RBP Type
Non-canonical_RBPs
Diseases
N.A.
Drug
N.A.
Main interacting RNAs
N.A.
Moonlighting functions
Transmemebrane
Localizations
N.A.
BulkPerturb-seq
N.A.
Ensembl ID ENSG00000271425 Gene ID
100132406 Accession
31992
Symbol
NBPF10
Alias
AB6;AG1;NBPF9
Full Name
NBPF member 10
Status
Confidence
Length
164290 bases
Strand
Minus strand
Position
1 : 146064711 - 146229000
RNA binding domain
N.A.
Summary
This gene is a member of the neuroblastoma breakpoint family (NBPF) which consists of dozens of recently duplicated genes primarily located in segmental duplications on human chromosome 1. This gene family has experienced its greatest expansion within the human lineage and has expanded, to a lesser extent, among primates in general. Members of this gene family are characterized by tandemly repeated copies of DUF1220 protein domains. Gene copy number variations in the human chromosomal region 1q21.1, where most DUF1220 domains are located, have been implicated in a number of developmental and neurogenetic diseases such as microcephaly, macrocephaly, autism, schizophrenia, cognitive disability, congenital heart disease, neuroblastoma, and congenital kidney and urinary tract anomalies. Altered expression of some gene family members is associated with several types of cancer. This gene family contains numerous pseudogenes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014]
RNA binding domains (RBDs)
Protein
Domain
Pfam ID
E-value
Domain number
RNA binding proteomes (RBPomes)
Pubmed ID
Full Name
Cell
Author
Time
Doi
Literatures on RNA binding capacity
Pubmed ID
Title
Author
Time
Journal
Name
Transcript ID
bp
Protein
Translation ID
NBPF10-201
ENST00000583866
13030
3795aa
ENSP00000463957
NBPF10-203
ENST00000617010
11630
1239aa
ENSP00000479344
NBPF10-202
ENST00000612520
3411
750aa
ENSP00000483006
Pathway ID
Pathway Name
Source
ensgID
Trait
pValue
Pubmed ID
ensgID SNP Chromosome Position
Trait PubmedID Or or BEAT
EFO ID
Protein-Protein Interaction (PPI)
Ensembl ID
Source
Target
Species
Protein ID
Perc_pos
Perc_id
Species
Protein ID
Perc_pos
Perc_id
ENSG00000271425 homo_sapiens ENSP00000479693 99.498 98.9625 homo_sapiens ENSP00000463957 78.3399 77.9183 ENSG00000271425 homo_sapiens ENSP00000481542 80.1796 79.2818 homo_sapiens ENSP00000463957 30.5929 30.2503 ENSG00000271425 homo_sapiens ENSP00000513968 96.0396 93.7894 homo_sapiens ENSP00000463957 28.1159 27.4572 ENSG00000271425 homo_sapiens ENSP00000463178 98.5075 97.3134 homo_sapiens ENSP00000463957 17.3913 17.1805 ENSG00000271425 homo_sapiens ENSP00000498781 52.7192 52.1207 homo_sapiens ENSP00000463957 53.386 52.78 ENSG00000271425 homo_sapiens ENSP00000507808 62.3121 60.3468 homo_sapiens ENSP00000463957 14.2029 13.7549 ENSG00000271425 homo_sapiens ENSP00000513610 69.8514 68.6837 homo_sapiens ENSP00000463957 17.3386 17.0487 ENSG00000271425 homo_sapiens ENSP00000513971 44.7495 43.9945 homo_sapiens ENSP00000463957 17.1805 16.8906 ENSG00000271425 homo_sapiens ENSP00000478665 96.7262 95.3869 homo_sapiens ENSP00000463957 17.1278 16.8906 ENSG00000271425 