RBP Type	Canonical_RBPs
Diseases	Cancer Disease
Drug	N.A.
Main interacting RNAs	tRNA
Moonlighting functions	N.A.
Localizations	N.A.
BulkPerturb-seq	N.A.

Ensembl ID	ENSG00000011376	Gene ID	23395	Accession	17095
Symbol	LARS2	Alias	HLASA;LEURS;PRLTS4;mtLeuRS	Full Name	leucyl-tRNA synthetase 2, mitochondrial
Status	Confidence	Length	166166 bases	Strand	Plus strand
Position	3 : 45388561 - 45554726	RNA binding domain	tRNA-synt_1g , tRNA-synt_1 , Anticodon_1
Summary	This gene encodes a class 1 aminoacyl-tRNA synthetase, mitochondrial leucyl-tRNA synthetase. Each of the twenty aminoacyl-tRNA synthetases catalyzes the aminoacylation of a specific tRNA or tRNA isoaccepting family with the cognate amino acid. [provided by RefSeq, Jul 2008]

Protein	Domain	Pfam ID	E-value	Domain number
ENSP00000495093	tRNA-synt_1g	PF09334	5.7e-29	1
ENSP00000495093	tRNA-synt_1g	PF09334	5.7e-29	2
ENSP00000495093	Anticodon_1	PF08264	1.5e-12	3
ENSP00000495093	tRNA-synt_1	PF00133	4.6e-44	4
ENSP00000495093	tRNA-synt_1	PF00133	4.6e-44	5
ENSP00000495093	tRNA-synt_1	PF00133	4.6e-44	6
ENSP00000495707	tRNA-synt_1g	PF09334	5.7e-29	1
ENSP00000495707	tRNA-synt_1g	PF09334	5.7e-29	2
ENSP00000495707	Anticodon_1	PF08264	1.5e-12	3
ENSP00000495707	tRNA-synt_1	PF00133	4.6e-44	4
ENSP00000495707	tRNA-synt_1	PF00133	4.6e-44	5
ENSP00000495707	tRNA-synt_1	PF00133	4.6e-44	6
ENSP00000498867	tRNA-synt_1g	PF09334	5.7e-29	1
ENSP00000498867	tRNA-synt_1g	PF09334	5.7e-29	2
ENSP00000498867	Anticodon_1	PF08264	1.5e-12	3
ENSP00000498867	tRNA-synt_1	PF00133	4.6e-44	4
ENSP00000498867	tRNA-synt_1	PF00133	4.6e-44	5
ENSP00000498867	tRNA-synt_1	PF00133	4.6e-44	6
ENSP00000265537	tRNA-synt_1g	PF09334	3.1e-21	1
ENSP00000265537	tRNA-synt_1	PF00133	1.6e-32	2
ENSP00000499002	tRNA-synt_1g	PF09334	3.4e-21	1
ENSP00000499002	tRNA-synt_1	PF00133	4.4e-33	2
ENSP00000412893	tRNA-synt_1g	PF09334	2e-16	1
ENSP00000412893	tRNA-synt_1g	PF09334	2e-16	2
ENSP00000412893	Anticodon_1	PF08264	1.4e-12	3
ENSP00000412893	tRNA-synt_1	PF00133	1.8e-30	4
ENSP00000412893	tRNA-synt_1	PF00133	1.8e-30	5
ENSP00000412893	tRNA-synt_1	PF00133	1.8e-30	6
ENSP00000401388	tRNA-synt_1	PF00133	5.4e-05	1

Pubmed ID	Full Name	Cell	Author	Time	Doi

Pubmed ID	Title	Author	Time	Journal
24413189	Human mitochondrial leucyl tRNA synthetase can suppress non cognate pathogenic mt-tRNA mutations.	Tran Hue Hornig-Do	2014-02-01	EMBO molecular medicine
36436798	Lin28a induced mitochondrial dysfunction in human granulosa cells via suppressing LARS2 expression.	Jing Chen	2023-03-01	Cellular signalling

Name	Transcript ID	bp	Protein	Translation ID
LARS2-210	ENST00000650792	10049	903aa	ENSP00000498867
LARS2-202	ENST00000414984	2800	860aa	ENSP00000412893
LARS2-201	ENST00000265537	4169	575aa	ENSP00000265537
LARS2-204	ENST00000431023	1881	No protein	-
LARS2-211	ENST00000651549	3409	596aa	ENSP00000499002
LARS2-209	ENST00000645846	4781	903aa	ENSP00000495093
LARS2-212	ENST00000652135	2752	86aa	ENSP00000499104
LARS2-203	ENST00000430399	566	114aa	ENSP00000401388
LARS2-208	ENST00000642274	4139	903aa	ENSP00000495707
LARS2-205	ENST00000467936	804	No protein	-
LARS2-207	ENST00000485461	580	70aa	ENSP00000494606
LARS2-206	ENST00000474585	567	No protein	-

Pathway ID	Pathway Name	Source

ensgID	Trait	pValue	Pubmed ID

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSG00000011376	homo_sapiens	ENSP00000502585	26.2465	15.0517	homo_sapiens	ENSP00000495093	30.897	17.7187
ENSG00000011376	homo_sapiens	ENSP00000406448	22.5832	12.4406	homo_sapiens	ENSP00000495093	31.5615	17.3865
ENSG00000011376	homo_sapiens	ENSP00000282276	29.511	15.3457	homo_sapiens	ENSP00000495093	19.3798	10.0775
