Functions and Diseases

RBP Type Canonical_RBPs
Diseases N.A.
Drug N.A.
Main interacting RNAs mRNA
Moonlighting functions N.A.
Localizations Nucleoli
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000242389 Gene ID 378950 Accession 23916
Symbol RBMY1E Alias NA Full Name RNA binding motif protein Y-linked family 1 member E
Status Confidence Length 14425 bases Strand Minus strand
Position Y : 21903618 - 21918042 RNA binding domain RBM1CTR , RRM_1
Summary This gene encodes a protein containing an RNA-binding motif in the N-terminus and four SRGY (serine, arginine, glycine, tyrosine) boxes in the C-terminus. Multiple copies of this gene are found in the AZFb azoospermia factor region of chromosome Y and the encoded protein is thought to be involved in spermatogenesis. Most copies of this locus are pseudogenes, although six highly similar copies have full-length ORFs and are considered functional. Four functional copies of this gene are found within inverted repeat IR2; two functional copies of this gene are found in palindrome P3, along with two copies of PTPN13-like, Y-linked. [provided by RefSeq, Jul 2008]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000372104 RRM_1 PF00076 6.3e-21 1
ENSP00000372104 RBM1CTR PF08081 2.1e-21 2
ENSP00000372105 RRM_1 PF00076 7e-21 1
ENSP00000372105 RBM1CTR PF08081 2.3e-21 2
ENSP00000351823 RRM_1 PF00076 9.4e-21 1

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal

Transcripts

Name Transcript ID bp Protein Translation ID
RBMY1E-201 ENST00000358944 1718 81aa ENSP00000351823
RBMY1E-203 ENST00000382659 1882 496aa ENSP00000372105
RBMY1E-202 ENST00000382658 1773 459aa ENSP00000372104

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000242389homo_sapiensENSP0000029597112.98487.75717homo_sapiensENSP0000037210515.52429.27419
ENSG00000242389homo_sapiensENSP0000030413959.693948.2143homo_sapiensENSP0000037210547.177438.1048
ENSG00000242389homo_sapiensENSP0000041745118.837914.433homo_sapiensENSP0000037210540.524231.0484
ENSG00000242389homo_sapiensENSP0000047869134.604120.2346homo_sapiensENSP0000037210523.790313.9113
ENSG00000242389homo_sapiensENSP0000044536613.31447.64873homo_sapiensENSP000003721059.475815.44355
ENSG00000242389homo_sapiensENSP0000034182633.87119.6237homo_sapiensENSP0000037210525.403214.7177
ENSG00000242389homo_sapiensENSP0000035009037.187522.1875homo_sapiensENSP0000037210523.991914.3145
ENSG00000242389homo_sapiensENSP0000049380538.7522.8125homo_sapiensENSP000003721052514.7177
ENSG00000242389homo_sapiensENSP0000037630932.539720.1058homo_sapiensENSP0000037210524.798415.3226
ENSG00000242389homo_sapiensENSP0000028407329.573217.378homo_sapiensENSP0000037210519.556511.4919
ENSG00000242389homo_sapiensENSP0000031047121.72712.2563homo_sapiensENSP0000037210515.72588.87097
ENSG00000242389homo_sapiensENSP0000030916621.153811.8132homo_sapiensENSP0000037210515.52428.66935
ENSG00000242389homo_sapiensENSP0000049824871.538558.4615homo_sapiensENSP0000037210556.2545.9677
ENSG00000242389homo_sapiensENSP0000035964573.657360.8696homo_sapiensENSP0000037210558.064547.9839
ENSG00000242389homo_sapiensENSP0000040137122.020711.9171homo_sapiensENSP0000037210517.13719.27419
ENSG00000242389homo_sapiensENSP0000025755227.071815.4696homo_sapiensENSP0000037210519.758111.2903
ENSG00000242389homo_sapiensENSP0000028172214.82187.31707homo_sapiensENSP0000037210515.92747.8629
ENSG00000242389homo_sapiensENSP0000035295612.98417.51708homo_sapiensENSP0000037210511.49196.65323
ENSG00000242389homo_sapiensENSP0000036293622.648113.5889homo_sapiensENSP0000037210513.10487.8629
ENSG00000242389homo_sapiensENSP0000031319926.197217.1831homo_sapiensENSP0000037210518.7512.2984
ENSG00000242389homo_sapiensENSP0000025336311.50947.16981homo_sapiensENSP0000037210512.29847.66129
ENSG00000242389homo_sapiensENSP0000036310913.13997.67918homo_sapiensENSP0000037210515.52429.07258
ENSG00000242389homo_sapiensENSP0000031604232.131120.6557homo_sapiensENSP0000037210519.758112.7016
ENSG00000242389homo_sapiensENSP0000031819512.11276.33803homo_sapiensENSP0000037210517.33879.07258
ENSG00000242389homo_sapiensENSP0000039490222.411.4667homo_sapiensENSP0000037210516.93558.66935
ENSG00000242389homo_sapiensENSP0000035110827.108417.1687homo_sapiensENSP0000037210518.145211.4919
ENSG00000242389homo_sapiensENSP000002617419.68754.58333homo_sapiensENSP0000037210518.758.87097
ENSG00000242389homo_sapiensENSP0000023307831.203918.6732homo_sapiensENSP0000037210525.604815.3226
ENSG00000242389homo_sapiensENSP0000029547020.238112.1429homo_sapiensENSP0000037210517.137110.2823
ENSG00000242389homo_sapiensENSP0000046602539.057227.9461homo_sapiensENSP0000037210523.387116.7339
ENSG00000242389homo_sapiensENSP0000036595063.057348.4076homo_sapiensENSP0000037210519.959715.3226
ENSG00000242389homo_sapiensENSP0000037212710099.7984homo_sapiensENSP0000037210510099.7984
ENSG00000242389homo_sapiensENSP0000037248499.798499.5968homo_sapiensENSP0000037210599.798499.5968
ENSG00000242389homo_sapiensENSP0000037215499.798499.5968homo_sapiensENSP0000037210599.798499.5968
ENSG00000242389homo_sapiensENSP0000030715598.991998.7903homo_sapiensENSP0000037210598.991998.7903
ENSG00000242389homo_sapiensENSP0000025083198.991998.7903homo_sapiensENSP0000037210598.991998.7903

