Functions and Diseases

RBP Type Non-canonical_RBPs
Diseases CancerCHIKVSARS-COV-OC43FlavivirusesHIVRVSARS-COV-2SINVDengueZika
Drug N.A.
Main interacting RNAs N.A.
Moonlighting functions N.A.
Localizations P-body
BulkPerturb-seq DataSet_01_464 DataSet_01_474

Description

Ensembl ID ENSG00000079246 Gene ID 7520 Accession 12833
Symbol XRCC5 Alias KU80;KUB2;Ku86;NFIV;KARP1;KARP-1 Full Name X-ray repair cross complementing 5
Status Confidence Length 98840 bases Strand Plus strand
Position 2 : 216107464 - 216206303 RNA binding domain N.A.
Summary The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq, Jul 2008]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
27852033 The relationship between polymorphisms of XRCC5 genes with astrocytoma prognosis in the Han Chinese population. Xue He 2016-12-20 Oncotarget

Transcripts

Name Transcript ID bp Protein Translation ID
XRCC5-202 ENST00000392133 3761 732aa ENSP00000375978
XRCC5-204 ENST00000429133 576 No protein -
XRCC5-208 ENST00000476360 610 No protein -
XRCC5-201 ENST00000392132 3379 732aa ENSP00000375977
XRCC5-203 ENST00000417391 605 131aa ENSP00000401318
XRCC5-205 ENST00000451695 415 19aa ENSP00000395108
XRCC5-206 ENST00000460284 2962 No protein -
XRCC5-210 ENST00000493706 564 No protein -
XRCC5-207 ENST00000471649 610 No protein -
XRCC5-209 ENST00000485763 616 No protein -

Gene Model

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
27633Coronary Disease6.4010000E-005-

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000079246homo_sapiensENSP0000035319237.766817.2414homo_sapiensENSP0000037597731.420814.3443

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000079246homo_sapiensENSP0000037597799.863499.4536nomascus_leucogenysENSNLEP0000000886299.863499.4536
ENSG00000079246homo_sapiensENSP0000037597799.863499.7268pan_paniscusENSPPAP0000001875499.863499.7268
ENSG00000079246homo_sapiensENSP0000037597799.863499.3169pongo_abeliiENSPPYP0000003198893.12192.6115
ENSG00000079246homo_sapiensENSP0000037597799.863499.7268pan_troglodytesENSPTRP0000002204899.863499.7268
ENSG00000079246homo_sapiensENSP0000037597710099.8634gorilla_gorillaENSGGOP0000001119210099.8634
ENSG00000079246homo_sapiensENSP0000037597785.519170.2186ornithorhynchus_anatinusENSOANP0000003825386.344870.8966
ENSG00000079246homo_sapiensENSP0000037597787.158575.9563sarcophilus_harrisiiENSSHAP0000001727883.947473.1579
ENSG00000079246homo_sapiensENSP0000037597771.857962.4317notamacropus_eugeniiENSMEUP0000000367172.551763.0345
ENSG00000079246homo_sapiensENSP0000037597769.262363.2514choloepus_hoffmanniENSCHOP0000000335974.231367.7892
ENSG00000079246homo_sapiensENSP0000037597791.120282.3771dasypus_novemcinctusENSDNOP0000002845591.120282.3771
ENSG00000079246homo_sapiensENSP0000037597759.699552.7322erinaceus_europaeusENSEEUP0000000482669.9261.76
ENSG00000079246homo_sapiensENSP0000037597777.868969.6721echinops_telfairiENSETEP0000001626877.762669.5771
ENSG00000079246homo_sapiensENSP0000037597798.360796.5847callithrix_jacchusENSCJAP0000002264290.909189.2677
ENSG00000079246homo_sapiensENSP0000037597799.590298.9071cercocebus_atysENSCATP0000003642291.239190.6133
ENSG00000079246homo_sapiensENSP0000037597799.590298.7705macaca_fascicularisENSMFAP0000004391388.902488.1707
ENSG00000079246homo_sapiensENSP0000037597799.726898.9071macaca_mulattaENSMMUP0000000258199.726898.9071
ENSG00000079246homo_sapiensENSP0000037597799.726898.9071macaca_nemestrinaENSMNEP0000000333499.726898.9071
ENSG00000079246homo_sapiensENSP0000037597799.453698.6339papio_anubisENSPANP0000001213584.552883.856