homo_sapiens ENSP00000513969 44.3578 44.039 homo_sapiens ENSP00000463957 65.9816 65.5072 ENSG00000271425 homo_sapiens ENSP00000474456 73.5733 72.2564 homo_sapiens ENSP00000463957 22.0817 21.6864 ENSG00000271425 homo_sapiens ENSP00000316782 85.466 78.515 homo_sapiens ENSP00000463957 14.2556 13.0962 ENSG00000271425 homo_sapiens ENSP00000417277 57.21 44.9843 homo_sapiens ENSP00000463957 9.61792 7.56258 ENSG00000271425 homo_sapiens ENSP00000389237 57.21 44.9843 homo_sapiens ENSP00000463957 9.61792 7.56258
Ensembl ID
Source
Target
Species
Protein ID
Perc_pos
Perc_id
Species
Protein ID
Perc_pos
Perc_id
ENSG00000271425 homo_sapiens ENSP00000463957 1.52833 1.39657 pan_paniscus ENSPPAP00000000095 87.8788 80.303 ENSG00000271425 homo_sapiens ENSP00000463957 6.82477 6.27141 pongo_abelii ENSPPYP00000011943 89.0034 81.7869 ENSG00000271425 homo_sapiens ENSP00000463957 5.55995 5.00659 pan_troglodytes ENSPTRP00000058531 87.1901 78.5124 ENSG00000271425 homo_sapiens ENSP00000463957 15.6785 15.2042 gorilla_gorilla ENSGGOP00000015614 96.748 93.8211 ENSG00000271425 homo_sapiens ENSP00000463957 22.1607 21.1331 gorilla_gorilla ENSGGOP00000016506 90.7228 86.5156 ENSG00000271425 homo_sapiens ENSP00000463957 1.66008 1.55468 gorilla_gorilla ENSGGOP00000050546 88.7324 83.0986 ENSG00000271425 homo_sapiens ENSP00000463957 4.76943 2.7668 choloepus_hoffmanni ENSCHOP00000006839 31.9224 18.5185 ENSG00000271425 homo_sapiens ENSP00000463957 4.66403 2.9249 choloepus_hoffmanni ENSCHOP00000006838 28.7805 18.0488 ENSG00000271425 homo_sapiens ENSP00000463957 2.7141 1.73913 dasypus_novemcinctus ENSDNOP00000025731 63.1902 40.4908 ENSG00000271425 homo_sapiens ENSP00000463957 5.11199 3.16206 dasypus_novemcinctus ENSDNOP00000022334 41.189 25.4777 ENSG00000271425 homo_sapiens ENSP00000463957 5.08564 3.00395 dasypus_novemcinctus ENSDNOP00000028692 29.6923 17.5385 ENSG00000271425 homo_sapiens ENSP00000463957 4.76943 2.79315 dasypus_novemcinctus ENSDNOP00000029772 27.3001 15.9879 ENSG00000271425 homo_sapiens ENSP00000463957 5.71805 3.18841 dasypus_novemcinctus ENSDNOP00000026721 33.9062 18.9062 ENSG00000271425 homo_sapiens ENSP00000463957 2.16074 1.34387 dasypus_novemcinctus ENSDNOP00000033852 65.0794 40.4762 ENSG00000271425 homo_sapiens ENSP00000463957 5.00659 3.00395 dasypus_novemcinctus ENSDNOP00000033709 29.2758 17.5655 ENSG00000271425 homo_sapiens ENSP00000463957 9.35441 8.22134 cercocebus_atys ENSCATP00000033076 74.5798 65.5462 ENSG00000271425 homo_sapiens ENSP00000463957 5.77075 5.34914 cercocebus_atys ENSCATP00000039323 82.3308 76.3158 ENSG00000271425 homo_sapiens ENSP00000463957 7.82609 6.69302 macaca_fascicularis ENSMFAP00000061165 86.8421 74.269 ENSG00000271425 homo_sapiens ENSP00000463957 5.98155 5.03294 macaca_fascicularis ENSMFAP00000060632 79.6491 67.0175 ENSG00000271425 homo_sapiens ENSP00000463957 19.1041 17.1278 macaca_fascicularis ENSMFAP00000055387 85.5962 76.7414 ENSG00000271425 homo_sapiens ENSP00000463957 13.1225 12.0685 macaca_fascicularis ENSMFAP00000050252 83.557 76.8456 ENSG00000271425 homo_sapiens ENSP00000463957 