ENSG00000011376	homo_sapiens	ENSP00000262027	22.3333	12.6667	homo_sapiens	ENSP00000495093	22.2591	12.6246
ENSG00000011376	homo_sapiens	ENSP00000377954	23.2993	12.7551	homo_sapiens	ENSP00000495093	30.3433	16.6113
ENSG00000011376	homo_sapiens	ENSP00000364815	23.0222	13.212	homo_sapiens	ENSP00000495093	32.2259	18.4939
ENSG00000011376	homo_sapiens	ENSP00000355889	25.4941	14.8221	homo_sapiens	ENSP00000495093	28.5714	16.6113

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSG00000011376	homo_sapiens	ENSP00000495093	96.2348	95.4596	nomascus_leucogenys	ENSNLEP00000007327	98.5261	97.7324
ENSG00000011376	homo_sapiens	ENSP00000495093	100	99.6678	pan_paniscus	ENSPPAP00000029928	100	99.6678
ENSG00000011376	homo_sapiens	ENSP00000495093	99.557	99.2248	pongo_abelii	ENSPPYP00000015598	99.557	99.2248
ENSG00000011376	homo_sapiens	ENSP00000495093	99.8893	99.6678	pan_troglodytes	ENSPTRP00000025575	99.8893	99.6678
ENSG00000011376	homo_sapiens	ENSP00000495093	99.557	99.2248	gorilla_gorilla	ENSGGOP00000015389	99.557	99.2248
ENSG00000011376	homo_sapiens	ENSP00000495093	88.8151	79.5127	ornithorhynchus_anatinus	ENSOANP00000010850	89.0122	79.6892
ENSG00000011376	homo_sapiens	ENSP00000495093	69.8782	62.68	notamacropus_eugenii	ENSMEUP00000000031	76.4848	68.6061
ENSG00000011376	homo_sapiens	ENSP00000495093	56.4784	53.9313	choloepus_hoffmanni	ENSCHOP00000005596	61.8182	59.0303
ENSG00000011376	homo_sapiens	ENSP00000495093	74.9723	68.9922	dasypus_novemcinctus	ENSDNOP00000027307	91.7344	84.4173
ENSG00000011376	homo_sapiens	ENSP00000495093	66.6667	60.9081	erinaceus_europaeus	ENSEEUP00000008470	79.3149	72.4638
ENSG00000011376	homo_sapiens	ENSP00000495093	72.7575	66.2237	echinops_telfairi	ENSETEP00000015758	72.919	66.3707
ENSG00000011376	homo_sapiens	ENSP00000495093	98.0066	95.5703	callithrix_jacchus	ENSCJAP00000066222	98.1153	95.6763
ENSG00000011376	homo_sapiens	ENSP00000495093	98.4496	96.6777	cercocebus_atys	ENSCATP00000004909	98.4496	96.6777
ENSG00000011376	homo_sapiens	ENSP00000495093	98.7818	97.1207	macaca_fascicularis	ENSMFAP00000033447	98.7818	97.1207
ENSG00000011376	homo_sapiens	ENSP00000495093	94.7951	92.1373	macaca_mulatta	ENSMMUP00000077895	94.2731	91.63
ENSG00000011376	homo_sapiens	ENSP00000495093	98.6711	97.01	macaca_nemestrina	ENSMNEP00000013656	98.6711	97.01
ENSG00000011376	homo_sapiens	ENSP00000495093	98.6711	96.7885	papio_anubis	ENSPANP00000002789	98.6711	96.7885
ENSG00000011376	homo_sapiens	ENSP00000495093	98.5604	96.8992	mandrillus_leucophaeus	ENSMLEP00000018743	98.5604	96.8992
ENSG00000011376	homo_sapiens	ENSP00000495093	86.0465	82.7243	tursiops_truncatus	ENSTTRP00000006449	86.0465	82.7243
ENSG00000011376	homo_sapiens	ENSP00000495093	95.2381	90.6977	vulpes_vulpes	ENSVVUP00000009384	95.2381	90.6977
ENSG00000011376	homo_sapiens	ENSP00000495093	93.0233	86.6002	mus_spretus	MGP_SPRETEiJ_P0094475	93.1264	86.6962
ENSG00000011376	homo_sapiens	ENSP00000495093	92.3588	88.2614	equus_asinus	ENSEASP00005041513	88.6291	84.6971
ENSG00000011376	homo_sapiens	ENSP00000495093	94.7951	89.9225	capra_hircus	ENSCHIP00000001565	94.7951	89.9225
ENSG00000011376	homo_sapiens	ENSP00000495093	93.6877	88.5936	loxodonta_africana	ENSLAFP00000002068	95.4853	90.2935
ENSG00000011376	homo_sapiens	ENSP00000495093	93.4662	89.1473	panthera_leo	ENSPLOP00000002965	93.4662	89.1473
ENSG00000011376	homo_sapiens	ENSP00000495093	94.4629	90.0332	ailuropoda_melanoleuca	ENSAMEP00000012822	94.4629	90.0332
ENSG00000011376	homo_sapiens	ENSP00000495093	93.6877	88.4828	bos_indicus_hybrid	ENSBIXP00005019975	93.6877	88.4828
