RBP Type
Canonical_RBPs
Diseases
SARS-COV-OC43 Flaviviruses HIV RV SARS-COV-2 SINV Dengue Zika
Drug
N.A.
Main interacting RNAs
mRNA
Moonlighting functions
N.A.
Localizations
Stress granule or P-body
BulkPerturb-seq
Ensembl ID ENSG00000063244 Gene ID
11338 Accession
23156
Symbol
U2AF2
Alias
U2AF65
Full Name
U2 small nuclear RNA auxiliary factor 2
Status
Confidence
Length
20571 bases
Strand
Plus strand
Position
19 : 55654146 - 55674716
RNA binding domain
RRM_1
Summary
U2 auxiliary factor (U2AF), comprised of a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. This gene encodes the U2AF large subunit which contains a sequence-specific RNA-binding region with 3 RNA recognition motifs and an Arg/Ser-rich domain necessary for splicing. The large subunit binds to the polypyrimidine tract of introns early during spliceosome assembly. Multiple transcript variants have been detected for this gene, but the full-length natures of only two have been determined to date. [provided by RefSeq, Jul 2008]
RNA binding domains (RBDs)
Protein
Domain
Pfam ID
E-value
Domain number
ENSP00000388475
RRM_1
PF00076 1e-33
1
ENSP00000388475
RRM_1
PF00076 1e-33
2
ENSP00000388475
RRM_1
PF00076 1e-33
3
ENSP00000307863
RRM_1
PF00076 1.1e-33
1
ENSP00000307863
RRM_1
PF00076 1.1e-33
2
ENSP00000307863
RRM_1
PF00076 1.1e-33
3
RNA binding proteomes (RBPomes)
Pubmed ID
Full Name
Cell
Author
Time
Doi
Literatures on RNA binding capacity
Pubmed ID
Title
Author
Time
Journal
34543356 The HTLV-1 viral oncoproteins Tax and HBZ reprogram the cellular mRNA splicing landscape.
Charlotte Vandermeulen
2021-09-01
PLoS pathogens
28050347 Gene expression profiling of U2AF2 dependent RNA-protein interactions during CD4 + T cell activation.
C Thomas Whisenant
2017-03-01
Genomics data
36338673 The genetics of myelodysplastic syndromes and the opportunities for tailored treatments.
Christina-Nefeli Kontandreopoulou
2022-01-01
Frontiers in oncology
33217981 Role of CCCH-Type Zinc Finger Proteins in Human Adenovirus Infections.
Zamaneh Hajikhezri
2020-11-18
Viruses
26566657 RNA structure replaces the need for U2AF2 in splicing.
Chien-Ling Lin
2016-01-01
Genome research
31474574 Disease-Causing Mutations in SF3B1 Alter Splicing by Disrupting Interaction with SUGP1.
Jian Zhang
2019-10-03
Molecular cell
35252867 Transcriptional regulators of human oncoviruses: structural and functional implications for anticancer therapy.
Ivona Nečasová
2022-03-01
NAR cancer
22594801 Defects in spliceosomal machinery: a new pathway of leukaemogenesis.
P Jaroslaw Maciejewski
2012-07-01
British journal of haematology
26641092 The Activation-Induced Assembly of an RNA/Protein Interactome Centered on the Splicing Factor U2AF2 Regulates Gene Expression in Human CD4 T Cells.
C Thomas Whisenant
2015-01-01
PloS one
27240813 Lessons from non-canonical splicing.
R Christopher Sibley
2016-07-01
Nature reviews. Genetics
34926310 Ferroptosis in Lung Cancer: From Molecular Mechanisms to Prognostic and Therapeutic Opportunities.
Peyman Tabnak
2021-01-01
Frontiers in oncology
29643205 In vitro iCLIP-based modeling uncovers how the splicing factor U2AF2 relies on regulation by cofactors.
Reymond X F Sutandy
2018-05-01
Genome research
36635261 The U2AF65/circNCAPG/RREB1 feedback loop promotes malignant phenotypes of glioma stem cells through activating the TGF-β pathway.
Hao Li
2023-01-13
Cell death & disease
29921876 Nuclear PTEN safeguards pre-mRNA splicing to link Golgi apparatus for its tumor suppressive role.
Shao-Ming Shen
2018-06-19
Nature communications
35524551 Pre-mRNA splicing factor U2AF2 recognizes distinct conformations of nucleotide variants at the center of the pre-mRNA splice site signal.