ENSG00000079246homo_sapiensENSP0000037597799.590298.9071mandrillus_leucophaeusENSMLEP0000003417699.590298.9071
ENSG00000079246homo_sapiensENSP0000037597785.109377.5956tursiops_truncatusENSTTRP0000000853584.993277.4898
ENSG00000079246homo_sapiensENSP0000037597783.469974.8634vulpes_vulpesENSVVUP0000001204476.470668.5857
ENSG00000079246homo_sapiensENSP0000037597787.295178.0055mus_spretusMGP_SPRETEiJ_P001921387.295178.0055
ENSG00000079246homo_sapiensENSP0000037597790.983681.8306equus_asinusENSEASP0000501838084.732876.2086
ENSG00000079246homo_sapiensENSP0000037597788.251478.8251capra_hircusENSCHIP0000002519787.771778.3967
ENSG00000079246homo_sapiensENSP0000037597791.120281.694loxodonta_africanaENSLAFP0000000882791.120281.694
ENSG00000079246homo_sapiensENSP0000037597790.983682.9235panthera_leoENSPLOP0000003015290.859582.8104
ENSG00000079246homo_sapiensENSP0000037597791.666783.6066ailuropoda_melanoleucaENSAMEP0000000366391.541683.4925
ENSG00000079246homo_sapiensENSP0000037597789.890781.0109bos_indicus_hybridENSBIXP0000504176780.934872.9397
ENSG00000079246homo_sapiensENSP0000037597792.622984.8361oryctolagus_cuniculusENSOCUP0000000574292.496684.7203
ENSG00000079246homo_sapiensENSP0000037597791.256882.2404equus_caballusENSECAP0000008337182.469174.321
ENSG00000079246homo_sapiensENSP0000037597790.983682.5137canis_lupus_familiarisENSCAFP0084503288884.625276.7471
ENSG00000079246homo_sapiensENSP0000037597791.120283.0601panthera_pardusENSPPRP0000002074490.995982.9468
ENSG00000079246homo_sapiensENSP0000037597786.61278.8251marmota_marmota_marmotaENSMMMP0000002023990.961382.7834
ENSG00000079246homo_sapiensENSP0000037597791.803383.7432balaenoptera_musculusENSBMSP0001000540291.67883.6289
ENSG00000079246homo_sapiensENSP0000037597791.666783.4699cavia_porcellusENSCPOP0000002499790.798482.6793
ENSG00000079246homo_sapiensENSP0000037597788.524680.1913felis_catusENSFCAP0000005320986.74778.581
ENSG00000079246homo_sapiensENSP0000037597762.704956.694ursus_americanusENSUAMP0000000456491.616882.8343
ENSG00000079246homo_sapiensENSP0000037597780.874370.6284monodelphis_domesticaENSMODP0000004704284.450873.7518
ENSG00000079246homo_sapiensENSP0000037597790.300581.0109bison_bison_bisonENSBBBP0000000065590.300581.0109
ENSG00000079246homo_sapiensENSP0000037597791.393483.4699monodon_monocerosENSMMNP0001500926191.268883.3561
ENSG00000079246homo_sapiensENSP0000037597792.213183.3333sus_scrofaENSSSCP0000003150580.838373.0539
ENSG00000079246homo_sapiensENSP0000037597787.021980.4645microcebus_murinusENSMICP0000000815292.587285.6105
ENSG00000079246homo_sapiensENSP0000037597788.661280.7377octodon_degusENSODEP0000001746190.3982.312
ENSG00000079246homo_sapiensENSP0000037597791.120281.694ovis_aries_rambouilletENSOARP0002003292763.888957.2797
ENSG00000079246homo_sapiensENSP0000037597791.666783.8798ursus_maritimusENSUMAP0000002778991.792183.9945
ENSG00000079246homo_sapiensENSP0000037597779.644871.7213ochotona_princepsENSOPRP0000001244079.644871.7213
ENSG00000079246homo_sapiensENSP0000037597789.207680.8743delphinapterus_leucasENSDLEP0000001576788.243280
ENSG00000079246homo_sapiensENSP0000037597791.666783.0601physeter_catodonENSPCTP0000502431491.541682.9468
ENSG00000079246homo_sapiensENSP0000037597787.295177.459mus_caroliMGP_CAROLIEiJ_P001820387.295177.459
ENSG00000079246homo_sapiensENSP0000037597787.568378.2787mus_musculusENSMUSP0000002737987.568378.2787
ENSG00000079246homo_sapiensENSP0000037597785.792475.9563dipodomys_ordiiENSDORP0000001073490.751480.3468
