Functions and Diseases

RBP Type Non-canonical_RBPs
Diseases CancerSARS-COV-2
Drug N.A.
Main interacting RNAs N.A.
Moonlighting functions N.A.
Localizations N.A.
BulkPerturb-seq DataSet_01_207 DataSet_01_341

Description

Ensembl ID ENSG00000004478 Gene ID 2288 Accession 3720
Symbol FKBP4 Alias HBI;p52;Hsp56;FKBP51;FKBP52;FKBP59;PPIase Full Name FKBP prolyl isomerase 4
Status Confidence Length 10454 bases Strand Plus strand
Position 12 : 2794970 - 2805423 RNA binding domain N.A.
Summary The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It has high structural and functional similarity to FK506-binding protein 1A (FKBP1A), but unlike FKBP1A, this protein does not have immunosuppressant activity when complexed with FK506. It interacts with interferon regulatory factor-4 and plays an important role in immunoregulatory gene expression in B and T lymphocytes. This encoded protein is known to associate with phytanoyl-CoA alpha-hydroxylase. It can also associate with two heat shock proteins (hsp90 and hsp70) and thus may play a role in the intracellular trafficking of hetero-oligomeric forms of the steroid hormone receptors. This protein correlates strongly with adeno-associated virus type 2 vectors (AAV) resulting in a significant increase in AAV-mediated transgene expression in human cell lines. Thus this encoded protein is thought to have important implications for the optimal use of AAV vectors in human gene therapy. The human genome contains several non-transcribed pseudogenes similar to this gene. [provided by RefSeq, Sep 2008]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal

Transcripts

Name Transcript ID bp Protein Translation ID
FKBP4-201 ENST00000001008 3715 459aa ENSP00000001008
FKBP4-206 ENST00000543769 425 51aa ENSP00000439703
FKBP4-208 ENST00000630279 156 51aa ENSP00000486800
FKBP4-204 ENST00000540260 777 No protein -
FKBP4-202 ENST00000538622 572 86aa ENSP00000446368
FKBP4-205 ENST00000543037 727 No protein -
FKBP4-203 ENST00000539181 370 84aa ENSP00000438491
FKBP4-207 ENST00000544366 287 23aa ENSP00000442193

Gene Model

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000004478homo_sapiensENSP0000031723225.085915.8076homo_sapiensENSP0000000100831.808320.0436
ENSG00000004478homo_sapiensENSP0000047676728.571418.4019homo_sapiensENSP0000000100825.708116.5577
ENSG00000004478homo_sapiensENSP0000041315242.792825.2252homo_sapiensENSP0000000100820.697212.2004
ENSG00000004478homo_sapiensENSP0000031093545.774631.6901homo_sapiensENSP0000000100814.16129.80392
ENSG00000004478homo_sapiensENSP0000025203738.837923.5474homo_sapiensENSP0000000100827.668816.7756
ENSG00000004478homo_sapiensENSP0000022280341.706225.1185homo_sapiensENSP0000000100819.172111.5468
ENSG00000004478homo_sapiensENSP0000035969356.481543.5185homo_sapiensENSP0000000100813.289810.2397
ENSG00000004478homo_sapiensENSP0000037037358.333341.6667homo_sapiensENSP0000000100813.72559.80392
ENSG00000004478homo_sapiensENSP0000038300358.333345.3704homo_sapiensENSP0000000100813.725510.6754
ENSG00000004478homo_sapiensENSP0000023825612.55137.3831homo_sapiensENSP0000000100833.333319.6078
ENSG00000004478homo_sapiensENSP0000044975138.80622.3881homo_sapiensENSP0000000100816.99359.80392
ENSG00000004478homo_sapiensENSP0000036429827.507215.7593homo_sapiensENSP0000000100820.91511.9826
ENSG00000004478homo_sapiensENSP0000025636731.98220.2703homo_sapiensENSP0000000100815.46849.80392
ENSG00000004478homo_sapiensENSP0000034981173.304254.267homo_sapiensENSP0000000100872.984754.0305
ENSG00000004478homo_sapiensENSP0000037937438.392925homo_sapiensENSP0000000100818.736412.2004
ENSG00000004478homo_sapiensENSP0000024220925.263214.7368homo_sapiensENSP0000000100831.372518.3007
