Functions and Diseases

RBP Type Canonical_RBPs
Diseases N.A.
Drug N.A.
Main interacting RNAs mRNA
Moonlighting functions N.A.
Localizations Nucleoli
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000244395 Gene ID 378949 Accession 23915
Symbol RBMY1D Alias RBM1;RBM2;YRRM1;YRRM2;hRBMY;RBMY1A1 Full Name RNA binding motif protein Y-linked family 1 member D
Status Confidence Length 14451 bases Strand Minus strand
Position Y : 21880076 - 21894526 RNA binding domain RBM1CTR , RRM_1
Summary This gene encodes a protein containing an RNA-binding motif in the N-terminus and four SRGY (serine, arginine, glycine, tyrosine) boxes in the C-terminus. This protein likely functions as a splicing factor during spermatogenesis. Multiple closely related paralogs of this gene are found in a gene cluster in the AZFb azoospermia factor region of chromosome Y. Most of these related copies are thought to be pseudogenes, though several likely encode functional proteins. [provided by RefSeq, Mar 2016]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000399181 RRM_1 PF00076 6.2e-21 1
ENSP00000399181 RBM1CTR PF08081 2.1e-21 2
ENSP00000372127 RRM_1 PF00076 7e-21 1
ENSP00000372127 RBM1CTR PF08081 2.3e-21 2
ENSP00000372099 RRM_1 PF00076 9.4e-21 1

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal

Transcripts

Name Transcript ID bp Protein Translation ID
RBMY1D-201 ENST00000382653 1718 81aa ENSP00000372099
RBMY1D-202 ENST00000382680 1921 496aa ENSP00000372127
RBMY1D-203 ENST00000418956 1491 459aa ENSP00000399181

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000244395homo_sapiensENSP0000029597112.98487.75717homo_sapiensENSP0000037212715.52429.27419
ENSG00000244395homo_sapiensENSP0000030413959.693948.2143homo_sapiensENSP0000037212747.177438.1048
ENSG00000244395homo_sapiensENSP0000041745118.837914.433homo_sapiensENSP0000037212740.524231.0484
ENSG00000244395homo_sapiensENSP0000047869134.604120.2346homo_sapiensENSP0000037212723.790313.9113
ENSG00000244395homo_sapiensENSP0000044536613.31447.64873homo_sapiensENSP000003721279.475815.44355
ENSG00000244395homo_sapiensENSP0000034182633.87119.6237homo_sapiensENSP0000037212725.403214.7177
ENSG00000244395homo_sapiensENSP0000035009037.187522.1875homo_sapiensENSP0000037212723.991914.3145
ENSG00000244395homo_sapiensENSP0000049380538.7522.8125homo_sapiensENSP000003721272514.7177
ENSG00000244395homo_sapiensENSP0000037630932.539720.1058homo_sapiensENSP0000037212724.798415.3226
ENSG00000244395homo_sapiensENSP0000028407329.573217.378homo_sapiensENSP0000037212719.556511.4919
ENSG00000244395homo_sapiensENSP0000031047121.72712.2563homo_sapiensENSP0000037212715.72588.87097
ENSG00000244395homo_sapiensENSP0000030916621.153811.8132homo_sapiensENSP0000037212715.52428.66935
ENSG00000244395homo_sapiensENSP0000049824871.538558.7179homo_sapiensENSP0000037212756.2546.1694
ENSG00000244395homo_sapiensENSP0000035964573.657361.1253homo_sapiensENSP0000037212758.064548.1855
ENSG00000244395homo_sapiensENSP0000040137122.020711.9171homo_sapiensENSP0000037212717.13719.27419
ENSG00000244395homo_sapiensENSP0000025755227.071815.4696homo_sapiensENSP0000037212719.758111.2903
ENSG00000244395homo_sapiensENSP0000028172214.82187.31707homo_sapiensENSP0000037212715.92747.8629
ENSG00000244395homo_sapiensENSP0000035295612.98417.51708homo_sapiensENSP0000037212711.49196.65323
ENSG00000244395homo_sapiensENSP0000036293622.648113.5889homo_sapiensENSP0000037212713.10487.8629
ENSG00000244395homo_sapiensENSP0000031319926.197217.1831homo_sapiensENSP0000037212718.7512.2984
ENSG00000244395homo_sapiensENSP0000025336311.50947.16981homo_sapiensENSP0000037212712.29847.66129
ENSG00000244395homo_sapiensENSP0000036310913.13997.67918homo_sapiensENSP0000037212715.52429.07258
ENSG00000244395homo_sapiensENSP0000031604232.131120.6557homo_sapiensENSP0000037212719.758112.7016
ENSG00000244395homo_sapiensENSP0000031819512.11276.33803homo_sapiensENSP0000037212717.33879.07258
ENSG00000244395homo_sapiensENSP0000039490222.411.4667homo_sapiensENSP0000037212716.93558.66935
ENSG00000244395homo_sapiensENSP0000035110827.108417.1687homo_sapiensENSP0000037212718.145211.4919
ENSG00000244395homo_sapiensENSP000002617419.68754.58333homo_sapiensENSP0000037212718.758.87097
ENSG00000244395homo_sapiensENSP0000023307831.203918.6732homo_sapiensENSP0000037212725.604815.3226
ENSG00000244395homo_sapiensENSP0000029547020.238112.1429homo_sapiensENSP0000037212717.137110.2823
ENSG00000244395homo_sapiensENSP0000046602539.057228.2828homo_sapiensENSP0000037212723.387116.9355
ENSG00000244395homo_sapiensENSP0000036595063.694348.4076homo_sapiensENSP0000037212720.161315.3226
ENSG00000244395homo_sapiensENSP0000037210510099.7984homo_sapiensENSP0000037212710099.7984
ENSG00000244395homo_sapiensENSP0000037248499.798499.7984homo_sapiensENSP0000037212799.798499.7984
ENSG00000244395homo_sapiensENSP0000037215499.798499.7984homo_sapiensENSP0000037212799.798499.7984
ENSG00000244395homo_sapiensENSP0000030715598.991998.9919homo_sapiensENSP0000037212798.991998.9919
ENSG00000244395homo_sapiensENSP0000025083198.991998.9919homo_sapiensENSP0000037212798.991998.9919

