Functions and Diseases

RBP Type Canonical_RBPs
Diseases CancerSARS-COV-2Dengue
Drug Drug
Main interacting RNAs rRNA
Moonlighting functions Metabolic enzyme
Localizations N.A.
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000241343 Gene ID 6173 Accession 10359
Symbol RPL36A Alias L36A;L44L;MIG6;eL42;RPL44 Full Name ribosomal protein L36a
Status Confidence Length 5332 bases Strand Plus strand
Position X : 101390824 - 101396155 RNA binding domain Ribosomal_L44
Summary Cytoplasmic ribosomes, organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein, which shares sequence similarity with yeast ribosomal protein L44, belongs to the L44E (L36AE) family of ribosomal proteins. Although this gene has been referred to as ribosomal protein L44 (RPL44), its official name is ribosomal protein L36a (RPL36A). This gene and the human gene officially named ribosomal protein L36a-like (RPL36AL) encode nearly identical proteins; however, they are distinct genes. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Naturally occurring read-through transcription occurs between this locus and the heterogeneous nuclear ribonucleoprotein H2 (H') gene. [provided by RefSeq, Jan 2011]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000446503 Ribosomal_L44 PF00935 3.4e-34 1
ENSP00000397659 Ribosomal_L44 PF00935 4.1e-34 1
ENSP00000404375 Ribosomal_L44 PF00935 7.6e-34 1
ENSP00000483017 Ribosomal_L44 PF00935 7.6e-34 1
ENSP00000361940 Ribosomal_L44 PF00935 4.9e-17 1

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal

Transcripts

Name Transcript ID bp Protein Translation ID
RPL36A-203 ENST00000427805 910 142aa ENSP00000404375
RPL36A-210 ENST00000614077 881 142aa ENSP00000483017
RPL36A-202 ENST00000392994 691 112aa ENSP00000397659
RPL36A-208 ENST00000491851 547 No protein -
RPL36A-204 ENST00000465340 2240 No protein -
RPL36A-209 ENST00000553110 761 106aa ENSP00000446503
RPL36A-201 ENST00000372849 433 70aa ENSP00000361940
RPL36A-205 ENST00000465744 710 No protein -
RPL36A-206 ENST00000471855 399 25aa ENSP00000473451
RPL36A-207 ENST00000489407 373 No protein -

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000241343homo_sapiensENSP0000034601210099.0566homo_sapiensENSP0000044650310099.0566