ENSG00000004478homo_sapiensENSP0000032526637.426922.2222homo_sapiensENSP0000000100813.94348.27887
ENSG00000004478homo_sapiensENSP0000031176029.288719.6653homo_sapiensENSP0000000100815.250510.2397

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000004478homo_sapiensENSP0000000100892.374791.939nomascus_leucogenysENSNLEP0000000348010099.5283
ENSG00000004478homo_sapiensENSP0000000100899.128598.6928pan_paniscusENSPPAP0000000181699.780799.3421
ENSG00000004478homo_sapiensENSP0000000100899.346498.6928pongo_abeliiENSPPYP0000000473299.346498.6928
ENSG00000004478homo_sapiensENSP0000000100810099.7821pan_troglodytesENSPTRP0000000775110099.7821
ENSG00000004478homo_sapiensENSP0000000100894.989194.1176gorilla_gorillaENSGGOP0000001021696.247295.3642
ENSG00000004478homo_sapiensENSP0000000100877.124265.1416ornithorhynchus_anatinusENSOANP0000000165785.714372.3971
ENSG00000004478homo_sapiensENSP0000000100892.592683.878sarcophilus_harrisiiENSSHAP0000001643092.391383.6957
ENSG00000004478homo_sapiensENSP0000000100889.324681.0458notamacropus_eugeniiENSMEUP0000000748889.912381.5789
ENSG00000004478homo_sapiensENSP0000000100842.047939.6514choloepus_hoffmanniENSCHOP0000000758263.486859.8684
ENSG00000004478homo_sapiensENSP0000000100893.681987.3638dasypus_novemcinctusENSDNOP0000000871993.886587.5546
ENSG00000004478homo_sapiensENSP0000000100888.235380.61erinaceus_europaeusENSEEUP0000000000896.428688.0952
ENSG00000004478homo_sapiensENSP0000000100855.991352.0697echinops_telfairiENSETEP0000001572061.483357.177
ENSG00000004478homo_sapiensENSP0000000100887.581782.7887callithrix_jacchusENSCJAP0000007990577.159372.9367
ENSG00000004478homo_sapiensENSP0000000100810098.9107cercocebus_atysENSCATP0000002274410098.9107
ENSG00000004478homo_sapiensENSP0000000100890.196189.3246macaca_fascicularisENSMFAP0000004555410099.0338
ENSG00000004478homo_sapiensENSP0000000100899.564398.4749macaca_mulattaENSMMUP0000000971899.564398.4749
ENSG00000004478homo_sapiensENSP0000000100899.564398.4749macaca_nemestrinaENSMNEP0000000161399.564398.4749
ENSG00000004478homo_sapiensENSP0000000100894.771292.8105papio_anubisENSPANP0000003606687.525285.7143
ENSG00000004478homo_sapiensENSP0000000100892.374791.5033mandrillus_leucophaeusENSMLEP0000001400610099.0566
ENSG00000004478homo_sapiensENSP0000000100896.296388.671tursiops_truncatusENSTTRP0000000502596.506688.8646
ENSG00000004478homo_sapiensENSP0000000100898.039292.8105vulpes_vulpesENSVVUP0000002497998.039292.8105
ENSG00000004478homo_sapiensENSP0000000100895.424889.5425mus_spretusMGP_SPRETEiJ_P007952695.633289.738
ENSG00000004478homo_sapiensENSP0000000100897.167891.7211equus_asinusENSEASP0000502518197.167891.7211
ENSG00000004478homo_sapiensENSP0000000100894.335588.2353capra_hircusENSCHIP0000000613294.335588.2353
ENSG00000004478homo_sapiensENSP0000000100881.699374.2919loxodonta_africanaENSLAFP0000001906689.285781.1905
ENSG00000004478homo_sapiensENSP0000000100897.167891.5033panthera_leoENSPLOP0000001670397.167891.5033
ENSG00000004478homo_sapiensENSP0000000100894.117688.671ailuropoda_melanoleucaENSAMEP0000003297491.525486.2288
ENSG00000004478homo_sapiensENSP0000000100894.989188.4532bos_indicus_hybridENSBIXP0000501937094.989188.4532
ENSG00000004478homo_sapiensENSP0000000100896.514289.9782oryctolagus_cuniculusENSOCUP0000004819489.676183.6032
ENSG00000004478homo_sapiensENSP0000000100896.296389.9782equus_caballusENSECAP0000003790695.464489.2009
ENSG00000004478homo_sapiensENSP0000000100897.603591.7211canis_lupus_familiarisENSCAFP0084503501597.603591.7211
ENSG00000004478homo_sapiensENSP0000000100897.167891.5033panthera_pardusENSPPRP0000000120097.167891.5033
ENSG00000004478homo_sapiensENSP0000000100896.514291.5033marmota_marmota_marmotaENSMMMP0000002146597.577192.511
