Ensembl ID
ENSG00000081177
Gene ID
55218
Accession
20217
Gene Symbol
EXD2
Alias
EXDL2;C14orf114
Full Name
exonuclease 3'-5' domain containing 2
Position
14 : 69191498 - 69244020
Length
52523 bases
Strand
Plus strand
Status
Confidence
Main interacting RNAs N.A. RBP type
Canonical_RBPs
Summary
Enables 3'-5' exonuclease activity; metal ion binding activity; and protein homodimerization activity. Involved in nucleic acid metabolic process. Located in intermediate filament cytoskeleton; mitochondrial outer membrane; and site of DNA damage. [provided by Alliance of Genome Resources, Apr 2022]
ENSG00000081177 Expression In 33 Tumors
Ensembl ID
Gene symbol
Log2 Foldchange
Pvaue
Cancer
ENSG00000081177
EXD2
-0.4
1.29e-18
KIRC
ENSG00000081177
EXD2
0.55
2.31e-12
KICH
Ensembl ID
Gene symbol
Cancer types
Pubmed ID
ENSG00000081177
EXD2
cancer
26807646
ENSG00000081177
EXD2
cancer
30250899
ENSG00000081177
EXD2
cancer
31255466
Ensembl ID
Gene symbol
Disease/phenotype
Mutation type
Mutated / Total samples
Literature
Ensembl ID
Gene symbol
Cancer
P-value
Which worse
show
ENSG00000081177
EXD2
MESO
0.019
low
show
ENSG00000081177
EXD2
LUSC
0.02
low
show
ENSG00000081177
EXD2
READ
0.013
low
show
ENSG00000081177
EXD2
KIRP
0.013
low
show
ENSG00000081177
EXD2
KICH
0.00035
high
show
ENSG00000081177
EXD2
PCPG
0.00014
high
show
ENSG00000081177
EXD2
BRCA
0.015
high
show
ENSG00000081177
EXD2
UCS
0.02
high
show
ENSG00000081177
EXD2
ESCA
0.0095
low
show
ENSG00000081177
EXD2
TGCT
0.022
low
show
ENSG00000081177
EXD2
BLCA
0.012
high
show
ENSG00000081177
EXD2
CESC
0.018
high
show
ENSG00000081177
EXD2
LIHC
0.00028
high
show
Ensembl ID
Gene symbol
Cancer
CNV type
-log10(q-value)
G-score
average amplitude
frequency
ENSG00000081177
EXD2
CHOL
Del
2.184031
0.330810
0.607863
0.583333
ENSG00000081177
EXD2
LGG
Del
11.079854
0.109953
0.545678
0.233918
ENSG00000081177
EXD2
SARC
Del
1.468639
0.144072
0.575231
0.307393
ENSG00000081177
EXD2
GBM
Del
2.588576
0.072990
0.595861
0.294627
ENSG00000081177
EXD2
LIHC
Del
3.018159
0.098902
0.508979
0.343243
ENSG00000081177
EXD2
BRCA
Del
8.338686
0.108165
0.428891
0.325926
ENSG00000081177
EXD2
KIRC
Del
0.670752
0.023991
0.427303
0.429924
ENSG00000081177
EXD2
OV
Del
5.251195
0.249814
0.542335
0.509499
Copyright © 2023, Bioinformatics Center, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, China. All Rights Reserved.