Functions and Diseases

RBP Type Canonical_RBPs
Diseases CancerFlavivirusesSARS-COV-2Dengue
Drug N.A.
Main interacting RNAs mRNA
Moonlighting functions N.A.
Localizations Stress granule or P-body
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000244462 Gene ID 10137 Accession 9898
Symbol RBM12 Alias SWAN;SCZD19;HRIHFB2091 Full Name RNA binding motif protein 12
Status Confidence Length 16032 bases Strand Minus strand
Position 20 : 35648925 - 35664956 RNA binding domain RRM_1
Summary This gene encodes a protein that contains several RNA-binding motifs, potential transmembrane domains, and proline-rich regions. This gene and the gene for copine I overlap at map location 20q11.21. Alternative splicing in the 5' UTR results in four transcript variants. All variants encode the same protein. [provided by RefSeq, Nov 2010]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000352668 RRM_1 PF00076 1.7e-29 1
ENSP00000352668 RRM_1 PF00076 1.7e-29 2
ENSP00000352668 RRM_1 PF00076 1.7e-29 3
ENSP00000363217 RRM_1 PF00076 1.7e-29 1
ENSP00000363217 RRM_1 PF00076 1.7e-29 2
ENSP00000363217 RRM_1 PF00076 1.7e-29 3
ENSP00000363228 RRM_1 PF00076 1.7e-29 1
ENSP00000363228 RRM_1 PF00076 1.7e-29 2
ENSP00000363228 RRM_1 PF00076 1.7e-29 3

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal

Transcripts

Name Transcript ID bp Protein Translation ID
RBM12-203 ENST00000374114 6646 932aa ENSP00000363228
RBM12-201 ENST00000359646 5332 932aa ENSP00000352668
RBM12-202 ENST00000374104 5213 932aa ENSP00000363217
RBM12-204 ENST00000424458 1068 291aa ENSP00000411036
RBM12-205 ENST00000431148 583 143aa ENSP00000392642
RBM12-206 ENST00000435161 565 134aa ENSP00000411692

Gene Model

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
60015Arterial Pressure1.8695450E-005-

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000244462homo_sapiensENSP0000040573825.697513.6564homo_sapiensENSP0000036322818.77689.97854
ENSG00000244462homo_sapiensENSP0000036192738.307420.49homo_sapiensENSP0000036322818.45499.87124
ENSG00000244462homo_sapiensENSP0000037708238.307420.0445homo_sapiensENSP0000036322818.45499.65665
ENSG00000244462homo_sapiensENSP0000041874824.407312.6918homo_sapiensENSP0000036322818.77689.76395
ENSG00000244462homo_sapiensENSP0000026586635.549120.8092homo_sapiensENSP0000036322813.19747.72532
ENSG00000244462homo_sapiensENSP0000042980738.361627.2727homo_sapiensENSP0000036322841.201729.2918
ENSG00000244462homo_sapiensENSP0000050778739.036120homo_sapiensENSP0000036322817.3828.90558
ENSG00000244462homo_sapiensENSP0000025479928.541716.0417homo_sapiensENSP0000036322814.69968.2618

