Functions and Diseases

RBP Type Canonical_RBPs
Diseases Cancer
Drug N.A.
Main interacting RNAs N.A.
Moonlighting functions TF
Localizations N.A.
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000269343 Gene ID 100293516 Accession 37142
Symbol ZNF587B Alias NA Full Name zinc finger protein 587B
Status Confidence Length 26518 bases Strand Plus strand
Position 19 : 57819721 - 57846238 RNA binding domain zf-met
Summary Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000472004 zf-met PF12874 2.8e-06 1
ENSP00000499083 zf-met PF12874 1.2e-05 1
ENSP00000469623 zf-met PF12874 1.2e-05 1
ENSP00000392410 zf-met PF12874 0.00077 1

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal

Transcripts

Name Transcript ID bp Protein Translation ID
ZNF587B-204 ENST00000651253 3003 632aa ENSP00000499083
ZNF587B-202 ENST00000594328 1670 431aa ENSP00000472004
ZNF587B-201 ENST00000442832 3339 402aa ENSP00000392410
ZNF587B-203 ENST00000594901 5794 633aa ENSP00000469623

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000269343homo_sapiensENSP0000032460561.027246.5257homo_sapiensENSP0000046962331.911524.3286
ENSG00000269343homo_sapiensENSP0000048718347.536935.468homo_sapiensENSP0000046962330.489722.7488
ENSG00000269343homo_sapiensENSP0000050283922.428712.8872homo_sapiensENSP0000046962328.59416.4297
ENSG00000269343homo_sapiensENSP0000036706915.124710.4586homo_sapiensENSP0000046962329.699820.5371
ENSG00000269343homo_sapiensENSP0000038509950.474736.8671homo_sapiensENSP0000046962350.394936.8088
ENSG00000269343homo_sapiensENSP0000022173551.568640.3922homo_sapiensENSP0000046962341.548232.5434
ENSG00000269343homo_sapiensENSP0000015509322.471914.1074homo_sapiensENSP0000046962328.43617.8515
ENSG00000269343homo_sapiensENSP0000030498522.111813.6646homo_sapiensENSP0000046962328.120117.3776
ENSG00000269343homo_sapiensENSP0000037945163.609556.5089homo_sapiensENSP0000046962367.930560.3475
ENSG00000269343homo_sapiensENSP0000047771639.478327.1304homo_sapiensENSP0000046962335.86124.6446
ENSG00000269343homo_sapiensENSP0000038155618.843111.6564homo_sapiensENSP0000046962333.965221.0111
ENSG00000269343homo_sapiensENSP0000032620021.272613.9601homo_sapiensENSP0000046962335.38723.2227
ENSG00000269343homo_sapiensENSP0000028229655.820942.0896homo_sapiensENSP0000046962359.083744.5498
ENSG00000269343homo_sapiensENSP0000028230858.213745.933homo_sapiensENSP0000046962357.661945.4976
ENSG00000269343homo_sapiensENSP0000034899262.276850.8929homo_sapiensENSP0000046962344.075836.019
ENSG00000269343homo_sapiensENSP0000050720655.835246.4531homo_sapiensENSP0000046962338.546632.0695
ENSG00000269343homo_sapiensENSP0000037946456.440344.4965homo_sapiensENSP0000046962338.072730.0158
ENSG00000269343homo_sapiensENSP0000038392243.506531.1688homo_sapiensENSP0000046962331.753622.7488
ENSG00000269343homo_sapiensENSP0000047175448.224336.6355homo_sapiensENSP0000046962340.758330.9637
ENSG00000269343homo_sapiensENSP0000035788125.53715.5131homo_sapiensENSP0000046962316.903610.2686
ENSG00000269343homo_sapiensENSP0000033755556.330343.8532homo_sapiensENSP0000046962348.499237.7567
