Functions and Diseases

RBP Type Canonical_RBPs
Diseases Cancer
Drug N.A.
Main interacting RNAs mRNA
Moonlighting functions N.A.
Localizations Stress granucleFibrillar center
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000078328 Gene ID 54715 Accession 18222
Symbol RBFOX1 Alias 2BP1;FOX1;A2BP1;FOX-1;HRNBP1 Full Name RNA binding fox-1 homolog 1
Status Confidence Length 2473539 bases Strand Plus strand
Position 16 : 5239802 - 7713340 RNA binding domain Fox-1_C , RRM_1
Summary The Fox-1 family of RNA-binding proteins is evolutionarily conserved, and regulates tissue-specific alternative splicing in metazoa. Fox-1 recognizes a (U)GCAUG stretch in regulated exons or in flanking introns. The protein binds to the C-terminus of ataxin-2 and may contribute to the restricted pathology of spinocerebellar ataxia type 2 (SCA2). Ataxin-2 is the product of the SCA2 gene which causes familial neurodegenerative diseases. Fox-1 and ataxin-2 are both localized in the trans-Golgi network. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000450402 RRM_1 PF00076 1.1e-17 1
ENSP00000447281 RRM_1 PF00076 1.1e-17 1
ENSP00000507921 RRM_1 PF00076 1.4e-17 1
ENSP00000507921 Fox-1_C PF12414 2.4e-42 2
ENSP00000502217 RRM_1 PF00076 1.5e-17 1
ENSP00000502217 Fox-1_C PF12414 2.7e-42 2
ENSP00000502682 RRM_1 PF00076 1.5e-17 1
ENSP00000502682 Fox-1_C PF12414 2.7e-42 2
ENSP00000347855 RRM_1 PF00076 1.5e-17 1
ENSP00000347855 Fox-1_C PF12414 1.1e-39 2
ENSP00000502646 RRM_1 PF00076 1.5e-17 1
ENSP00000502646 Fox-1_C PF12414 4.5e-43 2
ENSP00000402745 RRM_1 PF00076 1.5e-17 1
ENSP00000402745 Fox-1_C PF12414 1.8e-40 2
ENSP00000447753 RRM_1 PF00076 1.6e-17 1
ENSP00000447753 Fox-1_C PF12414 4.4e-43 2
ENSP00000502616 RRM_1 PF00076 1.6e-17 1
ENSP00000502616 Fox-1_C PF12414 3e-42 2
ENSP00000507562 RRM_1 PF00076 1.6e-17 1
ENSP00000507562 Fox-1_C PF12414 3e-42 2
ENSP00000484837 RRM_1 PF00076 1.7e-17 1
ENSP00000484837 Fox-1_C PF12414 4.5e-43 2
ENSP00000458748 RRM_1 PF00076 1.7e-17 1
ENSP00000458748 Fox-1_C PF12414 5e-43 2
ENSP00000516112 RRM_1 PF00076 1.7e-17 1
ENSP00000516112 Fox-1_C PF12414 5.1e-43 2
ENSP00000309117 RRM_1 PF00076 1.7e-17 1
ENSP00000309117 Fox-1_C PF12414 2e-40 2
ENSP00000447717 RRM_1 PF00076 1.8e-17 1
ENSP00000447717 Fox-1_C PF12414 5.6e-43 2
ENSP00000450031 RRM_1 PF00076 1.8e-17 1
ENSP00000450031 Fox-1_C PF12414 5.6e-43 2
ENSP00000501599 RRM_1 PF00076 1.8e-17 1
ENSP00000501599 Fox-1_C PF12414 5.6e-43 2
ENSP00000502718 RRM_1 PF00076 1.8e-17 1
ENSP00000502718 Fox-1_C PF12414 5.6e-43 2
ENSP00000391269 RRM_1 PF00076 1.9e-17 1
ENSP00000391269 Fox-1_C PF12414 6.3e-43 2
ENSP00000501878 RRM_1 PF00076 2e-17 1
ENSP00000501878 Fox-1_C PF12414 3.6e-42 2
ENSP00000446842 RRM_1 PF00076 2.2e-17 1
ENSP00000446842 Fox-1_C PF12414 4.4e-42 2
ENSP00000493041 RRM_1 PF00076 3.1e-17 1
ENSP00000493041 Fox-1_C PF12414 6.2e-42 2
ENSP00000448496 RRM_1 PF00076 2.2e-07 1
ENSP00000448496 Fox-1_C PF12414 3.2e-42 2
ENSP00000438768 Fox-1_C PF12414 3.1e-42 1
ENSP00000454250 Fox-1_C PF12414 9.7e-13 1

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
27146458 RBFOX1 and RBFOX2 are dispensable in iPSCs and iPSC-derived neurons and do not contribute to neural-specific paternal UBE3A silencing. Pin-Fang Chen 2016-05-05 Scientific reports
29621484 Rbfox1 Regulates Synaptic Transmission through the Inhibitory Neuron-Specific vSNARE Vamp1. K Celine Vuong 2018-04-04 Neuron
24613350 HITS-CLIP and integrative modeling define the Rbfox splicing-regulatory network linked to brain development and autism. M Sebastien Weyn-Vanhentenryck 2014-03-27 Cell reports
30185603 Synaptic dysfunction in neurodegenerative and neurodevelopmental diseases: an overview of induced pluripotent stem-cell-based disease models. Era Taoufik 2018-09-01 Open biology
31963575 Regulation of BDNF-TrkB Signaling and Potential Therapeutic Strategies for Parkinson's Disease. Wook Jin 2020-01-17 Journal of clinical medicine
31128889 Germline Variants Impact Somatic Events during Tumorigenesis. R Johnny Ramroop 2019-07-01 Trends in genetics : TIG
30083133 Perspective: A Neuro-Hormonal Systems Approach to Understanding the Complexity of Cryptorchidism Susceptibility. S Julia Barthold 2018-01-01 Frontiers in endocrinology
26222184 Focus on 16p13.3 Locus in Colon Cancer. Evi Mampaey 2015-01-01 PloS one
32568366 Association Between Common Variants in RBFOX1, an RNA-Binding Protein, and Brain Amyloidosis in Early and Preclinical Alzheimer Disease. S Neha Raghavan 2020-10-01 JAMA neurology
