RBP Type
Canonical_RBPs
Diseases
CancerSARS-COV-2 Dengue Zika
Drug
N.A.
Main interacting RNAs
mRNA
Moonlighting functions
N.A.
Localizations
Stress granucle P-body
BulkPerturb-seq
DataSet_02_78
Ensembl ID ENSG00000040341 Gene ID
27067
Accession
11371
Symbol
STAU2
Alias
39K2;39K3
Full Name
staufen double-stranded RNA binding protein 2
Status
Confidence
Length
327340 bases
Strand
Minus strand
Position
8 : 73420369 - 73747708
RNA binding domain
dsrm , Staufen_C
Summary
Staufen homolog 2 is a member of the family of double-stranded RNA (dsRNA)-binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles. These proteins are characterized by the presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary structures. Staufen homolog 2 shares 48.5% and 59.9% similarity with drosophila and human staufen, respectively. The exact function of Staufen homolog 2 is not known, but since it contains 3 copies of conserved dsRNA binding domain, it could be involved in double-stranded RNA binding events. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2009]
RNA binding domains (RBDs)
Protein
Domain
Pfam ID
E-value
Domain number
ENSP00000429173
Staufen_C
PF16482
1.1e-42
1
ENSP00000429173
dsrm
PF00035
4.8e-36
2
ENSP00000429173
dsrm
PF00035
4.8e-36
3
ENSP00000429173
dsrm
PF00035
4.8e-36
4
ENSP00000430511
Staufen_C
PF16482
3.2e-35
1
ENSP00000428741
Staufen_C
PF16482
3.6e-18
1
ENSP00000428741
dsrm
PF00035
1.2e-27
2
ENSP00000428741
dsrm
PF00035
1.2e-27
3
ENSP00000428476
Staufen_C
PF16482
6.3e-18
1
ENSP00000428476
dsrm
PF00035
1.6e-25
2
ENSP00000428476
dsrm
PF00035
1.6e-25
3
ENSP00000431111
Staufen_C
PF16482
2.8e-17
1
ENSP00000431111
dsrm
PF00035
6.8e-38
2
ENSP00000431111
dsrm
PF00035
6.8e-38
3
ENSP00000431111
dsrm
PF00035
6.8e-38
4
ENSP00000348026
Staufen_C
PF16482
3e-17
1
ENSP00000348026
dsrm
PF00035
1.8e-38
2
ENSP00000348026
dsrm
PF00035
1.8e-38
3
ENSP00000348026
dsrm
PF00035
1.8e-38
4
ENSP00000427977
Staufen_C
PF16482
3e-17
1
ENSP00000427977
dsrm
PF00035
1.8e-38
2
ENSP00000427977
dsrm
PF00035
1.8e-38
3
ENSP00000427977
dsrm
PF00035
1.8e-38
4
ENSP00000429973
Staufen_C
PF16482
4.3e-17
1
ENSP00000429973
dsrm
PF00035
1.2e-39
2
ENSP00000429973
dsrm
PF00035
1.2e-39
3
ENSP00000429973
dsrm
PF00035
1.2e-39
4
ENSP00000430907
Staufen_C
PF16482
4.8e-17
1
ENSP00000430907
dsrm
PF00035
4.4e-45
2
ENSP00000430907
dsrm
PF00035
4.4e-45
3
ENSP00000430907
dsrm
PF00035
4.4e-45
4
ENSP00000430907
dsrm
PF00035
4.4e-45
5
ENSP00000428456
Staufen_C
PF16482
5.7e-17
1
ENSP00000428456
dsrm
PF00035
2.7e-38
2
ENSP00000428456
dsrm
PF00035
2.7e-38
3
ENSP00000428456
dsrm
PF00035
2.7e-38
4
ENSP00000428756
Staufen_C
PF16482
9.9e-17
1
ENSP00000428756
dsrm
PF00035
5e-45
2
ENSP00000428756
dsrm
PF00035
5e-45
3
ENSP00000428756
dsrm
PF00035
5e-45
4
ENSP00000428756
dsrm
PF00035
5e-45
5
ENSP00000428664
dsrm
PF00035
3.5e-40
1
ENSP00000428664
dsrm
PF00035
3.5e-40
2
ENSP00000428664
dsrm
PF00035
3.5e-40
3
ENSP00000429005
dsrm
PF00035
7.6e-28
1
ENSP00000429005
dsrm
PF00035
7.6e-28
2
ENSP00000428829
dsrm
PF00035
6.6e-13
1
ENSP00000428284
dsrm
PF00035
1.2e-05
1
RNA binding proteomes (RBPomes)
Pubmed ID
Full Name
Cell
Author
Time
Doi
Literatures on RNA binding capacity
Pubmed ID
Title
Author
Time
Journal
36834668
Quantitative Proteomics of Human Retinal Pigment Epithelium Reveals Key Regulators for the Pathogenesis of Age-Related Macular Degeneration.
Shichen Shen
2023-02-07
International journal of molecular sciences
26843428
The downregulation of the RNA-binding protein Staufen2 in response to DNA damage promotes apoptosis.
Xin Zhang
2016-05-05
Nucleic acids research
15166236
The brain-specific double-stranded RNA-binding protein Staufen2: nucleolar accumulation and isoform-specific exportin-5-dependent export.
Paolo Macchi
2004-07-23
The Journal of biological chemistry
28765142
A retained intron in the 3'-UTR of Calm3 mRNA mediates its Staufen2- and activity-dependent localization to neuronal dendrites.
Tejaswini Sharangdhar
2017-10-01
EMBO reports
33594163
Rare deleterious germline variants and risk of lung cancer.
Yanhong Liu
2021-02-16
NPJ precision oncology
15364930
Alternative splicing of Staufen2 creates the nuclear export signal for CRM1 (Exportin 1).
Takashi Miki
2004-11-12
The Journal of biological chemistry
24685002
Long noncoding RNAs, emerging players in muscle differentiation and disease.
Victoria Maria Neguembor
2014-03-31
Skeletal muscle
28821679
UPF1 Governs Synaptic Plasticity through Association with a STAU2 RNA Granule.
E Tyson Graber
2017-09-20
The Journal of neuroscience : the official journal of the Society for Neuroscience
35687120
The dsRBP Staufen2 governs RNP assembly of neuronal Argonaute proteins.
