RBP Type
Canonical_RBPs
Diseases
CancerFlaviviruses SARS-COV-2 SINV Dengue Zika
Drug
N.A.
Main interacting RNAs
mRNA
Moonlighting functions
N.A.
Localizations
Stress granucle P-body
BulkPerturb-seq
DataSet_01_16
Ensembl ID ENSG00000047188 Gene ID
64848
Accession
24721
Symbol
YTHDC2
Alias
CAHL;hYTHDC2
Full Name
YTH N6-methyladenosine RNA binding protein C2
Status
Confidence
Length
81591 bases
Strand
Plus strand
Position
5 : 113513694 - 113595284
RNA binding domain
DEAD , R3H , HA2 , YTH , OB_NTP_bind
Summary
This gene encodes a member of the DEAH (Asp-Glu-Ala-His) subfamily of proteins, part of the DEAD (Asp-Glu-Ala-Asp) box family of RNA helicases. The encoded protein binds to N6-methyladenosine, a common modified RNA nucleotide that is enriched in the stop codons and 3' UTRs of eukaryotic messenger RNAs. Binding of proteins to this modified nucleotide may regulate mRNA translation and stability. This gene may be associated with susceptibility to pancreatic cancer in human patients, and knockdown of this gene resulted in reduced proliferation in a human liver cancer cell line. [provided by RefSeq, Sep 2016]
RNA binding domains (RBDs)
Protein
Domain
Pfam ID
E-value
Domain number
ENSP00000423101
R3H
PF01424
1.5e-10
1
ENSP00000423101
DEAD
PF00270
1.5e-09
2
ENSP00000161863
R3H
PF01424
3.8e-10
1
ENSP00000161863
DEAD
PF00270
5.1e-09
2
ENSP00000161863
YTH
PF04146
1.1e-41
3
ENSP00000161863
YTH
PF04146
1.1e-41
4
ENSP00000161863
HA2
PF04408
1.7e-17
5
ENSP00000161863
OB_NTP_bind
PF07717
7.9e-11
6
ENSP00000422916
R3H
PF01424
5.8e-10
1
ENSP00000426644
R3H
PF01424
2.6e-07
1
RNA binding proteomes (RBPomes)
Pubmed ID
Full Name
Cell
Author
Time
Doi
Literatures on RNA binding capacity
Pubmed ID
Title
Author
Time
Journal
36747642
YTHDC2 serves a distinct late role in spermatocytes during germ cell differentiation.
S Alexis Bailey
2023-01-23
bioRxiv : the preprint server for biology
32956555
Downregulation of m6 A reader YTHDC2 promotes tumor progression and predicts poor prognosis in non-small cell lung cancer.
Shulei Sun
2020-11-01
Thoracic cancer
32961012
m6A RNA methylation regulators could contribute to the occurrence of chronic obstructive pulmonary disease.
Xinwei Huang
2020-11-01
Journal of cellular and molecular medicine
37152066
m6A modification on the fate of colorectal cancer: functions and mechanisms of cell proliferation and tumorigenesis.
Xiaohan Jiang
2023-01-01
Frontiers in oncology
32850334
m6 A Reader YTHDC2 Promotes Radiotherapy Resistance of Nasopharyngeal Carcinoma via Activating IGF1R/AKT/S6 Signaling Axis.
Jun-Ju He
2020-01-01
Frontiers in oncology
37636387
YTHDC2 inhibits rat bone mesenchymal stem cells osteogenic differentiation by accelerating RUNX2 mRNA degradation via m6A methylation.
Bo Ma
2023-08-01
Heliyon
36001654
RNA binding protein RBM46 regulates mitotic-to-meiotic transition in spermatogenesis.
Baomei Qian
2022-08-26
Science advances
29789545
Dynamic transcriptomic m6 A decoration: writers, erasers, readers and functions in RNA metabolism.
Ying Yang
2018-06-01
Cell research
30891023
N6 -Methyladenosine and Viral Infection.
Wei Dang
2019-01-01
Frontiers in microbiology
Name
Transcript ID
bp
Protein
Translation ID
YTHDC2-202
ENST00000503857
2138
98aa
ENSP00000426644
YTHDC2-201
ENST00000161863
6305
1430aa
ENSP00000161863
YTHDC2-207
ENST00000515883
2629
739aa
ENSP00000423101
YTHDC2-206
ENST00000514720
536
137aa
ENSP00000422916
YTHDC2-203
ENST00000506333
784
No protein
-
YTHDC2-205
ENST00000512600
6708
No protein
-
YTHDC2-204
ENST00000507567
693
No protein
-
Pathway ID
Pathway Name
Source
ensgID
Trait
pValue
Pubmed ID
