RBPWorld - a comprehensive database of RNA Binding Proteins

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RBP World!

Functions and Diseases

RBP Type	Non-canonical_RBPs
Diseases	N.A.
Drug	N.A.
Main interacting RNAs	N.A.
Moonlighting functions	TF
Localizations	Nucleoli
BulkPerturb-seq

Description

Ensembl ID	ENSG00000234616	Gene ID	8629	Accession	6199
Symbol	JRK	Alias	JH8;jerky	Full Name	Jrk helix-turn-helix protein
Status	Confidence	Length	12535 bases	Strand	Minus strand
Position	8 : 142657460 - 142669994	RNA binding domain	N.A.
Summary	This gene encodes a conserved protein that is similar to DNA-binding proteins, such as major centromere autoantigen B (CENPB). Inactivation of the related gene in mice resulted in epileptic seizures. Childhood Absence Epilepsy (CAE) has been mapped to the same chromosomal location (8q24.3) as this gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

RNA binding domains (RBDs)

Protein	Domain	Pfam ID	E-value	Domain number

RNA binding proteomes (RBPomes)

Pubmed ID	Full Name	Cell	Author	Time	Doi

Literatures on RNA binding capacity

Pubmed ID	Title	Author	Time	Journal

Transcripts

Name	Transcript ID	bp	Protein	Translation ID
JRK-210	ENST00000614134	8932	568aa	ENSP00000485390
JRK-209	ENST00000612905	9097	568aa	ENSP00000482410
JRK-211	ENST00000615982	2823	556aa	ENSP00000483808
JRK-203	ENST00000571961	2687	556aa	ENSP00000461610
JRK-202	ENST00000506774	561	No protein	-
JRK-201	ENST00000503272	587	25aa	ENSP00000482585
JRK-208	ENST00000591357	571	No protein	-
JRK-207	ENST00000591180	669	No protein	-
JRK-206	ENST00000587883	574	No protein	-
JRK-204	ENST00000585503	1175	No protein	-
JRK-205	ENST00000587499	1092	No protein	-

Gene Model

Click here to download ENSG00000234616's gene model file

Pathways

Pathway ID	Pathway Name	Source

Phenotypes

ensgID	Trait	pValue	Pubmed ID

GWAS

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Protein-Protein Interaction (PPI)

Click here to download ENSG00000234616's PPI file

Paralogs

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Orthologs

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Gene Ontology

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0003677	enables DNA binding	1	IBA	Homo_sapiens(9606)	Function
GO:0003729	enables mRNA binding	1	IEA	Homo_sapiens(9606)	Function
GO:0005515	enables protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0005575	is_active_in cellular_component	1	ND	Homo_sapiens(9606)	Component
GO:0005634	is_active_in nucleus	1	IBA	Homo_sapiens(9606)	Component
GO:0005737	located_in cytoplasm	1	IEA	Homo_sapiens(9606)	Component
GO:0090263	involved_in positive regulation of canonical Wnt signaling pathway	1	IMP	Homo_sapiens(9606)	Process
GO:1990904	part_of ribonucleoprotein complex	1	IEA	Homo_sapiens(9606)	Component

Expression