Functions and Diseases

RBP Type Canonical_RBPs
Diseases Cancer
Drug N.A.
Main interacting RNAs N.A.
Moonlighting functions Transmemebrane
Localizations N.A.
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000081177 Gene ID 55218 Accession 20217
Symbol EXD2 Alias EXDL2;C14orf114 Full Name exonuclease 3'-5' domain containing 2
Status Confidence Length 52523 bases Strand Plus strand
Position 14 : 69191498 - 69244020 RNA binding domain DNA_pol_A_exo1
Summary Enables 3'-5' exonuclease activity; metal ion binding activity; and protein homodimerization activity. Involved in nucleic acid metabolic process. Located in intermediate filament cytoskeleton; mitochondrial outer membrane; and site of DNA damage. [provided by Alliance of Genome Resources, Apr 2022]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000313140 DNA_pol_A_exo1 PF01612 1.7e-16 1
ENSP00000387331 DNA_pol_A_exo1 PF01612 1.7e-16 1
ENSP00000510642 DNA_pol_A_exo1 PF01612 1.7e-16 1
ENSP00000386632 DNA_pol_A_exo1 PF01612 1.5e-13 1
ENSP00000386762 DNA_pol_A_exo1 PF01612 1.5e-13 1
ENSP00000386839 DNA_pol_A_exo1 PF01612 1.5e-13 1
ENSP00000386915 DNA_pol_A_exo1 PF01612 1.5e-13 1
ENSP00000508828 DNA_pol_A_exo1 PF01612 8.9e-11 1
ENSP00000409089 DNA_pol_A_exo1 PF01612 3.4e-08 1

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
34404792 Spatiotemporally-resolved mapping of RNA binding proteins via functional proximity labeling reveals a mitochondrial mRNA anchor promoting stress recovery. Wei Qin 2021-08-17 Nature communications
36326837 Discrete RNA-DNA hybrid cleavage by the EXD2 exonuclease pinpoints two rate-limiting steps. Xinshuo Jia 2023-01-04 The EMBO journal

Transcripts

Name Transcript ID bp Protein Translation ID
EXD2-214 ENST00000685843 5009 621aa ENSP00000510642
EXD2-203 ENST00000409018 3252 621aa ENSP00000387331
EXD2-212 ENST00000492815 3243 247aa ENSP00000508828
EXD2-202 ENST00000409014 3404 496aa ENSP00000386915
EXD2-210 ENST00000487724 544 No protein -
EXD2-205 ENST00000409675 2828 496aa ENSP00000386762
EXD2-206 ENST00000409949 2688 496aa ENSP00000386632
EXD2-201 ENST00000312994 5107 621aa ENSP00000313140
EXD2-204 ENST00000409242 2496 496aa ENSP00000386839
EXD2-208 ENST00000461908 579 No protein -
EXD2-207 ENST00000413191 1143 114aa ENSP00000409089
EXD2-211 ENST00000489133 521 No protein -
EXD2-213 ENST00000494629 493 No protein -
EXD2-209 ENST00000465286 678 No protein -

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
175Parkinson Disease5.752E-517052657
244Parkinson Disease2.750898E-517052657

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000081177homo_sapiensENSP0000034047421.803712.4429homo_sapiensENSP0000051064230.756817.5523

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000081177homo_sapiensENSP0000051064299.677999.0338nomascus_leucogenysENSNLEP0000000157399.677999.0338
ENSG00000081177homo_sapiensENSP0000051064299.677999.3559pan_paniscusENSPPAP0000003915399.677999.3559
ENSG00000081177homo_sapiensENSP0000051064299.194898.7118pongo_abeliiENSPPYP0000000675199.194898.7118
ENSG00000081177homo_sapiensENSP0000051064299.677999.5169pan_troglodytesENSPTRP0000008016699.677999.5169
ENSG00000081177homo_sapiensENSP0000051064299.516999.1948gorilla_gorillaENSGGOP0000000124499.516999.1948
