Functions and Diseases

RBP Type Canonical_RBPs
Diseases N.A.
Drug N.A.
Main interacting RNAs mRNA
Moonlighting functions N.A.
Localizations Nucleoli
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000226941 Gene ID 378951 Accession 23917
Symbol RBMY1J Alias NA Full Name RNA binding motif protein Y-linked family 1 member J
Status Confidence Length 14472 bases Strand Plus strand
Position Y : 22403410 - 22417881 RNA binding domain RBM1CTR , RRM_1
Summary This gene encodes a protein containing an RNA-binding motif in the N-terminus and four SRGY (serine, arginine, glycine, tyrosine) boxes in the C-terminus. This protein likely functions as a splicing factor during spermatogenesis. Multiple closely related paralogs of this gene are found in a gene cluster in the AZFb azoospermia factor region of chromosome Y. Most of these related copies are thought to be pseudogenes, though several likely encode functional proteins. [provided by RefSeq, Mar 2016]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000250831 RRM_1 PF00076 1.2e-20 1
ENSP00000250831 RBM1CTR PF08081 2.3e-21 2

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
31134133 Identifying Novel Copy Number Variants in Azoospermia Factor Regions and Evaluating Their Effects on Spermatogenic Impairment. Ran Zhou 2019-01-01 Frontiers in genetics

Transcripts

Name Transcript ID bp Protein Translation ID
RBMY1J-202 ENST00000470460 1717 No protein -
RBMY1J-201 ENST00000250831 1946 496aa ENSP00000250831

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000226941homo_sapiensENSP0000029597112.98487.75717homo_sapiensENSP0000025083115.52429.27419
ENSG00000226941homo_sapiensENSP0000030413959.438848.2143homo_sapiensENSP0000025083146.975838.1048
ENSG00000226941homo_sapiensENSP0000041745118.744114.3393homo_sapiensENSP0000025083140.322630.8468
ENSG00000226941homo_sapiensENSP0000047869134.310920.5279homo_sapiensENSP0000025083123.588714.1129
ENSG00000226941homo_sapiensENSP0000044536613.59777.93201homo_sapiensENSP000002508319.677425.64516
ENSG00000226941homo_sapiensENSP0000034182633.602119.8925homo_sapiensENSP0000025083125.201614.9194
ENSG00000226941homo_sapiensENSP0000035009037.522.8125homo_sapiensENSP0000025083124.193514.7177
ENSG00000226941homo_sapiensENSP0000049380538.437523.125homo_sapiensENSP0000025083124.798414.9194
ENSG00000226941homo_sapiensENSP0000037630932.275120.3704homo_sapiensENSP0000025083124.596815.5242
ENSG00000226941homo_sapiensENSP0000028407330.182917.9878homo_sapiensENSP0000025083119.959711.8952
ENSG00000226941homo_sapiensENSP0000031047122.284112.8134homo_sapiensENSP0000025083116.1299.27419
ENSG00000226941homo_sapiensENSP0000030916621.703312.3626homo_sapiensENSP0000025083115.92749.07258
ENSG00000226941homo_sapiensENSP0000049824871.538558.9744homo_sapiensENSP0000025083156.2546.371
ENSG00000226941homo_sapiensENSP0000035964573.657361.3811homo_sapiensENSP0000025083158.064548.3871
ENSG00000226941homo_sapiensENSP0000040137122.279812.1762homo_sapiensENSP0000025083117.33879.47581
ENSG00000226941homo_sapiensENSP0000025755227.900616.0221homo_sapiensENSP0000025083120.362911.6935
ENSG00000226941homo_sapiensENSP0000028172215.00947.50469homo_sapiensENSP0000025083116.1298.06452
ENSG00000226941homo_sapiensENSP0000035295612.75637.51708homo_sapiensENSP0000025083111.29036.65323
ENSG00000226941homo_sapiensENSP0000036293623.344913.5889homo_sapiensENSP0000025083113.50817.8629
ENSG00000226941homo_sapiensENSP0000031319926.478917.4648homo_sapiensENSP0000025083118.951612.5
ENSG00000226941homo_sapiensENSP0000025336311.88687.35849homo_sapiensENSP0000025083112.70167.8629
ENSG00000226941homo_sapiensENSP0000036310913.31067.84983homo_sapiensENSP0000025083115.72589.27419
ENSG00000226941homo_sapiensENSP0000031604232.131120.6557homo_sapiensENSP0000025083119.758112.7016
ENSG00000226941homo_sapiensENSP0000031819512.25356.47887homo_sapiensENSP0000025083117.54039.27419
ENSG00000226941homo_sapiensENSP0000039490222.666711.7333homo_sapiensENSP0000025083117.13718.87097
ENSG00000226941homo_sapiensENSP0000035110827.409617.1687homo_sapiensENSP0000025083118.346811.4919
ENSG00000226941homo_sapiensENSP000002617419.791674.58333homo_sapiensENSP0000025083118.95168.87097
ENSG00000226941homo_sapiensENSP0000023307831.203918.9189homo_sapiensENSP0000025083125.604815.5242
ENSG00000226941homo_sapiensENSP0000029547020.476212.381homo_sapiensENSP0000025083117.338710.4839
ENSG00000226941homo_sapiensENSP0000046602539.393928.2828homo_sapiensENSP0000025083123.588716.9355
ENSG00000226941homo_sapiensENSP0000036595063.694349.0446homo_sapiensENSP0000025083120.161315.5242
ENSG00000226941homo_sapiensENSP00000307155100100homo_sapiensENSP00000250831100100
ENSG00000226941homo_sapiensENSP0000037210598.991998.7903homo_sapiensENSP0000025083198.991998.7903
ENSG00000226941homo_sapiensENSP0000037215499.193699.1936homo_sapiensENSP0000025083199.193699.1936
ENSG00000226941homo_sapiensENSP0000037212798.991998.9919homo_sapiensENSP0000025083198.991998.9919
ENSG00000226941homo_sapiensENSP0000037248499.193699.1936homo_sapiensENSP0000025083199.193699.1936