ENSG00000011376	homo_sapiens	ENSP00000495093	93.4662	87.7076	oryctolagus_cuniculus	ENSOCUP00000030288	90.0747	84.5251
ENSG00000011376	homo_sapiens	ENSP00000495093	93.0233	88.5936	equus_caballus	ENSECAP00000021951	85.4527	81.3835
ENSG00000011376	homo_sapiens	ENSP00000495093	95.0166	90.5869	canis_lupus_familiaris	ENSCAFP00845017936	89.5616	85.3862
ENSG00000011376	homo_sapiens	ENSP00000495093	93.3555	88.9258	panthera_pardus	ENSPPRP00000012258	93.3555	88.9258
ENSG00000011376	homo_sapiens	ENSP00000495093	94.6844	90.4762	marmota_marmota_marmota	ENSMMMP00000009730	94.6844	90.4762
ENSG00000011376	homo_sapiens	ENSP00000495093	95.5703	91.5836	balaenoptera_musculus	ENSBMSP00010026483	95.5703	91.5836
ENSG00000011376	homo_sapiens	ENSP00000495093	90.0332	83.278	cavia_porcellus	ENSCPOP00000007249	90.133	83.3703
ENSG00000011376	homo_sapiens	ENSP00000495093	76.1905	72.2038	felis_catus	ENSFCAP00000058476	79.8144	75.6381
ENSG00000011376	homo_sapiens	ENSP00000495093	94.4629	89.5903	ursus_americanus	ENSUAMP00000004649	94.4629	89.5903
ENSG00000011376	homo_sapiens	ENSP00000495093	90.2547	80.1772	monodelphis_domestica	ENSMODP00000014150	90.2547	80.1772
ENSG00000011376	homo_sapiens	ENSP00000495093	93.7984	88.8151	bison_bison_bison	ENSBBBP00000020051	93.7984	88.8151
ENSG00000011376	homo_sapiens	ENSP00000495093	95.6811	91.8051	monodon_monoceros	ENSMMNP00015028991	95.6811	91.8051
ENSG00000011376	homo_sapiens	ENSP00000495093	94.9059	90.5869	sus_scrofa	ENSSSCP00000073491	95.0111	90.6874
ENSG00000011376	homo_sapiens	ENSP00000495093	96.567	93.0233	microcebus_murinus	ENSMICP00000051700	96.6741	93.1264
ENSG00000011376	homo_sapiens	ENSP00000495093	91.2514	84.1639	octodon_degus	ENSODEP00000013241	91.3525	84.2572
ENSG00000011376	homo_sapiens	ENSP00000495093	94.0199	88.2614	jaculus_jaculus	ENSJJAP00000004817	94.0199	88.2614
ENSG00000011376	homo_sapiens	ENSP00000495093	94.3522	89.9225	ovis_aries_rambouillet	ENSOARP00020033015	94.3522	89.9225
ENSG00000011376	homo_sapiens	ENSP00000495093	94.4629	89.5903	ursus_maritimus	ENSUMAP00000007336	94.4629	89.5903
ENSG00000011376	homo_sapiens	ENSP00000495093	90.2547	83.278	ochotona_princeps	ENSOPRP00000000427	93.3562	86.1397
ENSG00000011376	homo_sapiens	ENSP00000495093	95.6811	92.0266	delphinapterus_leucas	ENSDLEP00000017622	95.6811	92.0266
ENSG00000011376	homo_sapiens	ENSP00000495093	95.0166	91.2514	physeter_catodon	ENSPCTP00005015995	95.0166	91.2514
ENSG00000011376	homo_sapiens	ENSP00000495093	93.0233	86.4895	mus_caroli	MGP_CAROLIEiJ_P0090729	93.1264	86.5854
ENSG00000011376	homo_sapiens	ENSP00000495093	93.0233	86.4895	mus_musculus	ENSMUSP00000036710	93.1264	86.5854
ENSG00000011376	homo_sapiens	ENSP00000495093	86.3787	79.1805	dipodomys_ordii	ENSDORP00000016097	88.0361	80.6998
ENSG00000011376	homo_sapiens	ENSP00000495093	93.6877	88.8151	mustela_putorius_furo	ENSMPUP00000015217	88.7723	84.1553
ENSG00000011376	homo_sapiens	ENSP00000495093	97.8959	95.7918	aotus_nancymaae	ENSANAP00000034111	98.0044	95.898
ENSG00000011376	homo_sapiens	ENSP00000495093	97.8959	95.5703	saimiri_boliviensis_boliviensis	ENSSBOP00000011895	98.0044	95.6763
ENSG00000011376	homo_sapiens	ENSP00000495093	82.1705	78.959	vicugna_pacos	ENSVPAP00000008459	87.9147	84.4787
ENSG00000011376	homo_sapiens	ENSP00000495093	98.2281	96.6777	chlorocebus_sabaeus	ENSCSAP00000012403	98.2281	96.6777
ENSG00000011376	homo_sapiens	ENSP00000495093	66.3344	61.0188	tupaia_belangeri	ENSTBEP00000009321	72.7825	66.9502
ENSG00000011376	homo_sapiens	ENSP00000495093	91.4729	85.7143	mesocricetus_auratus	ENSMAUP00000015430	91.4729	85.7143