Janina Ehses
2022-07-08
Nucleic acids research
33159345
Low expression of hsa_circ_0001811 in gastric cancer and its role in clinical diagnosis.
Haiyan Zhang
2021-02-01
Journal of clinical laboratory analysis
28077174
Mutant HSPB1 causes loss of translational repression by binding to PCBP1, an RNA binding protein with a possible role in neurodegenerative disease.
Thomas Geuens
2017-01-11
Acta neuropathologica communications
28304078
Moving messages in the developing brain-emerging roles for mRNA transport and local translation in neural stem cells.
Louis-Jan Pilaz
2017-06-01
FEBS letters
36183486
Whole genome sequencing identifies candidate genes for familial essential tremor and reveals biological pathways implicated in essential tremor aetiology.
N Lorraine Clark
2022-11-01
EBioMedicine
35383181
acorde unravels functionally interpretable networks of isoform co-usage from single cell data.
Angeles Arzalluz-Luque
2022-04-05
Nature communications
34499710
Inheritance and flexibility of cell polarity: a clue for understanding human brain development and evolution.
Nereo Kalebic
2021-09-01
Development (Cambridge, England)
30744035
Staufen1 Protein Participates Positively in the Viral RNA Replication of Enterovirus 71.
Young-Mao Chen
2019-02-08
Viruses
Name
Transcript ID
bp
Protein
Translation ID
STAU2-220
ENST00000522695
2646
538aa
ENSP00000428456
STAU2-229
ENST00000524300
2970
570aa
ENSP00000428756
STAU2-221
ENST00000522818
707
No protein
-
STAU2-225
ENST00000523558
1603
398aa
ENSP00000428741
STAU2-210
ENST00000521210
1950
504aa
ENSP00000429173
STAU2-224
ENST00000523533
805
162aa
ENSP00000430511
STAU2-201
ENST00000355780
4061
479aa
ENSP00000348026
STAU2-207
ENST00000519961
3928
511aa
ENSP00000430907
STAU2-215
ENST00000521727
3953
491aa
ENSP00000429973
STAU2-214
ENST00000521451
2712
291aa
ENSP00000428476
STAU2-219
ENST00000522509
2173
479aa
ENSP00000427977
STAU2-202
ENST00000517542
1695
473aa
ENSP00000431111
STAU2-205
ENST00000518981
1746
390aa
ENSP00000428664
STAU2-204
ENST00000518767
1146
320aa
ENSP00000429005
STAU2-203
ENST00000518502
687
135aa
ENSP00000428284
STAU2-211
ENST00000521293
552
No protein
-
STAU2-213
ENST00000521447
727
204aa
ENSP00000428829
STAU2-226
ENST00000524104
2173
105aa
ENSP00000430611
STAU2-222
ENST00000522962
1041
No protein
-
STAU2-212
ENST00000521419
972
125aa
ENSP00000428681
STAU2-228
ENST00000524191
808
No protein
-
STAU2-227
ENST00000524113
658
No protein
-
STAU2-209
ENST00000520945
472
No protein
-
STAU2-216
ENST00000521736
550
63aa
ENSP00000428737
STAU2-217
ENST00000521845
546
No protein
-
STAU2-208
ENST00000520872
560
No protein
-
STAU2-206
ENST00000519818
590
No protein
-
STAU2-218
ENST00000522061
564
No protein
-
STAU2-223
ENST00000523160
227
No protein
-
Pathway ID
Pathway Name
Source
ensgID
Trait
pValue
Pubmed ID
931 Body Mass Index 1.83562911670876E-5 17903300 932 Body Mass Index 6.60732952588727E-5 17903300 933 Body Mass Index 1.46424174019E-5 17903300 946 Body Weight Changes 4.27668651823421E-5 17903300 947 Body Weight Changes 4.14939035831008E-5 17903300 948 Body Weight Changes 3.56503472795922E-5 17903300 1215 Body Mass Index 8.23429211149751E-6 17903300 1216 Body Mass Index 2.80186399983506E-5 17903300 1217 Body Mass Index 6.83377798271767E-5 17903300 1218 Body Mass Index 6.24264842929989E-6 17903300 1230 Body Weight Changes 2.88955969929283E-5 17903300 1231 Body Weight Changes 2.55370688275747E-5 17903300 1232 Body Weight Changes 2.3369131189499E-5 17903300 12940 Multiple Sclerosis 1.9E-5 19010793 50676 Child Development Disorders, Pervasive 3.1523100E-005 - 90405 Pelvic Organ Prolapse 8E-7 26545240 90491 Axial Length, Eye 9E-6 24144296
ensgID SNP Chromosome Position
Trait PubmedID Or or BEAT
EFO ID
Protein-Protein Interaction (PPI)
Ensembl ID
Source
Target
Species
Protein ID
Perc_pos
Perc_id
Species
Protein ID
Perc_pos
Perc_id
ENSG00000040341 homo_sapiens ENSP00000468181 10.9131 5.56793 homo_sapiens ENSP00000428756 17.193 8.77193 ENSG00000040341 homo_sapiens ENSP00000457501 20.5179 9.36255 homo_sapiens ENSP00000428756 18.0702 8.24561 ENSG00000040341 homo_sapiens ENSP00000265069 14.0596 7.35568 homo_sapiens ENSP00000428756 26.4912 13.8596 ENSG00000040341 homo_sapiens ENSP00000321347 15.1786 8.18452 homo_sapiens ENSP00000428756 17.8947 9.64912 ENSG00000040341 homo_sapiens ENSP00000355011 23.3333 12.8205 homo_sapiens ENSP00000428756 15.9649 8.77193 ENSG00000040341 homo_sapiens ENSP00000015877 24.1084 13.5521 homo_sapiens ENSP00000428756 29.6491 16.6667 ENSG00000040341 homo_sapiens ENSP00000262961 15.5485 7.13525 