ENSG00000004478homo_sapiensENSP0000000100896.078489.1068balaenoptera_musculusENSBMSP0001003111195.454588.5281
ENSG00000004478homo_sapiensENSP0000000100895.642788.671cavia_porcellusENSCPOP0000000223495.851588.8646
ENSG00000004478homo_sapiensENSP0000000100896.296390.8497felis_catusENSFCAP0000003036495.258689.8707
ENSG00000004478homo_sapiensENSP0000000100897.603591.7211ursus_americanusENSUAMP0000002704697.603591.7211
ENSG00000004478homo_sapiensENSP0000000100891.503382.3529monodelphis_domesticaENSMODP0000002288690.909181.8182
ENSG00000004478homo_sapiensENSP0000000100890.196182.5708bison_bison_bisonENSBBBP0000001889492.410784.5982
ENSG00000004478homo_sapiensENSP0000000100895.860688.4532monodon_monocerosENSMMNP0001501893179.854873.6842
ENSG00000004478homo_sapiensENSP0000000100834.204829.6296monodon_monocerosENSMMNP0001502169187.222275.5556
ENSG00000004478homo_sapiensENSP0000000100895.424889.7603sus_scrofaENSSSCP0000006599896.263790.5495
ENSG00000004478homo_sapiensENSP0000000100897.385692.3747microcebus_murinusENSMICP0000000008884.022679.6992
ENSG00000004478homo_sapiensENSP0000000100879.08571.2418octodon_degusENSODEP0000001761089.189280.344
ENSG00000004478homo_sapiensENSP0000000100886.274581.4815octodon_degusENSODEP0000000013392.09386.9767
ENSG00000004478homo_sapiensENSP0000000100894.771286.4924jaculus_jaculusENSJJAP0000001540895.18686.8709
ENSG00000004478homo_sapiensENSP0000000100891.067584.0959ovis_aries_rambouilletENSOARP0002001581883.101476.7396
ENSG00000004478homo_sapiensENSP0000000100888.017482.3529ursus_maritimusENSUMAP0000001997897.584591.3043
ENSG00000004478homo_sapiensENSP0000000100894.989188.671ochotona_princepsENSOPRP0000001405995.61489.2544
ENSG00000004478homo_sapiensENSP0000000100832.461928.5403delphinapterus_leucasENSDLEP0000003040486.127275.7225
ENSG00000004478homo_sapiensENSP0000000100895.642788.2353delphinapterus_leucasENSDLEP0000003092482.209775.8427
ENSG00000004478homo_sapiensENSP0000000100895.424888.8889physeter_catodonENSPCTP0000502811494.396687.931
ENSG00000004478homo_sapiensENSP0000000100895.20789.9782mus_caroliMGP_CAROLIEiJ_P007627595.414890.1747
ENSG00000004478homo_sapiensENSP0000000100895.424889.7603mus_musculusENSMUSP0000003250895.633289.9563
ENSG00000004478homo_sapiensENSP0000000100888.888982.1351dipodomys_ordiiENSDORP0000002001691.071484.1518
ENSG00000004478homo_sapiensENSP0000000100896.73291.2854mustela_putorius_furoENSMPUP0000000934388.622883.6327
ENSG00000004478homo_sapiensENSP0000000100898.910797.3856aotus_nancymaaeENSANAP0000002928898.910797.3856
ENSG00000004478homo_sapiensENSP0000000100893.681991.0675saimiri_boliviensis_boliviensisENSSBOP0000002919197.285194.5701
ENSG00000004478homo_sapiensENSP0000000100899.782198.9107chlorocebus_sabaeusENSCSAP0000000750799.782198.9107
ENSG00000004478homo_sapiensENSP0000000100860.566458.3878tupaia_belangeriENSTBEP0000000975271.649569.0722
ENSG00000004478homo_sapiensENSP0000000100873.420566.8845mesocricetus_auratusENSMAUP0000000141187.080179.3282
ENSG00000004478homo_sapiensENSP0000000100896.296391.2854mesocricetus_auratusENSMAUP0000000633896.506691.4847
ENSG00000004478homo_sapiensENSP0000000100895.860688.4532phocoena_sinusENSPSNP0000001406196.069988.6463
ENSG00000004478homo_sapiensENSP0000000100894.771288.671camelus_dromedariusENSCDRP0000503294894.771288.671
ENSG00000004478homo_sapiensENSP0000000100888.235382.7887carlito_syrichtaENSTSYP0000002611089.01183.5165
ENSG00000004478homo_sapiensENSP0000000100888.888982.7887panthera_tigris_altaicaENSPTIP0000001227191.891985.5856
ENSG00000004478homo_sapiensENSP0000000100895.20789.9782rattus_norvegicusENSRNOP0000000873795.414890.1747
ENSG00000004478homo_sapiensENSP0000000100897.385692.8105prolemur_simusENSPSMP0000002035097.385692.8105
ENSG00000004478homo_sapiensENSP0000000100895.20789.5425microtus_ochrogasterENSMOCP0000000473095.623689.9344