ENSG00000269343homo_sapiensENSP0000037945867.910453.7313homo_sapiensENSP0000046962343.12834.1232
ENSG00000269343homo_sapiensENSP0000047286760.164345.9959homo_sapiensENSP0000046962346.287535.387
ENSG00000269343homo_sapiensENSP0000047147843.691230.8851homo_sapiensENSP0000046962336.650925.9084
ENSG00000269343homo_sapiensENSP0000033154054.104539.5522homo_sapiensENSP0000046962345.813633.4913
ENSG00000269343homo_sapiensENSP0000036540749.687540.1562homo_sapiensENSP0000046962350.23740.6003
ENSG00000269343homo_sapiensENSP0000030172722.066314.5408homo_sapiensENSP0000046962327.330218.0095
ENSG00000269343homo_sapiensENSP0000028229260.407247.0588homo_sapiensENSP0000046962342.180132.8594
ENSG00000269343homo_sapiensENSP0000028228652.200342.4886homo_sapiensENSP0000046962354.344444.2338
ENSG00000269343homo_sapiensENSP0000030675655.819540.8551homo_sapiensENSP0000046962337.124827.1722
ENSG00000269343homo_sapiensENSP0000050713926.845619.8466homo_sapiensENSP0000046962344.233832.7014
ENSG00000269343homo_sapiensENSP0000038850251.669637.2583homo_sapiensENSP0000046962346.445533.4913
ENSG00000269343homo_sapiensENSP0000036244653.815340.3614homo_sapiensENSP0000046962342.338131.7536
ENSG00000269343homo_sapiensENSP0000041073446.244133.0986homo_sapiensENSP0000046962331.121622.2749
ENSG00000269343homo_sapiensENSP0000030391546.296333.9506homo_sapiensENSP0000046962335.54526.0664
ENSG00000269343homo_sapiensENSP0000044545142.67131.759homo_sapiensENSP0000046962341.390230.8057
ENSG00000269343homo_sapiensENSP0000049891352.063535.5556homo_sapiensENSP0000046962325.908417.6935
ENSG00000269343homo_sapiensENSP0000037558289.926387.715homo_sapiensENSP0000046962357.819956.3981

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000269343homo_sapiensENSP0000046962397.314496.2085pan_paniscusENSPPAP0000000761797.933296.8204
ENSG00000269343homo_sapiensENSP0000046962396.524595.5766gorilla_gorillaENSGGOP0000000013694.875893.9441
ENSG00000269343homo_sapiensENSP0000046962326.698318.7994sarcophilus_harrisiiENSSHAP0000004183132.688623.0174
ENSG00000269343homo_sapiensENSP0000046962326.856220.8531vulpes_vulpesENSVVUP0000000827733.530626.0355
ENSG00000269343homo_sapiensENSP0000046962327.488219.9052equus_asinusENSEASP0000505176537.100226.8657
ENSG00000269343homo_sapiensENSP0000046962325.276518.3254panthera_leoENSPLOP0000002420030.828522.3507
ENSG00000269343homo_sapiensENSP0000046962323.222716.7457equus_caballusENSECAP0000001021727.071819.5212
ENSG00000269343homo_sapiensENSP0000046962322.906817.0616canis_lupus_familiarisENSCAFP0084500391326.802219.963
ENSG00000269343homo_sapiensENSP0000046962320.695114.8499balaenoptera_musculusENSBMSP0001000266425.486418.2879
ENSG00000269343homo_sapiensENSP0000046962335.86125.1185felis_catusENSFCAP0000005540622.519815.7738
ENSG00000269343homo_sapiensENSP0000046962337.440826.5403monodelphis_domesticaENSMODP0000002415522.507115.9544
ENSG00000269343homo_sapiensENSP0000046962326.066417.5355mus_musculusENSMUSP0000013959121.235514.2857
