSMNEP0000001423798.795798.4835
ENSG00000084774homo_sapiensENSP0000026470599.550699.236papio_anubisENSPANP0000003097297.965597.6559
ENSG00000084774homo_sapiensENSP0000026470599.595599.236mandrillus_leucophaeusENSMLEP0000001560699.595599.236
ENSG00000084774homo_sapiensENSP0000026470585.078784tursiops_truncatusENSTTRP0000001187085.116984.0378
ENSG00000084774homo_sapiensENSP0000026470598.471997.3034vulpes_vulpesENSVVUP0000002219497.725296.5656
ENSG00000084774homo_sapiensENSP0000026470597.393395.2809mus_spretusMGP_SPRETEiJ_P006988897.393395.2809
ENSG00000084774homo_sapiensENSP0000026470598.157396.5393equus_asinusENSEASP0000501771697.41395.8073
ENSG00000084774homo_sapiensENSP0000026470598.337197.3034capra_hircusENSCHIP0000002574097.591496.5656
ENSG00000084774homo_sapiensENSP0000026470597.842796.1798loxodonta_africanaENSLAFP0000001025397.842796.1798
ENSG00000084774homo_sapiensENSP0000026470598.561897.4831panthera_leoENSPLOP0000000492998.561897.4831
ENSG00000084774homo_sapiensENSP0000026470597.887696.8539ailuropoda_melanoleucaENSAMEP0000002733193.919892.928
ENSG00000084774homo_sapiensENSP0000026470598.247297.0787bos_indicus_hybridENSBIXP0000504508597.502296.3426
ENSG00000084774homo_sapiensENSP0000026470596.943895.2809oryctolagus_cuniculusENSOCUP0000004092797.64695.971
ENSG00000084774homo_sapiensENSP0000026470598.202296.4494equus_caballusENSECAP0000003914497.457695.7181
ENSG00000084774homo_sapiensENSP0000026470597.348396.1798canis_lupus_familiarisENSCAFP0084500900898.544197.3612
ENSG00000084774homo_sapiensENSP0000026470598.561897.4831panthera_pardusENSPPRP0000000490898.561897.4831
ENSG00000084774homo_sapiensENSP0000026470598.337196.7191marmota_marmota_marmotaENSMMMP0000002381798.337196.7191
ENSG00000084774homo_sapiensENSP0000026470598.247297.3034balaenoptera_musculusENSBMSP0001001466198.247297.3034
ENSG00000084774homo_sapiensENSP0000026470597.213595.1461cavia_porcellusENSCPOP0000002501296.218994.1726
ENSG00000084774homo_sapiensENSP0000026470595.730394.6067felis_catusENSFCAP0000001404994.666793.5556
ENSG00000084774homo_sapiensENSP0000026470597.887696.6742ursus_americanusENSUAMP0000000825498.196696.9793
ENSG00000084774homo_sapiensENSP0000026470595.910193.0787monodelphis_domesticaENSMODP0000004782495.395692.5793
ENSG00000084774homo_sapiensENSP0000026470594.741693.4831bison_bison_bisonENSBBBP0000000798297.098195.8084
ENSG00000084774homo_sapiensENSP0000026470597.842796.8539monodon_monocerosENSMMNP0001500903398.417797.4231
ENSG00000084774homo_sapiensENSP0000026470597.078795.8202sus_scrofaENSSSCP0000002505297.959296.6893
ENSG00000084774homo_sapiensENSP0000026470598.42797.618microcebus_murinusENSMICP0000003341798.42797.618
ENSG00000084774homo_sapiensENSP0000026470596.988894.6517octodon_degusENSODEP0000000894996.296393.9759
ENSG00000084774homo_sapiensENSP0000026470597.528195.8202jaculus_jaculusENSJJAP0000002184597.659895.9496
ENSG00000084774homo_sapiensENSP0000026470597.707996.6742ovis_aries_rambouilletENSOARP0002000219198.282197.2423
ENSG00000084774homo_sapiensENSP0000026470597.438296.2247ursus_maritimusENSUMAP0000003025497.745796.5284
ENSG00000084774homo_sapiensENSP0000026470594.022592.0899ochotona_princepsENSOPRP0000000975194.149492.2142
ENSG00000084774homo_sapiensENSP0000026470597.797896.6742delphinapterus_leucasENSDLEP0000003053897.360296.2416
