Functions and Diseases

RBP Type Canonical_RBPs
Diseases Cancer
Drug N.A.
Main interacting RNAs mRNA
Moonlighting functions N.A.
Localizations N.A.
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000254535 Gene ID 132430 Accession 31955
Symbol PABPC4L Alias NA Full Name poly(A) binding protein cytoplasmic 4 like
Status Confidence Length 5457 bases Strand Minus strand
Position 4 : 134196333 - 134201789 RNA binding domain RRM_5 , RRM_1
Summary Predicted to enable mRNA 3'-UTR binding activity; poly(A) binding activity; and poly(U) RNA binding activity. Predicted to be part of ribonucleoprotein complex. Predicted to be active in cytoplasmic stress granule; cytosol; and nucleus. [provided by Alliance of Genome Resources, Apr 2022]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000463233 RRM_1 PF00076 6e-84 1
ENSP00000463233 RRM_1 PF00076 6e-84 2
ENSP00000463233 RRM_1 PF00076 6e-84 3
ENSP00000463233 RRM_1 PF00076 6e-84 4
ENSP00000463233 RRM_5 PF13893 2.3e-13 5
ENSP00000463233 RRM_5 PF13893 2.3e-13 6

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
37577627 KAT6A mutations in Arboleda-Tham syndrome drive epigenetic regulation of posterior HOXC cluster. Meghna Singh 2023-08-05 bioRxiv : the preprint server for biology

Transcripts

Name Transcript ID bp Protein Translation ID
PABPC4L-201 ENST00000421491 4985 370aa ENSP00000463233

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
5650Apolipoproteins B8.28509725157023E-517903299
18842Platelet Count8.901e-005-
18863Platelet Count8.901e-005-

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000254535homo_sapiensENSP0000028607022.995811.8143homo_sapiensENSP0000046323329.459515.1351
ENSG00000254535homo_sapiensENSP0000029490430.788216.7488homo_sapiensENSP0000046323333.783818.3784
ENSG00000254535homo_sapiensENSP0000031300749.528341.8239homo_sapiensENSP0000046323385.135171.8919
ENSG00000254535homo_sapiensENSP0000028158947.702139.6197homo_sapiensENSP0000046323381.351367.5676
ENSG00000254535homo_sapiensENSP0000035216230.517715.5313homo_sapiensENSP0000046323330.270315.4054
ENSG00000254535homo_sapiensENSP0000030440524.328614.06homo_sapiensENSP0000046323341.621624.0541
ENSG00000254535homo_sapiensENSP0000035863525.200614.6067homo_sapiensENSP0000046323342.432424.5946
ENSG00000254535homo_sapiensENSP0000030801276.17858.9005homo_sapiensENSP0000046323378.648760.8108
ENSG00000254535homo_sapiensENSP0000038526929.447916.2577homo_sapiensENSP0000046323325.945914.3243
ENSG00000254535homo_sapiensENSP0000026203130.712516.9533homo_sapiensENSP0000046323333.783818.6486
ENSG00000254535homo_sapiensENSP0000038622627.674413.2558homo_sapiensENSP0000046323332.162215.4054
ENSG00000254535homo_sapiensENSP0000027162825.235814.3868homo_sapiensENSP0000046323328.918916.4865
ENSG00000254535homo_sapiensENSP0000031174713.30346.57698homo_sapiensENSP0000046323324.054111.8919
ENSG00000254535homo_sapiensENSP0000034853825.941413.8075homo_sapiensENSP0000046323316.75688.91892
ENSG00000254535homo_sapiensENSP0000036088930.874315.5738homo_sapiensENSP0000046323330.540515.4054
ENSG00000254535homo_sapiensENSP0000036834127.966113.9831homo_sapiensENSP0000046323317.83788.91892
ENSG00000254535homo_sapiensENSP0000038047931.476316.4345homo_sapiensENSP0000046323330.540515.9459
ENSG00000254535homo_sapiensENSP0000036194949.090942.4242homo_sapiensENSP0000046323387.567675.6757
ENSG00000254535homo_sapiensENSP0000043435920.572510.1968homo_sapiensENSP0000046323331.081115.4054
ENSG00000254535homo_sapiensENSP0000037327729.061814.4165homo_sapiensENSP0000046323334.324317.027
ENSG00000254535homo_sapiensENSP0000024018524.879212.8019homo_sapiensENSP0000046323327.837814.3243
ENSG00000254535homo_sapiensENSP0000021707348.788437.9645homo_sapiensENSP0000046323381.621663.5135
ENSG00000254535homo_sapiensENSP000003626217862homo_sapiensENSP0000046323342.162233.5135
ENSG00000254535homo_sapiensENSP000003626187862homo_sapiensENSP0000046323342.162233.5135

