Functions and Diseases

RBP Type Canonical_RBPs
Diseases N.A.
Drug N.A.
Main interacting RNAs mRNA
Moonlighting functions N.A.
Localizations Nucleoli
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000242875 Gene ID 378948 Accession 23914
Symbol RBMY1B Alias RBMY1D Full Name RNA binding motif protein Y-linked family 1 member B
Status Confidence Length 14449 bases Strand Plus strand
Position Y : 21511338 - 21525786 RNA binding domain RBM1CTR , RRM_1
Summary This gene encodes a protein containing an RNA-binding motif in the N-terminus and four SRGY (serine, arginine, glycine, tyrosine) boxes in the C-terminus. This protein likely functions as a splicing factor during spermatogenesis. Multiple closely related paralogs of this gene are found in a gene cluster in the AZFb azoospermia factor region of chromosome Y. Most of these related copies are thought to be pseudogenes, though several likely encode functional proteins. [provided by RefSeq, Mar 2016]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000372484 RRM_1 PF00076 6.9e-21 1
ENSP00000372484 RBM1CTR PF08081 2.3e-21 2
ENSP00000372084 RRM_1 PF00076 9.4e-21 1

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal

Transcripts

Name Transcript ID bp Protein Translation ID
RBMY1B-202 ENST00000383020 1921 496aa ENSP00000372484
RBMY1B-201 ENST00000382639 1718 81aa ENSP00000372084

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000242875homo_sapiensENSP0000029597112.98487.75717homo_sapiensENSP0000037248415.52429.27419
ENSG00000242875homo_sapiensENSP0000030413959.94948.4694homo_sapiensENSP0000037248447.37938.3064
ENSG00000242875homo_sapiensENSP0000041745118.931614.5267homo_sapiensENSP0000037248440.725831.25
ENSG00000242875homo_sapiensENSP0000047869134.897420.5279homo_sapiensENSP0000037248423.991914.1129
ENSG00000242875homo_sapiensENSP0000044536613.59777.93201homo_sapiensENSP000003724849.677425.64516
ENSG00000242875homo_sapiensENSP0000034182634.139819.8925homo_sapiensENSP0000037248425.604814.9194
ENSG00000242875homo_sapiensENSP0000035009037.522.5homo_sapiensENSP0000037248424.193514.5161
ENSG00000242875homo_sapiensENSP0000049380539.062523.125homo_sapiensENSP0000037248425.201614.9194
ENSG00000242875homo_sapiensENSP0000037630932.804220.3704homo_sapiensENSP000003724842515.5242
ENSG00000242875homo_sapiensENSP0000028407329.87817.6829homo_sapiensENSP0000037248419.758111.6935
ENSG00000242875homo_sapiensENSP0000031047122.005612.5348homo_sapiensENSP0000037248415.92749.07258
ENSG00000242875homo_sapiensENSP0000030916621.428612.0879homo_sapiensENSP0000037248415.72588.87097
ENSG00000242875homo_sapiensENSP0000049824871.794958.9744homo_sapiensENSP0000037248456.451646.371
ENSG00000242875homo_sapiensENSP0000035964573.91361.3811homo_sapiensENSP0000037248458.266148.3871
ENSG00000242875homo_sapiensENSP0000040137122.020711.9171homo_sapiensENSP0000037248417.13719.27419
ENSG00000242875homo_sapiensENSP0000025755227.348115.7459homo_sapiensENSP0000037248419.959711.4919
ENSG00000242875homo_sapiensENSP0000028172215.00947.50469homo_sapiensENSP0000037248416.1298.06452
ENSG00000242875homo_sapiensENSP0000035295612.98417.51708homo_sapiensENSP0000037248411.49196.65323
ENSG00000242875homo_sapiensENSP0000036293622.996513.5889homo_sapiensENSP0000037248413.30657.8629
ENSG00000242875homo_sapiensENSP0000031319926.478917.4648homo_sapiensENSP0000037248418.951612.5
ENSG00000242875homo_sapiensENSP0000025336311.69817.35849homo_sapiensENSP0000037248412.57.8629
ENSG00000242875homo_sapiensENSP0000036310913.31067.84983homo_sapiensENSP0000037248415.72589.27419
ENSG00000242875homo_sapiensENSP0000031604232.131120.6557homo_sapiensENSP0000037248419.758112.7016
ENSG00000242875homo_sapiensENSP0000031819512.11276.33803homo_sapiensENSP0000037248417.33879.07258
ENSG00000242875homo_sapiensENSP0000039490222.411.4667homo_sapiensENSP0000037248416.93558.66935
ENSG00000242875homo_sapiensENSP0000035110827.409617.4699homo_sapiensENSP0000037248418.346811.6935
ENSG00000242875homo_sapiensENSP000002617419.791674.58333homo_sapiensENSP0000037248418.95168.87097
ENSG00000242875homo_sapiensENSP0000023307831.449618.6732homo_sapiensENSP0000037248425.806515.3226
ENSG00000242875homo_sapiensENSP0000029547020.476212.381homo_sapiensENSP0000037248417.338710.4839
ENSG00000242875homo_sapiensENSP0000046602539.393928.6195homo_sapiensENSP0000037248423.588717.1371
ENSG00000242875homo_sapiensENSP0000036595064.331249.0446homo_sapiensENSP0000037248420.362915.5242
ENSG00000242875homo_sapiensENSP0000037210599.798499.5968homo_sapiensENSP0000037248499.798499.5968
ENSG00000242875homo_sapiensENSP0000037212799.798499.7984homo_sapiensENSP0000037248499.798499.7984
ENSG00000242875homo_sapiensENSP0000037215499.596899.5968homo_sapiensENSP0000037248499.596899.5968
ENSG00000242875homo_sapiensENSP0000030715599.193699.1936homo_sapiensENSP0000037248499.193699.1936
ENSG00000242875homo_sapiensENSP0000025083199.193699.1936homo_sapiensENSP0000037248499.193699.1936

