Functions and Diseases

RBP Type Non-canonical_RBPs
Diseases CancerCHIKVFlavivirusesHIVIAVRVSARS-COV-2SINVDengueZika
Drug Drug
Main interacting RNAs mRNA
Moonlighting functions Kinase
Localizations Stress granucle
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000253729 Gene ID 5591 Accession 9413
Symbol PRKDC Alias HYRC;p350;DNAPK;DNPK1;HYRC1;IMD26;XRCC7;DNAPKc;DNA-PKC;DNA-PKcs Full Name protein kinase, DNA-activated, catalytic subunit
Status Confidence Length 187068 bases Strand Minus strand
Position 8 : 47773111 - 47960178 RNA binding domain N.A.
Summary This gene encodes the catalytic subunit of the DNA-dependent protein kinase (DNA-PK). It functions with the Ku70/Ku80 heterodimer protein in DNA double strand break repair and recombination. The protein encoded is a member of the PI3/PI4-kinase family.[provided by RefSeq, Jul 2010]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
37035744 Dynamic of centromere associated RNAs and the centromere loading of DNA repair proteins in growing oocytes. Lin-Li Yang 2023-01-01 Frontiers in genetics
35468873 PRKDC promotes hepatitis B virus transcription through enhancing the binding of RNA Pol II to cccDNA. Yao Fan 2022-04-25 Cell death & disease
33364834 Circ-PRKDC Facilitates the Progression of Colorectal Cancer Through miR-198/DDR1 Regulatory Axis. Guixiang Wang 2020-01-01 Cancer management and research

Transcripts

Name Transcript ID bp Protein Translation ID
PRKDC-201 ENST00000314191 13459 4128aa ENSP00000313420
PRKDC-213 ENST00000697601 2695 No protein -
PRKDC-214 ENST00000697602 3997 No protein -
PRKDC-215 ENST00000697603 6282 1687aa ENSP00000513358
PRKDC-216 ENST00000697604 3424 No protein -
PRKDC-202 ENST00000338368 12784 4097aa ENSP00000345182
PRKDC-206 ENST00000536429 659 90aa ENSP00000442177
PRKDC-207 ENST00000536483 834 No protein -
PRKDC-217 ENST00000697605 3114 No protein -
PRKDC-204 ENST00000521331 1087 No protein -
PRKDC-208 ENST00000536710 554 No protein -
PRKDC-218 ENST00000697606 3044 No protein -
PRKDC-203 ENST00000432581 583 No protein -
PRKDC-219 ENST00000697607 3573 No protein -
PRKDC-220 ENST00000697608 2109 No protein -
PRKDC-221 ENST00000697609 1408 No protein -
PRKDC-222 ENST00000697610 1171 No protein -
PRKDC-211 ENST00000546304 589 No protein -
PRKDC-223 ENST00000697611 1506 No protein -
PRKDC-210 ENST00000541488 719 No protein -
PRKDC-212 ENST00000697591 3522 No protein -
PRKDC-205 ENST00000535375 464 No protein -
PRKDC-209 ENST00000540819 537 70aa ENSP00000441157

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
22551Respiratory Function Tests6.6510000E-005-
25082Body Weight9.8820000E-005-

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000253729homo_sapiensENSP0000040251522.534810.7348homo_sapiensENSP0000031342019.98559.52035
ENSG00000253729homo_sapiensENSP0000035455830.56115.3393homo_sapiensENSP0000031342018.87119.4719
ENSG00000253729homo_sapiensENSP0000034374140.355520.3101homo_sapiensENSP0000031342025.847913.0087
ENSG00000253729homo_sapiensENSP0000050160633.246115.9359homo_sapiensENSP0000031342024.612411.7975
ENSG00000253729homo_sapiensENSP0000039464530.131713.5812homo_sapiensENSP0000031342028.270312.7422

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000253729homo_sapiensENSP0000031342091.424490.4312nomascus_leucogenysENSNLEP0000001611997.949696.8855
ENSG00000253729homo_sapiensENSP0000031342099.878999.6609pan_paniscusENSPPAP0000001379999.878999.6609
ENSG00000253729homo_sapiensENSP0000031342099.467199.0068pongo_abeliiENSPPYP0000002082999.491299.0308
ENSG00000253729homo_sapiensENSP0000031342099.878999.5882pan_troglodytesENSPTRP0000004526899.878999.5882