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000254535homo_sapiensENSP0000046323310099.4595nomascus_leucogenysENSNLEP0000003411110099.4595
ENSG00000254535homo_sapiensENSP0000046323389.459587.8378pan_paniscusENSPPAP0000004234094.034192.3295
ENSG00000254535homo_sapiensENSP0000046323399.729799.4595pongo_abeliiENSPPYP0000003225699.729799.4595
ENSG00000254535homo_sapiensENSP0000046323391.621688.6487pan_troglodytesENSPTRP0000006884478.837276.2791
ENSG00000254535homo_sapiensENSP0000046323310099.4595gorilla_gorillaENSGGOP0000003407710099.4595
ENSG00000254535homo_sapiensENSP0000046323396.216292.1622dasypus_novemcinctusENSDNOP0000002074291.752687.8866
ENSG00000254535homo_sapiensENSP0000046323396.486594.8649macaca_fascicularisENSMFAP0000006275196.486594.8649
ENSG00000254535homo_sapiensENSP0000046323396.486594.8649macaca_mulattaENSMMUP0000006200896.486594.8649
ENSG00000254535homo_sapiensENSP0000046323396.486594.8649papio_anubisENSPANP0000005061896.486594.8649
ENSG00000254535homo_sapiensENSP0000046323346.216236.7568vulpes_vulpesENSVVUP0000001508778.082262.1005
ENSG00000254535homo_sapiensENSP000004632339080.8108mus_spretusMGP_SPRETEiJ_P00598169080.8108
ENSG00000254535homo_sapiensENSP0000046323395.675789.4595equus_asinusENSEASP0000501119695.675789.4595
ENSG00000254535homo_sapiensENSP0000046323395.135189.4595capra_hircusENSCHIP0000000324095.135189.4595
ENSG00000254535homo_sapiensENSP0000046323395.675790panthera_leoENSPLOP0000001176895.675790
ENSG00000254535homo_sapiensENSP0000046323394.864988.9189ailuropoda_melanoleucaENSAMEP0000004305894.864988.9189
ENSG00000254535homo_sapiensENSP0000046323395.135189.4595bos_indicus_hybridENSBIXP0000503002295.135189.4595
ENSG00000254535homo_sapiensENSP0000046323395.405488.6487oryctolagus_cuniculusENSOCUP0000002845595.405488.6487
ENSG00000254535homo_sapiensENSP0000046323396.216289.7297equus_caballusENSECAP0000002526396.216289.7297
ENSG00000254535homo_sapiensENSP0000046323390.540573.7838canis_lupus_familiarisENSCAFP0084503223690.540573.7838
ENSG00000254535homo_sapiensENSP0000046323395.405489.4595panthera_pardusENSPPRP0000002728595.405489.4595
ENSG00000254535homo_sapiensENSP0000046323394.054189.1892marmota_marmota_marmotaENSMMMP0000001660393.800588.9488
ENSG00000254535homo_sapiensENSP0000046323395.945990balaenoptera_musculusENSBMSP0001000903495.945990
ENSG00000254535homo_sapiensENSP0000046323389.189278.3784cavia_porcellusENSCPOP0000002942791.92280.7799
ENSG00000254535homo_sapiensENSP0000046323395.675790felis_catusENSFCAP0000003278595.675790
ENSG00000254535homo_sapiensENSP0000046323394.864989.1892ursus_americanusENSUAMP0000000134594.864989.1892
ENSG00000254535homo_sapiensENSP0000046323393.243287.027bison_bison_bisonENSBBBP0000001893394.780288.4615
ENSG00000254535homo_sapiensENSP0000046323395.135189.4595monodon_monocerosENSMMNP0001501841095.135189.4595
ENSG00000254535homo_sapiensENSP0000046323388.918984.0541sus_scrofaENSSSCP0000005711896.480991.2023
ENSG00000254535homo_sapiensENSP0000046323397.567695.1351microcebus_murinusENSMICP0000004646297.567695.1351
ENSG00000254535homo_sapiensENSP0000046323391.891982.7027jaculus_jaculusENSJJAP0000000239691.891982.7027
ENSG00000254535homo_sapiensENSP0000046323395.135189.1892ovis_aries_rambouilletENSOARP0002002080295.135189.1892
ENSG00000254535homo_sapiensENSP0000046323394.864989.1892ursus_maritimusENSUMAP0000002034594.864989.1892
ENSG00000254535homo_sapiensENSP0000046323358.648654.5946delphinapterus_leucasENSDLEP0000001907092.340485.9574
ENSG00000254535homo_sapiensENSP0000046323395.405489.7297delphinapterus_leucasENSDLEP0000002615295.405489.7297
ENSG00000254535homo_sapiensENSP0000046323388.918982.7027physeter_catodonENSPCTP0000500598191.135784.7645
ENSG00000254535homo_sapiensENSP0000046323395.675790physeter_catodonENSPCTP0000501868195.675790
ENSG00000254535homo_sapiensENSP0000046323389.459581.0811mus_caroliMGP_CAROLIEiJ_P005755189.459581.0811
ENSG00000254535homo_sapiensENSP0000046323390.270381.3513mus_musculusENSMUSP0000014130090.270381.3513
ENSG00000254535homo_sapiensENSP0000046323398.378497.027aotus_nancymaaeENSANAP0000000214185.245984.0749