ENSG00000084774homo_sapiensENSP0000026470598.292197.2584physeter_catodonENSPCTP0000500875498.292197.2584
ENSG00000084774homo_sapiensENSP0000026470597.438295.1461mus_caroliMGP_CAROLIEiJ_P006726097.48295.1889
ENSG00000084774homo_sapiensENSP0000026470597.348395.3708mus_musculusENSMUSP0000001377397.348395.3708
ENSG00000084774homo_sapiensENSP0000026470597.797895.6854dipodomys_ordiiENSDORP0000000952997.841795.7284
ENSG00000084774homo_sapiensENSP0000026470598.38297.0787mustela_putorius_furoENSMPUP0000000945098.38297.0787
ENSG00000084774homo_sapiensENSP0000026470599.550698.8764aotus_nancymaaeENSANAP0000000935099.550698.8764
ENSG00000084774homo_sapiensENSP0000026470599.640499.236saimiri_boliviensis_boliviensisENSSBOP0000003570899.640499.236
ENSG00000084774homo_sapiensENSP0000026470599.460798.9213chlorocebus_sabaeusENSCSAP0000000593399.460798.9213
ENSG00000084774homo_sapiensENSP0000026470559.19158.427tupaia_belangeriENSTBEP0000000623660.302259.5238
ENSG00000084774homo_sapiensENSP0000026470597.797895.5955mesocricetus_auratusENSMAUP0000000313497.797895.5955
ENSG00000084774homo_sapiensENSP0000026470598.292197.3034phocoena_sinusENSPSNP0000000641297.546896.5656
ENSG00000084774homo_sapiensENSP0000026470598.516997.4831camelus_dromedariusENSCDRP0000501101698.561197.527
ENSG00000084774homo_sapiensENSP0000026470596.089994.5618carlito_syrichtaENSTSYP0000002324796.698395.1606
ENSG00000084774homo_sapiensENSP0000026470597.438294.9663rattus_norvegicusENSRNOP0000007939693.40891.0383
ENSG00000084774homo_sapiensENSP0000026470597.213596.3146prolemur_simusENSPSMP0000000475397.476396.575
ENSG00000084774homo_sapiensENSP0000026470597.887695.9101microtus_ochrogasterENSMOCP0000000523697.887695.9101
ENSG00000084774homo_sapiensENSP0000026470553.033752sorex_araneusENSSARP0000000372963.406862.1709
ENSG00000084774homo_sapiensENSP0000026470597.752895.4607peromyscus_maniculatus_bairdiiENSPEMP0000000501397.752895.4607
ENSG00000084774homo_sapiensENSP0000026470597.707996.4944bos_mutusENSBMUP0000001120998.237797.0176
ENSG00000084774homo_sapiensENSP0000026470597.393395.3708mus_spicilegusENSMSIP0000001717497.393395.3708
ENSG00000084774homo_sapiensENSP0000026470597.797895.6404cricetulus_griseus_chok1gshdENSCGRP0000101786397.753895.5975
ENSG00000084774homo_sapiensENSP0000026470593.483192pteropus_vampyrusENSPVAP0000001428694.933893.4277
ENSG00000084774homo_sapiensENSP0000026470597.393396.1348myotis_lucifugusENSMLUP0000000130397.305896.0485
ENSG00000084774homo_sapiensENSP0000026470596.179893.2135vombatus_ursinusENSVURP0001002705496.396493.4234
ENSG00000084774homo_sapiensENSP0000026470598.067496.7191rhinolophus_ferrumequinumENSRFEP0001001946698.023496.6757
ENSG00000084774homo_sapiensENSP0000026470598.42797.0337neovison_visonENSNVIP0000002173397.680696.298
ENSG00000084774homo_sapiensENSP0000026470598.247297.0787bos_taurusENSBTAP0000002378398.247297.0787
ENSG00000084774homo_sapiensENSP0000026470597.168595.0112heterocephalus_glaber_femaleENSHGLP0000000834296.131693.9973
ENSG00000084774homo_sapiensENSP0000026470599.19198.8764rhinopithecus_bietiENSRBIP0000000507799.19198.8764
ENSG00000084774homo_sapiensENSP0000026470598.067496.8539canis_lupus_dingoENSCAFP0002003153898.376997.1596
ENSG00000084774homo_sapiensENSP0000026470598.337196.8539sciurus_vulgarisENSSVLP0000503304098.381396.8975
ENSG00000084774homo_sapiensENSP0000026470596.224793.3483phascolarctos_cinereusENSPCIP0000002919596.441493.5586