ENSG00000253729homo_sapiensENSP0000031342084.641584.4234gorilla_gorillaENSGGOP0000000594599.743199.4862
ENSG00000253729homo_sapiensENSP0000031342086.143474.8304ornithorhynchus_anatinusENSOANP0000001156485.997674.7038
ENSG00000253729homo_sapiensENSP0000031342088.178376.6231sarcophilus_harrisiiENSSHAP0000001649187.922776.401
ENSG00000253729homo_sapiensENSP0000031342063.46954.6027notamacropus_eugeniiENSMEUP0000001479363.499854.6292
ENSG00000253729homo_sapiensENSP0000031342079.772372.1899choloepus_hoffmanniENSCHOP0000000518883.536375.5961
ENSG00000253729homo_sapiensENSP0000031342090.18981.9283dasypus_novemcinctusENSDNOP0000001105190.210881.9481
ENSG00000253729homo_sapiensENSP0000031342070.445763.4932erinaceus_europaeusENSEEUP0000000705370.479963.524
ENSG00000253729homo_sapiensENSP0000031342071.220963.8081echinops_telfairiENSETEP0000000145272.306964.7811
ENSG00000253729homo_sapiensENSP0000031342097.189994.5979callithrix_jacchusENSCJAP0000007263997.048994.4606
ENSG00000253729homo_sapiensENSP0000031342099.152197.844cercocebus_atysENSCATP0000002312499.152197.844
ENSG00000253729homo_sapiensENSP0000031342099.24998.062macaca_mulattaENSMMUP0000002013299.24998.062
ENSG00000253729homo_sapiensENSP0000031342096.947795.6638macaca_nemestrinaENSMNEP0000003544798.717397.41
ENSG00000253729homo_sapiensENSP0000031342099.224897.9893papio_anubisENSPANP0000001536799.224897.9893
ENSG00000253729homo_sapiensENSP0000031342085.392484.4234mandrillus_leucophaeusENSMLEP0000001929299.128298.0034
ENSG00000253729homo_sapiensENSP0000031342080.208371.5601tursiops_truncatusENSTTRP0000000787280.364171.699
ENSG00000253729homo_sapiensENSP0000031342090.988482.7762vulpes_vulpesENSVVUP0000002247990.812482.6161
ENSG00000253729homo_sapiensENSP0000031342088.590178.7791mus_spretusMGP_SPRETEiJ_P004235488.590178.7791
ENSG00000253729homo_sapiensENSP0000031342092.078584.593equus_asinusENSEASP0000501632191.944884.4702
ENSG00000253729homo_sapiensENSP0000031342087.839177.7859capra_hircusENSCHIP0000001221588.073877.9937
ENSG00000253729homo_sapiensENSP000003134202.93122.44671loxodonta_africanaENSLAFP0000002382186.428672.1429
ENSG00000253729homo_sapiensENSP000003134204.917644.45736loxodonta_africanaENSLAFP0000000964291.855283.2579
ENSG00000253729homo_sapiensENSP0000031342091.739384.157panthera_leoENSPLOP0000000370791.650584.0755
ENSG00000253729homo_sapiensENSP0000031342091.860584.0601ailuropoda_melanoleucaENSAMEP0000000028691.70583.9178
ENSG00000253729homo_sapiensENSP0000031342087.693877.5194bos_indicus_hybridENSBIXP0000504249687.821477.6322
ENSG00000253729homo_sapiensENSP0000031342092.126984.6415equus_caballusENSECAP0000001890291.330583.9097
ENSG00000253729homo_sapiensENSP0000031342091.521383.4545canis_lupus_familiarisENSCAFP0084503847691.388583.3333
ENSG00000253729homo_sapiensENSP0000031342091.787884.1085panthera_pardusENSPPRP0000002243191.765684.0882
ENSG00000253729homo_sapiensENSP0000031342091.642484.3266marmota_marmota_marmotaENSMMMP0000002525091.553784.2449
ENSG00000253729homo_sapiensENSP0000031342087.887677.8101balaenoptera_musculusENSBMSP0001003074687.717677.6596
ENSG00000253729homo_sapiensENSP0000031342088.711280.499cavia_porcellusENSCPOP0000001256590.576382.1914
ENSG00000253729homo_sapiensENSP0000031342091.206483.4787felis_catusENSFCAP0000003680691.650483.8851
ENSG00000253729homo_sapiensENSP0000031342074.006867.4903ursus_americanusENSUAMP0000001076591.439783.3882
ENSG00000253729homo_sapiensENSP0000031342083.914772.4806monodelphis_domesticaENSMODP0000005738886.38474.6135
ENSG00000253729homo_sapiensENSP0000031342087.28277.0833bison_bison_bisonENSBBBP0000002399887.557777.3269
ENSG00000253729homo_sapiensENSP0000031342087.863478.1734monodon_monocerosENSMMNP0001502693187.884778.1924