ENSG00000254535homo_sapiensENSP0000046323397.567695.1351saimiri_boliviensis_boliviensisENSSBOP0000000334497.567695.1351
ENSG00000254535homo_sapiensENSP0000046323391.081183.2432mesocricetus_auratusENSMAUP0000001743891.081183.2432
ENSG00000254535homo_sapiensENSP0000046323395.405489.7297phocoena_sinusENSPSNP0000000376395.405489.7297
ENSG00000254535homo_sapiensENSP0000046323396.486590.8108camelus_dromedariusENSCDRP0000500228296.486590.8108
ENSG00000254535homo_sapiensENSP0000046323395.675790panthera_tigris_altaicaENSPTIP0000000885895.675790
ENSG00000254535homo_sapiensENSP0000046323389.459581.8919rattus_norvegicusENSRNOP0000001701289.459581.8919
ENSG00000254535homo_sapiensENSP0000046323397.837895.4054prolemur_simusENSPSMP0000001824597.837895.4054
ENSG00000254535homo_sapiensENSP0000046323391.621684.3243microtus_ochrogasterENSMOCP0000000769991.621684.3243
ENSG00000254535homo_sapiensENSP0000046323391.081183.2432peromyscus_maniculatus_bairdiiENSPEMP0000001213491.081183.2432
ENSG00000254535homo_sapiensENSP0000046323394.864989.1892bos_mutusENSBMUP0000002282794.864989.1892
ENSG00000254535homo_sapiensENSP0000046323390.270381.3513mus_spicilegusENSMSIP0000000871490.270381.3513
ENSG00000254535homo_sapiensENSP0000046323390.810882.973cricetulus_griseus_chok1gshdENSCGRP0000100203890.810882.973
ENSG00000254535homo_sapiensENSP000004632339078.6487myotis_lucifugusENSMLUP000000224659078.6487
ENSG00000254535homo_sapiensENSP0000046323395.135188.1081rhinolophus_ferrumequinumENSRFEP0001001694595.135188.1081
ENSG00000254535homo_sapiensENSP0000046323394.324388.6487neovison_visonENSNVIP0000001881994.324388.6487
ENSG00000254535homo_sapiensENSP0000046323395.135189.4595bos_taurusENSBTAP0000006053995.135189.4595
ENSG00000254535homo_sapiensENSP0000046323392.702783.7838heterocephalus_glaber_femaleENSHGLP0000005958592.702783.7838
ENSG00000254535homo_sapiensENSP0000046323398.918995.9459rhinopithecus_bietiENSRBIP0000001252598.918995.9459
ENSG00000254535homo_sapiensENSP0000046323390.270373.5135canis_lupus_dingoENSCAFP0002002436948.68839.6501
ENSG00000254535homo_sapiensENSP0000046323394.594689.7297sciurus_vulgarisENSSVLP0000500835094.339689.4879
ENSG00000254535homo_sapiensENSP0000046323393.243287.5676nannospalax_galiliENSNGAP0000000199393.243287.5676
ENSG00000254535homo_sapiensENSP0000046323395.135189.4595bos_grunniensENSBGRP0000000732795.135189.4595
ENSG00000254535homo_sapiensENSP0000046323392.97383.7838chinchilla_lanigeraENSCLAP0000002554092.97383.7838
ENSG00000254535homo_sapiensENSP0000046323395.135189.4595cervus_hanglu_yarkandensisENSCHYP0000000578295.135189.4595
ENSG00000254535homo_sapiensENSP0000046323395.945991.8919catagonus_wagneriENSCWAP0000002798295.945991.8919
ENSG00000254535homo_sapiensENSP0000046323394.054187.8378ictidomys_tridecemlineatusENSSTOP0000002071593.548487.3656
ENSG00000254535homo_sapiensENSP0000046323391.081187.5676otolemur_garnettiiENSOGAP0000001655396.011492.3077
ENSG00000254535homo_sapiensENSP0000046323398.108197.2973cebus_imitatorENSCCAP0000002763084.813184.1122
ENSG00000254535homo_sapiensENSP0000046323393.513587.8378urocitellus_parryiiENSUPAP0001001563193.261587.6011
ENSG00000254535homo_sapiensENSP0000046323395.135188.9189moschus_moschiferusENSMMSP0000000153295.135188.9189
ENSG00000254535homo_sapiensENSP0000046323398.648795.6757rhinopithecus_roxellanaENSRROP0000000490798.648795.6757
ENSG00000254535homo_sapiensENSP000004632339081.6216mus_pahariMGP_PahariEiJ_P00685129081.6216
ENSG00000254535homo_sapiensENSP0000046323397.837895.1351propithecus_coquereliENSPCOP0000002641497.837895.1351

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0003730enables mRNA 3-UTR binding1IBAHomo_sapiens(9606)Function
GO:0005634is_active_in nucleus1IBAHomo_sapiens(9606)Component
GO:0005829is_active_in cytosol1IBAHomo_sapiens(9606)Component
GO:0008143enables poly(A) binding1IBAHomo_sapiens(9606)Function
GO:0008266enables poly(U) RNA binding1IBAHomo_sapiens(9606)Function
GO:0010494is_active_in cytoplasmic stress granule1IBAHomo_sapiens(9606)Component
GO:1990904part_of ribonucleoprotein complex1IBAHomo_sapiens(9606)Component

Expression