homo_sapiens ENSP00000428756 25.614 11.7544 ENSG00000040341 homo_sapiens ENSP00000325153 20.5832 9.77702 homo_sapiens ENSP00000428756 21.0526 10 ENSG00000040341 homo_sapiens ENSP00000296513 22.3958 11.2847 homo_sapiens ENSP00000428756 22.6316 11.4035 ENSG00000040341 homo_sapiens ENSP00000360922 51.8198 41.9411 homo_sapiens ENSP00000428756 52.4561 42.4561 ENSG00000040341 homo_sapiens ENSP00000370713 22.5981 11.908 homo_sapiens ENSP00000428756 29.2982 15.4386 ENSG00000040341 homo_sapiens ENSP00000318176 26.1981 16.2939 homo_sapiens ENSP00000428756 14.386 8.94737 ENSG00000040341 homo_sapiens ENSP00000357459 14.0294 7.58564 homo_sapiens ENSP00000428756 30.1754 16.3158 ENSG00000040341 homo_sapiens ENSP00000266987 27.3224 15.847 homo_sapiens ENSP00000428756 17.5439 10.1754
Ensembl ID
Source
Target
Species
Protein ID
Perc_pos
Perc_id
Species
Protein ID
Perc_pos
Perc_id
ENSG00000040341 homo_sapiens ENSP00000428756 99.4737 99.2982 nomascus_leucogenys ENSNLEP00000001842 99.4737 99.2982 ENSG00000040341 homo_sapiens ENSP00000428756 100 99.8246 pan_paniscus ENSPPAP00000022501 93.75 93.5855 ENSG00000040341 homo_sapiens ENSP00000428756 100 99.6491 pongo_abelii ENSPPYP00000032692 92.5325 92.2078 ENSG00000040341 homo_sapiens ENSP00000428756 93.6842 92.9825 pan_troglodytes ENSPTRP00000064136 92.7083 92.0139 ENSG00000040341 homo_sapiens ENSP00000428756 99.8246 99.6491 gorilla_gorilla ENSGGOP00000042304 99.8246 99.6491 ENSG00000040341 homo_sapiens ENSP00000428756 81.7544 72.4561 ornithorhynchus_anatinus ENSOANP00000053057 65.1748 57.7622 ENSG00000040341 homo_sapiens ENSP00000428756 65.4386 59.2982 sarcophilus_harrisii ENSSHAP00000014107 80.0429 72.5322 ENSG00000040341 homo_sapiens ENSP00000428756 47.7193 43.1579 notamacropus_eugenii ENSMEUP00000010350 47.8032 43.2337 ENSG00000040341 homo_sapiens ENSP00000428756 76.4912 74.7368 choloepus_hoffmanni ENSCHOP00000009371 76.4912 74.7368 ENSG00000040341 homo_sapiens ENSP00000428756 98.2456 95.9649 dasypus_novemcinctus ENSDNOP00000032499 98.2456 95.9649 ENSG00000040341 homo_sapiens ENSP00000428756 96.6667 94.7368 erinaceus_europaeus ENSEEUP00000013786 96.8366 94.9033 ENSG00000040341 homo_sapiens ENSP00000428756 89.6491 86.8421 echinops_telfairi ENSETEP00000007370 89.8067 86.9947 ENSG00000040341 homo_sapiens ENSP00000428756 99.2982 98.5965 callithrix_jacchus ENSCJAP00000014184 99.2982 98.5965 ENSG00000040341 homo_sapiens ENSP00000428756 95.614 94.2105 cercocebus_atys ENSCATP00000044731 88.3306 87.034 ENSG00000040341 homo_sapiens ENSP00000428756 100 99.6491 macaca_fascicularis ENSMFAP00000026854 93.75 93.4211 ENSG00000040341 homo_sapiens ENSP00000428756 94.0351 93.5088 macaca_nemestrina ENSMNEP00000023801 99.6283 99.0706 ENSG00000040341 homo_sapiens ENSP00000428756 100 99.8246 papio_anubis ENSPANP00000048746 93.75 93.5855 ENSG00000040341 homo_sapiens ENSP00000428756 100 99.6491 mandrillus_leucophaeus ENSMLEP00000040808 100 99.6491 ENSG00000040341 homo_sapiens ENSP00000428756 88.4211 86.6667 tursiops_truncatus ENSTTRP00000008760 88.4211 86.6667 ENSG00000040341 homo_sapiens ENSP00000428756 98.2456 96.4912 vulpes_vulpes ENSVVUP00000026450 92.1053 90.4605 ENSG00000040341 homo_sapiens ENSP00000428756 21.0526 18.5965 vulpes_vulpes ENSVVUP00000023565 82.1918 72.6027 ENSG00000040341 homo_sapiens ENSP00000428756 97.3684 93.6842 mus_spretus MGP_SPRETEiJ_P0017789 97.3684 93.6842 ENSG00000040341 homo_sapiens ENSP00000428756 98.0702 95.7895 equus_asinus ENSEASP00005029679 89.2971 87.2204 ENSG00000040341 homo_sapiens ENSP00000428756 98.0702 96.1404 capra_hircus ENSCHIP00000009412 89.0127 87.2611 ENSG00000040341 homo_sapiens ENSP00000428756 98.5965 97.0175 loxodonta_africana ENSLAFP00000011153 98.5965 97.0175 ENSG00000040341 homo_sapiens ENSP00000428756 90.5263 88.5965 panthera_leo ENSPLOP00000006797 89.7391 87.8261 ENSG00000040341 homo_sapiens ENSP00000428756 98.4211 96.6667 ailuropoda_melanoleuca ENSAMEP00000038191 89.4737 87.8788 ENSG00000040341 homo_sapiens ENSP00000428756 97.7193 95.9649 bos_indicus_hybrid ENSBIXP00005014499 88.9776 87.3802 ENSG00000040341 homo_sapiens ENSP00000428756 98.4211 97.3684 oryctolagus_cuniculus ENSOCUP00000045089 86.3077 85.3846 ENSG00000040341 homo_sapiens ENSP00000428756 98.0702 95.9649 equus_caballus ENSECAP00000054411 89.2971 87.3802 ENSG00000040341 homo_sapiens ENSP00000428756 94.0351 90.8772 canis_lupus_familiaris ENSCAFP00845039393 59.7547 57.7481 ENSG00000040341 homo_sapiens ENSP00000428756 98.4211 96.6667 panthera_pardus ENSPPRP00000000448 98.4211 96.6667 ENSG00000040341 homo_sapiens ENSP00000428756 