ENSG00000269343homo_sapiensENSP0000046962326.856218.0095mus_musculusENSMUSP0000014060021.739114.578
ENSG00000269343homo_sapiensENSP0000046962335.38733.0174chlorocebus_sabaeusENSCSAP0000001915789.24383.2669
ENSG00000269343homo_sapiensENSP0000046962327.330218.0095rattus_norvegicusENSRNOP0000007279322.151114.5967
ENSG00000269343homo_sapiensENSP0000046962344.075836.6509prolemur_simusENSPSMP0000002533668.550457.0025
ENSG00000269343homo_sapiensENSP0000046962337.756726.6983vombatus_ursinusENSVURP0001000429222.675516.0342
ENSG00000269343homo_sapiensENSP0000046962320.221212.3223vombatus_ursinusENSVURP0001001729834.688321.1382
ENSG00000269343homo_sapiensENSP0000046962353.712551.1848rhinopithecus_bietiENSRBIP0000003953486.734782.6531
ENSG00000269343homo_sapiensENSP0000046962335.071124.6446canis_lupus_dingoENSCAFP0002002028423.442416.4731
ENSG00000269343homo_sapiensENSP000004696237.424962.8436phascolarctos_cinereusENSPCIP000000531749.690723.71134
ENSG00000269343homo_sapiensENSP0000046962344.233836.4929cervus_hanglu_yarkandensisENSCHYP0000000923068.627456.6176
ENSG00000269343homo_sapiensENSP0000046962373.617766.6667rhinopithecus_roxellanaENSRROP0000002725985.19277.1481
ENSG00000269343homo_sapiensENSP0000046962319.905213.5861petromyzon_marinusENSPMAP0000000304324.561416.7641
ENSG00000269343homo_sapiensENSP0000046962322.116914.8499eptatretus_burgeriENSEBUP0000001889526.717617.9389
ENSG00000269343homo_sapiensENSP0000046962325.908416.5877eptatretus_burgeriENSEBUP0000001796824.368515.6018
ENSG00000269343homo_sapiensENSP0000046962319.115313.4281eptatretus_burgeriENSEBUP0000002342723.404316.441
ENSG00000269343homo_sapiensENSP0000046962325.908415.7978lepisosteus_oculatusENSLOCP0000000395021.437913.0719
ENSG00000269343homo_sapiensENSP0000046962326.540315.1659clupea_harengusENSCHAP0000001826722.702712.973
ENSG00000269343homo_sapiensENSP0000046962323.696714.218clupea_harengusENSCHAP0000001077017.543910.5263
ENSG00000269343homo_sapiensENSP0000046962326.382315.4818danio_rerioENSDARP0000009944522.598113.2612
ENSG00000269343homo_sapiensENSP0000046962325.276514.376danio_rerioENSDARP0000014088822.346412.7095
ENSG00000269343homo_sapiensENSP0000046962325.908414.534carassius_auratusENSCARP0000010806922.651912.7072
ENSG00000269343homo_sapiensENSP0000046962325.750414.8499carassius_auratusENSCARP0000013209122.328812.8767
ENSG00000269343homo_sapiensENSP0000046962324.960514.218carassius_auratusENSCARP0000004716621.614212.3119
ENSG00000269343homo_sapiensENSP0000046962325.750414.534carassius_auratusENSCARP0000010195121.791412.2995
ENSG00000269343homo_sapiensENSP0000046962324.960514.218carassius_auratusENSCARP0000009443121.614212.3119
ENSG00000269343homo_sapiensENSP0000046962326.066414.8499astyanax_mexicanusENSAMXP0000005093422.44912.7891
ENSG00000269343homo_sapiensENSP0000046962325.592415.1659astyanax_mexicanusENSAMXP0000000707422.252713.1868
ENSG00000269343homo_sapiensENSP0000046962325.434414.6919ictalurus_punctatusENSIPUP0000001028722.054812.7397
ENSG00000269343homo_sapiensENSP0000046962324.328614.376ictalurus_punctatusENSIPUP0000003135519.617811.5924