ENSG00000079246homo_sapiensENSP0000037597792.349784.5628mustela_putorius_furoENSMPUP0000001636192.223784.4475
ENSG00000079246homo_sapiensENSP0000037597798.497396.8579aotus_nancymaaeENSANAP0000002123098.497396.8579
ENSG00000079246homo_sapiensENSP0000037597798.633996.9945saimiri_boliviensis_boliviensisENSSBOP0000002572298.633996.9945
ENSG00000079246homo_sapiensENSP0000037597776.912669.2623vicugna_pacosENSVPAP0000000232982.0773.9067
ENSG00000079246homo_sapiensENSP0000037597799.726899.0437chlorocebus_sabaeusENSCSAP0000000534399.726899.0437
ENSG00000079246homo_sapiensENSP0000037597776.502768.1694tupaia_belangeriENSTBEP0000000347476.607468.2627
ENSG00000079246homo_sapiensENSP0000037597787.841578.8251mesocricetus_auratusENSMAUP0000000495187.841578.8251
ENSG00000079246homo_sapiensENSP0000037597791.256883.4699phocoena_sinusENSPSNP0000002161685.64178.3333
ENSG00000079246homo_sapiensENSP0000037597791.530183.1967camelus_dromedariusENSCDRP0000502295591.405283.0832
ENSG00000079246homo_sapiensENSP0000037597790.573882.1038carlito_syrichtaENSTSYP0000001283390.697782.2161
ENSG00000079246homo_sapiensENSP0000037597790.84782.6503panthera_tigris_altaicaENSPTIP0000001839290.723182.5375
ENSG00000079246homo_sapiensENSP0000037597787.021978.2787rattus_norvegicusENSRNOP0000002165687.021978.2787
ENSG00000079246homo_sapiensENSP0000037597792.622985.3825prolemur_simusENSPSMP0000003512992.496685.266
ENSG00000079246homo_sapiensENSP0000037597785.792475.4098microtus_ochrogasterENSMOCP0000002529078.696769.1729
ENSG00000079246homo_sapiensENSP0000037597771.174963.388sorex_araneusENSSARP0000000488671.077863.3015
ENSG00000079246homo_sapiensENSP0000037597787.841580.1913peromyscus_maniculatus_bairdiiENSPEMP0000001146587.961780.301
ENSG00000079246homo_sapiensENSP0000037597790.437281.1475bos_mutusENSBMUP0000002145190.313881.0368
ENSG00000079246homo_sapiensENSP0000037597787.431777.8689mus_spicilegusENSMSIP0000002496762.992156.1024
ENSG00000079246homo_sapiensENSP0000037597788.524679.5082cricetulus_griseus_chok1gshdENSCGRP0000102471388.403879.3997
ENSG00000079246homo_sapiensENSP0000037597780.327973.4973pteropus_vampyrusENSPVAP0000001372380.218373.397
ENSG00000079246homo_sapiensENSP0000037597792.349783.4699myotis_lucifugusENSMLUP0000001244092.349783.4699
ENSG00000079246homo_sapiensENSP0000037597788.114875.6831vombatus_ursinusENSVURP0001000366188.114875.6831
ENSG00000079246homo_sapiensENSP0000037597790.027381.5574rhinolophus_ferrumequinumENSRFEP0001002074189.174680.7848
ENSG00000079246homo_sapiensENSP0000037597792.213184.153neovison_visonENSNVIP0000000679592.087384.0382
ENSG00000079246homo_sapiensENSP0000037597790.437281.4208bos_taurusENSBTAP0000001375890.313881.3097
ENSG00000079246homo_sapiensENSP0000037597792.213184.6995heterocephalus_glaber_femaleENSHGLP0000002233292.213184.6995
ENSG00000079246homo_sapiensENSP0000037597797.950896.7213rhinopithecus_bietiENSRBIP0000001794789.068387.9503
ENSG00000079246homo_sapiensENSP0000037597790.983682.5137canis_lupus_dingoENSCAFP0002003503390.859582.4011
ENSG00000079246homo_sapiensENSP0000037597792.759684.2896sciurus_vulgarisENSSVLP0000501077492.759684.2896
ENSG00000079246homo_sapiensENSP0000037597787.021975.2732phascolarctos_cinereusENSPCIP0000000900487.983476.105
ENSG00000079246homo_sapiensENSP0000037597777.322468.9891procavia_capensisENSPCAP0000000084777.428269.0835
ENSG00000079246homo_sapiensENSP0000037597788.934481.694nannospalax_galiliENSNGAP0000002514989.056181.8057
ENSG00000079246homo_sapiensENSP0000037597790.300580.8743bos_grunniensENSBGRP0000000417581.303872.8167