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000244462homo_sapiensENSP0000036322899.785499.6781nomascus_leucogenysENSNLEP0000004673297.484397.3795
ENSG00000244462homo_sapiensENSP00000363228100100pan_paniscusENSPPAP0000003600397.693997.6939
ENSG00000244462homo_sapiensENSP0000036322899.892799.8927pongo_abeliiENSPPYP0000001223799.678899.6788
ENSG00000244462homo_sapiensENSP00000363228100100pan_troglodytesENSPTRP0000002306997.693997.6939
ENSG00000244462homo_sapiensENSP00000363228100100pan_troglodytesENSPTRP0000006636497.693997.6939
ENSG00000244462homo_sapiensENSP0000036322899.892799.7854gorilla_gorillaENSGGOP0000002151797.589197.4843
ENSG00000244462homo_sapiensENSP0000036322873.92765.5579ornithorhynchus_anatinusENSOANP0000004532875.382966.849
ENSG00000244462homo_sapiensENSP0000036322890.343385.9442sarcophilus_harrisiiENSSHAP0000002304195.790791.1263
ENSG00000244462homo_sapiensENSP0000036322889.914285.6223notamacropus_eugeniiENSMEUP0000000695295.662191.0959
ENSG00000244462homo_sapiensENSP0000036322859.442157.2961erinaceus_europaeusENSEEUP0000000804559.827257.6674
ENSG00000244462homo_sapiensENSP0000036322899.892799.4635cercocebus_atysENSCATP0000001369297.589197.1698
ENSG00000244462homo_sapiensENSP0000036322899.892799.4635macaca_fascicularisENSMFAP0000006205999.892799.4635
ENSG00000244462homo_sapiensENSP0000036322899.892799.5708macaca_mulattaENSMMUP0000005316399.892799.5708
ENSG00000244462homo_sapiensENSP0000036322899.892799.5708macaca_nemestrinaENSMNEP0000004576097.589197.2746
ENSG00000244462homo_sapiensENSP0000036322899.892799.5708mandrillus_leucophaeusENSMLEP0000001675597.589197.2746
ENSG00000244462homo_sapiensENSP0000036322897.532294.9571tursiops_truncatusENSTTRP0000001614997.952695.3664
ENSG00000244462homo_sapiensENSP0000036322895.386392.2747mus_spretusMGP_SPRETEiJ_P005778288.722685.8283
ENSG00000244462homo_sapiensENSP0000036322897.746895.279equus_asinusENSEASP0000505857596.606694.1675
ENSG00000244462homo_sapiensENSP0000036322896.995794.7425capra_hircusENSCHIP0000002946298.154295.874
ENSG00000244462homo_sapiensENSP0000036322897.10394.3133loxodonta_africanaENSLAFP0000000866297.416694.6179
ENSG00000244462homo_sapiensENSP0000036322897.854195.3863equus_caballusENSECAP0000008023998.275995.7974
ENSG00000244462homo_sapiensENSP0000036322896.781194.9571canis_lupus_familiarisENSCAFP0084503076098.257196.4052
ENSG00000244462homo_sapiensENSP0000036322897.317695.1717cavia_porcellusENSCPOP0000002463790.881888.8778
ENSG00000244462homo_sapiensENSP0000036322897.746895.4936ursus_americanusENSUAMP0000001293098.380196.1123
ENSG00000244462homo_sapiensENSP0000036322897.210394.6352bison_bison_bisonENSBBBP0000002291795.068292.5498
ENSG00000244462homo_sapiensENSP0000036322897.746895.3863sus_scrofaENSSSCP0000002508093.820891.5551
ENSG00000244462homo_sapiensENSP0000036322889.163186.4807microcebus_murinusENSMICP0000003187792.95390.1566
ENSG00000244462homo_sapiensENSP0000036322896.244694.6352microcebus_murinusENSMICP0000000680396.244694.6352
ENSG00000244462homo_sapiensENSP0000036322896.0392.8112octodon_degusENSODEP0000001881891.419888.3555
ENSG00000244462homo_sapiensENSP0000036322880.79476.824jaculus_jaculusENSJJAP0000000489390.071885.6459
ENSG00000244462homo_sapiensENSP0000036322896.459293.133ochotona_princepsENSOPRP0000000521295.740292.4388
ENSG00000244462homo_sapiensENSP0000036322895.27992.382mus_caroliMGP_CAROLIEiJ_P005563488.182785.5015
ENSG00000244462homo_sapiensENSP0000036322890.879887.6609dipodomys_ordiiENSDORP0000000056489.915186.7304