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000242875homo_sapiensENSP0000037248493.145291.7339pan_troglodytesENSPTRP0000008674291.666790.2778
ENSG00000242875homo_sapiensENSP0000037248490.524288.7097pan_troglodytesENSPTRP0000008748991.260289.4309
ENSG00000242875homo_sapiensENSP0000037248495.161394.1532pan_troglodytesENSPTRP0000006512594.969893.9638
ENSG00000242875homo_sapiensENSP0000037248492.741991.9355pan_troglodytesENSPTRP0000006037194.262393.4426
ENSG00000242875homo_sapiensENSP0000037248492.943691.5323pan_troglodytesENSPTRP0000006320991.468390.0794
ENSG00000242875homo_sapiensENSP0000037248494.758193.75pan_troglodytesENSPTRP0000008668894.567493.5614
ENSG00000242875homo_sapiensENSP0000037248487.701686.6936pan_troglodytesENSPTRP0000006420793.548492.4731
ENSG00000242875homo_sapiensENSP0000037248492.943691.5323pan_troglodytesENSPTRP0000006298591.468390.0794
ENSG00000242875homo_sapiensENSP0000037248481.451676.2097pan_troglodytesENSPTRP0000006581986.140780.597
ENSG00000242875homo_sapiensENSP0000037248488.306487.0968pan_troglodytesENSPTRP0000008677592.016890.7563
ENSG00000242875homo_sapiensENSP0000037248494.959793.75pan_troglodytesENSPTRP0000007029794.388893.1864
ENSG00000242875homo_sapiensENSP0000037248483.87180.0403macaca_fascicularisENSMFAP0000006008970.270367.0608
ENSG00000242875homo_sapiensENSP0000037248484.072680.2419macaca_mulattaENSMMUP0000007558766.295763.275
ENSG00000242875homo_sapiensENSP0000037248437.534.4758macaca_mulattaENSMMUP0000004204380.519574.026
ENSG00000242875homo_sapiensENSP0000037248427.016123.9919marmota_marmota_marmotaENSMMMP0000000832081.212172.1212
ENSG00000242875homo_sapiensENSP0000037248442.943631.6532mus_musculusENSMUSP0000013952756.052641.3158
ENSG00000242875homo_sapiensENSP0000037248442.943631.6532mus_musculusENSMUSP0000014070456.052641.3158
ENSG00000242875homo_sapiensENSP0000037248442.943631.6532mus_musculusENSMUSP0000013978456.052641.3158
ENSG00000242875homo_sapiensENSP0000037248442.741931.6532mus_musculusENSMUSP0000014051255.789541.3158
ENSG00000242875homo_sapiensENSP0000037248422.580617.1371mus_musculusENSMUSP0000013996967.469951.2048
ENSG00000242875homo_sapiensENSP0000037248442.943631.8548mus_musculusENSMUSP0000014093656.052641.5789
ENSG00000242875homo_sapiensENSP0000037248442.943631.6532mus_musculusENSMUSP0000009793056.052641.3158
ENSG00000242875homo_sapiensENSP0000037248442.943631.8548mus_musculusENSMUSP0000014057556.052641.5789
ENSG00000242875homo_sapiensENSP0000037248442.943631.6532mus_musculusENSMUSP0000013965956.052641.3158
ENSG00000242875homo_sapiensENSP0000037248443.346832.2581mus_musculusENSMUSP0000014118356.578942.1053
ENSG00000242875homo_sapiensENSP0000037248471.774265.9274chlorocebus_sabaeusENSCSAP0000001431772.801666.8712
ENSG00000242875homo_sapiensENSP0000037248445.161334.2742rattus_norvegicusENSRNOP0000007464357.73243.8144
ENSG00000242875homo_sapiensENSP0000037248412.09689.27419mus_spicilegusENSMSIP000000055597557.5
ENSG00000242875homo_sapiensENSP0000037248470.564567.3387rhinopithecus_bietiENSRBIP0000000157082.938479.1469
ENSG00000242875homo_sapiensENSP0000037248427.016123.5887urocitellus_parryiiENSUPAP0001001114181.212170.9091
ENSG00000242875homo_sapiensENSP0000037248470.564567.7419rhinopithecus_roxellanaENSRROP0000001067183.135479.81
ENSG00000242875homo_sapiensENSP0000037248412.59.27419eptatretus_burgeriENSEBUP0000002406266.666749.4624
ENSG00000242875homo_sapiensENSP0000037248412.70169.67742eptatretus_burgeriENSEBUP0000001193367.021351.0638

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0003723enables RNA binding2IBA,NASHomo_sapiens(9606)Function
GO:0005634located_in nucleus1TASHomo_sapiens(9606)Component
GO:0005654located_in nucleoplasm1IDAHomo_sapiens(9606)Component
GO:0005681part_of spliceosomal complex1IBAHomo_sapiens(9606)Component
GO:0005730located_in nucleolus1IDAHomo_sapiens(9606)Component
GO:0006397involved_in mRNA processing1IEAHomo_sapiens(9606)Process
GO:0007283involved_in spermatogenesis1TASHomo_sapiens(9606)Process
GO:0008380involved_in RNA splicing1IEAHomo_sapiens(9606)Process
GO:0008584involved_in male gonad development1IMPHomo_sapiens(9606)Process
GO:0048026involved_in positive regulation of mRNA splicing, via spliceosome1IBAHomo_sapiens(9606)Process

Expression