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000242389homo_sapiensENSP0000037210592.943691.3306pan_troglodytesENSPTRP0000008674291.468389.881
ENSG00000242389homo_sapiensENSP0000037210590.322688.3064pan_troglodytesENSPTRP0000008748991.056989.0244
ENSG00000242389homo_sapiensENSP0000037210594.959793.75pan_troglodytesENSPTRP0000006512594.768693.5614
ENSG00000242389homo_sapiensENSP0000037210592.540391.5323pan_troglodytesENSPTRP0000006037194.057493.0328
ENSG00000242389homo_sapiensENSP0000037210592.741991.129pan_troglodytesENSPTRP0000006320991.269889.6825
ENSG00000242389homo_sapiensENSP0000037210594.556493.3468pan_troglodytesENSPTRP0000008668894.366293.159
ENSG00000242389homo_sapiensENSP0000037210587.586.2903pan_troglodytesENSPTRP0000006420793.333392.043
ENSG00000242389homo_sapiensENSP0000037210592.741991.129pan_troglodytesENSPTRP0000006298591.269889.6825
ENSG00000242389homo_sapiensENSP0000037210581.2575.8064pan_troglodytesENSPTRP0000006581985.927580.1706
ENSG00000242389homo_sapiensENSP0000037210588.104886.6936pan_troglodytesENSPTRP0000008677591.806790.3361
ENSG00000242389homo_sapiensENSP0000037210594.758193.3468pan_troglodytesENSPTRP0000007029794.188492.7856
ENSG00000242389homo_sapiensENSP0000037210583.669479.6371macaca_fascicularisENSMFAP0000006008970.101366.723
ENSG00000242389homo_sapiensENSP0000037210583.87179.8387macaca_mulattaENSMMUP0000007558766.136762.9571
ENSG00000242389homo_sapiensENSP0000037210537.534.4758macaca_mulattaENSMMUP0000004204380.519574.026
ENSG00000242389homo_sapiensENSP0000037210527.016123.9919marmota_marmota_marmotaENSMMMP0000000832081.212172.1212
ENSG00000242389homo_sapiensENSP0000037210542.741931.4516mus_musculusENSMUSP0000013952755.789541.0526
ENSG00000242389homo_sapiensENSP0000037210542.741931.4516mus_musculusENSMUSP0000014070455.789541.0526
ENSG00000242389homo_sapiensENSP0000037210542.741931.4516mus_musculusENSMUSP0000013978455.789541.0526
ENSG00000242389homo_sapiensENSP0000037210542.540331.4516mus_musculusENSMUSP0000014051255.526341.0526
ENSG00000242389homo_sapiensENSP0000037210522.580617.1371mus_musculusENSMUSP0000013996967.469951.2048
ENSG00000242389homo_sapiensENSP0000037210542.741931.6532mus_musculusENSMUSP0000014093655.789541.3158
ENSG00000242389homo_sapiensENSP0000037210542.741931.4516mus_musculusENSMUSP0000009793055.789541.0526
ENSG00000242389homo_sapiensENSP0000037210542.741931.6532mus_musculusENSMUSP0000014057555.789541.3158
ENSG00000242389homo_sapiensENSP0000037210542.741931.4516mus_musculusENSMUSP0000013965955.789541.0526
ENSG00000242389homo_sapiensENSP0000037210543.145232.0564mus_musculusENSMUSP0000014118356.315841.8421
ENSG00000242389homo_sapiensENSP0000037210571.572665.5242chlorocebus_sabaeusENSCSAP0000001431772.597166.4622
ENSG00000242389homo_sapiensENSP0000037210544.959734.0726rattus_norvegicusENSRNOP0000007464357.474243.5567
ENSG00000242389homo_sapiensENSP0000037210512.09689.27419mus_spicilegusENSMSIP000000055597557.5
ENSG00000242389homo_sapiensENSP0000037210570.362966.9355rhinopithecus_bietiENSRBIP0000000157082.701478.673
ENSG00000242389homo_sapiensENSP0000037210527.016123.5887urocitellus_parryiiENSUPAP0001001114181.212170.9091
ENSG00000242389homo_sapiensENSP0000037210570.362967.3387rhinopithecus_roxellanaENSRROP0000001067182.897979.3349
ENSG00000242389homo_sapiensENSP0000037210512.59.27419eptatretus_burgeriENSEBUP0000002406266.666749.4624
ENSG00000242389homo_sapiensENSP0000037210512.70169.67742eptatretus_burgeriENSEBUP0000001193367.021351.0638

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0003723enables RNA binding1IBAHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005654located_in nucleoplasm1IDAHomo_sapiens(9606)Component
GO:0005681part_of spliceosomal complex1IBAHomo_sapiens(9606)Component
GO:0005730located_in nucleolus1IDAHomo_sapiens(9606)Component
GO:0006397involved_in mRNA processing1IEAHomo_sapiens(9606)Process
GO:0008380involved_in RNA splicing1IEAHomo_sapiens(9606)Process
GO:0048026involved_in positive regulation of mRNA splicing, via spliceosome1IBAHomo_sapiens(9606)Process

Expression