ENSG00000011376	homo_sapiens	ENSP00000495093	95.3488	91.6944	phocoena_sinus	ENSPSNP00000018336	95.4545	91.796
ENSG00000011376	homo_sapiens	ENSP00000495093	94.3522	90.3654	camelus_dromedarius	ENSCDRP00005007054	94.3522	90.3654
ENSG00000011376	homo_sapiens	ENSP00000495093	95.4596	92.2481	carlito_syrichta	ENSTSYP00000021160	95.4596	92.2481
ENSG00000011376	homo_sapiens	ENSP00000495093	93.3555	88.8151	panthera_tigris_altaica	ENSPTIP00000014709	93.3555	88.8151
ENSG00000011376	homo_sapiens	ENSP00000495093	93.0233	86.9324	rattus_norvegicus	ENSRNOP00000082486	93.1264	87.0288
ENSG00000011376	homo_sapiens	ENSP00000495093	97.3422	93.577	prolemur_simus	ENSPSMP00000014658	97.3422	93.577
ENSG00000011376	homo_sapiens	ENSP00000495093	94.0199	87.7076	microtus_ochrogaster	ENSMOCP00000021253	94.0199	87.7076
ENSG00000011376	homo_sapiens	ENSP00000495093	51.2735	48.3942	sorex_araneus	ENSSARP00000003782	56.2576	53.0984
ENSG00000011376	homo_sapiens	ENSP00000495093	92.9125	86.8217	peromyscus_maniculatus_bairdii	ENSPEMP00000025620	92.9125	86.8217
ENSG00000011376	homo_sapiens	ENSP00000495093	86.4895	81.6168	bos_mutus	ENSBMUP00000010841	94.6667	89.3333
ENSG00000011376	homo_sapiens	ENSP00000495093	93.0233	86.4895	mus_spicilegus	ENSMSIP00000026178	93.1264	86.5854
ENSG00000011376	homo_sapiens	ENSP00000495093	92.5803	86.711	cricetulus_griseus_chok1gshd	ENSCGRP00001011389	92.5803	86.711
ENSG00000011376	homo_sapiens	ENSP00000495093	90.0332	85.2713	pteropus_vampyrus	ENSPVAP00000016730	90.0332	85.2713
ENSG00000011376	homo_sapiens	ENSP00000495093	91.6944	85.825	myotis_lucifugus	ENSMLUP00000009434	91.6944	85.825
ENSG00000011376	homo_sapiens	ENSP00000495093	88.7043	78.6268	vombatus_ursinus	ENSVURP00010028505	88.7043	78.6268
ENSG00000011376	homo_sapiens	ENSP00000495093	95.0166	90.0332	rhinolophus_ferrumequinum	ENSRFEP00010016660	95.1219	90.133
ENSG00000011376	homo_sapiens	ENSP00000495093	92.0266	86.9324	neovison_vison	ENSNVIP00000027471	93.5811	88.4009
ENSG00000011376	homo_sapiens	ENSP00000495093	93.9092	88.7043	bos_taurus	ENSBTAP00000052354	93.9092	88.7043
ENSG00000011376	homo_sapiens	ENSP00000495093	74.8616	67.5526	heterocephalus_glaber_female	ENSHGLP00000036313	78.6047	70.9302
ENSG00000011376	homo_sapiens	ENSP00000495093	99.0033	97.2315	rhinopithecus_bieti	ENSRBIP00000029725	99.0033	97.2315
ENSG00000011376	homo_sapiens	ENSP00000495093	95.0166	90.5869	canis_lupus_dingo	ENSCAFP00020016629	95.0166	90.5869
ENSG00000011376	homo_sapiens	ENSP00000495093	95.0166	90.6977	sciurus_vulgaris	ENSSVLP00005019001	95.0166	90.6977
ENSG00000011376	homo_sapiens	ENSP00000495093	88.4828	78.2946	phascolarctos_cinereus	ENSPCIP00000033914	88.9755	78.7305
ENSG00000011376	homo_sapiens	ENSP00000495093	89.8117	84.4961	procavia_capensis	ENSPCAP00000003621	90.0111	84.6837
ENSG00000011376	homo_sapiens	ENSP00000495093	93.2447	86.9324	nannospalax_galili	ENSNGAP00000008480	93.1416	86.8363
ENSG00000011376	homo_sapiens	ENSP00000495093	94.2414	88.9258	bos_grunniens	ENSBGRP00000013561	94.2414	88.9258
ENSG00000011376	homo_sapiens	ENSP00000495093	85.1606	79.1805	chinchilla_lanigera	ENSCLAP00000022235	90.8983	84.5154
ENSG00000011376	homo_sapiens	ENSP00000495093	92.4695	87.5969	cervus_hanglu_yarkandensis	ENSCHYP00000032085	92.4695	87.5969
ENSG00000011376	homo_sapiens	ENSP00000495093	93.7984	88.7043	catagonus_wagneri	ENSCWAP00000023000	93.9024	88.8027
ENSG00000011376	homo_sapiens	ENSP00000495093	94.9059	90.5869	ictidomys_tridecemlineatus	ENSSTOP00000023929	94.9059	90.5869
ENSG00000011376	homo_sapiens	ENSP00000495093	84.4961	80.9524	otolemur_garnettii	ENSOGAP00000003913	93.6196	89.6933