Eliezra Glasser
2022-05-20
Nucleic acids research
33020180 Representative cancer-associated U2AF2 mutations alter RNA interactions and splicing.
Debanjana Maji
2020-12-11
The Journal of biological chemistry
33689684 A synthetic small molecule stalls pre-mRNA splicing by promoting an early-stage U2AF2-RNA complex.
Rakesh Chatrikhi
2021-08-19
Cell chemical biology
28850223 Cancer-Associated Mutations Mapped on High-Resolution Structures of the U2AF2 RNA Recognition Motifs.
Eliezra Glasser
2017-09-12
Biochemistry
Name
Transcript ID
bp
Protein
Translation ID
U2AF2-202
ENST00000450554
3022
471aa
ENSP00000388475
U2AF2-207
ENST00000592874
3067
162aa
ENSP00000466167
U2AF2-201
ENST00000308924
2146
475aa
ENSP00000307863
U2AF2-205
ENST00000588850
637
No protein
-
U2AF2-203
ENST00000587196
778
51aa
ENSP00000470020
U2AF2-206
ENST00000592867
447
No protein
-
U2AF2-204
ENST00000587275
554
No protein
-
Pathway ID
Pathway Name
Source
ensgID
Trait
pValue
Pubmed ID
96689 S-(3-hydroxypropyl)cysteine N-acetate 10E-7 26053186 96690 Smoking 10E-7 26053186
ensgID SNP Chromosome Position
Trait PubmedID Or or BEAT
EFO ID
Protein-Protein Interaction (PPI)
Ensembl ID
Source
Target
Species
Protein ID
Perc_pos
Perc_id
Species
Protein ID
Perc_pos
Perc_id
ENSG00000063244 homo_sapiens ENSP00000362063 20.9705 11.7851 homo_sapiens ENSP00000307863 25.4737 14.3158 ENSG00000063244 homo_sapiens ENSP00000266529 34.1014 18.894 homo_sapiens ENSP00000307863 15.5789 8.63158 ENSG00000063244 homo_sapiens ENSP00000339090 34.472 17.3913 homo_sapiens ENSP00000307863 23.3684 11.7895 ENSG00000063244 homo_sapiens ENSP00000332444 19.1558 10.8766 homo_sapiens ENSP00000307863 24.8421 14.1053 ENSG00000063244 homo_sapiens ENSP00000420270 40.3341 21.7184 homo_sapiens ENSP00000307863 35.5789 19.1579
Ensembl ID
Source
Target
Species
Protein ID
Perc_pos
Perc_id
Species
Protein ID
Perc_pos
Perc_id
ENSG00000063244 homo_sapiens ENSP00000307863 84.2105 81.8947 nomascus_leucogenys ENSNLEP00000012869 92.5926 90.0463 ENSG00000063244 homo_sapiens ENSP00000307863 100 100 pan_paniscus ENSPPAP00000033831 100 100 ENSG00000063244 homo_sapiens ENSP00000307863 99.1579 99.1579 pongo_abelii ENSPPYP00000011687 100 100 ENSG00000063244 homo_sapiens ENSP00000307863 100 100 pan_troglodytes ENSPTRP00000091126 100 100 ENSG00000063244 homo_sapiens ENSP00000307863 52.8421 52.6316 gorilla_gorilla ENSGGOP00000029775 99.2095 98.8142 ENSG00000063244 homo_sapiens ENSP00000307863 98.5263 98.1053 ornithorhynchus_anatinus ENSOANP00000053769 98.5263 98.1053 ENSG00000063244 homo_sapiens ENSP00000307863 98.9474 98.3158 sarcophilus_harrisii ENSSHAP00000031305 99.7877 99.1507 ENSG00000063244 homo_sapiens ENSP00000307863 80.4211 70.9474 sarcophilus_harrisii ENSSHAP00000023660 80.9322 71.3983 ENSG00000063244 homo_sapiens ENSP00000307863 84.4211 81.4737 notamacropus_eugenii ENSMEUP00000002133 88.326 85.2423 ENSG00000063244 homo_sapiens ENSP00000307863 90.9474 90.7368 dasypus_novemcinctus ENSDNOP00000021430 96.861 96.6368 ENSG00000063244 homo_sapiens ENSP00000307863 100 100 callithrix_jacchus ENSCJAP00000031483 100 100 ENSG00000063244 homo_sapiens ENSP00000307863 99.1579 99.1579 cercocebus_atys ENSCATP00000000957 100 100 ENSG00000063244 homo_sapiens ENSP00000307863 98.5263 98.5263 macaca_fascicularis ENSMFAP00000043089 100 100 ENSG00000063244 homo_sapiens ENSP00000307863 99.1579 99.1579 macaca_mulatta ENSMMUP00000006397 100 100 ENSG00000063244 homo_sapiens ENSP00000307863 99.1579 99.1579 macaca_nemestrina ENSMNEP00000038297 100 100 ENSG00000063244 homo_sapiens ENSP00000307863 100 100 papio_anubis ENSPANP00000010706 100 100 ENSG00000063244 homo_sapiens ENSP00000307863 97.0526 96.6316 mandrillus_leucophaeus ENSMLEP00000016041 90.0391 89.6484 ENSG00000063244 homo_sapiens ENSP00000307863 100 100 tursiops_truncatus ENSTTRP00000000930 100 100 ENSG00000063244 homo_sapiens ENSP00000307863 97.6842 97.0526 vulpes_vulpes ENSVVUP00000009334 67.9356 67.4963 ENSG00000063244 homo_sapiens ENSP00000307863 99.7895 99.7895 mus_spretus MGP_SPRETEiJ_P0080579 99.7895 99.7895 ENSG00000063244 homo_sapiens ENSP00000307863 100 100 equus_asinus ENSEASP00005046343 100 100 ENSG00000063244 homo_sapiens ENSP00000307863 79.7895 77.8947 capra_hircus ENSCHIP00000027856 88.9671 