1106 Body Weights and Measures 4.18538902584586E-5 17903300 1288 Body Weights and Measures 4.38873780244098E-5 17903300 2568 Body Weights and Measures 7.37042521352649E-5 17903300 2683 Body Weights and Measures 6.92057409599212E-5 17903300 3992 Triglycerides 8.45932720099363E-5 17903299 22985 Body Height 6.8990000E-005 - 23004 Body Height 7.2200000E-005 - 23164 Body Height 7.4960000E-005 - 23166 Body Height 8.7310000E-005 - 29795 Lipoprotein(a) 8.9560000E-005 - 31347 Erythrocyte Indices 1.3110000E-005 - 31495 Erythrocyte Count 2.0630000E-006 - 36319 Platelet Function Tests 9.6900000E-006 - 36326 Platelet Function Tests 3.0200000E-006 - 36571 Platelet Function Tests 2.2702400E-005 - 39608 Platelet Function Tests 2.0620800E-005 - 47047 Platelet Function Tests 2.6103000E-005 - 47049 Platelet Function Tests 4.2897000E-005 - 47765 Language Tests 2.3133000E-005 - 47782 Language Tests 3.8634000E-005 - 55250 Erythrocyte Indices 4.4560000E-005 - 59392 Arterial Pressure 2.8110000E-006 - 59400 Arterial Pressure 5.8670000E-006 - 73085 Death, Sudden, Cardiac 4E-8 21658281 90060 Anemia, Sickle Cell 8E-6 21326311 90061 Fetal Hemoglobin 8E-6 21326311 102858 Sleep 7E-6 27126917 105815 Alzheimer Disease 9E-7 26830138 105816 Age of Onset 9E-7 26830138
ensgID SNP Chromosome Position
Trait PubmedID Or or BEAT
EFO ID
Protein-Protein Interaction (PPI)
Ensembl ID
Source
Target
Species
Protein ID
Perc_pos
Perc_id
Species
Protein ID
Perc_pos
Perc_id
ENSG00000047188 homo_sapiens ENSP00000268482 32.1923 19.0709 homo_sapiens ENSP00000161863 27.6224 16.3636 ENSG00000047188 homo_sapiens ENSP00000251636 36.2308 23.74 homo_sapiens ENSP00000161863 34.6853 22.7273 ENSG00000047188 homo_sapiens ENSP00000331907 38.7577 24.0595 homo_sapiens ENSP00000161863 30.979 19.2308 ENSG00000047188 homo_sapiens ENSP00000356520 36.6142 24.9606 homo_sapiens ENSP00000161863 32.5175 22.1678 ENSG00000047188 homo_sapiens ENSP00000284690 44.9529 24.2261 homo_sapiens ENSP00000161863 23.3566 12.5874 ENSG00000047188 homo_sapiens ENSP00000225296 46.1103 26.7327 homo_sapiens ENSP00000161863 22.7972 13.2168 ENSG00000047188 homo_sapiens ENSP00000247815 25.023 12.5115 homo_sapiens ENSP00000161863 19.021 9.51049 ENSG00000047188 homo_sapiens ENSP00000384621 44.6304 25.2441 homo_sapiens ENSP00000161863 22.3776 12.6573 ENSG00000047188 homo_sapiens ENSP00000252011 50.3556 30.1565 homo_sapiens ENSP00000161863 24.7552 14.8252 ENSG00000047188 homo_sapiens ENSP00000311135 34.745 20.8297 homo_sapiens ENSP00000161863 28.1119 16.8531 ENSG00000047188 homo_sapiens ENSP00000405111 36.7244 23.8095 homo_sapiens ENSP00000161863 35.5944 23.0769 ENSG00000047188 homo_sapiens ENSP00000365625 36.3112 22.3823 homo_sapiens ENSP00000161863 26.4336 16.2937 ENSG00000047188 homo_sapiens ENSP00000417078 47.3214 31.0516 homo_sapiens ENSP00000161863 33.3566 21.8881 ENSG00000047188 homo_sapiens ENSP00000251241 47.3684 25.6739 homo_sapiens ENSP00000161863 25.8042 13.986 ENSG00000047188 homo_sapiens ENSP00000336741 47.1698 29.434 homo_sapiens ENSP00000161863 26.2238 16.3636 ENSG00000047188 homo_sapiens ENSP00000405620 38.1072 23.6181 homo_sapiens ENSP00000161863 31.8182 19.7203 ENSG00000047188 homo_sapiens ENSP00000262415 33.0328 18.8525 homo_sapiens ENSP00000161863 28.1818 16.0839 ENSG00000047188 homo_sapiens ENSP00000387303 31.6208 18.4515 homo_sapiens ENSP00000161863 30.5594 17.8322
Ensembl ID
Source
Target
Species
Protein ID
Perc_pos
Perc_id
Species
Protein ID
Perc_pos
Perc_id
ENSG00000047188 homo_sapiens ENSP00000161863 99.4406 98.6713 nomascus_leucogenys ENSNLEP00000014221 99.4406 98.6713 ENSG00000047188 homo_sapiens ENSP00000161863 99.8601 99.6504 pan_paniscus ENSPPAP00000004480 99.8601 99.6504 ENSG00000047188 homo_sapiens ENSP00000161863 98.7413 97.9021 pongo_abelii ENSPPYP00000038311 98.1237 97.2898 ENSG00000047188 homo_sapiens ENSP00000161863 99.7902 99.5804 pan_troglodytes ENSPTRP00000029337 99.7902 99.5804 ENSG00000047188 homo_sapiens ENSP00000161863 99.7203 99.4406 gorilla_gorilla ENSGGOP00000019640 99.7203 99.4406 ENSG00000047188 homo_sapiens ENSP00000161863 84.4755 72.0979 ornithorhynchus_anatinus ENSOANP00000044317 78.4925 66.9916 ENSG00000047188 homo_sapiens ENSP00000161863 98.6014 96.4336 sarcophilus_harrisii ENSSHAP00000003531 97.9847 95.8304 ENSG00000047188 homo_sapiens ENSP00000161863 73.5664 71.4685 notamacropus_eugenii ENSMEUP00000004041 73.5664 71.4685 ENSG00000047188 homo_sapiens ENSP00000161863 76.4336 74.7552 choloepus_hoffmanni ENSCHOP00000011820 80.3086 78.5452 ENSG00000047188 homo_sapiens ENSP00000161863 97.2028 94.5455 dasypus_novemcinctus ENSDNOP00000009488 