RBP Type
Canonical_RBPs
Diseases
CancerFlaviviruses SARS-COV-2 Dengue
Drug
N.A.
Main interacting RNAs
diverse
Moonlighting functions
N.A.
Localizations
N.A.
BulkPerturb-seq
N.A.
Ensembl ID ENSG00000083520 Gene ID
22894
Accession
20604
Symbol
DIS3
Alias
RRP44;dis3p;EXOSC11;KIAA1008;2810028N01Rik
Full Name
DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease
Status
Confidence
Length
29928 bases
Strand
Minus strand
Position
13 : 72752169 - 72782096
RNA binding domain
PIN_4 , OB_Dis3 , RNB , CSD2
Summary
Enables 3'-5'-exoribonuclease activity; endonuclease activity; and guanyl-nucleotide exchange factor activity. Involved in CUT catabolic process and rRNA catabolic process. Located in cytosol and nucleoplasm. Part of nuclear exosome (RNase complex). [provided by Alliance of Genome Resources, Apr 2022]
RNA binding domains (RBDs)
Protein
Domain
Pfam ID
E-value
Domain number
ENSP00000436350
OB_Dis3
PF17849
1.4e-21
1
ENSP00000436350
CSD2
PF17876
2.6e-08
2
ENSP00000436350
RNB
PF00773
1.4e-31
3
ENSP00000436350
PIN_4
PF13638
2.8e-14
4
ENSP00000440058
OB_Dis3
PF17849
1.9e-21
1
ENSP00000440058
CSD2
PF17876
6.6e-08
2
ENSP00000440058
RNB
PF00773
5.8e-98
3
ENSP00000367011
OB_Dis3
PF17849
2.3e-21
1
ENSP00000367011
CSD2
PF17876
8.8e-08
2
ENSP00000367011
RNB
PF00773
7.6e-98
3
ENSP00000367011
PIN_4
PF13638
6.5e-06
4
ENSP00000366997
OB_Dis3
PF17849
2.4e-21
1
ENSP00000366997
CSD2
PF17876
9.3e-08
2
ENSP00000366997
RNB
PF00773
7.4e-98
3
ENSP00000366997
PIN_4
PF13638
2.2e-14
4
RNA binding proteomes (RBPomes)
Pubmed ID
Full Name
Cell
Author
Time
Doi
Literatures on RNA binding capacity
Pubmed ID
Title
Author
Time
Journal
Name
Transcript ID
bp
Protein
Translation ID
DIS3-201
ENST00000377767
10571
958aa
ENSP00000366997
DIS3-202
ENST00000377780
5232
928aa
ENSP00000367011
DIS3-204
ENST00000490646
2934
559aa
ENSP00000436350
DIS3-203
ENST00000475871
716
No protein
-
DIS3-205
ENST00000545453
3651
796aa
ENSP00000440058
Pathway ID
Pathway Name
Source
ensgID
Trait
pValue
Pubmed ID
60389 Blood Pressure 2.2591816E-006 - 102323 Emotions 5E-6 27089181
ensgID SNP Chromosome Position
Trait PubmedID Or or BEAT
EFO ID
Protein-Protein Interaction (PPI)
Ensembl ID
Source
Target
Species
Protein ID
Perc_pos
Perc_id
Species
Protein ID
Perc_pos
Perc_id
ENSG00000083520 homo_sapiens ENSP00000321711 51.6129 32.5427 homo_sapiens ENSP00000366997 56.785 35.8038 ENSG00000083520 homo_sapiens ENSP00000315569 44.4068 28.7006 homo_sapiens ENSP00000366997 41.023 26.5136
Ensembl ID
Source
Target
Species
Protein ID
Perc_pos
Perc_id
Species
Protein ID
Perc_pos
Perc_id
ENSG00000083520 homo_sapiens ENSP00000366997 99.6868 98.7474 nomascus_leucogenys ENSNLEP00000019502 99.6868 98.7474 ENSG00000083520 homo_sapiens ENSP00000366997 99.7912 99.4781 pan_paniscus ENSPPAP00000038153 99.7912 99.4781 ENSG00000083520 homo_sapiens ENSP00000366997 99.3737 98.7474 pongo_abelii ENSPPYP00000006166 99.3737 98.7474 ENSG00000083520 homo_sapiens ENSP00000366997 99.7912 99.4781 pan_troglodytes ENSPTRP00000053467 99.7912 99.4781 ENSG00000083520 homo_sapiens ENSP00000366997 99.7912 99.3737 gorilla_gorilla ENSGGOP00000006491 99.7912 99.3737 ENSG00000083520 homo_sapiens ENSP00000366997 94.6764 87.6827 ornithorhynchus_anatinus ENSOANP00000015897 90.0695 83.4161 ENSG00000083520 homo_sapiens ENSP00000366997 94.8852 87.5783 sarcophilus_harrisii ENSSHAP00000042233 94.7862 87.487 ENSG00000083520 homo_sapiens ENSP00000366997 64.6138 59.1858 notamacropus_eugenii ENSMEUP00000003337 66.9913 61.3636 ENSG00000083520 homo_sapiens ENSP00000366997 77.3486 74.9478 choloepus_hoffmanni ENSCHOP00000007755 84.109 81.4983 ENSG00000083520 homo_sapiens ENSP00000366997 96.0334 91.9624 dasypus_novemcinctus ENSDNOP00000002611 96.4361 92.348 ENSG00000083520 homo_sapiens ENSP00000366997 85.6994 82.4635 erinaceus_europaeus ENSEEUP00000000218 92.2472 88.764 ENSG00000083520 homo_sapiens ENSP00000366997 82.881 78.6012 echinops_telfairi ENSETEP00000013269 96.0097 91.052 