98.5965 96.8421 marmota_marmota_marmota ENSMMMP00000005812 86.3287 84.7926 ENSG00000040341 homo_sapiens ENSP00000428756 88.2456 86.8421 balaenoptera_musculus ENSBMSP00010020646 98.6274 97.0588 ENSG00000040341 homo_sapiens ENSP00000428756 98.0702 96.3158 cavia_porcellus ENSCPOP00000013518 98.0702 96.3158 ENSG00000040341 homo_sapiens ENSP00000428756 94.2105 91.5789 felis_catus ENSFCAP00000029531 78.5088 76.3158 ENSG00000040341 homo_sapiens ENSP00000428756 18.2456 17.7193 ursus_americanus ENSUAMP00000024501 89.6552 87.069 ENSG00000040341 homo_sapiens ENSP00000428756 84.2105 75.4386 monodelphis_domestica ENSMODP00000041997 77.7958 69.6921 ENSG00000040341 homo_sapiens ENSP00000428756 98.0702 96.1404 bison_bison_bison ENSBBBP00000025246 98.0702 96.1404 ENSG00000040341 homo_sapiens ENSP00000428756 97.7193 95.614 monodon_monoceros ENSMMNP00015003198 91.6118 89.6382 ENSG00000040341 homo_sapiens ENSP00000428756 97.8947 96.1404 sus_scrofa ENSSSCP00000039405 88.2911 86.7089 ENSG00000040341 homo_sapiens ENSP00000428756 97.5439 95.2632 microcebus_murinus ENSMICP00000002628 97.7153 95.4306 ENSG00000040341 homo_sapiens ENSP00000428756 98.0702 96.4912 octodon_degus ENSODEP00000004751 98.0702 96.4912 ENSG00000040341 homo_sapiens ENSP00000428756 87.7193 86.1404 jaculus_jaculus ENSJJAP00000019206 97.8474 96.0861 ENSG00000040341 homo_sapiens ENSP00000428756 98.0702 96.1404 ovis_aries_rambouillet ENSOARP00020016781 86.6667 84.9612 ENSG00000040341 homo_sapiens ENSP00000428756 18.9474 18.5965 ovis_aries_rambouillet ENSOARP00020018085 90.7563 89.0756 ENSG00000040341 homo_sapiens ENSP00000428756 98.4211 96.6667 ursus_maritimus ENSUMAP00000026029 89.4737 87.8788 ENSG00000040341 homo_sapiens ENSP00000428756 88.7719 86.1404 ochotona_princeps ENSOPRP00000007758 89.2416 86.5961 ENSG00000040341 homo_sapiens ENSP00000428756 93.6842 90.7018 delphinapterus_leucas ENSDLEP00000012940 74.8948 72.5105 ENSG00000040341 homo_sapiens ENSP00000428756 97.3684 94.9123 physeter_catodon ENSPCTP00005016578 91.2829 88.9803 ENSG00000040341 homo_sapiens ENSP00000428756 97.5439 93.6842 mus_caroli MGP_CAROLIEiJ_P0016800 97.5439 93.6842 ENSG00000040341 homo_sapiens ENSP00000428756 97.5439 93.8596 mus_musculus ENSMUSP00000124505 97.5439 93.8596 ENSG00000040341 homo_sapiens ENSP00000428756 92.2807 89.8246 dipodomys_ordii ENSDORP00000013458 98.1343 95.5224 ENSG00000040341 homo_sapiens ENSP00000428756 98.4211 96.6667 mustela_putorius_furo ENSMPUP00000010146 92.2697 90.625 ENSG00000040341 homo_sapiens ENSP00000428756 99.2982 98.7719 aotus_nancymaae ENSANAP00000011469 93.0921 92.5987 ENSG00000040341 homo_sapiens ENSP00000428756 99.2982 98.5965 saimiri_boliviensis_boliviensis ENSSBOP00000032309 93.0921 92.4342 ENSG00000040341 homo_sapiens ENSP00000428756 97.3684 95.2632 vicugna_pacos ENSVPAP00000001403 97.5395 95.4306 ENSG00000040341 homo_sapiens ENSP00000428756 98.0702 95.7895 tupaia_belangeri ENSTBEP00000014131 98.5891 96.2963 ENSG00000040341 homo_sapiens ENSP00000428756 83.3333 80.1754 mesocricetus_auratus ENSMAUP00000024947 96.7413 93.0754 ENSG00000040341 homo_sapiens ENSP00000428756 97.8947 95.7895 phocoena_sinus ENSPSNP00000007049 91.7763 89.8026 ENSG00000040341 homo_sapiens ENSP00000428756 97.3684 95.4386 camelus_dromedarius ENSCDRP00005017426 85.3846 83.6923 ENSG00000040341 homo_sapiens ENSP00000428756 98.4211 96.6667 panthera_tigris_altaica ENSPTIP00000005757 92.2697 90.625 ENSG00000040341 homo_sapiens ENSP00000428756 96.6667 93.5088 rattus_norvegicus ENSRNOP00000092247 96.4974 93.345 ENSG00000040341 homo_sapiens ENSP00000428756 97.8947 96.4912 prolemur_simus ENSPSMP00000018156 91.4754 90.1639 ENSG00000040341 homo_sapiens ENSP00000428756 94.386 91.2281 microtus_ochrogaster ENSMOCP00000001391 97.9964 94.7177 ENSG00000040341 homo_sapiens ENSP00000428756 53.3333 51.5789 sorex_araneus ENSSARP00000008849 57.1429 55.2632 ENSG00000040341 homo_sapiens ENSP00000428756 97.7193 94.386 peromyscus_maniculatus_bairdii ENSPEMP00000011481 97.7193 94.386 ENSG00000040341 homo_sapiens ENSP00000428756 97.8947 95.9649 bos_mutus ENSBMUP00000013350 88.9952 87.2408 ENSG00000040341 homo_sapiens ENSP00000428756 97.3684 93.6842 mus_spicilegus ENSMSIP00000009710 97.3684 93.6842 ENSG00000040341 homo_sapiens ENSP00000428756 97.5439 94.2105 cricetulus_griseus_chok1gshd ENSCGRP00001005041 97.5439 94.2105 ENSG00000040341 homo_sapiens ENSP00000428756 87.8947 84.7368 pteropus_vampyrus ENSPVAP00000013740 88.0492 84.8858 ENSG00000040341 homo_sapiens ENSP00000428756 87.8947 86.4912 myotis_lucifugus ENSMLUP00000000537 98.2353 96.6667 