RBP Type	Canonical_RBPs
Diseases	Cancer Disease
Drug	N.A.
Main interacting RNAs	N.A.
Moonlighting functions	Metabolic enzyme
Localizations	N.A.
BulkPerturb-seq	N.A.

Ensembl ID	ENSG00000258366	Gene ID	51750	Accession	15888
Symbol	RTEL1	Alias	NHL;RTEL;DKCA4;DKCB5;PFBMFT3;C20orf41	Full Name	regulator of telomere elongation helicase 1
Status	Confidence	Length	38444 bases	Strand	Plus strand
Position	20 : 63657810 - 63696253	RNA binding domain	ResIII
Summary	This gene encodes a DNA helicase which functions in the stability, protection and elongation of telomeres and interacts with proteins in the shelterin complex known to protect telomeres during DNA replication. Mutations in this gene have been associated with dyskeratosis congenita and Hoyerall-Hreidarsson syndrome. Read-through transcription of this gene into the neighboring downstream gene, which encodes tumor necrosis factor receptor superfamily, member 6b, generates a non-coding transcript. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2013]

Protein	Domain	Pfam ID	E-value	Domain number
ENSP00000494280	ResIII	PF04851	4.4e-05	1
ENSP00000513448	ResIII	PF04851	7.1e-05	1
ENSP00000513449	ResIII	PF04851	7.1e-05	1

Pubmed ID	Full Name	Cell	Author	Time	Doi

Pubmed ID	Title	Author	Time	Journal
34021146	RTEL1 influences the abundance and localization of TERRA RNA.	Fiorella Ghisays	2021-05-21	Nature communications
37046839	R-Loops at Chromosome Ends: From Formation, Regulation, and Cellular Consequence.	Yi Gong	2023-04-06	Cancers

Name	Transcript ID	bp	Protein	Translation ID
RTEL1-205	ENST00000370018	4955	1219aa	ENSP00000359035
RTEL1-208	ENST00000469728	601	48aa	ENSP00000496027
RTEL1-219	ENST00000692658	1859	109aa	ENSP00000513448
RTEL1-216	ENST00000684971	1714	109aa	ENSP00000513449
RTEL1-217	ENST00000686756	2398	No protein	-
RTEL1-203	ENST00000360203	4615	1300aa	ENSP00000353332
RTEL1-212	ENST00000508582	4517	1243aa	ENSP00000424307
RTEL1-201	ENST00000318100	4162	996aa	ENSP00000322287
RTEL1-209	ENST00000482936	3474	1004aa	ENSP00000457868
RTEL1-202	ENST00000356810	1339	356aa	ENSP00000349265
RTEL1-210	ENST00000488316	685	No protein	-
RTEL1-214	ENST00000646389	570	89aa	ENSP00000494280
RTEL1-220	ENST00000692911	2127	No protein	-
RTEL1-218	ENST00000687123	1891	17aa	ENSP00000513450
RTEL1-206	ENST00000425905	2012	No protein	-
RTEL1-213	ENST00000645309	331	No protein	-
RTEL1-207	ENST00000463361	575	No protein	-
RTEL1-215	ENST00000647249	457	No protein	-
RTEL1-221	ENST00000697814	508	No protein	-
RTEL1-211	ENST00000496816	2222	316aa	ENSP00000425576
RTEL1-204	ENST00000370003	2273	No protein	-

Pathway ID	Pathway Name	Source

ensgID	Trait	pValue	Pubmed ID
34310	Smoking	8.7600000E-006	-
34570	Platelet Function Tests	2.3900000E-007	-
35543	Platelet Function Tests	8.7400000E-006	-
56338	Glioma	1.4930000E-007	-
56353	Glioma	1.1290000E-010	-
56355	Glioma	3.8930000E-010	-
65197	Glioma	9E-11	26424050
65255	Dermatitis, Atopic	2E-9	26482879
66172	Colitis, Ulcerative	2E-10	21297633
76665	Glioma	2E-9	21531791
78190	Dental Caries	3E-6	23259602
83387	Glioma	5E-19	24908248
89675	Dermatitis, Atopic	7E-13	26482879
96535	Glioblastoma	1E-13	26424050
96992	Glioma	2E-9	19578366
97412	Glioma	3E-9	19578366
97449	Glioma	3E-12	19578367
98780	Glioma	1E-10	22886559

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSG00000258366	homo_sapiens	ENSP00000259008	37.3098	23.1385	homo_sapiens	ENSP00000353332	35.8462	22.2308
ENSG00000258366	homo_sapiens	ENSP00000375809	43.2895	26.5789	homo_sapiens	ENSP00000353332	25.3077	15.5385
ENSG00000258366	homo_sapiens	ENSP00000443426	38.521	24.2826	homo_sapiens	ENSP00000353332	26.8462	16.9231