ENSG00000253729homo_sapiensENSP0000031342088.008778.4399sus_scrofaENSSSCP0000000668787.838578.2882
ENSG00000253729homo_sapiensENSP0000031342091.327584.4719microcebus_murinusENSMICP0000001423792.13185.2151
ENSG00000253729homo_sapiensENSP0000031342089.462280.4506octodon_degusENSODEP0000000657790.007380.9408
ENSG00000253729homo_sapiensENSP0000031342089.026280.1357jaculus_jaculusENSJJAP0000000094689.047780.1551
ENSG00000253729homo_sapiensENSP0000031342086.894476.9864ovis_aries_rambouilletENSOARP0002003104287.916777.8922
ENSG00000253729homo_sapiensENSP0000031342091.957484.2054ursus_maritimusENSUMAP0000001256891.801784.0629
ENSG00000253729homo_sapiensENSP0000031342075.557266.8605ochotona_princepsENSOPRP0000000987975.648866.9416
ENSG00000253729homo_sapiensENSP0000031342087.984578.2946delphinapterus_leucasENSDLEP0000002828788.005878.3135
ENSG00000253729homo_sapiensENSP0000031342087.621177.9797physeter_catodonENSPCTP0000502366187.219777.6224
ENSG00000253729homo_sapiensENSP0000031342088.711279.094mus_caroliMGP_CAROLIEiJ_P004050188.711279.094
ENSG00000253729homo_sapiensENSP0000031342088.638679.0213mus_musculusENSMUSP0000002335288.638679.0213
ENSG00000253729homo_sapiensENSP0000031342088.832479.7723dipodomys_ordiiENSDORP0000000413289.701680.5528
ENSG00000253729homo_sapiensENSP0000031342090.576682.5339mustela_putorius_furoENSMPUP0000000101290.973282.8954
ENSG00000253729homo_sapiensENSP0000031342095.082492.0543aotus_nancymaaeENSANAP0000002178396.295493.2287
ENSG00000253729homo_sapiensENSP0000031342095.324692.6599saimiri_boliviensis_boliviensisENSSBOP0000003329997.280694.5612
ENSG00000253729homo_sapiensENSP0000031342099.127997.844chlorocebus_sabaeusENSCSAP0000001095799.055997.7729
ENSG00000253729homo_sapiensENSP0000031342067.684161.5795tupaia_belangeriENSTBEP0000000254567.766261.6541
ENSG00000253729homo_sapiensENSP0000031342077.979768.9196mesocricetus_auratusENSMAUP0000001332586.138676.1306
ENSG00000253729homo_sapiensENSP0000031342085.998176.3566phocoena_sinusENSPSNP0000002325386.988577.236
ENSG00000253729homo_sapiensENSP0000031342086.361475.3391camelus_dromedariusENSCDRP0000502776986.25775.248
ENSG00000253729homo_sapiensENSP0000031342067.78161.6037carlito_syrichtaENSTSYP0000003141191.051182.753
ENSG00000253729homo_sapiensENSP0000031342091.497183.8421panthera_tigris_altaicaENSPTIP0000000578491.585883.9234
ENSG00000253729homo_sapiensENSP0000031342088.129878.3915rattus_norvegicusENSRNOP0000003741288.172678.4295
ENSG00000253729homo_sapiensENSP0000031342092.369285.4409prolemur_simusENSPSMP0000003635392.14685.2344
ENSG00000253729homo_sapiensENSP0000031342086.53177.6163microtus_ochrogasterENSMOCP0000001583287.872178.8192
ENSG00000253729homo_sapiensENSP0000031342070.397361.4099sorex_araneusENSSARP0000000907870.947361.8896
ENSG00000253729homo_sapiensENSP0000031342088.68779.8934peromyscus_maniculatus_bairdiiENSPEMP0000000424588.579779.7968
ENSG00000253729homo_sapiensENSP0000031342081.637672.3837bos_mutusENSBMUP0000001476687.509777.5902
ENSG00000253729homo_sapiensENSP0000031342088.662878.9244mus_spicilegusENSMSIP0000001939588.662878.9244
ENSG00000253729homo_sapiensENSP0000031342088.735579.53cricetulus_griseus_chok1gshdENSCGRP0000100322388.585379.3954
ENSG00000253729homo_sapiensENSP0000031342079.287872.5048pteropus_vampyrusENSPVAP0000001435181.559974.5826
ENSG00000253729homo_sapiensENSP0000031342090.479782.2674myotis_lucifugusENSMLUP0000000068890.348382.148
ENSG00000253729homo_sapiensENSP0000031342085.465174.4671vombatus_ursinusENSVURP0001000302388.354676.9847
ENSG00000253729homo_sapiensENSP0000031342085.465174.4671vombatus_ursinusENSVURP0001000621888.354676.9847
