Welcome to
RBP World!
Functions and Diseases
| RBP Type | Canonical_RBPs |
| Diseases | CancerCHIKVSARS-COV-OC43FlavivirusesHIVIAVRVSARS-COV-2SINVDengueZika |
| Drug | N.A. |
| Main interacting RNAs | mRNA |
| Moonlighting functions | N.A. |
| Localizations | Stress granucleP-body |
| BulkPerturb-seq | DataSet_01_407 DataSet_01_427 |
Description
| Ensembl ID | ENSG00000005007 | Gene ID | 5976 | Accession | 9962 |
| Symbol | UPF1 | Alias | UTF;HUPF1;NORF1;RENT1;smg-2;pNORF1 | Full Name | UPF1 RNA helicase and ATPase |
| Status | Confidence | Length | 36272 bases | Strand | Plus strand |
| Position | 19 : 18831959 - 18868230 | RNA binding domain | ResIII , UPF1_1B_dom , UPF1_Zn_bind | ||
| Summary | This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located only in the cytoplasm. When translation ends, it interacts with the protein that is a functional homolog of yeast Upf2p to trigger mRNA decapping. Use of multiple polyadenylation sites has been noted for this gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014] | ||||
RNA binding domains (RBDs)
| Protein | Domain | Pfam ID | E-value | Domain number |
|---|---|---|---|---|
| ENSP00000262803 | ResIII | PF04851 | 0.0001 | 1 |
| ENSP00000262803 | UPF1_Zn_bind | PF09416 | 9.4e-77 | 2 |
| ENSP00000262803 | UPF1_1B_dom | PF18141 | 5.1e-32 | 3 |
| ENSP00000470142 | ResIII | PF04851 | 0.0001 | 1 |
| ENSP00000470142 | UPF1_Zn_bind | PF09416 | 9.5e-77 | 2 |
| ENSP00000470142 | UPF1_1B_dom | PF18141 | 1.6e-28 | 3 |
| ENSP00000515988 | ResIII | PF04851 | 0.00017 | 1 |
| ENSP00000515988 | UPF1_Zn_bind | PF09416 | 9.3e-77 | 2 |
| ENSP00000515988 | UPF1_1B_dom | PF18141 | 5.1e-32 | 3 |
| ENSP00000515989 | UPF1_Zn_bind | PF09416 | 3.6e-77 | 1 |
| ENSP00000515989 | UPF1_1B_dom | PF18141 | 4.1e-22 | 2 |
| ENSP00000515990 | UPF1_Zn_bind | PF09416 | 8.8e-77 | 1 |
RNA binding proteomes (RBPomes)
| Pubmed ID | Full Name | Cell | Author | Time | Doi |
|---|
Literatures on RNA binding capacity
| Pubmed ID | Title | Author | Time | Journal |
|---|---|---|---|---|
| 10999600 | Characterization of the biochemical properties of the human Upf1 gene product that is involved in nonsense-mediated mRNA decay. | A Bhattacharya | 2000-09-01 | RNA (New York, N.Y.) |
| 26773057 | Mechanism and regulation of the nonsense-mediated decay pathway. | Nele Hug | 2016-02-29 | Nucleic acids research |
| 31699982 | Insights into the assembly and architecture of a Staufen-mediated mRNA decay (SMD)-competent mRNP. | Manjeera Gowravaram | 2019-11-07 | Nature communications |
| 36603024 | Nuclear accumulation of host transcripts during Zika Virus Infection. | E Kristoffer Leon | 2023-01-01 | PLoS pathogens |
| 32017897 | Structure-Mediated RNA Decay by UPF1 and G3BP1. | W Joseph Fischer | 2020-04-02 | Molecular cell |
| 16186820 | CBP80 promotes interaction of Upf1 with Upf2 during nonsense-mediated mRNA decay in mammalian cells. | Nao Hosoda | 2005-10-01 | Nature structural & molecular biology |
| 26656492 | A novel role for CARM1 in promoting nonsense-mediated mRNA decay: potential implications for spinal muscular atrophy. | Gabriel Sanchez | 2016-04-07 | Nucleic acids research |
| 18447580 | Posttranscriptional gene regulation by spatial rearrangement of the 3' untranslated region. | B Andrea Eberle | 2008-04-29 | PLoS biology |
| 29236296 | RNA Decay Factor UPF1 Promotes Protein Decay: A Hidden Talent. | Terra-Dawn TD M | 2018-01-01 | BioEssays : news and reviews in molecular, cellular and developmental biology |
| 29504902 | TERIUS: accurate prediction of lncRNA via high-throughput sequencing data representing RNA-binding protein association. | Seo-Won Choi | 2018-02-19 | BMC bioinformatics |
| 26744779 | Polypyrimidine tract binding protein 1 protects mRNAs from recognition by the nonsense-mediated mRNA decay pathway. | Zhiyun Ge | 2016-01-08 | eLife |
| 28827400 | UPF1 helicase promotes TSN-mediated miRNA decay. | A Reyad Elbarbary | 2017-07-15 | Genes & development |
| 26138914 | Human Upf1 is a highly processive RNA helicase and translocase with RNP remodelling activities. | Francesca Fiorini | 2015-07-03 | Nature communications |
| 28821679 | UPF1 Governs Synaptic Plasticity through Association with a STAU2 RNA Granule. | E Tyson Graber | 2017-09-20 | The Journal of neuroscience : the official journal of the Society for Neuroscience |
| 32635561 | UPF1-Mediated RNA Decay-Danse Macabre in a Cloud. | Daria Lavysh | 2020-07-04 | Biomolecules |
| 35729321 | Blood-derived lncRNAs as biomarkers for cancer diagnosis: the Good, the Bad and the Beauty. | Cedric Badowski | 2022-06-21 | NPJ precision oncology |
| 32326562 | The Complex Relationship between HTLV-1 and Nonsense-Mediated mRNA Decay (NMD). | Léa Prochasson | 2020-04-15 | Pathogens (Basel, Switzerland) |
| 25053839 | A novel phosphorylation-independent interaction between SMG6 and UPF1 is essential for human NMD. | Pamela Nicholson | 2014-08-01 | Nucleic acids research |
| 34019569 | Characterisation of the Semliki Forest Virus-host cell interactome reveals the viral capsid protein as an inhibitor of nonsense-mediated mRNA decay. | Lara Contu | 2021-05-01 | PLoS pathogens |
| 31570513 | HELZ directly interacts with CCR4-NOT and causes decay of bound mRNAs. | Aoife Hanet | 2019-10-01 | Life science alliance |
| 35675814 | AKT constitutes a signal-promoted alternative exon-junction complex that regulates nonsense-mediated mRNA decay. | Hana Cho | 2022-08-04 | Molecular cell |
| 35508167 | Walking a tightrope: The complex balancing act of R-loops in genome stability. | R Joshua Brickner | 2022-06-16 | Molecular cell |
| 30655309 | UPFront and center in RNA decay: UPF1 in nonsense-mediated mRNA decay and beyond. | Ki Yoon Kim | 2019-04-01 | RNA (New York, N.Y.) |