ENSG00000084774homo_sapiensENSP0000026470591.910189.7978procavia_capensisENSPCAP0000001346493.592791.4417
ENSG00000084774homo_sapiensENSP0000026470597.887696nannospalax_galiliENSNGAP0000000678397.887696
ENSG00000084774homo_sapiensENSP0000026470597.662996.4494bos_grunniensENSBGRP0000001670598.236997.0163
ENSG00000084774homo_sapiensENSP0000026470597.528195.4157chinchilla_lanigeraENSCLAP0000002321596.487394.3975
ENSG00000084774homo_sapiensENSP0000026470597.977596.8539cervus_hanglu_yarkandensisENSCHYP0000001167098.508897.3791
ENSG00000084774homo_sapiensENSP0000026470598.516997.3034catagonus_wagneriENSCWAP0000001694598.516997.3034
ENSG00000084774homo_sapiensENSP0000026470598.38296.7191ictidomys_tridecemlineatusENSSTOP0000001016498.38296.7191
ENSG00000084774homo_sapiensENSP0000026470598.157396.764otolemur_garnettiiENSOGAP0000001513398.245696.8511
ENSG00000084774homo_sapiensENSP0000026470599.685499.1461cebus_imitatorENSCCAP0000003855699.685499.1461
ENSG00000084774homo_sapiensENSP0000026470598.337196.6292urocitellus_parryiiENSUPAP0001000838697.591495.8965
ENSG00000084774homo_sapiensENSP0000026470594.921393.618moschus_moschiferusENSMMSP0000000909395.738994.4243
ENSG00000084774homo_sapiensENSP0000026470599.19198.8764rhinopithecus_roxellanaENSRROP0000002606599.19198.8764
ENSG00000084774homo_sapiensENSP0000026470597.258495.3258mus_pahariMGP_PahariEiJ_P008176497.258495.3258
ENSG00000084774homo_sapiensENSP0000026470598.471997.4831propithecus_coquereliENSPCOP0000002246298.383597.3956
ENSG00000084774homo_sapiensENSP0000026470571.775356.8539caenorhabditis_elegansD2085.1.172.65757.5523
ENSG00000084774homo_sapiensENSP0000026470576.044963.5056drosophila_melanogasterFBpp008867576.079163.5342
ENSG00000084774homo_sapiensENSP0000026470511.95519.52809ciona_intestinalisENSCINP0000001825669.451755.3525
ENSG00000084774homo_sapiensENSP0000026470515.460713.1236petromyzon_marinusENSPMAP0000000420982.49470.024
ENSG00000084774homo_sapiensENSP000002647057.505625.8427eptatretus_burgeriENSEBUP0000002042369.294653.9419
ENSG00000084774homo_sapiensENSP0000026470586.112476.5843callorhinchus_miliiENSCMIP0000004221785.307275.8682
ENSG00000084774homo_sapiensENSP0000026470584.80975.6854latimeria_chalumnaeENSLACP0000001315085.655976.4412
ENSG00000084774homo_sapiensENSP0000026470587.325876.6742lepisosteus_oculatusENSLOCP0000001954786.011575.5201
ENSG00000084774homo_sapiensENSP0000026470586.471976.8539clupea_harengusENSCHAP0000002054985.816276.2712
ENSG00000084774homo_sapiensENSP0000026470586.157376.7191danio_rerioENSDARP0000012737785.964176.5471
ENSG00000084774homo_sapiensENSP0000026470586.157376.4944carassius_auratusENSCARP0000011690084.598475.1103
ENSG00000084774homo_sapiensENSP0000026470586.471976.8539carassius_auratusENSCARP0000007509386.239476.6472
ENSG00000084774homo_sapiensENSP0000026470586.112476.0899astyanax_mexicanusENSAMXP0000002889985.004475.1109
ENSG00000084774homo_sapiensENSP0000026470586.292176.2247ictalurus_punctatusENSIPUP0000000329886.253476.1905
ENSG00000084774homo_sapiensENSP0000026470586.471976.1798esox_luciusENSELUP0000002728986.200775.9409
ENSG00000084774homo_sapiensENSP0000026470586.337176.4494electrophorus_electricusENSEEEP0000004207386.143576.278
ENSG00000084774homo_sapiensENSP0000026470586.42776.1798oncorhynchus_kisutchENSOKIP0000506414886.388176.1456
