Functions and Diseases

RBP Type Non-canonical_RBPs
Diseases CancerFlavivirusesSARS-COV-2DengueZika
Drug N.A.
Main interacting RNAs ncRNA
Moonlighting functions E3 ligase
Localizations Stress granucle
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000206557 Gene ID 131405 Accession 32669
Symbol TRIM71 Alias HYC4;LIN41;HYDCC1;LIN-41 Full Name tripartite motif containing 71
Status Confidence Length 79828 bases Strand Plus strand
Position 3 : 32817997 - 32897824 RNA binding domain N.A.
Summary The protein encoded by this gene is an E3 ubiquitin-protein ligase that binds with miRNAs and maintains the growth and upkeep of embryonic stem cells. This gene also is involved in the G1-S phase transition of the cell cycle. [provided by RefSeq, Dec 2015]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
32738036 Molecular and biological functions of TRIM-NHL RNA-binding proteins. P Robert Connacher 2021-03-01 Wiley interdisciplinary reviews. RNA
36757932 Different congenital hydrocephalus-associated mutations in Trim71 impair stem cell differentiation via distinct gain-of-function mechanisms. Qiuying Liu 2023-02-01 PLoS biology
33077954 Exome sequencing implicates genetic disruption of prenatal neuro-gliogenesis in sporadic congenital hydrocephalus. Chih Sheng Jin 2020-11-01 Nature medicine
37559904 The cytoplasmic fraction of the histone lysine methyltransferase Setdb1 is essential for embryonic stem cells. Roberta Rapone 2023-08-18 iScience
23125361 The mammalian TRIM-NHL protein TRIM71/LIN-41 is a repressor of mRNA function. Inga Loedige 2013-01-07 Nucleic acids research
31371437 The RNA hairpin binder TRIM71 modulates alternative splicing by repressing MBNL1. Thomas Welte 2019-09-01 Genes & development
26871474 MALAT1 long ncRNA promotes gastric cancer metastasis by suppressing PCDH10. Ying Qi 2016-03-15 Oncotarget
32816599 TRIM71 binds to IMP1 and is capable of positive and negative regulation of target RNAs. J Daniel Foster 2020-09-01 Cell cycle (Georgetown, Tex.)
34990576 Brain ventricles as windows into brain development and disease. Q Phan Duy 2022-01-05 Neuron
31732746 The mRNA repressor TRIM71 cooperates with Nonsense-Mediated Decay factors to destabilize the mRNA of CDKN1A/p21. A Lucia Torres-Fernández 2019-12-16 Nucleic acids research
33975917 The stem cell-specific protein TRIM71 inhibits maturation and activity of the pro-differentiation miRNA let-7 via two independent molecular mechanisms. A Lucia LA Torres 2021-05-11 RNA (New York, N.Y.)
25115389 Identification of a gene expression driven progression pathway in myxoid liposarcoma. Loris L De 2014-08-15 Oncotarget
29117863 RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination. Roy Nila Choudhury 2017-11-08 BMC biology
27821801 TRIM71 suppresses tumorigenesis via modulation of Lin28B-let-7-HMGA2 signaling. Jinlong Yin 2016-11-29 Oncotarget
37369201 Convergence of multiple RNA-silencing pathways on GW182/TNRC6. Thomas Welte 2023-07-20 Molecular cell
36757939 Gain-of-function mutations in Trim71 linked to congenital hydrocephalus. Yingying Chen 2023-02-01 PLoS biology
33599613 Repressing Ago2 mRNA translation by Trim71 maintains pluripotency through inhibiting let-7 microRNAs. Qiuying Liu 2021-02-18 eLife
35379995 Impaired neurogenesis alters brain biomechanics in a neuroprogenitor-based genetic subtype of congenital hydrocephalus. Q Phan Duy 2022-04-01 Nature neuroscience
24696456 The NHL domain of BRAT is an RNA-binding domain that directly contacts the hunchback mRNA for regulation. Inga Loedige 2014-04-01 Genes & development
33482040 Targeting TRIM Proteins: A Quest towards Drugging an Emerging Protein Class. Francesca D'Amico 2021-06-15 Chembiochem : a European journal of chemical biology
30911006 A TRIM71 binding long noncoding RNA Trincr1 represses FGF/ERK signaling in embryonic stem cells. Ya-Pu Li 2019-03-25 Nature communications

Transcripts

Name Transcript ID bp Protein Translation ID
TRIM71-201 ENST00000383763 8704 868aa ENSP00000373272