| 30916337 | Integrative transcriptomic analysis suggests new autoregulatory splicing events coupled with nonsense-mediated mRNA decay. | Dmitri Pervouchine | 2019-06-04 | Nucleic acids research |
| 27927164 | The role of nucleotide composition in premature termination codon recognition. | Fouad Zahdeh | 2016-12-07 | BMC bioinformatics |
| 30218034 | UPF1-like helicase grip on nucleic acids dictates processivity. | Joanne Kanaan | 2018-09-14 | Nature communications |
| 31131562 | Nonsense-mediated mRNA decay: The challenge of telling right from wrong in a complex transcriptome. | Aparna Kishor | 2019-11-01 | Wiley interdisciplinary reviews. RNA |
| 29284541 | DotAligner: identification and clustering of RNA structure motifs. | A Martin Smith | 2017-12-28 | Genome biology |
Transcripts
| Name | Transcript ID | bp | Protein | Translation ID |
|---|---|---|---|---|
| UPF1-201 | ENST00000262803 | 5321 | 1118aa | ENSP00000262803 |
| UPF1-214 | ENST00000704676 | 5306 | 1113aa | ENSP00000515988 |
| UPF1-215 | ENST00000704677 | 5328 | 391aa | ENSP00000515989 |
| UPF1-216 | ENST00000704678 | 2055 | 346aa | ENSP00000515990 |
| UPF1-207 | ENST00000599848 | 5311 | 1129aa | ENSP00000470142 |
| UPF1-213 | ENST00000601981 | 4990 | No protein | - |
| UPF1-203 | ENST00000594504 | 3270 | No protein | - |
| UPF1-208 | ENST00000600012 | 501 | No protein | - |
| UPF1-211 | ENST00000600868 | 580 | No protein | - |
| UPF1-205 | ENST00000598209 | 551 | No protein | - |
| UPF1-209 | ENST00000600310 | 750 | No protein | - |
| UPF1-217 | ENST00000704679 | 4634 | No protein | - |
| UPF1-206 | ENST00000598471 | 582 | No protein | - |
| UPF1-212 | ENST00000601689 | 561 | No protein | - |
| UPF1-202 | ENST00000594243 | 683 | No protein | - |
| UPF1-204 | ENST00000596842 | 3825 | No protein | - |
| UPF1-210 | ENST00000600689 | 3084 | No protein | - |
Phenotypes
| ensgID | Trait | pValue | Pubmed ID |
|---|
GWAS
| ensgID | SNP | Chromosome | Position | Trait | PubmedID | Or or BEAT | EFO ID |
|---|
Protein-Protein Interaction (PPI)
Paralogs
| Ensembl ID | Source | Target | ||||||
|---|---|---|---|---|---|---|---|---|
| Species | Protein ID | Perc_pos | Perc_id | Species | Protein ID | Perc_pos | Perc_id | |
| ENSG00000005007 | homo_sapiens | ENSP00000156471 | 18.5859 | 9.62963 | homo_sapiens | ENSP00000262803 | 24.6869 | 12.7907 |
| ENSG00000005007 | homo_sapiens | ENSP00000224140 | 13.2985 | 7.73254 | homo_sapiens | ENSP00000262803 | 31.8426 | 18.5152 |
| ENSG00000005007 | homo_sapiens | ENSP00000276241 | 9.4697 | 4.16667 | homo_sapiens | ENSP00000262803 | 2.23614 | 0.9839 |
| ENSG00000005007 | homo_sapiens | ENSP00000255078 | 26.9889 | 17.1198 | homo_sapiens | ENSP00000262803 | 23.9714 | 15.2057 |
| ENSG00000005007 | homo_sapiens | ENSP00000417401 | 15.9683 | 9.58852 | homo_sapiens | ENSP00000262803 | 37.8354 | 22.7191 |
| ENSG00000005007 | homo_sapiens | ENSP00000351185 | 27.4528 | 14.5283 | homo_sapiens | ENSP00000262803 | 26.0286 | 13.7746 |
| ENSG00000005007 | homo_sapiens | ENSP00000379412 | 15.5892 | 8.55057 | homo_sapiens | ENSP00000262803 | 26.7442 | 14.6691 |
| ENSG00000005007 | homo_sapiens | ENSP00000351524 | 15.139 | 8.59938 | homo_sapiens | ENSP00000262803 | 26.297 | 14.9374 |
| ENSG00000005007 | homo_sapiens | ENSP00000262794 | 22.5434 | 13.9554 | homo_sapiens | ENSP00000262803 | 24.4186 | 15.1163 |
| ENSG00000005007 | homo_sapiens | ENSP00000358659 | 24.4267 | 15.5533 | homo_sapiens | ENSP00000262803 | 21.9141 | 13.9535 |
Orthologs
| Ensembl ID | Source | Target | ||||||
|---|---|---|---|---|---|---|---|---|
| Species | Protein ID | Perc_pos | Perc_id | Species | Protein ID | Perc_pos | Perc_id | |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 87.746 | 87.6565 | nomascus_leucogenys | ENSNLEP00000041591 | 98.494 | 98.3936 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 94.4544 | 94.3649 | pan_paniscus | ENSPPAP00000042672 | 96.3504 | 96.2591 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 100 | 100 | pongo_abelii | ENSPPYP00000010923 | 99.0257 | 99.0257 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 100 | 100 | pan_troglodytes | ENSPTRP00000069011 | 99.0257 | 99.0257 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 93.5599 | 93.5599 | gorilla_gorilla | ENSGGOP00000002572 | 99.241 | 99.241 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 98.0322 | 97.3166 | ornithorhynchus_anatinus | ENSOANP00000007238 | 98.4726 | 97.7538 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 94.0072 | 90.7871 | ornithorhynchus_anatinus | ENSOANP00000051835 | 95.6324 | 92.3567 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 99.1055 | 98.7478 | sarcophilus_harrisii | ENSSHAP00000032501 | 99.1055 | 98.7478 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 70.1252 | 69.4097 | notamacropus_eugenii | ENSMEUP00000012918 | 70.2509 | 69.534 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 100 | 100 | callithrix_jacchus | ENSCJAP00000036494 | 99.0257 | 99.0257 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 94.0072 | 93.8283 | cercocebus_atys | ENSCATP00000034826 | 97.9497 | 97.7633 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 31.3059 | 31.2165 | macaca_fascicularis | ENSMFAP00000037221 | 96.4187 | 96.1432 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 33.0054 | 33.0054 | macaca_fascicularis | ENSMFAP00000037235 | 99.1936 | 99.1936 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 100 | 100 | macaca_mulatta | ENSMMUP00000043788 | 99.0257 | 99.0257 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 100 | 100 | macaca_nemestrina | ENSMNEP00000000047 | 99.0257 | 99.0257 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 100 | 100 | papio_anubis | ENSPANP00000032997 | 99.0257 | 99.0257 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 93.1127 | 93.1127 | mandrillus_leucophaeus | ENSMLEP00000008475 | 98.9544 | 98.9544 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 