ENSG00000084774homo_sapiensENSP0000026470586.247275.7303oncorhynchus_kisutchENSOKIP0000511334586.324875.7985
ENSG00000084774homo_sapiensENSP0000026470586.471976.1798oncorhynchus_mykissENSOMYP0000004091685.057574.9337
ENSG00000084774homo_sapiensENSP0000026470586.651776.1348oncorhynchus_mykissENSOMYP0000006066786.186975.7264
ENSG00000084774homo_sapiensENSP0000026470585.797875.5955salmo_salarENSSSAP0000010539885.720775.5276
ENSG00000084774homo_sapiensENSP0000026470585.932675.5506salmo_salarENSSSAP0000010813978.457168.9782
ENSG00000084774homo_sapiensENSP0000026470586.202275.9551salmo_truttaENSSTUP0000009038785.701575.5139
ENSG00000084774homo_sapiensENSP0000026470586.561876.3146salmo_truttaENSSTUP0000003742986.484176.2461
ENSG00000084774homo_sapiensENSP0000026470586.337175.9101gadus_morhuaENSGMOP0000005962185.644275.3009
ENSG00000084774homo_sapiensENSP0000026470583.685473.3933fundulus_heteroclitusENSFHEP0000000903886.203775.6019
ENSG00000084774homo_sapiensENSP000002647059.617987.77528poecilia_reticulataENSPREP0000002716678.388363.37
ENSG00000084774homo_sapiensENSP0000026470537.348332.4045xiphophorus_maculatusENSXMAP0000000546684.882573.6466
ENSG00000084774homo_sapiensENSP0000026470537.528132.4944oryzias_latipesENSORLP0000001092884.599873.2523
ENSG00000084774homo_sapiensENSP0000026470585.842775.3258cyclopterus_lumpusENSCLMP0000503681685.804175.292
ENSG00000084774homo_sapiensENSP0000026470586.022575.5955oreochromis_niloticusENSONIP0000001986885.791175.3922
ENSG00000084774homo_sapiensENSP000002647059.752817.68539haplochromis_burtoniENSHBUP0000002207980.370463.3333
ENSG00000084774homo_sapiensENSP000002647058.764046.74157astatotilapia_callipteraENSACLP0000001014775.581458.1395
ENSG00000084774homo_sapiensENSP0000026470586.202275.8652astatotilapia_callipteraENSACLP0000000364485.85575.5595
ENSG00000084774homo_sapiensENSP0000026470586.42776.0449sparus_aurataENSSAUP0001001103785.809975.502
ENSG00000084774homo_sapiensENSP0000026470586.921376.4944lates_calcariferENSLCAP0001002356486.493776.1181
ENSG00000084774homo_sapiensENSP0000026470587.865278.5618xenopus_tropicalisENSXETP0000006965986.427977.2767
ENSG00000084774homo_sapiensENSP0000026470586.741678.3371chrysemys_picta_belliiENSCPBP0000003108586.702678.3019
ENSG00000084774homo_sapiensENSP0000026470567.460760.0449sphenodon_punctatusENSSPUP0000001400680.267471.4438
ENSG00000084774homo_sapiensENSP0000026470588.674281.0337crocodylus_porosusENSCPRP0000500561388.277480.6711
ENSG00000084774homo_sapiensENSP0000026470581.842775.191laticauda_laticaudataENSLLTP0000002038986.962879.8949
ENSG00000084774homo_sapiensENSP0000026470587.595580.4494notechis_scutatusENSNSUP0000000700587.438380.3051
ENSG00000084774homo_sapiensENSP0000026470588.224780.809pseudonaja_textilisENSPTXP0000001511187.712280.3396
ENSG00000084774homo_sapiensENSP0000026470515.685413.0787anas_platyrhynchos_platyrhynchosENSAPLP0000002213868.565857.1709
ENSG00000084774homo_sapiensENSP0000026470588.404581.1685gallus_gallusENSGALP0001001236683.48976.6553
ENSG00000084774homo_sapiensENSP0000026470571.19165.1685meleagris_gallopavoENSMGAP0000001488482.715475.718
ENSG00000084774homo_sapiensENSP0000026470588.179881.1236parus_majorENSPMJP0000000028688.378481.3063
ENSG00000084774homo_sapiensENSP0000026470527.640425.3483anolis_carolinensisENSACAP0000000000283.220676.3194
ENSG00000084774homo_sapiensENSP0000026470582.921372.8989neolamprologus_brichardiENSNBRP0000001286886.457476.0075