23829686 Rank-based genome-wide analysis reveals the association of ryanodine receptor-2 gene variants with childhood asthma among human populations. Lili Ding 2013-07-05 Human genomics
29765130 Copy number variants implicate cardiac function and development pathways in earthquake-induced stress cardiomyopathy. J Cameron Lacey 2018-05-15 Scientific reports
35767654 MECP2-related pathways are dysregulated in a cortical organoid model of myotonic dystrophy. H Kathryn Morelli 2022-06-29 Science translational medicine
33131714 Pleiotropy and Cross-Disorder Genetics Among Psychiatric Disorders. H Phil Lee 2021-01-01 Biological psychiatry
34425903 Developmental dynamics of voltage-gated sodium channel isoform expression in the human and mouse brain. Lindsay Liang 2021-08-23 Genome medicine
29358748 Stress-dependent miR-980 regulation of Rbfox1/A2bp1 promotes ribonucleoprotein granule formation and cell survival. M Mariya Kucherenko 2018-01-22 Nature communications
34326310 Identification of pleiotropy at the gene level between psychiatric disorders and related traits. Tatiana Polushina 2021-07-29 Translational psychiatry
36833427 Copy Number Variations in Children with Tourette Syndrome: Systematic Investigation in a Clinical Setting. Federica Saia 2023-02-15 Genes
35865099 Non-small molecule PROTACs (NSM-PROTACs): Protein degradation kaleidoscope. Sinan Ma 2022-07-01 Acta pharmaceutica Sinica. B
27637763 Copy-number variant analysis of classic heterotaxy highlights the importance of body patterning pathways. M Erin Hagen 2016-12-01 Human genetics
28817824 Parametric Linkage Analysis Identifies Five Novel Genome-Wide Significant Loci for Familial Lung Cancer. M Anthony Musolf 2016-01-01 Human heredity

Transcripts

Name Transcript ID bp Protein Translation ID
RBFOX1-218 ENST00000569895 829 No protein -
RBFOX1-223 ENST00000641259 3651 582aa ENSP00000493041
RBFOX1-221 ENST00000585867 1580 201aa ENSP00000493140
RBFOX1-211 ENST00000550418 4884 397aa ENSP00000450031
RBFOX1-209 ENST00000547605 1811 262aa ENSP00000450402
RBFOX1-214 ENST00000553186 2196 370aa ENSP00000447753
RBFOX1-207 ENST00000547372 3524 466aa ENSP00000446842
RBFOX1-210 ENST00000548749 538 No protein -
RBFOX1-203 ENST00000422070 1684 425aa ENSP00000391269
RBFOX1-234 ENST00000675842 4254 397aa ENSP00000501599
RBFOX1-228 ENST00000675140 2960 No protein -
RBFOX1-205 ENST00000535565 1599 380aa ENSP00000438768
RBFOX1-208 ENST00000547427 557 No protein -
RBFOX1-213 ENST00000552089 1430 391aa ENSP00000448496
RBFOX1-230 ENST00000675459 4126 374aa ENSP00000502616
RBFOX1-212 ENST00000551752 974 263aa ENSP00000447281
RBFOX1-232 ENST00000675653 4019 397aa ENSP00000502718
RBFOX1-206 ENST00000547338 1513 397aa ENSP00000447717
RBFOX1-224 ENST00000674626 4501 354aa ENSP00000502217
RBFOX1-231 ENST00000675562 3898 415aa ENSP00000501878
RBFOX1-240 ENST00000705321 1507 377aa ENSP00000516112
RBFOX1-204 ENST00000436368 1530 392aa ENSP00000402745
RBFOX1-201 ENST00000311745 3268 418aa ENSP00000309117
RBFOX1-222 ENST00000620507 4018 375aa ENSP00000484837
RBFOX1-202 ENST00000355637 4062 395aa ENSP00000347855
RBFOX1-217 ENST00000569889 503 No protein -
RBFOX1-237 ENST00000676253 4496 No protein -
RBFOX1-235 ENST00000675904 4547 No protein -
RBFOX1-236 ENST00000676218 3835 351aa ENSP00000502646
RBFOX1-225 ENST00000674792 4002 354aa ENSP00000502682
RBFOX1-238 ENST00000682918 3851 349aa ENSP00000507921
RBFOX1-239 ENST00000683326 3962 376aa ENSP00000507562
RBFOX1-220 ENST00000570626 3709 372aa ENSP00000458748
RBFOX1-233 ENST00000675725 4796 No protein -
RBFOX1-226 ENST00000674859 4378 No protein -
RBFOX1-227 ENST00000675077 4320 No protein -
RBFOX1-229 ENST00000675242 4323 No protein -
RBFOX1-215 ENST00000564850 293 No protein -
RBFOX1-216 ENST00000567470 420 74aa ENSP00000454250
RBFOX1-219 ENST00000570188 568 No protein -

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
528Respiratory Function Tests9.60497545732297E-717903307
662Respiratory Function Tests6.07071609624591E-717903307
916Body Mass Index4.9707081993607E-517903300
1202Body Mass Index2.41071819904284E-517903300
1382Body Weight2.37881990298074E-517903300
1478Body Weight8.56552110343686E-517903300
3537Cholesterol, HDL4.6411424362347E-517903299
4427Cholesterol, LDL1.61796762560761E-717903299
5131Cholesterol, HDL7.81511931955414E-517903299
5167Cholesterol, HDL4.70131377372507E-517903299