95.6172 | 95.5277 | tursiops_truncatus | ENSTTRP00000010948 | 96.1331 | 96.0432 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 99.9106 | 99.7317 | vulpes_vulpes | ENSVVUP00000010553 | 99.8213 | 99.6425 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 99.1055 | 98.4794 | mus_spretus | MGP_SPRETEiJ_P0088267 | 98.5765 | 97.9537 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 99.4633 | 99.2844 | equus_asinus | ENSEASP00005009145 | 98.669 | 98.4916 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 99.0161 | 98.8372 | capra_hircus | ENSCHIP00000007632 | 98.3126 | 98.135 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 98.0322 | 97.585 | loxodonta_africana | ENSLAFP00000023305 | 97.0771 | 96.6342 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 99.9106 | 99.6422 | panthera_leo | ENSPLOP00000000736 | 98.8496 | 98.5841 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 99.8211 | 99.6422 | ailuropoda_melanoleuca | ENSAMEP00000012088 | 98.8485 | 98.6714 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 99.4633 | 99.2844 | bos_indicus_hybrid | ENSBIXP00005007580 | 98.669 | 98.4916 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 99.4633 | 99.2844 | equus_caballus | ENSECAP00000057276 | 98.669 | 98.4916 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 99.9106 | 99.6422 | canis_lupus_familiaris | ENSCAFP00845027421 | 98.8496 | 98.5841 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 99.9106 | 99.6422 | panthera_pardus | ENSPPRP00000002368 | 98.8496 | 98.5841 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 88.2826 | 86.4937 | marmota_marmota_marmota | ENSMMMP00000002826 | 91.8994 | 90.0372 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 99.3739 | 99.2844 | balaenoptera_musculus | ENSBMSP00010005595 | 98.5803 | 98.4916 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 97.3166 | 97.0483 | cavia_porcellus | ENSCPOP00000015668 | 98.1064 | 97.8359 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 96.0644 | 94.9911 | felis_catus | ENSFCAP00000058732 | 92.4268 | 91.3941 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 99.8211 | 99.6422 | ursus_americanus | ENSUAMP00000008400 | 99.7319 | 99.5532 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 92.6655 | 92.2182 | monodelphis_domestica | ENSMODP00000040291 | 98.3856 | 97.9107 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 93.1127 | 92.9338 | bison_bison_bison | ENSBBBP00000021865 | 92.1239 | 91.9469 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 99.3739 | 99.2844 | monodon_monoceros | ENSMMNP00015009574 | 98.5803 | 98.4916 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 99.3739 | 99.195 | sus_scrofa | ENSSSCP00000036535 | 98.5803 | 98.4028 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 97.4955 | 97.1377 | microcebus_murinus | ENSMICP00000001513 | 97.4084 | 97.0509 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 97.9428 | 97.8533 | octodon_degus | ENSODEP00000016858 | 98.6487 | 98.5586 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 98.9267 | 98.3005 | jaculus_jaculus | ENSJJAP00000023360 | 98.574 | 97.9501 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 99.4633 | 99.2844 | ovis_aries_rambouillet | ENSOARP00020004358 | 98.669 | 98.4916 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 94.7227 | 93.6494 | ursus_maritimus | ENSUMAP00000009637 | 96.7123 | 95.6164 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 86.136 | 85.2415 | ochotona_princeps | ENSOPRP00000012816 | 93.2236 | 92.2556 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 99.3739 | 99.2844 | delphinapterus_leucas | ENSDLEP00000008365 | 98.5803 | 98.4916 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 99.3739 | 99.2844 | physeter_catodon | ENSPCTP00005027959 | 98.5803 | 98.4916 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 99.1055 | 98.4794 | mus_caroli | MGP_CAROLIEiJ_P0084765 | 98.5765 | 97.9537 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 99.1055 | 98.4794 | mus_musculus | ENSMUSP00000075089 | 98.5765 | 97.9537 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 93.1127 | 91.2343 | dipodomys_ordii | ENSDORP00000027782 | 94.123 | 92.2242 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 99.9106 | 99.7317 | mustela_putorius_furo | ENSMPUP00000015404 | 99.8213 | 99.6425 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 93.6494 | 93.2916 | aotus_nancymaae | ENSANAP00000012377 | 95.8791 | 95.5128 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 94.6333 | 94.3649 | saimiri_boliviensis_boliviensis | ENSSBOP00000013846 | 96.8864 | 96.6117 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 99.9106 | 99.9106 | chlorocebus_sabaeus | ENSCSAP00000001590 | 99.9106 | 99.9106 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 94.5438 | 93.4705 | mesocricetus_auratus | ENSMAUP00000010607 | 95.3971 | 94.3141 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 99.3739 | 99.2844 | phocoena_sinus | ENSPSNP00000002932 | 98.5803 | 98.4916 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 99.3739 | 99.195 | camelus_dromedarius | ENSCDRP00005012630 | 98.5803 | 98.4028 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 92.9338 | 92.7549 | carlito_syrichta | ENSTSYP00000017119 | 92.0283 | 91.8512 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 91.1449 | 90.8766 | panthera_tigris_altaica | ENSPTIP00000008974 | 99.7065 | 99.4129 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 99.1055 | 98.4794 | rattus_norvegicus | ENSRNOP00000075905 | 98.5765 | 97.9537 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 100 | 99.8211 | prolemur_simus | ENSPSMP00000001497 | 99.0257 | 98.8485 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 99.0161 | 98.39 | microtus_ochrogaster | ENSMOCP00000006123 | 98.4875 | 97.8648 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 