ENSG00000253729homo_sapiensENSP0000031342091.569883.4787rhinolophus_ferrumequinumENSRFEP0001001927891.525483.4383
ENSG00000253729homo_sapiensENSP0000031342088.832481.1047neovison_visonENSNVIP0000002973391.218983.2836
ENSG00000253729homo_sapiensENSP0000031342087.742277.5678bos_taurusENSBTAP0000002263187.827477.6431
ENSG00000253729homo_sapiensENSP0000031342091.666783.3333heterocephalus_glaber_femaleENSHGLP0000001856691.312783.0116
ENSG00000253729homo_sapiensENSP0000031342099.176498.0136rhinopithecus_bietiENSRBIP0000001364599.176498.0136
ENSG00000253729homo_sapiensENSP0000031342091.182283.1638canis_lupus_dingoENSCAFP0002001929591.270683.2444
ENSG00000253729homo_sapiensENSP0000031342087.185175.436phascolarctos_cinereusENSPCIP0000003089987.930676.0811
ENSG00000253729homo_sapiensENSP0000031342065.770358.2364procavia_capensisENSPCAP0000000091465.882158.3354
ENSG00000253729homo_sapiensENSP0000031342091.157983.0184chinchilla_lanigeraENSCLAP0000001369091.047782.918
ENSG00000253729homo_sapiensENSP0000031342087.306277.156cervus_hanglu_yarkandensisENSCHYP0000002706986.07676.0688
ENSG00000253729homo_sapiensENSP0000031342091.666784.157ictidomys_tridecemlineatusENSSTOP0000000886191.622384.1162
ENSG00000253729homo_sapiensENSP0000031342089.922582.7519otolemur_garnettiiENSOGAP0000000032790.958183.705
ENSG00000253729homo_sapiensENSP0000031342097.335394.719cebus_imitatorENSCCAP0000002186697.288194.6731
ENSG00000253729homo_sapiensENSP0000031342091.303383.9874urocitellus_parryiiENSUPAP0001000405691.569584.2323
ENSG00000253729homo_sapiensENSP0000031342087.572777.2287moschus_moschiferusENSMMSP0000000272687.657677.3036
ENSG00000253729homo_sapiensENSP0000031342099.200698.0378rhinopithecus_roxellanaENSRROP0000004455698.461297.307
ENSG00000253729homo_sapiensENSP0000031342087.766578.1734mus_pahariMGP_PahariEiJ_P002789588.733879.035
ENSG00000253729homo_sapiensENSP0000031342093.192886.7248propithecus_coquereliENSPCOP0000000609693.147786.6828
ENSG00000253729homo_sapiensENSP000003134209.447676.29845ciona_intestinalisENSCINP0000002363853.71935.8127
ENSG00000253729homo_sapiensENSP0000031342010.65896.75872eptatretus_burgeriENSEBUP0000000022457.068736.1868
ENSG00000253729homo_sapiensENSP0000031342014.14739.4719eptatretus_burgeriENSEBUP0000000393163.340642.4078
ENSG00000253729homo_sapiensENSP000003134209.689926.46802eptatretus_burgeriENSEBUP0000002414757.803538.5838
ENSG00000253729homo_sapiensENSP000003134207.630814.36047eptatretus_burgeriENSEBUP0000000247353.389830.5085
ENSG00000253729homo_sapiensENSP000003134203.730622.30136eptatretus_burgeriENSEBUP0000002378262.348238.4615
ENSG00000253729homo_sapiensENSP0000031342075.242259.5446callorhinchus_miliiENSCMIP0000001263978.197461.8832
ENSG00000253729homo_sapiensENSP0000031342075.460360.6105latimeria_chalumnaeENSLACP0000001599376.291961.2785
ENSG00000253729homo_sapiensENSP0000031342076.598860.0775lepisosteus_oculatusENSLOCP0000000734176.009659.6154
ENSG00000253729homo_sapiensENSP0000031342074.079557.4855clupea_harengusENSCHAP0000005525975.135158.3047
ENSG00000253729homo_sapiensENSP0000031342074.079557.001danio_rerioENSDARP0000005167874.241357.1255
ENSG00000253729homo_sapiensENSP0000031342074.152157.0494carassius_auratusENSCARP0000000663174.332257.188
ENSG00000253729homo_sapiensENSP0000031342073.183156.2985astyanax_mexicanusENSAMXP0000000736174.007856.9329
ENSG00000253729homo_sapiensENSP0000031342074.055256.3953ictalurus_punctatusENSIPUP0000000841574.542856.7666
ENSG00000253729homo_sapiensENSP0000031342073.934156.8556esox_luciusENSELUP0000003692574.657557.4119
ENSG00000253729homo_sapiensENSP0000031342072.650255.5475electrophorus_electricusENSEEEP0000005265973.164255.9405