5280Cholesterol, LDL6.63524216522049E-517903299
5288Cholesterol, LDL5.55400436901277E-517903299
5598Lipoproteins, VLDL1.939235320682E-617903299
5658Apolipoproteins B7.24523788024701E-617903299
6293Erythrocytes1.94598408342905E-517903294
6307Erythrocytes7.6855409045784E-517903294
7394Calcium-Binding Proteins3.0812454326985E-917903293
7396Calcium-Binding Proteins4.28359325123193E-1017903293
7766Uric Acid8.11426262097292E-517903292
8074Neoplasms6.86545187570505E-617903305
8464Atrial Fibrillation2.17461237843389E-717903304
8479Atrial Fibrillation1.97686276381724E-717903304
9237Echocardiography7.55799577747581E-517903301
12135Inflammatory Bowel Diseases6.312E-517068223
12351Amyotrophic Lateral Sclerosis4.6690000E-00518057069
12807Bipolar Disorder3.7E-519488044
12820Bipolar Disorder7.46E-519488044
12843Bipolar Disorder9.1E-519488044
13994Myocardial Infarction3.3445516E-004-
14702Alzheimer Disease2.5425511E-00517998437
18834Platelet Count4.963e-005-
20083Creatinine1.887e-005-
20432Alanine Transaminase8.681e-005-
20456Alanine Transaminase8.914e-005-
20756Bilirubin1.512e-005-
21793Neuroticism6.777e-005-
22005Personality4.974e-005-
22070Personality8.796e-005-
22075Personality4.637e-005-
22078Personality6.38e-005-
22079Personality6.38e-005-
23152Body Height8.6580000E-005-
23647Body Height3.4030000E-005-
24706Muscle, Skeletal2.3350000E-005-
25794Arteries6.7710000E-005-
26198Arteries6.9920000E-005-
27670Coronary Disease7.9020000E-005-
28509Social Support3.0230000E-005-
28511Social Support2.3210000E-005-
28512Social Support7.5830000E-005-
28523Social Support3.0960000E-005-
28526Social Support5.0680000E-005-
28688Creatinine4.3060000E-005-
30507Eosinophils5.0010000E-005-
30583Monocytes5.7900000E-007-
30736Leukocyte Count6.6610000E-005-
30754Leukocyte Count4.2590000E-005-
31204Erythrocyte Indices3.0240000E-005-
31205Erythrocyte Indices9.8060000E-005-
31235Erythrocyte Indices3.6990000E-005-
32291Atherosclerosis7.8036079E-005-
32466Blood Pressure9.8156298E-005-
33370Urine5.2268531E-005-
34145Leukoaraiosis6.9724727E-005-
35051Platelet Function Tests3.0262500E-005-
35069Platelet Function Tests1.2489500E-005-
35070Platelet Function Tests2.3613900E-005-
35082Platelet Function Tests1.3637700E-005-
35107Platelet Function Tests6.1100000E-006-
35190Platelet Function Tests3.5400000E-006-
37302Platelet Function Tests9.6300000E-006-
38500Platelet Function Tests6.6600000E-016-
38578Platelet Function Tests8.8800000E-016-
38804Platelet Function Tests8.9000000E-006-
38806Platelet Function Tests2.1800000E-006-
39628Platelet Function Tests2.4619300E-005-
39637Platelet Function Tests3.4951200E-005-
39699Platelet Function Tests1.3600300E-005-
39735Platelet Function Tests1.6744900E-005-
42200Platelet Function Tests6.2814005E-006-
42343Platelet Function Tests6.2814005E-006-
42967Platelet Function Tests3.8075631E-006-
43031Platelet Function Tests7.3853593E-006-
43231Platelet Function Tests9.1581571E-006-
44146Platelet Function Tests2.0925600E-005-
44432Platelet Function Tests2.2204460E-016-
44508Platelet Function Tests2.2204460E-016-
45113Platelet Function Tests1.7962800E-005-
45615Platelet Function Tests7.9853873E-006-
46172Platelet Function Tests9.5653149E-006-
46190Platelet Function Tests9.5933578E-006-
46218Platelet Function Tests4.7666122E-006-
46223Platelet Function Tests2.2019332E-006-
46227Platelet Function Tests4.4178138E-006-
46821Platelet Function Tests6.2314000E-005-
49076Child Development Disorders, Pervasive1.8036500E-005-
52060Child Development Disorders, Pervasive2.8000000E-005-
52093Child Development Disorders, Pervasive4.1000000E-005-
52118Child Development Disorders, Pervasive5.3000000E-005-
52135Child Development Disorders, Pervasive5.8000000E-005-
52258Child Development Disorders, Pervasive6.1000000E-005-
52281Child Development Disorders, Pervasive2.5000000E-005-
52287Child Development Disorders, Pervasive2.6000000E-005-
52297Child Development Disorders, Pervasive2.0000000E-005-
52319Child Development Disorders, Pervasive2.0000000E-005-
52323Child Development Disorders, Pervasive5.7000000E-005-
53305Triiodothyronine8.3260000E-006-
53323Triiodothyronine8.0020000E-006-
53353Insulin-Like Growth Factor Binding Protein 15.0660000E-005-
54768Fibrinogen4.7970000E-005-
54910gamma-Glutamyltransferase2.8960000E-005-
54915gamma-Glutamyltransferase2.2050000E-006-
55307monocyte chemoattractant protein 1 (66-77)9.9100000E-006-