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000226941homo_sapiensENSP0000025083193.548492.1371pan_troglodytesENSPTRP0000008674292.063590.6746
ENSG00000226941homo_sapiensENSP0000025083190.927489.1129pan_troglodytesENSPTRP0000008748991.666789.8374
ENSG00000226941homo_sapiensENSP0000025083195.564594.5564pan_troglodytesENSPTRP0000006512595.372294.3662
ENSG00000226941homo_sapiensENSP0000025083192.943692.1371pan_troglodytesENSPTRP0000006037194.467293.6475
ENSG00000226941homo_sapiensENSP0000025083193.346891.9355pan_troglodytesENSPTRP0000006320991.865190.4762
ENSG00000226941homo_sapiensENSP0000025083195.161394.1532pan_troglodytesENSPTRP0000008668894.969893.9638
ENSG00000226941homo_sapiensENSP0000025083188.104887.0968pan_troglodytesENSPTRP0000006420793.978592.9032
ENSG00000226941homo_sapiensENSP0000025083193.346891.9355pan_troglodytesENSPTRP0000006298591.865190.4762
ENSG00000226941homo_sapiensENSP0000025083181.854876.6129pan_troglodytesENSPTRP0000006581986.567281.0235
ENSG00000226941homo_sapiensENSP0000025083188.508187.2984pan_troglodytesENSPTRP0000008677592.226990.9664
ENSG00000226941homo_sapiensENSP0000025083195.362994.1532pan_troglodytesENSPTRP0000007029794.789693.5872
ENSG00000226941homo_sapiensENSP0000025083184.274280.4436macaca_fascicularisENSMFAP0000006008970.608167.3987
ENSG00000226941homo_sapiensENSP0000025083184.475880.6452macaca_mulattaENSMMUP0000007558766.613763.593
ENSG00000226941homo_sapiensENSP0000025083137.701634.6774macaca_mulattaENSMMUP0000004204380.952474.4589
ENSG00000226941homo_sapiensENSP0000025083126.814523.9919marmota_marmota_marmotaENSMMMP0000000832080.606172.1212
ENSG00000226941homo_sapiensENSP0000025083142.741931.4516mus_musculusENSMUSP0000013952755.789541.0526
ENSG00000226941homo_sapiensENSP0000025083142.741931.4516mus_musculusENSMUSP0000014070455.789541.0526
ENSG00000226941homo_sapiensENSP0000025083142.741931.4516mus_musculusENSMUSP0000013978455.789541.0526
ENSG00000226941homo_sapiensENSP0000025083142.540331.4516mus_musculusENSMUSP0000014051255.526341.0526
ENSG00000226941homo_sapiensENSP0000025083122.37916.9355mus_musculusENSMUSP0000013996966.867550.6024
ENSG00000226941homo_sapiensENSP0000025083142.741931.6532mus_musculusENSMUSP0000014093655.789541.3158
ENSG00000226941homo_sapiensENSP0000025083142.741931.4516mus_musculusENSMUSP0000009793055.789541.0526
ENSG00000226941homo_sapiensENSP0000025083142.741931.6532mus_musculusENSMUSP0000014057555.789541.3158
ENSG00000226941homo_sapiensENSP0000025083142.741931.4516mus_musculusENSMUSP0000013965955.789541.0526
ENSG00000226941homo_sapiensENSP0000025083143.145232.0564mus_musculusENSMUSP0000014118356.315841.8421
ENSG00000226941homo_sapiensENSP0000025083171.975866.129chlorocebus_sabaeusENSCSAP0000001431773.006167.0757
ENSG00000226941homo_sapiensENSP0000025083145.161334.4758rattus_norvegicusENSRNOP0000007464357.73244.0722
ENSG00000226941homo_sapiensENSP0000025083112.09689.27419mus_spicilegusENSMSIP000000055597557.5
ENSG00000226941homo_sapiensENSP0000025083170.766167.5403rhinopithecus_bietiENSRBIP0000000157083.175479.3839
ENSG00000226941homo_sapiensENSP0000025083126.814523.5887urocitellus_parryiiENSUPAP0001001114180.606170.9091
ENSG00000226941homo_sapiensENSP0000025083170.766167.9436rhinopithecus_roxellanaENSRROP0000001067183.372980.0475
ENSG00000226941homo_sapiensENSP0000025083112.29849.07258eptatretus_burgeriENSEBUP0000002406265.591448.3871
ENSG00000226941homo_sapiensENSP0000025083112.70169.47581eptatretus_burgeriENSEBUP0000001193367.021350

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0003723enables RNA binding1IBAHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005654located_in nucleoplasm1IDAHomo_sapiens(9606)Component
GO:0005681part_of spliceosomal complex1IBAHomo_sapiens(9606)Component
GO:0005730located_in nucleolus1IDAHomo_sapiens(9606)Component
GO:0006397involved_in mRNA processing1IEAHomo_sapiens(9606)Process
GO:0008380involved_in RNA splicing1IEAHomo_sapiens(9606)Process
GO:0042802enables identical protein binding1IPIHomo_sapiens(9606)Function
GO:0048026involved_in positive regulation of mRNA splicing, via spliceosome1IBAHomo_sapiens(9606)Process

Expression