86.8545 ENSG00000063244 homo_sapiens ENSP00000307863 90.7368 85.4737 loxodonta_africana ENSLAFP00000019439 91.5074 86.1996 ENSG00000063244 homo_sapiens ENSP00000307863 99.3684 99.3684 loxodonta_africana ENSLAFP00000015135 99.3684 99.3684 ENSG00000063244 homo_sapiens ENSP00000307863 100 100 panthera_leo ENSPLOP00000023660 100 100 ENSG00000063244 homo_sapiens ENSP00000307863 96.4211 96.4211 ailuropoda_melanoleuca ENSAMEP00000004100 100 100 ENSG00000063244 homo_sapiens ENSP00000307863 90.3158 89.2632 bos_indicus_hybrid ENSBIXP00005016616 77.7174 76.8116 ENSG00000063244 homo_sapiens ENSP00000307863 96.8421 96.4211 equus_caballus ENSECAP00000072636 90.9091 90.5138 ENSG00000063244 homo_sapiens ENSP00000307863 100 100 canis_lupus_familiaris ENSCAFP00845000574 100 100 ENSG00000063244 homo_sapiens ENSP00000307863 100 100 panthera_pardus ENSPPRP00000023559 100 100 ENSG00000063244 homo_sapiens ENSP00000307863 99.1579 99.1579 marmota_marmota_marmota ENSMMMP00000001481 100 100 ENSG00000063244 homo_sapiens ENSP00000307863 100 100 balaenoptera_musculus ENSBMSP00010027507 100 100 ENSG00000063244 homo_sapiens ENSP00000307863 99.7895 99.7895 cavia_porcellus ENSCPOP00000001429 99.7895 99.7895 ENSG00000063244 homo_sapiens ENSP00000307863 93.6842 93.2632 ursus_americanus ENSUAMP00000025553 97.8022 97.3626 ENSG00000063244 homo_sapiens ENSP00000307863 44.8421 41.4737 monodelphis_domestica ENSMODP00000060218 73.1959 67.6976 ENSG00000063244 homo_sapiens ENSP00000307863 59.7895 59.5789 bison_bison_bison ENSBBBP00000022414 96.5986 96.2585 ENSG00000063244 homo_sapiens ENSP00000307863 100 100 monodon_monoceros ENSMMNP00015004498 100 100 ENSG00000063244 homo_sapiens ENSP00000307863 100 100 sus_scrofa ENSSSCP00000042718 100 100 ENSG00000063244 homo_sapiens ENSP00000307863 99.1579 99.1579 microcebus_murinus ENSMICP00000039337 100 100 ENSG00000063244 homo_sapiens ENSP00000307863 94.7368 94.7368 octodon_degus ENSODEP00000017278 99.7783 99.7783 ENSG00000063244 homo_sapiens ENSP00000307863 72.2105 68.2105 octodon_degus ENSODEP00000012485 85.5362 80.798 ENSG00000063244 homo_sapiens ENSP00000307863 99.7895 99.7895 jaculus_jaculus ENSJJAP00000015596 99.7895 99.7895 ENSG00000063244 homo_sapiens ENSP00000307863 87.7895 87.3684 ovis_aries_rambouillet ENSOARP00020004989 80.0384 79.6545 ENSG00000063244 homo_sapiens ENSP00000307863 93.6842 93.2632 ursus_maritimus ENSUMAP00000034166 97.8022 97.3626 ENSG00000063244 homo_sapiens ENSP00000307863 48.2105 48 ochotona_princeps ENSOPRP00000005631 50 49.7817 ENSG00000063244 homo_sapiens ENSP00000307863 96 96 delphinapterus_leucas ENSDLEP00000002377 100 100 ENSG00000063244 homo_sapiens ENSP00000307863 87.7895 87.1579 physeter_catodon ENSPCTP00005025238 96.3048 95.612 ENSG00000063244 homo_sapiens ENSP00000307863 99.7895 99.7895 mus_caroli MGP_CAROLIEiJ_P0077314 99.7895 99.7895 ENSG00000063244 homo_sapiens ENSP00000307863 99.7895 99.7895 mus_musculus ENSMUSP00000147013 99.7895 99.7895 ENSG00000063244 homo_sapiens ENSP00000307863 100 100 dipodomys_ordii ENSDORP00000003041 100 100 ENSG00000063244 homo_sapiens ENSP00000307863 99.1579 99.1579 mustela_putorius_furo ENSMPUP00000007078 100 100 ENSG00000063244 homo_sapiens ENSP00000307863 85.4737 85.4737 aotus_nancymaae ENSANAP00000020523 100 100 ENSG00000063244 homo_sapiens ENSP00000307863 99.1579 99.1579 saimiri_boliviensis_boliviensis ENSSBOP00000014257 100 100 ENSG00000063244 homo_sapiens ENSP00000307863 99.1579 99.1579 chlorocebus_sabaeus ENSCSAP00000016307 100 100 ENSG00000063244 homo_sapiens ENSP00000307863 74.1053 73.8947 tupaia_belangeri ENSTBEP00000007895 96.7033 96.4286 ENSG00000063244 homo_sapiens ENSP00000307863 97.0526 97.0526 mesocricetus_auratus ENSMAUP00000006164 98.5043 98.5043 ENSG00000063244 homo_sapiens ENSP00000307863 99.1579 99.1579 phocoena_sinus ENSPSNP00000023891 100 100 ENSG00000063244 homo_sapiens ENSP00000307863 99.3684 99.3684 camelus_dromedarius ENSCDRP00005013300 99.5781 99.5781 ENSG00000063244 homo_sapiens ENSP00000307863 100 100 carlito_syrichta ENSTSYP00000017949 100 100 ENSG00000063244 homo_sapiens ENSP00000307863 86.9474 84.8421 panthera_tigris_altaica ENSPTIP00000002519 89.3939 87.2294 ENSG00000063244 homo_sapiens ENSP00000307863 95.7895 95.7895 rattus_norvegicus ENSRNOP00000088416 