55771beta Carotene2.6210000E-005-
57771Plaque, Atherosclerotic2.8450000E-00521909108
61563Cognition Disorders5E-926252872
61564Cognitive Dysfunction5E-926252872
61797Diabetic Retinopathy6E-721441570
62143Autosomal dominant compelling helio ophthalmic outburst syndrome3E-2127182965
62912Body Weight2E-623251661
65540Refraction, Ocular4E-923474815
65613Myopia2E-625233373
71654Rhinitis, Allergic5E-725085501
72271Conduct Disorder3E-618846501
75057Gout1E-722179738
75186Mental Disorders5E-620889312
75913Refraction, Ocular6E-1023396134
75963Heart Rate2E-723583979
76122Intraocular Pressure4E-624002674
76680Extraversion (Psychology)2E-627918536
77145Attention Deficit Disorder with Hyperactivity9E-618951430
77146Conduct Disorder9E-618951430
78256Body Mass Index3E-625673413
79274Emotions2E-727089181
79679Paliperidone Palmitate3E-727846195
79680Schizophrenia3E-727846195
80526Periodontitis5E-624024966
83847S-(3-hydroxypropyl)cysteine N-acetate6E-626053186
83848Smoking6E-626053186
85625Body Mass Index2E-623251661
86214Cognition Disorders2E-926252872
86215Cognitive Dysfunction2E-926252872
86251Glaucoma4E-825027321
87923Glaucoma1E-825027321
88138Hyperopia5E-725233373
88887Phospholipids5E-719043545
91983Subcutaneous Fat9E-622589738
92309Phospholipids1E-822359512
94958Antipsychotic Agents2E-619875103
95484Schizophrenia7E-726198764
97140Schizophrenia1E-726198764
97993Alzheimer Disease4E-1026830138
97994Age of Onset4E-1026830138
98291Severe Dengue2E-722001756
99268Neuroticism8E-627089181
100224Body Composition9E-623251661
100835Myopia2E-6327182965
102132Sleep4E-623728906
103270Age-Related Hearing Impairment 14E-924939585
104088Adipose Tissue2E-722589738
104089Body Mass Index2E-722589738

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000078328homo_sapiensENSP0000051039571.587766.8524homo_sapiensENSP0000045003164.735560.4534
ENSG00000078328homo_sapiensENSP0000051221961.297556.5996homo_sapiensENSP0000045003169.017663.728

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000078328homo_sapiensENSP0000045003187.405585.6423nomascus_leucogenysENSNLEP0000004142859.62258.4192
ENSG00000078328homo_sapiensENSP0000045003187.405585.8942pan_paniscusENSPPAP0000002649959.62258.5911
ENSG00000078328homo_sapiensENSP0000045003187.405585.8942pongo_abeliiENSPPYP0000003671659.62258.5911
ENSG00000078328homo_sapiensENSP0000045003187.405585.8942pan_troglodytesENSPTRP0000008511159.62258.5911
ENSG00000078328homo_sapiensENSP0000045003187.405585.8942gorilla_gorillaENSGGOP0000004556161.743860.6762
ENSG00000078328homo_sapiensENSP0000045003184.13182.6196ornithorhynchus_anatinusENSOANP0000000377178.220176.815
ENSG00000078328homo_sapiensENSP0000045003197.984996.9773sarcophilus_harrisiiENSSHAP0000002369470.090169.3694
ENSG00000078328homo_sapiensENSP0000045003178.337576.8262notamacropus_eugeniiENSMEUP0000001141774.580373.1415
ENSG00000078328homo_sapiensENSP0000045003174.055472.2922choloepus_hoffmanniENSCHOP0000001138170.503668.8249
ENSG00000078328homo_sapiensENSP0000045003197.73396.9773dasypus_novemcinctusENSDNOP0000002685493.49492.7711
ENSG00000078328homo_sapiensENSP0000045003176.070574.0554echinops_telfairiENSETEP0000000309472.422170.5036
ENSG00000078328homo_sapiensENSP0000045003187.153785.3904callithrix_jacchusENSCJAP0000005960360.489559.2657
ENSG00000078328homo_sapiensENSP0000045003187.405585.8942cercocebus_atysENSCATP0000002058559.930958.8946
ENSG00000078328homo_sapiensENSP0000045003187.153785.3904macaca_fascicularisENSMFAP0000003624259.861658.6505
ENSG00000078328homo_sapiensENSP0000045003184.634880.6045macaca_mulattaENSMMUP0000000460878.504774.7664
ENSG00000078328homo_sapiensENSP0000045003187.405585.6423macaca_nemestrinaENSMNEP0000001631659.930958.7219
ENSG00000078328homo_sapiensENSP0000045003187.405585.8942papio_anubisENSPANP0000003679059.930958.8946
ENSG00000078328homo_sapiensENSP0000045003187.405585.8942mandrillus_leucophaeusENSMLEP0000000358778.153276.8018
ENSG00000078328homo_sapiensENSP0000045003195.717994.4584tursiops_truncatusENSTTRP0000000538190.909189.7129
ENSG00000078328homo_sapiensENSP0000045003197.481196.9773vulpes_vulpesENSVVUP0000002362788.761588.3027
ENSG00000078328homo_sapiensENSP0000045003195.717993.9547mus_spretusMGP_SPRETEiJ_P004211891.127189.4484
ENSG00000078328homo_sapiensENSP0000045003187.153785.3904equus_asinusENSEASP0000501675774.248972.7468
ENSG00000078328homo_sapiensENSP0000045003192.443391.4358capra_hircusENSCHIP0000002779890.394189.4089