97.1349 94.4794 ENSG00000047188 homo_sapiens ENSP00000161863 82.3776 80.2098 erinaceus_europaeus ENSEEUP00000007886 83.4869 81.2899 ENSG00000047188 homo_sapiens ENSP00000161863 74.0559 72.3077 echinops_telfairi ENSETEP00000011097 75.1597 73.3854 ENSG00000047188 homo_sapiens ENSP00000161863 99.021 97.8322 callithrix_jacchus ENSCJAP00000083161 99.021 97.8322 ENSG00000047188 homo_sapiens ENSP00000161863 99.7902 99.2308 cercocebus_atys ENSCATP00000015397 99.7902 99.2308 ENSG00000047188 homo_sapiens ENSP00000161863 95.3846 94.8951 macaca_fascicularis ENSMFAP00000058611 99.7805 99.2685 ENSG00000047188 homo_sapiens ENSP00000161863 99.7902 99.2308 macaca_mulatta ENSMMUP00000001834 99.7902 99.2308 ENSG00000047188 homo_sapiens ENSP00000161863 99.7902 99.3007 macaca_nemestrina ENSMNEP00000035513 99.7902 99.3007 ENSG00000047188 homo_sapiens ENSP00000161863 99.7203 99.0909 papio_anubis ENSPANP00000049610 99.7203 99.0909 ENSG00000047188 homo_sapiens ENSP00000161863 99.7203 99.3007 mandrillus_leucophaeus ENSMLEP00000038248 99.7203 99.3007 ENSG00000047188 homo_sapiens ENSP00000161863 73.0769 71.049 tursiops_truncatus ENSTTRP00000002924 74.8031 72.7273 ENSG00000047188 homo_sapiens ENSP00000161863 98.951 97.2727 vulpes_vulpes ENSVVUP00000000289 99.0203 97.3408 ENSG00000047188 homo_sapiens ENSP00000161863 98.6713 96.993 mus_spretus MGP_SPRETEiJ_P0048591 97.8502 96.1859 ENSG00000047188 homo_sapiens ENSP00000161863 98.8112 97.5524 equus_asinus ENSEASP00005022153 98.5356 97.2803 ENSG00000047188 homo_sapiens ENSP00000161863 98.3916 96.7832 capra_hircus ENSCHIP00000032847 98.4605 96.8509 ENSG00000047188 homo_sapiens ENSP00000161863 87.9021 86.6434 loxodonta_africana ENSLAFP00000002949 98.6656 97.2527 ENSG00000047188 homo_sapiens ENSP00000161863 98.6014 97.0629 panthera_leo ENSPLOP00000001027 98.7395 97.1989 ENSG00000047188 homo_sapiens ENSP00000161863 98.5315 96.9231 ailuropoda_melanoleuca ENSAMEP00000006972 98.6004 96.9909 ENSG00000047188 homo_sapiens ENSP00000161863 96.3636 94.4755 bos_indicus_hybrid ENSBIXP00005038323 96.974 95.0739 ENSG00000047188 homo_sapiens ENSP00000161863 94.4056 92.9371 oryctolagus_cuniculus ENSOCUP00000010414 98.7564 97.2202 ENSG00000047188 homo_sapiens ENSP00000161863 96.9231 95.6643 equus_caballus ENSECAP00000018278 98.5075 97.2281 ENSG00000047188 homo_sapiens ENSP00000161863 98.951 97.3427 canis_lupus_familiaris ENSCAFP00845014394 99.0203 97.4108 ENSG00000047188 homo_sapiens ENSP00000161863 98.5315 97.1329 panthera_pardus ENSPPRP00000006048 98.6695 97.2689 ENSG00000047188 homo_sapiens ENSP00000161863 97.972 96.6434 marmota_marmota_marmota ENSMMMP00000007376 98.3848 97.0506 ENSG00000047188 homo_sapiens ENSP00000161863 98.3217 96.2937 balaenoptera_musculus ENSBMSP00010017470 98.3217 96.2937 ENSG00000047188 homo_sapiens ENSP00000161863 98.3916 96.7832 cavia_porcellus ENSCPOP00000023264 97.8442 96.2448 ENSG00000047188 homo_sapiens ENSP00000161863 98.6014 97.1329 felis_catus ENSFCAP00000018534 98.7395 97.2689 ENSG00000047188 homo_sapiens ENSP00000161863 75.2448 74.3357 ursus_americanus ENSUAMP00000004139 98.8971 97.7022 ENSG00000047188 homo_sapiens ENSP00000161863 98.5315 96.3636 monodelphis_domestica ENSMODP00000019558 97.3739 95.2315 ENSG00000047188 homo_sapiens ENSP00000161863 98.3916 96.7832 bison_bison_bison ENSBBBP00000001471 98.4605 96.8509 ENSG00000047188 homo_sapiens ENSP00000161863 97.6923 94.965 monodon_monoceros ENSMMNP00015001288 97.7607 95.0315 ENSG00000047188 homo_sapiens ENSP00000161863 98.6713 97.4126 sus_scrofa ENSSSCP00000048904 98.8788 97.6174 ENSG00000047188 homo_sapiens ENSP00000161863 99.1608 97.8322 microcebus_murinus ENSMICP00000025265 98.6778 97.3556 ENSG00000047188 homo_sapiens ENSP00000161863 98.2517 96.1538 octodon_degus ENSODEP00000010452 98.0461 95.9525 ENSG00000047188 homo_sapiens ENSP00000161863 95.5245 93.2168 jaculus_jaculus ENSJJAP00000015913 95.5913 93.282 ENSG00000047188 homo_sapiens ENSP00000161863 98.3916 96.7832 ovis_aries_rambouillet ENSOARP00020021748 98.4605 96.8509 ENSG00000047188 homo_sapiens ENSP00000161863 95.1748 93.7063 ursus_maritimus ENSUMAP00000033151 98.9099 