RBP Type
Canonical_RBPs
Diseases
Drug
N.A.
Main interacting RNAs
N.A.
Moonlighting functions
N.A.
Localizations
Stress granucle
BulkPerturb-seq
Ensembl ID ENSG00000244509 Gene ID
27350 Accession
17353
Symbol
APOBEC3C
Alias
A3C;PBI;ARP5;ARDC2;ARDC4;APOBEC1L;bK150C2.3
Full Name
apolipoprotein B mRNA editing enzyme catalytic subunit 3C
Status
Confidence
Length
6096 bases
Strand
Plus strand
Position
22 : 39014257 - 39020352
RNA binding domain
APOBEC_N , APOBEC_C
Summary
This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control. [provided by RefSeq, Jul 2008]
RNA binding domains (RBDs)
Protein
Domain
Pfam ID
E-value
Domain number
ENSP00000355340
APOBEC_N
PF08210 3.4e-60
1
ENSP00000355340
APOBEC_C
PF05240 4.7e-32
2
RNA binding proteomes (RBPomes)
Pubmed ID
Full Name
Cell
Author
Time
Doi
Literatures on RNA binding capacity
Pubmed ID
Title
Author
Time
Journal
Name
Transcript ID
bp
Protein
Translation ID
APOBEC3C-201
ENST00000361441
2644
190aa
ENSP00000355340
APOBEC3C-202
ENST00000428892
1056
61aa
ENSP00000390855
Pathway ID
Pathway Name
Source
ensgID
Trait
pValue
Pubmed ID
ensgID SNP Chromosome Position
Trait PubmedID Or or BEAT
EFO ID
Protein-Protein Interaction (PPI)
Ensembl ID
Source
Target
Species
Protein ID
Perc_pos
Perc_id
Species
Protein ID
Perc_pos
Perc_id
ENSG00000244509 homo_sapiens ENSP00000229335 49.4949 38.8889 homo_sapiens ENSP00000355340 51.5789 40.5263 ENSG00000244509 homo_sapiens ENSP00000385057 28.3854 20.0521 homo_sapiens ENSP00000355340 57.3684 40.5263 ENSG00000244509 homo_sapiens ENSP00000411754 48.6339 35.5191 homo_sapiens ENSP00000355340 46.8421 34.2105 ENSG00000244509 homo_sapiens ENSP00000249116 47.7387 36.1809 homo_sapiens ENSP00000355340 50 37.8947 ENSG00000244509 homo_sapiens ENSP00000327459 27.2251 20.9424 homo_sapiens ENSP00000355340 54.7368 42.1053 ENSG00000244509 homo_sapiens ENSP00000229304 33.8983 20.7627 homo_sapiens ENSP00000355340 42.1053 25.7895 ENSG00000244509 homo_sapiens ENSP00000244669 41.5179 25.8929 homo_sapiens ENSP00000355340 48.9474 30.5263 ENSG00000244509 homo_sapiens ENSP00000216099 42.228 38.8601 homo_sapiens ENSP00000355340 85.7895 78.9474 ENSG00000244509 homo_sapiens ENSP00000309749 43.1635 39.6783 homo_sapiens ENSP00000355340 84.7368 77.8947
Ensembl ID
Source
Target
Species
Protein ID
Perc_pos
Perc_id
Species
Protein ID
Perc_pos
Perc_id
ENSG00000244509 homo_sapiens ENSP00000355340 89.4737 82.1053 nomascus_leucogenys ENSNLEP00000046008 89.4737 82.1053 ENSG00000244509 homo_sapiens ENSP00000355340 98.4211 97.8947 pan_paniscus ENSPPAP00000003356 98.4211 97.8947 ENSG00000244509 homo_sapiens ENSP00000355340 91.5789 85.2632 pongo_abelii ENSPPYP00000013199 91.5789 85.2632 ENSG00000244509 homo_sapiens ENSP00000355340 39.4737 26.3158 sarcophilus_harrisii ENSSHAP00000043123 26.0417 17.3611 ENSG00000244509 homo_sapiens ENSP00000355340 52.6316 37.3684 dasypus_novemcinctus ENSDNOP00000022598 28.0112 19.888 ENSG00000244509 homo_sapiens ENSP00000355340 91.0526 82.6316 cercocebus_atys ENSCATP00000041220 91.0526 82.6316 ENSG00000244509 homo_sapiens ENSP00000355340 74.7368 65.2632 macaca_fascicularis ENSMFAP00000052254 29.5833 25.8333 ENSG00000244509 homo_sapiens ENSP00000355340 92.1053 84.2105 macaca_nemestrina ENSMNEP00000045340 92.1053 84.2105 ENSG00000244509 homo_sapiens ENSP00000355340 90.5263 81.0526 papio_anubis ENSPANP00000055526 85.5721 76.6169 ENSG00000244509 homo_sapiens ENSP00000355340 91.5789 82.6316 mandrillus_leucophaeus ENSMLEP00000025602 91.5789 82.6316 ENSG00000244509 homo_sapiens ENSP00000355340 52.1053 