ENSG00000269343homo_sapiensENSP0000046962326.382315.3239esox_luciusENSELUP0000004076922.537113.0904
ENSG00000269343homo_sapiensENSP0000046962324.644614.376electrophorus_electricusENSEEEP0000004304421.517212.5517
ENSG00000269343homo_sapiensENSP0000046962325.592415.6398electrophorus_electricusENSEEEP0000000239822.252713.5989
ENSG00000269343homo_sapiensENSP0000046962325.750414.8499oncorhynchus_kisutchENSOKIP0000508795822.02712.7027
ENSG00000269343homo_sapiensENSP0000046962325.908414.8499oncorhynchus_kisutchENSOKIP0000510365922.589512.9477
ENSG00000269343homo_sapiensENSP0000046962326.066414.8499oncorhynchus_mykissENSOMYP0000010341922.69612.9298
ENSG00000269343homo_sapiensENSP0000046962325.750414.8499oncorhynchus_mykissENSOMYP0000010555522.02712.7027
ENSG00000269343homo_sapiensENSP0000046962326.066414.8499salmo_salarENSSSAP0000017726822.69612.9298
ENSG00000269343homo_sapiensENSP0000046962325.750414.8499salmo_salarENSSSAP0000016948022.02712.7027
ENSG00000269343homo_sapiensENSP0000046962326.066414.8499salmo_truttaENSSTUP0000001415122.758612.9655
ENSG00000269343homo_sapiensENSP0000046962325.750414.8499salmo_truttaENSSTUP0000010766122.02712.7027
ENSG00000269343homo_sapiensENSP0000046962325.592415.0079gadus_morhuaENSGMOP0000006726922.040812.9252
ENSG00000269343homo_sapiensENSP0000046962316.429710.2686fundulus_heteroclitusENSFHEP0000000521834.098421.3115
ENSG00000269343homo_sapiensENSP000004696235.68723.00158fundulus_heteroclitusENSFHEP0000003009812.7666.73759
ENSG00000269343homo_sapiensENSP0000046962324.960514.6919xiphophorus_maculatusENSXMAP0000001302222.539213.2668
ENSG00000269343homo_sapiensENSP0000046962325.118514.6919oryzias_latipesENSORLP0000003140122.489413.1542
ENSG00000269343homo_sapiensENSP0000046962324.802514.6919cyclopterus_lumpusENSCLMP0000503030422.396613.2668
ENSG00000269343homo_sapiensENSP0000046962325.908414.6919oreochromis_niloticusENSONIP0000003302621.954512.4498
ENSG00000269343homo_sapiensENSP0000046962325.908414.6919haplochromis_burtoniENSHBUP0000003414021.954512.4498
ENSG00000269343homo_sapiensENSP0000046962325.908414.6919astatotilapia_callipteraENSACLP0000002728121.954512.4498
ENSG00000269343homo_sapiensENSP0000046962325.750414.8499sparus_aurataENSSAUP0001000349121.849912.6005
ENSG00000269343homo_sapiensENSP0000046962325.908414.8499lates_calcariferENSLCAP0001001554221.983912.6005
ENSG00000269343homo_sapiensENSP0000046962327.488217.0616xenopus_tropicalisENSXETP0000001700421.94213.6192
ENSG00000269343homo_sapiensENSP0000046962322.432915.0079meleagris_gallopavoENSMGAP0000001551830.802620.6074
ENSG00000269343homo_sapiensENSP0000046962324.802513.9021neolamprologus_brichardiENSNBRP0000002931722.332912.5178
ENSG00000269343homo_sapiensENSP0000046962327.172216.1137erpetoichthys_calabaricusENSECRP0000000884521.662512.8463
ENSG00000269343homo_sapiensENSP0000046962324.802514.534kryptolebias_marmoratusENSKMAP0000002457222.23813.0312
ENSG00000269343homo_sapiensENSP0000046962324.012613.9021oryzias_javanicusENSOJAP0000003200523.49313.6012