92.8444 | 92.2182 | peromyscus_maniculatus_bairdii | ENSPEMP00000001379 | 92.3488 | 91.726 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 91.9499 | 91.771 | bos_mutus | ENSBMUP00000020134 | 90.9734 | 90.7965 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 99.1055 | 98.4794 | mus_spicilegus | ENSMSIP00000038476 | 98.5765 | 97.9537 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 99.195 | 98.5689 | cricetulus_griseus_chok1gshd | ENSCGRP00001022573 | 99.6406 | 99.0117 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 68.1574 | 68.068 | pteropus_vampyrus | ENSPVAP00000003004 | 68.0965 | 68.0071 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 99.2844 | 98.9267 | myotis_lucifugus | ENSMLUP00000011055 | 99.2844 | 98.9267 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 99.1055 | 98.6583 | vombatus_ursinus | ENSVURP00010019905 | 98.1399 | 97.6971 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 97.4955 | 96.3327 | rhinolophus_ferrumequinum | ENSRFEP00010031518 | 93.2421 | 92.13 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 99.9106 | 99.7317 | neovison_vison | ENSNVIP00000025712 | 99.8213 | 99.6425 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 99.4633 | 99.2844 | bos_taurus | ENSBTAP00000027868 | 98.669 | 98.4916 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 96.8694 | 96.3327 | heterocephalus_glaber_female | ENSHGLP00000015240 | 94.5852 | 94.0611 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 91.9499 | 91.5027 | rhinopithecus_bieti | ENSRBIP00000003024 | 96.2547 | 95.7865 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 99.9106 | 99.7317 | canis_lupus_dingo | ENSCAFP00020015362 | 99.8213 | 99.6425 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 99.7317 | 99.4633 | sciurus_vulgaris | ENSSVLP00005020593 | 98.76 | 98.4942 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 92.576 | 92.1288 | phascolarctos_cinereus | ENSPCIP00000007258 | 98.4776 | 98.0019 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 70.3041 | 70.1252 | procavia_capensis | ENSPCAP00000012158 | 70.4933 | 70.3139 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 99.195 | 98.6583 | nannospalax_galili | ENSNGAP00000026472 | 98.4028 | 97.8705 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 99.4633 | 99.2844 | bos_grunniens | ENSBGRP00000001520 | 98.669 | 98.4916 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 95.2594 | 94.6333 | chinchilla_lanigera | ENSCLAP00000005692 | 94.5826 | 93.9609 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 99.4633 | 99.2844 | cervus_hanglu_yarkandensis | ENSCHYP00000023500 | 98.669 | 98.4916 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 99.4633 | 99.2844 | catagonus_wagneri | ENSCWAP00000025669 | 98.669 | 98.4916 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 99.8211 | 99.6422 | ictidomys_tridecemlineatus | ENSSTOP00000030217 | 96.875 | 96.7014 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 100 | 99.9106 | otolemur_garnettii | ENSOGAP00000011534 | 100 | 99.9106 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 98.0322 | 97.4955 | cebus_imitator | ENSCCAP00000028528 | 95.2215 | 94.7003 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 99.8211 | 99.7317 | urocitellus_parryii | ENSUPAP00010023106 | 99.8211 | 99.7317 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 99.4633 | 99.195 | moschus_moschiferus | ENSMMSP00000030114 | 98.669 | 98.4028 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 94.4544 | 94.2755 | rhinopithecus_roxellana | ENSRROP00000034798 | 97.8684 | 97.683 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 99.1055 | 98.4794 | mus_pahari | MGP_PahariEiJ_P0047646 | 98.5765 | 97.9537 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 99.6422 | 99.4633 | propithecus_coquereli | ENSPCOP00000023360 | 98.6714 | 98.4942 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 64.3113 | 48.4794 | caenorhabditis_elegans | Y48G8AL.6.1 | 67.2591 | 50.7016 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 77.102 | 66.1896 | drosophila_melanogaster | FBpp0073433 | 73.0508 | 62.7119 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 67.0841 | 60.8229 | ciona_intestinalis | ENSCINP00000031943 | 89.7129 | 81.3397 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 92.3077 | 87.3882 | petromyzon_marinus | ENSPMAP00000001338 | 93.3092 | 88.3363 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 15.9213 | 15.2952 | eptatretus_burgeri | ENSEBUP00000012718 | 89 | 85.5 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 51.1628 | 48.0322 | eptatretus_burgeri | ENSEBUP00000016049 | 91.8138 | 86.1958 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 91.771 | 90.3399 | callorhinchus_milii | ENSCMIP00000012225 | 96.1574 | 94.6579 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 61.2701 | 60.644 | latimeria_chalumnae | ENSLACP00000009617 | 98.2783 | 97.274 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 96.3327 | 95.1699 | lepisosteus_oculatus | ENSLOCP00000002426 | 97.9091 | 96.7273 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 95.3488 | 93.4705 | clupea_harengus | ENSCHAP00000025229 | 95.9496 | 94.0594 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 94.9911 | 92.6655 | clupea_harengus | ENSCHAP00000040423 | 95.4178 | 93.0818 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 95.6172 | 93.5599 | danio_rerio | ENSDARP00000153550 | 97.1818 | 95.0909 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 95.6172 | 93.6494 | carassius_auratus | ENSCARP00000085195 | 97.1818 | 95.1818 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 95.5277 | 93.2916 | carassius_auratus | ENSCARP00000025658 | 96.5642 | 94.3038 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 95.2594 | 92.9338 | carassius_auratus | ENSCARP00000022002 | 96.1191 | 93.7726 