Ensembl ID
ENSG00000040341
Gene ID
27067
Accession
11371
Gene Symbol
STAU2
Alias
39K2;39K3
Full Name
staufen double-stranded RNA binding protein 2
Position
8 : 73420369 - 73747708
Length
327340 bases
Strand
Minus strand
Status
Confidence
Main interacting RNAs mRNA RBP type
Canonical_RBPs
Summary
Staufen homolog 2 is a member of the family of double-stranded RNA (dsRNA)-binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles. These proteins are characterized by the presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary structures. Staufen homolog 2 shares 48.5% and 59.9% similarity with drosophila and human staufen, respectively. The exact function of Staufen homolog 2 is not known, but since it contains 3 copies of conserved dsRNA binding domain, it could be involved in double-stranded RNA binding events. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2009]
ENSG00000040341 Expression In 33 Tumors
Ensembl ID
Gene symbol
Log2 Foldchange
Pvaue
Cancer
ENSG00000040341
STAU2
-0.4
3.43e-17
KIRC
ENSG00000040341
STAU2
-0.9
2.10e-20
HNSC
ENSG00000040341
STAU2
0.52
2.05e-14
BRCA
ENSG00000040341
STAU2
-1.4
3.30e-19
GBM
ENSG00000040341
STAU2
0.73
7.22e-16
LUAD
Ensembl ID
Gene symbol
Cancer types
Pubmed ID
Ensembl ID
Gene symbol
Disease/phenotype
Mutation type
Mutated / Total samples
Literature
Ensembl ID
Gene symbol
Cancer
P-value
Which worse
show
ENSG00000040341
STAU2
SARC
0.017
high
show
ENSG00000040341
STAU2
PAAD
0.029
high
show
ENSG00000040341
STAU2
UCEC
0.0093
high
show
ENSG00000040341
STAU2
THCA
0.0045
high
show
ENSG00000040341
STAU2
LGG
0.038
high
show
ENSG00000040341
STAU2
READ
0.045
low
show
ENSG00000040341
STAU2
LUAD
0.04
low
show
ENSG00000040341
STAU2
PCPG
0.0023
high
show
ENSG00000040341
STAU2
THYM
0.00093
low
show
ENSG00000040341
STAU2
BRCA
0.033
high
show
ENSG00000040341
STAU2
COAD
0.0013
low
show
ENSG00000040341
STAU2
OV
0.02
high
show
ENSG00000040341
STAU2
KIRC
0.00031
low
show
ENSG00000040341
STAU2
SKCM
0.016
low
show
ENSG00000040341
STAU2
LIHC
0.0083
high
show
Ensembl ID
Gene symbol
Cancer
CNV type
-log10(q-value)
G-score
average amplitude
frequency
ENSG00000040341
STAU2
LUAD
Amp
1.578842
0.139876
0.631936
0.523256
ENSG00000040341
STAU2
READ
Amp
1.754878
0.178166
0.812660
0.593939
ENSG00000040341
STAU2
COAD
Amp
1.087099
0.075661
0.744521
0.543237
ENSG00000040341
STAU2
LIHC
Amp
1.361709
0.131088
1.114593
0.556757
ENSG00000040341
STAU2
TGCT
Amp
2.222546
0.187750
0.557162
0.820000
ENSG00000040341
STAU2
BLCA
Amp
0.720169
0.164533
0.612689
0.566176
ENSG00000040341
STAU2
BRCA
Amp
5.860526
0.221933
0.935402
0.561111
ENSG00000040341
STAU2
STAD
Amp
0.888214
0.137115
0.585124
0.591837
ENSG00000040341
STAU2
PRAD
Amp
2.393465
0.068974
0.737310
0.306911
ENSG00000040341
STAU2
UCEC
Amp
1.470785
0.121923
0.790458
0.326531
ENSG00000040341
STAU2
UVM
Amp
4.025953
0.353762
1.441062
0.662500
ENSG00000040341
STAU2
OV
Amp
0.672508
0.325578
0.822082
0.523316
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