ENSG00000083520 homo_sapiens ENSP00000366997 98.7474 97.286 callithrix_jacchus ENSCJAP00000039325 98.6444 97.1846 ENSG00000083520 homo_sapiens ENSP00000366997 99.4781 98.643 cercocebus_atys ENSCATP00000028885 99.4781 98.643 ENSG00000083520 homo_sapiens ENSP00000366997 99.2693 98.4342 macaca_fascicularis ENSMFAP00000013041 99.2693 98.4342 ENSG00000083520 homo_sapiens ENSP00000366997 99.2693 98.1211 macaca_mulatta ENSMMUP00000001068 99.2693 98.1211 ENSG00000083520 homo_sapiens ENSP00000366997 99.4781 98.4342 macaca_nemestrina ENSMNEP00000011920 99.4781 98.4342 ENSG00000083520 homo_sapiens ENSP00000366997 99.2693 98.5386 papio_anubis ENSPANP00000054590 99.2693 98.5386 ENSG00000083520 homo_sapiens ENSP00000366997 99.3737 98.3299 mandrillus_leucophaeus ENSMLEP00000013033 99.3737 98.3299 ENSG00000083520 homo_sapiens ENSP00000366997 97.0772 92.5887 tursiops_truncatus ENSTTRP00000003996 97.0772 92.5887 ENSG00000083520 homo_sapiens ENSP00000366997 98.2255 94.6764 vulpes_vulpes ENSVVUP00000024678 98.2255 94.6764 ENSG00000083520 homo_sapiens ENSP00000366997 96.3466 90.9186 mus_spretus MGP_SPRETEiJ_P0039266 96.3466 90.9186 ENSG00000083520 homo_sapiens ENSP00000366997 98.5386 94.8852 equus_asinus ENSEASP00005022805 98.5386 94.8852 ENSG00000083520 homo_sapiens ENSP00000366997 97.5992 93.5282 capra_hircus ENSCHIP00000014300 90.1639 86.4031 ENSG00000083520 homo_sapiens ENSP00000366997 97.8079 93.3194 loxodonta_africana ENSLAFP00000007646 98.0126 93.5146 ENSG00000083520 homo_sapiens ENSP00000366997 98.2255 94.7808 panthera_leo ENSPLOP00000004922 98.2255 94.7808 ENSG00000083520 homo_sapiens ENSP00000366997 97.9123 94.1545 ailuropoda_melanoleuca ENSAMEP00000022420 97.9123 94.1545 ENSG00000083520 homo_sapiens ENSP00000366997 97.286 93.215 bos_indicus_hybrid ENSBIXP00005027797 97.286 93.215 ENSG00000083520 homo_sapiens ENSP00000366997 97.7036 94.572 oryctolagus_cuniculus ENSOCUP00000005760 97.8056 94.6708 ENSG00000083520 homo_sapiens ENSP00000366997 96.8685 93.3194 equus_caballus ENSECAP00000057223 95.6701 92.1649 ENSG00000083520 homo_sapiens ENSP00000366997 98.2255 94.6764 canis_lupus_familiaris ENSCAFP00845030912 98.2255 94.6764 ENSG00000083520 homo_sapiens ENSP00000366997 98.2255 94.7808 panthera_pardus ENSPPRP00000015948 98.2255 94.7808 ENSG00000083520 homo_sapiens ENSP00000366997 97.4948 94.9896 marmota_marmota_marmota ENSMMMP00000019324 97.4948 94.9896 ENSG00000083520 homo_sapiens ENSP00000366997 58.7683 55.6367 balaenoptera_musculus ENSBMSP00010023242 96.2393 91.1111 ENSG00000083520 homo_sapiens ENSP00000366997 96.9729 93.0063 cavia_porcellus ENSCPOP00000025401 94.1236 90.2736 ENSG00000083520 homo_sapiens ENSP00000366997 98.3299 94.9896 felis_catus ENSFCAP00000046298 98.3299 94.9896 ENSG00000083520 homo_sapiens ENSP00000366997 97.8079 93.6326 ursus_americanus ENSUAMP00000036977 91.8627 87.9412 ENSG00000083520 homo_sapiens ENSP00000366997 95.3027 87.0564 monodelphis_domestica ENSMODP00000000245 95.2033 86.9656 ENSG00000083520 homo_sapiens ENSP00000366997 97.4948 93.4238 bison_bison_bison ENSBBBP00000028042 97.4948 93.4238 ENSG00000083520 homo_sapiens ENSP00000366997 97.0772 92.4843 monodon_monoceros ENSMMNP00015026504 97.0772 92.4843 ENSG00000083520 homo_sapiens ENSP00000366997 98.4342 94.3633 sus_scrofa ENSSSCP00000060654 98.4342 94.3633 ENSG00000083520 homo_sapiens ENSP00000366997 98.4342 94.9896 microcebus_murinus ENSMICP00000023246 98.4342 94.9896 ENSG00000083520 homo_sapiens ENSP00000366997 97.0772 93.215 octodon_degus ENSODEP00000008525 97.0772 93.215 ENSG00000083520 homo_sapiens ENSP00000366997 97.1816 93.737 jaculus_jaculus ENSJJAP00000007137 97.1816 93.737 ENSG00000083520 homo_sapiens ENSP00000366997 97.7036 93.6326 ovis_aries_rambouillet ENSOARP00020010192 97.7036 93.6326 ENSG00000083520 homo_sapiens ENSP00000366997 93.737 88.7265 ursus_maritimus ENSUMAP00000013718 92.482 87.5386 ENSG00000083520 homo_sapiens ENSP00000366997 95.0939 90.3967 ochotona_princeps