ENSG00000084774homo_sapiensENSP0000026470566.42759.9101naja_najaENSNNAP0000000427085.040376.6973
ENSG00000084774homo_sapiensENSP0000026470586.606779.7303podarcis_muralisENSPMRP0000000698287.313180.3806
ENSG00000084774homo_sapiensENSP0000026470586.921377.2135erpetoichthys_calabaricusENSECRP0000001258985.31175.783
ENSG00000084774homo_sapiensENSP0000026470580.629271.1461kryptolebias_marmoratusENSKMAP0000001730286.2576.1058
ENSG00000084774homo_sapiensENSP0000026470587.595580.2697salvator_merianaeENSSMRP0000002068786.583779.3425
ENSG00000084774homo_sapiensENSP0000026470586.247276.2697amphilophus_citrinellusENSACIP0000000135686.324876.3383
ENSG00000084774homo_sapiensENSP0000026470586.651776.1798dicentrarchus_labraxENSDLAP0000504337586.071475.6696
ENSG00000084774homo_sapiensENSP0000026470583.011273.0787amphiprion_perculaENSAPEP0000001811186.672976.3022
ENSG00000084774homo_sapiensENSP0000026470586.112476.1798oryzias_sinensisENSOSIP0000004397485.688775.805
ENSG00000084774homo_sapiensENSP0000026470589.258480.8539gopherus_evgoodeiENSGEVP0000500856488.739980.3843
ENSG00000084774homo_sapiensENSP0000026470588.359680chelonoidis_abingdoniiENSCABP0000000696889.120680.689
ENSG00000084774homo_sapiensENSP0000026470583.460773.3034seriola_dumeriliENSSDUP0000000465886.735276.1794
ENSG00000084774homo_sapiensENSP0000026470585.168574.8764cottoperca_gobioENSCGOP0000004764985.015774.742
ENSG00000084774homo_sapiensENSP0000026470556.404550.2472cottoperca_gobioENSCGOP0000004814784.854675.5916
ENSG00000084774homo_sapiensENSP0000026470583.280976.764anser_brachyrhynchusENSABRP0000000685687.405780.566
ENSG00000084774homo_sapiensENSP0000026470584.76474.8315gasterosteus_aculeatusENSGACP0000000803884.271774.3968
ENSG00000084774homo_sapiensENSP0000026470584.449473.4831cynoglossus_semilaevisENSCSEP0000000709684.907473.8816
ENSG00000084774homo_sapiensENSP0000026470586.561876.1798poecilia_formosaENSPFOP0000000216686.213175.8729
ENSG00000084774homo_sapiensENSP0000026470586.561876.1348myripristis_murdjanENSMMDP0000503988786.639776.2033
ENSG00000084774homo_sapiensENSP0000026470585.258474.3371sander_luciopercaENSSLUP0000005498384.801173.9383
ENSG00000084774homo_sapiensENSP0000026470588.76481.7528strigops_habroptilaENSSHBP0000502106888.169681.2054
ENSG00000084774homo_sapiensENSP0000026470582.966373.0787amphiprion_ocellarisENSAOCP0000002153386.748176.4098
ENSG00000084774homo_sapiensENSP0000026470515.820213.573terrapene_carolina_triunguisENSTMTP0000002793070.541160.521
ENSG00000084774homo_sapiensENSP0000026470586.696676.2697hucho_huchoENSHHUP0000001379486.579976.167
ENSG00000084774homo_sapiensENSP0000026470585.61875.5955hucho_huchoENSHHUP0000005928685.656575.6295
ENSG00000084774homo_sapiensENSP0000026470586.292176.8989pygocentrus_nattereriENSPNAP0000000075386.917277.4559
ENSG00000084774homo_sapiensENSP0000026470586.516975.8652anabas_testudineusENSATEP0000003285586.322975.6951
ENSG00000084774homo_sapiensENSP0000026470526.022520.9888ciona_savignyiENSCSAVP0000000797372.37558.375
ENSG00000084774homo_sapiensENSP0000026470511.68548.22472saccharomyces_cerevisiaeYOR303W63.260344.5255
ENSG00000084774homo_sapiensENSP0000026470566.651750.0225saccharomyces_cerevisiaeYJL130C66.982850.271
ENSG00000084774homo_sapiensENSP000002647057.011245.4382seriola_lalandi_dorsalisENSSLDP0000000999159.090945.8333
