Functions and Diseases

RBP Type Canonical_RBPs
Diseases N.A.
Drug N.A.
Main interacting RNAs N.A.
Moonlighting functions E3 ligase
Localizations N.A.
BulkPerturb-seq

Description

Ensembl ID ENSG00000223638 Gene ID 342931 Accession 16449
Symbol RFPL4A Alias RFPL4;RNF210 Full Name ret finger protein like 4A
Status Confidence Length 4325 bases Strand Plus strand
Position 19 : 55759097 - 55763421 RNA binding domain SPRY
Summary Predicted to enable ubiquitin-protein transferase activity. Predicted to be involved in positive regulation of transcription, DNA-templated. Predicted to be located in nucleus. Predicted to be active in chromatin and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000392936 SPRY PF00622 1.9e-12 1

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal

Transcripts

Name Transcript ID bp Protein Translation ID
RFPL4A-201 ENST00000434937 1198 287aa ENSP00000392936

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0000209involved_in protein polyubiquitination1IBAHomo_sapiens(9606)Process
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005654is_active_in nucleoplasm1IBAHomo_sapiens(9606)Component
GO:0005737is_active_in cytoplasm1IBAHomo_sapiens(9606)Component
GO:0005829is_active_in cytosol1IBAHomo_sapiens(9606)Component
GO:0010508involved_in positive regulation of autophagy1IBAHomo_sapiens(9606)Process
GO:0019901enables protein kinase binding1IBAHomo_sapiens(9606)Function
GO:0032880involved_in regulation of protein localization1IBAHomo_sapiens(9606)Process
GO:0042803enables protein homodimerization activity1IBAHomo_sapiens(9606)Function
GO:0043123involved_in positive regulation of I-kappaB kinase/NF-kappaB signaling1IBAHomo_sapiens(9606)Process
GO:0045087involved_in innate immune response1IBAHomo_sapiens(9606)Process
GO:0046596involved_in regulation of viral entry into host cell1IBAHomo_sapiens(9606)Process
GO:0046872enables metal ion binding1IEAHomo_sapiens(9606)Function
GO:0051092involved_in positive regulation of NF-kappaB transcription factor activity1IBAHomo_sapiens(9606)Process
GO:0061630enables ubiquitin protein ligase activity1IBAHomo_sapiens(9606)Function

Expression