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSG00000258366	homo_sapiens	ENSP00000353332	91.9231	90.6923	nomascus_leucogenys	ENSNLEP00000045830	90.8055	89.5897
ENSG00000258366	homo_sapiens	ENSP00000353332	97.4615	96.6154	pan_paniscus	ENSPPAP00000029813	96.1305	95.2959
ENSG00000258366	homo_sapiens	ENSP00000353332	96.2308	95	pan_troglodytes	ENSPTRP00000076045	95.0608	93.845
ENSG00000258366	homo_sapiens	ENSP00000353332	96.2308	95	pan_troglodytes	ENSPTRP00000066223	95.0608	93.845
ENSG00000258366	homo_sapiens	ENSP00000353332	99.0769	98.6923	gorilla_gorilla	ENSGGOP00000018446	99.0008	98.6164
ENSG00000258366	homo_sapiens	ENSP00000353332	76.3077	65.2308	ornithorhynchus_anatinus	ENSOANP00000007825	75.9571	64.9311
ENSG00000258366	homo_sapiens	ENSP00000353332	74.6923	62.8462	sarcophilus_harrisii	ENSSHAP00000040535	74.1221	62.3664
ENSG00000258366	homo_sapiens	ENSP00000353332	48.6923	40.5385	notamacropus_eugenii	ENSMEUP00000002902	50.7212	42.2276
ENSG00000258366	homo_sapiens	ENSP00000353332	75.7692	67.3846	dasypus_novemcinctus	ENSDNOP00000022372	77.0133	68.491
ENSG00000258366	homo_sapiens	ENSP00000353332	67.3077	60.3846	erinaceus_europaeus	ENSEEUP00000004902	68.5737	61.5204
ENSG00000258366	homo_sapiens	ENSP00000353332	54.1538	48.3077	echinops_telfairi	ENSETEP00000001760	55.3024	49.3323
ENSG00000258366	homo_sapiens	ENSP00000353332	89.3077	85.8462	callithrix_jacchus	ENSCJAP00000087307	70.9658	68.2152
ENSG00000258366	homo_sapiens	ENSP00000353332	94.3846	93.0769	cercocebus_atys	ENSCATP00000003827	90.7544	89.497
ENSG00000258366	homo_sapiens	ENSP00000353332	93.1538	91.3077	macaca_fascicularis	ENSMFAP00000024350	94.6094	92.7344
ENSG00000258366	homo_sapiens	ENSP00000353332	92.8462	91.4615	macaca_mulatta	ENSMMUP00000000235	93.0609	91.6731
ENSG00000258366	homo_sapiens	ENSP00000353332	93.9231	92.3846	macaca_nemestrina	ENSMNEP00000030955	90.1773	88.7001
ENSG00000258366	homo_sapiens	ENSP00000353332	94.6923	93.1538	papio_anubis	ENSPANP00000047749	93.541	92.0213
ENSG00000258366	homo_sapiens	ENSP00000353332	94	92.7692	mandrillus_leucophaeus	ENSMLEP00000023995	90.4515	89.2672
ENSG00000258366	homo_sapiens	ENSP00000353332	83.0769	76.6154	tursiops_truncatus	ENSTTRP00000011588	78.4314	72.3312
ENSG00000258366	homo_sapiens	ENSP00000353332	75.4615	68.7692	vulpes_vulpes	ENSVVUP00000020585	79.6266	72.5649
ENSG00000258366	homo_sapiens	ENSP00000353332	77.6154	69.8462	mus_spretus	MGP_SPRETEiJ_P0058934	83.4574	75.1034
ENSG00000258366	homo_sapiens	ENSP00000353332	83.0769	76.8462	equus_asinus	ENSEASP00005033874	87.4494	80.8907
ENSG00000258366	homo_sapiens	ENSP00000353332	78.1538	71.4615	capra_hircus	ENSCHIP00000012311	83.8284	76.6502
ENSG00000258366	homo_sapiens	ENSP00000353332	77.9231	69	loxodonta_africana	ENSLAFP00000019150	78.5271	69.5349
ENSG00000258366	homo_sapiens	ENSP00000353332	81.1538	74.3077	panthera_leo	ENSPLOP00000026912	81.0292	74.1936
ENSG00000258366	homo_sapiens	ENSP00000353332	83.3077	75.9231	ailuropoda_melanoleuca	ENSAMEP00000032971	84.6755	77.1697
ENSG00000258366	homo_sapiens	ENSP00000353332	82.3846	75.7692	bos_indicus_hybrid	ENSBIXP00005014952	84.5972	77.8041
ENSG00000258366	homo_sapiens	ENSP00000353332	85.7692	79.2308	equus_caballus	ENSECAP00000056536	85.9014	79.3529
ENSG00000258366	homo_sapiens	ENSP00000353332	82	75.3846	canis_lupus_familiaris	ENSCAFP00845024546	81.6233	75.0383
ENSG00000258366	homo_sapiens	ENSP00000353332	76.6923	70.4615	marmota_marmota_marmota	ENSMMMP00000001762	85.4327	78.4919
ENSG00000258366	homo_sapiens	ENSP00000353332	80.7692	74.6923	balaenoptera_musculus	ENSBMSP00010014012	83.5322	77.2474