40 vulpes_vulpes ENSVVUP00000019758 55.9322 42.9379 ENSG00000244509 homo_sapiens ENSP00000355340 62.6316 46.3158 equus_asinus ENSEASP00005058077 30.6701 22.6804 ENSG00000244509 homo_sapiens ENSP00000355340 50 36.8421 equus_asinus ENSEASP00005060941 52.7778 38.8889 ENSG00000244509 homo_sapiens ENSP00000355340 61.5789 47.3684 equus_asinus ENSEASP00005038789 36.1111 27.7778 ENSG00000244509 homo_sapiens ENSP00000355340 62.6316 47.3684 equus_asinus ENSEASP00005027361 30.6701 23.1959 ENSG00000244509 homo_sapiens ENSP00000355340 61.0526 46.8421 panthera_leo ENSPLOP00000027854 62.0321 47.5936 ENSG00000244509 homo_sapiens ENSP00000355340 60 46.8421 equus_caballus ENSECAP00000027876 19.6213 15.3184 ENSG00000244509 homo_sapiens ENSP00000355340 61.0526 46.8421 panthera_pardus ENSPPRP00000009193 62.0321 47.5936 ENSG00000244509 homo_sapiens ENSP00000355340 52.6316 41.0526 marmota_marmota_marmota ENSMMMP00000015611 49.505 38.6139 ENSG00000244509 homo_sapiens ENSP00000355340 64.7368 51.5789 balaenoptera_musculus ENSBMSP00010013859 58.2938 46.4455 ENSG00000244509 homo_sapiens ENSP00000355340 55.2632 43.6842 ursus_americanus ENSUAMP00000004887 58.9888 46.6292 ENSG00000244509 homo_sapiens ENSP00000355340 38.9474 22.1053 monodelphis_domestica ENSMODP00000040505 28.4615 16.1538 ENSG00000244509 homo_sapiens ENSP00000355340 61.5789 45.2632 sus_scrofa ENSSSCP00000038941 43.6567 32.0896 ENSG00000244509 homo_sapiens ENSP00000355340 62.6316 51.0526 microcebus_murinus ENSMICP00000044232 58.0488 47.3171 ENSG00000244509 homo_sapiens ENSP00000355340 56.8421 45.2632 ursus_maritimus ENSUMAP00000019746 51.1848 40.7583 ENSG00000244509 homo_sapiens ENSP00000355340 78.9474 69.4737 aotus_nancymaae ENSANAP00000024763 38.8601 34.1969 ENSG00000244509 homo_sapiens ENSP00000355340 76.3158 67.3684 saimiri_boliviensis_boliviensis ENSSBOP00000033207 47.6974 42.1053 ENSG00000244509 homo_sapiens ENSP00000355340 91.0526 83.1579 chlorocebus_sabaeus ENSCSAP00000002694 91.0526 83.1579 ENSG00000244509 homo_sapiens ENSP00000355340 65.7895 51.0526 carlito_syrichta ENSTSYP00000028083 67.9348 52.7174 ENSG00000244509 homo_sapiens ENSP00000355340 64.2105 52.6316 carlito_syrichta ENSTSYP00000018841 32.8841 26.9542 ENSG00000244509 homo_sapiens ENSP00000355340 63.1579 47.8947 carlito_syrichta ENSTSYP00000014121 66.2983 50.2762 ENSG00000244509 homo_sapiens ENSP00000355340 66.3158 50 prolemur_simus ENSPSMP00000006323 31.4214 23.6908 ENSG00000244509 homo_sapiens ENSP00000355340 44.2105 32.6316 pteropus_vampyrus ENSPVAP00000008915 34.2857 25.3061 ENSG00000244509 homo_sapiens ENSP00000355340 61.5789 45.2632 myotis_lucifugus ENSMLUP00000017607 37.8641 27.8317 ENSG00000244509 homo_sapiens ENSP00000355340 41.0526 25.7895 vombatus_ursinus ENSVURP00010031524 26.1745 16.443 ENSG00000244509 homo_sapiens ENSP00000355340 58.9474 49.4737 rhinolophus_ferrumequinum ENSRFEP00010002335 56.2814 47.2362 ENSG00000244509 homo_sapiens ENSP00000355340 55.7895 41.5789 neovison_vison ENSNVIP00000001831 61.6279 45.9302 ENSG00000244509 homo_sapiens ENSP00000355340 58.9474 42.1053 heterocephalus_glaber_female ENSHGLP00000060665 28.2828 20.202 ENSG00000244509 homo_sapiens ENSP00000355340 57.8947 41.0526 heterocephalus_glaber_female ENSHGLP00000057408 48.8889 34.6667 ENSG00000244509 homo_sapiens ENSP00000355340 83.6842 76.8421 rhinopithecus_bieti ENSRBIP00000013574 43.3242 39.782 ENSG00000244509 homo_sapiens ENSP00000355340 61.0526 46.3158 canis_lupus_dingo ENSCAFP00020003112 61.0526 46.3158 ENSG00000244509 homo_sapiens ENSP00000355340 41.5789 