97.3837 ENSG00000047188 homo_sapiens ENSP00000161863 73.007 71.6084 ochotona_princeps ENSOPRP00000000434 73.2632 71.8596 ENSG00000047188 homo_sapiens ENSP00000161863 97.6923 94.965 delphinapterus_leucas ENSDLEP00000027795 97.7607 95.0315 ENSG00000047188 homo_sapiens ENSP00000161863 98.042 95.9441 physeter_catodon ENSPCTP00005000946 98.042 95.9441 ENSG00000047188 homo_sapiens ENSP00000161863 98.6713 96.993 mus_caroli MGP_CAROLIEiJ_P0046663 97.6471 95.9862 ENSG00000047188 homo_sapiens ENSP00000161863 98.7413 96.993 mus_musculus ENSMUSP00000048340 97.7163 95.9862 ENSG00000047188 homo_sapiens ENSP00000161863 92.4476 90 dipodomys_ordii ENSDORP00000006616 94.9031 92.3905 ENSG00000047188 homo_sapiens ENSP00000161863 94.8951 93.0769 mustela_putorius_furo ENSMPUP00000000752 97.9783 96.1011 ENSG00000047188 homo_sapiens ENSP00000161863 96.5035 95.2448 aotus_nancymaae ENSANAP00000008452 98.1508 96.8706 ENSG00000047188 homo_sapiens ENSP00000161863 99.3706 98.5315 saimiri_boliviensis_boliviensis ENSSBOP00000014179 99.3706 98.5315 ENSG00000047188 homo_sapiens ENSP00000161863 89.7203 87.3427 vicugna_pacos ENSVPAP00000006992 90.4158 88.0197 ENSG00000047188 homo_sapiens ENSP00000161863 99.5804 99.1608 chlorocebus_sabaeus ENSCSAP00000011006 99.5804 99.1608 ENSG00000047188 homo_sapiens ENSP00000161863 70.979 69.3007 tupaia_belangeri ENSTBEP00000005973 74.4135 72.654 ENSG00000047188 homo_sapiens ENSP00000161863 98.6014 96.993 mesocricetus_auratus ENSMAUP00000017308 97.7131 96.1192 ENSG00000047188 homo_sapiens ENSP00000161863 97.7622 95.1748 phocoena_sinus ENSPSNP00000000778 97.8307 95.2414 ENSG00000047188 homo_sapiens ENSP00000161863 98.8112 97.2727 camelus_dromedarius ENSCDRP00005008846 98.8803 97.3408 ENSG00000047188 homo_sapiens ENSP00000161863 95.4545 94.1259 carlito_syrichta ENSTSYP00000008859 97.8495 96.4875 ENSG00000047188 homo_sapiens ENSP00000161863 94.4056 92.9371 panthera_tigris_altaica ENSPTIP00000026363 94.4056 92.9371 ENSG00000047188 homo_sapiens ENSP00000161863 98.6713 97.1329 rattus_norvegicus ENSRNOP00000078225 98.3961 96.8619 ENSG00000047188 homo_sapiens ENSP00000161863 99.021 97.6923 prolemur_simus ENSPSMP00000036785 98.8137 97.4878 ENSG00000047188 homo_sapiens ENSP00000161863 98.7413 97.0629 microtus_ochrogaster ENSMOCP00000011495 98.3972 96.7247 ENSG00000047188 homo_sapiens ENSP00000161863 79.3007 77.972 sorex_araneus ENSSARP00000000877 84.8802 83.4581 ENSG00000047188 homo_sapiens ENSP00000161863 98.7413 97.2028 peromyscus_maniculatus_bairdii ENSPEMP00000019960 97.2452 95.73 ENSG00000047188 homo_sapiens ENSP00000161863 98.3916 96.7832 bos_mutus ENSBMUP00000003464 98.4605 96.8509 ENSG00000047188 homo_sapiens ENSP00000161863 98.7413 96.9231 mus_spicilegus ENSMSIP00000028837 97.8517 96.0499 ENSG00000047188 homo_sapiens ENSP00000161863 98.6713 97.0629 cricetulus_griseus_chok1gshd ENSCGRP00001022960 98.4648 96.8597 ENSG00000047188 homo_sapiens ENSP00000161863 91.5385 90.0699 pteropus_vampyrus ENSPVAP00000011653 91.5385 90.0699 ENSG00000047188 homo_sapiens ENSP00000161863 98.1818 96.1538 myotis_lucifugus ENSMLUP00000005590 97.5678 95.5525 ENSG00000047188 homo_sapiens ENSP00000161863 94.3357 92.0979 vombatus_ursinus ENSVURP00010008273 98.6833 96.3424 ENSG00000047188 homo_sapiens ENSP00000161863 98.8112 97.3427 rhinolophus_ferrumequinum ENSRFEP00010021939 98.9496 97.479 ENSG00000047188 homo_sapiens ENSP00000161863 98.6014 96.9231 neovison_vison ENSNVIP00000029999 98.6704 96.9909 ENSG00000047188 homo_sapiens ENSP00000161863 98.3916 96.7832 bos_taurus ENSBTAP00000018745 98.4605 96.8509 ENSG00000047188 homo_sapiens ENSP00000161863 97.6224 95.6643 heterocephalus_glaber_female ENSHGLP00000026729 97.3501 95.3975 ENSG00000047188 homo_sapiens ENSP00000161863 97.6923 96.8531 rhinopithecus_bieti ENSRBIP00000033047 98.519 97.6728 ENSG00000047188 homo_sapiens ENSP00000161863 97.4126 95.8741 canis_lupus_dingo ENSCAFP00020004703 97.823 96.2781 ENSG00000047188 homo_sapiens ENSP00000161863 98.951 97.7622 sciurus_vulgaris ENSSVLP00005013094 98.6063 97.4216 ENSG00000047188 homo_sapiens ENSP00000161863 98.3217 95.7343 phascolarctos_cinereus