ENSG00000081177homo_sapiensENSP0000051064281.320470.6924ornithorhynchus_anatinusENSOANP0000003750378.052667.8516
ENSG00000081177homo_sapiensENSP0000051064282.930872.6248sarcophilus_harrisiiENSSHAP0000000573583.064572.7419
ENSG00000081177homo_sapiensENSP0000051064254.911448.9533notamacropus_eugeniiENSMEUP0000000385268.7561.2903
ENSG00000081177homo_sapiensENSP0000051064248.148146.2158choloepus_hoffmanniENSCHOP0000000298373.284370.3431
ENSG00000081177homo_sapiensENSP0000051064293.236786.9565dasypus_novemcinctusENSDNOP0000002932093.387187.0968
ENSG00000081177homo_sapiensENSP0000051064276.811672.6248erinaceus_europaeusENSEEUP0000000638096.169490.9274
ENSG00000081177homo_sapiensENSP0000051064273.75269.7262echinops_telfairiENSETEP0000001119992.338787.2984
ENSG00000081177homo_sapiensENSP0000051064298.711897.4235callithrix_jacchusENSCJAP0000002762898.711897.4235
ENSG00000081177homo_sapiensENSP0000051064298.711897.5845cercocebus_atysENSCATP0000001249198.87197.7419
ENSG00000081177homo_sapiensENSP0000051064298.711897.5845macaca_fascicularisENSMFAP0000004134798.87197.7419
ENSG00000081177homo_sapiensENSP0000051064298.389797.1014macaca_mulattaENSMMUP0000002701698.548497.2581
ENSG00000081177homo_sapiensENSP0000051064298.711897.5845macaca_nemestrinaENSMNEP0000003022898.87197.7419
ENSG00000081177homo_sapiensENSP0000051064298.872897.7456papio_anubisENSPANP0000001714399.032397.9032
ENSG00000081177homo_sapiensENSP0000051064298.872897.7456mandrillus_leucophaeusENSMLEP0000004023199.032397.9032
ENSG00000081177homo_sapiensENSP0000051064276.489574.0741tursiops_truncatusENSTTRP0000001322995.766192.7419
ENSG00000081177homo_sapiensENSP0000051064294.52590.1771vulpes_vulpesENSVVUP0000000469193.7789.4569
ENSG00000081177homo_sapiensENSP0000051064292.753685.6683mus_spretusMGP_SPRETEiJ_P003417089.302382.4806
ENSG00000081177homo_sapiensENSP0000051064294.202989.372equus_asinusENSEASP0000502442294.051489.2283
ENSG00000081177homo_sapiensENSP0000051064294.68690.0161capra_hircusENSCHIP0000002493291.588887.0716
ENSG00000081177homo_sapiensENSP0000051064293.236789.211loxodonta_africanaENSLAFP0000001595293.53889.4992
ENSG00000081177homo_sapiensENSP0000051064294.202988.4058panthera_leoENSPLOP0000002149094.202988.4058
ENSG00000081177homo_sapiensENSP0000051064293.880888.4058ailuropoda_melanoleucaENSAMEP0000001526393.2887.84
ENSG00000081177homo_sapiensENSP0000051064293.397789.0499bos_indicus_hybridENSBIXP0000502792492.209987.9173
ENSG00000081177homo_sapiensENSP0000051064291.948587.1176oryctolagus_cuniculusENSOCUP0000000572488.802584.1369
ENSG00000081177homo_sapiensENSP0000051064294.041989.372equus_caballusENSECAP0000008374788.084583.7104
ENSG00000081177homo_sapiensENSP0000051064294.363989.694canis_lupus_familiarisENSCAFP0084500570993.610288.9776
ENSG00000081177homo_sapiensENSP0000051064293.719888.0837panthera_pardusENSPPRP0000000792293.719888.0837
ENSG00000081177homo_sapiensENSP0000051064294.041990.3382marmota_marmota_marmotaENSMMMP0000000068893.4489.76
ENSG00000081177homo_sapiensENSP0000051064293.719889.8551balaenoptera_musculusENSBMSP0001000283893.569189.7106
ENSG00000081177homo_sapiensENSP0000051064291.626485.8293cavia_porcellusENSCPOP0000000899291.922586.1066
ENSG00000081177homo_sapiensENSP0000051064294.202988.4058felis_catusENSFCAP0000001665094.202988.4058