Gene Model

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
62958Forced Expiratory Volume4E-621946350
62959Respiratory Function Tests4E-621946350
91615Venous Thromboembolism1E-923509962

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000206557homo_sapiensENSP0000036640428.265115.3996homo_sapiensENSP0000037327216.70519.10138
ENSG00000206557homo_sapiensENSP0000025664923.103412.7586homo_sapiensENSP0000037327215.43788.52535
ENSG00000206557homo_sapiensENSP0000025481623.354213.0094homo_sapiensENSP0000037327217.16599.56221
ENSG00000206557homo_sapiensENSP0000049630120.508210.1633homo_sapiensENSP0000037327213.01846.45161
ENSG00000206557homo_sapiensENSP0000051816427.176212.9512homo_sapiensENSP0000037327214.74657.02765
ENSG00000206557homo_sapiensENSP0000042114228.025513.8004homo_sapiensENSP0000037327215.20747.48848
ENSG00000206557homo_sapiensENSP0000042393422.48610.7542homo_sapiensENSP0000037327218.54848.87097
ENSG00000206557homo_sapiensENSP0000036588427.096815.914homo_sapiensENSP0000037327214.51618.52535
ENSG00000206557homo_sapiensENSP0000035125012.95476.65484homo_sapiensENSP0000037327216.82038.64055
ENSG00000206557homo_sapiensENSP0000026229417.01247.98755homo_sapiensENSP0000037327218.8948.87097
ENSG00000206557homo_sapiensENSP0000032799425.051313.5524homo_sapiensENSP0000037327214.05537.60369
ENSG00000206557homo_sapiensENSP0000025443634.315816.8421homo_sapiensENSP0000037327218.77889.21659
ENSG00000206557homo_sapiensENSP0000034312920.0689.01361homo_sapiensENSP0000037327213.59456.10599
ENSG00000206557homo_sapiensENSP0000050713114.33967.2956homo_sapiensENSP0000037327213.13366.68203
ENSG00000206557homo_sapiensENSP0000035561313.66546.76884homo_sapiensENSP0000037327212.32726.10599
ENSG00000206557homo_sapiensENSP000004746782511.9469homo_sapiensENSP0000037327213.01846.2212
ENSG00000206557homo_sapiensENSP000004850972511.9469homo_sapiensENSP0000037327213.01846.2212
ENSG00000206557homo_sapiensENSP0000040241425.892914.2857homo_sapiensENSP000003732726.682033.68664
ENSG00000206557homo_sapiensENSP0000029141631.157916.8421homo_sapiensENSP0000037327217.05079.21659
ENSG00000206557homo_sapiensENSP0000036937326.774814.8073homo_sapiensENSP0000037327215.20748.41014
ENSG00000206557homo_sapiensENSP0000026805815.64637.82313homo_sapiensENSP0000037327215.89867.94931
ENSG00000206557homo_sapiensENSP0000031861524.814.8homo_sapiensENSP000003732727.142864.26267
ENSG00000206557homo_sapiensENSP0000028580524.814.8homo_sapiensENSP000003732727.142864.26267
ENSG00000206557homo_sapiensENSP0000047400326.666714.2222homo_sapiensENSP0000037327213.82497.37327
ENSG00000206557homo_sapiensENSP0000030516117.61599.93377homo_sapiensENSP0000037327215.32268.64055
ENSG00000206557homo_sapiensENSP0000031267525.995814.4654homo_sapiensENSP0000037327214.28577.94931
ENSG00000206557homo_sapiensENSP0000029941317.15129.01163homo_sapiensENSP000003732726.797243.57143
ENSG00000206557homo_sapiensENSP0000034959633.978516.5591homo_sapiensENSP0000037327218.20288.87097
ENSG00000206557homo_sapiensENSP0000028455131.837616.6667homo_sapiensENSP0000037327217.16598.98618
ENSG00000206557homo_sapiensENSP0000036742426.535612.7764homo_sapiensENSP0000037327212.44245.99078
ENSG00000206557homo_sapiensENSP0000040259526.844314.959homo_sapiensENSP0000037327215.09228.41014
ENSG00000206557homo_sapiensENSP0000049541310.12934.09483homo_sapiensENSP0000037327216.24426.56682
ENSG00000206557homo_sapiensENSP0000034079749.059134.4086homo_sapiensENSP0000037327242.050729.4931
ENSG00000206557homo_sapiensENSP0000032388919.365111.1111homo_sapiensENSP0000037327214.05538.06452
ENSG00000206557homo_sapiensENSP0000049271928.026913.9013homo_sapiensENSP0000037327214.40097.14286
ENSG00000206557homo_sapiensENSP0000027239528.026913.9013homo_sapiensENSP0000037327214.40097.14286
ENSG00000206557homo_sapiensENSP0000034050713.80957.2381homo_sapiensENSP0000037327216.70518.75576
ENSG00000206557homo_sapiensENSP0000037980030.737716.3934homo_sapiensENSP0000037327217.28119.21659
ENSG00000206557homo_sapiensENSP0000048181525.777812.8889homo_sapiensENSP0000037327213.36416.68203