ENSG00000253729homo_sapiensENSP0000031342071.220954.8934oncorhynchus_kisutchENSOKIP0000506580274.581457.4835
ENSG00000253729homo_sapiensENSP0000031342074.345957.4855oncorhynchus_mykissENSOMYP0000006667574.908557.9204
ENSG00000253729homo_sapiensENSP0000031342074.78257.9215salmo_salarENSSSAP0000012418774.78257.9215
ENSG00000253729homo_sapiensENSP0000031342071.43954.3362gadus_morhuaENSGMOP0000001953473.139955.63
ENSG00000253729homo_sapiensENSP0000031342070.784954.9903fundulus_heteroclitusENSFHEP0000001893774.597957.9525
ENSG00000253729homo_sapiensENSP0000031342069.282953.5853poecilia_reticulataENSPREP0000001386473.201956.6163
ENSG00000253729homo_sapiensENSP0000031342072.286855.7171xiphophorus_maculatusENSXMAP0000000194773.280956.4833
ENSG00000253729homo_sapiensENSP0000031342070.712253.9244oryzias_latipesENSORLP0000000686773.674956.1837
ENSG00000253729homo_sapiensENSP0000031342070.227754.6027cyclopterus_lumpusENSCLMP0000503145572.674956.5054
ENSG00000253729homo_sapiensENSP0000031342068.217152.9312haplochromis_burtoniENSHBUP0000001685272.409456.1841
ENSG00000253729homo_sapiensENSP0000031342072.09355.7897astatotilapia_callipteraENSACLP0000002309273.427156.8221
ENSG00000253729homo_sapiensENSP0000031342072.819856.3469sparus_aurataENSSAUP0001001084973.984757.2483
ENSG00000253729homo_sapiensENSP0000031342077.277161.7006xenopus_tropicalisENSXETP0000001053677.766962.0917
ENSG00000253729homo_sapiensENSP0000031342083.212270.0581chrysemys_picta_belliiENSCPBP0000002970083.882870.6227
ENSG00000253729homo_sapiensENSP0000031342082.364369.2103sphenodon_punctatusENSSPUP0000000730884.703571.1759
ENSG00000253729homo_sapiensENSP0000031342080.377967.1512crocodylus_porosusENSCPRP0000502311682.210168.6819
ENSG00000253729homo_sapiensENSP0000031342076.477761.7006notechis_scutatusENSNSUP0000002834981.282265.5767
ENSG00000253729homo_sapiensENSP0000031342079.917664.6318pseudonaja_textilisENSPTXP0000000306381.236165.6981
ENSG00000253729homo_sapiensENSP0000031342082.00168.0959anas_platyrhynchos_platyrhynchosENSAPLP0000000220781.842467.9642
ENSG00000253729homo_sapiensENSP0000031342082.267468.6289gallus_gallusENSGALP0001000747279.142466.0219
ENSG00000253729homo_sapiensENSP0000031342055.668645.7364meleagris_gallopavoENSMGAP0000001121379.902665.6467
ENSG00000253729homo_sapiensENSP0000031342082.461267.563serinus_canariaENSSCAP0000001709482.301767.4323
ENSG00000253729homo_sapiensENSP0000031342081.710366.9574parus_majorENSPMJP0000002109781.277166.6024
ENSG00000253729homo_sapiensENSP0000031342079.384765.1405anolis_carolinensisENSACAP0000001189081.55866.9238
ENSG00000253729homo_sapiensENSP0000031342067.369252.4952neolamprologus_brichardiENSNBRP0000001656473.299957.1165
ENSG00000253729homo_sapiensENSP0000031342073.643459.1328naja_najaENSNNAP0000002596580.31764.4914
ENSG00000253729homo_sapiensENSP0000031342081.056266.812podarcis_muralisENSPMRP0000000715082.515468.0148
ENSG00000253729homo_sapiensENSP0000031342081.492266.8605geospiza_fortisENSGFOP0000001429381.928967.2187
ENSG00000253729homo_sapiensENSP0000031342081.976766.9574taeniopygia_guttataENSTGUP0000001122881.877666.8764
ENSG00000253729homo_sapiensENSP0000031342073.885758.3091erpetoichthys_calabaricusENSECRP0000000995476.845660.645
ENSG00000253729homo_sapiensENSP0000031342071.778155.6202kryptolebias_marmoratusENSKMAP0000000451473.178656.7054
ENSG00000253729homo_sapiensENSP0000031342081.952566.9574salvator_merianaeENSSMRP0000001419281.89366.9087
ENSG00000253729homo_sapiensENSP0000031342071.681255.5233amphilophus_citrinellusENSACIP0000002554173.242656.7327
ENSG00000253729homo_sapiensENSP0000031342073.376956.4922dicentrarchus_labraxENSDLAP0000506866073.662556.7121