ENSG00000081177homo_sapiensENSP0000051064294.363989.211ursus_americanusENSUAMP0000001340193.910388.7821
ENSG00000081177homo_sapiensENSP0000051064281.803568.9211monodelphis_domesticaENSMODP0000001281081.150268.3706
ENSG00000081177homo_sapiensENSP0000051064294.363990.4992bison_bison_bisonENSBBBP0000002781094.668890.7916
ENSG00000081177homo_sapiensENSP0000051064293.558889.8551monodon_monocerosENSMMNP0001501798693.258489.5666
ENSG00000081177homo_sapiensENSP0000051064292.914788.5668sus_scrofaENSSSCP0000003762186.766982.7068
ENSG00000081177homo_sapiensENSP0000051064287.278683.4138microcebus_murinusENSMICP0000000873586.443482.6156
ENSG00000081177homo_sapiensENSP0000051064291.787485.8293octodon_degusENSODEP0000001930891.935585.9677
ENSG00000081177homo_sapiensENSP0000051064226.40924.6377jaculus_jaculusENSJJAP0000000023893.714387.4286
ENSG00000081177homo_sapiensENSP0000051064262.640957.649jaculus_jaculusENSJJAP0000002086889.425382.2989
ENSG00000081177homo_sapiensENSP0000051064276.972674.3961ovis_aries_rambouilletENSOARP0002000497496.37193.1452
ENSG00000081177homo_sapiensENSP0000051064294.202989.0499ursus_maritimusENSUMAP0000001370693.7588.6218
ENSG00000081177homo_sapiensENSP0000051064276.167572.6248ochotona_princepsENSOPRP0000000007295.362990.9274
ENSG00000081177homo_sapiensENSP0000051064293.558889.8551delphinapterus_leucasENSDLEP0000001545293.258489.5666
ENSG00000081177homo_sapiensENSP0000051064293.880889.694physeter_catodonENSPCTP0000502243493.429589.2628
ENSG00000081177homo_sapiensENSP0000051064292.592685.8293mus_caroliMGP_CAROLIEiJ_P003266189.009382.5077
ENSG00000081177homo_sapiensENSP0000051064292.914785.8293mus_musculusENSMUSP0000004304988.769282
ENSG00000081177homo_sapiensENSP0000051064291.626487.1176dipodomys_ordiiENSDORP0000001420090.174385.7369
ENSG00000081177homo_sapiensENSP0000051064293.236789.0499mustela_putorius_furoENSMPUP0000000731093.086888.9068
ENSG00000081177homo_sapiensENSP0000051064298.228796.6184aotus_nancymaaeENSANAP0000001217798.228796.6184
ENSG00000081177homo_sapiensENSP0000051064298.711897.4235saimiri_boliviensis_boliviensisENSSBOP0000003817798.711897.4235
ENSG00000081177homo_sapiensENSP0000051064265.861563.285vicugna_pacosENSVPAP0000000525796.462392.6887
ENSG00000081177homo_sapiensENSP0000051064298.872897.5845chlorocebus_sabaeusENSCSAP0000000926096.540995.283
ENSG00000081177homo_sapiensENSP0000051064253.945352.3349tupaia_belangeriENSTBEP0000000166473.951471.7439
ENSG00000081177homo_sapiensENSP0000051064227.053125.9259mesocricetus_auratusENSMAUP000000247299692
ENSG00000081177homo_sapiensENSP0000051064294.041990.6602phocoena_sinusENSPSNP0000001133193.7490.3692
ENSG00000081177homo_sapiensENSP0000051064294.363989.694camelus_dromedariusENSCDRP0000500460093.163788.5533
ENSG00000081177homo_sapiensENSP0000051064292.109587.2786carlito_syrichtaENSTSYP0000000203992.258187.4194
ENSG00000081177homo_sapiensENSP0000051064293.719888.0837panthera_tigris_altaicaENSPTIP0000002187993.719888.0837
ENSG00000081177homo_sapiensENSP0000051064293.558885.9903rattus_norvegicusENSRNOP0000003086289.938182.6625
ENSG00000081177homo_sapiensENSP0000051064296.296393.2367prolemur_simusENSPSMP0000003367096.296393.2367
ENSG00000081177homo_sapiensENSP0000051064292.270584.219microtus_ochrogasterENSMOCP0000002247190.094382.2327