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 95.6172 | 93.6494 | carassius_auratus | ENSCARP00000002677 | 97.1818 | 95.1818 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 95.7066 | 93.7388 | astyanax_mexicanus | ENSAMXP00000051219 | 97.2727 | 95.2727 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 95.8855 | 94.0966 | ictalurus_punctatus | ENSIPUP00000007528 | 97.4545 | 95.6364 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 94.0072 | 91.4132 | esox_lucius | ENSELUP00000040396 | 93.1738 | 90.6028 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 94.8122 | 92.4866 | esox_lucius | ENSELUP00000034330 | 95.4955 | 93.1532 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 94.6333 | 92.6655 | electrophorus_electricus | ENSEEEP00000000105 | 96.4448 | 94.4394 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 89.8032 | 86.2254 | oncorhynchus_kisutch | ENSOKIP00005078820 | 91.1898 | 87.5568 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 94.6333 | 92.3971 | oncorhynchus_kisutch | ENSOKIP00005034021 | 94.718 | 92.4799 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 93.7388 | 91.2343 | oncorhynchus_kisutch | ENSOKIP00005117028 | 95.1862 | 92.6431 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 95.0805 | 92.9338 | oncorhynchus_kisutch | ENSOKIP00005074715 | 94.826 | 92.6851 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 95.1699 | 93.0233 | oncorhynchus_mykiss | ENSOMYP00000001570 | 96.1156 | 93.9476 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 94.0072 | 91.3238 | oncorhynchus_mykiss | ENSOMYP00000004009 | 93.7556 | 91.0794 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 94.6333 | 92.3077 | oncorhynchus_mykiss | ENSOMYP00000068529 | 95.5736 | 93.2249 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 92.1288 | 89.4454 | oncorhynchus_mykiss | ENSOMYP00000117807 | 92.8765 | 90.1713 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 94.9911 | 92.7549 | salmo_salar | ENSSSAP00000144476 | 95.935 | 93.6766 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 94.5438 | 92.4866 | salmo_salar | ENSSSAP00000095755 | 95.5696 | 93.4901 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 93.8283 | 91.3238 | salmo_salar | ENSSSAP00000109489 | 95.277 | 92.7339 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 94.0072 | 91.0555 | salmo_salar | ENSSSAP00000098228 | 94.5144 | 91.5468 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 93.7388 | 91.2343 | salmo_trutta | ENSSTUP00000105246 | 95.1862 | 92.6431 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 94.6333 | 92.576 | salmo_trutta | ENSSTUP00000015572 | 94.5487 | 92.4933 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 94.9911 | 92.8444 | salmo_trutta | ENSSTUP00000016247 | 95.0761 | 92.9275 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 93.8283 | 90.966 | salmo_trutta | ENSSTUP00000101695 | 94.3345 | 91.4568 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 93.8283 | 91.2343 | gadus_morhua | ENSGMOP00000008081 | 95.6244 | 92.9809 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 84.1682 | 81.3059 | fundulus_heteroclitus | ENSFHEP00000030731 | 94.9546 | 91.7255 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 92.9338 | 89.2665 | fundulus_heteroclitus | ENSFHEP00000005383 | 93.6036 | 89.9099 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 93.5599 | 90.6977 | poecilia_reticulata | ENSPREP00000014749 | 94.3192 | 91.4337 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 94.186 | 92.2182 | poecilia_reticulata | ENSPREP00000016656 | 95.9891 | 93.9836 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 94.0966 | 92.2182 | xiphophorus_maculatus | ENSXMAP00000002552 | 95.8106 | 93.898 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 90.6977 | 87.5671 | xiphophorus_maculatus | ENSXMAP00000001707 | 93.5424 | 90.3137 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 94.6333 | 92.576 | oryzias_latipes | ENSORLP00000010622 | 96.0945 | 94.0054 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 94.7227 | 92.4866 | cyclopterus_lumpus | ENSCLMP00005001105 | 94.385 | 92.1569 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 93.1127 | 90.7871 | cyclopterus_lumpus | ENSCLMP00005018723 | 93.6151 | 91.277 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 94.2755 | 92.3077 | oreochromis_niloticus | ENSONIP00000058998 | 94.2755 | 92.3077 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 94.0966 | 92.2182 | oreochromis_niloticus | ENSONIP00000013137 | 94.8602 | 92.9666 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 74.6869 | 72.898 | haplochromis_burtoni | ENSHBUP00000012883 | 92.4695 | 90.2547 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 84.2576 | 82.1109 | haplochromis_burtoni | ENSHBUP00000007395 | 93.8247 | 91.4343 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 94.4544 | 92.4866 | astatotilapia_calliptera | ENSACLP00000033452 | 95.9128 | 93.9146 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 93.381 | 91.4132 | astatotilapia_calliptera | ENSACLP00000010541 | 95.2555 | 93.2482 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 94.186 | 92.0394 | sparus_aurata | ENSSAUP00010014918 | 94.6092 | 92.4528 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 94.6333 | 92.6655 | sparus_aurata | ENSSAUP00010022158 | 95.66 | 93.6709 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 94.4544 | 92.3077 | lates_calcarifer | ENSLCAP00010046411 | 94.7085 | 92.5561 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 96.0644 | 95.3488 | xenopus_tropicalis | ENSXETP00000063699 | 97.1946 | 96.4706 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 98.0322 | 97.2272 | chrysemys_picta_bellii | ENSCPBP00000017033 | 98.4726 | 97.664 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 97.8533 | 97.0483 | sphenodon_punctatus | ENSSPUP00000013678 | 