8.37945 7.08827 macaca_mulatta ENSMMUP00000030100 81.9588 69.3299 ENSG00000271425 homo_sapiens ENSP00000463957 18.7615 16.6798 macaca_mulatta ENSMMUP00000075049 82.9837 73.7762 ENSG00000271425 homo_sapiens ENSP00000463957 5.82345 5.45455 macaca_nemestrina ENSMNEP00000029078 87.0079 81.4961 ENSG00000271425 homo_sapiens ENSP00000463957 9.67062 8.722 macaca_nemestrina ENSMNEP00000023422 69.2453 62.4528 ENSG00000271425 homo_sapiens ENSP00000463957 5.7971 5.34914 mandrillus_leucophaeus ENSMLEP00000000536 82.7068 76.3158 ENSG00000271425 homo_sapiens ENSP00000463957 6.87747 4.61133 tursiops_truncatus ENSTTRP00000001894 43.5726 29.2154 ENSG00000271425 homo_sapiens ENSP00000463957 1.26482 0.764163 vulpes_vulpes ENSVVUP00000042817 53.3333 32.2222 ENSG00000271425 homo_sapiens ENSP00000463957 1.26482 0.764163 vulpes_vulpes ENSVVUP00000004827 53.3333 32.2222 ENSG00000271425 homo_sapiens ENSP00000463957 1.60738 1.10672 equus_asinus ENSEASP00005038565 64.8936 44.6809 ENSG00000271425 homo_sapiens ENSP00000463957 2.10804 1.31752 equus_asinus ENSEASP00005038277 59.7015 37.3134 ENSG00000271425 homo_sapiens ENSP00000463957 1.18577 0.764163 equus_asinus ENSEASP00005046732 59.2105 38.1579 ENSG00000271425 homo_sapiens ENSP00000463957 1.21212 0.816864 equus_asinus ENSEASP00005039115 50 33.6957 ENSG00000271425 homo_sapiens ENSP00000463957 4.11067 2.58235 equus_asinus ENSEASP00005058583 44.8276 28.1609 ENSG00000271425 homo_sapiens ENSP00000463957 2.6087 1.73913 equus_asinus ENSEASP00005057780 59.6386 39.759 ENSG00000271425 homo_sapiens ENSP00000463957 2.9249 1.73913 equus_asinus ENSEASP00005052845 48.4716 28.821 ENSG00000271425 homo_sapiens ENSP00000463957 2.8195 1.84453 equus_asinus ENSEASP00005039913 55.1546 36.0825 ENSG00000271425 homo_sapiens ENSP00000463957 1.29117 0.843215 equus_asinus ENSEASP00005010841 54.4444 35.5556 ENSG00000271425 homo_sapiens ENSP00000463957 1.26482 0.869565 equus_asinus ENSEASP00005048425 52.7473 36.2637 ENSG00000271425 homo_sapiens ENSP00000463957 1.29117 0.790514 equus_asinus ENSEASP00005054050 61.25 37.5 ENSG00000271425 homo_sapiens ENSP00000463957 4.37418 2.6087 equus_asinus ENSEASP00005058880 42.3469 25.2551 ENSG00000271425 homo_sapiens ENSP00000463957 1.00132 0.685112 equus_asinus ENSEASP00005008925 63.3333 43.3333 ENSG00000271425 homo_sapiens ENSP00000463957 5.42819 3.39921 equus_asinus ENSEASP00005045994 26.9634 16.8848 ENSG00000271425 homo_sapiens ENSP00000463957 5.6917 3.76812 capra_hircus ENSCHIP00000000304 40.9091 27.0833 ENSG00000271425 homo_sapiens ENSP00000463957 6.50856 4.32148 capra_hircus ENSCHIP00000010543 37.0315 24.5877 ENSG00000271425 homo_sapiens ENSP00000463957 7.06192 4.66403 capra_hircus ENSCHIP00000006316 42.2047 27.874 ENSG00000271425 homo_sapiens ENSP00000463957 7.08827 4.76943 capra_hircus ENSCHIP00000027949 42.4961 28.594 ENSG00000271425 homo_sapiens ENSP00000463957 4.45323 2.9249 bos_indicus_hybrid ENSBIXP00005020069 52 34.1538 ENSG00000271425 homo_sapiens ENSP00000463957 1.00132 0.737813 bos_indicus_hybrid ENSBIXP00005040472 58.4615 43.0769 