ENSG00000258366	homo_sapiens	ENSP00000353332	78.2308	72.3077	cavia_porcellus	ENSCPOP00000012982	81.6212	75.4414
ENSG00000258366	homo_sapiens	ENSP00000353332	78.6154	71.6923	ursus_americanus	ENSUAMP00000011527	78.1943	71.3083
ENSG00000258366	homo_sapiens	ENSP00000353332	72.9231	60.6923	monodelphis_domestica	ENSMODP00000021212	73.947	61.5445
ENSG00000258366	homo_sapiens	ENSP00000353332	78.6923	72.6154	bison_bison_bison	ENSBBBP00000010027	84.7556	78.2104
ENSG00000258366	homo_sapiens	ENSP00000353332	83.9231	77.3077	monodon_monoceros	ENSMMNP00015001477	82.3396	75.8491
ENSG00000258366	homo_sapiens	ENSP00000353332	83.3077	76	sus_scrofa	ENSSSCP00000050925	84.8081	77.3688
ENSG00000258366	homo_sapiens	ENSP00000353332	85.2308	79.6923	microcebus_murinus	ENSMICP00000026531	84.3869	78.9033
ENSG00000258366	homo_sapiens	ENSP00000353332	76.1538	69.0769	octodon_degus	ENSODEP00000009051	84.8329	76.9494
ENSG00000258366	homo_sapiens	ENSP00000353332	78.6154	71.9231	jaculus_jaculus	ENSJJAP00000003090	85.1667	77.9167
ENSG00000258366	homo_sapiens	ENSP00000353332	82.2308	75.7692	ovis_aries_rambouillet	ENSOARP00020004049	84.3725	77.7427
ENSG00000258366	homo_sapiens	ENSP00000353332	71.3077	65.2308	ursus_maritimus	ENSUMAP00000030678	74.5776	68.222
ENSG00000258366	homo_sapiens	ENSP00000353332	57.8462	52.3077	ochotona_princeps	ENSOPRP00000002739	59.9203	54.1833
ENSG00000258366	homo_sapiens	ENSP00000353332	83.7692	77.2308	delphinapterus_leucas	ENSDLEP00000008606	85.0117	78.3763
ENSG00000258366	homo_sapiens	ENSP00000353332	83.6154	77.4615	physeter_catodon	ENSPCTP00005010319	85.5906	79.2913
ENSG00000258366	homo_sapiens	ENSP00000353332	77.6154	69.8462	mus_caroli	MGP_CAROLIEiJ_P0056706	83.8736	75.478
ENSG00000258366	homo_sapiens	ENSP00000353332	77.6923	70	mus_musculus	ENSMUSP00000053120	83.5401	75.2688
ENSG00000258366	homo_sapiens	ENSP00000353332	76.3077	70.9231	dipodomys_ordii	ENSDORP00000022128	84.7139	78.7361
ENSG00000258366	homo_sapiens	ENSP00000353332	81.6154	73.6154	mustela_putorius_furo	ENSMPUP00000008371	83.6091	75.4137
ENSG00000258366	homo_sapiens	ENSP00000353332	88.6154	85.2308	aotus_nancymaae	ENSANAP00000003493	86.9434	83.6226
ENSG00000258366	homo_sapiens	ENSP00000353332	93.2308	90.2308	saimiri_boliviensis_boliviensis	ENSSBOP00000003679	92.8025	89.8162
ENSG00000258366	homo_sapiens	ENSP00000353332	93.6154	91.4615	chlorocebus_sabaeus	ENSCSAP00000012504	86.5576	84.5661
ENSG00000258366	homo_sapiens	ENSP00000353332	82.0769	74.0769	mesocricetus_auratus	ENSMAUP00000025309	84.2812	76.0664
ENSG00000258366	homo_sapiens	ENSP00000353332	83.6154	77.1538	phocoena_sinus	ENSPSNP00000026437	84.8556	78.2982
ENSG00000258366	homo_sapiens	ENSP00000353332	82.3077	76	camelus_dromedarius	ENSCDRP00005014335	86.9212	80.2599
ENSG00000258366	homo_sapiens	ENSP00000353332	84.3846	78.2308	carlito_syrichta	ENSTSYP00000034242	83.4855	77.3973
ENSG00000258366	homo_sapiens	ENSP00000353332	81.6154	73.8462	rattus_norvegicus	ENSRNOP00000051909	83.281	75.3532
ENSG00000258366	homo_sapiens	ENSP00000353332	80.3077	74.2308	prolemur_simus	ENSPSMP00000001520	83.2536	76.9538
ENSG00000258366	homo_sapiens	ENSP00000353332	81	73.3846	microtus_ochrogaster	ENSMOCP00000007004	83.307	75.4747
ENSG00000258366	homo_sapiens	ENSP00000353332	78.4615	71.6154	peromyscus_maniculatus_bairdii	ENSPEMP00000011124	85.5705	78.104
ENSG00000258366	homo_sapiens	ENSP00000353332	78.6923	72.6923	bos_mutus	ENSBMUP00000023144	84.7556	78.2933
ENSG00000258366	homo_sapiens	ENSP00000353332	77.6154	69.8462	mus_spicilegus	ENSMSIP00000015291	83.8736	75.478