ENSG00000078328homo_sapiensENSP0000045003175.818675.063loxodonta_africanaENSLAFP0000000959497.727396.7533
ENSG00000078328homo_sapiensENSP0000045003186.901885.1385panthera_leoENSPLOP0000001537374.034372.5322
ENSG00000078328homo_sapiensENSP0000045003186.901885.3904ailuropoda_melanoleucaENSAMEP0000003475059.585558.5492
ENSG00000078328homo_sapiensENSP0000045003187.909386.398bos_indicus_hybridENSBIXP0000503077480.414779.0323
ENSG00000078328homo_sapiensENSP0000045003178.337574.3073oryctolagus_cuniculusENSOCUP0000000104584.281879.9458
ENSG00000078328homo_sapiensENSP0000045003184.13182.8715equus_caballusENSECAP0000001092663.018962.0755
ENSG00000078328homo_sapiensENSP0000045003187.153785.6423canis_lupus_familiarisENSCAFP0084502220059.758258.7219
ENSG00000078328homo_sapiensENSP0000045003186.901885.1385panthera_pardusENSPPRP0000001252159.585558.3765
ENSG00000078328homo_sapiensENSP0000045003195.717994.4584marmota_marmota_marmotaENSMMMP0000000642090.909189.7129
ENSG00000078328homo_sapiensENSP0000045003186.901885.1385balaenoptera_musculusENSBMSP0001003009859.688658.4775
ENSG00000078328homo_sapiensENSP0000045003195.969894.2066cavia_porcellusENSCPOP0000002415791.148389.4737
ENSG00000078328homo_sapiensENSP0000045003186.901885.1385felis_catusENSFCAP0000004372459.585558.3765
ENSG00000078328homo_sapiensENSP0000045003182.619681.3602ursus_americanusENSUAMP0000003223176.279175.1163
ENSG00000078328homo_sapiensENSP0000045003194.710393.199monodelphis_domesticaENSMODP0000004893288.888987.4705
ENSG00000078328homo_sapiensENSP0000045003186.901885.1385bison_bison_bisonENSBBBP0000002485859.278458.0756
ENSG00000078328homo_sapiensENSP0000045003186.649984.8867monodon_monocerosENSMMNP0001500668159.515658.3045
ENSG00000078328homo_sapiensENSP0000045003198.740698.4887sus_scrofaENSSSCP0000007666452.127751.9947
ENSG00000078328homo_sapiensENSP0000045003178.841377.0781microcebus_murinusENSMICP0000004717566.173464.6934
ENSG00000078328homo_sapiensENSP0000045003196.473593.9547octodon_degusENSODEP0000001784791.626889.2345
ENSG00000078328homo_sapiensENSP0000045003192.695290.932jaculus_jaculusENSJJAP0000000183790.196188.4804
ENSG00000078328homo_sapiensENSP0000045003193.954791.9395ovis_aries_rambouilletENSOARP0002001590266.845965.4122
ENSG00000078328homo_sapiensENSP0000045003171.536570.0252ursus_maritimusENSUMAP0000000444079.108677.4373
ENSG00000078328homo_sapiensENSP0000045003177.3376.0705ochotona_princepsENSOPRP0000000568773.621172.4221
ENSG00000078328homo_sapiensENSP0000045003196.977396.4735delphinapterus_leucasENSDLEP0000002193982.26581.8376
ENSG00000078328homo_sapiensENSP0000045003186.901885.1385physeter_catodonENSPCTP0000501158159.688658.4775
ENSG00000078328homo_sapiensENSP0000045003195.969894.4584mus_caroliMGP_CAROLIEiJ_P004027591.366989.9281
ENSG00000078328homo_sapiensENSP0000045003195.969894.2066mus_musculusENSMUSP0000015536491.366989.6882
ENSG00000078328homo_sapiensENSP0000045003192.947191.6877dipodomys_ordiiENSDORP0000002401888.277587.0813
ENSG00000078328homo_sapiensENSP0000045003183.627282.8715mustela_putorius_furoENSMPUP0000001471284.26483.5025
ENSG00000078328homo_sapiensENSP0000045003187.405585.6423aotus_nancymaaeENSANAP0000002406859.930958.7219
ENSG00000078328homo_sapiensENSP0000045003187.405585.3904saimiri_boliviensis_boliviensisENSSBOP0000003528468.172966.6012
ENSG00000078328homo_sapiensENSP0000045003176.070575.063vicugna_pacosENSVPAP0000000118372.248871.2919
ENSG00000078328homo_sapiensENSP0000045003184.13183.3753chlorocebus_sabaeusENSCSAP0000000499488.829888.0319
ENSG00000078328homo_sapiensENSP0000045003158.690257.6826tupaia_belangeriENSTBEP0000000794455.741654.7847
ENSG00000078328homo_sapiensENSP0000045003156.92753.6524mesocricetus_auratusENSMAUP0000002341576.610272.2034
ENSG00000078328homo_sapiensENSP0000045003186.39884.8867phocoena_sinusENSPSNP0000001264959.342658.3045
ENSG00000078328homo_sapiensENSP0000045003185.138582.6196camelus_dromedariusENSCDRP0000501443972.222270.0855
ENSG00000078328homo_sapiensENSP0000045003186.39884.8867carlito_syrichtaENSTSYP0000002772782.850281.401
ENSG00000078328homo_sapiensENSP0000045003171.032767.2544panthera_tigris_altaicaENSPTIP0000002538166.666763.1206
ENSG00000078328homo_sapiensENSP0000045003188.413186.1461rattus_norvegicusENSRNOP0000007078887.313485.0746
ENSG00000078328homo_sapiensENSP0000045003185.894284.3829prolemur_simusENSPSMP0000002988976.286474.9441
ENSG00000078328homo_sapiensENSP0000045003195.717994.2066microtus_ochrogasterENSMOCP0000002455291.127189.6882