ENSG00000011376	homo_sapiens	ENSP00000495093	98.0066	95.6811	cebus_imitator	ENSCCAP00000039553	98.1153	95.7871
ENSG00000011376	homo_sapiens	ENSP00000495093	94.7951	89.9225	urocitellus_parryii	ENSUPAP00010019797	94.7951	89.9225
ENSG00000011376	homo_sapiens	ENSP00000495093	94.5736	89.1473	moschus_moschiferus	ENSMMSP00000025145	94.5736	89.1473
ENSG00000011376	homo_sapiens	ENSP00000495093	99.0033	97.1207	rhinopithecus_roxellana	ENSRROP00000040717	99.0033	97.1207
ENSG00000011376	homo_sapiens	ENSP00000495093	93.4662	87.1539	mus_pahari	MGP_PahariEiJ_P0026403	93.5698	87.2506
ENSG00000011376	homo_sapiens	ENSP00000495093	91.9158	89.0365	propithecus_coquereli	ENSPCOP00000030309	96.5116	93.4884
ENSG00000011376	homo_sapiens	ENSP00000495093	50.8306	32.3367	caenorhabditis_elegans	ZK524.3a.1	53.4342	33.993
ENSG00000011376	homo_sapiens	ENSP00000495093	54.4851	40.3101	drosophila_melanogaster	FBpp0073204	56.6168	41.8872
ENSG00000011376	homo_sapiens	ENSP00000495093	59.9114	42.4142	ciona_intestinalis	ENSCINP00000007388	61.3379	43.424
ENSG00000011376	homo_sapiens	ENSP00000495093	57.2536	45.4042	eptatretus_burgeri	ENSEBUP00000008243	68.2959	54.1612
ENSG00000011376	homo_sapiens	ENSP00000495093	79.2913	65.8915	callorhinchus_milii	ENSCMIP00000024202	79.5556	66.1111
ENSG00000011376	homo_sapiens	ENSP00000495093	81.5061	68.1063	latimeria_chalumnae	ENSLACP00000006143	80.7903	67.5082
ENSG00000011376	homo_sapiens	ENSP00000495093	79.1805	66.113	lepisosteus_oculatus	ENSLOCP00000002392	79.1805	66.113
ENSG00000011376	homo_sapiens	ENSP00000495093	78.0731	64.3411	clupea_harengus	ENSCHAP00000019380	78.3333	64.5556
ENSG00000011376	homo_sapiens	ENSP00000495093	72.6467	59.4684	danio_rerio	ENSDARP00000099569	78.5629	64.3114
ENSG00000011376	homo_sapiens	ENSP00000495093	77.6301	62.7907	carassius_auratus	ENSCARP00000040430	76.1129	61.5635
ENSG00000011376	homo_sapiens	ENSP00000495093	73.3112	59.9114	astyanax_mexicanus	ENSAMXP00000011300	77.1562	63.0536
ENSG00000011376	homo_sapiens	ENSP00000495093	78.4053	63.4552	ictalurus_punctatus	ENSIPUP00000030480	78.232	63.3149
ENSG00000011376	homo_sapiens	ENSP00000495093	76.5227	61.0188	esox_lucius	ENSELUP00000046401	75.4367	60.1528
ENSG00000011376	homo_sapiens	ENSP00000495093	77.5194	63.3444	electrophorus_electricus	ENSEEEP00000048985	75.9219	62.039
ENSG00000011376	homo_sapiens	ENSP00000495093	35.9911	26.7996	oncorhynchus_kisutch	ENSOKIP00005008099	65	48.4
ENSG00000011376	homo_sapiens	ENSP00000495093	76.6334	61.794	oncorhynchus_kisutch	ENSOKIP00005027770	75.8772	61.1842
ENSG00000011376	homo_sapiens	ENSP00000495093	50.2769	39.3134	oncorhynchus_mykiss	ENSOMYP00000082287	70.2786	54.9536
ENSG00000011376	homo_sapiens	ENSP00000495093	76.7442	62.237	oncorhynchus_mykiss	ENSOMYP00000003443	75.8206	61.488
ENSG00000011376	homo_sapiens	ENSP00000495093	57.6966	46.5116	salmo_salar	ENSSSAP00000053521	71.1749	57.377
ENSG00000011376	homo_sapiens	ENSP00000495093	76.7442	62.0155	salmo_salar	ENSSSAP00000082275	75.9868	61.4035
ENSG00000011376	homo_sapiens	ENSP00000495093	76.9657	61.9048	salmo_trutta	ENSSTUP00000063115	73.545	59.1534
ENSG00000011376	homo_sapiens	ENSP00000495093	64.5626	52.1595	salmo_trutta	ENSSTUP00000053001	70.6667	57.0909
ENSG00000011376	homo_sapiens	ENSP00000495093	46.7331	37.0986	gadus_morhua	ENSGMOP00000038534	72.8843	57.8584
ENSG00000011376	homo_sapiens	ENSP00000495093	75.6368	61.5725	fundulus_heteroclitus	ENSFHEP00000001055	75.6368	61.5725
ENSG00000011376	homo_sapiens	ENSP00000495093	73.8649	60.2436	poecilia_reticulata	ENSPREP00000013755	74.8597	61.055
ENSG00000011376	homo_sapiens	ENSP00000495093	74.8616	61.1296	xiphophorus_maculatus	ENSXMAP00000010839	74.7788	61.0619