ENSG00000206557homo_sapiensENSP0000033296926.503313.1403homo_sapiensENSP0000037327213.70976.79724
ENSG00000206557homo_sapiensENSP0000048376426.280612.9176homo_sapiensENSP0000037327213.59456.68203
ENSG00000206557homo_sapiensENSP0000033228430.615homo_sapiensENSP0000037327217.62678.64055
ENSG00000206557homo_sapiensENSP0000024436030.681817.8977homo_sapiensENSP0000037327212.44247.25806
ENSG00000206557homo_sapiensENSP0000049132026.923113.0342homo_sapiensENSP0000037327214.51617.02765
ENSG00000206557homo_sapiensENSP0000032391320.985411.8613homo_sapiensENSP0000037327213.24887.48848
ENSG00000206557homo_sapiensENSP0000036941529.329616.7598homo_sapiensENSP0000037327212.09686.91244
ENSG00000206557homo_sapiensENSP0000036329826.368212.9353homo_sapiensENSP0000037327212.2125.99078
ENSG00000206557homo_sapiensENSP0000037982631.395315.8915homo_sapiensENSP000003732729.33184.7235
ENSG00000206557homo_sapiensENSP0000032086921.904812.2222homo_sapiensENSP0000037327215.89868.87097
ENSG00000206557homo_sapiensENSP0000050855319.860611.8467homo_sapiensENSP000003732726.566823.91705
ENSG00000206557homo_sapiensENSP0000040829221.745810.8729homo_sapiensENSP0000037327216.35948.17972
ENSG00000206557homo_sapiensENSP0000026284316.73477.7551homo_sapiensENSP0000037327214.17056.56682
ENSG00000206557homo_sapiensENSP0000034420827.149313.5747homo_sapiensENSP0000037327213.82496.91244
ENSG00000206557homo_sapiensENSP0000039707330.145516.2162homo_sapiensENSP0000037327216.70518.98618
ENSG00000206557homo_sapiensENSP0000049718522.340411.7021homo_sapiensENSP0000037327214.51617.60369
ENSG00000206557homo_sapiensENSP0000028634916.18268.02213homo_sapiensENSP0000037327213.47936.68203
ENSG00000206557homo_sapiensENSP0000033965947.081731.9066homo_sapiensENSP0000037327241.820328.341
ENSG00000206557homo_sapiensENSP0000035565930.188716.1426homo_sapiensENSP0000037327216.58998.87097
ENSG00000206557homo_sapiensENSP0000025302414.25157.42515homo_sapiensENSP0000037327213.70977.14286
ENSG00000206557homo_sapiensENSP0000027477324.853215.2642homo_sapiensENSP0000037327214.63138.98618
ENSG00000206557homo_sapiensENSP0000050741330.434813.5011homo_sapiensENSP0000037327215.32266.79724
ENSG00000206557homo_sapiensENSP0000041044624.675312.0594homo_sapiensENSP0000037327215.32267.48848
ENSG00000206557homo_sapiensENSP0000030192430.020315.8215homo_sapiensENSP0000037327217.05078.98618
ENSG00000206557homo_sapiensENSP0000036339030.878217.847homo_sapiensENSP0000037327212.55767.25806
ENSG00000206557homo_sapiensENSP0000036929927.309215.0602homo_sapiensENSP0000037327215.66828.64055
ENSG00000206557homo_sapiensENSP0000031267819.04059.14543homo_sapiensENSP0000037327214.63137.02765
ENSG00000206557homo_sapiensENSP0000032773832.051316.0256homo_sapiensENSP0000037327217.28118.64055
ENSG00000206557homo_sapiensENSP0000033021625.221211.9469homo_sapiensENSP0000037327213.13366.2212
ENSG00000206557homo_sapiensENSP0000038829925.221212.6106homo_sapiensENSP0000037327213.13366.56682
ENSG00000206557homo_sapiensENSP0000032760425.221212.6106homo_sapiensENSP0000037327213.13366.56682
ENSG00000206557homo_sapiensENSP0000026938333.849118.7621homo_sapiensENSP0000037327220.161311.1751
ENSG00000206557homo_sapiensENSP0000030074727.422714.0206homo_sapiensENSP0000037327215.32267.8341
ENSG00000206557homo_sapiensENSP0000039508626.548713.0531homo_sapiensENSP0000037327213.82496.79724
ENSG00000206557homo_sapiensENSP0000049705027.212413.0531homo_sapiensENSP0000037327214.17056.79724
ENSG00000206557homo_sapiensENSP0000027573625.105513.5021homo_sapiensENSP0000037327213.70977.37327
ENSG00000206557homo_sapiensENSP0000033465720.421611.4625homo_sapiensENSP0000037327217.857110.023
ENSG00000206557homo_sapiensENSP0000035543731.0716.4609homo_sapiensENSP0000037327217.39639.21659
ENSG00000206557homo_sapiensENSP0000036592426.588213.6471homo_sapiensENSP0000037327213.01846.68203
ENSG00000206557homo_sapiensENSP0000021959614.85286.14597homo_sapiensENSP0000037327213.36415.52995
ENSG00000206557homo_sapiensENSP0000036944027.325613.7597homo_sapiensENSP0000037327216.24428.17972