ENSG00000078328homo_sapiensENSP0000045003139.546638.2872sorex_araneusENSSARP0000000450765.690463.5983
ENSG00000078328homo_sapiensENSP0000045003195.969894.4584peromyscus_maniculatus_bairdiiENSPEMP0000001927691.366989.9281
ENSG00000078328homo_sapiensENSP0000045003177.3375.5667bos_mutusENSBMUP0000002658871.72970.0935
ENSG00000078328homo_sapiensENSP0000045003197.481196.2217mus_spicilegusENSMSIP0000002800992.142990.9524
ENSG00000078328homo_sapiensENSP0000045003195.969894.2066cricetulus_griseus_chok1gshdENSCGRP0000101229691.366989.6882
ENSG00000078328homo_sapiensENSP0000045003192.191490.4282pteropus_vampyrusENSPVAP0000001270587.559885.8852
ENSG00000078328homo_sapiensENSP0000045003177.078177.0781myotis_lucifugusENSMLUP0000001448599.674399.6743
ENSG00000078328homo_sapiensENSP0000045003184.382982.6196vombatus_ursinusENSVURP0001001396271.428669.936
ENSG00000078328homo_sapiensENSP0000045003186.39884.6348rhinolophus_ferrumequinumENSRFEP0001003111159.240158.0311
ENSG00000078328homo_sapiensENSP0000045003186.901885.3904neovison_visonENSNVIP0000000090359.482858.4483
ENSG00000078328homo_sapiensENSP0000045003195.717994.4584bos_taurusENSBTAP000000697839593.75
ENSG00000078328homo_sapiensENSP0000045003197.481196.4735heterocephalus_glaber_femaleENSHGLP0000005408688.761587.844
ENSG00000078328homo_sapiensENSP0000045003186.649985.6423rhinopithecus_bietiENSRBIP0000004241783.091882.1256
ENSG00000078328homo_sapiensENSP0000045003171.788470.7809canis_lupus_dingoENSCAFP0002003192479.831978.7115
ENSG00000078328homo_sapiensENSP0000045003186.39884.3829sciurus_vulgarisENSSVLP0000502943159.652258.2609
ENSG00000078328homo_sapiensENSP0000045003184.382982.6196phascolarctos_cinereusENSPCIP0000003644971.428669.936
ENSG00000078328homo_sapiensENSP0000045003178.337577.0781procavia_capensisENSPCAP0000000248182.275180.9524
ENSG00000078328homo_sapiensENSP0000045003195.717994.7103nannospalax_galiliENSNGAP0000002527190.909189.9522
ENSG00000078328homo_sapiensENSP0000045003190.428289.1688bos_grunniensENSBGRP0000001597379.424878.3186
ENSG00000078328homo_sapiensENSP0000045003196.221794.7103chinchilla_lanigeraENSCLAP0000001860391.387689.9522
ENSG00000078328homo_sapiensENSP0000045003186.649984.8867cervus_hanglu_yarkandensisENSCHYP0000000667559.515658.3045
ENSG00000078328homo_sapiensENSP0000045003186.39884.3829catagonus_wagneriENSCWAP0000002731673.605171.8884
ENSG00000078328homo_sapiensENSP0000045003195.46693.9547ictidomys_tridecemlineatusENSSTOP0000000028890.669989.2345
ENSG00000078328homo_sapiensENSP0000045003198.488797.9849otolemur_garnettiiENSOGAP0000001815598.488797.9849
ENSG00000078328homo_sapiensENSP0000045003187.405585.6423cebus_imitatorENSCCAP0000001072781.074879.4393
ENSG00000078328homo_sapiensENSP0000045003195.717994.4584urocitellus_parryiiENSUPAP0001002493990.909189.7129
ENSG00000078328homo_sapiensENSP0000045003186.39884.6348moschus_moschiferusENSMMSP0000001541273.605172.103
ENSG00000078328homo_sapiensENSP0000045003187.405585.8942rhinopithecus_roxellanaENSRROP0000004263159.62258.5911
ENSG00000078328homo_sapiensENSP0000045003195.969894.4584mus_pahariMGP_PahariEiJ_P002767491.366989.9281
ENSG00000078328homo_sapiensENSP0000045003187.153785.3904propithecus_coquereliENSPCOP0000002662174.248972.7468
ENSG00000078328homo_sapiensENSP0000045003144.080634.2569caenorhabditis_elegansT07D1.4d.140.792531.7016
ENSG00000078328homo_sapiensENSP0000045003149.118442.0655drosophila_melanogasterFBpp029363020.270317.3597
ENSG00000078328homo_sapiensENSP0000045003147.607140.5542ciona_intestinalisENSCINP0000002534142.187535.9375
ENSG00000078328homo_sapiensENSP0000045003173.299864.9874callorhinchus_miliiENSCMIP0000003457274.234765.8163
ENSG00000078328homo_sapiensENSP0000045003189.924486.398lepisosteus_oculatusENSLOCP0000000806589.698586.1809
ENSG00000078328homo_sapiensENSP0000045003172.040369.0176clupea_harengusENSCHAP0000004658173.711370.6186
ENSG00000078328homo_sapiensENSP0000045003183.879180.8564danio_rerioENSDARP0000010709989.276186.059
ENSG00000078328homo_sapiensENSP0000045003178.085672.796carassius_auratusENSCARP0000000139073.459768.4834
ENSG00000078328homo_sapiensENSP0000045003182.619680.3526carassius_auratusENSCARP0000007612077.909775.772
ENSG00000078328homo_sapiensENSP0000045003155.163746.3476astyanax_mexicanusENSAMXP0000003530959.67350.1362
ENSG00000078328homo_sapiensENSP0000045003179.848976.5743ictalurus_punctatusENSIPUP0000002245184.084980.6366