ENSG00000253729homo_sapiensENSP0000031342070.276254.53amphiprion_perculaENSAPEP0000001161574.537557.8366
ENSG00000253729homo_sapiensENSP0000031342084.278170.8091pelodiscus_sinensisENSPSIP0000001977584.176170.7234
ENSG00000253729homo_sapiensENSP0000031342077.059165.0194gopherus_evgoodeiENSGEVP0000501690984.691271.459
ENSG00000253729homo_sapiensENSP0000031342083.672570.4215chelonoidis_abingdoniiENSCABP0000000344884.408671.0411
ENSG00000253729homo_sapiensENSP0000031342071.535955.3295seriola_dumeriliENSSDUP0000000824874.968357.9843
ENSG00000253729homo_sapiensENSP0000031342070.179354.53cottoperca_gobioENSCGOP0000002766173.583957.1755
ENSG00000253729homo_sapiensENSP0000031342081.782968.2171struthio_camelus_australisENSSCUP0000001847282.56368.8677
ENSG00000253729homo_sapiensENSP0000031342080.717167.0785anser_brachyrhynchusENSABRP0000001782481.586767.8012
ENSG00000253729homo_sapiensENSP0000031342072.31156.2258gasterosteus_aculeatusENSGACP0000000258572.87656.665
ENSG00000253729homo_sapiensENSP0000031342068.144452.7859cynoglossus_semilaevisENSCSEP0000002086474.457457.676
ENSG00000253729homo_sapiensENSP0000031342073.134756.3227poecilia_formosaENSPFOP0000002283773.294556.4457
ENSG00000253729homo_sapiensENSP0000031342071.075653.7548myripristis_murdjanENSMMDP0000502216072.569954.885
ENSG00000253729homo_sapiensENSP0000031342070.373154.7238sander_luciopercaENSSLUP0000001979773.73157.335
ENSG00000253729homo_sapiensENSP0000031342082.558168.2171strigops_habroptilaENSSHBP0000500508782.498268.1675
ENSG00000253729homo_sapiensENSP0000031342070.760754.5543amphiprion_ocellarisENSAOCP0000000921974.363557.332
ENSG00000253729homo_sapiensENSP0000031342077.277164.2926terrapene_carolina_triunguisENSTMTP0000001622982.578368.7031
ENSG00000253729homo_sapiensENSP0000031342072.359556.0078hucho_huchoENSHHUP0000004524775.677758.5761
ENSG00000253729homo_sapiensENSP0000031342073.691957.0736pygocentrus_nattereriENSPNAP0000003228074.358357.5898
ENSG00000253729homo_sapiensENSP0000031342071.269455.1599anabas_testudineusENSATEP0000003153473.678957.0248
ENSG00000253729homo_sapiensENSP0000031342010.22296.68605ciona_savignyiENSCSAVP0000001970060.11439.3162
ENSG00000253729homo_sapiensENSP0000031342072.529155.6202seriola_lalandi_dorsalisENSSLDP0000001084173.925956.6914
ENSG00000253729homo_sapiensENSP0000031342072.601755.8382labrus_bergyltaENSLBEP0000003844373.582156.5922
ENSG00000253729homo_sapiensENSP0000031342070.300454.2151pundamilia_nyerereiENSPNYP0000002568672.951256.2594
ENSG00000253729homo_sapiensENSP0000031342068.628952.9312mastacembelus_armatusENSMAMP0000003463173.223156.4745
ENSG00000253729homo_sapiensENSP0000031342070.082454.7723stegastes_partitusENSSPAP0000001302174.504258.2282
ENSG00000253729homo_sapiensENSP0000031342073.425456.686oncorhynchus_tshawytschaENSOTSP0000509408274.950557.8635
ENSG00000253729homo_sapiensENSP0000031342073.425456.686oncorhynchus_tshawytschaENSOTSP0000509515874.950557.8635
ENSG00000253729homo_sapiensENSP0000031342072.892456.2258acanthochromis_polyacanthusENSAPOP0000000682373.822456.9431
ENSG00000253729homo_sapiensENSP0000031342081.855667.9021aquila_chrysaetos_chrysaetosENSACCP0002000698881.697367.7708
ENSG00000253729homo_sapiensENSP0000031342069.791754.312cyprinodon_variegatusENSCVAP0000000340374.40657.9029
ENSG00000253729homo_sapiensENSP0000031342072.432255.1599denticeps_clupeoidesENSDCDP0000000256574.304256.5855
ENSG00000253729homo_sapiensENSP0000031342073.328556.8314larimichthys_croceaENSLCRP0000505827773.955557.3174
ENSG00000253729homo_sapiensENSP0000031342071.002953.5126takifugu_rubripesENSTRUP0000004464071.279253.7208
ENSG00000253729homo_sapiensENSP0000031342081.2566.5213ficedula_albicollisENSFALP0000002127881.745166.9266