ENSG00000206557homo_sapiensENSP00000516963100100homo_sapiensENSP00000373272100100

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000206557homo_sapiensENSP0000037327299.769699.424nomascus_leucogenysENSNLEP0000000536099.769699.424
ENSG00000206557homo_sapiensENSP0000037327285.599185.5991pan_paniscusENSPPAP0000001027899.865699.8656
ENSG00000206557homo_sapiensENSP0000037327299.654499.6544pongo_abeliiENSPPYP0000001570499.654499.6544
ENSG00000206557homo_sapiensENSP00000373272100100pan_troglodytesENSPTRP00000051497100100
ENSG00000206557homo_sapiensENSP00000373272100100gorilla_gorillaENSGGOP00000016715100100
ENSG00000206557homo_sapiensENSP0000037327291.013887.3272ornithorhynchus_anatinusENSOANP0000004269886.338882.8415
ENSG00000206557homo_sapiensENSP0000037327289.285784.5622sarcophilus_harrisiiENSSHAP0000003410078.441374.2915
ENSG00000206557homo_sapiensENSP0000037327270.967767.5115notamacropus_eugeniiENSMEUP0000000880784.965580.8276
ENSG00000206557homo_sapiensENSP0000037327266.820366.3594choloepus_hoffmanniENSCHOP0000000977099.485498.7993
ENSG00000206557homo_sapiensENSP0000037327268.778867.1659dasypus_novemcinctusENSDNOP0000002333995.5293.28
ENSG00000206557homo_sapiensENSP0000037327264.400963.1336erinaceus_europaeusENSEEUP0000000461898.763396.8198
ENSG00000206557homo_sapiensENSP0000037327299.308899.1936callithrix_jacchusENSCJAP0000002187999.308899.1936
ENSG00000206557homo_sapiensENSP0000037327299.539299.3088cercocebus_atysENSCATP0000003377399.539299.3088
ENSG00000206557homo_sapiensENSP0000037327299.193699.0783macaca_mulattaENSMMUP0000000603799.193699.0783
ENSG00000206557homo_sapiensENSP0000037327299.193699.0783macaca_nemestrinaENSMNEP0000001201899.193699.0783
ENSG00000206557homo_sapiensENSP0000037327299.539299.3088papio_anubisENSPANP0000002576099.539299.3088
ENSG00000206557homo_sapiensENSP0000037327271.313471.0829mandrillus_leucophaeusENSMLEP0000001407899.838799.5161
ENSG00000206557homo_sapiensENSP0000037327259.792659.2166tursiops_truncatusENSTTRP0000001590884.665683.8499
ENSG00000206557homo_sapiensENSP0000037327264.746563.9401vulpes_vulpesENSVVUP0000003024799.293398.0565
ENSG00000206557homo_sapiensENSP0000037327294.585391.3594mus_spretusMGP_SPRETEiJ_P009419496.023492.7485
ENSG00000206557homo_sapiensENSP0000037327298.732798.2719equus_asinusENSEASP0000500861898.846698.3852
ENSG00000206557homo_sapiensENSP0000037327298.156796.8894capra_hircusENSCHIP0000001943897.260396.0046
ENSG00000206557homo_sapiensENSP0000037327275.57674.8848loxodonta_africanaENSLAFP0000002938998.203697.3054
ENSG00000206557homo_sapiensENSP0000037327293.89492.8571panthera_leoENSPLOP0000000903497.839196.7587
ENSG00000206557homo_sapiensENSP0000037327287.096885.5991ailuropoda_melanoleucaENSAMEP0000004053293.103491.5025
ENSG00000206557homo_sapiensENSP0000037327298.732798.0415bos_indicus_hybridENSBIXP0000503673997.83197.1461
ENSG00000206557homo_sapiensENSP0000037327289.746588.4793oryctolagus_cuniculusENSOCUP0000001964285.604484.3956
ENSG00000206557homo_sapiensENSP0000037327298.847998.3871equus_caballusENSECAP0000001826298.847998.3871
ENSG00000206557homo_sapiensENSP0000037327297.926396.8894canis_lupus_familiarisENSCAFP0084503267597.926396.8894
ENSG00000206557homo_sapiensENSP0000037327288.018486.4055panthera_pardusENSPPRP0000001849994.32192.5926
ENSG00000206557homo_sapiensENSP0000037327298.502397.5806marmota_marmota_marmotaENSMMMP0000001555998.38997.4684
ENSG00000206557homo_sapiensENSP0000037327298.387197.8111balaenoptera_musculusENSBMSP0001001549397.935897.3624
ENSG00000206557homo_sapiensENSP0000037327297.695996.5438cavia_porcellusENSCPOP0000000405697.921596.7667
ENSG00000206557homo_sapiensENSP0000037327298.271997.235felis_catusENSFCAP0000000268897.597396.5675
ENSG00000206557homo_sapiensENSP0000037327297.004696.0829ursus_americanusENSUAMP0000003088598.135297.2028
ENSG00000206557homo_sapiensENSP0000037327281.68276.7281monodelphis_domesticaENSMODP0000003239082.155377.1727
ENSG00000206557homo_sapiensENSP0000037327278.456277.765bison_bison_bisonENSBBBP0000001041680.023579.3185