ENSG00000258366	homo_sapiens	ENSP00000353332	77.4615	70.0769	cricetulus_griseus_chok1gshd	ENSCGRP00001014212	84.5508	76.4903
ENSG00000258366	homo_sapiens	ENSP00000353332	74	67.3077	pteropus_vampyrus	ENSPVAP00000012721	69.862	63.5439
ENSG00000258366	homo_sapiens	ENSP00000353332	79.5385	73	myotis_lucifugus	ENSMLUP00000004788	84.1334	77.2172
ENSG00000258366	homo_sapiens	ENSP00000353332	75.3846	63.2308	vombatus_ursinus	ENSVURP00010018464	74.8663	62.796
ENSG00000258366	homo_sapiens	ENSP00000353332	82.9231	74.3077	rhinolophus_ferrumequinum	ENSRFEP00010019213	84.2188	75.4688
ENSG00000258366	homo_sapiens	ENSP00000353332	82.0769	73.4615	neovison_vison	ENSNVIP00000024856	84.082	75.2561
ENSG00000258366	homo_sapiens	ENSP00000353332	82.3846	75.7692	bos_taurus	ENSBTAP00000028108	84.5972	77.8041
ENSG00000258366	homo_sapiens	ENSP00000353332	89.1538	87.5385	rhinopithecus_bieti	ENSRBIP00000029291	86.2993	84.7357
ENSG00000258366	homo_sapiens	ENSP00000353332	80	73	canis_lupus_dingo	ENSCAFP00020002237	78.6687	71.7852
ENSG00000258366	homo_sapiens	ENSP00000353332	78.3077	71.6154	sciurus_vulgaris	ENSSVLP00005014355	86.0524	78.6982
ENSG00000258366	homo_sapiens	ENSP00000353332	70	58.0769	phascolarctos_cinereus	ENSPCIP00000023718	74.2251	61.5824
ENSG00000258366	homo_sapiens	ENSP00000353332	65.9231	59.2308	procavia_capensis	ENSPCAP00000010792	63.3407	56.9106
ENSG00000258366	homo_sapiens	ENSP00000353332	82.9231	75	nannospalax_galili	ENSNGAP00000003545	85.0158	76.8927
ENSG00000258366	homo_sapiens	ENSP00000353332	82.3846	75.8462	bos_grunniens	ENSBGRP00000025124	84.5972	77.8831
ENSG00000258366	homo_sapiens	ENSP00000353332	78.3077	71.5385	chinchilla_lanigera	ENSCLAP00000007870	86.1981	78.7468
ENSG00000258366	homo_sapiens	ENSP00000353332	83	76.1538	cervus_hanglu_yarkandensis	ENSCHYP00000033190	85.1618	78.1373
ENSG00000258366	homo_sapiens	ENSP00000353332	79.8462	71.8462	catagonus_wagneri	ENSCWAP00000014389	79.7235	71.7358
ENSG00000258366	homo_sapiens	ENSP00000353332	78.6154	71.6923	ictidomys_tridecemlineatus	ENSSTOP00000010738	81.3694	74.2038
ENSG00000258366	homo_sapiens	ENSP00000353332	84.8462	79.0769	otolemur_garnettii	ENSOGAP00000018996	86.1046	80.2498
ENSG00000258366	homo_sapiens	ENSP00000353332	89.9231	86.9231	cebus_imitator	ENSCCAP00000020640	86.9145	84.0149
ENSG00000258366	homo_sapiens	ENSP00000353332	77.8462	70.7692	urocitellus_parryii	ENSUPAP00010005630	82.7473	75.2249
ENSG00000258366	homo_sapiens	ENSP00000353332	78.8462	72.6154	moschus_moschiferus	ENSMMSP00000030527	84.9213	78.2104
ENSG00000258366	homo_sapiens	ENSP00000353332	96.0769	94.6923	rhinopithecus_roxellana	ENSRROP00000030079	96.1509	94.7652
ENSG00000258366	homo_sapiens	ENSP00000353332	77.9231	70.4615	mus_pahari	MGP_PahariEiJ_P0067729	82.9648	75.0205
ENSG00000258366	homo_sapiens	ENSP00000353332	87.1538	82.0769	propithecus_coquereli	ENSPCOP00000005128	88.1026	82.9705
ENSG00000258366	homo_sapiens	ENSP00000353332	39	25.3077	caenorhabditis_elegans	F25H2.13.2	51.006	33.0986
ENSG00000258366	homo_sapiens	ENSP00000353332	42.6923	29.0769	drosophila_melanogaster	FBpp0304672	56.3452	38.3756
ENSG00000258366	homo_sapiens	ENSP00000353332	14.9231	10.7692	ciona_intestinalis	ENSCINP00000033303	62.5806	45.1613
ENSG00000258366	homo_sapiens	ENSP00000353332	17.0769	12.3077	ciona_intestinalis	ENSCINP00000034084	63.6103	45.8453
ENSG00000258366	homo_sapiens	ENSP00000353332	20.3846	15.7692	petromyzon_marinus	ENSPMAP00000008915	72.8022	56.3187
ENSG00000258366	homo_sapiens	ENSP00000353332	29.3077	21.8462	petromyzon_marinus	ENSPMAP00000009291	61.5509	45.8805
ENSG00000258366	homo_sapiens	ENSP00000353332	41.0769	31.6923	eptatretus_burgeri	ENSEBUP00000018862	66.6667	51.4357