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000244395homo_sapiensENSP0000037212792.943691.5323pan_troglodytesENSPTRP0000008674291.468390.0794
ENSG00000244395homo_sapiensENSP0000037212790.322688.5081pan_troglodytesENSPTRP0000008748991.056989.2276
ENSG00000244395homo_sapiensENSP0000037212794.959793.9516pan_troglodytesENSPTRP0000006512594.768693.7626
ENSG00000244395homo_sapiensENSP0000037212792.540391.7339pan_troglodytesENSPTRP0000006037194.057493.2377
ENSG00000244395homo_sapiensENSP0000037212792.741991.3306pan_troglodytesENSPTRP0000006320991.269889.881
ENSG00000244395homo_sapiensENSP0000037212794.556493.5484pan_troglodytesENSPTRP0000008668894.366293.3602
ENSG00000244395homo_sapiensENSP0000037212787.586.4919pan_troglodytesENSPTRP0000006420793.333392.2581
ENSG00000244395homo_sapiensENSP0000037212792.741991.3306pan_troglodytesENSPTRP0000006298591.269889.881
ENSG00000244395homo_sapiensENSP0000037212781.2576.0081pan_troglodytesENSPTRP0000006581985.927580.3838
ENSG00000244395homo_sapiensENSP0000037212788.104886.8952pan_troglodytesENSPTRP0000008677591.806790.5462
ENSG00000244395homo_sapiensENSP0000037212794.758193.5484pan_troglodytesENSPTRP0000007029794.188492.986
ENSG00000244395homo_sapiensENSP0000037212783.669479.8387macaca_fascicularisENSMFAP0000006008970.101366.8919
ENSG00000244395homo_sapiensENSP0000037212783.87180.0403macaca_mulattaENSMMUP0000007558766.136763.1161
ENSG00000244395homo_sapiensENSP0000037212737.534.4758macaca_mulattaENSMMUP0000004204380.519574.026
ENSG00000244395homo_sapiensENSP0000037212727.016123.9919marmota_marmota_marmotaENSMMMP0000000832081.212172.1212
ENSG00000244395homo_sapiensENSP0000037212742.741931.4516mus_musculusENSMUSP0000013952755.789541.0526
ENSG00000244395homo_sapiensENSP0000037212742.741931.4516mus_musculusENSMUSP0000014070455.789541.0526
ENSG00000244395homo_sapiensENSP0000037212742.741931.4516mus_musculusENSMUSP0000013978455.789541.0526
ENSG00000244395homo_sapiensENSP0000037212742.540331.4516mus_musculusENSMUSP0000014051255.526341.0526
ENSG00000244395homo_sapiensENSP0000037212722.580617.1371mus_musculusENSMUSP0000013996967.469951.2048
ENSG00000244395homo_sapiensENSP0000037212742.741931.6532mus_musculusENSMUSP0000014093655.789541.3158
ENSG00000244395homo_sapiensENSP0000037212742.741931.4516mus_musculusENSMUSP0000009793055.789541.0526
ENSG00000244395homo_sapiensENSP0000037212742.741931.6532mus_musculusENSMUSP0000014057555.789541.3158
ENSG00000244395homo_sapiensENSP0000037212742.741931.4516mus_musculusENSMUSP0000013965955.789541.0526
ENSG00000244395homo_sapiensENSP0000037212743.145232.0564mus_musculusENSMUSP0000014118356.315841.8421
ENSG00000244395homo_sapiensENSP0000037212771.572665.7258chlorocebus_sabaeusENSCSAP0000001431772.597166.6667
ENSG00000244395homo_sapiensENSP0000037212744.959734.0726rattus_norvegicusENSRNOP0000007464357.474243.5567
ENSG00000244395homo_sapiensENSP0000037212712.09689.27419mus_spicilegusENSMSIP000000055597557.5
ENSG00000244395homo_sapiensENSP0000037212770.362967.1371rhinopithecus_bietiENSRBIP0000000157082.701478.91
ENSG00000244395homo_sapiensENSP0000037212727.016123.5887urocitellus_parryiiENSUPAP0001001114181.212170.9091
ENSG00000244395homo_sapiensENSP0000037212770.362967.5403rhinopithecus_roxellanaENSRROP0000001067182.897979.5724
ENSG00000244395homo_sapiensENSP0000037212712.59.27419eptatretus_burgeriENSEBUP0000002406266.666749.4624
ENSG00000244395homo_sapiensENSP0000037212712.70169.67742eptatretus_burgeriENSEBUP0000001193367.021351.0638

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0003723enables RNA binding1IBAHomo_sapiens(9606)Function
GO:0005654located_in nucleoplasm1IDAHomo_sapiens(9606)Component
GO:0005681part_of spliceosomal complex1IBAHomo_sapiens(9606)Component
GO:0005730located_in nucleolus1IDAHomo_sapiens(9606)Component
GO:0006397involved_in mRNA processing1IEAHomo_sapiens(9606)Process
GO:0008380involved_in RNA splicing1IEAHomo_sapiens(9606)Process
GO:0048026involved_in positive regulation of mRNA splicing, via spliceosome1IBAHomo_sapiens(9606)Process

Expression