ENSPCIP00000005224 98.6667 96.0702 ENSG00000047188 homo_sapiens ENSP00000161863 76.0839 74.4755 procavia_capensis ENSPCAP00000007363 76.9448 75.3182 ENSG00000047188 homo_sapiens ENSP00000161863 97.972 96.2937 nannospalax_galili ENSNGAP00000017329 98.178 96.4961 ENSG00000047188 homo_sapiens ENSP00000161863 98.3916 96.7832 bos_grunniens ENSBGRP00000019159 98.4605 96.8509 ENSG00000047188 homo_sapiens ENSP00000161863 98.3217 96.2937 chinchilla_lanigera ENSCLAP00000020554 97.4359 95.4262 ENSG00000047188 homo_sapiens ENSP00000161863 98.5315 96.7832 cervus_hanglu_yarkandensis ENSCHYP00000040774 98.6004 96.8509 ENSG00000047188 homo_sapiens ENSP00000161863 98.4615 96.7832 catagonus_wagneri ENSCWAP00000001439 98.6685 96.9867 ENSG00000047188 homo_sapiens ENSP00000161863 97.2727 95.8741 ictidomys_tridecemlineatus ENSSTOP00000011876 97.0691 95.6734 ENSG00000047188 homo_sapiens ENSP00000161863 99.0909 97.7622 otolemur_garnettii ENSOGAP00000001441 98.6769 97.3538 ENSG00000047188 homo_sapiens ENSP00000161863 99.4406 98.3916 cebus_imitator ENSCCAP00000039603 99.3711 98.3229 ENSG00000047188 homo_sapiens ENSP00000161863 98.6014 96.7832 moschus_moschiferus ENSMMSP00000007791 98.6704 96.8509 ENSG00000047188 homo_sapiens ENSP00000161863 99.7203 99.1608 rhinopithecus_roxellana ENSRROP00000031564 99.7203 99.1608 ENSG00000047188 homo_sapiens ENSP00000161863 98.7413 96.993 mus_pahari MGP_PahariEiJ_P0039252 97.7839 96.0526 ENSG00000047188 homo_sapiens ENSP00000161863 91.4685 88.6014 propithecus_coquereli ENSPCOP00000011981 96.8172 93.7824 ENSG00000047188 homo_sapiens ENSP00000161863 35.7343 21.5385 drosophila_melanogaster FBpp0308827 52.3566 31.5574 ENSG00000047188 homo_sapiens ENSP00000161863 16.014 11.958 ciona_intestinalis ENSCINP00000011574 65.8046 49.1379 ENSG00000047188 homo_sapiens ENSP00000161863 76.8531 61.7483 petromyzon_marinus ENSPMAP00000003531 77.7228 62.447 ENSG00000047188 homo_sapiens ENSP00000161863 62.6573 46.993 eptatretus_burgeri ENSEBUP00000023364 64.3678 48.2759 ENSG00000047188 homo_sapiens ENSP00000161863 24.6853 17.6923 eptatretus_burgeri ENSEBUP00000006318 62.9234 45.098 ENSG00000047188 homo_sapiens ENSP00000161863 89.8601 81.958 callorhinchus_milii ENSCMIP00000042142 90.3657 82.4191 ENSG00000047188 homo_sapiens ENSP00000161863 92.7972 85.6643 latimeria_chalumnae ENSLACP00000012473 92.8621 85.7243 ENSG00000047188 homo_sapiens ENSP00000161863 86.1538 76.1538 lepisosteus_oculatus ENSLOCP00000010962 86.335 76.3139 ENSG00000047188 homo_sapiens ENSP00000161863 75.9441 61.8881 danio_rerio ENSDARP00000132196 76.7491 62.5442 ENSG00000047188 homo_sapiens ENSP00000161863 82.6573 70 carassius_auratus ENSCARP00000054164 85.7765 72.6415 ENSG00000047188 homo_sapiens ENSP00000161863 85.1748 72.7273 astyanax_mexicanus ENSAMXP00000009255 85.8956 73.3427 ENSG00000047188 homo_sapiens ENSP00000161863 82.9371 71.7483 ictalurus_punctatus ENSIPUP00000029005 81.7931 70.7586 ENSG00000047188 homo_sapiens ENSP00000161863 86.5734 75.1748 esox_lucius ENSELUP00000036514 85.3205 74.0868 ENSG00000047188 homo_sapiens ENSP00000161863 82.1678 70.3496 electrophorus_electricus ENSEEEP00000036038 83.0389 71.0954 ENSG00000047188 homo_sapiens ENSP00000161863 86.7133 75.9441 oncorhynchus_kisutch ENSOKIP00005079379 85.1064 74.5367 ENSG00000047188 homo_sapiens ENSP00000161863 86.7832 76.1538 oncorhynchus_mykiss ENSOMYP00000090454 86.1208 75.5725 ENSG00000047188 homo_sapiens ENSP00000161863 36.8531 30.3496 salmo_salar ENSSSAP00000084980 75.3934 62.0887 ENSG00000047188 homo_sapiens ENSP00000161863 86.9231 76.2937 salmo_salar ENSSSAP00000149457 85.7241 75.2414 ENSG00000047188 homo_sapiens ENSP00000161863 86.9231 76.3636 salmo_trutta ENSSTUP00000050298 85.7241 75.3103 ENSG00000047188 homo_sapiens ENSP00000161863 37.4126 31.6084 salmo_trutta ENSSTUP00000008483 76.5379 64.6638 ENSG00000047188 homo_sapiens ENSP00000161863 57.8322 45.4545 gadus_morhua ENSGMOP00000046483 71.1092 55.8899 ENSG00000047188 homo_sapiens ENSP00000161863 75.1049 60.6993 fundulus_heteroclitus ENSFHEP00000026394 74.1713 59.9448 ENSG00000047188 homo_sapiens ENSP00000161863 75.8741 