ENSOPRP00000014507 95.5929 90.8709 ENSG00000083520 homo_sapiens ENSP00000366997 96.9729 92.4843 delphinapterus_leucas ENSDLEP00000017307 96.9729 92.4843 ENSG00000083520 homo_sapiens ENSP00000366997 97.4948 93.1106 physeter_catodon ENSPCTP00005011061 97.4948 93.1106 ENSG00000083520 homo_sapiens ENSP00000366997 96.5553 91.2317 mus_caroli MGP_CAROLIEiJ_P0037524 96.5553 91.2317 ENSG00000083520 homo_sapiens ENSP00000366997 96.4509 91.1273 mus_musculus ENSMUSP00000041906 96.4509 91.1273 ENSG00000083520 homo_sapiens ENSP00000366997 94.4676 91.5449 dipodomys_ordii ENSDORP00000006840 95.7672 92.8042 ENSG00000083520 homo_sapiens ENSP00000366997 97.9123 94.0501 mustela_putorius_furo ENSMPUP00000010178 97.9123 94.0501 ENSG00000083520 homo_sapiens ENSP00000366997 99.0605 97.1816 aotus_nancymaae ENSANAP00000015482 98.9572 97.0803 ENSG00000083520 homo_sapiens ENSP00000366997 99.0605 97.286 saimiri_boliviensis_boliviensis ENSSBOP00000023746 98.9572 97.1846 ENSG00000083520 homo_sapiens ENSP00000366997 97.1816 92.5887 vicugna_pacos ENSVPAP00000003324 97.7941 93.1723 ENSG00000083520 homo_sapiens ENSP00000366997 99.3737 98.3299 chlorocebus_sabaeus ENSCSAP00000013644 99.3737 98.3299 ENSG00000083520 homo_sapiens ENSP00000366997 77.7662 75.261 tupaia_belangeri ENSTBEP00000005901 89.759 86.8675 ENSG00000083520 homo_sapiens ENSP00000366997 96.4509 92.5887 mesocricetus_auratus ENSMAUP00000015335 96.4509 92.5887 ENSG00000083520 homo_sapiens ENSP00000366997 96.9729 92.38 phocoena_sinus ENSPSNP00000017456 96.9729 92.38 ENSG00000083520 homo_sapiens ENSP00000366997 98.3299 93.9457 camelus_dromedarius ENSCDRP00005005830 98.3299 93.9457 ENSG00000083520 homo_sapiens ENSP00000366997 97.7036 94.9896 carlito_syrichta ENSTSYP00000006824 98.1132 95.3878 ENSG00000083520 homo_sapiens ENSP00000366997 91.4405 87.3695 panthera_tigris_altaica ENSPTIP00000020461 96.5821 92.2822 ENSG00000083520 homo_sapiens ENSP00000366997 96.6597 92.0668 rattus_norvegicus ENSRNOP00000029411 90.3415 86.0488 ENSG00000083520 homo_sapiens ENSP00000366997 98.4342 94.9896 prolemur_simus ENSPSMP00000010939 98.4342 94.9896 ENSG00000083520 homo_sapiens ENSP00000366997 53.7578 51.0438 sorex_araneus ENSSARP00000010658 97.5379 92.6136 ENSG00000083520 homo_sapiens ENSP00000366997 55.3236 52.1921 sorex_araneus ENSSARP00000007820 55.2659 52.1376 ENSG00000083520 homo_sapiens ENSP00000366997 96.5553 92.5887 peromyscus_maniculatus_bairdii ENSPEMP00000022331 96.5553 92.5887 ENSG00000083520 homo_sapiens ENSP00000366997 97.4948 93.3194 bos_mutus ENSBMUP00000031716 97.4948 93.3194 ENSG00000083520 homo_sapiens ENSP00000366997 96.2422 90.9186 mus_spicilegus ENSMSIP00000019649 96.2422 90.9186 ENSG00000083520 homo_sapiens ENSP00000366997 96.5553 92.4843 cricetulus_griseus_chok1gshd ENSCGRP00001024655 96.5553 92.4843 ENSG00000083520 homo_sapiens ENSP00000366997 88.9353 85.595 pteropus_vampyrus ENSPVAP00000011927 88.9353 85.595 ENSG00000083520 homo_sapiens ENSP00000366997 98.2255 93.9457 myotis_lucifugus ENSMLUP00000000509 98.0208 93.75 ENSG00000083520 homo_sapiens ENSP00000366997 95.3027 87.6827 vombatus_ursinus ENSVURP00010012329 95.2033 87.5912 ENSG00000083520 homo_sapiens ENSP00000366997 97.4948 93.4238 rhinolophus_ferrumequinum ENSRFEP00010002532 97.4948 93.4238 ENSG00000083520 homo_sapiens ENSP00000366997 98.0167 94.1545 neovison_vison ENSNVIP00000011157 98.0167 94.1545 ENSG00000083520 homo_sapiens ENSP00000366997 97.286 93.215 bos_taurus ENSBTAP00000026500 97.286 93.215 ENSG00000083520 homo_sapiens ENSP00000366997 97.286 93.6326 heterocephalus_glaber_female ENSHGLP00000019211 97.286 93.6326 ENSG00000083520 homo_sapiens ENSP00000366997 99.2693 98.0167 rhinopithecus_bieti ENSRBIP00000020512 99.2693 98.0167 ENSG00000083520 homo_sapiens ENSP00000366997 98.2255 94.6764 canis_lupus_dingo ENSCAFP00020033516 92.7094 89.3596 ENSG00000083520 homo_sapiens ENSP00000366997 97.286 94.6764 sciurus_vulgaris ENSSVLP00005003288 97.286 94.6764 ENSG00000083520 