98.4848 98.4848 ENSG00000063244 homo_sapiens ENSP00000307863 99.7895 99.7895 prolemur_simus ENSPSMP00000011212 99.7895 99.7895 ENSG00000063244 homo_sapiens ENSP00000307863 64 62.5263 microtus_ochrogaster ENSMOCP00000001330 99.0228 96.7427 ENSG00000063244 homo_sapiens ENSP00000307863 99.7895 99.7895 microtus_ochrogaster ENSMOCP00000013420 99.7895 99.7895 ENSG00000063244 homo_sapiens ENSP00000307863 91.7895 88.8421 microtus_ochrogaster ENSMOCP00000007424 95.4048 92.3414 ENSG00000063244 homo_sapiens ENSP00000307863 64.6316 64.6316 peromyscus_maniculatus_bairdii ENSPEMP00000005005 100 100 ENSG00000063244 homo_sapiens ENSP00000307863 86.1053 84.8421 bos_mutus ENSBMUP00000002105 92.3251 90.9707 ENSG00000063244 homo_sapiens ENSP00000307863 99.7895 99.7895 mus_spicilegus ENSMSIP00000015094 99.7895 99.7895 ENSG00000063244 homo_sapiens ENSP00000307863 94.1053 90.3158 cricetulus_griseus_chok1gshd ENSCGRP00001005666 95.3092 91.4712 ENSG00000063244 homo_sapiens ENSP00000307863 99.7895 99.7895 cricetulus_griseus_chok1gshd ENSCGRP00001002801 99.7895 99.7895 ENSG00000063244 homo_sapiens ENSP00000307863 99.7895 99.5789 pteropus_vampyrus ENSPVAP00000004298 99.7895 99.5789 ENSG00000063244 homo_sapiens ENSP00000307863 50.1053 49.6842 myotis_lucifugus ENSMLUP00000010071 98.7552 97.9253 ENSG00000063244 homo_sapiens ENSP00000307863 99.5789 98.9474 vombatus_ursinus ENSVURP00010003943 99.5789 98.9474 ENSG00000063244 homo_sapiens ENSP00000307863 100 100 rhinolophus_ferrumequinum ENSRFEP00010029520 100 100 ENSG00000063244 homo_sapiens ENSP00000307863 98.7368 98.7368 neovison_vison ENSNVIP00000015997 99.5754 99.5754 ENSG00000063244 homo_sapiens ENSP00000307863 99.5789 99.5789 bos_taurus ENSBTAP00000063486 99.5789 99.5789 ENSG00000063244 homo_sapiens ENSP00000307863 99.7895 99.7895 rhinopithecus_bieti ENSRBIP00000034687 99.7895 99.7895 ENSG00000063244 homo_sapiens ENSP00000307863 94.3158 94.3158 canis_lupus_dingo ENSCAFP00020019444 93.9203 93.9203 ENSG00000063244 homo_sapiens ENSP00000307863 100 100 sciurus_vulgaris ENSSVLP00005030750 100 100 ENSG00000063244 homo_sapiens ENSP00000307863 99.5789 98.9474 phascolarctos_cinereus ENSPCIP00000023819 99.5789 98.9474 ENSG00000063244 homo_sapiens ENSP00000307863 83.3684 83.3684 procavia_capensis ENSPCAP00000013460 83.1933 83.1933 ENSG00000063244 homo_sapiens ENSP00000307863 76 70.1053 procavia_capensis ENSPCAP00000003432 88.2641 81.4181 ENSG00000063244 homo_sapiens ENSP00000307863 99.5789 99.5789 nannospalax_galili ENSNGAP00000021080 99.5789 99.5789 ENSG00000063244 homo_sapiens ENSP00000307863 99.5789 99.5789 bos_grunniens ENSBGRP00000035556 99.5789 99.5789 ENSG00000063244 homo_sapiens ENSP00000307863 99.1579 99.1579 chinchilla_lanigera ENSCLAP00000000757 100 100 ENSG00000063244 homo_sapiens ENSP00000307863 94.3158 92.2105 cervus_hanglu_yarkandensis ENSCHYP00000028048 97.18 95.0108 ENSG00000063244 homo_sapiens ENSP00000307863 99.5789 99.5789 cervus_hanglu_yarkandensis ENSCHYP00000011716 99.5789 99.5789 ENSG00000063244 homo_sapiens ENSP00000307863 83.5789 81.4737 catagonus_wagneri ENSCWAP00000010582 88.4187 86.1915 ENSG00000063244 homo_sapiens ENSP00000307863 100 100 ictidomys_tridecemlineatus ENSSTOP00000018159 100 100 ENSG00000063244 homo_sapiens ENSP00000307863 100 100 otolemur_garnettii ENSOGAP00000006450 100 100 ENSG00000063244 homo_sapiens ENSP00000307863 65.0526 54.5263 otolemur_garnettii ENSOGAP00000017260 74.2788 62.2596 ENSG00000063244 homo_sapiens ENSP00000307863 100 100 cebus_imitator ENSCCAP00000011155 100 100 ENSG00000063244 homo_sapiens ENSP00000307863 88.4211 87.1579 urocitellus_parryii ENSUPAP00010002279 86.5979 85.3608 ENSG00000063244 homo_sapiens ENSP00000307863 99.5789 99.5789 moschus_moschiferus ENSMMSP00000026141 99.5789 99.5789 ENSG00000063244 homo_sapiens ENSP00000307863 97.0526 95.5789 moschus_moschiferus ENSMMSP00000025571 97.0526 95.5789 ENSG00000063244 homo_sapiens ENSP00000307863 94.7368 93.6842 rhinopithecus_roxellana ENSRROP00000014046 97.6139 96.5293 ENSG00000063244 homo_sapiens ENSP00000307863 86.9474 86.9474 rhinopithecus_roxellana ENSRROP00000013775 99.7585 99.7585 ENSG00000063244 homo_sapiens ENSP00000307863 99.7895 99.7895 mus_pahari MGP_PahariEiJ_P0045676 99.7895 99.7895 ENSG00000063244 