60.8392 poecilia_reticulata ENSPREP00000017945 76.5162 61.354 ENSG00000047188 homo_sapiens ENSP00000161863 75.2448 60.7692 xiphophorus_maculatus ENSXMAP00000035331 76.9671 62.1602 ENSG00000047188 homo_sapiens ENSP00000161863 64.5455 50.4895 oryzias_latipes ENSORLP00000023815 71.8847 56.2305 ENSG00000047188 homo_sapiens ENSP00000161863 76.7133 63.4266 cyclopterus_lumpus ENSCLMP00005046751 77.9673 64.4634 ENSG00000047188 homo_sapiens ENSP00000161863 74.1958 60.9091 oreochromis_niloticus ENSONIP00000054812 78.0147 64.0441 ENSG00000047188 homo_sapiens ENSP00000161863 66.5035 54.4056 haplochromis_burtoni ENSHBUP00000025445 78.7904 64.4573 ENSG00000047188 homo_sapiens ENSP00000161863 74.2657 61.6084 astatotilapia_calliptera ENSACLP00000028162 77.8592 64.5894 ENSG00000047188 homo_sapiens ENSP00000161863 76.5734 63.5664 sparus_aurata ENSSAUP00010028038 78.2702 64.975 ENSG00000047188 homo_sapiens ENSP00000161863 76.8531 63.5664 lates_calcarifer ENSLCAP00010046490 81.0472 67.0354 ENSG00000047188 homo_sapiens ENSP00000161863 89.5105 81.049 xenopus_tropicalis ENSXETP00000046516 87.8518 79.547 ENSG00000047188 homo_sapiens ENSP00000161863 96.7133 92.5175 chrysemys_picta_bellii ENSCPBP00000019151 96.781 92.5822 ENSG00000047188 homo_sapiens ENSP00000161863 48.3217 45.9441 sphenodon_punctatus ENSSPUP00000020738 94.9176 90.2473 ENSG00000047188 homo_sapiens ENSP00000161863 43.2867 41.1888 sphenodon_punctatus ENSSPUP00000020768 96.8701 92.1753 ENSG00000047188 homo_sapiens ENSP00000161863 95.3147 91.5385 crocodylus_porosus ENSCPRP00005009256 95.9859 92.1831 ENSG00000047188 homo_sapiens ENSP00000161863 57.8322 54.7552 laticauda_laticaudata ENSLLTP00000004883 94.1913 89.18 ENSG00000047188 homo_sapiens ENSP00000161863 44.4056 40.8392 notechis_scutatus ENSNSUP00000018069 87.2253 80.2198 ENSG00000047188 homo_sapiens ENSP00000161863 94.7552 90.2797 pseudonaja_textilis ENSPTXP00000001598 94.2281 89.7775 ENSG00000047188 homo_sapiens ENSP00000161863 79.8601 73.007 anas_platyrhynchos_platyrhynchos ENSAPLP00000022922 89.5686 81.8824 ENSG00000047188 homo_sapiens ENSP00000161863 89.0909 80.2098 gallus_gallus ENSGALP00010011264 88.5337 79.7081 ENSG00000047188 homo_sapiens ENSP00000161863 47.972 42.8671 meleagris_gallopavo ENSMGAP00000006726 85.5362 76.4339 ENSG00000047188 homo_sapiens ENSP00000161863 87.5524 78.8811 serinus_canaria ENSSCAP00000020449 88.9205 80.1136 ENSG00000047188 homo_sapiens ENSP00000161863 86.4336 78.4615 serinus_canaria ENSSCAP00000006388 91.0162 82.6215 ENSG00000047188 homo_sapiens ENSP00000161863 89.6504 81.3986 parus_major ENSPMJP00000016903 89.9018 81.6269 ENSG00000047188 homo_sapiens ENSP00000161863 90.0699 81.5385 parus_major ENSPMJP00000006903 90.6404 82.0549 ENSG00000047188 homo_sapiens ENSP00000161863 92.2378 88.4615 anolis_carolinensis ENSACAP00000007635 92.4965 88.7097 ENSG00000047188 homo_sapiens ENSP00000161863 72.3776 58.8112 neolamprologus_brichardi ENSNBRP00000000989 75.5474 61.3869 ENSG00000047188 homo_sapiens ENSP00000161863 89.3706 85.1748 naja_naja ENSNNAP00000003093 95.6587 91.1677 ENSG00000047188 homo_sapiens ENSP00000161863 95.035 91.2587 podarcis_muralis ENSPMRP00000018150 91.5768 87.938 ENSG00000047188 homo_sapiens ENSP00000161863 85.4545 77.4825 geospiza_fortis ENSGFOP00000003437 90.7875 82.318 ENSG00000047188 homo_sapiens ENSP00000161863 87.4825 79.2308 geospiza_fortis ENSGFOP00000009813 90.9818 82.4 ENSG00000047188 homo_sapiens ENSP00000161863 79.7203 70.5594 taeniopygia_guttata ENSTGUP00000023423 85.9728 76.0935 ENSG00000047188 homo_sapiens ENSP00000161863 70.0699 61.6783 taeniopygia_guttata ENSTGUP00000014601 80.4819 70.8434 ENSG00000047188 homo_sapiens ENSP00000161863 88.6713 79.9301 taeniopygia_guttata ENSTGUP00000003884 89.4217 80.6065 ENSG00000047188 homo_sapiens ENSP00000161863 62.2378 55.2448 taeniopygia_guttata ENSTGUP00000030079 85.086 75.5258 ENSG00000047188 homo_sapiens ENSP00000161863 78.951 69.7203 erpetoichthys_calabaricus ENSECRP00000008197 85.7903 75.7599 ENSG00000047188 homo_sapiens ENSP00000161863 76.2937 61.6084 kryptolebias_marmoratus ENSKMAP00000021540 78.0959 63.0637 ENSG00000047188 