homo_sapiens ENSP00000366997 95.0939 87.3695 phascolarctos_cinereus ENSPCIP00000024469 88.5326 81.3411 ENSG00000083520 homo_sapiens ENSP00000366997 92.6931 89.0397 procavia_capensis ENSPCAP00000010422 92.887 89.2259 ENSG00000083520 homo_sapiens ENSP00000366997 97.7036 93.5282 nannospalax_galili ENSNGAP00000018453 97.7036 93.5282 ENSG00000083520 homo_sapiens ENSP00000366997 97.4948 93.3194 bos_grunniens ENSBGRP00000009858 97.4948 93.3194 ENSG00000083520 homo_sapiens ENSP00000366997 97.286 93.5282 chinchilla_lanigera ENSCLAP00000004825 97.286 93.5282 ENSG00000083520 homo_sapiens ENSP00000366997 97.5992 93.5282 cervus_hanglu_yarkandensis ENSCHYP00000020949 97.5992 93.5282 ENSG00000083520 homo_sapiens ENSP00000366997 97.9123 93.8413 catagonus_wagneri ENSCWAP00000027317 97.9123 93.8413 ENSG00000083520 homo_sapiens ENSP00000366997 97.8079 95.3027 ictidomys_tridecemlineatus ENSSTOP00000000278 97.8079 95.3027 ENSG00000083520 homo_sapiens ENSP00000366997 97.8079 94.2589 otolemur_garnettii ENSOGAP00000008819 97.8079 94.2589 ENSG00000083520 homo_sapiens ENSP00000366997 99.0605 97.3904 cebus_imitator ENSCCAP00000022952 98.9572 97.2888 ENSG00000083520 homo_sapiens ENSP00000366997 97.8079 95.3027 urocitellus_parryii ENSUPAP00010015255 97.8079 95.3027 ENSG00000083520 homo_sapiens ENSP00000366997 97.4948 93.0063 moschus_moschiferus ENSMMSP00000000012 97.4948 93.0063 ENSG00000083520 homo_sapiens ENSP00000366997 99.2693 98.0167 rhinopithecus_roxellana ENSRROP00000003065 99.2693 98.0167 ENSG00000083520 homo_sapiens ENSP00000366997 96.5553 91.4405 mus_pahari MGP_PahariEiJ_P0085607 96.5553 91.4405 ENSG00000083520 homo_sapiens ENSP00000366997 91.2317 88.5177 propithecus_coquereli ENSPCOP00000027201 98.4234 95.4955 ENSG00000083520 homo_sapiens ENSP00000366997 61.691 45.0939 caenorhabditis_elegans C04G2.6.1 61.4984 44.9532 ENSG00000083520 homo_sapiens ENSP00000366997 72.4426 55.9499 drosophila_melanogaster FBpp0083989 70.6721 54.5825 ENSG00000083520 homo_sapiens ENSP00000366997 72.547 57.9332 ciona_intestinalis ENSCINP00000030387 75.8734 60.5895 ENSG00000083520 homo_sapiens ENSP00000366997 11.691 8.5595 petromyzon_marinus ENSPMAP00000008133 70.8861 51.8987 ENSG00000083520 homo_sapiens ENSP00000366997 11.5866 8.35073 petromyzon_marinus ENSPMAP00000009187 68.5185 49.3827 ENSG00000083520 homo_sapiens ENSP00000366997 10.6472 8.35073 petromyzon_marinus ENSPMAP00000004168 82.9268 65.0406 ENSG00000083520 homo_sapiens ENSP00000366997 10.4384 8.14196 petromyzon_marinus ENSPMAP00000004763 81.3008 63.4146 ENSG00000083520 homo_sapiens ENSP00000366997 10.4384 8.14196 petromyzon_marinus ENSPMAP00000010028 81.3008 63.4146 ENSG00000083520 homo_sapiens ENSP00000366997 24.6347 20.6681 petromyzon_marinus ENSPMAP00000002565 77.8878 65.3465 ENSG00000083520 homo_sapiens ENSP00000366997 10.6472 8.45511 petromyzon_marinus ENSPMAP00000009854 82.9268 65.8537 ENSG00000083520 homo_sapiens ENSP00000366997 27.453 21.0856 petromyzon_marinus ENSPMAP00000010831 66.0804 50.7538 ENSG00000083520 homo_sapiens ENSP00000366997 31.524 25.1566 petromyzon_marinus ENSPMAP00000000828 73.6585 58.7805 ENSG00000083520 homo_sapiens ENSP00000366997 38.1002 32.3591 petromyzon_marinus ENSPMAP00000009819 81.4732 69.1964 ENSG00000083520 homo_sapiens ENSP00000366997 39.5616 33.0898 petromyzon_marinus ENSPMAP00000003905 71.6446 59.9244 ENSG00000083520 homo_sapiens ENSP00000366997 44.3633 36.4301 petromyzon_marinus ENSPMAP00000003060 71.4286 58.6555 ENSG00000083520 homo_sapiens ENSP00000366997 12.2129 8.87265 petromyzon_marinus ENSPMAP00000009976 64.6409 46.9613 ENSG00000083520 homo_sapiens ENSP00000366997 14.8225 11.1691 petromyzon_marinus ENSPMAP00000010134 62.8319 47.3451 ENSG00000083520 homo_sapiens ENSP00000366997 50.5219 39.2484 petromyzon_marinus ENSPMAP00000007840 66.2107 51.4364 ENSG00000083520 homo_sapiens ENSP00000366997 29.9582 25.4697 petromyzon_marinus ENSPMAP00000009908 75.9259 64.5503 ENSG00000083520 homo_sapiens ENSP00000366997 