ENSG00000084774homo_sapiensENSP0000026470586.247275.6854seriola_lalandi_dorsalisENSSLDP0000001009686.092475.5496
ENSG00000084774homo_sapiensENSP0000026470580.76470.6966labrus_bergyltaENSLBEP0000002188984.445573.9192
ENSG00000084774homo_sapiensENSP0000026470531.640428.2697labrus_bergyltaENSLBEP0000000490881.199572.549
ENSG00000084774homo_sapiensENSP000002647059.617987.68539labrus_bergyltaENSLBEP0000000834479.259363.3333
ENSG00000084774homo_sapiensENSP000002647055.078653.59551pundamilia_nyerereiENSPNYP0000000810966.470647.0588
ENSG00000084774homo_sapiensENSP0000026470586.112475.5955mastacembelus_armatusENSMAMP0000002851285.803875.3247
ENSG00000084774homo_sapiensENSP0000026470586.516976.2697stegastes_partitusENSSPAP0000000457386.168375.9624
ENSG00000084774homo_sapiensENSP0000026470586.202275.6854oncorhynchus_tshawytschaENSOTSP0000509707286.163575.6514
ENSG00000084774homo_sapiensENSP0000026470586.202275.6854oncorhynchus_tshawytschaENSOTSP0000501849086.163575.6514
ENSG00000084774homo_sapiensENSP0000026470586.561876.2697oncorhynchus_tshawytschaENSOTSP0000505810686.445276.167
ENSG00000084774homo_sapiensENSP0000026470586.38276.1798acanthochromis_polyacanthusENSAPOP0000001494486.03475.8729
ENSG00000084774homo_sapiensENSP000002647058.629216.83146cyprinodon_variegatusENSCVAP0000001467573.282458.0153
ENSG00000084774homo_sapiensENSP0000026470586.202276.2697denticeps_clupeoidesENSDCDP0000005427386.00976.0987
ENSG00000084774homo_sapiensENSP0000026470583.550673.2584larimichthys_croceaENSLCRP0000505636785.43274.9081
ENSG00000084774homo_sapiensENSP0000026470585.977575.8652takifugu_rubripesENSTRUP0000007091085.669575.5934
ENSG00000084774homo_sapiensENSP000002647059.528097.41573hippocampus_comesENSHCOP0000001050276.25959.3525
ENSG00000084774homo_sapiensENSP000002647056.56184.80899hippocampus_comesENSHCOP0000001558278.918957.8378
ENSG00000084774homo_sapiensENSP0000026470554.651748.1348hippocampus_comesENSHCOP0000001052285.815175.5822
ENSG00000084774homo_sapiensENSP0000026470586.38276.809cyprinus_carpio_carpioENSCCRP0000012252086.149776.6024
ENSG00000084774homo_sapiensENSP0000026470586.337176.8539cyprinus_carpio_carpioENSCCRP0000012189185.644276.2372
ENSG00000084774homo_sapiensENSP0000026470537.438232.6292poecilia_latipinnaENSPLAP0000000651485.523674.538
ENSG00000084774homo_sapiensENSP000002647054.988763.86517sinocyclocheilus_grahamiENSSGRP0000000634278.16960.5634
ENSG00000084774homo_sapiensENSP0000026470566.337160.2697sinocyclocheilus_grahamiENSSGRP0000009836587.285679.3022
ENSG00000084774homo_sapiensENSP000002647057.101125.25843maylandia_zebraENSMZEP0000501755168.103450.431
ENSG00000084774homo_sapiensENSP0000026470582.337172.3596maylandia_zebraENSMZEP0000502622785.527575.1634
ENSG00000084774homo_sapiensENSP000002647058.808996.74157maylandia_zebraENSMZEP0000503791175.095857.4713
ENSG00000084774homo_sapiensENSP0000026470586.157375.9101tetraodon_nigroviridisENSTNIP0000000811885.964175.7399
ENSG00000084774homo_sapiensENSP0000026470583.325873.8876paramormyrops_kingsleyaeENSPKIP0000003745886.757176.9303
ENSG00000084774homo_sapiensENSP0000026470586.471977.0787scleropages_formosusENSSFOP0001505435386.901577.4616
ENSG00000084774homo_sapiensENSP0000026470547.505641.2584leptobrachium_leishanenseENSLLEP0000004384157.854450.2463
ENSG00000084774homo_sapiensENSP0000026470554.651747.9551scophthalmus_maximusENSSMAP0000000877179.737769.9672