ENSG00000206557homo_sapiensENSP0000037327298.502397.8111monodon_monocerosENSMMNP0001502102798.050597.3624
ENSG00000206557homo_sapiensENSP0000037327298.502397.8111sus_scrofaENSSSCP0000005049098.38997.6985
ENSG00000206557homo_sapiensENSP0000037327299.078398.6175microcebus_murinusENSMICP0000005161198.850698.3908
ENSG00000206557homo_sapiensENSP0000037327295.737394.8157octodon_degusENSODEP0000000669698.11197.1665
ENSG00000206557homo_sapiensENSP0000037327297.580695.2765jaculus_jaculusENSJJAP0000002050996.689594.4064
ENSG00000206557homo_sapiensENSP0000037327298.156796.7742ovis_aries_rambouilletENSOARP0002003215197.260395.8904
ENSG00000206557homo_sapiensENSP0000037327282.949380.2995ochotona_princepsENSOPRP0000000461583.429980.7648
ENSG00000206557homo_sapiensENSP0000037327298.617597.9263delphinapterus_leucasENSDLEP0000002368198.165197.4771
ENSG00000206557homo_sapiensENSP0000037327298.387197.8111physeter_catodonENSPCTP0000501289298.160997.5862
ENSG00000206557homo_sapiensENSP0000037327294.239691.2442mus_caroliMGP_CAROLIEiJ_P009045795.672592.6316
ENSG00000206557homo_sapiensENSP0000037327294.585391.3594mus_musculusENSMUSP0000010744796.023492.7485
ENSG00000206557homo_sapiensENSP0000037327295.506994.3548dipodomys_ordiiENSDORP0000001279898.456197.2684
ENSG00000206557homo_sapiensENSP0000037327258.986258.1797mustela_putorius_furoENSMPUP0000001302999.610998.249
ENSG00000206557homo_sapiensENSP0000037327296.313495.7373aotus_nancymaaeENSANAP0000000932496.313495.7373
ENSG00000206557homo_sapiensENSP0000037327282.373380.6452saimiri_boliviensis_boliviensisENSSBOP0000003652584.715682.9384
ENSG00000206557homo_sapiensENSP0000037327299.539299.424chlorocebus_sabaeusENSCSAP0000000576399.539299.424
ENSG00000206557homo_sapiensENSP0000037327251.728151.1521tupaia_belangeriENSTBEP0000000547982.385381.4679
ENSG00000206557homo_sapiensENSP0000037327290.668287.6728mesocricetus_auratusENSMAUP0000001268495.509792.3544
ENSG00000206557homo_sapiensENSP0000037327298.271997.4654phocoena_sinusENSPSNP0000001260797.933497.1297
ENSG00000206557homo_sapiensENSP0000037327288.594586.6359camelus_dromedariusENSCDRP0000501631688.901786.9364
ENSG00000206557homo_sapiensENSP0000037327267.165966.5899carlito_syrichtaENSTSYP0000003499499.828898.9726
ENSG00000206557homo_sapiensENSP0000037327265.783462.9032panthera_tigris_altaicaENSPTIP0000002039890.205486.2559
ENSG00000206557homo_sapiensENSP0000037327294.585392.5115rattus_norvegicusENSRNOP0000004408996.023493.9181
ENSG00000206557homo_sapiensENSP0000037327299.193698.7327prolemur_simusENSPSMP0000003606999.193698.7327
ENSG00000206557homo_sapiensENSP0000037327294.930992.5115microtus_ochrogasterENSMOCP0000002113696.374393.9181
ENSG00000206557homo_sapiensENSP0000037327257.027656.106sorex_araneusENSSARP0000001076187.610686.1947
ENSG00000206557homo_sapiensENSP0000037327292.281189.5161peromyscus_maniculatus_bairdiiENSPEMP0000001215095.813492.9426
ENSG00000206557homo_sapiensENSP0000037327281.10680.4147bos_mutusENSBMUP0000001140580.826680.1378
ENSG00000206557homo_sapiensENSP0000037327258.525356.106mus_spicilegusENSMSIP0000000820698.832794.7471
ENSG00000206557homo_sapiensENSP0000037327295.046192.3963cricetulus_griseus_chok1gshdENSCGRP0000102823996.491293.8012
ENSG00000206557homo_sapiensENSP0000037327298.156797.235pteropus_vampyrusENSPVAP0000000392897.93197.0115
ENSG00000206557homo_sapiensENSP0000037327294.009292.1659myotis_lucifugusENSMLUP0000002163993.685491.8484
ENSG00000206557homo_sapiensENSP0000037327298.732797.6959rhinolophus_ferrumequinumENSRFEP0001000962798.732797.6959
ENSG00000206557homo_sapiensENSP0000037327298.387197.5806neovison_visonENSNVIP0000000719897.045596.25
ENSG00000206557homo_sapiensENSP0000037327298.732798.0415bos_taurusENSBTAP0000003084297.83197.1461
ENSG00000206557homo_sapiensENSP0000037327298.963198.1567heterocephalus_glaber_femaleENSHGLP0000000240998.849398.0437
ENSG00000206557homo_sapiensENSP0000037327285.944785.9447rhinopithecus_bietiENSRBIP0000001387099.599599.5995