52.6096 41.7537 petromyzon_marinus ENSPMAP00000009966 72.3099 57.3888 ENSG00000083520 homo_sapiens ENSP00000366997 26.4092 20.5637 petromyzon_marinus ENSPMAP00000001668 65.8854 51.3021 ENSG00000083520 homo_sapiens ENSP00000366997 20.7724 15.5532 petromyzon_marinus ENSPMAP00000008017 63.7821 47.7564 ENSG00000083520 homo_sapiens ENSP00000366997 48.4342 38.5177 petromyzon_marinus ENSPMAP00000003572 66.6667 53.0172 ENSG00000083520 homo_sapiens ENSP00000366997 29.7495 24.8434 petromyzon_marinus ENSPMAP00000004403 77.027 64.3243 ENSG00000083520 homo_sapiens ENSP00000366997 25.9916 21.6075 petromyzon_marinus ENSPMAP00000009984 84.1216 69.9324 ENSG00000083520 homo_sapiens ENSP00000366997 17.6409 13.6743 petromyzon_marinus ENSPMAP00000001211 71.6102 55.5085 ENSG00000083520 homo_sapiens ENSP00000366997 53.4447 41.858 petromyzon_marinus ENSPMAP00000007048 67.8146 53.1126 ENSG00000083520 homo_sapiens ENSP00000366997 47.9123 37.2651 petromyzon_marinus ENSPMAP00000010391 74.6341 58.0488 ENSG00000083520 homo_sapiens ENSP00000366997 17.9541 13.8831 petromyzon_marinus ENSPMAP00000010214 68.254 52.7778 ENSG00000083520 homo_sapiens ENSP00000366997 10.4384 8.24635 petromyzon_marinus ENSPMAP00000004484 81.3008 64.2276 ENSG00000083520 homo_sapiens ENSP00000366997 11.691 8.5595 petromyzon_marinus ENSPMAP00000004091 69.1358 50.6173 ENSG00000083520 homo_sapiens ENSP00000366997 11.5866 8.5595 petromyzon_marinus ENSPMAP00000004572 68.0982 50.3067 ENSG00000083520 homo_sapiens ENSP00000366997 25.1566 18.6848 petromyzon_marinus ENSPMAP00000000911 64.7849 48.1183 ENSG00000083520 homo_sapiens ENSP00000366997 39.4572 31.9415 petromyzon_marinus ENSPMAP00000009780 67.9856 55.036 ENSG00000083520 homo_sapiens ENSP00000366997 27.6618 20.6681 eptatretus_burgeri ENSEBUP00000002559 80.0604 59.8187 ENSG00000083520 homo_sapiens ENSP00000366997 51.0438 41.9624 eptatretus_burgeri ENSEBUP00000016581 82.1849 67.563 ENSG00000083520 homo_sapiens ENSP00000366997 86.5344 74.1127 callorhinchus_milii ENSCMIP00000020753 83.4844 71.5005 ENSG00000083520 homo_sapiens ENSP00000366997 88.8309 78.0793 latimeria_chalumnae ENSLACP00000022307 88.7383 77.9979 ENSG00000083520 homo_sapiens ENSP00000366997 87.0564 75.8873 lepisosteus_oculatus ENSLOCP00000013918 87.6972 76.4458 ENSG00000083520 homo_sapiens ENSP00000366997 85.2818 72.8601 clupea_harengus ENSCHAP00000013862 86 73.4737 ENSG00000083520 homo_sapiens ENSP00000366997 86.7432 74.0084 danio_rerio ENSDARP00000079889 87.4737 74.6316 ENSG00000083520 homo_sapiens ENSP00000366997 85.9081 73.382 carassius_auratus ENSCARP00000023060 86.6316 74 ENSG00000083520 homo_sapiens ENSP00000366997 34.7599 29.0188 astyanax_mexicanus ENSAMXP00000054158 85.6041 71.4653 ENSG00000083520 homo_sapiens ENSP00000366997 81.9415 70.7724 astyanax_mexicanus ENSAMXP00000000577 88.9015 76.7837 ENSG00000083520 homo_sapiens ENSP00000366997 87.2651 74.8434 ictalurus_punctatus ENSIPUP00000033196 87.9075 75.3943 ENSG00000083520 homo_sapiens ENSP00000366997 86.3257 72.8601 esox_lucius ENSELUP00000059900 86.4159 72.9363 ENSG00000083520 homo_sapiens ENSP00000366997 86.5344 74.1127 electrophorus_electricus ENSEEEP00000010283 87.4473 74.8945 ENSG00000083520 homo_sapiens ENSP00000366997 84.5511 71.3988 oncorhynchus_kisutch ENSOKIP00005105013 85.8961 72.5345 ENSG00000083520 homo_sapiens ENSP00000366997 86.4301 72.8601 oncorhynchus_kisutch ENSOKIP00005072368 87.1579 73.4737 ENSG00000083520 homo_sapiens ENSP00000366997 82.4635 68.7891 oncorhynchus_mykiss ENSOMYP00000004478 79.397 66.2312 ENSG00000083520 homo_sapiens ENSP00000366997 85.1775 71.8163 oncorhynchus_mykiss ENSOMYP00000126002 81.6817 68.8689 ENSG00000083520 homo_sapiens ENSP00000366997 85.9081 72.9645 salmo_salar ENSSSAP00000118631 86.5405 73.5016 ENSG00000083520 homo_sapiens ENSP00000366997 86.0125 73.0689 salmo_salar ENSSSAP00000158477 86.8282 73.7619 ENSG00000083520 homo_sapiens ENSP00000366997 84.0292 71.2944 salmo_trutta ENSSTUP00000094460 