ENSG00000269343homo_sapiensENSP0000046962325.592414.6919amphilophus_citrinellusENSACIP0000000254122.283412.7923
ENSG00000269343homo_sapiensENSP0000046962325.908414.8499dicentrarchus_labraxENSDLAP0000500995921.983912.6005
ENSG00000269343homo_sapiensENSP0000046962325.908414.6919amphiprion_perculaENSAPEP0000003451021.983912.4665
ENSG00000269343homo_sapiensENSP0000046962325.118514.534oryzias_sinensisENSOSIP0000002032822.746813.1617
ENSG00000269343homo_sapiensENSP0000046962325.908414.8499seriola_dumeriliENSSDUP0000000929821.983912.6005
ENSG00000269343homo_sapiensENSP0000046962324.644614.06cottoperca_gobioENSCGOP0000000359922.543412.8613
ENSG00000269343homo_sapiensENSP0000046962322.748812.3223gasterosteus_aculeatusENSGACP0000002734619.672110.6557
ENSG00000269343homo_sapiensENSP0000046962324.802514.6919cynoglossus_semilaevisENSCSEP0000002980522.050613.0618
ENSG00000269343homo_sapiensENSP0000046962325.434414.6919poecilia_formosaENSPFOP0000001942322.580613.0435
ENSG00000269343homo_sapiensENSP0000046962326.224315.0079myripristis_murdjanENSMMDP0000501566822.222212.7175
ENSG00000269343homo_sapiensENSP0000046962325.908414.8499sander_luciopercaENSSLUP0000005222121.837512.5166
ENSG00000269343homo_sapiensENSP0000046962325.908414.6919amphiprion_ocellarisENSAOCP0000003182121.983912.4665
ENSG00000269343homo_sapiensENSP0000046962325.750414.8499hucho_huchoENSHHUP0000005688822.086712.7371
ENSG00000269343homo_sapiensENSP0000046962326.066414.8499hucho_huchoENSHHUP0000008732722.821613.0014
ENSG00000269343homo_sapiensENSP0000046962325.908414.8499betta_splendensENSBSLP0000005642321.983912.6005
ENSG00000269343homo_sapiensENSP0000046962326.224315.6398pygocentrus_nattereriENSPNAP0000001180521.899713.0607
ENSG00000269343homo_sapiensENSP0000046962325.908415.0079pygocentrus_nattereriENSPNAP0000001251621.21612.2898
ENSG00000269343homo_sapiensENSP0000046962325.908414.8499anabas_testudineusENSATEP0000002552821.983912.6005
ENSG00000269343homo_sapiensENSP0000046962325.908414.8499seriola_lalandi_dorsalisENSSLDP0000002507721.983912.6005
ENSG00000269343homo_sapiensENSP0000046962324.802514.534labrus_bergyltaENSLBEP0000000499522.396613.1241
ENSG00000269343homo_sapiensENSP0000046962324.960514.534pundamilia_nyerereiENSPNYP0000001923222.507113.1054
ENSG00000269343homo_sapiensENSP0000046962325.908414.8499mastacembelus_armatusENSMAMP0000002637721.954512.5837
ENSG00000269343homo_sapiensENSP0000046962325.908414.6919stegastes_partitusENSSPAP0000000385621.983912.4665
ENSG00000269343homo_sapiensENSP0000046962325.750414.8499oncorhynchus_tshawytschaENSOTSP0000508296322.02712.7027
ENSG00000269343homo_sapiensENSP0000046962326.066414.8499oncorhynchus_tshawytschaENSOTSP0000502063022.69612.9298
ENSG00000269343homo_sapiensENSP0000046962325.908414.8499acanthochromis_polyacanthusENSAPOP0000000532021.983912.6005
ENSG00000269343homo_sapiensENSP0000046962324.486614.534nothobranchius_furzeriENSNFUP0001505060822.079813.1054
ENSG00000269343homo_sapiensENSP0000046962324.960514.6919cyprinodon_variegatusENSCVAP0000001543322.603713.3047
