RBP Type	Canonical_RBPs
Diseases	N.A.
Drug	N.A.
Main interacting RNAs	N.A.
Moonlighting functions	N.A.
Localizations	Nucleoli
BulkPerturb-seq

Ensembl ID	ENSG00000258659	Gene ID	53840	Accession	10063
Symbol	TRIM34	Alias	IFP1;RNF21	Full Name	tripartite motif containing 34
Status	Confidence	Length	24635 bases	Strand	Plus strand
Position	11 : 5619764 - 5644398	RNA binding domain	SPRY
Summary	The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, B-box type 1 and B-box type 2 domain, and a coiled-coil region. Expression of this gene is up-regulated by interferon. This gene is mapped to chromosome 11p15, where it resides within a TRIM gene cluster. Alternative splicing results in multiple transcript variants. A read-through transcript from the upstream TRIM6 gene has also been observed, which results in a fusion product from these neighboring family members. [provided by RefSeq, Oct 2010]

Protein	Domain	Pfam ID	E-value	Domain number
ENSP00000402595	SPRY	PF00622	1.1e-09	1
ENSP00000422947	SPRY	PF00622	1.1e-09	1

Pubmed ID	Full Name	Cell	Author	Time	Doi

Pubmed ID	Title	Author	Time	Journal

Name	Transcript ID	bp	Protein	Translation ID
TRIM34-204	ENST00000514226	2493	488aa	ENSP00000422947
TRIM34-201	ENST00000429814	2293	488aa	ENSP00000402595
TRIM34-202	ENST00000491385	933	No protein	-
TRIM34-203	ENST00000495668	851	No protein	-

Pathway ID	Pathway Name	Source

ensgID	Trait	pValue	Pubmed ID
18661	Erythrocyte Indices	6.686e-005	-
85276	Cognition Disorders	8E-10	26252872
85278	Cognitive Dysfunction	8E-10	26252872
88825	Cognition Disorders	9E-9	26252872
88827	Cognitive Dysfunction	9E-9	26252872

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0000209	involved_in protein polyubiquitination	1	IBA	Homo_sapiens(9606)	Process
GO:0003674	enables molecular_function	1	ND	Homo_sapiens(9606)	Function
GO:0005654	is_active_in nucleoplasm	1	IBA	Homo_sapiens(9606)	Component
GO:0005737	is_active_in cytoplasm	2	IBA,IDA	Homo_sapiens(9606)	Component
GO:0005739	located_in mitochondrion	1	IEA	Homo_sapiens(9606)	Component
GO:0005829	is_active_in cytosol	2	IBA,TAS	Homo_sapiens(9606)	Component
GO:0008270	enables zinc ion binding	1	IEA	Homo_sapiens(9606)	Function
GO:0010508	involved_in positive regulation of autophagy	1	IBA	Homo_sapiens(9606)	Process
GO:0019901	enables protein kinase binding	1	IBA	Homo_sapiens(9606)	Function
GO:0032880	involved_in regulation of protein localization	1	IBA	Homo_sapiens(9606)	Process
GO:0042802	enables identical protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0042803	enables protein homodimerization activity	1	IBA	Homo_sapiens(9606)	Function
GO:0043123	involved_in positive regulation of I-kappaB kinase/NF-kappaB signaling	1	IBA	Homo_sapiens(9606)	Process
GO:0045087	involved_in innate immune response	1	IBA	Homo_sapiens(9606)	Process
GO:0046596	involved_in regulation of viral entry into host cell	1	IBA	Homo_sapiens(9606)	Process
GO:0051091	involved_in positive regulation of DNA-binding transcription factor activity	1	IDA	Homo_sapiens(9606)	Process
GO:0051092	involved_in positive regulation of NF-kappaB transcription factor activity	1	IBA	Homo_sapiens(9606)	Process
GO:0051607	involved_in defense response to virus	1	IEA	Homo_sapiens(9606)	Process
GO:0061630	enables ubiquitin protein ligase activity	1	IBA	Homo_sapiens(9606)	Function