Ensembl ID ENSG00000011376 Gene ID 23395 Accession 17095
Gene Symbol LARS2 Alias HLASA;LEURS;PRLTS4;mtLeuRS Full Name leucyl-tRNA synthetase 2, mitochondrial
Position 3 : 45388561 - 45554726 Length 166166 bases Strand Plus strand
Status Confidence Main interacting RNAstRNARBP type Canonical_RBPs
Summary This gene encodes a class 1 aminoacyl-tRNA synthetase, mitochondrial leucyl-tRNA synthetase. Each of the twenty aminoacyl-tRNA synthetases catalyzes the aminoacylation of a specific tRNA or tRNA isoaccepting family with the cognate amino acid. [provided by RefSeq, Jul 2008]

ENSG00000011376 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000011376 LARS2 -1.4 3.09e-54 KIRC
ENSG00000011376 LARS2 0.32 7.24e-13 BRCA
ENSG00000011376 LARS2 1.30 1.58e-20 KICH
ENSG00000011376 LARS2 -1.3 2.67e-16 CHOL
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000011376 LARS2 HNSCC 21563216
ENSG00000011376 LARS2 breast cancer 23506640
ENSG00000011376 LARS2 tumor 27239038
ENSG00000011376 LARS2 tumor 28460460
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000011376 LARS2 SARC 0.0072 high
ENSG00000011376 LARS2 UVM 0.00043 low
ENSG00000011376 LARS2 UCEC 0.02 low
ENSG00000011376 LARS2 ACC 0.05 low
ENSG00000011376 LARS2 READ 0.008 low
ENSG00000011376 LARS2 KIRP 0.00063 low
ENSG00000011376 LARS2 LUAD 0.02 high
ENSG00000011376 LARS2 PCPG 0.0027 low
ENSG00000011376 LARS2 THYM 0.012 low
ENSG00000011376 LARS2 COAD 0.0013 low
ENSG00000011376 LARS2 PRAD 0.037 high
ENSG00000011376 LARS2 SKCM 0.019 high
ENSG00000011376 LARS2 CESC 0.047 high
ENSG00000011376 LARS2 LIHC 0.002 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000011376 LARS2 CHOL Del 1.059383 0.237582 0.628918 0.833333
ENSG00000011376 LARS2 LUSC Del 1.882724 0.081685 0.408203 0.858283
ENSG00000011376 LARS2 LUAD Del 0.844218 0.053293 0.321638 0.474806
ENSG00000011376 LARS2 LGG Del 1.011062 0.042420 0.496421 0.089669
ENSG00000011376 LARS2 BLCA Del 1.083304 0.084118 0.383075 0.240196
ENSG00000011376 LARS2 BRCA Del 18.526318 0.144153 0.449449 0.299074
ENSG00000011376 LARS2 STAD Del 2.891642 0.088871 0.333160 0.324263
ENSG00000011376 LARS2 UCEC Del 0.628932 0.046399 0.484543 0.126160
ENSG00000011376 LARS2 MESO Del 13.522122 0.469148 0.570865 0.459770
ENSG00000011376 LARS2 KIRC Del 46.701081 0.168959 0.516597 0.880682
ENSG00000011376 LARS2 OV Del 0.635706 0.172027 0.470415 0.324698