ENSG00000079246homo_sapiensENSP0000037597792.076584.8361chinchilla_lanigeraENSCLAP0000001725991.204384.0325
ENSG00000079246homo_sapiensENSP0000037597792.076583.1967cervus_hanglu_yarkandensisENSCHYP0000000477891.950983.0832
ENSG00000079246homo_sapiensENSP0000037597791.530183.4699catagonus_wagneriENSCWAP0000000865091.405283.3561
ENSG00000079246homo_sapiensENSP0000037597791.530182.6503ictidomys_tridecemlineatusENSSTOP0000000581191.280782.4251
ENSG00000079246homo_sapiensENSP0000037597790.300582.1038otolemur_garnettiiENSOGAP0000000176589.809881.6576
ENSG00000079246homo_sapiensENSP0000037597798.633997.1311cebus_imitatorENSCCAP0000001860491.974590.5732
ENSG00000079246homo_sapiensENSP0000037597791.530182.6503urocitellus_parryiiENSUPAP0001000658091.405282.5375
ENSG00000079246homo_sapiensENSP0000037597790.437281.9672moschus_moschiferusENSMMSP0000002084991.059282.531
ENSG00000079246homo_sapiensENSP0000037597799.726898.9071rhinopithecus_roxellanaENSRROP0000001574799.726898.9071
ENSG00000079246homo_sapiensENSP0000037597786.885277.7322mus_pahariMGP_PahariEiJ_P007351186.885277.7322
ENSG00000079246homo_sapiensENSP0000037597786.748680.3279propithecus_coquereliENSPCOP0000000969092.162685.3411
ENSG00000079246homo_sapiensENSP0000037597785.792479.3716propithecus_coquereliENSPCOP0000000580492.762285.8198
ENSG00000079246homo_sapiensENSP0000037597737.431720.082caenorhabditis_elegansR07E5.8a.238.429220.6171
ENSG00000079246homo_sapiensENSP0000037597740.437221.8579drosophila_melanogasterFBpp008032242.346222.8898
ENSG00000079246homo_sapiensENSP0000037597748.770530.7377ciona_intestinalisENSCINP0000000933950.566631.8697
ENSG00000079246homo_sapiensENSP0000037597733.879823.9071petromyzon_marinusENSPMAP0000000166468.319648.2094
ENSG00000079246homo_sapiensENSP0000037597764.890744.9454eptatretus_burgeriENSEBUP0000002552668.247147.2701
ENSG00000079246homo_sapiensENSP0000037597771.721354.5082callorhinchus_miliiENSCMIP0000003830768.005251.6839
ENSG00000079246homo_sapiensENSP0000037597764.480950.9563latimeria_chalumnaeENSLACP0000000685977.887861.5512
ENSG00000079246homo_sapiensENSP000003759777555.6011lepisosteus_oculatusENSLOCP0000001188575.515855.9835
ENSG00000079246homo_sapiensENSP0000037597774.726853.9618clupea_harengusENSCHAP0000005829375.344454.4077
ENSG00000079246homo_sapiensENSP0000037597774.590255.8743danio_rerioENSDARP0000013080775.103256.2586
ENSG00000079246homo_sapiensENSP0000037597775.409855.1913carassius_auratusENSCARP0000000995073.796854.0107
ENSG00000079246homo_sapiensENSP0000037597775.683155.8743astyanax_mexicanusENSAMXP0000000338876.413856.4138
ENSG00000079246homo_sapiensENSP0000037597774.316956.0109ictalurus_punctatusENSIPUP0000000961074.931156.4738
ENSG00000079246homo_sapiensENSP0000037597761.202244.9454esox_luciusENSELUP0000006347061.70845.3168
ENSG00000079246homo_sapiensENSP0000037597771.584753.6885electrophorus_electricusENSEEEP0000004416970.810853.1081
ENSG00000079246homo_sapiensENSP0000037597772.54152.8689oncorhynchus_kisutchENSOKIP0000500702570.145351.1229
ENSG00000079246homo_sapiensENSP0000037597772.54153.4153oncorhynchus_mykissENSOMYP0000011681272.343353.2698
ENSG00000079246homo_sapiensENSP0000037597765.84746.9945salmo_salarENSSSAP0000014186473.363852.3592
ENSG00000079246homo_sapiensENSP0000037597772.54152.459salmo_truttaENSSTUP0000002404374.265753.7063
ENSG00000079246homo_sapiensENSP0000037597769.808753.0055gadus_morhuaENSGMOP0000003634466.106150.194
ENSG00000079246homo_sapiensENSP0000037597773.497356.0109fundulus_heteroclitusENSFHEP0000002595373.497356.0109
ENSG00000079246homo_sapiensENSP0000037597769.125751.9126poecilia_reticulataENSPREP0000001448569.220251.9836