ENSG00000258366	homo_sapiens	ENSP00000353332	70.2308	55.8462	callorhinchus_milii	ENSCMIP00000030448	70.611	56.1485
ENSG00000258366	homo_sapiens	ENSP00000353332	67	51.6154	latimeria_chalumnae	ENSLACP00000004135	60.7816	46.8248
ENSG00000258366	homo_sapiens	ENSP00000353332	9.30769	7.07692	lepisosteus_oculatus	ENSLOCP00000000598	76.5823	58.2278
ENSG00000258366	homo_sapiens	ENSP00000353332	59.7692	46.8462	lepisosteus_oculatus	ENSLOCP00000001964	69.5613	54.521
ENSG00000258366	homo_sapiens	ENSP00000353332	53.8462	42.3077	clupea_harengus	ENSCHAP00000020814	62.3886	49.0196
ENSG00000258366	homo_sapiens	ENSP00000353332	63.7692	48.0769	danio_rerio	ENSDARP00000105420	70.4333	53.1011
ENSG00000258366	homo_sapiens	ENSP00000353332	47.3846	34.4615	carassius_auratus	ENSCARP00000092493	66.5946	48.4324
ENSG00000258366	homo_sapiens	ENSP00000353332	42.3077	31.8462	carassius_auratus	ENSCARP00000109616	66.345	49.9397
ENSG00000258366	homo_sapiens	ENSP00000353332	63.4615	48.4615	carassius_auratus	ENSCARP00000116053	70.5128	53.8462
ENSG00000258366	homo_sapiens	ENSP00000353332	63.4615	49	astyanax_mexicanus	ENSAMXP00000019123	70.2128	54.2128
ENSG00000258366	homo_sapiens	ENSP00000353332	63.0769	48.5385	ictalurus_punctatus	ENSIPUP00000018925	69.7872	53.7021
ENSG00000258366	homo_sapiens	ENSP00000353332	64.5385	50.2308	esox_lucius	ENSELUP00000002261	70.0334	54.5075
ENSG00000258366	homo_sapiens	ENSP00000353332	63.1538	48.3077	electrophorus_electricus	ENSEEEP00000009043	70.5933	53.9983
ENSG00000258366	homo_sapiens	ENSP00000353332	65.4615	50.8462	oncorhynchus_kisutch	ENSOKIP00005054286	70.447	54.7185
ENSG00000258366	homo_sapiens	ENSP00000353332	61.8462	48.0769	oncorhynchus_mykiss	ENSOMYP00000093569	69.913	54.3478
ENSG00000258366	homo_sapiens	ENSP00000353332	65.3077	50.6154	salmo_salar	ENSSSAP00000165812	69.3627	53.7582
ENSG00000258366	homo_sapiens	ENSP00000353332	65.2308	50.4615	salmo_trutta	ENSSTUP00000089344	70.2568	54.3496
ENSG00000258366	homo_sapiens	ENSP00000353332	60.3077	45.6923	gadus_morhua	ENSGMOP00000053113	68.4716	51.8777
ENSG00000258366	homo_sapiens	ENSP00000353332	53.3077	39.1538	fundulus_heteroclitus	ENSFHEP00000015806	67.2163	49.3695
ENSG00000258366	homo_sapiens	ENSP00000353332	63.8462	48.3077	poecilia_reticulata	ENSPREP00000012657	70.339	53.2203
ENSG00000258366	homo_sapiens	ENSP00000353332	63.5385	47.4615	xiphophorus_maculatus	ENSXMAP00000004639	70.9013	52.9614
ENSG00000258366	homo_sapiens	ENSP00000353332	62.1538	47	cyclopterus_lumpus	ENSCLMP00005041223	67.3895	50.9591
ENSG00000258366	homo_sapiens	ENSP00000353332	60.9231	45.5385	oreochromis_niloticus	ENSONIP00000051075	68.9895	51.5679
ENSG00000258366	homo_sapiens	ENSP00000353332	49.7692	37.6923	oreochromis_niloticus	ENSONIP00000044851	67.1859	50.8827
ENSG00000258366	homo_sapiens	ENSP00000353332	59.9231	44.0769	haplochromis_burtoni	ENSHBUP00000033078	68.5136	50.3958
ENSG00000258366	homo_sapiens	ENSP00000353332	57.6923	42.7692	astatotilapia_calliptera	ENSACLP00000004731	66.7854	49.5102
ENSG00000258366	homo_sapiens	ENSP00000353332	64.2308	48.9231	sparus_aurata	ENSSAUP00010028497	70.9431	54.0357
ENSG00000258366	homo_sapiens	ENSP00000353332	59.1538	44.6154	lates_calcarifer	ENSLCAP00010033459	69.4043	52.3466
ENSG00000258366	homo_sapiens	ENSP00000353332	66.2308	53.5385	xenopus_tropicalis	ENSXETP00000110464	71.3339	57.6636
ENSG00000258366	homo_sapiens	ENSP00000353332	70.3846	57	chrysemys_picta_bellii	ENSCPBP00000020413	73.2586	59.3275
ENSG00000258366	homo_sapiens	ENSP00000353332	63.6923	51.7692	sphenodon_punctatus	ENSSPUP00000024204	70.6485	57.4232