homo_sapiens ENSP00000161863 94.8252 90.7692 salvator_merianae ENSSMRP00000003269 93.1959 89.2096 ENSG00000047188 homo_sapiens ENSP00000161863 69.9301 55.3846 oryzias_javanicus ENSOJAP00000012149 72.7273 57.6 ENSG00000047188 homo_sapiens ENSP00000161863 73.8462 61.6783 amphilophus_citrinellus ENSACIP00000016490 79.638 66.5158 ENSG00000047188 homo_sapiens ENSP00000161863 76.2238 63.1469 dicentrarchus_labrax ENSDLAP00005055660 78.2484 64.8241 ENSG00000047188 homo_sapiens ENSP00000161863 75.8042 62.7972 amphiprion_percula ENSAPEP00000020971 77.263 64.0057 ENSG00000047188 homo_sapiens ENSP00000161863 93.0769 89.4406 pelodiscus_sinensis ENSPSIP00000016805 97.3665 93.5625 ENSG00000047188 homo_sapiens ENSP00000161863 93.1469 89.3706 gopherus_evgoodei ENSGEVP00005000906 97.4397 93.4894 ENSG00000047188 homo_sapiens ENSP00000161863 96.6434 92.6573 chelonoidis_abingdonii ENSCABP00000012379 96.711 92.7222 ENSG00000047188 homo_sapiens ENSP00000161863 77.8322 64.5455 seriola_dumerili ENSSDUP00000029735 77.8866 64.5906 ENSG00000047188 homo_sapiens ENSP00000161863 77.2727 63.7762 cottoperca_gobio ENSCGOP00000033263 78.985 65.1894 ENSG00000047188 homo_sapiens ENSP00000161863 92.2378 87.7622 struthio_camelus_australis ENSSCUP00000025395 96.4887 91.8069 ENSG00000047188 homo_sapiens ENSP00000161863 92.3776 84.7552 anser_brachyrhynchus ENSABRP00000003704 92.7669 85.1124 ENSG00000047188 homo_sapiens ENSP00000161863 44.3357 37.0629 gasterosteus_aculeatus ENSGACP00000024550 82.5521 69.0104 ENSG00000047188 homo_sapiens ENSP00000161863 58.8811 43.7063 cynoglossus_semilaevis ENSCSEP00000028030 69.073 51.2715 ENSG00000047188 homo_sapiens ENSP00000161863 51.8182 42.3077 poecilia_formosa ENSPFOP00000004214 78.8298 64.3617 ENSG00000047188 homo_sapiens ENSP00000161863 75.7343 61.3287 myripristis_murdjan ENSMMDP00005028909 76.6454 62.0665 ENSG00000047188 homo_sapiens ENSP00000161863 75.7343 62.028 sander_lucioperca ENSSLUP00000040777 77.1367 63.1766 ENSG00000047188 homo_sapiens ENSP00000161863 93.9161 86.5734 strigops_habroptila ENSSHBP00005004351 94.0476 86.6947 ENSG00000047188 homo_sapiens ENSP00000161863 68.6713 57.6224 amphiprion_ocellaris ENSAOCP00000013826 77.8747 65.345 ENSG00000047188 homo_sapiens ENSP00000161863 96.5734 92.5175 terrapene_carolina_triunguis ENSTMTP00000030660 96.641 92.5822 ENSG00000047188 homo_sapiens ENSP00000161863 53.4965 44.8252 hucho_hucho ENSHHUP00000067328 77.1169 64.6169 ENSG00000047188 homo_sapiens ENSP00000161863 86.8531 75.6643 hucho_hucho ENSHHUP00000011961 85.8328 74.7754 ENSG00000047188 homo_sapiens ENSP00000161863 74.1259 60.0699 betta_splendens ENSBSLP00000008071 76.1494 61.7098 ENSG00000047188 homo_sapiens ENSP00000161863 84.965 74.0559 pygocentrus_nattereri ENSPNAP00000003604 85.9265 74.8939 ENSG00000047188 homo_sapiens ENSP00000161863 75.6643 61.958 anabas_testudineus ENSATEP00000015755 77.2857 63.2857 ENSG00000047188 homo_sapiens ENSP00000161863 77.6923 64.5455 seriola_lalandi_dorsalis ENSSLDP00000029667 79.9281 66.4029 ENSG00000047188 homo_sapiens ENSP00000161863 75.9441 61.6084 labrus_bergylta ENSLBEP00000037438 62.5937 50.7781 ENSG00000047188 homo_sapiens ENSP00000161863 72.5874 58.5315 pundamilia_nyererei ENSPNYP00000009199 76.044 61.3187 ENSG00000047188 homo_sapiens ENSP00000161863 76.7832 63.8462 mastacembelus_armatus ENSMAMP00000028562 78.0384 64.8898 ENSG00000047188 homo_sapiens ENSP00000161863 75.4545 62.8671 stegastes_partitus ENSSPAP00000019782 76.9615 64.1227 ENSG00000047188 homo_sapiens ENSP00000161863 86.6434 75.8741 oncorhynchus_tshawytscha ENSOTSP00005020736 85.2719 74.6731 ENSG00000047188 homo_sapiens ENSP00000161863 35.8042 29.3706 oncorhynchus_tshawytscha ENSOTSP00005027776 78.1679 64.1221 ENSG00000047188 homo_sapiens ENSP00000161863 86.6434 75.8741 oncorhynchus_tshawytscha ENSOTSP00005072446 85.2719 74.6731 ENSG00000047188 homo_sapiens ENSP00000161863 54.965 45.4545 acanthochromis_polyacanthus ENSAPOP00000010879 75.7225 62.6204 ENSG00000047188 homo_sapiens ENSP00000161863 85.5944 78.7413 aquila_chrysaetos_chrysaetos ENSACCP00020022931 92.0301 84.6617 ENSG00000047188 