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000241343homo_sapiensENSP00000446503100100pongo_abeliiENSPPYP0000002347074.647974.6479
ENSG00000241343homo_sapiensENSP00000446503100100gorilla_gorillaENSGGOP0000000924074.647974.6479
ENSG00000241343homo_sapiensENSP0000044650310099.0566sarcophilus_harrisiiENSSHAP0000002785348.847948.3871
ENSG00000241343homo_sapiensENSP00000446503100100choloepus_hoffmanniENSCHOP00000008466100100
ENSG00000241343homo_sapiensENSP00000446503100100callithrix_jacchusENSCJAP0000000886974.647974.6479
ENSG00000241343homo_sapiensENSP00000446503100100macaca_fascicularisENSMFAP0000003726174.647974.6479
ENSG00000241343homo_sapiensENSP0000044650392.452891.5094macaca_mulattaENSMMUP0000006208492.452891.5094
ENSG00000241343homo_sapiensENSP00000446503100100macaca_nemestrinaENSMNEP0000003672974.647974.6479
ENSG00000241343homo_sapiensENSP00000446503100100papio_anubisENSPANP0000000018974.647974.6479
ENSG00000241343homo_sapiensENSP0000044650397.169897.1698mandrillus_leucophaeusENSMLEP0000000357497.169897.1698
ENSG00000241343homo_sapiensENSP00000446503100100tursiops_truncatusENSTTRP00000007228100100
ENSG00000241343homo_sapiensENSP00000446503100100equus_asinusENSEASP0000504387470.198770.1987
ENSG00000241343homo_sapiensENSP00000446503100100capra_hircusENSCHIP0000003074774.647974.6479
ENSG00000241343homo_sapiensENSP00000446503100100loxodonta_africanaENSLAFP00000016108100100
ENSG00000241343homo_sapiensENSP00000446503100100panthera_leoENSPLOP0000002663274.647974.6479
ENSG00000241343homo_sapiensENSP0000044650399.056699.0566ailuropoda_melanoleucaENSAMEP0000000987874.468174.4681
ENSG00000241343homo_sapiensENSP00000446503100100oryctolagus_cuniculusENSOCUP00000025122100100
ENSG00000241343homo_sapiensENSP00000446503100100canis_lupus_familiarisENSCAFP0084500317235.333335.3333
ENSG00000241343homo_sapiensENSP00000446503100100marmota_marmota_marmotaENSMMMP00000017774100100
ENSG00000241343homo_sapiensENSP00000446503100100balaenoptera_musculusENSBMSP0001002789474.647974.6479
ENSG00000241343homo_sapiensENSP00000446503100100cavia_porcellusENSCPOP00000000484100100
ENSG00000241343homo_sapiensENSP00000446503100100felis_catusENSFCAP0000001427774.647974.6479
ENSG00000241343homo_sapiensENSP00000446503100100ursus_americanusENSUAMP0000000384582.812582.8125
ENSG00000241343homo_sapiensENSP00000446503100100monodon_monocerosENSMMNP0001501744180.30380.303
ENSG00000241343homo_sapiensENSP00000446503100100sus_scrofaENSSSCP0000000538535.451535.4515
ENSG00000241343homo_sapiensENSP00000446503100100microcebus_murinusENSMICP00000048240100100
ENSG00000241343homo_sapiensENSP0000044650399.056699.0566microcebus_murinusENSMICP0000004661299.056699.0566
ENSG00000241343homo_sapiensENSP00000446503100100ovis_aries_rambouilletENSOARP0002002199474.647974.6479
ENSG00000241343homo_sapiensENSP00000446503100100ursus_maritimusENSUMAP0000001651574.647974.6479
ENSG00000241343homo_sapiensENSP00000446503100100physeter_catodonENSPCTP0000500909674.647974.6479
ENSG00000241343homo_sapiensENSP00000446503100100mus_musculusENSMUSP00000106249100100
ENSG00000241343homo_sapiensENSP00000446503100100chlorocebus_sabaeusENSCSAP0000000610474.647974.6479
ENSG00000241343homo_sapiensENSP0000044650398.113298.1132mesocricetus_auratusENSMAUP0000000342698.113298.1132
ENSG00000241343homo_sapiensENSP00000446503100100mesocricetus_auratusENSMAUP00000017180100100
ENSG00000241343homo_sapiensENSP00000446503100100phocoena_sinusENSPSNP0000002753674.647974.6479
ENSG00000241343homo_sapiensENSP0000044650397.169896.2264camelus_dromedariusENSCDRP0000501910566.883166.2338
ENSG00000241343homo_sapiensENSP00000446503100100carlito_syrichtaENSTSYP0000002194874.647974.6479
ENSG00000241343homo_sapiensENSP00000446503100100rattus_norvegicusENSRNOP00000048003100100
ENSG00000241343homo_sapiensENSP00000446503100100prolemur_simusENSPSMP00000002605100100
ENSG00000241343homo_sapiensENSP00000446503100100microtus_ochrogasterENSMOCP00000003099100100
ENSG00000241343homo_sapiensENSP0000044650399.056696.2264sorex_araneusENSSARP0000000195299.056696.2264
ENSG00000241343homo_sapiensENSP00000446503100100cricetulus_griseus_chok1gshdENSCGRP00001023317100100
ENSG00000241343homo_sapiensENSP00000446503100100pteropus_vampyrusENSPVAP00000001478100100
ENSG00000241343homo_sapiensENSP0000044650397.169894.3396myotis_lucifugusENSMLUP0000001263897.169894.3396
ENSG00000241343homo_sapiensENSP0000044650310099.0566neovison_visonENSNVIP0000000977810099.0566
ENSG00000241343homo_sapiensENSP00000446503100100bos_taurusENSBTAP00000020267100100
ENSG00000241343homo_sapiensENSP00000446503100100heterocephalus_glaber_femaleENSHGLP0000004636773.611173.6111
ENSG00000241343homo_sapiensENSP00000446503100100rhinopithecus_bietiENSRBIP00000012464100100