ENSG00000004478homo_sapiensENSP0000000100895.424891.0675peromyscus_maniculatus_bairdiiENSPEMP0000002003595.633291.2664
ENSG00000004478homo_sapiensENSP0000000100895.424888.671bos_mutusENSBMUP0000002400395.424888.671
ENSG00000004478homo_sapiensENSP0000000100892.374787.5817mus_spicilegusENSMSIP0000002907195.927690.9502
ENSG00000004478homo_sapiensENSP0000000100895.860691.0675cricetulus_griseus_chok1gshdENSCGRP0000102314896.069991.2664
ENSG00000004478homo_sapiensENSP0000000100888.017482.5708pteropus_vampyrusENSPVAP0000000872987.826182.3913
ENSG00000004478homo_sapiensENSP0000000100892.156985.6209myotis_lucifugusENSMLUP0000000945492.358185.8079
ENSG00000004478homo_sapiensENSP0000000100884.749576.4706vombatus_ursinusENSVURP0001001101191.314682.3944
ENSG00000004478homo_sapiensENSP0000000100894.989189.9782rhinolophus_ferrumequinumENSRFEP0001003043394.989189.9782
ENSG00000004478homo_sapiensENSP0000000100891.721186.2745neovison_visonENSNVIP0000000623995.899890.205
ENSG00000004478homo_sapiensENSP0000000100894.989188.4532bos_taurusENSBTAP0000000999894.989188.4532
ENSG00000004478homo_sapiensENSP0000000100896.514290.6318heterocephalus_glaber_femaleENSHGLP0000000382886.862781.5686
ENSG00000004478homo_sapiensENSP0000000100895.642793.0283rhinopithecus_bietiENSRBIP0000002692184.585782.2736
ENSG00000004478homo_sapiensENSP0000000100897.603591.7211canis_lupus_dingoENSCAFP0002001845297.603591.7211
ENSG00000004478homo_sapiensENSP0000000100896.514291.5033sciurus_vulgarisENSSVLP0000501150196.724991.7031
ENSG00000004478homo_sapiensENSP0000000100896.73291.7211sciurus_vulgarisENSSVLP0000501158896.73291.7211
ENSG00000004478homo_sapiensENSP0000000100891.93983.0065phascolarctos_cinereusENSPCIP0000003130091.540182.6464
ENSG00000004478homo_sapiensENSP0000000100874.291967.1024procavia_capensisENSPCAP0000000972574.454167.2489
ENSG00000004478homo_sapiensENSP0000000100896.078489.5425nannospalax_galiliENSNGAP0000002475396.710590.1316
ENSG00000004478homo_sapiensENSP0000000100816.775614.8148bos_grunniensENSBGRP0000002978379.381470.1031
ENSG00000004478homo_sapiensENSP0000000100895.424888.671bos_grunniensENSBGRP0000002293395.424888.671
ENSG00000004478homo_sapiensENSP0000000100896.078490.4139chinchilla_lanigeraENSCLAP0000001969991.87586.4583
ENSG00000004478homo_sapiensENSP0000000100895.860689.1068cervus_hanglu_yarkandensisENSCHYP0000002133995.860689.1068
ENSG00000004478homo_sapiensENSP0000000100894.771288.4532catagonus_wagneriENSCWAP0000001631595.394789.0351
ENSG00000004478homo_sapiensENSP0000000100897.603593.0283ictidomys_tridecemlineatusENSSTOP0000002375197.603593.0283
ENSG00000004478homo_sapiensENSP0000000100895.642790.4139otolemur_garnettiiENSOGAP0000001371895.851590.6114
ENSG00000004478homo_sapiensENSP0000000100898.257196.0784cebus_imitatorENSCCAP0000002912398.257196.0784
ENSG00000004478homo_sapiensENSP0000000100897.385692.5926urocitellus_parryiiENSUPAP0001001629897.385692.5926
ENSG00000004478homo_sapiensENSP0000000100895.642788.671moschus_moschiferusENSMMSP0000002199095.642788.671
ENSG00000004478homo_sapiensENSP0000000100892.156991.5033rhinopithecus_roxellanaENSRROP0000001906892.156991.5033
ENSG00000004478homo_sapiensENSP0000000100895.860689.3246mus_pahariMGP_PahariEiJ_P005264296.069989.5197
ENSG00000004478homo_sapiensENSP0000000100898.039293.2462propithecus_coquereliENSPCOP0000001676998.039293.2462
ENSG00000004478homo_sapiensENSP0000000100818.08289.36819caenorhabditis_elegansZC455.10.132.046316.6023
ENSG00000004478homo_sapiensENSP0000000100820.261410.4575caenorhabditis_elegansC50F2.6b.13116
ENSG00000004478homo_sapiensENSP0000000100819.3911.7647ciona_intestinalisENSCINP0000002750141.395325.1163
ENSG00000004478homo_sapiensENSP0000000100872.766954.4662eptatretus_burgeriENSEBUP0000000846269.438751.9751