ENSG00000244462homo_sapiensENSP0000036322896.995794.4206dipodomys_ordiiENSDORP0000002125591.313188.8889
ENSG00000244462homo_sapiensENSP0000036322827.575127.2532mustela_putorius_furoENSMPUP0000001896896.616595.4887
ENSG00000244462homo_sapiensENSP0000036322896.781194.6352mustela_putorius_furoENSMPUP0000001767797.724895.558
ENSG00000244462homo_sapiensENSP0000036322899.141698.3906aotus_nancymaaeENSANAP0000003009096.95796.2225
ENSG00000244462homo_sapiensENSP0000036322898.92798.2833saimiri_boliviensis_boliviensisENSSBOP0000002241296.747196.1175
ENSG00000244462homo_sapiensENSP0000036322887.660985.3004vicugna_pacosENSVPAP0000000353988.707986.3192
ENSG00000244462homo_sapiensENSP0000036322896.351993.133mesocricetus_auratusENSMAUP0000001249690.070287.0612
ENSG00000244462homo_sapiensENSP0000036322897.639595.0644phocoena_sinusENSPSNP0000001274798.060395.4741
ENSG00000244462homo_sapiensENSP0000036322895.386394.5279carlito_syrichtaENSTSYP0000003190396.212195.3463
ENSG00000244462homo_sapiensENSP0000036322895.493692.0601rattus_norvegicusENSRNOP0000002670086.240383.1395
ENSG00000244462homo_sapiensENSP0000036322895.708292.1674microtus_ochrogasterENSMOCP0000001301789.285.9
ENSG00000244462homo_sapiensENSP0000036322884.227581.867peromyscus_maniculatus_bairdiiENSPEMP0000001948989.204586.7045
ENSG00000244462homo_sapiensENSP0000036322896.0392.5966cricetulus_griseus_chok1gshdENSCGRP0000102266690.40487.1717
ENSG00000244462homo_sapiensENSP0000036322897.10394.8498pteropus_vampyrusENSPVAP0000001407897.521695.2586
ENSG00000244462homo_sapiensENSP0000036322897.532294.5279myotis_lucifugusENSMLUP0000001021195.684292.7368
ENSG00000244462homo_sapiensENSP0000036322897.639595.1717bos_taurusENSBTAP0000005342795.487993.0745
ENSG00000244462homo_sapiensENSP0000036322889.699686.588heterocephalus_glaber_femaleENSHGLP0000001843195.32592.0182
ENSG00000244462homo_sapiensENSP0000036322899.785499.5708rhinopithecus_bietiENSRBIP0000003897897.484397.2746
ENSG00000244462homo_sapiensENSP0000036322896.781194.9571canis_lupus_dingoENSCAFP0002000695698.257196.4052
ENSG00000244462homo_sapiensENSP0000036322895.708292.5966procavia_capensisENSPCAP0000000806396.641493.4995
ENSG00000244462homo_sapiensENSP0000036322896.673893.7768nannospalax_galiliENSNGAP0000001458190.826688.1048
ENSG00000244462homo_sapiensENSP0000036322896.781194.3133chinchilla_lanigeraENSCLAP0000002508892.798490.4321
ENSG00000244462homo_sapiensENSP0000036322894.849892.8112ictidomys_tridecemlineatusENSSTOP0000001878295.774793.7161
ENSG00000244462homo_sapiensENSP0000036322880.901379.721cebus_imitatorENSCCAP0000003596696.666795.2564
ENSG00000244462homo_sapiensENSP0000036322893.562292.1674cebus_imitatorENSCCAP0000003634896.781495.3385
ENSG00000244462homo_sapiensENSP0000036322893.562291.6309urocitellus_parryiiENSUPAP0001000489997.104795.1002
ENSG00000244462homo_sapiensENSP0000036322899.785499.5708rhinopithecus_roxellanaENSRROP0000002746697.484397.2746
ENSG00000244462homo_sapiensENSP0000036322895.922792.7039mus_pahariMGP_PahariEiJ_P006661088.778585.7994
ENSG00000244462homo_sapiensENSP0000036322897.746896.1373propithecus_coquereliENSPCOP0000002318396.09794.5148
ENSG00000244462homo_sapiensENSP0000036322814.37778.69099caenorhabditis_elegansY73B6BL.33a.121.967213.2787
ENSG00000244462homo_sapiensENSP0000036322824.892713.6266caenorhabditis_elegansY106G6D.7.124.472613.3966
ENSG00000244462homo_sapiensENSP0000036322815.66528.15451caenorhabditis_elegansZK1067.6a.123.624612.2977