ENSG00000258366	homo_sapiens	ENSP00000353332	65.0769	51.3077	crocodylus_porosus	ENSCPRP00005009156	73.822	58.2024
ENSG00000258366	homo_sapiens	ENSP00000353332	50.6923	40.6923	notechis_scutatus	ENSNSUP00000026024	72.4973	58.1958
ENSG00000258366	homo_sapiens	ENSP00000353332	56.3846	43.6923	pseudonaja_textilis	ENSPTXP00000018951	69.2162	53.6355
ENSG00000258366	homo_sapiens	ENSP00000353332	45.0769	34.7692	anas_platyrhynchos_platyrhynchos	ENSAPLP00000010957	62.7409	48.394
ENSG00000258366	homo_sapiens	ENSP00000353332	71	57.3077	gallus_gallus	ENSGALP00010037725	70.6197	57.0008
ENSG00000258366	homo_sapiens	ENSP00000353332	62.4615	50.6923	meleagris_gallopavo	ENSMGAP00000032839	66.7763	54.1941
ENSG00000258366	homo_sapiens	ENSP00000353332	71.4615	58.3846	serinus_canaria	ENSSCAP00000020031	69.4839	56.7689
ENSG00000258366	homo_sapiens	ENSP00000353332	71.8462	58.4615	parus_major	ENSPMJP00000008743	71.7358	58.3717
ENSG00000258366	homo_sapiens	ENSP00000353332	71	57.2308	anolis_carolinensis	ENSACAP00000027171	71	57.2308
ENSG00000258366	homo_sapiens	ENSP00000353332	59.9231	44.0769	neolamprologus_brichardi	ENSNBRP00000006740	67.9756	50
ENSG00000258366	homo_sapiens	ENSP00000353332	54.0769	43.3077	naja_naja	ENSNNAP00000002702	74.2344	59.4509
ENSG00000258366	homo_sapiens	ENSP00000353332	71.1538	57	podarcis_muralis	ENSPMRP00000006575	71.2635	57.0878
ENSG00000258366	homo_sapiens	ENSP00000353332	70.4615	56.9231	geospiza_fortis	ENSGFOP00000001112	71.6185	57.8577
ENSG00000258366	homo_sapiens	ENSP00000353332	71.9231	58.3846	taeniopygia_guttata	ENSTGUP00000007231	71.8678	58.3397
ENSG00000258366	homo_sapiens	ENSP00000353332	65.2308	51	erpetoichthys_calabaricus	ENSECRP00000015361	72.6027	56.7637
ENSG00000258366	homo_sapiens	ENSP00000353332	63.0769	48.5385	kryptolebias_marmoratus	ENSKMAP00000003058	69.5505	53.5199
ENSG00000258366	homo_sapiens	ENSP00000353332	69.4615	54.7692	salvator_merianae	ENSSMRP00000025176	64.3621	50.7484
ENSG00000258366	homo_sapiens	ENSP00000353332	58.7692	43.6923	amphilophus_citrinellus	ENSACIP00000009837	70.8063	52.6413
ENSG00000258366	homo_sapiens	ENSP00000353332	63.3846	47.3077	dicentrarchus_labrax	ENSDLAP00005069715	70.6084	52.6992
ENSG00000258366	homo_sapiens	ENSP00000353332	56.7692	43.5385	amphiprion_percula	ENSAPEP00000008501	69.6884	53.4466
ENSG00000258366	homo_sapiens	ENSP00000353332	64.1538	48.4615	oryzias_sinensis	ENSOSIP00000033197	71.588	54.0773
ENSG00000258366	homo_sapiens	ENSP00000353332	72.7692	58.2308	pelodiscus_sinensis	ENSPSIP00000015752	72.2137	57.7863
ENSG00000258366	homo_sapiens	ENSP00000353332	71.8462	58.0769	gopherus_evgoodei	ENSGEVP00005014877	72.291	58.4365
ENSG00000258366	homo_sapiens	ENSP00000353332	66.5385	53.9231	chelonoidis_abingdonii	ENSCABP00000000673	72.628	58.8581
ENSG00000258366	homo_sapiens	ENSP00000353332	55.2308	41.6154	seriola_dumerili	ENSSDUP00000002676	69.372	52.2705
ENSG00000258366	homo_sapiens	ENSP00000353332	60.0769	44.4615	cottoperca_gobio	ENSCGOP00000014877	68.6895	50.8355
ENSG00000258366	homo_sapiens	ENSP00000353332	71.6154	58.1538	struthio_camelus_australis	ENSSCUP00000017288	68.8101	55.8758
ENSG00000258366	homo_sapiens	ENSP00000353332	70.6154	57	anser_brachyrhynchus	ENSABRP00000008029	65.2452	52.6652
ENSG00000258366	homo_sapiens	ENSP00000353332	62.7692	48.3077	gasterosteus_aculeatus	ENSGACP00000017614	69.1525	53.2203
ENSG00000258366	homo_sapiens	ENSP00000353332	60.5385	45.1538	cynoglossus_semilaevis	ENSCSEP00000007024	70.9648	52.9306
ENSG00000258366	homo_sapiens	ENSP00000353332	63.9231	48	poecilia_formosa	ENSPFOP00000017380	70.4237	52.8814