ENSG00000081177homo_sapiensENSP0000051064265.056460.7085sorex_araneusENSSARP0000001150981.451676.0081
ENSG00000081177homo_sapiensENSP0000051064290.821384.219peromyscus_maniculatus_bairdiiENSPEMP0000000282087.850581.4642
ENSG00000081177homo_sapiensENSP0000051064294.363990.0161bos_mutusENSBMUP0000001716193.460989.1547
ENSG00000081177homo_sapiensENSP0000051064292.753685.6683mus_spicilegusENSMSIP0000001853289.164182.3529
ENSG00000081177homo_sapiensENSP0000051064292.753686.3124cricetulus_griseus_chok1gshdENSCGRP0000102404788.208382.0827
ENSG00000081177homo_sapiensENSP0000051064276.650674.0741pteropus_vampyrusENSPVAP0000001594196.161692.9293
ENSG00000081177homo_sapiensENSP0000051064279.227176.0064myotis_lucifugusENSMLUP0000001078996.470692.549
ENSG00000081177homo_sapiensENSP0000051064293.880888.8889rhinolophus_ferrumequinumENSRFEP0001000709892.39387.4802
ENSG00000081177homo_sapiensENSP0000051064292.753688.2448neovison_visonENSNVIP0000001248792.455987.9615
ENSG00000081177homo_sapiensENSP0000051064294.363990.1771bos_taurusENSBTAP0000001325593.312189.172
ENSG00000081177homo_sapiensENSP0000051064291.948586.1514heterocephalus_glaber_femaleENSHGLP0000005096391.068685.327
ENSG00000081177homo_sapiensENSP0000051064298.872898.0676rhinopithecus_bietiENSRBIP0000001405398.872898.0676
ENSG00000081177homo_sapiensENSP0000051064294.363989.694canis_lupus_dingoENSCAFP0002000726494.06189.4061
ENSG00000081177homo_sapiensENSP0000051064294.041989.8551sciurus_vulgarisENSSVLP0000501588093.290789.1374
ENSG00000081177homo_sapiensENSP0000051064267.793957.3269phascolarctos_cinereusENSPCIP0000004946376.268164.4928
ENSG00000081177homo_sapiensENSP0000051064276.006472.7858procavia_capensisENSPCAP0000000675295.161391.129
ENSG00000081177homo_sapiensENSP0000051064227.214225.7649nannospalax_galiliENSNGAP0000001058996.571491.4286
ENSG00000081177homo_sapiensENSP0000051064294.52590.4992bos_grunniensENSBGRP0000001153094.830490.7916
ENSG00000081177homo_sapiensENSP0000051064291.465485.9903chinchilla_lanigeraENSCLAP0000000806292.058386.5478
ENSG00000081177homo_sapiensENSP0000051064293.719889.8551cervus_hanglu_yarkandensisENSCHYP0000002139393.269289.4231
ENSG00000081177homo_sapiensENSP0000051064291.787488.5668catagonus_wagneriENSCWAP0000002951091.346288.141
ENSG00000081177homo_sapiensENSP0000051064294.84791.3043ictidomys_tridecemlineatusENSSTOP0000000015493.343989.8574
ENSG00000081177homo_sapiensENSP0000051064296.135390.6602otolemur_garnettiiENSOGAP0000001078895.5290.08
ENSG00000081177homo_sapiensENSP0000051064298.067696.7794cebus_imitatorENSCCAP0000002832398.067696.7794
ENSG00000081177homo_sapiensENSP0000051064295.00891.1433urocitellus_parryiiENSUPAP0001001552193.650889.8413
ENSG00000081177homo_sapiensENSP0000051064293.719889.211moschus_moschiferusENSMMSP0000002019593.269288.7821
ENSG00000081177homo_sapiensENSP0000051064298.872898.0676rhinopithecus_roxellanaENSRROP0000001839098.872898.0676
ENSG00000081177homo_sapiensENSP0000051064292.270584.058mus_pahariMGP_PahariEiJ_P008277189.952981.9466
ENSG00000081177homo_sapiensENSP0000051064295.491192.5926propithecus_coquereliENSPCOP0000003185095.491192.5926
ENSG00000081177homo_sapiensENSP0000051064254.267335.9098drosophila_melanogasterFBpp008187857.804538.2504
ENSG00000081177homo_sapiensENSP0000051064256.038638.1642ciona_intestinalisENSCINP0000002853460.73341.3613