homo_sapiens ENSP00000161863 93.0769 85.9441 aquila_chrysaetos_chrysaetos ENSACCP00020022745 92.9469 85.824 ENSG00000047188 homo_sapiens ENSP00000161863 74.2657 59.4406 nothobranchius_furzeri ENSNFUP00015003288 76.2383 61.0194 ENSG00000047188 homo_sapiens ENSP00000161863 74.4755 59.3706 cyprinodon_variegatus ENSCVAP00000018093 76.7844 61.2112 ENSG00000047188 homo_sapiens ENSP00000161863 80.7692 67.8322 denticeps_clupeoides ENSDCDP00000049790 82.2064 69.0391 ENSG00000047188 homo_sapiens ENSP00000161863 75.6643 61.8182 larimichthys_crocea ENSLCRP00005027913 76.09 62.166 ENSG00000047188 homo_sapiens ENSP00000161863 72.8671 58.1119 takifugu_rubripes ENSTRUP00000079349 75.837 60.4804 ENSG00000047188 homo_sapiens ENSP00000161863 83.3566 75.5245 ficedula_albicollis ENSFALP00000002733 91.2012 82.632 ENSG00000047188 homo_sapiens ENSP00000161863 87.0629 79.1608 ficedula_albicollis ENSFALP00000000042 91.2088 82.9304 ENSG00000047188 homo_sapiens ENSP00000161863 69.6504 55.1748 hippocampus_comes ENSHCOP00000024711 75.1698 59.5472 ENSG00000047188 homo_sapiens ENSP00000161863 82.6573 70.2797 cyprinus_carpio_carpio ENSCCRP00000146019 80.0271 68.0433 ENSG00000047188 homo_sapiens ENSP00000161863 87.9021 78.6713 coturnix_japonica ENSCJPP00005011161 87.6569 78.4519 ENSG00000047188 homo_sapiens ENSP00000161863 75.5944 60.8392 poecilia_latipinna ENSPLAP00000005556 77.7139 62.5449 ENSG00000047188 homo_sapiens ENSP00000161863 76.993 65.9441 sinocyclocheilus_grahami ENSSGRP00000001605 84.5622 72.427 ENSG00000047188 homo_sapiens ENSP00000161863 75.1748 61.5385 maylandia_zebra ENSMZEP00005012227 77.5054 63.4463 ENSG00000047188 homo_sapiens ENSP00000161863 68.951 54.965 tetraodon_nigroviridis ENSTNIP00000006306 74.1353 59.0977 ENSG00000047188 homo_sapiens ENSP00000161863 82.4476 69.3706 paramormyrops_kingsleyae ENSPKIP00000038122 82.3324 69.2737 ENSG00000047188 homo_sapiens ENSP00000161863 78.6014 66.0839 scleropages_formosus ENSSFOP00015005599 80.114 67.3557 ENSG00000047188 homo_sapiens ENSP00000161863 89.7203 81.8881 leptobrachium_leishanense ENSLLEP00000022306 89.9089 82.0603 ENSG00000047188 homo_sapiens ENSP00000161863 65.1049 51.5385 scophthalmus_maximus ENSSMAP00000035565 73.7718 58.3994 ENSG00000047188 homo_sapiens ENSP00000161863 69.8601 55.3846 oryzias_melastigma ENSOMEP00000012806 73.2405 58.0645
Go ID
Go term
No. evidence
Entries
Species
Category
GO:0003723 enables RNA binding 2 HDA,IBA Homo_sapiens(9606) Function GO:0004386 enables helicase activity 1 IBA Homo_sapiens(9606) Function GO:0005515 enables protein binding 1 IPI Homo_sapiens(9606) Function GO:0005524 enables ATP binding 1 IEA Homo_sapiens(9606) Function GO:0005622 is_active_in intracellular anatomical structure 1 IBA Homo_sapiens(9606) Component GO:0005783 located_in endoplasmic reticulum 1 IDA Homo_sapiens(9606) Component GO:0007286 involved_in spermatid development 1 ISS Homo_sapiens(9606) Process GO:0008186 enables ATP-dependent activity, acting on RNA 1 IDA Homo_sapiens(9606) Function GO:0016887 enables ATP hydrolysis activity 1 IEA Homo_sapiens(9606) Function GO:0034458 enables 3-5 RNA helicase activity 1 IDA Homo_sapiens(9606) Function GO:0034612 involved_in response to tumor necrosis factor 1 IDA Homo_sapiens(9606) Process GO:0035770 located_in ribonucleoprotein granule 1 ISS Homo_sapiens(9606) Component GO:0044829 involved_in positive regulation by host of viral genome replication 1 IMP Homo_sapiens(9606) Process GO:0048471 located_in perinuclear region of cytoplasm 1 IEA Homo_sapiens(9606) Component GO:0048599 involved_in oocyte development 1 ISS Homo_sapiens(9606) Process GO:0051321 involved_in meiotic cell cycle 1 IEA Homo_sapiens(9606) Process GO:0051729 involved_in germline cell cycle switching, mitotic to meiotic cell cycle 1 ISS Homo_sapiens(9606) Process GO:0070063 enables RNA polymerase binding 1 IPI Homo_sapiens(9606) Function GO:0070555 involved_in response to interleukin-1 1 IDA Homo_sapiens(9606) Process GO:1990247 enables N6-methyladenosine-containing RNA binding 1 IDA Homo_sapiens(9606) Function
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