ENSG00000258366	homo_sapiens	ENSP00000353332	63.6154	48.9231	myripristis_murdjan	ENSMMDP00005001475	69.9662	53.8071
ENSG00000258366	homo_sapiens	ENSP00000353332	62.6154	47.5385	sander_lucioperca	ENSSLUP00000053712	69.3947	52.6854
ENSG00000258366	homo_sapiens	ENSP00000353332	64.3077	52.0769	strigops_habroptila	ENSSHBP00005014671	68.9769	55.8581
ENSG00000258366	homo_sapiens	ENSP00000353332	59.4615	45.7692	amphiprion_ocellaris	ENSAOCP00000028929	71.907	55.3488
ENSG00000258366	homo_sapiens	ENSP00000353332	73	58.6154	terrapene_carolina_triunguis	ENSTMTP00000000978	72.6646	58.3461
ENSG00000258366	homo_sapiens	ENSP00000353332	20.6923	17.0769	hucho_hucho	ENSHHUP00000008369	78.4257	64.723
ENSG00000258366	homo_sapiens	ENSP00000353332	21	17.4615	hucho_hucho	ENSHHUP00000008359	84	69.8462
ENSG00000258366	homo_sapiens	ENSP00000353332	64.3846	48.0769	betta_splendens	ENSBSLP00000018485	70.1005	52.3451
ENSG00000258366	homo_sapiens	ENSP00000353332	63.7692	48.9231	pygocentrus_nattereri	ENSPNAP00000006410	71.2812	54.6862
ENSG00000258366	homo_sapiens	ENSP00000353332	64.3846	47.6154	anabas_testudineus	ENSATEP00000064852	70.9924	52.5021
ENSG00000258366	homo_sapiens	ENSP00000353332	34.1538	25.0769	ciona_savignyi	ENSCSAVP00000003409	63.3381	46.505
ENSG00000258366	homo_sapiens	ENSP00000353332	61.8462	47.0769	seriola_lalandi_dorsalis	ENSSLDP00000021488	70.9621	54.0159
ENSG00000258366	homo_sapiens	ENSP00000353332	63.6923	47.7692	labrus_bergylta	ENSLBEP00000019805	70.229	52.6718
ENSG00000258366	homo_sapiens	ENSP00000353332	61.9231	46.1538	pundamilia_nyererei	ENSPNYP00000000993	70.8004	52.7704
ENSG00000258366	homo_sapiens	ENSP00000353332	64.3077	49.1538	mastacembelus_armatus	ENSMAMP00000021651	71.1489	54.383
ENSG00000258366	homo_sapiens	ENSP00000353332	64.3077	49.1538	stegastes_partitus	ENSSPAP00000003886	71.1489	54.383
ENSG00000258366	homo_sapiens	ENSP00000353332	64	49.4615	oncorhynchus_tshawytscha	ENSOTSP00005096517	68.7603	53.1405
ENSG00000258366	homo_sapiens	ENSP00000353332	41.6154	30.4615	acanthochromis_polyacanthus	ENSAPOP00000019366	66.7078	48.8286
ENSG00000258366	homo_sapiens	ENSP00000353332	65.2308	52.9231	aquila_chrysaetos_chrysaetos	ENSACCP00020001145	73.293	59.4641
ENSG00000258366	homo_sapiens	ENSP00000353332	62	46.7692	nothobranchius_furzeri	ENSNFUP00015014655	68.363	51.5691
ENSG00000258366	homo_sapiens	ENSP00000353332	63.6923	48.1538	cyprinodon_variegatus	ENSCVAP00000017597	70.7692	53.5043
ENSG00000258366	homo_sapiens	ENSP00000353332	63.7692	48.8462	denticeps_clupeoides	ENSDCDP00000032030	70.6133	54.0886
ENSG00000258366	homo_sapiens	ENSP00000353332	63.0769	47	larimichthys_crocea	ENSLCRP00005043726	68.5046	51.0443
ENSG00000258366	homo_sapiens	ENSP00000353332	59.7692	45.0769	takifugu_rubripes	ENSTRUP00000024839	68.579	51.7211
ENSG00000258366	homo_sapiens	ENSP00000353332	69.4615	56.7692	ficedula_albicollis	ENSFALP00000030336	71.327	58.2938
ENSG00000258366	homo_sapiens	ENSP00000353332	54.5385	40.8462	hippocampus_comes	ENSHCOP00000024322	68.0422	50.9597
ENSG00000258366	homo_sapiens	ENSP00000353332	47.2308	35.2308	cyprinus_carpio_carpio	ENSCCRP00000030687	64.6997	48.2613
ENSG00000258366	homo_sapiens	ENSP00000353332	63.6154	48.6154	cyprinus_carpio_carpio	ENSCCRP00000109753	66.16	50.56
ENSG00000258366	homo_sapiens	ENSP00000353332	67.3846	55	coturnix_japonica	ENSCJPP00005006666	72.4566	59.1398
ENSG00000258366	homo_sapiens	ENSP00000353332	63.9231	48	poecilia_latipinna	ENSPLAP00000015339	70.6032	53.0161
ENSG00000258366	homo_sapiens	ENSP00000353332	49.5385	35.6923	sinocyclocheilus_grahami	ENSSGRP00000065215	66.9439	48.2328