homo_sapiens ENSP00000307863 100 100 propithecus_coquereli ENSPCOP00000026916 100 100 ENSG00000063244 homo_sapiens ENSP00000307863 68.8421 58.1053 caenorhabditis_elegans Y92C3B.2a.1 65.9274 55.6452 ENSG00000063244 homo_sapiens ENSP00000307863 75.7895 64.6316 drosophila_melanogaster FBpp0298005 84.3091 71.897 ENSG00000063244 homo_sapiens ENSP00000307863 64.4211 50.3158 drosophila_melanogaster FBpp0071961 68.1515 53.2294 ENSG00000063244 homo_sapiens ENSP00000307863 75.5789 64.6316 ciona_intestinalis ENSCINP00000007109 74.4813 63.6929 ENSG00000063244 homo_sapiens ENSP00000307863 81.2632 70.9474 petromyzon_marinus ENSPMAP00000004504 83.913 73.2609 ENSG00000063244 homo_sapiens ENSP00000307863 79.5789 69.8947 eptatretus_burgeri ENSEBUP00000017465 84 73.7778 ENSG00000063244 homo_sapiens ENSP00000307863 69.8947 57.8947 eptatretus_burgeri ENSEBUP00000002300 77.7518 64.4028 ENSG00000063244 homo_sapiens ENSP00000307863 25.4737 21.4737 eptatretus_burgeri ENSEBUP00000009327 84.6154 71.3287 ENSG00000063244 homo_sapiens ENSP00000307863 76.8421 76.2105 latimeria_chalumnae ENSLACP00000001847 99.455 98.6376 ENSG00000063244 homo_sapiens ENSP00000307863 67.7895 64.2105 lepisosteus_oculatus ENSLOCP00000009781 92.2636 87.3925 ENSG00000063244 homo_sapiens ENSP00000307863 92.2105 86.7368 clupea_harengus ENSCHAP00000004933 93.3902 87.8465 ENSG00000063244 homo_sapiens ENSP00000307863 92.6316 87.5789 clupea_harengus ENSCHAP00000045489 91.0973 86.1284 ENSG00000063244 homo_sapiens ENSP00000307863 92.2105 86.1053 danio_rerio ENSDARP00000023679 92.2105 86.1053 ENSG00000063244 homo_sapiens ENSP00000307863 91.5789 87.3684 danio_rerio ENSDARP00000002857 93.5484 89.2473 ENSG00000063244 homo_sapiens ENSP00000307863 90.1053 83.7895 carassius_auratus ENSCARP00000053574 89.1667 82.9167 ENSG00000063244 homo_sapiens ENSP00000307863 92 86.7368 carassius_auratus ENSCARP00000070184 93.177 87.8465 ENSG00000063244 homo_sapiens ENSP00000307863 89.8947 85.4737 carassius_auratus ENSCARP00000093508 92.8261 88.2609 ENSG00000063244 homo_sapiens ENSP00000307863 88.8421 84.6316 carassius_auratus ENSCARP00000063888 89.4068 85.1695 ENSG00000063244 homo_sapiens ENSP00000307863 92 86.9474 astyanax_mexicanus ENSAMXP00000052965 92.9787 87.8723 ENSG00000063244 homo_sapiens ENSP00000307863 91.7895 86.1053 astyanax_mexicanus ENSAMXP00000043126 94.1685 88.3369 ENSG00000063244 homo_sapiens ENSP00000307863 91.7895 86.7368 ictalurus_punctatus ENSIPUP00000013336 89.1616 84.2536 ENSG00000063244 homo_sapiens ENSP00000307863 90.1053 85.2632 ictalurus_punctatus ENSIPUP00000011355 92.4406 87.473 ENSG00000063244 homo_sapiens ENSP00000307863 93.0526 88.2105 esox_lucius ENSELUP00000015945 92.2756 87.4739 ENSG00000063244 homo_sapiens ENSP00000307863 89.6842 83.5789 esox_lucius ENSELUP00000023413 90.0634 83.9324 ENSG00000063244 homo_sapiens ENSP00000307863 91.5789 87.7895 electrophorus_electricus ENSEEEP00000026354 90.8142 87.0564 ENSG00000063244 homo_sapiens ENSP00000307863 92 88 electrophorus_electricus ENSEEEP00000013336 94.3845 90.2808 ENSG00000063244 homo_sapiens ENSP00000307863 88.8421 83.1579 oncorhynchus_kisutch ENSOKIP00005035718 89.0295 83.3333 ENSG00000063244 homo_sapiens ENSP00000307863 92.2105 86.7368 oncorhynchus_kisutch ENSOKIP00005040378 91.25 85.8333 ENSG00000063244 homo_sapiens ENSP00000307863 87.3684 81.4737 oncorhynchus_kisutch ENSOKIP00005094127 88.2979 82.3404 ENSG00000063244 homo_sapiens ENSP00000307863 92.2105 86.7368 oncorhynchus_kisutch ENSOKIP00005019384 91.25 85.8333 ENSG00000063244 homo_sapiens ENSP00000307863 92.2105 86.7368 oncorhynchus_mykiss ENSOMYP00000122970 91.25 85.8333 ENSG00000063244 homo_sapiens ENSP00000307863 88.6316 83.1579 oncorhynchus_mykiss ENSOMYP00000048566 88.8186 83.3333 ENSG00000063244 homo_sapiens ENSP00000307863 92.2105 86.7368 oncorhynchus_mykiss ENSOMYP00000005292 91.25 85.8333 ENSG00000063244 homo_sapiens ENSP00000307863 27.3684 25.6842 oncorhynchus_mykiss ENSOMYP00000132953 88.4354 82.9932 ENSG00000063244 homo_sapiens ENSP00000307863 88.2105 82.3158 salmo_salar ENSSSAP00000146739 88.7712 82.839 ENSG00000063244 homo_sapiens ENSP00000307863 92.2105 86.7368 salmo_salar ENSSSAP00000147937 87.4251 82.2355 ENSG00000063244 homo_sapiens ENSP00000307863 92.2105 86.7368 salmo_salar