ENSG00000011376	homo_sapiens	ENSP00000495093	76.412	61.2403	oryzias_latipes	ENSORLP00000005750	73.5608	58.9552
ENSG00000011376	homo_sapiens	ENSP00000495093	76.7442	61.9048	cyclopterus_lumpus	ENSCLMP00005018564	76.6593	61.8363
ENSG00000011376	homo_sapiens	ENSP00000495093	77.2979	61.5725	oreochromis_niloticus	ENSONIP00000008584	76.3676	60.8315
ENSG00000011376	homo_sapiens	ENSP00000495093	77.1872	61.6833	haplochromis_burtoni	ENSHBUP00000012228	77.0166	61.547
ENSG00000011376	homo_sapiens	ENSP00000495093	77.2979	61.794	astatotilapia_calliptera	ENSACLP00000019209	77.4695	61.9312
ENSG00000011376	homo_sapiens	ENSP00000495093	77.1872	62.0155	sparus_aurata	ENSSAUP00010033426	75.1888	60.4099
ENSG00000011376	homo_sapiens	ENSP00000495093	77.6301	62.3477	lates_calcarifer	ENSLCAP00010012192	77.5443	62.2788
ENSG00000011376	homo_sapiens	ENSP00000495093	81.0631	68.9922	xenopus_tropicalis	ENSXETP00000077205	81.3333	69.2222
ENSG00000011376	homo_sapiens	ENSP00000495093	76.8549	65.67	chrysemys_picta_bellii	ENSCPBP00000033104	83.4135	71.274
ENSG00000011376	homo_sapiens	ENSP00000495093	81.8383	69.8782	sphenodon_punctatus	ENSSPUP00000003806	81.7478	69.8009
ENSG00000011376	homo_sapiens	ENSP00000495093	84.0532	72.093	crocodylus_porosus	ENSCPRP00005011644	83.9602	72.0133
ENSG00000011376	homo_sapiens	ENSP00000495093	80.7309	67.3311	notechis_scutatus	ENSNSUP00000009426	80.6416	67.2566
ENSG00000011376	homo_sapiens	ENSP00000495093	77.6301	64.5626	pseudonaja_textilis	ENSPTXP00000018454	77.8024	64.7059
ENSG00000011376	homo_sapiens	ENSP00000495093	83.4994	71.7608	anas_platyrhynchos_platyrhynchos	ENSAPLP00000021306	79.8729	68.6441
ENSG00000011376	homo_sapiens	ENSP00000495093	82.9457	71.3178	gallus_gallus	ENSGALP00010024923	81.9475	70.4595
ENSG00000011376	homo_sapiens	ENSP00000495093	83.8317	71.9823	meleagris_gallopavo	ENSMGAP00000021082	80.7898	69.3703
ENSG00000011376	homo_sapiens	ENSP00000495093	84.9391	72.8682	serinus_canaria	ENSSCAP00000002663	84.8451	72.7876
ENSG00000011376	homo_sapiens	ENSP00000495093	84.9391	72.3145	parus_major	ENSPMJP00000014112	84.8451	72.2345
ENSG00000011376	homo_sapiens	ENSP00000495093	76.3012	64.4518	anolis_carolinensis	ENSACAP00000014448	84.4363	71.3235
ENSG00000011376	homo_sapiens	ENSP00000495093	74.8616	59.4684	neolamprologus_brichardi	ENSNBRP00000029123	77.081	61.2315
ENSG00000011376	homo_sapiens	ENSP00000495093	77.2979	63.8981	naja_naja	ENSNNAP00000013433	79.4989	65.7175
ENSG00000011376	homo_sapiens	ENSP00000495093	82.6135	70.2104	podarcis_muralis	ENSPMRP00000025929	82.5221	70.1327
ENSG00000011376	homo_sapiens	ENSP00000495093	84.9391	73.3112	geospiza_fortis	ENSGFOP00000022217	84.8451	73.2301
ENSG00000011376	homo_sapiens	ENSP00000495093	84.7176	72.979	taeniopygia_guttata	ENSTGUP00000025610	84.7176	72.979
ENSG00000011376	homo_sapiens	ENSP00000495093	77.7409	65.7807	erpetoichthys_calabaricus	ENSECRP00000019666	77.0582	65.2031
ENSG00000011376	homo_sapiens	ENSP00000495093	75.526	61.3511	kryptolebias_marmoratus	ENSKMAP00000028165	75.4425	61.2832
ENSG00000011376	homo_sapiens	ENSP00000495093	80.5094	67.9956	salvator_merianae	ENSSMRP00000013007	79.7149	67.3246
ENSG00000011376	homo_sapiens	ENSP00000495093	76.3012	61.5725	oryzias_javanicus	ENSOJAP00000038540	75.5482	60.9649
ENSG00000011376	homo_sapiens	ENSP00000495093	76.9657	62.5692	amphilophus_citrinellus	ENSACIP00000014039	77.8275	63.2699
ENSG00000011376	homo_sapiens	ENSP00000495093	76.9657	62.0155	dicentrarchus_labrax	ENSDLAP00005010413	76.8805	61.9469
ENSG00000011376	homo_sapiens	ENSP00000495093	74.9723	60.5759	amphiprion_percula	ENSAPEP00000027248	76.4972	61.8079