ENSG00000004478homo_sapiensENSP0000000100877.995661.22callorhinchus_miliiENSCMIP0000003048876.332659.9147
ENSG00000004478homo_sapiensENSP0000000100874.509857.2985latimeria_chalumnaeENSLACP0000000848573.233456.3169
ENSG00000004478homo_sapiensENSP0000000100880.174365.1416lepisosteus_oculatusENSLOCP0000002087080.525265.4267
ENSG00000004478homo_sapiensENSP0000000100875.599158.6057clupea_harengusENSCHAP0000004287775.9358.8621
ENSG00000004478homo_sapiensENSP0000000100881.481560.7843danio_rerioENSDARP0000012477283.111162
ENSG00000004478homo_sapiensENSP0000000100880.174362.3094carassius_auratusENSCARP0000008790181.777863.5556
ENSG00000004478homo_sapiensENSP0000000100880.174362.0915carassius_auratusENSCARP0000009519581.777863.3333
ENSG00000004478homo_sapiensENSP0000000100880.6162.7451carassius_auratusENSCARP0000001050382.222264
ENSG00000004478homo_sapiensENSP0000000100879.520761.4379astyanax_mexicanusENSAMXP0000000392981.838663.2287
ENSG00000004478homo_sapiensENSP0000000100879.08561.4379ictalurus_punctatusENSIPUP0000001273881.390163.2287
ENSG00000004478homo_sapiensENSP0000000100878.213560.7843esox_luciusENSELUP0000004355580.855962.8378
ENSG00000004478homo_sapiensENSP0000000100878.213560.7843electrophorus_electricusENSEEEP0000003273580.493362.5561
ENSG00000004478homo_sapiensENSP0000000100874.509858.8235oncorhynchus_kisutchENSOKIP0000507674872.304457.0825
ENSG00000004478homo_sapiensENSP0000000100876.034958.8235oncorhynchus_kisutchENSOKIP0000504507670.647854.6559
ENSG00000004478homo_sapiensENSP0000000100873.638358.3878oncorhynchus_mykissENSOMYP0000002660969.690755.2577
ENSG00000004478homo_sapiensENSP0000000100875.163457.7342oncorhynchus_mykissENSOMYP0000006210775.657958.114
ENSG00000004478homo_sapiensENSP0000000100873.856258.1699salmo_salarENSSSAP0000001537569.183754.4898
ENSG00000004478homo_sapiensENSP0000000100874.509857.2985salmo_salarENSSSAP0000005171775.330457.9295
ENSG00000004478homo_sapiensENSP0000000100873.420556.8627salmo_salarENSSSAP0000016432876.765459.4533
ENSG00000004478homo_sapiensENSP0000000100874.945557.2985salmo_truttaENSSTUP0000007116976.444458.4444
ENSG00000004478homo_sapiensENSP0000000100873.420558.3878salmo_truttaENSSTUP0000008690474.888959.5556
ENSG00000004478homo_sapiensENSP0000000100877.124260.5664gadus_morhuaENSGMOP0000000287575.159259.0234
ENSG00000004478homo_sapiensENSP0000000100879.08560.5664fundulus_heteroclitusENSFHEP0000000304679.955961.2335
ENSG00000004478homo_sapiensENSP0000000100878.649260.5664poecilia_reticulataENSPREP0000000818180.580462.0536
ENSG00000004478homo_sapiensENSP0000000100878.649261.0022xiphophorus_maculatusENSXMAP0000000399080.580462.5
ENSG00000004478homo_sapiensENSP0000000100880.6161.8736oryzias_latipesENSORLP0000001125981.677762.6932
ENSG00000004478homo_sapiensENSP0000000100879.302860.7843cyclopterus_lumpusENSCLMP0000500240678.448360.1293
ENSG00000004478homo_sapiensENSP0000000100879.520763.1808oreochromis_niloticusENSONIP0000001894780.219863.7363
ENSG00000004478homo_sapiensENSP0000000100879.08562.5272haplochromis_burtoniENSHBUP0000001450179.780263.0769
ENSG00000004478homo_sapiensENSP0000000100878.649262.3094astatotilapia_callipteraENSACLP0000003427179.340762.8571
ENSG00000004478homo_sapiensENSP0000000100878.867162.3094astatotilapia_callipteraENSACLP0000004080079.560462.8571
ENSG00000004478homo_sapiensENSP0000000100877.559961.0022sparus_aurataENSSAUP0001002866877.391360.8696
ENSG00000004478homo_sapiensENSP0000000100879.08561.6558lates_calcariferENSLCAP0001002202279.431161.9256
ENSG00000004478homo_sapiensENSP0000000100818.300713.0719xenopus_tropicalisENSXETP0000007258473.684252.6316
ENSG00000004478homo_sapiensENSP0000000100881.263666.0131xenopus_tropicalisENSXETP0000008057282.888967.3333