ENSSSAP00000177662 87.4251 82.2355 ENSG00000063244 homo_sapiens ENSP00000307863 88.8421 83.3684 salmo_salar ENSSSAP00000057707 89.0295 83.5443 ENSG00000063244 homo_sapiens ENSP00000307863 92.2105 86.7368 salmo_trutta ENSSTUP00000000624 91.25 85.8333 ENSG00000063244 homo_sapiens ENSP00000307863 88.8421 83.1579 salmo_trutta ENSSTUP00000067855 89.0295 83.3333 ENSG00000063244 homo_sapiens ENSP00000307863 88 82.1053 salmo_trutta ENSSTUP00000115053 88.5593 82.6271 ENSG00000063244 homo_sapiens ENSP00000307863 92.2105 86.7368 salmo_trutta ENSSTUP00000037948 91.25 85.8333 ENSG00000063244 homo_sapiens ENSP00000307863 92.2105 88 gadus_morhua ENSGMOP00000004812 95.0108 90.6725 ENSG00000063244 homo_sapiens ENSP00000307863 92.8421 88.2105 fundulus_heteroclitus ENSFHEP00000014425 89.8167 85.3361 ENSG00000063244 homo_sapiens ENSP00000307863 92.8421 88.2105 poecilia_reticulata ENSPREP00000012894 93.8298 89.1489 ENSG00000063244 homo_sapiens ENSP00000307863 92.8421 88.2105 xiphophorus_maculatus ENSXMAP00000012003 93.8298 89.1489 ENSG00000063244 homo_sapiens ENSP00000307863 92 87.1579 oryzias_latipes ENSORLP00000014464 92.9787 88.0851 ENSG00000063244 homo_sapiens ENSP00000307863 92.4211 88.2105 cyclopterus_lumpus ENSCLMP00005045883 91.841 87.6569 ENSG00000063244 homo_sapiens ENSP00000307863 92.4211 88.6316 oreochromis_niloticus ENSONIP00000016104 90.3292 86.6255 ENSG00000063244 homo_sapiens ENSP00000307863 92.8421 88.6316 haplochromis_burtoni ENSHBUP00000012196 93.8298 89.5745 ENSG00000063244 homo_sapiens ENSP00000307863 92.8421 88.6316 astatotilapia_calliptera ENSACLP00000032751 93.8298 89.5745 ENSG00000063244 homo_sapiens ENSP00000307863 92.6316 88.2105 sparus_aurata ENSSAUP00010058160 92.2432 87.8407 ENSG00000063244 homo_sapiens ENSP00000307863 93.2632 88.4211 lates_calcarifer ENSLCAP00010021122 92.2917 87.5 ENSG00000063244 homo_sapiens ENSP00000307863 94.9474 94.3158 xenopus_tropicalis ENSXETP00000041471 98.9035 98.2456 ENSG00000063244 homo_sapiens ENSP00000307863 91.7895 90.7368 chrysemys_picta_bellii ENSCPBP00000005626 97.9775 96.8539 ENSG00000063244 homo_sapiens ENSP00000307863 96.4211 95.7895 sphenodon_punctatus ENSSPUP00000013310 96.6245 95.9916 ENSG00000063244 homo_sapiens ENSP00000307863 96.6316 96 laticauda_laticaudata ENSLLTP00000024057 98.4979 97.8541 ENSG00000063244 homo_sapiens ENSP00000307863 93.8947 92.2105 notechis_scutatus ENSNSUP00000000931 93.8947 92.2105 ENSG00000063244 homo_sapiens ENSP00000307863 63.5789 59.3684 notechis_scutatus ENSNSUP00000006751 83.6565 78.1163 ENSG00000063244 homo_sapiens ENSP00000307863 65.2632 62.9474 pseudonaja_textilis ENSPTXP00000023569 91.9881 88.724 ENSG00000063244 homo_sapiens ENSP00000307863 96.6316 96 pseudonaja_textilis ENSPTXP00000021199 98.4979 97.8541 ENSG00000063244 homo_sapiens ENSP00000307863 24.8421 24 parus_major ENSPMJP00000005442 30.7292 29.6875 ENSG00000063244 homo_sapiens ENSP00000307863 17.4737 16.6316 parus_major ENSPMJP00000005327 24.1279 22.9651 ENSG00000063244 homo_sapiens ENSP00000307863 96.6316 96.2105 anolis_carolinensis ENSACAP00000015257 98.4979 98.0687 ENSG00000063244 homo_sapiens ENSP00000307863 92.8421 88.6316 neolamprologus_brichardi ENSNBRP00000003216 93.8298 89.5745 ENSG00000063244 homo_sapiens ENSP00000307863 94.3158 93.8947 naja_naja ENSNNAP00000010898 99.7773 99.3318 ENSG00000063244 homo_sapiens ENSP00000307863 96.6316 96.2105 podarcis_muralis ENSPMRP00000020625 98.4979 98.0687 ENSG00000063244 homo_sapiens ENSP00000307863 61.8947 57.8947 taeniopygia_guttata ENSTGUP00000024103 61.5063 57.5314 ENSG00000063244 homo_sapiens ENSP00000307863 93.8947 90.1053 erpetoichthys_calabaricus ENSECRP00000027677 96.3283 92.4406 ENSG00000063244 homo_sapiens ENSP00000307863 92.4211 88 kryptolebias_marmoratus ENSKMAP00000007951 93.4043 88.9362 ENSG00000063244 homo_sapiens ENSP00000307863 96.6316 96.2105 salvator_merianae ENSSMRP00000002951 98.4979 98.0687 ENSG00000063244 homo_sapiens ENSP00000307863 92 87.5789 oryzias_javanicus ENSOJAP00000021314 91.4226 87.0293 ENSG00000063244 homo_sapiens ENSP00000307863 86.7368 83.5789 amphilophus_citrinellus ENSACIP00000007340 95.814 92.3256 ENSG00000063244 homo_sapiens ENSP00000307863 82.9474 79.5789 amphiprion_percula ENSAPEP00000013190 92.7059 88.9412 