ENSG00000079246homo_sapiensENSP0000037597773.907155.0546xiphophorus_maculatusENSXMAP0000001567074.930755.8172
ENSG00000079246homo_sapiensENSP0000037597773.087454.6448oryzias_latipesENSORLP0000002052873.793155.1724
ENSG00000079246homo_sapiensENSP0000037597772.54154.235cyclopterus_lumpusENSCLMP0000504416673.342554.8343
ENSG00000079246homo_sapiensENSP0000037597770.08250.4098oreochromis_niloticusENSONIP0000007367768.766849.4638
ENSG00000079246homo_sapiensENSP0000037597770.628451.0929haplochromis_burtoniENSHBUP0000002257969.959450.6089
ENSG00000079246homo_sapiensENSP0000037597770.628451.0929astatotilapia_callipteraENSACLP0000002401969.959450.6089
ENSG00000079246homo_sapiensENSP0000037597773.087453.1421sparus_aurataENSSAUP0001006930372.297352.5676
ENSG00000079246homo_sapiensENSP0000037597765.163948.224lates_calcariferENSLCAP0001005101671.621653.003
ENSG00000079246homo_sapiensENSP0000037597778.005562.7049xenopus_tropicalisENSXETP0000006443074.445959.8435
ENSG00000079246homo_sapiensENSP0000037597785.109370.082chrysemys_picta_belliiENSCPBP0000001873884.417369.5122
ENSG00000079246homo_sapiensENSP0000037597773.907160.7924sphenodon_punctatusENSSPUP0000001990580.267166.0237
ENSG00000079246homo_sapiensENSP0000037597782.240468.306crocodylus_porosusENSCPRP0000500029582.352968.3995
ENSG00000079246homo_sapiensENSP0000037597753.825144.6721laticauda_laticaudataENSLLTP0000000537078.642765.2695
ENSG00000079246homo_sapiensENSP0000037597775.956363.388notechis_scutatusENSNSUP0000001618674.831862.4495
ENSG00000079246homo_sapiensENSP0000037597775.136662.2951pseudonaja_textilisENSPTXP0000000970879.941966.2791
ENSG00000079246homo_sapiensENSP0000037597779.91865.847anas_platyrhynchos_platyrhynchosENSAPLP0000001261180.689766.4828
ENSG00000079246homo_sapiensENSP0000037597780.191366.2568gallus_gallusENSGALP0001003066676.432363.151
ENSG00000079246homo_sapiensENSP0000037597780.191365.4372meleagris_gallopavoENSMGAP0000001223880.521365.7064
ENSG00000079246homo_sapiensENSP0000037597779.644864.071serinus_canariaENSSCAP0000001719380.192664.5117
ENSG00000079246homo_sapiensENSP0000037597779.781465.1639parus_majorENSPMJP0000002711980.330165.6121
ENSG00000079246homo_sapiensENSP0000037597780.874366.8033anolis_carolinensisENSACAP0000002399176.584763.26
ENSG00000079246homo_sapiensENSP0000037597766.939947.9508neolamprologus_brichardiENSNBRP0000002158767.773248.5477
ENSG00000079246homo_sapiensENSP0000037597772.267860.1093naja_najaENSNNAP0000002179879.909466.4653
ENSG00000079246homo_sapiensENSP0000037597782.240468.7158podarcis_muralisENSPMRP0000003043882.352968.8099
ENSG00000079246homo_sapiensENSP0000037597778.142162.5683geospiza_fortisENSGFOP0000000042780.67764.598
ENSG00000079246homo_sapiensENSP0000037597780.327964.3443taeniopygia_guttataENSTGUP0000000521180.991764.876
ENSG00000079246homo_sapiensENSP0000037597774.726856.9672erpetoichthys_calabaricusENSECRP0000001118876.077957.9972
ENSG00000079246homo_sapiensENSP0000037597773.907155.4645kryptolebias_marmoratusENSKMAP0000001594774.620756
ENSG00000079246homo_sapiensENSP0000037597781.284266.5301salvator_merianaeENSSMRP0000001504181.955967.0799
ENSG00000079246homo_sapiensENSP0000037597765.983649.1803oryzias_javanicusENSOJAP0000004778368.901651.3552
ENSG00000079246homo_sapiensENSP0000037597768.715850amphilophus_citrinellusENSACIP0000000225968.622149.9318
ENSG00000079246homo_sapiensENSP0000037597774.453655.8743amphiprion_perculaENSAPEP0000002213275.380456.5698
ENSG00000079246homo_sapiensENSP0000037597773.22454.5082oryzias_sinensisENSOSIP0000003485973.024554.3597