ENSG00000040341 homo_sapiens ENSP00000428756 90.7018 81.7544 vombatus_ursinus ENSVURP00010021908 81.1617 73.1554 ENSG00000040341 homo_sapiens ENSP00000428756 90.7018 81.7544 vombatus_ursinus ENSVURP00010027864 81.1617 73.1554 ENSG00000040341 homo_sapiens ENSP00000428756 97.8947 95.614 rhinolophus_ferrumequinum ENSRFEP00010013339 98.0668 95.7821 ENSG00000040341 homo_sapiens ENSP00000428756 98.2456 96.4912 neovison_vison ENSNVIP00000019773 92.1053 90.4605 ENSG00000040341 homo_sapiens ENSP00000428756 98.0702 96.1404 bos_taurus ENSBTAP00000066503 91.9408 90.1316 ENSG00000040341 homo_sapiens ENSP00000428756 97.193 95.7895 heterocephalus_glaber_female ENSHGLP00000056424 87.5197 86.2559 ENSG00000040341 homo_sapiens ENSP00000428756 98.2456 96.4912 canis_lupus_dingo ENSCAFP00020022569 92.1053 90.4605 ENSG00000040341 homo_sapiens ENSP00000428756 98.4211 96.6667 sciurus_vulgaris ENSSVLP00005002706 98.7676 97.007 ENSG00000040341 homo_sapiens ENSP00000428756 84.9123 74.7368 phascolarctos_cinereus ENSPCIP00000016749 75.2722 66.2519 ENSG00000040341 homo_sapiens ENSP00000428756 80.1754 78.4211 procavia_capensis ENSPCAP00000004371 89.6078 87.6471 ENSG00000040341 homo_sapiens ENSP00000428756 97.8947 95.0877 nannospalax_galili ENSNGAP00000017475 97.8947 95.0877 ENSG00000040341 homo_sapiens ENSP00000428756 98.0702 96.1404 bos_grunniens ENSBGRP00000023165 89.1547 87.4003 ENSG00000040341 homo_sapiens ENSP00000428756 97.7193 95.4386 chinchilla_lanigera ENSCLAP00000002518 95.2137 92.9915 ENSG00000040341 homo_sapiens ENSP00000428756 98.0702 95.9649 cervus_hanglu_yarkandensis ENSCHYP00000014173 89.1547 87.2408 ENSG00000040341 homo_sapiens ENSP00000428756 97.3684 95.7895 catagonus_wagneri ENSCWAP00000026125 97.5395 95.9578 ENSG00000040341 homo_sapiens ENSP00000428756 98.5965 96.6667 ictidomys_tridecemlineatus ENSSTOP00000009939 92.5865 90.7743 ENSG00000040341 homo_sapiens ENSP00000428756 64.7368 63.8596 otolemur_garnettii ENSOGAP00000000989 98.9276 97.5871 ENSG00000040341 homo_sapiens ENSP00000428756 98.5965 96.8421 urocitellus_parryii ENSUPAP00010013996 92.5865 90.939 ENSG00000040341 homo_sapiens ENSP00000428756 98.0702 96.1404 moschus_moschiferus ENSMMSP00000013581 84.4411 82.7795 ENSG00000040341 homo_sapiens ENSP00000428756 97.3684 92.807 mus_pahari MGP_PahariEiJ_P0056693 97.3684 92.807 ENSG00000040341 homo_sapiens ENSP00000428756 85.2632 83.5088 propithecus_coquereli ENSPCOP00000003975 97.5904 95.5823 ENSG00000040341 homo_sapiens ENSP00000428756 25.0877 11.2281 caenorhabditis_elegans Y95B8A.8.1 18.7173 8.37696 ENSG00000040341 homo_sapiens ENSP00000428756 19.1228 11.2281 drosophila_melanogaster FBpp0080076 23.4409 13.7634 ENSG00000040341 homo_sapiens ENSP00000428756 13.3333 7.01754 drosophila_melanogaster FBpp0076856 23.4568 12.3457 ENSG00000040341 homo_sapiens ENSP00000428756 12.4561 6.31579 drosophila_melanogaster FBpp0073219 23.9865 12.1622 ENSG00000040341 homo_sapiens ENSP00000428756 22.6316 10.8772 drosophila_melanogaster FBpp0305489 14.5928 7.01357 ENSG00000040341 homo_sapiens ENSP00000428756 12.6316 6.84211 ciona_intestinalis ENSCINP00000012805 24 13 ENSG00000040341 homo_sapiens ENSP00000428756 11.4035 4.73684 ciona_intestinalis ENSCINP00000034518 17.4263 7.23861 ENSG00000040341 homo_sapiens ENSP00000428756 22.807 10 ciona_intestinalis ENSCINP00000010046 13.7276 6.01901 ENSG00000040341 homo_sapiens ENSP00000428756 17.8947 8.07018 ciona_intestinalis ENSCINP00000026042 12.2302 5.51559 ENSG00000040341 homo_sapiens ENSP00000428756 70.8772 58.2456 petromyzon_marinus ENSPMAP00000004194 66.0131 54.2484 ENSG00000040341 homo_sapiens ENSP00000428756 39.6491 28.2456 eptatretus_burgeri ENSEBUP00000010279 59.7884 42.5926 ENSG00000040341 homo_sapiens ENSP00000428756 86.3158 75.9649 callorhinchus_milii ENSCMIP00000004105 71.3043 62.7536 ENSG00000040341 homo_sapiens ENSP00000428756 89.2982 80.3509 latimeria_chalumnae ENSLACP00000007759 73.8752 66.4732 ENSG00000040341 homo_sapiens ENSP00000428756 68.4211 58.0702 lepisosteus_oculatus ENSLOCP00000004427 62.9032 53.3871 ENSG00000040341 homo_sapiens ENSP00000428756 83.5088 72.9825 clupea_harengus ENSCHAP00000048767 68.1948 59.5989 ENSG00000040341 homo_sapiens ENSP00000428756 85.614 73.6842 danio_rerio ENSDARP00000116175 71.9764 61.9469 ENSG00000040341 homo_sapiens ENSP00000428756 84.386 73.1579 carassius_auratus ENSCARP00000116986 70.944 61.5044 ENSG00000040341 homo_sapiens ENSP00000428756 85.2632 74.5614 carassius_auratus ENSCARP00000091748 71.6814 62.6844 ENSG00000040341 homo_sapiens ENSP00000428756 85.7895 74.5614 astyanax_mexicanus