ENSG00000063244 homo_sapiens ENSP00000307863 92 87.1579 oryzias_sinensis ENSOSIP00000006466 85.8546 81.336 ENSG00000063244 homo_sapiens ENSP00000307863 80 74.9474 pelodiscus_sinensis ENSPSIP00000008911 82.0734 76.8898 ENSG00000063244 homo_sapiens ENSP00000307863 96.4211 95.5789 gopherus_evgoodei ENSGEVP00005026339 94.824 93.9959 ENSG00000063244 homo_sapiens ENSP00000307863 82.1053 79.1579 chelonoidis_abingdonii ENSCABP00000014515 87.8378 84.6847 ENSG00000063244 homo_sapiens ENSP00000307863 92.6316 88 seriola_dumerili ENSSDUP00000013043 93.8166 89.1258 ENSG00000063244 homo_sapiens ENSP00000307863 92 88.2105 cottoperca_gobio ENSCGOP00000031626 91.6143 87.8407 ENSG00000063244 homo_sapiens ENSP00000307863 92 88.2105 gasterosteus_aculeatus ENSGACP00000014064 95.207 91.2854 ENSG00000063244 homo_sapiens ENSP00000307863 69.2632 65.6842 cynoglossus_semilaevis ENSCSEP00000029213 84.7938 80.4124 ENSG00000063244 homo_sapiens ENSP00000307863 92.6316 88 poecilia_formosa ENSPFOP00000010826 93.8166 89.1258 ENSG00000063244 homo_sapiens ENSP00000307863 92.4211 88.6316 myripristis_murdjan ENSMMDP00005024436 95.4348 91.5217 ENSG00000063244 homo_sapiens ENSP00000307863 92.6316 88.2105 sander_lucioperca ENSSLUP00000038448 92.2432 87.8407 ENSG00000063244 homo_sapiens ENSP00000307863 96.2105 94.9474 strigops_habroptila ENSSHBP00005007208 98.0687 96.7811 ENSG00000063244 homo_sapiens ENSP00000307863 92.6316 88.2105 amphiprion_ocellaris ENSAOCP00000011292 93.8166 89.339 ENSG00000063244 homo_sapiens ENSP00000307863 88 86.7368 terrapene_carolina_triunguis ENSTMTP00000026462 93.9326 92.5843 ENSG00000063244 homo_sapiens ENSP00000307863 92.2105 86.7368 hucho_hucho ENSHHUP00000029377 87.4251 82.2355 ENSG00000063244 homo_sapiens ENSP00000307863 18.9474 16 hucho_hucho ENSHHUP00000043920 73.1707 61.7886 ENSG00000063244 homo_sapiens ENSP00000307863 49.8947 46.3158 hucho_hucho ENSHHUP00000066217 85.8696 79.7101 ENSG00000063244 homo_sapiens ENSP00000307863 92.2105 86.7368 hucho_hucho ENSHHUP00000040561 87.4251 82.2355 ENSG00000063244 homo_sapiens ENSP00000307863 92.6316 88.4211 betta_splendens ENSBSLP00000029153 89.7959 85.7143 ENSG00000063244 homo_sapiens ENSP00000307863 91.3684 87.5789 pygocentrus_nattereri ENSPNAP00000011907 93.7365 89.8488 ENSG00000063244 homo_sapiens ENSP00000307863 91.3684 86.9474 pygocentrus_nattereri ENSPNAP00000020414 93.7365 89.2009 ENSG00000063244 homo_sapiens ENSP00000307863 92.6316 88.2105 anabas_testudineus ENSATEP00000032428 93.617 89.1489 ENSG00000063244 homo_sapiens ENSP00000307863 74.9474 63.5789 ciona_savignyi ENSCSAVP00000011610 74.6331 63.3124 ENSG00000063244 homo_sapiens ENSP00000307863 92.8421 88.2105 seriola_lalandi_dorsalis ENSSLDP00000029484 93.8298 89.1489 ENSG00000063244 homo_sapiens ENSP00000307863 92.6316 88 labrus_bergylta ENSLBEP00000021053 93.617 88.9362 ENSG00000063244 homo_sapiens ENSP00000307863 92.8421 88.6316 pundamilia_nyererei ENSPNYP00000001823 93.8298 89.5745 ENSG00000063244 homo_sapiens ENSP00000307863 92.8421 87.7895 mastacembelus_armatus ENSMAMP00000029461 92.6471 87.605 ENSG00000063244 homo_sapiens ENSP00000307863 92.8421 88.4211 stegastes_partitus ENSSPAP00000029951 93.8298 89.3617 ENSG00000063244 homo_sapiens ENSP00000307863 88.6316 83.1579 oncorhynchus_tshawytscha ENSOTSP00005044303 88.8186 83.3333 ENSG00000063244 homo_sapiens ENSP00000307863 88.6316 83.1579 oncorhynchus_tshawytscha ENSOTSP00005077930 88.8186 83.3333 ENSG00000063244 homo_sapiens ENSP00000307863 92.2105 86.7368 oncorhynchus_tshawytscha ENSOTSP00005085567 91.25 85.8333 ENSG00000063244 homo_sapiens ENSP00000307863 62.5263 60.6316 acanthochromis_polyacanthus ENSAPOP00000019664 91.9505 89.1641 ENSG00000063244 homo_sapiens ENSP00000307863 54.1053 51.1579 nothobranchius_furzeri ENSNFUP00015042867 91.4591 86.4769 ENSG00000063244 homo_sapiens ENSP00000307863 93.0526 87.5789 nothobranchius_furzeri ENSNFUP00015018982 92.8571 87.395 ENSG00000063244 homo_sapiens ENSP00000307863 92.8421 88.2105 cyprinodon_variegatus ENSCVAP00000020100 93.8298 89.1489 ENSG00000063244 homo_sapiens ENSP00000307863 90.9474 85.4737 denticeps_clupeoides ENSDCDP00000022707 92.5054 86.9379 ENSG00000063244 homo_sapiens ENSP00000307863 93.2632 88 denticeps_clupeoides ENSDCDP00000037843 93.0672 