ENSG00000078328homo_sapiensENSP0000045003175.566768.7657esox_luciusENSELUP0000004455574.074167.4074
ENSG00000078328homo_sapiensENSP0000045003183.123479.3451electrophorus_electricusENSEEEP0000004310285.937582.0312
ENSG00000078328homo_sapiensENSP0000045003175.06368.262oncorhynchus_mykissENSOMYP0000012431881.198973.842
ENSG00000078328homo_sapiensENSP0000045003153.400546.0957oncorhynchus_mykissENSOMYP0000013792454.922347.4093
ENSG00000078328homo_sapiensENSP0000045003182.367876.8262salmo_salarENSSSAP0000012298086.737480.9019
ENSG00000078328homo_sapiensENSP0000045003174.811169.2695salmo_salarENSSSAP0000013024782.576.3889
ENSG00000078328homo_sapiensENSP0000045003131.73825.6927salmo_truttaENSSTUP0000004868664.615452.3077
ENSG00000078328homo_sapiensENSP0000045003156.92752.8967gadus_morhuaENSGMOP0000004178184.014978.0669
ENSG00000078328homo_sapiensENSP0000045003159.445853.9043gadus_morhuaENSGMOP0000003847377.377170.1639
ENSG00000078328homo_sapiensENSP0000045003176.574371.0327cyclopterus_lumpusENSCLMP0000502745784.210578.1163
ENSG00000078328homo_sapiensENSP0000045003158.186449.1184oreochromis_niloticusENSONIP0000004413567.151256.686
ENSG00000078328homo_sapiensENSP0000045003183.375377.5819sparus_aurataENSSAUP0001003025780.535374.9392
ENSG00000078328homo_sapiensENSP0000045003172.292267.0025lates_calcariferENSLCAP0001002129381.766475.7835
ENSG00000078328homo_sapiensENSP0000045003186.901884.6348xenopus_tropicalisENSXETP0000010807376.666774.6667
ENSG00000078328homo_sapiensENSP0000045003181.360279.3451chrysemys_picta_belliiENSCPBP0000003852478.208276.2712
ENSG00000078328homo_sapiensENSP0000045003175.314971.7884sphenodon_punctatusENSSPUP0000001265184.225380.2817
ENSG00000078328homo_sapiensENSP0000045003174.559271.5365crocodylus_porosusENSCPRP0000500487477.284674.1514
ENSG00000078328homo_sapiensENSP0000045003189.420786.1461notechis_scutatusENSNSUP0000001164794.666791.2
ENSG00000078328homo_sapiensENSP0000045003164.483661.461pseudonaja_textilisENSPTXP0000000854378.527674.8466
ENSG00000078328homo_sapiensENSP0000045003194.962292.6952anas_platyrhynchos_platyrhynchosENSAPLP0000002459490.407788.2494
ENSG00000078328homo_sapiensENSP0000045003187.405584.131gallus_gallusENSGALP0001002735177.111174.2222
ENSG00000078328homo_sapiensENSP0000045003191.939589.4207serinus_canariaENSSCAP0000001631089.242186.7971
ENSG00000078328homo_sapiensENSP0000045003195.214193.199parus_majorENSPMJP0000001359686.697384.8624
ENSG00000078328homo_sapiensENSP0000045003134.256929.7229anolis_carolinensisENSACAP0000003713180.952470.2381
ENSG00000078328homo_sapiensENSP0000045003170.52961.461neolamprologus_brichardiENSNBRP0000001436366.825858.2339
ENSG00000078328homo_sapiensENSP0000045003173.551670.0252naja_najaENSNNAP000000253538076.1644
ENSG00000078328homo_sapiensENSP0000045003194.962292.1914podarcis_muralisENSPMRP0000002819086.467983.945
ENSG00000078328homo_sapiensENSP0000045003194.962292.6952geospiza_fortisENSGFOP0000001270290.407788.2494
ENSG00000078328homo_sapiensENSP0000045003181.360279.3451taeniopygia_guttataENSTGUP0000002174078.208276.2712
ENSG00000078328homo_sapiensENSP0000045003185.642383.6272erpetoichthys_calabaricusENSECRP0000002670392.140989.9729
ENSG00000078328homo_sapiensENSP0000045003191.183988.4131salvator_merianaeENSSMRP0000002186096.021293.1034
ENSG00000078328homo_sapiensENSP0000045003160.957253.4005amphilophus_citrinellusENSACIP0000000698961.111153.5354
ENSG00000078328homo_sapiensENSP0000045003184.13178.3375dicentrarchus_labraxENSDLAP0000501912381.265275.6691
ENSG00000078328homo_sapiensENSP0000045003165.239357.4307amphiprion_perculaENSAPEP0000001513671.745263.1579
ENSG00000078328homo_sapiensENSP0000045003194.710392.6952pelodiscus_sinensisENSPSIP0000000705994.235692.2306
ENSG00000078328homo_sapiensENSP0000045003193.19990.4282gopherus_evgoodeiENSGEVP0000501743788.516785.8852
ENSG00000078328homo_sapiensENSP0000045003177.833875.5667chelonoidis_abingdoniiENSCABP0000001824679.84577.5194
ENSG00000078328homo_sapiensENSP0000045003177.581972.5441seriola_dumeriliENSSDUP0000002263584.615479.1209
ENSG00000078328homo_sapiensENSP0000045003183.879177.8338cottoperca_gobioENSCGOP0000000338181.021975.1825
ENSG00000078328homo_sapiensENSP0000045003194.710392.6952struthio_camelus_australisENSSCUP0000002209186.436884.5977
ENSG00000078328homo_sapiensENSP0000045003194.962292.6952anser_brachyrhynchusENSABRP0000002538393.781191.5423
ENSG00000078328homo_sapiensENSP0000045003176.826270.529cynoglossus_semilaevisENSCSEP0000001372782.432475.6757