ENSG00000271425 homo_sapiens ENSP00000463957 1.00132 0.737813 bos_indicus_hybrid ENSBIXP00005042049 58.4615 43.0769 ENSG00000271425 homo_sapiens ENSP00000463957 5.45455 3.26746 oryctolagus_cuniculus ENSOCUP00000017811 28.9106 17.3184 ENSG00000271425 homo_sapiens ENSP00000463957 5.7971 3.53096 oryctolagus_cuniculus ENSOCUP00000007301 37.8007 23.0241 ENSG00000271425 homo_sapiens ENSP00000463957 5.9552 3.63636 oryctolagus_cuniculus ENSOCUP00000015998 41.4679 25.3211 ENSG00000271425 homo_sapiens ENSP00000463957 6.48221 3.97892 oryctolagus_cuniculus ENSOCUP00000044452 37.8462 23.2308 ENSG00000271425 homo_sapiens ENSP00000463957 5.7444 3.45191 oryctolagus_cuniculus ENSOCUP00000005532 43.254 25.9921 ENSG00000271425 homo_sapiens ENSP00000463957 5.55995 3.34651 oryctolagus_cuniculus ENSOCUP00000018518 43.8669 26.4033 ENSG00000271425 homo_sapiens ENSP00000463957 5.32279 3.1357 oryctolagus_cuniculus ENSOCUP00000022215 41.3934 24.3852 ENSG00000271425 homo_sapiens ENSP00000463957 5.66535 3.50461 oryctolagus_cuniculus ENSOCUP00000025078 42.9142 26.5469 ENSG00000271425 homo_sapiens ENSP00000463957 5.45455 3.26746 oryctolagus_cuniculus ENSOCUP00000037303 42.1589 25.2546 ENSG00000271425 homo_sapiens ENSP00000463957 5.27009 3.083 oryctolagus_cuniculus ENSOCUP00000039090 42.4628 24.8408 ENSG00000271425 homo_sapiens ENSP00000463957 4.63768 3.10935 oryctolagus_cuniculus ENSOCUP00000030135 33.3966 22.3909 ENSG00000271425 homo_sapiens ENSP00000463957 6.00791 3.47826 oryctolagus_cuniculus ENSOCUP00000031631 36.1905 20.9524 ENSG00000271425 homo_sapiens ENSP00000463957 1.60738 1.05402 equus_caballus ENSECAP00000021719 64.8936 42.5532 ENSG00000271425 homo_sapiens ENSP00000463957 1.21212 0.816864 equus_caballus ENSECAP00000042954 50 33.6957 ENSG00000271425 homo_sapiens ENSP00000463957 2.13439 1.34387 equus_caballus ENSECAP00000030795 49.3902 31.0976 ENSG00000271425 homo_sapiens ENSP00000463957 2.6614 1.79183 equus_caballus ENSECAP00000063606 59.7633 40.2367 ENSG00000271425 homo_sapiens ENSP00000463957 8.22134 5.13834 felis_catus ENSFCAP00000057356 49.6815 31.051 ENSG00000271425 homo_sapiens ENSP00000463957 1.15942 0.816864 ursus_americanus ENSUAMP00000000610 51.1628 36.0465 ENSG00000271425 homo_sapiens ENSP00000463957 1.15942 0.816864 ursus_americanus ENSUAMP00000003393 51.1628 36.0465 ENSG00000271425 homo_sapiens ENSP00000463957 1.15942 0.816864 ursus_americanus ENSUAMP00000002325 51.1628 36.0465 ENSG00000271425 homo_sapiens ENSP00000463957 1.02767 0.764163 bison_bison_bison ENSBBBP00000011329 60 44.6154 ENSG00000271425 homo_sapiens ENSP00000463957 1.13307 0.737813 ovis_aries_rambouillet ENSOARP00020003177 61.4286 40 ENSG00000271425 homo_sapiens ENSP00000463957 1.08037 0.764163 ovis_aries_rambouillet ENSOARP00020003130 58.5714 41.4286 ENSG00000271425 homo_sapiens ENSP00000463957 1.13307 0.737813 ovis_aries_rambouillet ENSOARP00020003168 61.4286 40 ENSG00000271425 homo_sapiens ENSP00000463957 0.974967 0.685112 ovis_aries_rambouillet ENSOARP00020007680 56.0606 39.3939 ENSG00000271425 homo_sapiens ENSP00000463957 