84.117 71.3689 ENSG00000083520 homo_sapiens ENSP00000366997 86.0125 72.9645 salmo_trutta ENSSTUP00000077688 87.3807 74.1251 ENSG00000083520 homo_sapiens ENSP00000366997 85.1775 72.547 gadus_morhua ENSGMOP00000046783 80.7122 68.7438 ENSG00000083520 homo_sapiens ENSP00000366997 48.4342 40.1879 fundulus_heteroclitus ENSFHEP00000034185 84.5173 70.1275 ENSG00000083520 homo_sapiens ENSP00000366997 86.0125 72.0251 poecilia_reticulata ENSPREP00000016515 86.6456 72.5552 ENSG00000083520 homo_sapiens ENSP00000366997 85.595 72.0251 xiphophorus_maculatus ENSXMAP00000041318 86.225 72.5552 ENSG00000083520 homo_sapiens ENSP00000366997 85.3862 72.9645 oryzias_latipes ENSORLP00000006875 86.4693 73.8901 ENSG00000083520 homo_sapiens ENSP00000366997 86.2213 71.6075 cyclopterus_lumpus ENSCLMP00005044511 85.8628 71.3098 ENSG00000083520 homo_sapiens ENSP00000366997 85.6994 72.6514 oreochromis_niloticus ENSONIP00000032411 80.9665 68.6391 ENSG00000083520 homo_sapiens ENSP00000366997 86.4301 73.0689 haplochromis_burtoni ENSHBUP00000014630 87.1579 73.6842 ENSG00000083520 homo_sapiens ENSP00000366997 86.3257 73.0689 astatotilapia_calliptera ENSACLP00000026447 87.0526 73.6842 ENSG00000083520 homo_sapiens ENSP00000366997 86.6388 72.9645 sparus_aurata ENSSAUP00010004202 85.9213 72.3602 ENSG00000083520 homo_sapiens ENSP00000366997 86.5344 74.0084 lates_calcarifer ENSLCAP00010027805 83.6529 71.5439 ENSG00000083520 homo_sapiens ENSP00000366997 89.8747 79.1232 xenopus_tropicalis ENSXETP00000075647 86.4458 76.1044 ENSG00000083520 homo_sapiens ENSP00000366997 91.6493 82.881 chrysemys_picta_bellii ENSCPBP00000013905 85.3256 77.1623 ENSG00000083520 homo_sapiens ENSP00000366997 87.1608 77.8706 sphenodon_punctatus ENSSPUP00000015322 89.8816 80.3014 ENSG00000083520 homo_sapiens ENSP00000366997 91.4405 82.2547 crocodylus_porosus ENSCPRP00005026977 91.25 82.0833 ENSG00000083520 homo_sapiens ENSP00000366997 88.9353 79.8539 laticauda_laticaudata ENSLLTP00000017037 88.9353 79.8539 ENSG00000083520 homo_sapiens ENSP00000366997 87.6827 79.1232 notechis_scutatus ENSNSUP00000013398 86.4198 77.9835 ENSG00000083520 homo_sapiens ENSP00000366997 87.7871 78.6012 pseudonaja_textilis ENSPTXP00000005444 86.701 77.6289 ENSG00000083520 homo_sapiens ENSP00000366997 92.0668 82.6722 anas_platyrhynchos_platyrhynchos ENSAPLP00000012470 91.7794 82.4142 ENSG00000083520 homo_sapiens ENSP00000366997 86.7432 78.1837 gallus_gallus ENSGALP00010001031 89.8378 80.973 ENSG00000083520 homo_sapiens ENSP00000366997 46.0334 41.7537 meleagris_gallopavo ENSMGAP00000024787 90 81.6327 ENSG00000083520 homo_sapiens ENSP00000366997 85.6994 76.7223 serinus_canaria ENSSCAP00000021014 90.2198 80.7692 ENSG00000083520 homo_sapiens ENSP00000366997 91.5449 81.8372 parus_major ENSPMJP00000018244 90.9751 81.3278 ENSG00000083520 homo_sapiens ENSP00000366997 91.5449 81.8372 anolis_carolinensis ENSACAP00000000706 83.2859 74.4539 ENSG00000083520 homo_sapiens ENSP00000366997 85.3862 72.1294 neolamprologus_brichardi ENSNBRP00000020582 86.8365 73.3546 ENSG00000083520 homo_sapiens ENSP00000366997 81.0021 71.2944 naja_naja ENSNNAP00000023058 83.8013 73.7581 ENSG00000083520 homo_sapiens ENSP00000366997 92.1712 82.0459 podarcis_muralis ENSPMRP00000012308 91.219 81.1983 ENSG00000083520 homo_sapiens ENSP00000366997 85.8038 76.8267 geospiza_fortis ENSGFOP00000014841 89.5425 80.1743 ENSG00000083520 homo_sapiens ENSP00000366997 91.1273 81.1065 taeniopygia_guttata ENSTGUP00000012874 90.6542 80.6854 ENSG00000083520 homo_sapiens ENSP00000366997 49.8956 43.215 erpetoichthys_calabaricus ENSECRP00000026545 88.5185 76.6667 ENSG00000083520 homo_sapiens ENSP00000366997 84.8643 72.1294 kryptolebias_marmoratus ENSKMAP00000000461 86.0317 73.1217 ENSG00000083520 homo_sapiens ENSP00000366997 91.3361 81.524 salvator_merianae ENSSMRP00000023535 90.0206 80.3498 ENSG00000083520 homo_sapiens ENSP00000366997 86.0125 72.1294 oryzias_javanicus ENSOJAP00000017323 86.8282 72.8135 ENSG00000083520 