ENSAMXP00000000463 72.5519 63.0564 ENSG00000040341 homo_sapiens ENSP00000428756 81.4035 68.9474 ictalurus_punctatus ENSIPUP00000013413 70.1967 59.4554 ENSG00000040341 homo_sapiens ENSP00000428756 80.1754 69.2982 esox_lucius ENSELUP00000078058 66.2319 57.2464 ENSG00000040341 homo_sapiens ENSP00000428756 84.7368 73.1579 electrophorus_electricus ENSEEEP00000007760 71.3442 61.5953 ENSG00000040341 homo_sapiens ENSP00000428756 76.8421 67.8947 oncorhynchus_kisutch ENSOKIP00005098163 68.2243 60.2804 ENSG00000040341 homo_sapiens ENSP00000428756 78.2456 68.0702 oncorhynchus_mykiss ENSOMYP00000125624 62.5526 54.418 ENSG00000040341 homo_sapiens ENSP00000428756 78.9474 68.7719 salmo_salar ENSSSAP00000151799 67.1642 58.5075 ENSG00000040341 homo_sapiens ENSP00000428756 13.1579 8.77193 salmo_trutta ENSSTUP00000048910 72.8155 48.5437 ENSG00000040341 homo_sapiens ENSP00000428756 58.5965 46.8421 gadus_morhua ENSGMOP00000033803 69.0083 55.1653 ENSG00000040341 homo_sapiens ENSP00000428756 13.5088 10.5263 gadus_morhua ENSGMOP00000037155 68.75 53.5714 ENSG00000040341 homo_sapiens ENSP00000428756 51.4035 45.4386 fundulus_heteroclitus ENSFHEP00000016672 77.9255 68.883 ENSG00000040341 homo_sapiens ENSP00000428756 81.4035 68.7719 poecilia_reticulata ENSPREP00000026316 65.0771 54.979 ENSG00000040341 homo_sapiens ENSP00000428756 80 68.7719 xiphophorus_maculatus ENSXMAP00000035613 68.1614 58.5949 ENSG00000040341 homo_sapiens ENSP00000428756 80.8772 68.4211 oryzias_latipes ENSORLP00000009963 66.3309 56.1151 ENSG00000040341 homo_sapiens ENSP00000428756 79.4737 67.0175 cyclopterus_lumpus ENSCLMP00005028348 65.5572 55.2822 ENSG00000040341 homo_sapiens ENSP00000428756 81.2281 69.4737 oreochromis_niloticus ENSONIP00000076054 68.0882 58.2353 ENSG00000040341 homo_sapiens ENSP00000428756 81.2281 69.2982 haplochromis_burtoni ENSHBUP00000018088 68.0882 58.0882 ENSG00000040341 homo_sapiens ENSP00000428756 81.2281 69.2982 astatotilapia_calliptera ENSACLP00000035989 68.0882 58.0882 ENSG00000040341 homo_sapiens ENSP00000428756 81.2281 69.1228 sparus_aurata ENSSAUP00010051673 69.2078 58.8939 ENSG00000040341 homo_sapiens ENSP00000428756 79.1228 67.5439 lates_calcarifer ENSLCAP00010032097 75.0416 64.0599 ENSG00000040341 homo_sapiens ENSP00000428756 84.2105 72.9825 xenopus_tropicalis ENSXETP00000100758 66.1157 57.3003 ENSG00000040341 homo_sapiens ENSP00000428756 92.1053 85.2632 chrysemys_picta_bellii ENSCPBP00000009030 75.1073 69.5279 ENSG00000040341 homo_sapiens ENSP00000428756 76.6667 71.2281 sphenodon_punctatus ENSSPUP00000023745 74.9571 69.6398 ENSG00000040341 homo_sapiens ENSP00000428756 91.9298 85.0877 crocodylus_porosus ENSCPRP00005026520 77.1723 71.4286 ENSG00000040341 homo_sapiens ENSP00000428756 92.6316 85.7895 anas_platyrhynchos_platyrhynchos ENSAPLP00000023808 75.6447 70.0573 ENSG00000040341 homo_sapiens ENSP00000428756 92.9825 85.614 gallus_gallus ENSGALP00010005050 83.5962 76.9716 ENSG00000040341 homo_sapiens ENSP00000428756 18.4211 16.3158 meleagris_gallopavo ENSMGAP00000012077 89.7436 79.4872 ENSG00000040341 homo_sapiens ENSP00000428756 15.2632 13.3333 meleagris_gallopavo ENSMGAP00000022072 79.0909 69.0909 ENSG00000040341 homo_sapiens ENSP00000428756 92.2807 85.0877 serinus_canaria ENSSCAP00000002476 77.3529 71.3235 ENSG00000040341 homo_sapiens ENSP00000428756 86.8421 80 parus_major ENSPMJP00000006111 72.6872 66.9604 ENSG00000040341 homo_sapiens ENSP00000428756 86.4912 75.614 anolis_carolinensis ENSACAP00000012767 59.6852 52.1792 ENSG00000040341 homo_sapiens ENSP00000428756 81.2281 69.2982 neolamprologus_brichardi ENSNBRP00000031366 69.4153 59.2204 ENSG00000040341 homo_sapiens ENSP00000428756 89.8246 80.7018 podarcis_muralis ENSPMRP00000011360 75.2941 67.6471 ENSG00000040341 homo_sapiens ENSP00000428756 83.8596 77.5439 geospiza_fortis ENSGFOP00000017119 89.6811 82.9268 ENSG00000040341 homo_sapiens ENSP00000428756 92.6316 85.4386 taeniopygia_guttata ENSTGUP00000027884 77.6471 71.6176 ENSG00000040341 homo_sapiens ENSP00000428756 86.4912 77.8947 erpetoichthys_calabaricus ENSECRP00000007931 73.2541 65.9733 ENSG00000040341 homo_sapiens ENSP00000428756 79.6491 68.9474 kryptolebias_marmoratus ENSKMAP00000009158 67.7612 58.6567 ENSG00000040341 homo_sapiens ENSP00000428756 88.4211 79.8246 salvator_merianae ENSSMRP00000014333 72.518 65.4676 ENSG00000040341 homo_sapiens ENSP00000428756 79.8246 68.7719 oryzias_javanicus ENSOJAP00000043915 66.23 57.0597 ENSG00000040341 homo_sapiens ENSP00000428756 82.9825 70.7018 amphilophus_citrinellus ENSACIP00000001006 77.7961 66.2829 ENSG00000040341 homo_sapiens