26.8421 phascolarctos_cinereus ENSPCIP00000049844 30.3846 19.6154 ENSG00000244509 homo_sapiens ENSP00000355340 50 38.4211 otolemur_garnettii ENSOGAP00000021125 27.0655 20.7977 ENSG00000244509 homo_sapiens ENSP00000355340 60 46.3158 otolemur_garnettii ENSOGAP00000015570 29.9213 23.0971 ENSG00000244509 homo_sapiens ENSP00000355340 51.5789 43.1579 otolemur_garnettii ENSOGAP00000021819 27.762 23.2295 ENSG00000244509 homo_sapiens ENSP00000355340 76.3158 66.3158 cebus_imitator ENSCCAP00000026256 65.6109 57.0136 ENSG00000244509 homo_sapiens ENSP00000355340 83.6842 76.3158 rhinopithecus_roxellana ENSRROP00000008207 42.5134 38.7701 ENSG00000244509 homo_sapiens ENSP00000355340 48.4211 38.4211 propithecus_coquereli ENSPCOP00000020218 70.229 55.7252 ENSG00000244509 homo_sapiens ENSP00000355340 49.4737 39.4737 propithecus_coquereli ENSPCOP00000012935 71.2121 56.8182 ENSG00000244509 homo_sapiens ENSP00000355340 41.5789 23.1579 callorhinchus_milii ENSCMIP00000004961 37.619 20.9524 ENSG00000244509 homo_sapiens ENSP00000355340 38.9474 24.2105 latimeria_chalumnae ENSLACP00000018020 21.5116 13.3721 ENSG00000244509 homo_sapiens ENSP00000355340 38.4211 23.1579 lepisosteus_oculatus ENSLOCP00000004258 26.7399 16.1172 ENSG00000244509 homo_sapiens ENSP00000355340 41.0526 25.2632 xenopus_tropicalis ENSXETP00000073758 35.1351 21.6216 ENSG00000244509 homo_sapiens ENSP00000355340 38.4211 23.1579 anolis_carolinensis ENSACAP00000018261 27.1375 16.3569 ENSG00000244509 homo_sapiens ENSP00000355340 35.2632 18.4211 podarcis_muralis ENSPMRP00000035742 31.9048 16.6667 ENSG00000244509 homo_sapiens ENSP00000355340 39.4737 25.2632 erpetoichthys_calabaricus ENSECRP00000021015 28.7356 18.3908 ENSG00000244509 homo_sapiens ENSP00000355340 37.8947 25.2632 paramormyrops_kingsleyae ENSPKIP00000029857 34.7826 23.1884 ENSG00000244509 homo_sapiens ENSP00000355340 40 26.8421 scleropages_formosus ENSSFOP00015009596 38.3838 25.7576
Go ID
Go term
No. evidence
Entries
Species
Category
GO:0000932 is_active_in P-body 1 IBA Homo_sapiens(9606) Component GO:0003723 enables RNA binding 2 HDA,IBA Homo_sapiens(9606) Function GO:0004126 enables cytidine deaminase activity 1 IBA Homo_sapiens(9606) Function GO:0005515 enables protein binding 1 IPI Homo_sapiens(9606) Function GO:0005634 is_active_in nucleus 2 IBA,IDA Homo_sapiens(9606) Component GO:0005737 is_active_in cytoplasm 2 IBA,IDA Homo_sapiens(9606) Component GO:0008270 enables zinc ion binding 1 IEA Homo_sapiens(9606) Function GO:0009972 involved_in cytidine deamination 1 IDA Homo_sapiens(9606) Process GO:0010526 involved_in retrotransposon silencing 1 IDA Homo_sapiens(9606) Process GO:0016554 involved_in cytidine to uridine editing 1 IBA Homo_sapiens(9606) Process GO:0044355 involved_in clearance of foreign intracellular DNA 1 IDA Homo_sapiens(9606) Process GO:0045071 involved_in negative regulation of viral genome replication 1 IDA Homo_sapiens(9606) Process GO:0045087 involved_in innate immune response 1 IEA Homo_sapiens(9606) Process GO:0045869 involved_in negative regulation of single stranded viral RNA replication via double stranded DNA intermediate 1 IBA Homo_sapiens(9606) Process GO:0047844 enables deoxycytidine deaminase activity 1 IBA Homo_sapiens(9606) Function GO:0051607 involved_in defense response to virus 1 IBA Homo_sapiens(9606) Process GO:0070383 involved_in DNA cytosine deamination 1 IBA Homo_sapiens(9606) Process GO:0080111 involved_in DNA demethylation 2 IBA,IDA Homo_sapiens(9606) Process
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