ENSG00000081177homo_sapiensENSP0000051064244.283433.6554petromyzon_marinusENSPMAP0000000729864.252348.8318
ENSG00000081177homo_sapiensENSP0000051064251.529838.8084eptatretus_burgeriENSEBUP0000002148355.749141.9861
ENSG00000081177homo_sapiensENSP0000051064272.302758.9372callorhinchus_miliiENSCMIP0000004366472.889659.4156
ENSG00000081177homo_sapiensENSP0000051064273.107958.132latimeria_chalumnaeENSLACP0000002118273.581858.5089
ENSG00000081177homo_sapiensENSP0000051064276.006459.2593lepisosteus_oculatusENSLOCP0000001648776.998460.0326
ENSG00000081177homo_sapiensENSP0000051064270.531454.7504clupea_harengusENSCHAP0000003927062.482248.5021
ENSG00000081177homo_sapiensENSP0000051064271.980754.5894danio_rerioENSDARP0000009887572.447354.9433
ENSG00000081177homo_sapiensENSP0000051064272.141754.5894carassius_auratusENSCARP0000001555072.609454.9433
ENSG00000081177homo_sapiensENSP0000051064271.175555.7166astyanax_mexicanusENSAMXP0000004350368.847453.8941
ENSG00000081177homo_sapiensENSP0000051064271.819657.1659ictalurus_punctatusENSIPUP0000000077770.681556.2599
ENSG00000081177homo_sapiensENSP0000051064270.853554.9114esox_luciusENSELUP0000002343366.666751.6667
ENSG00000081177homo_sapiensENSP0000051064268.115954.1063electrophorus_electricusENSEEEP0000000251768.668854.5455
ENSG00000081177homo_sapiensENSP0000051064271.336655.8776oncorhynchus_kisutchENSOKIP0000501275867.325252.7356
ENSG00000081177homo_sapiensENSP0000051064270.048353.9453oncorhynchus_kisutchENSOKIP0000500439468.938253.0903
ENSG00000081177homo_sapiensENSP0000051064269.404254.9114oncorhynchus_mykissENSOMYP0000001489165.902152.1407
ENSG00000081177homo_sapiensENSP0000051064271.175555.7166oncorhynchus_mykissENSOMYP0000013529567.173352.5836
ENSG00000081177homo_sapiensENSP0000051064271.497655.8776salmo_salarENSSSAP0000002236667.682952.8963
ENSG00000081177homo_sapiensENSP0000051064271.497655.0725salmo_salarENSSSAP0000014512572.077955.5195
ENSG00000081177homo_sapiensENSP0000051064271.819656.0386salmo_truttaENSSTUP0000003770267.067752.3308
ENSG00000081177homo_sapiensENSP0000051064270.370454.4283salmo_truttaENSSTUP0000008502866.312651.2898
ENSG00000081177homo_sapiensENSP0000051064268.43853.1401gadus_morhuaENSGMOP0000000631165.789551.0836
ENSG00000081177homo_sapiensENSP0000051064271.014554.9114fundulus_heteroclitusENSFHEP0000000926269.014153.3646
ENSG00000081177homo_sapiensENSP0000051064272.141755.3945poecilia_reticulataENSPREP0000001254469.565253.4161
ENSG00000081177homo_sapiensENSP0000051064272.463855.8776xiphophorus_maculatusENSXMAP0000000357470.422554.3036
ENSG00000081177homo_sapiensENSP0000051064270.853554.5894oryzias_latipesENSORLP0000002458670.62654.4141
ENSG00000081177homo_sapiensENSP0000051064271.658656.1997cyclopterus_lumpusENSCLMP0000503778669.206854.2768
ENSG00000081177homo_sapiensENSP0000051064270.370454.7504oreochromis_niloticusENSONIP0000000048668.281253.125
ENSG00000081177homo_sapiensENSP0000051064270.209355.0725haplochromis_burtoniENSHBUP0000001734468.661453.8583
ENSG00000081177homo_sapiensENSP0000051064270.048354.5894astatotilapia_callipteraENSACLP0000000059267.968852.9688
ENSG00000081177homo_sapiensENSP0000051064272.302757.0048sparus_aurataENSSAUP0001004975869.937755.1402
ENSG00000081177homo_sapiensENSP0000051064271.175556.3607lates_calcariferENSLCAP0001002132869.170654.7731