98.6474 | 97.8359 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 98.39 | 97.6744 | crocodylus_porosus | ENSCPRP00005022544 | 98.4781 | 97.7619 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 82.3792 | 81.6637 | laticauda_laticaudata | ENSLLTP00000017680 | 97.7707 | 96.9214 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 97.6744 | 97.2272 | notechis_scutatus | ENSNSUP00000007525 | 96.0422 | 95.6025 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 98.2111 | 97.7639 | pseudonaja_textilis | ENSPTXP00000003133 | 97.0822 | 96.6401 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 98.2111 | 97.4955 | anas_platyrhynchos_platyrhynchos | ENSAPLP00000008896 | 98.299 | 97.5828 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 98.39 | 97.585 | gallus_gallus | ENSGALP00010042014 | 98.2143 | 97.4107 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 93.2916 | 92.1288 | meleagris_gallopavo | ENSMGAP00000021802 | 95.0775 | 93.8924 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 93.7388 | 92.9338 | serinus_canaria | ENSSCAP00000016083 | 98.3114 | 97.4672 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 74.6869 | 71.6458 | parus_major | ENSPMJP00000017881 | 89.9784 | 86.3147 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 91.771 | 89.7138 | neolamprologus_brichardi | ENSNBRP00000000837 | 94.3882 | 92.2723 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 94.4544 | 92.4866 | neolamprologus_brichardi | ENSNBRP00000029009 | 92.4694 | 90.5429 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 98.1216 | 97.585 | naja_naja | ENSNNAP00000002815 | 96.9938 | 96.4633 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 98.2111 | 97.6744 | podarcis_muralis | ENSPMRP00000033661 | 97.0822 | 96.5517 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 92.3971 | 91.771 | geospiza_fortis | ENSGFOP00000006283 | 98.2873 | 97.6213 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 98.3005 | 97.585 | taeniopygia_guttata | ENSTGUP00000001084 | 98.3885 | 97.6723 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 95.975 | 95.1699 | erpetoichthys_calabaricus | ENSECRP00000018059 | 97.5455 | 96.7273 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 94.8122 | 92.8444 | kryptolebias_marmoratus | ENSKMAP00000006602 | 96.2761 | 94.2779 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 97.4061 | 96.9589 | salvator_merianae | ENSSMRP00000029871 | 82.5625 | 82.1835 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 94.4544 | 92.6655 | oryzias_javanicus | ENSOJAP00000022740 | 95.9128 | 94.0963 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 88.7299 | 87.1199 | amphilophus_citrinellus | ENSACIP00000014157 | 96.875 | 95.1172 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 93.5599 | 91.6816 | amphilophus_citrinellus | ENSACIP00000025783 | 95.438 | 93.5219 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 94.7227 | 92.6655 | dicentrarchus_labrax | ENSDLAP00005046420 | 94.5536 | 92.5 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 93.8283 | 91.771 | dicentrarchus_labrax | ENSDLAP00005012646 | 93.4105 | 91.3624 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 94.8122 | 92.8444 | amphiprion_percula | ENSAPEP00000008783 | 96.2761 | 94.2779 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 94.5438 | 92.4866 | amphiprion_percula | ENSAPEP00000023048 | 94.9686 | 92.9021 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 94.6333 | 92.4866 | oryzias_sinensis | ENSOSIP00000042146 | 94.2959 | 92.1569 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 67.263 | 66.9946 | pelodiscus_sinensis | ENSPSIP00000010461 | 99.2084 | 98.8127 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 97.8533 | 97.1377 | gopherus_evgoodei | ENSGEVP00005027471 | 98.7365 | 98.0144 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 95.5277 | 94.3649 | chelonoidis_abingdonii | ENSCABP00000022072 | 97.5342 | 96.347 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 94.5438 | 92.3971 | seriola_dumerili | ENSSDUP00000018286 | 94.7982 | 92.6457 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 94.9016 | 92.9338 | seriola_dumerili | ENSSDUP00000013281 | 96.2795 | 94.2831 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 93.9177 | 91.5921 | cottoperca_gobio | ENSCGOP00000033482 | 94.4245 | 92.0863 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 94.5438 | 92.576 | cottoperca_gobio | ENSCGOP00000030248 | 94.6285 | 92.6589 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 93.6494 | 93.0233 | struthio_camelus_australis | ENSSCUP00000013837 | 95.8791 | 95.2381 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 93.2916 | 92.6655 | anser_brachyrhynchus | ENSABRP00000005609 | 98.4891 | 97.8281 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 93.2021 | 90.966 | gasterosteus_aculeatus | ENSGACP00000020456 | 93.4529 | 91.2108 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 94.3649 | 92.3971 | gasterosteus_aculeatus | ENSGACP00000010750 | 94.7038 | 92.7289 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 89.7138 | 86.8515 | cynoglossus_semilaevis | ENSCSEP00000027006 | 93.3023 | 90.3256 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 94.3649 | 92.4866 | cynoglossus_semilaevis | ENSCSEP00000025320 | 96.0838 | 94.1712 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 94.2755 | 92.3971 | poecilia_formosa | ENSPFOP00000000758 | 96.0802 | 94.1659 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 93.2021 | 90.161 | poecilia_formosa | ENSPFOP00000004560 | 94.1283 | 91.0569 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 95.0805 | 93.4705 | myripristis_murdjan | ENSMMDP00005027456 | 96.461 | 94.8276 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 94.3649 | 92.4866 | myripristis_murdjan | ENSMMDP00005035276 | 94.534 | 92.6523 