ENSG00000004478homo_sapiensENSP0000000100887.581775.817chrysemys_picta_belliiENSCPBP0000001328288.741776.8212
ENSG00000004478homo_sapiensENSP0000000100886.928173.2026sphenodon_punctatusENSSPUP0000002268486.928173.2026
ENSG00000004478homo_sapiensENSP0000000100879.520767.756crocodylus_porosusENSCPRP0000501870481.655569.5749
ENSG00000004478homo_sapiensENSP0000000100882.788767.1024laticauda_laticaudataENSLLTP0000001597183.15167.3961
ENSG00000004478homo_sapiensENSP0000000100882.788767.1024pseudonaja_textilisENSPTXP0000002265283.15167.3961
ENSG00000004478homo_sapiensENSP0000000100887.14673.8562anas_platyrhynchos_platyrhynchosENSAPLP0000001199689.086975.5011
ENSG00000004478homo_sapiensENSP0000000100885.185273.4205gallus_gallusENSGALP0001003728784.267272.6293
ENSG00000004478homo_sapiensENSP0000000100884.749573.2026meleagris_gallopavoENSMGAP0000001473588.00976.0181
ENSG00000004478homo_sapiensENSP0000000100886.928173.8562serinus_canariaENSSCAP0000002119288.864175.5011
ENSG00000004478homo_sapiensENSP0000000100886.492473.6383parus_majorENSPMJP0000000421788.418775.2784
ENSG00000004478homo_sapiensENSP0000000100869.063254.6841anolis_carolinensisENSACAP0000001498888.300869.9164
ENSG00000004478homo_sapiensENSP0000000100878.867161.8736neolamprologus_brichardiENSNBRP0000002882074.485658.4362
ENSG00000004478homo_sapiensENSP0000000100883.224467.5381naja_najaENSNNAP0000002714563.036351.1551
ENSG00000004478homo_sapiensENSP0000000100861.873650.5447podarcis_muralisENSPMRP0000002828583.775868.4366
ENSG00000004478homo_sapiensENSP0000000100878.867166.8845geospiza_fortisENSGFOP0000001630888.508675.0611
ENSG00000004478homo_sapiensENSP0000000100886.710273.8562taeniopygia_guttataENSTGUP0000001354188.641475.5011
ENSG00000004478homo_sapiensENSP0000000100876.252761.4379erpetoichthys_calabaricusENSECRP0000001474277.262762.2517
ENSG00000004478homo_sapiensENSP0000000100880.392262.3094kryptolebias_marmoratusENSKMAP0000001937781.45763.1347
ENSG00000004478homo_sapiensENSP0000000100884.531671.2418salvator_merianaeENSSMRP0000003051486.414372.8285
ENSG00000004478homo_sapiensENSP0000000100879.956461.0022oryzias_javanicusENSOJAP0000004720280.659361.5385
ENSG00000004478homo_sapiensENSP0000000100876.688560.1307amphilophus_citrinellusENSACIP0000002941881.293363.7413
ENSG00000004478homo_sapiensENSP0000000100880.392262.963dicentrarchus_labraxENSDLAP0000505780981.098963.5165
ENSG00000004478homo_sapiensENSP0000000100879.302862.0915amphiprion_perculaENSAPEP000000204378062.6374
ENSG00000004478homo_sapiensENSP0000000100874.945559.2593oryzias_sinensisENSOSIP0000002543777.303461.1236
ENSG00000004478homo_sapiensENSP0000000100885.838873.2026pelodiscus_sinensisENSPSIP0000001530187.361474.5011
ENSG00000004478homo_sapiensENSP0000000100885.403172.549gopherus_evgoodeiENSGEVP0000500253273.684262.594
ENSG00000004478homo_sapiensENSP0000000100888.235375.817chelonoidis_abingdoniiENSCABP0000001653889.40476.8212
ENSG00000004478homo_sapiensENSP0000000100880.174361.8736seriola_dumeriliENSSDUP0000001781580.879162.4176
ENSG00000004478homo_sapiensENSP0000000100875.381356.427cottoperca_gobioENSCGOP0000000502575.381356.427
ENSG00000004478homo_sapiensENSP0000000100879.738666.8845struthio_camelus_australisENSSCUP0000001983489.486575.0611
ENSG00000004478homo_sapiensENSP0000000100886.710273.4205anser_brachyrhynchusENSABRP0000001471688.641475.0557
ENSG00000004478homo_sapiensENSP0000000100878.213558.1699gasterosteus_aculeatusENSGACP0000001720579.074958.8106
ENSG00000004478homo_sapiensENSP0000000100869.716855.1198cynoglossus_semilaevisENSCSEP0000000617978.817762.3153
ENSG00000004478homo_sapiensENSP0000000100879.08560.7843poecilia_formosaENSPFOP0000001901381.026862.2768
ENSG00000004478homo_sapiensENSP0000000100877.995661.4379myripristis_murdjanENSMMDP0000503119579.203562.3894