ENSG00000081177homo_sapiensENSP0000051064275.201360.8696xenopus_tropicalisENSXETP0000010505270.120156.7568
ENSG00000081177homo_sapiensENSP0000051064283.574971.0145chrysemys_picta_belliiENSCPBP0000003068983.574971.0145
ENSG00000081177homo_sapiensENSP0000051064270.531459.0982sphenodon_punctatusENSSPUP0000000283986.904872.8175
ENSG00000081177homo_sapiensENSP0000051064281.642568.9211crocodylus_porosusENSCPRP0000502615481.906369.1438
ENSG00000081177homo_sapiensENSP0000051064224.154621.4171laticauda_laticaudataENSLLTP0000000260285.714376
ENSG00000081177homo_sapiensENSP0000051064276.972663.285notechis_scutatusENSNSUP0000002444075.275661.8898
ENSG00000081177homo_sapiensENSP0000051064276.811663.285pseudonaja_textilisENSPTXP0000001759877.687364.0065
ENSG00000081177homo_sapiensENSP0000051064280.515368.599anas_platyrhynchos_platyrhynchosENSAPLP0000003212265.18955.5411
ENSG00000081177homo_sapiensENSP0000051064280.515368.438gallus_gallusENSGALP0001002897380.515368.438
ENSG00000081177homo_sapiensENSP0000051064271.175561.6747meleagris_gallopavoENSMGAP0000001245783.87172.6755
ENSG00000081177homo_sapiensENSP0000051064280.676369.5652serinus_canariaENSSCAP0000001830880.676369.5652
ENSG00000081177homo_sapiensENSP0000051064280.515368.438parus_majorENSPMJP0000002020177.519465.8915
ENSG00000081177homo_sapiensENSP0000051064276.972663.285anolis_carolinensisENSACAP0000000520877.221363.4895
ENSG00000081177homo_sapiensENSP0000051064270.370455.0725neolamprologus_brichardiENSNBRP0000000593168.818953.8583
ENSG00000081177homo_sapiensENSP0000051064276.328563.4461naja_najaENSNNAP0000001892077.198764.1694
ENSG00000081177homo_sapiensENSP0000051064276.489563.124podarcis_muralisENSPMRP0000000525373.189560.4006
ENSG00000081177homo_sapiensENSP0000051064279.388167.9549geospiza_fortisENSGFOP0000001248480.952469.2939
ENSG00000081177homo_sapiensENSP0000051064280.032268.599taeniopygia_guttataENSTGUP0000001182278.763967.5119
ENSG00000081177homo_sapiensENSP0000051064274.074157.971erpetoichthys_calabaricusENSECRP0000002534276.41259.8007
ENSG00000081177homo_sapiensENSP0000051064271.980755.8776kryptolebias_marmoratusENSKMAP0000002260169.95354.3036
ENSG00000081177homo_sapiensENSP0000051064278.260964.4122salvator_merianaeENSSMRP0000001229878.640864.7249
ENSG00000081177homo_sapiensENSP0000051064270.048353.9453oryzias_javanicusENSOJAP0000003002670.616954.3831
ENSG00000081177homo_sapiensENSP0000051064270.370454.9114amphilophus_citrinellusENSACIP0000001554568.495353.4483
ENSG00000081177homo_sapiensENSP0000051064271.497655.8776dicentrarchus_labraxENSDLAP0000502444868.837253.7985
ENSG00000081177homo_sapiensENSP0000051064271.175555.3945amphiprion_perculaENSAPEP0000000944169.496954.0881
ENSG00000081177homo_sapiensENSP0000051064271.014554.5894oryzias_sinensisENSOSIP0000003981370.900354.5016
ENSG00000081177homo_sapiensENSP0000051064279.710167.6329pelodiscus_sinensisENSPSIP0000001122379.710167.6329
ENSG00000081177homo_sapiensENSP0000051064283.413870.2093gopherus_evgoodeiENSGEVP0000502398183.413870.2093
ENSG00000081177homo_sapiensENSP0000051064282.769769.7262chelonoidis_abingdoniiENSCABP0000002307881.45868.6212
ENSG00000081177homo_sapiensENSP0000051064268.921154.4283seriola_dumeriliENSSDUP0000000173768.4854.08