ENSG00000078328homo_sapiensENSP0000045003180.604575.063myripristis_murdjanENSMMDP0000503628582.687377.0026
ENSG00000078328homo_sapiensENSP0000045003177.581972.0403sander_luciopercaENSSLUP0000002547587.005780.791
ENSG00000078328homo_sapiensENSP0000045003194.962292.9471strigops_habroptilaENSSHBP0000500227590.407788.4892
ENSG00000078328homo_sapiensENSP0000045003159.697754.4081amphiprion_ocellarisENSAOCP0000002268081.164473.9726
ENSG00000078328homo_sapiensENSP0000045003193.450990.6801terrapene_carolina_triunguisENSTMTP0000000090388.75686.1244
ENSG00000078328homo_sapiensENSP0000045003129.722923.6776hucho_huchoENSHHUP0000006886176.623461.039
ENSG00000078328homo_sapiensENSP0000045003182.871581.1083pygocentrus_nattereriENSPNAP0000003407589.159987.2629
ENSG00000078328homo_sapiensENSP0000045003176.826271.7884anabas_testudineusENSATEP0000006326285.915580.2817
ENSG00000078328homo_sapiensENSP0000045003133.249427.7078ciona_savignyiENSCSAVP0000000980546.808539.0071
ENSG00000078328homo_sapiensENSP0000045003164.987459.6977seriola_lalandi_dorsalisENSSLDP0000001181376.106269.9115
ENSG00000078328homo_sapiensENSP0000045003179.59772.2922labrus_bergyltaENSLBEP0000001916281.865374.3523
ENSG00000078328homo_sapiensENSP0000045003181.86475.063mastacembelus_armatusENSMAMP0000000465683.333376.4103
ENSG00000078328homo_sapiensENSP0000045003182.367877.33stegastes_partitusENSSPAP0000001299687.281.8667
ENSG00000078328homo_sapiensENSP0000045003184.13178.0856acanthochromis_polyacanthusENSAPOP0000000184281.265275.4258
ENSG00000078328homo_sapiensENSP0000045003194.962292.9471aquila_chrysaetos_chrysaetosENSACCP0002001775490.407788.4892
ENSG00000078328homo_sapiensENSP0000045003184.634881.6121denticeps_clupeoidesENSDCDP0000005322282.758679.803
ENSG00000078328homo_sapiensENSP0000045003184.13178.5894larimichthys_croceaENSLCRP0000504702883.291877.8055
ENSG00000078328homo_sapiensENSP0000045003172.292263.9799takifugu_rubripesENSTRUP0000006073468.824960.9113
ENSG00000078328homo_sapiensENSP0000045003194.962292.6952ficedula_albicollisENSFALP0000002747690.407788.2494
ENSG00000078328homo_sapiensENSP0000045003169.521462.4685hippocampus_comesENSHCOP0000001327280.232672.093
ENSG00000078328homo_sapiensENSP0000045003177.833874.0554cyprinus_carpio_carpioENSCCRP0000010089865.052661.8947
ENSG00000078328homo_sapiensENSP0000045003183.879181.6121cyprinus_carpio_carpioENSCCRP0000003358987.631685.2632
ENSG00000078328homo_sapiensENSP0000045003194.710392.6952coturnix_japonicaENSCJPP0000501988187.03785.1852
ENSG00000078328homo_sapiensENSP0000045003181.360278.5894sinocyclocheilus_grahamiENSSGRP0000009686389.473786.4266
ENSG00000078328homo_sapiensENSP0000045003185.138581.864sinocyclocheilus_grahamiENSSGRP0000002256385.786882.4873
ENSG00000078328homo_sapiensENSP0000045003148.614646.5995tetraodon_nigroviridisENSTNIP0000000511875.686372.549
ENSG00000078328homo_sapiensENSP0000045003183.879179.8489paramormyrops_kingsleyaeENSPKIP0000002779077.622473.8928
ENSG00000078328homo_sapiensENSP0000045003187.153783.8791scleropages_formosusENSSFOP0001505892385.012381.8182
ENSG00000078328homo_sapiensENSP0000045003177.078170.7809scophthalmus_maximusENSSMAP0000004533371.83165.9624

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0000381involved_in regulation of alternative mRNA splicing, via spliceosome1IBAHomo_sapiens(9606)Process
GO:0003723enables RNA binding1NASHomo_sapiens(9606)Function
GO:0003729enables mRNA binding1IBAHomo_sapiens(9606)Function
GO:0003730enables mRNA 3-UTR binding1IEAHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005634is_active_in nucleus1IBAHomo_sapiens(9606)Component
GO:0005737is_active_in cytoplasm2IBA,IDAHomo_sapiens(9606)Component
GO:0005802located_in trans-Golgi network1IDAHomo_sapiens(9606)Component
GO:0006397involved_in mRNA processing1IEAHomo_sapiens(9606)Process
GO:0007399involved_in nervous system development1IBAHomo_sapiens(9606)Process
GO:0008380involved_in RNA splicing1IEAHomo_sapiens(9606)Process
GO:0010494located_in cytoplasmic stress granule1IDAHomo_sapiens(9606)Component
GO:0050658involved_in RNA transport1NASHomo_sapiens(9606)Process
GO:0050885involved_in neuromuscular process controlling balance1IEAHomo_sapiens(9606)Process
GO:0097165located_in nuclear stress granule1IDAHomo_sapiens(9606)Component
GO:2001014involved_in regulation of skeletal muscle cell differentiation1IEAHomo_sapiens(9606)Process

Expression