ENSG00000079246homo_sapiensENSP0000037597784.562870.4918pelodiscus_sinensisENSPSIP0000001573383.423269.5418
ENSG00000079246homo_sapiensENSP0000037597785.245970.9016gopherus_evgoodeiENSGEVP0000502413985.362570.9986
ENSG00000079246homo_sapiensENSP0000037597780.191366.1202chelonoidis_abingdoniiENSCABP0000001167680.631966.4835
ENSG00000079246homo_sapiensENSP0000037597773.907154.918seriola_dumeriliENSSDUP0000002390874.517955.3719
ENSG00000079246homo_sapiensENSP0000037597773.087454.7814cottoperca_gobioENSCGOP0000002902574.099755.5402
ENSG00000079246homo_sapiensENSP0000037597780.737765.1639struthio_camelus_australisENSSCUP0000000653278.905263.6849
ENSG00000079246homo_sapiensENSP0000037597780.874366.5301anser_brachyrhynchusENSABRP0000001419781.207166.8038
ENSG00000079246homo_sapiensENSP0000037597772.54154.5082gasterosteus_aculeatusENSGACP0000000814972.54154.5082
ENSG00000079246homo_sapiensENSP0000037597772.404453.8251cynoglossus_semilaevisENSCSEP0000001669172.010953.5326
ENSG00000079246homo_sapiensENSP0000037597774.043755.7377poecilia_formosaENSPFOP0000000025575.069356.5097
ENSG00000079246homo_sapiensENSP0000037597773.22453.5519myripristis_murdjanENSMMDP0000502413473.324253.6252
ENSG00000079246homo_sapiensENSP0000037597769.672152.7322sander_luciopercaENSSLUP0000005422773.699455.7803
ENSG00000079246homo_sapiensENSP0000037597774.180359.5628strigops_habroptilaENSSHBP0000502382578.129562.7338
ENSG00000079246homo_sapiensENSP0000037597773.22455.0546amphiprion_ocellarisENSAOCP0000000996575.280956.6011
ENSG00000079246homo_sapiensENSP0000037597784.426269.8087terrapene_carolina_triunguisENSTMTP0000000047584.541769.9042
ENSG00000079246homo_sapiensENSP0000037597723.770517.7596hucho_huchoENSHHUP0000001064557.236842.7632
ENSG00000079246homo_sapiensENSP0000037597772.814253.8251betta_splendensENSBSLP0000001539873.618854.4199
ENSG00000079246homo_sapiensENSP0000037597773.360753.8251pygocentrus_nattereriENSPNAP0000002884672.96253.5326
ENSG00000079246homo_sapiensENSP0000037597773.22454.7814anabas_testudineusENSATEP0000005078072.530454.2625
ENSG00000079246homo_sapiensENSP0000037597712.97818.87978ciona_savignyiENSCSAVP0000000028359.37540.625
ENSG00000079246homo_sapiensENSP0000037597733.196716.1202saccharomyces_cerevisiaeYMR106C38.632818.7599
ENSG00000079246homo_sapiensENSP0000037597772.950853.6885seriola_lalandi_dorsalisENSSLDP0000000925574.685354.965
ENSG00000079246homo_sapiensENSP0000037597773.907155.0546labrus_bergyltaENSLBEP0000000432174.723855.663
ENSG00000079246homo_sapiensENSP0000037597773.770554.235pundamilia_nyerereiENSPNYP0000000109774.688854.9101
ENSG00000079246homo_sapiensENSP0000037597765.84748.4973mastacembelus_armatusENSMAMP0000006828152.334438.5451
ENSG00000079246homo_sapiensENSP0000037597774.316955.0546stegastes_partitusENSSPAP0000000505970.741252.4057
ENSG00000079246homo_sapiensENSP0000037597765.84748.0874oncorhynchus_tshawytschaENSOTSP0000500774369.956551.0885
ENSG00000079246homo_sapiensENSP0000037597774.316955.6011acanthochromis_polyacanthusENSAPOP0000001687175.034556.1379
ENSG00000079246homo_sapiensENSP0000037597780.054665.7104aquila_chrysaetos_chrysaetosENSACCP0002000364380.27465.8904
ENSG00000079246homo_sapiensENSP0000037597773.22453.5519nothobranchius_furzeriENSNFUP0001505384573.93154.069
ENSG00000079246homo_sapiensENSP0000037597773.907155.3279cyprinodon_variegatusENSCVAP0000001603574.008255.4036
ENSG00000079246homo_sapiensENSP0000037597773.497354.0984denticeps_clupeoidesENSDCDP0000001806274.002854.4704