1.13307 0.737813 ovis_aries_rambouillet ENSOARP00020003160 61.4286 40 ENSG00000271425 homo_sapiens ENSP00000463957 1.29117 0.790514 ovis_aries_rambouillet ENSOARP00020003165 53.8462 32.967 ENSG00000271425 homo_sapiens ENSP00000463957 1.10672 0.764163 ovis_aries_rambouillet ENSOARP00020003196 60 41.4286 ENSG00000271425 homo_sapiens ENSP00000463957 1.08037 0.685112 ovis_aries_rambouillet ENSOARP00020023801 58.5714 37.1429 ENSG00000271425 homo_sapiens ENSP00000463957 1.10672 0.711462 ovis_aries_rambouillet ENSOARP00020003234 60 38.5714 ENSG00000271425 homo_sapiens ENSP00000463957 2.79315 1.81818 ovis_aries_rambouillet ENSOARP00020003245 51.9608 33.8235 ENSG00000271425 homo_sapiens ENSP00000463957 1.00132 0.737813 ovis_aries_rambouillet ENSOARP00020029618 57.5758 42.4242 ENSG00000271425 homo_sapiens ENSP00000463957 1.08037 0.711462 ovis_aries_rambouillet ENSOARP00020003155 58.5714 38.5714 ENSG00000271425 homo_sapiens ENSP00000463957 1.52833 1.02767 ursus_maritimus ENSUMAP00000013051 63.0435 42.3913 ENSG00000271425 homo_sapiens ENSP00000463957 1.21212 0.869565 ursus_maritimus ENSUMAP00000034736 54.1176 38.8235 ENSG00000271425 homo_sapiens ENSP00000463957 6.71937 4.69038 mustela_putorius_furo ENSMPUP00000002679 44.8944 31.338 ENSG00000271425 homo_sapiens ENSP00000463957 2.39789 1.68643 mustela_putorius_furo ENSMPUP00000002962 47.8947 33.6842 ENSG00000271425 homo_sapiens ENSP00000463957 10.3821 8.88011 chlorocebus_sabaeus ENSCSAP00000016277 83.6518 71.5499 ENSG00000271425 homo_sapiens ENSP00000463957 5.16469 3.61001 tupaia_belangeri ENSTBEP00000002484 31.8699 22.2764 ENSG00000271425 homo_sapiens ENSP00000463957 4.53228 3.00395 tupaia_belangeri ENSTBEP00000012720 30.1754 20 ENSG00000271425 homo_sapiens ENSP00000463957 4.50593 3.10935 tupaia_belangeri ENSTBEP00000000588 51.0448 35.2239 ENSG00000271425 homo_sapiens ENSP00000463957 1.76548 1.18577 camelus_dromedarius ENSCDRP00005002570 65.0485 43.6893 ENSG00000271425 homo_sapiens ENSP00000463957 1.08037 0.843215 prolemur_simus ENSPSMP00000021926 60.2941 47.0588 ENSG00000271425 homo_sapiens ENSP00000463957 3.05665 1.94993 bos_mutus ENSBMUP00000011966 54.2056 34.5794 ENSG00000271425 homo_sapiens ENSP00000463957 1.02767 0.764163 bos_taurus ENSBTAP00000073775 60 44.6154 ENSG00000271425 homo_sapiens ENSP00000463957 4.16337 2.79315 bos_taurus ENSBTAP00000023034 51.634 34.6405 ENSG00000271425 homo_sapiens ENSP00000463957 1.42292 1.00132 sciurus_vulgaris ENSSVLP00005002655 55.102 38.7755 ENSG00000271425 homo_sapiens ENSP00000463957 3.0303 2.08169 bos_grunniens ENSBGRP00000016998 52.9954 36.4055 ENSG00000271425 homo_sapiens ENSP00000463957 13.307 12.1212 rhinopithecus_roxellana ENSRROP00000027953 85.8844 78.2313 ENSG00000271425 homo_sapiens ENSP00000463957 4.00527 3.34651 astyanax_mexicanus ENSAMXP00000050375 74.1463 61.9512
Go ID
Go term
No. evidence
Entries
Species
Category
GO:0003723 enables RNA binding 1 HDA Homo_sapiens(9606) Function GO:0005737 located_in cytoplasm 1 IEA Homo_sapiens(9606) Component
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