ENSG00000081177homo_sapiensENSP0000051064271.658656.3607cottoperca_gobioENSCGOP0000002555769.749254.8589
ENSG00000081177homo_sapiensENSP0000051064281.964669.4042struthio_camelus_australisENSSCUP0000000442081.964669.4042
ENSG00000081177homo_sapiensENSP0000051064281.642569.0821anser_brachyrhynchusENSABRP0000001780381.774269.1936
ENSG00000081177homo_sapiensENSP0000051064262.479950.0805gasterosteus_aculeatusENSGACP0000000707978.068462.5755
ENSG00000081177homo_sapiensENSP0000051064268.760152.657cynoglossus_semilaevisENSCSEP0000001521358.653844.9176
ENSG00000081177homo_sapiensENSP0000051064272.463854.9114poecilia_formosaENSPFOP0000000479270.422553.3646
ENSG00000081177homo_sapiensENSP0000051064272.624856.8438myripristis_murdjanENSMMDP0000502679369.27854.2243
ENSG00000081177homo_sapiensENSP0000051064271.014555.8776sander_luciopercaENSSLUP0000004593569.122354.3887
ENSG00000081177homo_sapiensENSP0000051064281.481569.0821strigops_habroptilaENSSHBP0000502321081.481569.0821
ENSG00000081177homo_sapiensENSP0000051064271.175555.3945amphiprion_ocellarisENSAOCP0000000459068.740353.4992
ENSG00000081177homo_sapiensENSP0000051064283.252871.0145terrapene_carolina_triunguisENSTMTP0000001222583.252871.0145
ENSG00000081177homo_sapiensENSP0000051064271.336655.3945hucho_huchoENSHHUP0000007833063.46749.2837
ENSG00000081177homo_sapiensENSP0000051064270.853555.2335hucho_huchoENSHHUP0000000859868.111553.096
ENSG00000081177homo_sapiensENSP0000051064271.658656.8438betta_splendensENSBSLP0000005563770.972956.2998
ENSG00000081177homo_sapiensENSP0000051064270.370455.5556pygocentrus_nattereriENSPNAP0000000310869.475454.849
ENSG00000081177homo_sapiensENSP0000051064272.302756.1997anabas_testudineusENSATEP0000002872770.820255.0473
ENSG00000081177homo_sapiensENSP0000051064271.819656.8438seriola_lalandi_dorsalisENSSLDP0000001420869.796655.2426
ENSG00000081177homo_sapiensENSP0000051064270.048354.9114labrus_bergyltaENSLBEP0000003810668.720453.8705
ENSG00000081177homo_sapiensENSP0000051064270.209355.2335pundamilia_nyerereiENSPNYP0000001363068.661454.0157
ENSG00000081177homo_sapiensENSP0000051064271.658656.1997mastacembelus_armatusENSMAMP0000000019369.640154.6166
ENSG00000081177homo_sapiensENSP0000051064271.336655.5556stegastes_partitusENSSPAP0000000327369.218853.9062
ENSG00000081177homo_sapiensENSP0000051064261.996845.7327oncorhynchus_tshawytschaENSOTSP0000508435564.597347.651
ENSG00000081177homo_sapiensENSP0000051064248.792335.9098oncorhynchus_tshawytschaENSOTSP0000500384662.993846.3617
ENSG00000081177homo_sapiensENSP0000051064271.175555.3945acanthochromis_polyacanthusENSAPOP0000000264169.062553.75
ENSG00000081177homo_sapiensENSP0000051064282.125670.2093aquila_chrysaetos_chrysaetosENSACCP0002000630982.125670.2093
ENSG00000081177homo_sapiensENSP0000051064272.785855.3945nothobranchius_furzeriENSNFUP0001501348068.072351.8072
ENSG00000081177homo_sapiensENSP0000051064271.819654.9114cyprinodon_variegatusENSCVAP0000002882766.46850.8197
ENSG00000081177homo_sapiensENSP0000051064269.243252.0129denticeps_clupeoidesENSDCDP0000005279468.25451.2698
ENSG00000081177homo_sapiensENSP0000051064271.980757.0048larimichthys_croceaENSLCRP0000500929667.21853.2331
ENSG00000081177homo_sapiensENSP0000051064271.497656.3607takifugu_rubripesENSTRUP0000000859471.612956.4516