ENSG00000084774homo_sapiensENSP000002647058.584276.78652oryzias_melastigmaENSOMEP0000001611474.90259.2157
ENSG00000084774homo_sapiensENSP0000026470513.033710.427oryzias_melastigmaENSOMEP0000003237777.540162.0321

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0001889involved_in liver development1IEAHomo_sapiens(9606)Process
GO:0004070enables aspartate carbamoyltransferase activity2IBA,ISSHomo_sapiens(9606)Function
GO:0004088contributes_to carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity2IBA,ISSHomo_sapiens(9606)Function
GO:0004151enables dihydroorotase activity3IBA,IDA,ISSHomo_sapiens(9606)Function
GO:0004672enables protein kinase activity1ISSHomo_sapiens(9606)Function
GO:0005524enables ATP binding1ISSHomo_sapiens(9606)Function
GO:0005634located_in nucleus1IDAHomo_sapiens(9606)Component
GO:0005737is_active_in cytoplasm1IBAHomo_sapiens(9606)Component
GO:0005829is_active_in cytosol3IBA,IDA,TASHomo_sapiens(9606)Component
GO:0006207involved_in de novo pyrimidine nucleobase biosynthetic process3IBA,IDA,ISSHomo_sapiens(9606)Process
GO:0006225involved_in UDP biosynthetic process1IDAHomo_sapiens(9606)Process
GO:0006228involved_in UTP biosynthetic process1IBAHomo_sapiens(9606)Process
GO:0006541involved_in glutamine metabolic process2IBA,ISSHomo_sapiens(9606)Process
GO:0006805involved_in xenobiotic metabolic process1IEAHomo_sapiens(9606)Process
GO:0007507involved_in heart development1IEAHomo_sapiens(9606)Process
GO:0007565involved_in female pregnancy1IEAHomo_sapiens(9606)Process
GO:0007595involved_in lactation1IEAHomo_sapiens(9606)Process
GO:0008270enables zinc ion binding1IDAHomo_sapiens(9606)Function
GO:0014075involved_in response to amine1IEAHomo_sapiens(9606)Process
GO:0016020located_in membrane1HDAHomo_sapiens(9606)Component
GO:0016363located_in nuclear matrix1IDAHomo_sapiens(9606)Component
GO:0018107involved_in peptidyl-threonine phosphorylation1ISSHomo_sapiens(9606)Process
GO:0019240involved_in citrulline biosynthetic process1IBAHomo_sapiens(9606)Process
GO:0019899enables enzyme binding1IPIHomo_sapiens(9606)Function
GO:0031000involved_in response to caffeine1IEAHomo_sapiens(9606)Process
GO:0031100involved_in animal organ regeneration1IEAHomo_sapiens(9606)Process
GO:0032868involved_in response to insulin1IEAHomo_sapiens(9606)Process
GO:0032991part_of protein-containing complex1IEAHomo_sapiens(9606)Component
GO:0033574involved_in response to testosterone1IEAHomo_sapiens(9606)Process
GO:0042594involved_in response to starvation1IEAHomo_sapiens(9606)Process
GO:0042802enables identical protein binding2IPI,ISSHomo_sapiens(9606)Function
GO:0042995located_in cell projection1ISSHomo_sapiens(9606)Component
GO:0043025located_in neuronal cell body1ISSHomo_sapiens(9606)Component
GO:0043195located_in terminal bouton1ISSHomo_sapiens(9606)Component
GO:0044205involved_in de novo UMP biosynthetic process2IDA,IEAHomo_sapiens(9606)Process
GO:0046777involved_in protein autophosphorylation1ISSHomo_sapiens(9606)Process
GO:0051414involved_in response to cortisol1IEAHomo_sapiens(9606)Process
GO:0070062located_in extracellular exosome1HDAHomo_sapiens(9606)Component
GO:0070335enables aspartate binding1ISSHomo_sapiens(9606)Function
GO:0071364involved_in cellular response to epidermal growth factor stimulus1IEAHomo_sapiens(9606)Process

Expression