ENSG00000258366	homo_sapiens	ENSP00000353332	63.8462	48.3077	sinocyclocheilus_grahami	ENSSGRP00000069677	70.339	53.2203
ENSG00000258366	homo_sapiens	ENSP00000353332	59.7692	44.3846	maylandia_zebra	ENSMZEP00005009509	68.7003	51.0168
ENSG00000258366	homo_sapiens	ENSP00000353332	18.8462	15.1538	tetraodon_nigroviridis	ENSTNIP00000006362	80.8581	65.0165
ENSG00000258366	homo_sapiens	ENSP00000353332	64.3077	49.8462	paramormyrops_kingsleyae	ENSPKIP00000031344	69.3201	53.7313
ENSG00000258366	homo_sapiens	ENSP00000353332	65.0769	49.6154	scleropages_formosus	ENSSFOP00015000924	70.8543	54.0201
ENSG00000258366	homo_sapiens	ENSP00000353332	68.3846	54.3846	leptobrachium_leishanense	ENSLLEP00000017294	71.0631	56.5148
ENSG00000258366	homo_sapiens	ENSP00000353332	58.4615	43.7692	scophthalmus_maximus	ENSSMAP00000004858	69.7888	52.2498
ENSG00000258366	homo_sapiens	ENSP00000353332	62.3846	46.8462	oryzias_melastigma	ENSOMEP00000020937	69.0801	51.8739

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0000723	involved_in telomere maintenance	2	IMP,ISS	Homo_sapiens(9606)	Process
GO:0000732	involved_in strand displacement	2	ISS,TAS	Homo_sapiens(9606)	Process
GO:0000781	located_in chromosome, telomeric region	1	ISS	Homo_sapiens(9606)	Component
GO:0003677	enables DNA binding	1	IEA	Homo_sapiens(9606)	Function
GO:0003678	enables DNA helicase activity	4	IBA,IMP,ISS,TAS	Homo_sapiens(9606)	Function
GO:0005515	enables protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0005524	enables ATP binding	2	IBA,IMP	Homo_sapiens(9606)	Function
GO:0005634	is_active_in nucleus	3	IBA,IDA,ISS	Homo_sapiens(9606)	Component
GO:0005654	located_in nucleoplasm	2	IDA,TAS	Homo_sapiens(9606)	Component
GO:0006281	involved_in DNA repair	1	IEA	Homo_sapiens(9606)	Process
GO:0010569	involved_in regulation of double-strand break repair via homologous recombination	2	IBA,IMP	Homo_sapiens(9606)	Process
GO:0016607	located_in nuclear speck	1	IDA	Homo_sapiens(9606)	Component
GO:0016887	enables ATP hydrolysis activity	1	IEA	Homo_sapiens(9606)	Function
GO:0031297	involved_in replication fork processing	1	ISS	Homo_sapiens(9606)	Process
GO:0031965	located_in nuclear membrane	1	IDA	Homo_sapiens(9606)	Component
GO:0032206	involved_in positive regulation of telomere maintenance	1	ISS	Homo_sapiens(9606)	Process
GO:0032508	involved_in DNA duplex unwinding	2	IBA,ISS	Homo_sapiens(9606)	Process
GO:0043247	involved_in telomere maintenance in response to DNA damage	1	ISS	Homo_sapiens(9606)	Process
GO:0045910	involved_in negative regulation of DNA recombination	2	IBA,ISS	Homo_sapiens(9606)	Process
GO:0046872	enables metal ion binding	1	IEA	Homo_sapiens(9606)	Function
GO:0051539	enables 4 iron, 4 sulfur cluster binding	1	IEA	Homo_sapiens(9606)	Function
GO:0070182	enables DNA polymerase binding	1	IBA	Homo_sapiens(9606)	Function
GO:0090657	involved_in telomeric loop disassembly	3	IBA,IMP,ISS	Homo_sapiens(9606)	Process
GO:1902990	involved_in mitotic telomere maintenance via semi-conservative replication	1	ISS	Homo_sapiens(9606)	Process
GO:1904355	involved_in positive regulation of telomere capping	1	IMP	Homo_sapiens(9606)	Process
GO:1904358	involved_in positive regulation of telomere maintenance via telomere lengthening	1	IMP	Homo_sapiens(9606)	Process
GO:1904430	involved_in negative regulation of t-circle formation	4	IBA,IMP,ISS,TAS	Homo_sapiens(9606)	Process
GO:1904506	involved_in negative regulation of telomere maintenance in response to DNA damage	1	ISS	Homo_sapiens(9606)	Process
GO:1904535	involved_in positive regulation of telomeric loop disassembly	1	ISS	Homo_sapiens(9606)	Process