87.8151 ENSG00000063244 homo_sapiens ENSP00000307863 92.4211 88 larimichthys_crocea ENSLCRP00005025329 89.959 85.6557 ENSG00000063244 homo_sapiens ENSP00000307863 86.7368 81.4737 takifugu_rubripes ENSTRUP00000068126 80.1556 75.2918 ENSG00000063244 homo_sapiens ENSP00000307863 92.6316 87.7895 hippocampus_comes ENSHCOP00000015686 92.2432 87.4214 ENSG00000063244 homo_sapiens ENSP00000307863 91.3684 86.9474 cyprinus_carpio_carpio ENSCCRP00000110606 92.9336 88.4368 ENSG00000063244 homo_sapiens ENSP00000307863 92 85.8947 cyprinus_carpio_carpio ENSCCRP00000070359 89.9177 83.9506 ENSG00000063244 homo_sapiens ENSP00000307863 91.3684 87.3684 cyprinus_carpio_carpio ENSCCRP00000043247 91.5612 87.5527 ENSG00000063244 homo_sapiens ENSP00000307863 92.4211 85.8947 cyprinus_carpio_carpio ENSCCRP00000144809 90.5155 84.1237 ENSG00000063244 homo_sapiens ENSP00000307863 92.8421 88.2105 poecilia_latipinna ENSPLAP00000026494 93.8298 89.1489 ENSG00000063244 homo_sapiens ENSP00000307863 91.7895 85.6842 sinocyclocheilus_grahami ENSSGRP00000109516 91.5966 85.5042 ENSG00000063244 homo_sapiens ENSP00000307863 75.7895 68 sinocyclocheilus_grahami ENSSGRP00000061846 82.3799 73.913 ENSG00000063244 homo_sapiens ENSP00000307863 56.2105 51.7895 sinocyclocheilus_grahami ENSSGRP00000019552 87.8289 80.9211 ENSG00000063244 homo_sapiens ENSP00000307863 91.3684 86.9474 sinocyclocheilus_grahami ENSSGRP00000046075 90.0415 85.6846 ENSG00000063244 homo_sapiens ENSP00000307863 92.8421 88.6316 maylandia_zebra ENSMZEP00005022089 93.8298 89.5745 ENSG00000063244 homo_sapiens ENSP00000307863 92 88 tetraodon_nigroviridis ENSTNIP00000010931 93.177 89.1258 ENSG00000063244 homo_sapiens ENSP00000307863 92.8421 88.8421 paramormyrops_kingsleyae ENSPKIP00000009133 78.75 75.3571 ENSG00000063244 homo_sapiens ENSP00000307863 92 88 scleropages_formosus ENSSFOP00015045780 91.2317 87.2651 ENSG00000063244 homo_sapiens ENSP00000307863 69.0526 65.4737 leptobrachium_leishanense ENSLLEP00000005053 87.234 82.7128 ENSG00000063244 homo_sapiens ENSP00000307863 69.4737 65.8947 leptobrachium_leishanense ENSLLEP00000040429 84.6154 80.2564 ENSG00000063244 homo_sapiens ENSP00000307863 69.0526 65.4737 leptobrachium_leishanense ENSLLEP00000036683 84.1026 79.7436 ENSG00000063244 homo_sapiens ENSP00000307863 95.3684 94.1053 leptobrachium_leishanense ENSLLEP00000014206 97.4194 96.129 ENSG00000063244 homo_sapiens ENSP00000307863 81.4737 78.3158 scophthalmus_maximus ENSSMAP00000020585 94.621 90.9535 ENSG00000063244 homo_sapiens ENSP00000307863 92.2105 87.7895 oryzias_melastigma ENSOMEP00000028338 93.3902 88.9126
Go ID
Go term
No. evidence
Entries
Species
Category
GO:0000243 part_of commitment complex 1 IBA Homo_sapiens(9606) Component GO:0000398 involved_in mRNA splicing, via spliceosome 3 IC,IDA,NAS Homo_sapiens(9606) Process GO:0003723 enables RNA binding 1 HDA Homo_sapiens(9606) Function GO:0005515 enables protein binding 1 IPI Homo_sapiens(9606) Function GO:0005634 located_in nucleus 2 IDA,NAS Homo_sapiens(9606) Component GO:0005654 located_in nucleoplasm 1 TAS Homo_sapiens(9606) Component GO:0005681 part_of spliceosomal complex 2 IDA,IPI Homo_sapiens(9606) Component GO:0006397 involved_in mRNA processing 1 TAS Homo_sapiens(9606) Process GO:0008187 enables poly-pyrimidine tract binding 1 IBA Homo_sapiens(9606) Function GO:0016607 is_active_in nuclear speck 2 IBA,IDA Homo_sapiens(9606) Component GO:0019899 enables enzyme binding 1 IPI Homo_sapiens(9606) Function GO:0030628 enables pre-mRNA 3-splice site binding 2 IBA,IDA Homo_sapiens(9606) Function GO:0031397 involved_in negative regulation of protein ubiquitination 2 IDA,IMP Homo_sapiens(9606) Process GO:0033120 involved_in positive regulation of RNA splicing 1 IDA Homo_sapiens(9606) Process GO:0048025 involved_in negative regulation of mRNA splicing, via spliceosome 1 IDA Homo_sapiens(9606) Process GO:0070742 enables C2H2 zinc finger domain binding 1 IEA Homo_sapiens(9606) Function GO:0071004 part_of U2-type prespliceosome 2 IBA,IDA Homo_sapiens(9606) Component GO:0089701 part_of U2AF complex 3 IBA,IDA,IPI Homo_sapiens(9606) Component GO:0140678 enables molecular function inhibitor activity 1 EXP Homo_sapiens(9606) Function
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