ENSP00000428756 81.2281 68.7719 dicentrarchus_labrax ENSDLAP00005000445 67.0043 56.7294 ENSG00000040341 homo_sapiens ENSP00000428756 80.8772 69.2982 amphiprion_percula ENSAPEP00000031217 69.1154 59.2204 ENSG00000040341 homo_sapiens ENSP00000428756 80.7018 68.4211 oryzias_sinensis ENSOSIP00000032650 63.3609 53.719 ENSG00000040341 homo_sapiens ENSP00000428756 83.3333 77.5439 pelodiscus_sinensis ENSPSIP00000003900 81.4751 75.8148 ENSG00000040341 homo_sapiens ENSP00000428756 90.5263 83.8596 gopherus_evgoodei ENSGEVP00005003511 75.549 69.9854 ENSG00000040341 homo_sapiens ENSP00000428756 83.5088 77.5439 chelonoidis_abingdonii ENSCABP00000010006 88.3117 82.0037 ENSG00000040341 homo_sapiens ENSP00000428756 80.8772 69.2982 seriola_dumerili ENSSDUP00000017191 68.9088 59.0433 ENSG00000040341 homo_sapiens ENSP00000428756 77.0175 65.9649 cottoperca_gobio ENSCGOP00000030320 69.5721 59.588 ENSG00000040341 homo_sapiens ENSP00000428756 92.4561 85.7895 struthio_camelus_australis ENSSCUP00000021488 77.5 71.9118 ENSG00000040341 homo_sapiens ENSP00000428756 92.4561 85.7895 anser_brachyrhynchus ENSABRP00000009769 77.5 71.9118 ENSG00000040341 homo_sapiens ENSP00000428756 83.3333 70.3509 gasterosteus_aculeatus ENSGACP00000003611 77.2358 65.2033 ENSG00000040341 homo_sapiens ENSP00000428756 74.2105 63.6842 cynoglossus_semilaevis ENSCSEP00000015682 63.8973 54.8338 ENSG00000040341 homo_sapiens ENSP00000428756 80 68.4211 poecilia_formosa ENSPFOP00000013230 67.8571 58.0357 ENSG00000040341 homo_sapiens ENSP00000428756 81.0526 69.6491 myripristis_murdjan ENSMMDP00005040408 69.2654 59.5202 ENSG00000040341 homo_sapiens ENSP00000428756 82.1053 69.2982 sander_lucioperca ENSSLUP00000034528 67.0487 56.5903 ENSG00000040341 homo_sapiens ENSP00000428756 92.4561 85.4386 strigops_habroptila ENSSHBP00005008509 77.5 71.6176 ENSG00000040341 homo_sapiens ENSP00000428756 80.8772 69.2982 amphiprion_ocellaris ENSAOCP00000009237 69.1154 59.2204 ENSG00000040341 homo_sapiens ENSP00000428756 92.1053 85.2632 terrapene_carolina_triunguis ENSTMTP00000007430 75.1073 69.5279 ENSG00000040341 homo_sapiens ENSP00000428756 11.0526 9.29825 hucho_hucho ENSHHUP00000026249 80.7692 67.9487 ENSG00000040341 homo_sapiens ENSP00000428756 16.3158 13.6842 hucho_hucho ENSHHUP00000017674 81.5789 68.4211 ENSG00000040341 homo_sapiens ENSP00000428756 14.5614 13.1579 hucho_hucho ENSHHUP00000026247 86.4583 78.125 ENSG00000040341 homo_sapiens ENSP00000428756 81.0526 68.4211 betta_splendens ENSBSLP00000034945 68.75 58.0357 ENSG00000040341 homo_sapiens ENSP00000428756 86.1404 74.5614 pygocentrus_nattereri ENSPNAP00000017362 72.8487 63.0564 ENSG00000040341 homo_sapiens ENSP00000428756 80.1754 68.0702 anabas_testudineus ENSATEP00000037049 66.7153 56.6423 ENSG00000040341 homo_sapiens ENSP00000428756 7.7193 3.33333 ciona_savignyi ENSCSAVP00000003266 17.8138 7.69231 ENSG00000040341 homo_sapiens ENSP00000428756 4.21053 2.2807 ciona_savignyi ENSCSAVP00000011529 11.4286 6.19048 ENSG00000040341 homo_sapiens ENSP00000428756 80.8772 69.2982 seriola_lalandi_dorsalis ENSSLDP00000009056 68.9088 59.0433 ENSG00000040341 homo_sapiens ENSP00000428756 81.2281 68.7719 labrus_bergylta ENSLBEP00000018867 68.7964 58.2467 ENSG00000040341 homo_sapiens ENSP00000428756 81.2281 69.2982 pundamilia_nyererei ENSPNYP00000001444 69.4153 59.2204 ENSG00000040341 homo_sapiens ENSP00000428756 80.3509 68.4211 mastacembelus_armatus ENSMAMP00000034282 68.5629 58.3832 ENSG00000040341 homo_sapiens ENSP00000428756 15.0877 13.3333 stegastes_partitus ENSSPAP00000029431 85.1485 75.2475 ENSG00000040341 homo_sapiens ENSP00000428756 81.0526 69.2982 stegastes_partitus ENSSPAP00000000371 69.2654 59.2204 ENSG00000040341 homo_sapiens ENSP00000428756 80.8772 69.2982 acanthochromis_polyacanthus ENSAPOP00000021981 69.1154 59.2204 ENSG00000040341 homo_sapiens ENSP00000428756 92.2807 85.614 aquila_chrysaetos_chrysaetos ENSACCP00020006997 77.3529 71.7647 ENSG00000040341 homo_sapiens ENSP00000428756 80 68.7719 nothobranchius_furzeri ENSNFUP00015026806 68.9864 59.3041 ENSG00000040341 homo_sapiens ENSP00000428756 80.1754 68.4211 cyprinodon_variegatus ENSCVAP00000008137 67.9049 57.9495 ENSG00000040341 homo_sapiens ENSP00000428756 83.6842 72.6316 denticeps_clupeoides ENSDCDP00000054278 69.8389 60.6149 ENSG00000040341 homo_sapiens ENSP00000428756 81.4035 69.1228 larimichthys_crocea ENSLCRP00005022726 69.2537 58.806 ENSG00000040341 homo_sapiens ENSP00000428756 80.3509 68.2456 takifugu_rubripes ENSTRUP00000082690 62.3978 52.9973 ENSG00000040341 homo_sapiens ENSP00000428756 92.2807 85.0877 