ENSG00000011376	homo_sapiens	ENSP00000495093	56.6999	45.6257	oryzias_sinensis	ENSOSIP00000000599	74.6356	60.0583
ENSG00000011376	homo_sapiens	ENSP00000495093	66.3344	56.1462	pelodiscus_sinensis	ENSPSIP00000018876	85.4494	72.3252
ENSG00000011376	homo_sapiens	ENSP00000495093	19.7121	17.7187	pelodiscus_sinensis	ENSPSIP00000013030	86.4078	77.6699
ENSG00000011376	homo_sapiens	ENSP00000495093	84.9391	73.6434	gopherus_evgoodei	ENSGEVP00005005843	85.1276	73.8069
ENSG00000011376	homo_sapiens	ENSP00000495093	85.0498	73.4219	chelonoidis_abingdonii	ENSCABP00000015901	85.2386	73.5849
ENSG00000011376	homo_sapiens	ENSP00000495093	76.5227	61.1296	seriola_dumerili	ENSSDUP00000023006	76.5227	61.1296
ENSG00000011376	homo_sapiens	ENSP00000495093	76.3012	60.9081	cottoperca_gobio	ENSCGOP00000020660	76.2168	60.8407
ENSG00000011376	homo_sapiens	ENSP00000495093	84.4961	72.536	struthio_camelus_australis	ENSSCUP00000019094	84.4027	72.4557
ENSG00000011376	homo_sapiens	ENSP00000495093	72.2038	59.3577	anser_brachyrhynchus	ENSABRP00000012441	80.7931	66.4188
ENSG00000011376	homo_sapiens	ENSP00000495093	75.8583	60.7973	gasterosteus_aculeatus	ENSGACP00000009435	75.6906	60.663
ENSG00000011376	homo_sapiens	ENSP00000495093	76.3012	62.4585	cynoglossus_semilaevis	ENSCSEP00000008119	76.3012	62.4585
ENSG00000011376	homo_sapiens	ENSP00000495093	56.0354	45.6257	poecilia_formosa	ENSPFOP00000024057	76.435	62.2356
ENSG00000011376	homo_sapiens	ENSP00000495093	78.1838	63.0122	myripristis_murdjan	ENSMMDP00005028833	78.0973	62.9425
ENSG00000011376	homo_sapiens	ENSP00000495093	77.0764	62.4585	sander_lucioperca	ENSSLUP00000018829	76.9911	62.3894
ENSG00000011376	homo_sapiens	ENSP00000495093	85.0498	72.979	strigops_habroptila	ENSSHBP00005003760	84.9557	72.8982
ENSG00000011376	homo_sapiens	ENSP00000495093	77.4086	62.4585	amphiprion_ocellaris	ENSAOCP00000028915	77.323	62.3894
ENSG00000011376	homo_sapiens	ENSP00000495093	85.7143	74.1971	terrapene_carolina_triunguis	ENSTMTP00000028937	85.9045	74.3618
ENSG00000011376	homo_sapiens	ENSP00000495093	85.6035	74.0864	terrapene_carolina_triunguis	ENSTMTP00000025257	85.7936	74.2508
ENSG00000011376	homo_sapiens	ENSP00000495093	42.7464	34.9945	hucho_hucho	ENSHHUP00000089443	72.8302	59.6226
ENSG00000011376	homo_sapiens	ENSP00000495093	76.8549	62.237	hucho_hucho	ENSHHUP00000084181	75.1896	60.8884
ENSG00000011376	homo_sapiens	ENSP00000495093	73.0897	59.1362	betta_splendens	ENSBSLP00000048857	69.7674	56.4482
ENSG00000011376	homo_sapiens	ENSP00000495093	78.8483	64.4518	pygocentrus_nattereri	ENSPNAP00000015758	78.674	64.3094
ENSG00000011376	homo_sapiens	ENSP00000495093	76.6334	62.0155	anabas_testudineus	ENSATEP00000034694	76.5487	61.9469
ENSG00000011376	homo_sapiens	ENSP00000495093	16.3898	10.4097	ciona_savignyi	ENSCSAVP00000006037	56.0606	35.6061
ENSG00000011376	homo_sapiens	ENSP00000495093	12.9568	10.4097	ciona_savignyi	ENSCSAVP00000006064	66.8571	53.7143
ENSG00000011376	homo_sapiens	ENSP00000495093	52.7132	36.5448	saccharomyces_cerevisiae	YLR382C	53.2438	36.9128
ENSG00000011376	homo_sapiens	ENSP00000495093	76.8549	61.2403	seriola_lalandi_dorsalis	ENSSLDP00000021770	76.7699	61.1726
ENSG00000011376	homo_sapiens	ENSP00000495093	76.1905	62.1262	labrus_bergylta	ENSLBEP00000008547	76.6147	62.4722
ENSG00000011376	homo_sapiens	ENSP00000495093	77.1872	61.794	pundamilia_nyererei	ENSPNYP00000006345	77.3585	61.9312
ENSG00000011376	homo_sapiens	ENSP00000495093	76.5227	61.6833	mastacembelus_armatus	ENSMAMP00000035694	75.7675	61.0746
ENSG00000011376	homo_sapiens	ENSP00000495093	42.7464	34.33	stegastes_partitus	ENSSPAP00000017607	76.4356	61.3861