ENSG00000206557homo_sapiensENSP0000037327297.926396.8894canis_lupus_dingoENSCAFP0002000278397.926396.8894
ENSG00000206557homo_sapiensENSP0000037327299.078398.1567sciurus_vulgarisENSSVLP0000502167998.964398.0437
ENSG00000206557homo_sapiensENSP0000037327289.746584.7926phascolarctos_cinereusENSPCIP0000003537279.979575.5647
ENSG00000206557homo_sapiensENSP0000037327267.281165.8986nannospalax_galiliENSNGAP0000000928410097.9452
ENSG00000206557homo_sapiensENSP0000037327298.617597.9263bos_grunniensENSBGRP0000003639897.828697.1429
ENSG00000206557homo_sapiensENSP0000037327291.12990.6682chinchilla_lanigeraENSCLAP0000000601498.87598.375
ENSG00000206557homo_sapiensENSP0000037327289.97789.1705cervus_hanglu_yarkandensisENSCHYP0000004072798.486897.604
ENSG00000206557homo_sapiensENSP0000037327298.387197.5806catagonus_wagneriENSCWAP0000002606098.387197.5806
ENSG00000206557homo_sapiensENSP0000037327298.732797.6959ictidomys_tridecemlineatusENSSTOP0000001360798.732797.6959
ENSG00000206557homo_sapiensENSP0000037327287.096884.9078otolemur_garnettiiENSOGAP0000001384387.90785.6977
ENSG00000206557homo_sapiensENSP0000037327299.308898.9631cebus_imitatorENSCCAP0000001356099.308898.9631
ENSG00000206557homo_sapiensENSP0000037327298.847997.9263urocitellus_parryiiENSUPAP0001000330898.620797.7011
ENSG00000206557homo_sapiensENSP0000037327298.847998.1567moschus_moschiferusENSMMSP0000002841497.833597.1494
ENSG00000206557homo_sapiensENSP0000037327273.041571.4286rhinopithecus_roxellanaENSRROP0000004000586.61284.6995
ENSG00000206557homo_sapiensENSP0000037327294.585391.7051mus_pahariMGP_PahariEiJ_P002613596.023493.0994
ENSG00000206557homo_sapiensENSP0000037327299.078398.7327propithecus_coquereliENSPCOP0000000111399.078398.7327
ENSG00000206557homo_sapiensENSP0000037327252.073738.2488ciona_intestinalisENSCINP0000002331066.568548.8954
ENSG00000206557homo_sapiensENSP0000037327272.926360.9447callorhinchus_miliiENSCMIP0000003293576.820464.199
ENSG00000206557homo_sapiensENSP0000037327283.755877.0737latimeria_chalumnaeENSLACP0000001157586.444779.5482
ENSG00000206557homo_sapiensENSP0000037327281.68273.3871lepisosteus_oculatusENSLOCP0000000142586.56977.7778
ENSG00000206557homo_sapiensENSP0000037327279.953970.8525clupea_harengusENSCHAP0000004033284.531174.9086
ENSG00000206557homo_sapiensENSP0000037327279.838771.3134danio_rerioENSDARP0000010178784.101975.1214
ENSG00000206557homo_sapiensENSP0000037327279.493170.9677carassius_auratusENSCARP0000003302584.146375.1219
ENSG00000206557homo_sapiensENSP0000037327280.299571.1982carassius_auratusENSCARP0000003515484.587475
ENSG00000206557homo_sapiensENSP0000037327280.184371.5438astyanax_mexicanusENSAMXP0000000016485.714376.4778
ENSG00000206557homo_sapiensENSP0000037327267.626753.917astyanax_mexicanusENSAMXP0000004030375.741960.3871
ENSG00000206557homo_sapiensENSP0000037327279.493170.9677ictalurus_punctatusENSIPUP0000001450085.290576.1434
ENSG00000206557homo_sapiensENSP0000037327280.299570.2765esox_luciusENSELUP0000004313278.668268.8488
ENSG00000206557homo_sapiensENSP0000037327267.972455.8756electrophorus_electricusENSEEEP0000002567872.749759.8027
ENSG00000206557homo_sapiensENSP0000037327279.493170.6221electrophorus_electricusENSEEEP0000002590984.870875.3998
ENSG00000206557homo_sapiensENSP0000037327271.198262.9032oncorhynchus_kisutchENSOKIP0000507972779.84570.5426
ENSG00000206557homo_sapiensENSP0000037327278.110666.9355oncorhynchus_kisutchENSOKIP0000506946381.490469.8317
ENSG00000206557homo_sapiensENSP0000037327258.525352.5346oncorhynchus_kisutchENSOKIP0000506407485.95677.1574
ENSG00000206557homo_sapiensENSP0000037327279.262768.894oncorhynchus_kisutchENSOKIP0000501109682.002471.2753
ENSG00000206557homo_sapiensENSP0000037327278.225866.5899oncorhynchus_mykissENSOMYP0000013810181.512669.3878
ENSG00000206557homo_sapiensENSP0000037327275.460866.4747oncorhynchus_mykissENSOMYP0000013342979.201969.7703
ENSG00000206557homo_sapiensENSP0000037327275.460866.3594oncorhynchus_mykissENSOMYP0000004025778.915769.3976