ficedula_albicollis ENSFALP00000022574 77.3529 71.3235 ENSG00000040341 homo_sapiens ENSP00000428756 80.5263 68.7719 hippocampus_comes ENSHCOP00000003383 68.4054 58.4203 ENSG00000040341 homo_sapiens ENSP00000428756 84.2105 73.1579 cyprinus_carpio_carpio ENSCCRP00000166495 70.6922 61.4138 ENSG00000040341 homo_sapiens ENSP00000428756 85.9649 74.9123 cyprinus_carpio_carpio ENSCCRP00000144604 72.2714 62.9794 ENSG00000040341 homo_sapiens ENSP00000428756 92.2807 85.2632 coturnix_japonica ENSCJPP00005013965 77.3529 71.4706 ENSG00000040341 homo_sapiens ENSP00000428756 42.4561 35.2632 poecilia_latipinna ENSPLAP00000006628 76.3407 63.4069 ENSG00000040341 homo_sapiens ENSP00000428756 41.0526 34.7368 poecilia_latipinna ENSPLAP00000023556 60.3093 51.0309 ENSG00000040341 homo_sapiens ENSP00000428756 79.8246 68.4211 sinocyclocheilus_grahami ENSSGRP00000109229 67.5074 57.8635 ENSG00000040341 homo_sapiens ENSP00000428756 86.3158 74.9123 sinocyclocheilus_grahami ENSSGRP00000023460 72.5664 62.9794 ENSG00000040341 homo_sapiens ENSP00000428756 81.2281 69.2982 maylandia_zebra ENSMZEP00005028775 69.4153 59.2204 ENSG00000040341 homo_sapiens ENSP00000428756 73.6842 61.5789 tetraodon_nigroviridis ENSTNIP00000011007 73.9437 61.7958 ENSG00000040341 homo_sapiens ENSP00000428756 75.4386 63.3333 paramormyrops_kingsleyae ENSPKIP00000022805 81.4394 68.3712 ENSG00000040341 homo_sapiens ENSP00000428756 84.0351 72.1053 scleropages_formosus ENSSFOP00015063304 69.521 59.6517 ENSG00000040341 homo_sapiens ENSP00000428756 82.807 71.7544 leptobrachium_leishanense ENSLLEP00000010960 75.52 65.44 ENSG00000040341 homo_sapiens ENSP00000428756 81.0526 69.1228 scophthalmus_maximus ENSSMAP00000056776 64.5251 55.0279 ENSG00000040341 homo_sapiens ENSP00000428756 81.0526 68.9474 oryzias_melastigma ENSOMEP00000009308 69.2654 58.9205
Go ID
Go term
No. evidence
Entries
Species
Category
GO:0003723 enables RNA binding 1 HDA Homo_sapiens(9606) Function GO:0003725 enables double-stranded RNA binding 2 IBA,IDA Homo_sapiens(9606) Function GO:0003729 enables mRNA binding 1 IBA Homo_sapiens(9606) Function GO:0005515 enables protein binding 1 IPI Homo_sapiens(9606) Function GO:0005730 located_in nucleolus 1 IEA Homo_sapiens(9606) Component GO:0005783 located_in endoplasmic reticulum 1 IEA Homo_sapiens(9606) Component GO:0005874 located_in microtubule 1 IEA Homo_sapiens(9606) Component GO:0005886 is_active_in plasma membrane 1 IBA Homo_sapiens(9606) Component GO:0007281 involved_in germ cell development 1 IBA Homo_sapiens(9606) Process GO:0008298 involved_in intracellular mRNA localization 1 IBA Homo_sapiens(9606) Process GO:0010494 is_active_in cytoplasmic stress granule 1 IBA Homo_sapiens(9606) Component GO:0016020 located_in membrane 1 HDA Homo_sapiens(9606) Component GO:0019894 enables kinesin binding 1 IEA Homo_sapiens(9606) Function GO:0030424 located_in axon 1 IEA Homo_sapiens(9606) Component GO:0030544 enables Hsp70 protein binding 1 IEA Homo_sapiens(9606) Function GO:0031965 located_in nuclear membrane 1 IEA Homo_sapiens(9606) Component GO:0032839 located_in dendrite cytoplasm 1 IEA Homo_sapiens(9606) Component GO:0032956 involved_in regulation of actin cytoskeleton organization 1 IEA Homo_sapiens(9606) Process GO:0034599 involved_in cellular response to oxidative stress 1 IEA Homo_sapiens(9606) Process GO:0035418 involved_in protein localization to synapse 1 IBA Homo_sapiens(9606) Process GO:0043005 is_active_in neuron projection 1 IBA Homo_sapiens(9606) Component GO:0043022 enables ribosome binding 1 IEA Homo_sapiens(9606) Function GO:0043025 is_active_in neuronal cell body 1 IBA Homo_sapiens(9606) Component GO:0043198 located_in dendritic shaft 1 IEA Homo_sapiens(9606) Component GO:0048592 involved_in eye morphogenesis 1 IEA Homo_sapiens(9606) Process GO:0051019 enables mitogen-activated protein kinase binding 1 IEA Homo_sapiens(9606) Function GO:0051489 involved_in regulation of filopodium assembly 1 IEA Homo_sapiens(9606) Process GO:0051965 involved_in positive regulation of synapse assembly 1 IEA Homo_sapiens(9606) Process GO:0061003 involved_in positive regulation of dendritic spine morphogenesis 1 IEA Homo_sapiens(9606) Process GO:0098964 involved_in anterograde dendritic transport of messenger ribonucleoprotein complex 1 IBA Homo_sapiens(9606) Process GO:1900454 involved_in positive regulation of long-term synaptic depression 1 IEA Homo_sapiens(9606) Process GO:1990124 part_of messenger ribonucleoprotein complex 1 IBA Homo_sapiens(9606) Component
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