ENSG00000004478homo_sapiensENSP0000000100879.956461.8736sander_luciopercaENSSLUP0000000467380.13162.0087
ENSG00000004478homo_sapiensENSP0000000100884.967372.549strigops_habroptilaENSSHBP0000502279085.903173.348
ENSG00000004478homo_sapiensENSP0000000100879.302862.0915amphiprion_ocellarisENSAOCP000000230128062.6374
ENSG00000004478homo_sapiensENSP0000000100888.017476.4706terrapene_carolina_triunguisENSTMTP0000002196089.183277.4834
ENSG00000004478homo_sapiensENSP0000000100877.559960.5664hucho_huchoENSHHUP0000003731074.47758.159
ENSG00000004478homo_sapiensENSP0000000100874.509858.8235hucho_huchoENSHHUP0000007752969.512254.878
ENSG00000004478homo_sapiensENSP0000000100879.08559.9129betta_splendensENSBSLP0000003317879.257660.0437
ENSG00000004478homo_sapiensENSP0000000100878.867161.6558pygocentrus_nattereriENSPNAP0000002402977.516160.5996
ENSG00000004478homo_sapiensENSP0000000100879.738661.8736anabas_testudineusENSATEP0000006270680.616762.5551
ENSG00000004478homo_sapiensENSP0000000100814.59698.93246ciona_savignyiENSCSAVP0000000500747.857129.2857
ENSG00000004478homo_sapiensENSP0000000100813.071910.4575saccharomyces_cerevisiaeYDR519W44.444435.5556
ENSG00000004478homo_sapiensENSP0000000100822.875819.39seriola_lalandi_dorsalisENSSLDP0000000307484.677471.7742
ENSG00000004478homo_sapiensENSP0000000100880.392262.0915seriola_lalandi_dorsalisENSSLDP0000002385481.098962.6374
ENSG00000004478homo_sapiensENSP0000000100822.875819.39seriola_lalandi_dorsalisENSSLDP0000000250784.677471.7742
ENSG00000004478homo_sapiensENSP0000000100877.559961.0022labrus_bergyltaENSLBEP0000002578377.559961.0022
ENSG00000004478homo_sapiensENSP0000000100875.81760.3486pundamilia_nyerereiENSPNYP0000001094975.652260.2174
ENSG00000004478homo_sapiensENSP0000000100880.6160.7843mastacembelus_armatusENSMAMP0000001574880.78660.917
ENSG00000004478homo_sapiensENSP0000000100880.392261.8736stegastes_partitusENSSPAP0000000497781.098962.4176
ENSG00000004478homo_sapiensENSP0000000100873.202657.9521oncorhynchus_tshawytschaENSOTSP0000507502570.292955.6485
ENSG00000004478homo_sapiensENSP0000000100877.124260.1307oncorhynchus_tshawytschaENSOTSP0000507327580.090562.4434
ENSG00000004478homo_sapiensENSP0000000100879.302862.7451acanthochromis_polyacanthusENSAPOP000000116418063.2967
ENSG00000004478homo_sapiensENSP0000000100887.363874.2919aquila_chrysaetos_chrysaetosENSACCP0002002465789.309675.9465
ENSG00000004478homo_sapiensENSP0000000100877.559963.1808nothobranchius_furzeriENSNFUP0001503504474.789960.9244
ENSG00000004478homo_sapiensENSP0000000100878.213559.0414denticeps_clupeoidesENSDCDP0000001292380.493360.7623
ENSG00000004478homo_sapiensENSP0000000100879.08561.4379larimichthys_croceaENSLCRP0000506463379.431161.7068
ENSG00000004478homo_sapiensENSP0000000100876.034958.6057takifugu_rubripesENSTRUP0000003843676.703359.1209
ENSG00000004478homo_sapiensENSP0000000100886.710273.6383ficedula_albicollisENSFALP0000000506488.641475.2784
ENSG00000004478homo_sapiensENSP0000000100819.607816.3399hippocampus_comesENSHCOP0000001342581.818268.1818
ENSG00000004478homo_sapiensENSP0000000100878.213560.3486hippocampus_comesENSHCOP0000001345779.424861.2832
ENSG00000004478homo_sapiensENSP0000000100879.956461.8736cyprinus_carpio_carpioENSCCRP0000007745581.555663.1111
ENSG00000004478homo_sapiensENSP0000000100879.956462.5272cyprinus_carpio_carpioENSCCRP0000007743981.555663.7778
ENSG00000004478homo_sapiensENSP0000000100885.185273.2026coturnix_japonicaENSCJPP0000502072788.461576.0181
ENSG00000004478homo_sapiensENSP0000000100877.124260.1307poecilia_latipinnaENSPLAP0000002493179.017961.6071
ENSG00000004478homo_sapiensENSP0000000100867.538152.7233sinocyclocheilus_grahamiENSSGRP0000006362775.609859.0244
