RBP Type	Non-canonical_RBPs
Diseases	CancerSARS-COV-2
Drug	N.A.
Main interacting RNAs	N.A.
Moonlighting functions	Metabolic enzyme
Localizations	N.A.
BulkPerturb-seq	N.A.

Ensembl ID	ENSG00000074800	Gene ID	2023	Accession	3350
Symbol	ENO1	Alias	NNE;PPH;MPB1;ENO1L1;ENO1-IT1;HEL-S-17	Full Name	enolase 1
Status	Confidence	Length	18191 bases	Strand	Minus strand
Position	1 : 8861000 - 8879190	RNA binding domain	N.A.
Summary	This gene encodes alpha-enolase, one of three enolase isoenzymes found in mammals. Each isoenzyme is a homodimer composed of 2 alpha, 2 gamma, or 2 beta subunits, and functions as a glycolytic enzyme. Alpha-enolase in addition, functions as a structural lens protein (tau-crystallin) in the monomeric form. Alternative splicing of this gene results in a shorter isoform that has been shown to bind to the c-myc promoter and function as a tumor suppressor. Several pseudogenes have been identified, including one on the long arm of chromosome 1. Alpha-enolase has also been identified as an autoantigen in Hashimoto encephalopathy. [provided by RefSeq, Jan 2011]