ENSG00000079246homo_sapiensENSP0000037597775.273254.3716larimichthys_croceaENSLCRP0000502360175.790954.7455
ENSG00000079246homo_sapiensENSP0000037597773.770553.9618takifugu_rubripesENSTRUP0000002851274.482854.4828
ENSG00000079246homo_sapiensENSP0000037597778.825164.2076ficedula_albicollisENSFALP0000000413979.367364.6492
ENSG00000079246homo_sapiensENSP0000037597771.311552.0492hippocampus_comesENSHCOP0000002664571.604952.2634
ENSG00000079246homo_sapiensENSP0000037597742.62331.1475cyprinus_carpio_carpioENSCCRP0000009576560.231744.0154
ENSG00000079246homo_sapiensENSP0000037597773.633954.5082cyprinus_carpio_carpioENSCCRP0000000442772.058853.3422
ENSG00000079246homo_sapiensENSP0000037597779.508265.3005coturnix_japonicaENSCJPP0000501582879.835465.5693
ENSG00000079246homo_sapiensENSP0000037597774.043755.6011poecilia_latipinnaENSPLAP0000003046375.069356.3712
ENSG00000079246homo_sapiensENSP0000037597770.218651.2295sinocyclocheilus_grahamiENSSGRP0000007612270.994551.7956
ENSG00000079246homo_sapiensENSP0000037597773.907154.3716maylandia_zebraENSMZEP0000501001774.827155.0484
ENSG00000079246homo_sapiensENSP0000037597768.032849.7268maylandia_zebraENSMZEP0000501218772.069552.6773
ENSG00000079246homo_sapiensENSP0000037597771.584752.8689tetraodon_nigroviridisENSTNIP0000001956371.97853.1593
ENSG00000079246homo_sapiensENSP0000037597771.311551.9126paramormyrops_kingsleyaeENSPKIP0000002248771.801952.2696
ENSG00000079246homo_sapiensENSP0000037597771.448152.3224scleropages_formosusENSSFOP0001504807370.107251.3405
ENSG00000079246homo_sapiensENSP0000037597776.639357.9235leptobrachium_leishanenseENSLLEP0000003976672.200854.5689
ENSG00000079246homo_sapiensENSP0000037597767.896250scophthalmus_maximusENSSMAP0000005280449.50236.4542
ENSG00000079246homo_sapiensENSP0000037597772.950854.5082oryzias_melastigmaENSOMEP0000002231573.655255.0345

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0000723involved_in telomere maintenance1IBAHomo_sapiens(9606)Process
GO:0000725involved_in recombinational repair1NASHomo_sapiens(9606)Process
GO:0000781located_in chromosome, telomeric region2HDA,IDAHomo_sapiens(9606)Component
GO:0000783part_of nuclear telomere cap complex1TASHomo_sapiens(9606)Component
GO:0000976enables transcription cis-regulatory region binding1IDAHomo_sapiens(9606)Function
GO:0002218involved_in activation of innate immune response1IDAHomo_sapiens(9606)Process
GO:0003677enables DNA binding1NASHomo_sapiens(9606)Function
GO:0003678enables DNA helicase activity1IEAHomo_sapiens(9606)Function
GO:0003684enables damaged DNA binding1IEAHomo_sapiens(9606)Function
GO:0003690contributes_to double-stranded DNA binding1IBAHomo_sapiens(9606)Function
GO:0003691contributes_to double-stranded telomeric DNA binding1IDAHomo_sapiens(9606)Function
GO:0003723enables RNA binding2HDA,IDAHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005524enables ATP binding1IEAHomo_sapiens(9606)Function
GO:0005576located_in extracellular region1TASHomo_sapiens(9606)Component
GO:0005634located_in nucleus1IDAHomo_sapiens(9606)Component
GO:0005654located_in nucleoplasm2IDA,TASHomo_sapiens(9606)Component
GO:0005730located_in nucleolus1IDAHomo_sapiens(9606)Component
GO:0005829located_in cytosol1TASHomo_sapiens(9606)Component
GO:0005886located_in plasma membrane1IDAHomo_sapiens(9606)Component
GO:0006302involved_in double-strand break repair1IMPHomo_sapiens(9606)Process
GO:0006303involved_in double-strand break repair via nonhomologous end joining5IBA,IDA,IMP,NAS,TASHomo_sapiens(9606)Process
GO:0006310involved_in DNA recombination1TASHomo_sapiens(9606)Process