ENSG00000241343homo_sapiensENSP00000446503100100canis_lupus_dingoENSCAFP0002000912074.647974.6479
ENSG00000241343homo_sapiensENSP00000446503100100sciurus_vulgarisENSSVLP0000502275174.647974.6479
ENSG00000241343homo_sapiensENSP00000446503100100nannospalax_galiliENSNGAP00000023330100100
ENSG00000241343homo_sapiensENSP00000446503100100nannospalax_galiliENSNGAP00000011258100100
ENSG00000241343homo_sapiensENSP00000446503100100bos_grunniensENSBGRP0000003154974.647974.6479
ENSG00000241343homo_sapiensENSP00000446503100100chinchilla_lanigeraENSCLAP00000020197100100
ENSG00000241343homo_sapiensENSP00000446503100100cervus_hanglu_yarkandensisENSCHYP00000007866100100
ENSG00000241343homo_sapiensENSP00000446503100100ictidomys_tridecemlineatusENSSTOP00000030727100100
ENSG00000241343homo_sapiensENSP00000446503100100otolemur_garnettiiENSOGAP0000001184994.642994.6429
ENSG00000241343homo_sapiensENSP00000446503100100cebus_imitatorENSCCAP0000000328274.647974.6479
ENSG00000241343homo_sapiensENSP00000446503100100urocitellus_parryiiENSUPAP00010012483100100
ENSG00000241343homo_sapiensENSP00000446503100100rhinopithecus_roxellanaENSRROP00000003448100100
ENSG00000241343homo_sapiensENSP00000446503100100rhinopithecus_roxellanaENSRROP00000001506100100
ENSG00000241343homo_sapiensENSP00000446503100100mus_pahariMGP_PahariEiJ_P0082509100100
ENSG00000241343homo_sapiensENSP00000446503100100propithecus_coquereliENSPCOP00000016777100100
ENSG00000241343homo_sapiensENSP0000044650396.226491.5094callorhinchus_miliiENSCMIP0000000426467.549764.2384
ENSG00000241343homo_sapiensENSP0000044650352.830245.283astyanax_mexicanusENSAMXP000000278808068.5714
ENSG00000241343homo_sapiensENSP0000044650395.28392.4528poecilia_reticulataENSPREP0000001872571.126869.0141
ENSG00000241343homo_sapiensENSP0000044650399.056699.0566oryzias_latipesENSORLP0000003074161.403561.4035
ENSG00000241343homo_sapiensENSP0000044650399.056696.2264xenopus_tropicalisENSXETP0000011124699.056696.2264
ENSG00000241343homo_sapiensENSP0000044650399.056696.2264sphenodon_punctatusENSSPUP0000002277410097.1429
ENSG00000241343homo_sapiensENSP0000044650396.226494.3396crocodylus_porosusENSCPRP0000501347797.142995.2381
ENSG00000241343homo_sapiensENSP0000044650353.773647.1698anolis_carolinensisENSACAP0000002422668.674760.241
ENSG00000241343homo_sapiensENSP0000044650382.075579.2453podarcis_muralisENSPMRP0000001765453.374251.5337
ENSG00000241343homo_sapiensENSP0000044650399.056698.1132geospiza_fortisENSGFOP0000000338410099.0476
ENSG00000241343homo_sapiensENSP0000044650395.28392.4528erpetoichthys_calabaricusENSECRP0000001966375.939873.6842
ENSG00000241343homo_sapiensENSP0000044650397.169894.3396salvator_merianaeENSSMRP0000001692376.296374.0741
ENSG00000241343homo_sapiensENSP0000044650398.113296.2264amphiprion_perculaENSAPEP0000000682698.113296.2264
ENSG00000241343homo_sapiensENSP0000044650395.28394.3396seriola_dumeriliENSSDUP0000000675269.178168.4931
ENSG00000241343homo_sapiensENSP0000044650399.056698.1132anser_brachyrhynchusENSABRP0000000076110099.0476
ENSG00000241343homo_sapiensENSP0000044650397.169895.283amphiprion_ocellarisENSAOCP0000001545488.793187.069
ENSG00000241343homo_sapiensENSP0000044650398.113295.283betta_splendensENSBSLP0000005384063.414661.5854
ENSG00000241343homo_sapiensENSP0000044650363.207558.4906labrus_bergyltaENSLBEP0000000528049.629645.9259
ENSG00000241343homo_sapiensENSP0000044650398.113297.1698stegastes_partitusENSSPAP0000001375567.096866.4516
ENSG00000241343homo_sapiensENSP0000044650397.169894.3396denticeps_clupeoidesENSDCDP0000002637828.374727.5482
ENSG00000241343homo_sapiensENSP0000044650398.113296.2264hippocampus_comesENSHCOP0000002119198.113296.2264
ENSG00000241343homo_sapiensENSP0000044650396.226492.4528cyprinus_carpio_carpioENSCCRP0000015273459.649157.3099
ENSG00000241343homo_sapiensENSP0000044650396.226491.5094leptobrachium_leishanenseENSLLEP0000002770377.272773.4848

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0002181involved_in cytoplasmic translation2IC,IDAHomo_sapiens(9606)Process
GO:0003723enables RNA binding1HDAHomo_sapiens(9606)Function
GO:0003735enables structural constituent of ribosome3IC,IDA,NASHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005783located_in endoplasmic reticulum1IDAHomo_sapiens(9606)Component
GO:0005829located_in cytosol2IDA,TASHomo_sapiens(9606)Component
GO:0005840located_in ribosome1NASHomo_sapiens(9606)Component
GO:0005886located_in plasma membrane1IDAHomo_sapiens(9606)Component
GO:0006412involved_in translation1NASHomo_sapiens(9606)Process
GO:0022625part_of cytosolic large ribosomal subunit3HDA,IBA,IDAHomo_sapiens(9606)Component
GO:0022626located_in cytosolic ribosome1IDAHomo_sapiens(9606)Component
GO:0042788located_in polysomal ribosome1IDAHomo_sapiens(9606)Component

Expression