ENSG00000244462homo_sapiensENSP0000036322814.59238.47639drosophila_melanogasterFBpp042843423.208213.4812
ENSG00000244462homo_sapiensENSP0000036322817.27478.90558drosophila_melanogasterFBpp008647916.64948.58325
ENSG00000244462homo_sapiensENSP0000036322832.510720.8155ciona_intestinalisENSCINP0000000212528.18618.0465
ENSG00000244462homo_sapiensENSP0000036322817.811210.0858ciona_intestinalisENSCINP0000003370422.462812.7199
ENSG00000244462homo_sapiensENSP0000036322838.197428.0043eptatretus_burgeriENSEBUP0000002742463.232746.3588
ENSG00000244462homo_sapiensENSP0000036322868.562256.6524callorhinchus_miliiENSCMIP0000001029576.25363.0072
ENSG00000244462homo_sapiensENSP0000036322870.922758.9056lepisosteus_oculatusENSLOCP0000002246474.020261.4782
ENSG00000244462homo_sapiensENSP0000036322866.201754.3991danio_rerioENSDARP0000013678270.433857.8767
ENSG00000244462homo_sapiensENSP0000036322865.236154.3991carassius_auratusENSCARP0000008139169.885158.2759
ENSG00000244462homo_sapiensENSP0000036322865.128853.8627carassius_auratusENSCARP0000008916069.930957.8341
ENSG00000244462homo_sapiensENSP0000036322865.557953.3262ictalurus_punctatusENSIPUP0000002137668.344555.5928
ENSG00000244462homo_sapiensENSP0000036322862.124549.7854oncorhynchus_kisutchENSOKIP0000503700463.347950.7659
ENSG00000244462homo_sapiensENSP0000036322864.055852.1459oncorhynchus_kisutchENSOKIP0000506454268.306655.6064
ENSG00000244462homo_sapiensENSP0000036322864.055852.1459oncorhynchus_mykissENSOMYP0000001234968.306655.6064
ENSG00000244462homo_sapiensENSP0000036322860.407747.3176salmo_salarENSSSAP0000017737347.271237.0277
ENSG00000244462homo_sapiensENSP0000036322863.519352.3605salmo_salarENSSSAP0000017624669.811357.5472
ENSG00000244462homo_sapiensENSP0000036322828.862725salmo_truttaENSSTUP0000006500473.698663.8356
ENSG00000244462homo_sapiensENSP0000036322863.519352.3605salmo_truttaENSSTUP0000007942969.811357.5472
ENSG00000244462homo_sapiensENSP0000036322860.407747.7468salmo_truttaENSSTUP0000006501848.576438.3952
ENSG00000244462homo_sapiensENSP0000036322860.622348.0687cyclopterus_lumpusENSCLMP0000504722062.708149.7225
ENSG00000244462homo_sapiensENSP0000036322862.231849.2489lates_calcariferENSLCAP0001001135264.301650.8869
ENSG00000244462homo_sapiensENSP0000036322874.678161.9099xenopus_tropicalisENSXETP0000010684979.090965.5682
ENSG00000244462homo_sapiensENSP0000036322887.768279.5064laticauda_laticaudataENSLLTP0000001136492.954584.2045
ENSG00000244462homo_sapiensENSP0000036322887.660979.2918notechis_scutatusENSNSUP0000002083292.840983.9773
ENSG00000244462homo_sapiensENSP0000036322887.768279.2918pseudonaja_textilisENSPTXP0000000201192.954583.9773
ENSG00000244462homo_sapiensENSP0000036322887.660980.3648gallus_gallusENSGALP0001003572392.840985.1136
ENSG00000244462homo_sapiensENSP0000036322887.446480.4721meleagris_gallopavoENSMGAP0000000096092.613685.2273
ENSG00000244462homo_sapiensENSP0000036322886.58879.1845serinus_canariaENSSCAP0000001667991.186483.3898
ENSG00000244462homo_sapiensENSP0000036322887.339180.1502parus_majorENSPMJP0000000153592.605284.9829
ENSG00000244462homo_sapiensENSP0000036322887.768279.3991naja_najaENSNNAP0000002568192.954584.0909
ENSG00000244462homo_sapiensENSP0000036322887.231879.5064podarcis_muralisENSPMRP0000001351292.386484.2045
ENSG00000244462homo_sapiensENSP0000036322887.231879.721taeniopygia_guttataENSTGUP0000002770692.491584.5279
ENSG00000244462homo_sapiensENSP0000036322862.660949.3562amphilophus_citrinellusENSACIP0000001420065.033451.2249