homo_sapiens ENSP00000366997 83.4029 69.6242 amphilophus_citrinellus ENSACIP00000007767 83.9286 70.063 ENSG00000083520 homo_sapiens ENSP00000366997 85.1775 70.9812 dicentrarchus_labrax ENSDLAP00005014664 85.5346 71.2788 ENSG00000083520 homo_sapiens ENSP00000366997 86.3257 73.6952 amphiprion_percula ENSAPEP00000009229 86.9611 74.2376 ENSG00000083520 homo_sapiens ENSP00000366997 85.2818 72.7557 oryzias_sinensis ENSOSIP00000043971 84.9272 72.4532 ENSG00000083520 homo_sapiens ENSP00000366997 91.3361 82.1503 pelodiscus_sinensis ENSPSIP00000004248 78.7579 70.8371 ENSG00000083520 homo_sapiens ENSP00000366997 85.4906 76.7223 gopherus_evgoodei ENSGEVP00005000888 90.3974 81.1258 ENSG00000083520 homo_sapiens ENSP00000366997 91.5449 82.9854 chelonoidis_abingdonii ENSCABP00000028909 91.4494 82.8988 ENSG00000083520 homo_sapiens ENSP00000366997 86.5344 73.2777 seriola_dumerili ENSSDUP00000024345 87.1714 73.817 ENSG00000083520 homo_sapiens ENSP00000366997 85.2818 72.4426 cottoperca_gobio ENSCGOP00000053554 84.2268 71.5464 ENSG00000083520 homo_sapiens ENSP00000366997 87.8914 78.2881 struthio_camelus_australis ENSSCUP00000015163 87.3444 77.8008 ENSG00000083520 homo_sapiens ENSP00000366997 91.858 83.0898 anser_brachyrhynchus ENSABRP00000000009 91.5713 82.8304 ENSG00000083520 homo_sapiens ENSP00000366997 85.0731 70.7724 gasterosteus_aculeatus ENSGACP00000013016 83.7616 69.6814 ENSG00000083520 homo_sapiens ENSP00000366997 86.1169 73.0689 cynoglossus_semilaevis ENSCSEP00000004687 87.0253 73.8397 ENSG00000083520 homo_sapiens ENSP00000366997 86.0125 72.547 poecilia_formosa ENSPFOP00000018192 86.6456 73.081 ENSG00000083520 homo_sapiens ENSP00000366997 86.2213 73.6952 myripristis_murdjan ENSMMDP00005004380 83.6879 71.5299 ENSG00000083520 homo_sapiens ENSP00000366997 86.2213 72.3382 sander_lucioperca ENSSLUP00000057537 86.6737 72.7177 ENSG00000083520 homo_sapiens ENSP00000366997 85.1775 76.7223 strigops_habroptila ENSSHBP00005004140 90.0662 81.1258 ENSG00000083520 homo_sapiens ENSP00000366997 86.5344 73.7996 amphiprion_ocellaris ENSAOCP00000010124 87.1714 74.3428 ENSG00000083520 homo_sapiens ENSP00000366997 91.9624 83.1942 terrapene_carolina_triunguis ENSTMTP00000021687 91.8665 83.1074 ENSG00000083520 homo_sapiens ENSP00000366997 60.5428 50.8351 hucho_hucho ENSHHUP00000049827 83.3333 69.9713 ENSG00000083520 homo_sapiens ENSP00000366997 8.45511 6.68058 hucho_hucho ENSHHUP00000026575 87.0968 68.8172 ENSG00000083520 homo_sapiens ENSP00000366997 84.9687 71.5031 betta_splendens ENSBSLP00000033208 83.4872 70.2564 ENSG00000083520 homo_sapiens ENSP00000366997 87.0564 74.4259 pygocentrus_nattereri ENSPNAP00000026072 87.6972 74.9737 ENSG00000083520 homo_sapiens ENSP00000366997 86.6388 73.4864 anabas_testudineus ENSATEP00000070754 84.0932 71.3273 ENSG00000083520 homo_sapiens ENSP00000366997 66.5971 53.5491 ciona_savignyi ENSCSAVP00000000868 77.4272 62.2573 ENSG00000083520 homo_sapiens ENSP00000366997 63.8831 44.6764 saccharomyces_cerevisiae YOL021C 61.1389 42.7572 ENSG00000083520 homo_sapiens ENSP00000366997 86.5344 73.382 seriola_lalandi_dorsalis ENSSLDP00000019328 87.1714 73.9222 ENSG00000083520 homo_sapiens ENSP00000366997 85.9081 72.547 labrus_bergylta ENSLBEP00000028583 86.4496 73.0042 ENSG00000083520 homo_sapiens ENSP00000366997 86.4301 73.0689 pundamilia_nyererei ENSPNYP00000004482 84.9231 71.7949 ENSG00000083520 homo_sapiens ENSP00000366997 85.4906 72.547 mastacembelus_armatus ENSMAMP00000024922 77.704 65.9393 ENSG00000083520 homo_sapiens ENSP00000366997 86.5344 72.7557 stegastes_partitus ENSSPAP00000025905 87.1714 73.2913 ENSG00000083520 homo_sapiens ENSP00000366997 31.0021 24.8434 oncorhynchus_tshawytscha ENSOTSP00005099733 82.7298 66.2953 ENSG00000083520 homo_sapiens ENSP00000366997 86.2213 73.4864 acanthochromis_polyacanthus ENSAPOP00000021967 86.8559 74.0273 ENSG00000083520 homo_sapiens ENSP00000366997 91.4405 82.2547 aquila_chrysaetos_chrysaetos ENSACCP00020021546 91.0603 