ENSG00000004478homo_sapiensENSP0000000100879.738661.22sinocyclocheilus_grahamiENSSGRP0000006797578.709760.4301
ENSG00000004478homo_sapiensENSP0000000100878.649262.3094maylandia_zebraENSMZEP0000502694279.340762.8571
ENSG00000004478homo_sapiensENSP0000000100877.777863.3987paramormyrops_kingsleyaeENSPKIP0000001596578.634464.0969
ENSG00000004478homo_sapiensENSP0000000100872.984754.4662paramormyrops_kingsleyaeENSPKIP0000003354774.776855.8036
ENSG00000004478homo_sapiensENSP0000000100874.945558.6057scleropages_formosusENSSFOP0001506847776.106259.5133
ENSG00000004478homo_sapiensENSP0000000100872.113352.7233scleropages_formosusENSSFOP0001501073267.967149.692
ENSG00000004478homo_sapiensENSP0000000100837.254930.9368leptobrachium_leishanenseENSLLEP0000002362769.230857.4899
ENSG00000004478homo_sapiensENSP0000000100879.738663.1808scophthalmus_maximusENSSMAP0000000460176.2560.4167
ENSG00000004478homo_sapiensENSP0000000100880.392261.8736oryzias_melastigmaENSOMEP0000000563881.45762.6932

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0000413involved_in protein peptidyl-prolyl isomerization1IBAHomo_sapiens(9606)Process
GO:0003723enables RNA binding1HDAHomo_sapiens(9606)Function
GO:0003755enables peptidyl-prolyl cis-trans isomerase activity2IBA,IDAHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005524enables ATP binding1IEAHomo_sapiens(9606)Function
GO:0005525enables GTP binding1IEAHomo_sapiens(9606)Function
GO:0005528enables FK506 binding1TASHomo_sapiens(9606)Function
GO:0005654located_in nucleoplasm2IDA,TASHomo_sapiens(9606)Component
GO:0005737is_active_in cytoplasm1IBAHomo_sapiens(9606)Component
GO:0005739located_in mitochondrion1IEAHomo_sapiens(9606)Component
GO:0005829located_in cytosol3IDA,ISS,TASHomo_sapiens(9606)Component
GO:0005874located_in microtubule1IEAHomo_sapiens(9606)Component
GO:0006457involved_in protein folding1TASHomo_sapiens(9606)Process
GO:0006463involved_in steroid hormone receptor complex assembly1IEAHomo_sapiens(9606)Process
GO:0006825involved_in copper ion transport1IEAHomo_sapiens(9606)Process
GO:0007566involved_in embryo implantation1IEAHomo_sapiens(9606)Process
GO:0010977involved_in negative regulation of neuron projection development1ISSHomo_sapiens(9606)Process
GO:0030521involved_in androgen receptor signaling pathway1IEAHomo_sapiens(9606)Process
GO:0030674enables protein-macromolecule adaptor activity1TASHomo_sapiens(9606)Function
GO:0030850involved_in prostate gland development1IEAHomo_sapiens(9606)Process
GO:0031072enables heat shock protein binding1IPIHomo_sapiens(9606)Function
GO:0031111involved_in negative regulation of microtubule polymerization or depolymerization1ISSHomo_sapiens(9606)Process
GO:0031115involved_in negative regulation of microtubule polymerization1IEAHomo_sapiens(9606)Process
GO:0031503involved_in protein-containing complex localization1IEAHomo_sapiens(9606)Process
GO:0032767enables copper-dependent protein binding1IEAHomo_sapiens(9606)Function
GO:0032991part_of protein-containing complex1IEAHomo_sapiens(9606)Component
GO:0035259enables nuclear glucocorticoid receptor binding1IEAHomo_sapiens(9606)Function
GO:0043025located_in neuronal cell body1IEAHomo_sapiens(9606)Component
GO:0044295located_in axonal growth cone1ISSHomo_sapiens(9606)Component
GO:0046661involved_in male sex differentiation1IEAHomo_sapiens(9606)Process
GO:0048156enables tau protein binding1IEAHomo_sapiens(9606)Function
GO:0048471located_in perinuclear region of cytoplasm1IEAHomo_sapiens(9606)Component
GO:0051219enables phosphoprotein binding1IEAHomo_sapiens(9606)Function
GO:0061077involved_in chaperone-mediated protein folding2IBA,IDAHomo_sapiens(9606)Process
GO:0070062located_in extracellular exosome1HDAHomo_sapiens(9606)Component

Expression