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 94.4544 | 92.3077 | sander_lucioperca | ENSSLUP00000031277 | 94.5389 | 92.3903 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 94.2755 | 91.9499 | sander_lucioperca | ENSSLUP00000008937 | 94.614 | 92.2801 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 98.3005 | 97.585 | strigops_habroptila | ENSSHBP00005020370 | 97.7758 | 97.0641 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 94.5438 | 92.4866 | amphiprion_ocellaris | ENSAOCP00000013856 | 94.9686 | 92.9021 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 94.8122 | 92.8444 | amphiprion_ocellaris | ENSAOCP00000021516 | 96.2761 | 94.2779 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 98.39 | 97.6744 | terrapene_carolina_triunguis | ENSTMTP00000017273 | 98.6547 | 97.9372 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 94.8122 | 92.8444 | hucho_hucho | ENSHHUP00000047946 | 94.9821 | 93.0107 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 94.186 | 91.5027 | hucho_hucho | ENSHHUP00000064237 | 94.6942 | 91.9964 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 94.7227 | 92.4866 | hucho_hucho | ENSHHUP00000024349 | 95.664 | 93.4056 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 92.1288 | 89.6243 | hucho_hucho | ENSHHUP00000022906 | 94.1499 | 91.5905 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 94.186 | 91.8605 | betta_splendens | ENSBSLP00000000983 | 93.934 | 91.6146 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 93.9177 | 91.771 | betta_splendens | ENSBSLP00000056310 | 94.5095 | 92.3492 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 95.7066 | 93.7388 | pygocentrus_nattereri | ENSPNAP00000019041 | 97.2727 | 95.2727 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 94.9016 | 92.8444 | anabas_testudineus | ENSATEP00000062204 | 95.0717 | 93.0107 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 94.3649 | 92.2182 | anabas_testudineus | ENSATEP00000025816 | 94.6188 | 92.4664 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 82.9159 | 73.0769 | ciona_savignyi | ENSCSAVP00000011178 | 84.8124 | 74.7484 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 60.3757 | 45.2594 | saccharomyces_cerevisiae | YMR080C | 69.516 | 52.1112 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 94.9016 | 92.9338 | seriola_lalandi_dorsalis | ENSSLDP00000008708 | 96.2795 | 94.2831 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 94.0072 | 91.8605 | seriola_lalandi_dorsalis | ENSSLDP00000026875 | 95.1131 | 92.9412 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 94.0966 | 91.6816 | labrus_bergylta | ENSLBEP00000019395 | 94.5193 | 92.0934 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 94.7227 | 92.576 | labrus_bergylta | ENSLBEP00000037352 | 96.098 | 93.9201 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 94.4544 | 92.4866 | pundamilia_nyererei | ENSPNYP00000022183 | 95.9128 | 93.9146 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 94.0072 | 91.9499 | pundamilia_nyererei | ENSPNYP00000004833 | 94.7701 | 92.6961 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 94.4544 | 92.1288 | mastacembelus_armatus | ENSMAMP00000009272 | 94.7085 | 92.3767 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 94.2755 | 92.3077 | mastacembelus_armatus | ENSMAMP00000053827 | 93.7722 | 91.8149 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 91.5027 | 89.356 | stegastes_partitus | ENSSPAP00000000003 | 95.0743 | 92.8439 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 94.7227 | 92.8444 | stegastes_partitus | ENSSPAP00000015326 | 96.2727 | 94.3636 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 94.0966 | 91.4132 | oncorhynchus_tshawytscha | ENSOTSP00005068575 | 94.4345 | 91.7415 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 93.7388 | 91.2343 | oncorhynchus_tshawytscha | ENSOTSP00005056657 | 95.1862 | 92.6431 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 95.1699 | 93.0233 | oncorhynchus_tshawytscha | ENSOTSP00005066673 | 96.1156 | 93.9476 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 94.7227 | 92.4866 | oncorhynchus_tshawytscha | ENSOTSP00005053122 | 94.8075 | 92.5694 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 94.7227 | 92.7549 | acanthochromis_polyacanthus | ENSAPOP00000008674 | 96.1853 | 94.1871 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 94.5438 | 92.4866 | acanthochromis_polyacanthus | ENSAPOP00000020196 | 94.9686 | 92.9021 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 98.39 | 97.6744 | aquila_chrysaetos_chrysaetos | ENSACCP00020008733 | 98.4781 | 97.7619 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 94.6333 | 92.6655 | nothobranchius_furzeri | ENSNFUP00015045546 | 94.2119 | 92.2529 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 94.3649 | 92.4866 | cyprinodon_variegatus | ENSCVAP00000025589 | 95.735 | 93.8294 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 95.2594 | 93.9177 | denticeps_clupeoides | ENSDCDP00000025137 | 96.9063 | 95.5414 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 94.7227 | 92.9338 | larimichthys_crocea | ENSLCRP00005054794 | 95.0628 | 93.2675 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 94.186 | 92.1288 | larimichthys_crocea | ENSLCRP00005064618 | 95.0361 | 92.9603 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 94.0072 | 91.3238 | takifugu_rubripes | ENSTRUP00000012294 | 94.0072 | 91.3238 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 94.0072 | 91.3238 | takifugu_rubripes | ENSTRUP00000000308 | 94.5995 | 91.8992 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 93.381 | 92.6655 | ficedula_albicollis | ENSFALP00000025212 | 96.846 | 96.1039 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 94.5438 | 92.2182 | hippocampus_comes | ENSHCOP00000021761 | 96.0909 | 93.7273 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 95.6172 | 93.4705 | cyprinus_carpio_carpio | ENSCCRP00000065172 | 97.1818 | 95 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 95.5277 | 93.381 | cyprinus_carpio_carpio | ENSCCRP00000013506 | 97.0909 | 94.9091 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 98.3005 | 97.585 | coturnix_japonica | ENSCJPP00005013449 | 98.3885 | 97.6723 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 94.2755 | 92.3971 | poecilia_latipinna | ENSPLAP00000027526 | 96.0802 | 94.1659 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 93.2916 | 90.2505 | poecilia_latipinna | ENSPLAP00000014427 | 94.2186 | 91.1472 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 79.6959 | 76.8336 | sinocyclocheilus_grahami | ENSSGRP00000007313 | 94.186 | 90.8034 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 95.1699 | 93.0233 | sinocyclocheilus_grahami | ENSSGRP00000083200 | 95.3405 | 93.19 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 94.0072 | 91.9499 | maylandia_zebra | ENSMZEP00005004537 | 94.7701 | 92.6961 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 94.4544 | 92.4866 | maylandia_zebra | ENSMZEP00005021871 | 95.9128 | 93.9146 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 93.7388 | 91.1449 | tetraodon_nigroviridis | ENSTNIP00000014011 | 93.0728 | 90.4973 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 92.7549 | 89.9821 | tetraodon_nigroviridis | ENSTNIP00000002898 | 93.1716 | 90.3863 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 88.8193 | 87.3882 | paramormyrops_kingsleyae | ENSPKIP00000021830 | 95.5727 | 94.0327 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 95.975 | 95.0805 | scleropages_formosus | ENSSFOP00015072781 | 94.2054 | 93.3275 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 96.2433 | 95.5277 | leptobrachium_leishanense | ENSLLEP00000027898 | 97.8182 | 97.0909 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 91.1449 | 88.8193 | scophthalmus_maximus | ENSSMAP00000070453 | 92.9744 | 90.6022 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 94.4544 | 92.4866 | scophthalmus_maximus | ENSSMAP00000056523 | 93.8667 | 91.9111 |
| ENSG00000005007 | homo_sapiens | ENSP00000262803 | 94.5438 | 92.6655 | oryzias_melastigma | ENSOMEP00000023512 | 96.0036 | 94.0963 |
Gene Ontology
| Go ID | Go term | No. evidence | Entries | Species | Category |
|---|---|---|---|---|---|
| GO:0000184 | involved_in nuclear-transcribed mRNA catabolic process, nonsense-mediated decay | 5 | IBA,IDA,IMP,NAS,TAS | Homo_sapiens(9606) | Process |
| GO:0000781 | located_in chromosome, telomeric region | 1 | IDA | Homo_sapiens(9606) | Component |
| GO:0000785 | part_of chromatin | 1 | IDA | Homo_sapiens(9606) | Component |
| GO:0000932 | located_in P-body | 1 | IEA | Homo_sapiens(9606) | Component |
| GO:0000956 | involved_in nuclear-transcribed mRNA catabolic process | 1 | IMP | Homo_sapiens(9606) | Process |
| GO:0003682 | enables chromatin binding | 1 | IDA | Homo_sapiens(9606) | Function |
| GO:0003723 | enables RNA binding | 4 | HDA,IBA,IDA,NAS | Homo_sapiens(9606) | Function |
| GO:0003724 | enables RNA helicase activity | 2 | IBA,IDA | Homo_sapiens(9606) | Function |
| GO:0004386 | enables helicase activity | 1 | NAS | Homo_sapiens(9606) | Function |
| GO:0005515 | enables protein binding | 1 | IPI | Homo_sapiens(9606) | Function |
| GO:0005524 | enables ATP binding | 1 | IEA | Homo_sapiens(9606) | Function |
| GO:0005634 | located_in nucleus | 1 | IDA | Homo_sapiens(9606) | Component |
| GO:0005654 | located_in nucleoplasm | 1 | IDA | Homo_sapiens(9606) | Component |
| GO:0005737 | is_active_in cytoplasm | 2 | IBA,NAS | Homo_sapiens(9606) | Component |
| GO:0005829 | located_in cytosol | 2 | IDA,TAS | Homo_sapiens(9606) | Component |
| GO:0006260 | involved_in DNA replication | 1 | IMP | Homo_sapiens(9606) | Process |
| GO:0006281 | involved_in DNA repair | 1 | IDA | Homo_sapiens(9606) | Process |
| GO:0006406 | involved_in mRNA export from nucleus | 1 | TAS | Homo_sapiens(9606) | Process |
| GO:0006449 | involved_in regulation of translational termination | 2 | IMP,NAS | Homo_sapiens(9606) | Process |
| GO:0008270 | enables zinc ion binding | 1 | IEA | Homo_sapiens(9606) | Function |
| GO:0016887 | enables ATP hydrolysis activity | 1 | IDA | Homo_sapiens(9606) | Function |
| GO:0032201 | involved_in telomere maintenance via semi-conservative replication | 1 | IDA | Homo_sapiens(9606) | Process |
| GO:0032204 | involved_in regulation of telomere maintenance | 1 | IMP | Homo_sapiens(9606) | Process |
| GO:0032508 | involved_in DNA duplex unwinding | 1 | IDA | Homo_sapiens(9606) | Process |
| GO:0035145 | part_of exon-exon junction complex | 1 | IDA | Homo_sapiens(9606) | Component |
| GO:0036121 | enables double-stranded DNA helicase activity | 1 | IDA | Homo_sapiens(9606) | Function |
| GO:0042162 | enables telomeric DNA binding | 1 | IDA | Homo_sapiens(9606) | Function |
| GO:0044530 | part_of supraspliceosomal complex | 1 | IDA | Homo_sapiens(9606) | Component |
| GO:0044770 | involved_in cell cycle phase transition | 1 | IMP | Homo_sapiens(9606) | Process |
| GO:0044877 | enables protein-containing complex binding | 1 | IPI | Homo_sapiens(9606) | Function |
| GO:0048471 | located_in perinuclear region of cytoplasm | 1 | IEA | Homo_sapiens(9606) | Component |
| GO:0061014 | involved_in positive regulation of mRNA catabolic process | 2 | IDA,IMP | Homo_sapiens(9606) | Process |
| GO:0061158 | involved_in 3-UTR-mediated mRNA destabilization | 2 | IDA,TAS | Homo_sapiens(9606) | Process |
| GO:0071044 | involved_in histone mRNA catabolic process | 1 | IMP | Homo_sapiens(9606) | Process |
| GO:0071222 | involved_in cellular response to lipopolysaccharide | 1 | TAS | Homo_sapiens(9606) | Process |
| GO:0071347 | involved_in cellular response to interleukin-1 | 1 | TAS | Homo_sapiens(9606) | Process |