ENSG00000206557homo_sapiensENSP0000037327279.147568.6636oncorhynchus_mykissENSOMYP0000013416081.883271.0369
ENSG00000206557homo_sapiensENSP0000037327279.262768.6636salmo_salarENSSSAP0000011110282.002471.0369
ENSG00000206557homo_sapiensENSP0000037327275.345666.8203salmo_salarENSSSAP0000015215779.08170.133
ENSG00000206557homo_sapiensENSP0000037327275.921767.1659salmo_salarENSSSAP0000015764479.589470.4106
ENSG00000206557homo_sapiensENSP0000037327278.225867.2811salmo_salarENSSSAP0000003688582.402970.8738
ENSG00000206557homo_sapiensENSP0000037327278.110667.0507salmo_truttaENSSTUP0000009997081.392669.868
ENSG00000206557homo_sapiensENSP0000037327263.133653.5714salmo_truttaENSSTUP0000000768072.200361.2648
ENSG00000206557homo_sapiensENSP0000037327279.262768.6636salmo_truttaENSSTUP0000004802682.002471.0369
ENSG00000206557homo_sapiensENSP0000037327276.036967.5115salmo_truttaENSSTUP0000004132679.710170.7729
ENSG00000206557homo_sapiensENSP0000037327278.225868.5484gadus_morhuaENSGMOP0000004286780.450270.4976
ENSG00000206557homo_sapiensENSP0000037327278.571469.0092fundulus_heteroclitusENSFHEP0000001537182.168772.1687
ENSG00000206557homo_sapiensENSP0000037327277.649865.8986poecilia_reticulataENSPREP0000002658781.107168.8327
ENSG00000206557homo_sapiensENSP0000037327278.225868.318xiphophorus_maculatusENSXMAP0000000038881.708871.3598
ENSG00000206557homo_sapiensENSP0000037327278.571469.1244oryzias_latipesENSORLP0000004005782.566672.6392
ENSG00000206557homo_sapiensENSP0000037327280.414769.8157cyclopterus_lumpusENSCLMP0000504395182.408571.5466
ENSG00000206557homo_sapiensENSP0000037327280.414769.7005oreochromis_niloticusENSONIP0000001942383.095272.0238
ENSG00000206557homo_sapiensENSP0000037327279.723569.0092haplochromis_burtoniENSHBUP0000001729382.676271.5651
ENSG00000206557homo_sapiensENSP0000037327279.032368.5484astatotilapia_callipteraENSACLP0000000790482.155771.2575
ENSG00000206557homo_sapiensENSP0000037327279.377968.894sparus_aurataENSSAUP0001001413081.538570.7692
ENSG00000206557homo_sapiensENSP0000037327278.917169.2396lates_calcariferENSLCAP0001005279882.530172.4096
ENSG00000206557homo_sapiensENSP0000037327282.373375.1152xenopus_tropicalisENSXETP0000011734983.821876.4361
ENSG00000206557homo_sapiensENSP0000037327289.400984.2166chrysemys_picta_belliiENSCPBP0000003242288.685783.5429
ENSG00000206557homo_sapiensENSP0000037327288.940183.2949sphenodon_punctatusENSSPUP0000000258687.927182.3462
ENSG00000206557homo_sapiensENSP0000037327262.78859.447crocodylus_porosusENSCPRP0000500689790.682285.8569
ENSG00000206557homo_sapiensENSP0000037327288.824983.1797notechis_scutatusENSNSUP0000000387287.31681.7667
ENSG00000206557homo_sapiensENSP0000037327288.248882.7189pseudonaja_textilisENSPTXP0000001815686.749781.3137
ENSG00000206557homo_sapiensENSP0000037327289.746584.9078anas_platyrhynchos_platyrhynchosENSAPLP0000000825985.79381.1674
ENSG00000206557homo_sapiensENSP0000037327290.322685.7143gallus_gallusENSGALP0001002505489.395784.8347
ENSG00000206557homo_sapiensENSP0000037327260.483956.9124meleagris_gallopavoENSMGAP0000001175590.673685.3195
ENSG00000206557homo_sapiensENSP0000037327277.995473.9631serinus_canariaENSSCAP0000000096090.266785.6
ENSG00000206557homo_sapiensENSP0000037327276.843372.4654anolis_carolinensisENSACAP0000001462584.00579.2191
ENSG00000206557homo_sapiensENSP0000037327275.230464.4009neolamprologus_brichardiENSNBRP0000002732480.617369.0123
ENSG00000206557homo_sapiensENSP0000037327288.594582.4885naja_najaENSNNAP0000002097686.696780.7215
ENSG00000206557homo_sapiensENSP0000037327288.709782.8341podarcis_muralisENSPMRP0000003371185.555679.8889
ENSG00000206557homo_sapiensENSP0000037327217.511516.9355geospiza_fortisENSGFOP0000000479198.064594.8387
ENSG00000206557homo_sapiensENSP0000037327288.824983.871taeniopygia_guttataENSTGUP0000000389187.813282.9157
ENSG00000206557homo_sapiensENSP0000037327282.142973.3871erpetoichthys_calabaricusENSECRP0000002722187.916278.545
ENSG00000206557homo_sapiensENSP0000037327278.571468.7788kryptolebias_marmoratusENSKMAP0000002953482.367172.1014