GO:0006974involved_in DNA damage response1IMPHomo_sapiens(9606)Process
GO:0008047enables enzyme activator activity1TASHomo_sapiens(9606)Function
GO:0008094enables ATP-dependent activity, acting on DNA1IDAHomo_sapiens(9606)Function
GO:0009410involved_in response to xenobiotic stimulus1IEAHomo_sapiens(9606)Process
GO:0016020located_in membrane1HDAHomo_sapiens(9606)Component
GO:0016887enables ATP hydrolysis activity1IDAHomo_sapiens(9606)Function
GO:0022008involved_in neurogenesis1IEAHomo_sapiens(9606)Process
GO:0031625enables ubiquitin protein ligase binding1IPIHomo_sapiens(9606)Function
GO:0032040part_of small-subunit processome1IDAHomo_sapiens(9606)Component
GO:0032204involved_in regulation of telomere maintenance1TASHomo_sapiens(9606)Process
GO:0032212involved_in positive regulation of telomere maintenance via telomerase1IMPHomo_sapiens(9606)Process
GO:0032508involved_in DNA duplex unwinding1IEAHomo_sapiens(9606)Process
GO:0032991part_of protein-containing complex1IDAHomo_sapiens(9606)Component
GO:0032993part_of protein-DNA complex1IDAHomo_sapiens(9606)Component
GO:0034462involved_in small-subunit processome assembly1IDAHomo_sapiens(9606)Process
GO:0034511enables U3 snoRNA binding1IDAHomo_sapiens(9606)Function
GO:0034774located_in secretory granule lumen1TASHomo_sapiens(9606)Component
GO:0042162enables telomeric DNA binding3IBA,IDA,TASHomo_sapiens(9606)Function
GO:0043085involved_in positive regulation of catalytic activity1TASHomo_sapiens(9606)Process
GO:0043564part_of Ku70:Ku80 complex4IBA,IDA,IPI,TASHomo_sapiens(9606)Component
GO:0044877enables protein-containing complex binding1IPIHomo_sapiens(9606)Function
GO:0045027contributes_to DNA end binding2IDAHomo_sapiens(9606)Function
GO:0045087involved_in innate immune response1IEAHomo_sapiens(9606)Process
GO:0045860involved_in positive regulation of protein kinase activity1IDAHomo_sapiens(9606)Process
GO:0045892involved_in negative regulation of DNA-templated transcription1IMPHomo_sapiens(9606)Process
GO:0048660involved_in regulation of smooth muscle cell proliferation1IMPHomo_sapiens(9606)Process
GO:0050769involved_in positive regulation of neurogenesis1IEAHomo_sapiens(9606)Process
GO:0051575contributes_to 5-deoxyribose-5-phosphate lyase activity1IMPHomo_sapiens(9606)Function
GO:0051973involved_in positive regulation of telomerase activity1TASHomo_sapiens(9606)Process
GO:0060218involved_in hematopoietic stem cell differentiation1IEAHomo_sapiens(9606)Process
GO:0070198involved_in protein localization to chromosome, telomeric region1TASHomo_sapiens(9606)Process
GO:0070418part_of DNA-dependent protein kinase complex1IPIHomo_sapiens(9606)Component
GO:0070419part_of nonhomologous end joining complex1IDAHomo_sapiens(9606)Component
GO:0071398involved_in cellular response to fatty acid1IEAHomo_sapiens(9606)Process
GO:0071425involved_in hematopoietic stem cell proliferation1IEAHomo_sapiens(9606)Process
GO:0071475involved_in cellular hyperosmotic salinity response1IEAHomo_sapiens(9606)Process
GO:0071480involved_in cellular response to gamma radiation1IDAHomo_sapiens(9606)Process
GO:0071481involved_in cellular response to X-ray1IEAHomo_sapiens(9606)Process
GO:0090734located_in site of DNA damage1IMPHomo_sapiens(9606)Component
GO:1904430involved_in negative regulation of t-circle formation1IMPHomo_sapiens(9606)Process
GO:1990830involved_in cellular response to leukemia inhibitory factor1IEAHomo_sapiens(9606)Process
GO:1990904part_of ribonucleoprotein complex1IDAHomo_sapiens(9606)Component

Expression