81.9127 ENSG00000083520 homo_sapiens ENSP00000366997 86.1169 72.3382 nothobranchius_furzeri ENSNFUP00015053112 86.2971 72.4895 ENSG00000083520 homo_sapiens ENSP00000366997 86.2213 72.3382 cyprinodon_variegatus ENSCVAP00000030509 86.8559 72.8707 ENSG00000083520 homo_sapiens ENSP00000366997 84.9687 72.9645 denticeps_clupeoides ENSDCDP00000035765 84.7917 72.8125 ENSG00000083520 homo_sapiens ENSP00000366997 86.3257 72.9645 larimichthys_crocea ENSLCRP00005056453 86.1458 72.8125 ENSG00000083520 homo_sapiens ENSP00000366997 84.3424 70.8768 takifugu_rubripes ENSTRUP00000025214 84.7849 71.2487 ENSG00000083520 homo_sapiens ENSP00000366997 88.309 78.81 ficedula_albicollis ENSFALP00000032878 73.7576 65.8239 ENSG00000083520 homo_sapiens ENSP00000366997 80.3758 68.1628 hippocampus_comes ENSHCOP00000026586 85.8417 72.7982 ENSG00000083520 homo_sapiens ENSP00000366997 49.0605 41.1273 hippocampus_comes ENSHCOP00000026620 83.779 70.2317 ENSG00000083520 homo_sapiens ENSP00000366997 79.7495 68.1628 cyprinus_carpio_carpio ENSCCRP00000013614 82.8633 70.8243 ENSG00000083520 homo_sapiens ENSP00000366997 85.8038 72.9645 cyprinus_carpio_carpio ENSCCRP00000060885 83.2827 70.8207 ENSG00000083520 homo_sapiens ENSP00000366997 90.3967 80.5845 coturnix_japonica ENSCJPP00005024895 89.9273 80.1661 ENSG00000083520 homo_sapiens ENSP00000366997 85.6994 72.4426 poecilia_latipinna ENSPLAP00000022587 86.8783 73.4392 ENSG00000083520 homo_sapiens ENSP00000366997 84.238 71.8163 sinocyclocheilus_grahami ENSSGRP00000049352 84.5026 72.0419 ENSG00000083520 homo_sapiens ENSP00000366997 86.3257 73.0689 maylandia_zebra ENSMZEP00005036817 87.0526 73.6842 ENSG00000083520 homo_sapiens ENSP00000366997 85.6994 71.2944 tetraodon_nigroviridis ENSTNIP00000020164 86.6948 72.1225 ENSG00000083520 homo_sapiens ENSP00000366997 78.3925 65.0313 paramormyrops_kingsleyae ENSPKIP00000034680 85.438 70.876 ENSG00000083520 homo_sapiens ENSP00000366997 85.4906 72.9645 scleropages_formosus ENSSFOP00015010633 85.4015 72.8884 ENSG00000083520 homo_sapiens ENSP00000366997 8.5595 7.09812 leptobrachium_leishanense ENSLLEP00000039997 75.9259 62.963 ENSG00000083520 homo_sapiens ENSP00000366997 85.595 72.6514 scophthalmus_maximus ENSSMAP00000060628 84.1026 71.3846 ENSG00000083520 homo_sapiens ENSP00000366997 85.9081 72.547 oryzias_melastigma ENSOMEP00000008089 86.8143 73.3122
Go ID
Go term
No. evidence
Entries
Species
Category
GO:0000175 enables 3-5-RNA exonuclease activity 3 IBA,IMP,TAS Homo_sapiens(9606) Function GO:0000176 part_of nuclear exosome (RNase complex) 3 IBA,IDA,NAS Homo_sapiens(9606) Component GO:0000177 part_of cytoplasmic exosome (RNase complex) 1 IBA Homo_sapiens(9606) Component GO:0000178 part_of exosome (RNase complex) 2 NAS,TAS Homo_sapiens(9606) Component GO:0003723 enables RNA binding 1 IEA Homo_sapiens(9606) Function GO:0004519 enables endonuclease activity 2 IBA,IMP Homo_sapiens(9606) Function GO:0005085 enables guanyl-nucleotide exchange factor activity 1 IDA Homo_sapiens(9606) Function GO:0005515 enables protein binding 1 IPI Homo_sapiens(9606) Function GO:0005634 located_in nucleus 1 IDA Homo_sapiens(9606) Component GO:0005654 located_in nucleoplasm 1 IDA Homo_sapiens(9606) Component GO:0005730 NOT located_in nucleolus 1 IDA Homo_sapiens(9606) Component GO:0005829 located_in cytosol 2 IDA,TAS Homo_sapiens(9606) Component GO:0006364 involved_in rRNA processing 1 TAS Homo_sapiens(9606) Process GO:0006396 involved_in RNA processing 1 IDA Homo_sapiens(9606) Process GO:0006401 involved_in RNA catabolic process 1 IDA Homo_sapiens(9606) Process GO:0016020 located_in membrane 1 HDA Homo_sapiens(9606) Component GO:0016075 involved_in rRNA catabolic process 2 IBA,IMP Homo_sapiens(9606) Process GO:0043928 involved_in exonucleolytic catabolism of deadenylated mRNA 1 TAS Homo_sapiens(9606) Process GO:0071034 involved_in CUT catabolic process 1 IMP Homo_sapiens(9606) Process
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