Ensembl ID ENSG00000081177 Gene ID 55218 Accession 20217
Gene Symbol EXD2 Alias EXDL2;C14orf114 Full Name exonuclease 3'-5' domain containing 2
Position 14 : 69191498 - 69244020 Length 52523 bases Strand Plus strand
Status Confidence Main interacting RNAsN.A.RBP type Canonical_RBPs
Summary Enables 3'-5' exonuclease activity; metal ion binding activity; and protein homodimerization activity. Involved in nucleic acid metabolic process. Located in intermediate filament cytoskeleton; mitochondrial outer membrane; and site of DNA damage. [provided by Alliance of Genome Resources, Apr 2022]

ENSG00000081177 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000081177 EXD2 -0.4 1.29e-18 KIRC
ENSG00000081177 EXD2 0.55 2.31e-12 KICH
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000081177 EXD2 cancer 26807646
ENSG00000081177 EXD2 cancer 30250899
ENSG00000081177 EXD2 cancer 31255466
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000081177 EXD2 MESO 0.019 low
ENSG00000081177 EXD2 LUSC 0.02 low
ENSG00000081177 EXD2 READ 0.013 low
ENSG00000081177 EXD2 KIRP 0.013 low
ENSG00000081177 EXD2 KICH 0.00035 high
ENSG00000081177 EXD2 PCPG 0.00014 high
ENSG00000081177 EXD2 BRCA 0.015 high
ENSG00000081177 EXD2 UCS 0.02 high
ENSG00000081177 EXD2 ESCA 0.0095 low
ENSG00000081177 EXD2 TGCT 0.022 low
ENSG00000081177 EXD2 BLCA 0.012 high
ENSG00000081177 EXD2 CESC 0.018 high
ENSG00000081177 EXD2 LIHC 0.00028 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000081177 EXD2 CHOL Del 2.184031 0.330810 0.607863 0.583333
ENSG00000081177 EXD2 LGG Del 11.079854 0.109953 0.545678 0.233918
ENSG00000081177 EXD2 SARC Del 1.468639 0.144072 0.575231 0.307393
ENSG00000081177 EXD2 GBM Del 2.588576 0.072990 0.595861 0.294627
ENSG00000081177 EXD2 LIHC Del 3.018159 0.098902 0.508979 0.343243
ENSG00000081177 EXD2 BRCA Del 8.338686 0.108165 0.428891 0.325926
ENSG00000081177 EXD2 KIRC Del 0.670752 0.023991 0.427303 0.429924
ENSG00000081177 EXD2 OV Del 5.251195 0.249814 0.542335 0.509499