ENSG00000081177homo_sapiensENSP0000051064281.320469.2432ficedula_albicollisENSFALP0000000525381.320469.2432
ENSG00000081177homo_sapiensENSP0000051064269.726253.9453hippocampus_comesENSHCOP0000002725268.404452.9226
ENSG00000081177homo_sapiensENSP0000051064270.370454.5894cyprinus_carpio_carpioENSCCRP0000005044769.365153.8095
ENSG00000081177homo_sapiensENSP0000051064270.209353.9453cyprinus_carpio_carpioENSCCRP0000008355069.7653.6
ENSG00000081177homo_sapiensENSP0000051064280.676368.438coturnix_japonicaENSCJPP0000501841080.676368.438
ENSG00000081177homo_sapiensENSP0000051064272.302754.7504poecilia_latipinnaENSPLAP0000001661270.26653.2081
ENSG00000081177homo_sapiensENSP0000051064267.149852.3349sinocyclocheilus_grahamiENSSGRP0000008492066.7252
ENSG00000081177homo_sapiensENSP0000051064265.378450.5636sinocyclocheilus_grahamiENSSGRP0000008571370.120954.2314
ENSG00000081177homo_sapiensENSP0000051064270.209354.9114maylandia_zebraENSMZEP0000501499668.12553.2812
ENSG00000081177homo_sapiensENSP0000051064264.895351.6908tetraodon_nigroviridisENSTNIP0000000561673.809558.7912
ENSG00000081177homo_sapiensENSP0000051064270.048353.7842paramormyrops_kingsleyaeENSPKIP0000002479369.047653.0159
ENSG00000081177homo_sapiensENSP0000051064273.75256.1997scleropages_formosusENSSFOP0001500994872.12654.9606
ENSG00000081177homo_sapiensENSP0000051064271.980758.6151leptobrachium_leishanenseENSLLEP0000003973673.39959.7701
ENSG00000081177homo_sapiensENSP0000051064266.344651.6908scophthalmus_maximusENSSMAP0000001520963.287349.3088
ENSG00000081177homo_sapiensENSP0000051064271.497655.2335oryzias_melastigmaENSOMEP0000003600870.813454.7049

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0000175enables 3-5-RNA exonuclease activity1IDAHomo_sapiens(9606)Function
GO:0000287enables magnesium ion binding1IDAHomo_sapiens(9606)Function
GO:0000724involved_in double-strand break repair via homologous recombination1IDAHomo_sapiens(9606)Process
GO:0000729involved_in DNA double-strand break processing1IDAHomo_sapiens(9606)Process
GO:0003676enables nucleic acid binding1IEAHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005634is_active_in nucleus1IBAHomo_sapiens(9606)Component
GO:0005737is_active_in cytoplasm1IBAHomo_sapiens(9606)Component
GO:0005739located_in mitochondrion1IDAHomo_sapiens(9606)Component
GO:0005741located_in mitochondrial outer membrane1IDAHomo_sapiens(9606)Component
GO:0005759located_in mitochondrial matrix1IEAHomo_sapiens(9606)Component
GO:0006302involved_in double-strand break repair1IDAHomo_sapiens(9606)Process
GO:0008296enables 3-5-DNA exonuclease activity1IDAHomo_sapiens(9606)Function
GO:0008310enables single-stranded DNA 3-5 DNA exonuclease activity1IDAHomo_sapiens(9606)Function
GO:0008408enables 3-5 exonuclease activity3IBA,IDA,IMPHomo_sapiens(9606)Function
GO:0030145enables manganese ion binding1IDAHomo_sapiens(9606)Function
GO:0031297involved_in replication fork processing1IMPHomo_sapiens(9606)Process
GO:0042803enables protein homodimerization activity1IDAHomo_sapiens(9606)Function
GO:0045111located_in intermediate filament cytoskeleton1IDAHomo_sapiens(9606)Component
GO:0090305involved_in nucleic acid phosphodiester bond hydrolysis1IDAHomo_sapiens(9606)Process
GO:0090734located_in site of DNA damage1IDAHomo_sapiens(9606)Component

Expression