ENSG00000253729homo_sapiensENSP0000031342068.53252.5678hippocampus_comesENSHCOP0000000900872.724955.7841
ENSG00000253729homo_sapiensENSP0000031342074.055257.0494cyprinus_carpio_carpioENSCCRP0000010901974.21757.1741
ENSG00000253729homo_sapiensENSP0000031342069.71953.4641cyprinus_carpio_carpioENSCCRP0000011181973.455856.3298
ENSG00000253729homo_sapiensENSP0000031342082.146368.1202coturnix_japonicaENSCJPP0000501217582.086768.0707
ENSG00000253729homo_sapiensENSP0000031342071.027154.8934poecilia_latipinnaENSPLAP0000002297073.612956.8918
ENSG00000253729homo_sapiensENSP0000031342071.390555.0872sinocyclocheilus_grahamiENSSGRP0000009565474.702257.6426
ENSG00000253729homo_sapiensENSP0000031342072.141555.8382maylandia_zebraENSMZEP0000501538873.440256.8434
ENSG00000253729homo_sapiensENSP0000031342048.110535.8769tetraodon_nigroviridisENSTNIP0000001006062.907846.9116
ENSG00000253729homo_sapiensENSP0000031342071.414755.6202paramormyrops_kingsleyaeENSPKIP0000003264376.116759.2822
ENSG00000253729homo_sapiensENSP0000031342072.480655.7413scleropages_formosusENSSFOP0001500162475.574658.1207
ENSG00000253729homo_sapiensENSP0000031342077.543661.8459leptobrachium_leishanenseENSLLEP0000002993978.455962.5735
ENSG00000253729homo_sapiensENSP0000031342070.300453.9971scophthalmus_maximusENSSMAP0000003898874.030656.8622

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0000460involved_in maturation of 5.8S rRNA1IDAHomo_sapiens(9606)Process
GO:0000723involved_in telomere maintenance1IBAHomo_sapiens(9606)Process
GO:0000781located_in chromosome, telomeric region1HDAHomo_sapiens(9606)Component
GO:0000785part_of chromatin1IDAHomo_sapiens(9606)Component
GO:0001756involved_in somitogenesis1IEAHomo_sapiens(9606)Process
GO:0001933involved_in negative regulation of protein phosphorylation1ISSHomo_sapiens(9606)Process
GO:0002218involved_in activation of innate immune response1IDAHomo_sapiens(9606)Process
GO:0002326involved_in B cell lineage commitment1IEAHomo_sapiens(9606)Process
GO:0002327involved_in immature B cell differentiation1IEAHomo_sapiens(9606)Process
GO:0002328involved_in pro-B cell differentiation1IEAHomo_sapiens(9606)Process
GO:0002360involved_in T cell lineage commitment1IEAHomo_sapiens(9606)Process
GO:0003690enables double-stranded DNA binding1IDAHomo_sapiens(9606)Function
GO:0003723enables RNA binding1HDAHomo_sapiens(9606)Function
GO:0004672enables protein kinase activity2IDA,IMPHomo_sapiens(9606)Function
GO:0004674enables protein serine/threonine kinase activity3IBA,IDA,TASHomo_sapiens(9606)Function
GO:0004677enables DNA-dependent protein kinase activity1IDAHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005524enables ATP binding1IEAHomo_sapiens(9606)Function
GO:0005634is_active_in nucleus2IBA,IDAHomo_sapiens(9606)Component
GO:0005654located_in nucleoplasm2IDA,TASHomo_sapiens(9606)Component
GO:0005667part_of transcription regulator complex1IDAHomo_sapiens(9606)Component
GO:0005730located_in nucleolus1IDAHomo_sapiens(9606)Component
GO:0005829located_in cytosol1TASHomo_sapiens(9606)Component
GO:0005958part_of DNA-dependent protein kinase-DNA ligase 4 complex1IDAHomo_sapiens(9606)Component
GO:0006302involved_in double-strand break repair2IBA,IMPHomo_sapiens(9606)Process
GO:0006303involved_in double-strand break repair via nonhomologous end joining2NAS,TASHomo_sapiens(9606)Process
GO:0006468involved_in protein phosphorylation3IBA,IDA,IMPHomo_sapiens(9606)Process
GO:0006974involved_in DNA damage response1IDAHomo_sapiens(9606)Process
GO:0007420involved_in brain development1IEAHomo_sapiens(9606)Process
GO:0007507involved_in heart development1IEAHomo_sapiens(9606)Process
