RBP Type	Canonical_RBPs
Diseases	CancerSARS-COV-2DengueZika
Drug	N.A.
Main interacting RNAs	mRNA
Moonlighting functions	N.A.
Localizations	Stress granucleP-body
BulkPerturb-seq	DataSet_02_78

Ensembl ID	ENSG00000040341	Gene ID	27067	Accession	11371
Symbol	STAU2	Alias	39K2;39K3	Full Name	staufen double-stranded RNA binding protein 2
Status	Confidence	Length	327340 bases	Strand	Minus strand
Position	8 : 73420369 - 73747708	RNA binding domain	dsrm , Staufen_C
Summary	Staufen homolog 2 is a member of the family of double-stranded RNA (dsRNA)-binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles. These proteins are characterized by the presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary structures. Staufen homolog 2 shares 48.5% and 59.9% similarity with drosophila and human staufen, respectively. The exact function of Staufen homolog 2 is not known, but since it contains 3 copies of conserved dsRNA binding domain, it could be involved in double-stranded RNA binding events. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2009]