ENSG00000244462homo_sapiensENSP0000036322861.051548.6051dicentrarchus_labraxENSDLAP0000506685563.152150.2775
ENSG00000244462homo_sapiensENSP0000036322882.61876.2876pelodiscus_sinensisENSPSIP0000000803386.322979.7085
ENSG00000244462homo_sapiensENSP0000036322888.197481.5451gopherus_evgoodeiENSGEVP0000502330593.621986.5604
ENSG00000244462homo_sapiensENSP0000036322887.660980.9013chelonoidis_abingdoniiENSCABP0000000387291.489484.4345
ENSG00000244462homo_sapiensENSP0000036322888.304781.4378struthio_camelus_australisENSSCUP0000001575093.629186.3481
ENSG00000244462homo_sapiensENSP0000036322861.158848.176gasterosteus_aculeatusENSGACP0000000552961.822148.6985
ENSG00000244462homo_sapiensENSP0000036322849.463539.3777poecilia_formosaENSPFOP0000002950164.656451.4727
ENSG00000244462homo_sapiensENSP0000036322862.017249.1416myripristis_murdjanENSMMDP0000502331664.079850.7761
ENSG00000244462homo_sapiensENSP0000036322860.407747.9614sander_luciopercaENSSLUP0000005095762.834849.8884
ENSG00000244462homo_sapiensENSP0000036322887.768280.1502strigops_habroptilaENSSHBP0000502074392.954584.8864
ENSG00000244462homo_sapiensENSP0000036322862.124549.3562amphiprion_ocellarisENSAOCP0000002933664.333351.1111
ENSG00000244462homo_sapiensENSP0000036322888.197481.3305terrapene_carolina_triunguisENSTMTP0000002719193.621986.3326
ENSG00000244462homo_sapiensENSP0000036322863.626652.1459hucho_huchoENSHHUP0000000418968.713856.3152
ENSG00000244462homo_sapiensENSP0000036322862.446450.1073hucho_huchoENSHHUP0000003616161.652549.4703
ENSG00000244462homo_sapiensENSP0000036322861.695349.0343betta_splendensENSBSLP0000004221164.031250.8909
ENSG00000244462homo_sapiensENSP0000036322832.61821.1373ciona_savignyiENSCSAVP0000000158729.485919.1077
ENSG00000244462homo_sapiensENSP000003632288.798284.61373ciona_savignyiENSCSAVP0000001845129.390715.4122
ENSG00000244462homo_sapiensENSP0000036322816.84559.97854ciona_savignyiENSCSAVP0000000345822.786613.4978
ENSG00000244462homo_sapiensENSP0000036322863.948552.0386oncorhynchus_tshawytschaENSOTSP0000505404868.192255.492
ENSG00000244462homo_sapiensENSP0000036322862.231849.7854oncorhynchus_tshawytschaENSOTSP0000505417167.05253.6416
ENSG00000244462homo_sapiensENSP0000036322887.660980.2575aquila_chrysaetos_chrysaetosENSACCP0002000586592.735584.9035
ENSG00000244462homo_sapiensENSP0000036322861.802648.4979nothobranchius_furzeriENSNFUP000150299266450.2222
ENSG00000244462homo_sapiensENSP0000036322861.695347.7468takifugu_rubripesENSTRUP0000008314664.679450.0562
ENSG00000244462homo_sapiensENSP0000036322887.339179.721ficedula_albicollisENSFALP0000001305992.605284.5279
ENSG00000244462homo_sapiensENSP0000036322865.236154.3991cyprinus_carpio_carpioENSCCRP0000017905469.248357.7449
ENSG00000244462homo_sapiensENSP0000036322865.343354.3991cyprinus_carpio_carpioENSCCRP0000016991170.242258.4775
ENSG00000244462homo_sapiensENSP0000036322865.772554.721sinocyclocheilus_grahamiENSSGRP0000010809270.217658.4192
ENSG00000244462homo_sapiensENSP0000036322865.236154.2918sinocyclocheilus_grahamiENSSGRP0000001307069.565257.8947
ENSG00000244462homo_sapiensENSP0000036322860.51547.9614oryzias_melastigmaENSOMEP0000002642262.666749.6667

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0003723enables RNA binding2HDA,IBAHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005654is_active_in nucleoplasm2IBA,IDAHomo_sapiens(9606)Component
GO:0043484involved_in regulation of RNA splicing1IBAHomo_sapiens(9606)Process
GO:1990904part_of ribonucleoprotein complex1IBAHomo_sapiens(9606)Component

Expression