GO:0008630involved_in intrinsic apoptotic signaling pathway in response to DNA damage1IBAHomo_sapiens(9606)Process
GO:0010332involved_in response to gamma radiation1IEAHomo_sapiens(9606)Process
GO:0016020located_in membrane1HDAHomo_sapiens(9606)Component
GO:0016233involved_in telomere capping1IMPHomo_sapiens(9606)Process
GO:0018105acts_upstream_of_or_within peptidyl-serine phosphorylation2IDAHomo_sapiens(9606)Process
GO:0018107involved_in peptidyl-threonine phosphorylation1IDAHomo_sapiens(9606)Process
GO:0019899enables enzyme binding1IEAHomo_sapiens(9606)Function
GO:0019904enables protein domain specific binding1IPIHomo_sapiens(9606)Function
GO:0031571involved_in mitotic G1 DNA damage checkpoint signaling1IMPHomo_sapiens(9606)Process
GO:0031648involved_in protein destabilization1IEAHomo_sapiens(9606)Process
GO:0032040part_of small-subunit processome1IDAHomo_sapiens(9606)Component
GO:0032869involved_in cellular response to insulin stimulus1IMPHomo_sapiens(9606)Process
GO:0032991part_of protein-containing complex1IMPHomo_sapiens(9606)Component
GO:0032993part_of protein-DNA complex1IDAHomo_sapiens(9606)Component
GO:0033077involved_in T cell differentiation in thymus1IEAHomo_sapiens(9606)Process
GO:0033152involved_in immunoglobulin V(D)J recombination1IBAHomo_sapiens(9606)Process
GO:0033153involved_in T cell receptor V(D)J recombination1IEAHomo_sapiens(9606)Process
GO:0034462involved_in small-subunit processome assembly1IDAHomo_sapiens(9606)Process
GO:0034511enables U3 snoRNA binding1IDAHomo_sapiens(9606)Function
GO:0035234involved_in ectopic germ cell programmed cell death1IEAHomo_sapiens(9606)Process
GO:0036211involved_in protein modification process1TASHomo_sapiens(9606)Process
GO:0042752involved_in regulation of circadian rhythm1ISSHomo_sapiens(9606)Process
GO:0043065involved_in positive regulation of apoptotic process1IEAHomo_sapiens(9606)Process
GO:0043066involved_in negative regulation of apoptotic process1IMPHomo_sapiens(9606)Process
GO:0045087involved_in innate immune response1IEAHomo_sapiens(9606)Process
GO:0045621involved_in positive regulation of lymphocyte differentiation1ISSHomo_sapiens(9606)Process
GO:0045648involved_in positive regulation of erythrocyte differentiation1ISSHomo_sapiens(9606)Process
GO:0045727involved_in positive regulation of translation1ISSHomo_sapiens(9606)Process
GO:0045824involved_in negative regulation of innate immune response1IDAHomo_sapiens(9606)Process
GO:0045944involved_in positive regulation of transcription by RNA polymerase II1IMPHomo_sapiens(9606)Process
GO:0048511involved_in rhythmic process1IEAHomo_sapiens(9606)Process
GO:0048660involved_in regulation of smooth muscle cell proliferation1IMPHomo_sapiens(9606)Process
GO:0050678involved_in regulation of epithelial cell proliferation1IMPHomo_sapiens(9606)Process
GO:0061629enables RNA polymerase II-specific DNA-binding transcription factor binding1IPIHomo_sapiens(9606)Function
GO:0070418part_of DNA-dependent protein kinase complex1IPIHomo_sapiens(9606)Component
GO:0070419part_of nonhomologous end joining complex1IDAHomo_sapiens(9606)Component
GO:0097681involved_in double-strand break repair via alternative nonhomologous end joining1TASHomo_sapiens(9606)Process
GO:0106310enables protein serine kinase activity1IEAHomo_sapiens(9606)Function
GO:1902036involved_in regulation of hematopoietic stem cell differentiation1ISSHomo_sapiens(9606)Process
GO:1905221involved_in positive regulation of platelet formation1ISSHomo_sapiens(9606)Process
GO:2001034involved_in positive regulation of double-strand break repair via nonhomologous end joining1IDAHomo_sapiens(9606)Process

Expression