ENSG00000269343homo_sapiensENSP0000046962325.592415.1659denticeps_clupeoidesENSDCDP0000006330822.689113.4454
ENSG00000269343homo_sapiensENSP0000046962325.750415.1659denticeps_clupeoidesENSDCDP0000003546721.589412.7152
ENSG00000269343homo_sapiensENSP0000046962325.750414.534larimichthys_croceaENSLCRP0000501776421.849912.3324
ENSG00000269343homo_sapiensENSP0000046962325.276514.6919takifugu_rubripesENSTRUP0000004332322.824513.2668
ENSG00000269343homo_sapiensENSP0000046962325.434414.534hippocampus_comesENSHCOP0000002831222.361112.7778
ENSG00000269343homo_sapiensENSP0000046962325.908414.6919cyprinus_carpio_carpioENSCCRP0000014761521.954512.4498
ENSG00000269343homo_sapiensENSP0000046962326.066415.1659cyprinus_carpio_carpioENSCCRP0000010867322.602713.1507
ENSG00000269343homo_sapiensENSP0000046962325.434414.534cyprinus_carpio_carpioENSCCRP0000003879221.352812.2016
ENSG00000269343homo_sapiensENSP0000046962326.066414.6919cyprinus_carpio_carpioENSCCRP0000011456722.758612.8276
ENSG00000269343homo_sapiensENSP0000046962324.644614.534poecilia_latipinnaENSPLAP0000000516723.853214.0673
ENSG00000269343homo_sapiensENSP0000046962325.434414.6919sinocyclocheilus_grahamiENSSGRP0000005353523.032913.3047
ENSG00000269343homo_sapiensENSP0000046962326.382315.3239sinocyclocheilus_grahamiENSSGRP0000006898422.876713.2877
ENSG00000269343homo_sapiensENSP0000046962324.802514.376sinocyclocheilus_grahamiENSSGRP0000008182422.143912.835
ENSG00000269343homo_sapiensENSP0000046962325.118514.218sinocyclocheilus_grahamiENSSGRP0000008902221.428612.1294
ENSG00000269343homo_sapiensENSP0000046962325.908414.6919maylandia_zebraENSMZEP0000502460121.954512.4498
ENSG00000269343homo_sapiensENSP0000046962324.486614.376tetraodon_nigroviridisENSTNIP0000001291925.121614.7488
ENSG00000269343homo_sapiensENSP0000046962322.748814.8499paramormyrops_kingsleyaeENSPKIP0000001048619.69912.8591
ENSG00000269343homo_sapiensENSP0000046962322.116912.7962paramormyrops_kingsleyaeENSPKIP0000001182121.212112.2727
ENSG00000269343homo_sapiensENSP0000046962325.592415.4818scleropages_formosusENSSFOP0001504320022.10113.3697
ENSG00000269343homo_sapiensENSP0000046962324.960514.6919scleropages_formosusENSSFOP0001502118621.763112.8099
ENSG00000269343homo_sapiensENSP0000046962327.962117.3776leptobrachium_leishanenseENSLLEP0000004600822.376713.9064
ENSG00000269343homo_sapiensENSP0000046962325.750414.6919scophthalmus_maximusENSSMAP0000002033221.849912.4665
ENSG00000269343homo_sapiensENSP0000046962324.802514.6919oryzias_melastigmaENSOMEP0000002014222.301113.2102

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0000122involved_in negative regulation of transcription by RNA polymerase II1IBAHomo_sapiens(9606)Process
GO:0000977enables RNA polymerase II transcription regulatory region sequence-specific DNA binding1IBAHomo_sapiens(9606)Function
GO:0001227enables DNA-binding transcription repressor activity, RNA polymerase II-specific1IBAHomo_sapiens(9606)Function
GO:0005634located_in nucleus1IEAHomo_sapiens(9606)Component
GO:0046872enables metal ion binding1IEAHomo_sapiens(9606)Function

Expression