ENSG00000011376	homo_sapiens	ENSP00000495093	67.4419	54.4851	stegastes_partitus	ENSSPAP00000029934	73.462	59.3486
ENSG00000011376	homo_sapiens	ENSP00000495093	57.2536	43.0786	oncorhynchus_tshawytscha	ENSOTSP00005089601	69.396	52.2148
ENSG00000011376	homo_sapiens	ENSP00000495093	58.361	45.1827	oncorhynchus_tshawytscha	ENSOTSP00005082749	70.0798	54.2553
ENSG00000011376	homo_sapiens	ENSP00000495093	77.2979	62.5692	acanthochromis_polyacanthus	ENSAPOP00000003258	77.2124	62.5
ENSG00000011376	homo_sapiens	ENSP00000495093	85.0498	72.8682	aquila_chrysaetos_chrysaetos	ENSACCP00020004385	84.0263	71.9912
ENSG00000011376	homo_sapiens	ENSP00000495093	76.5227	61.6833	nothobranchius_furzeri	ENSNFUP00015046780	74.3011	59.8925
ENSG00000011376	homo_sapiens	ENSP00000495093	76.412	62.7907	cyprinodon_variegatus	ENSCVAP00000016799	76.3274	62.7212
ENSG00000011376	homo_sapiens	ENSP00000495093	77.6301	64.784	denticeps_clupeoides	ENSDCDP00000001468	78.4116	65.4362
ENSG00000011376	homo_sapiens	ENSP00000495093	76.8549	62.3477	larimichthys_crocea	ENSLCRP00005015131	76.516	62.0728
ENSG00000011376	homo_sapiens	ENSP00000495093	76.5227	61.4618	takifugu_rubripes	ENSTRUP00000086056	74.9458	60.1952
ENSG00000011376	homo_sapiens	ENSP00000495093	84.9391	72.7575	ficedula_albicollis	ENSFALP00000002726	84.8451	72.677
ENSG00000011376	homo_sapiens	ENSP00000495093	73.0897	59.5792	hippocampus_comes	ENSHCOP00000009437	72.6872	59.2511
ENSG00000011376	homo_sapiens	ENSP00000495093	77.4086	63.0122	cyprinus_carpio_carpio	ENSCCRP00000055288	78.2755	63.7178
ENSG00000011376	homo_sapiens	ENSP00000495093	83.6102	71.6501	coturnix_japonica	ENSCJPP00005004387	82.876	71.0209
ENSG00000011376	homo_sapiens	ENSP00000495093	74.8616	60.7973	poecilia_latipinna	ENSPLAP00000017286	74.7788	60.7301
ENSG00000011376	homo_sapiens	ENSP00000495093	67.2204	53.5991	sinocyclocheilus_grahami	ENSSGRP00000018843	73.665	58.7379
ENSG00000011376	homo_sapiens	ENSP00000495093	76.9657	61.6833	maylandia_zebra	ENSMZEP00005018094	77.1365	61.8202
ENSG00000011376	homo_sapiens	ENSP00000495093	71.5393	58.4718	tetraodon_nigroviridis	ENSTNIP00000012524	78.4933	64.1555
ENSG00000011376	homo_sapiens	ENSP00000495093	76.6334	62.7907	paramormyrops_kingsleyae	ENSPKIP00000007698	77.3184	63.352
ENSG00000011376	homo_sapiens	ENSP00000495093	75.8583	61.794	scleropages_formosus	ENSSFOP00015051682	72.8723	59.3617
ENSG00000011376	homo_sapiens	ENSP00000495093	79.9557	67.1096	leptobrachium_leishanense	ENSLLEP00000039923	78.4783	65.8696
ENSG00000011376	homo_sapiens	ENSP00000495093	77.0764	62.0155	scophthalmus_maximus	ENSSMAP00000003780	76.9911	61.9469
ENSG00000011376	homo_sapiens	ENSP00000495093	76.6334	61.9048	oryzias_melastigma	ENSOMEP00000010200	76.8036	62.0422

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0002161	enables aminoacyl-tRNA editing activity	1	IEA	Homo_sapiens(9606)	Function
GO:0004823	enables leucine-tRNA ligase activity	3	IBA,IDA,TAS	Homo_sapiens(9606)	Function
GO:0005524	enables ATP binding	1	IEA	Homo_sapiens(9606)	Function
GO:0005739	is_active_in mitochondrion	1	IBA	Homo_sapiens(9606)	Component
GO:0005759	located_in mitochondrial matrix	1	TAS	Homo_sapiens(9606)	Component
GO:0006418	involved_in tRNA aminoacylation for protein translation	1	TAS	Homo_sapiens(9606)	Process
GO:0006429	involved_in leucyl-tRNA aminoacylation	2	IBA,IDA	Homo_sapiens(9606)	Process
GO:0032543	involved_in mitochondrial translation	1	IBA	Homo_sapiens(9606)	Process
GO:0106074	involved_in aminoacyl-tRNA metabolism involved in translational fidelity	1	IEA	Homo_sapiens(9606)	Process