ENSG00000206557homo_sapiensENSP0000037327289.055382.8341salvator_merianaeENSSMRP0000001336684.480978.5792
ENSG00000206557homo_sapiensENSP0000037327278.571469.0092oryzias_javanicusENSOJAP0000002131680.235370.4706
ENSG00000206557homo_sapiensENSP0000037327279.493168.7788amphilophus_citrinellusENSACIP0000002204382.932771.7548
ENSG00000206557homo_sapiensENSP0000037327279.032369.2396dicentrarchus_labraxENSDLAP0000507861282.650672.4096
ENSG00000206557homo_sapiensENSP0000037327279.147569.3548amphiprion_perculaENSAPEP0000000257782.870972.6176
ENSG00000206557homo_sapiensENSP0000037327278.571469.1244oryzias_sinensisENSOSIP0000000794882.566672.6392
ENSG00000206557homo_sapiensENSP0000037327262.096859.447pelodiscus_sinensisENSPSIP0000000479393.739189.7391
ENSG00000206557homo_sapiensENSP0000037327269.239661.1751gopherus_evgoodeiENSGEVP0000503017872.848564.3636
ENSG00000206557homo_sapiensENSP0000037327258.064551.1521gopherus_evgoodeiENSGEVP0000502107879.746870.2532
ENSG00000206557homo_sapiensENSP0000037327289.170583.7558gopherus_evgoodeiENSGEVP0000502906688.356282.9909
ENSG00000206557homo_sapiensENSP0000037327251.152142.8571gopherus_evgoodeiENSGEVP0000502175461.241451.3103
ENSG00000206557homo_sapiensENSP0000037327249.42439.4009chelonoidis_abingdoniiENSCABP0000001468659.749347.6323
ENSG00000206557homo_sapiensENSP0000037327284.562279.2627chelonoidis_abingdoniiENSCABP0000002169285.747780.3738
ENSG00000206557homo_sapiensENSP0000037327279.377969.5853seriola_dumeriliENSSDUP0000000184583.01272.7711
ENSG00000206557homo_sapiensENSP0000037327278.571469.0092cottoperca_gobioENSCGOP0000000530282.168772.1687
ENSG00000206557homo_sapiensENSP0000037327266.935564.0553struthio_camelus_australisENSSCUP0000001968095.402391.2972
ENSG00000206557homo_sapiensENSP0000037327289.97785.1383anser_brachyrhynchusENSABRP0000000404387.45882.7548
ENSG00000206557homo_sapiensENSP0000037327275.921766.3594gasterosteus_aculeatusENSGACP0000001099179.878869.8182
ENSG00000206557homo_sapiensENSP0000037327263.824955.9908cynoglossus_semilaevisENSCSEP0000001650685.099874.6544
ENSG00000206557homo_sapiensENSP0000037327277.76566.129poecilia_formosaENSPFOP0000001399681.227469.0734
ENSG00000206557homo_sapiensENSP0000037327279.377970.2765myripristis_murdjanENSMMDP0000501115083.41473.8499
ENSG00000206557homo_sapiensENSP0000037327279.262769.7005sander_luciopercaENSSLUP0000005192882.791872.8038
ENSG00000206557homo_sapiensENSP0000037327289.285785.023strigops_habroptilaENSSHBP0000500425488.470384.2466
ENSG00000206557homo_sapiensENSP0000037327279.262769.3548amphiprion_ocellarisENSAOCP0000000831982.991672.6176
ENSG00000206557homo_sapiensENSP0000037327288.940183.871terrapene_carolina_triunguisENSTMTP0000003123888.329583.2952
ENSG00000206557homo_sapiensENSP0000037327275.806466.7051hucho_huchoENSHHUP0000003918680.146270.5238
ENSG00000206557homo_sapiensENSP0000037327276.267367.0507hucho_huchoENSHHUP0000004750079.663170.0361
ENSG00000206557homo_sapiensENSP0000037327271.774261.5207hucho_huchoENSHHUP0000004162077.972566.8335
ENSG00000206557homo_sapiensENSP0000037327280.990870.8525betta_splendensENSBSLP0000000468284.495273.9183
ENSG00000206557homo_sapiensENSP0000037327278.917170.3917pygocentrus_nattereriENSPNAP0000001536584.359675.2463
ENSG00000206557homo_sapiensENSP0000037327277.995468.7788anabas_testudineusENSATEP0000000858983.787173.8861
ENSG00000206557homo_sapiensENSP0000037327211.52075.29954ciona_savignyiENSCSAVP0000001682447.846922.0096
ENSG00000206557homo_sapiensENSP0000037327279.262769.2396seriola_lalandi_dorsalisENSSLDP0000000691683.29372.7603
ENSG00000206557homo_sapiensENSP0000037327278.801869.1244labrus_bergyltaENSLBEP0000003260284.444474.0741
ENSG00000206557homo_sapiensENSP0000037327279.953969.2396pundamilia_nyerereiENSPNYP0000000180882.717571.6329
ENSG00000206557homo_sapiensENSP0000037327279.147569.3548mastacembelus_armatusENSMAMP0000000824982.17772.0096
ENSG00000206557homo_sapiensENSP0000037327279.262769.5853stegastes_partitusENSSPAP0000001541282.791872.6835
ENSG00000206557homo_sapiensENSP0000037327269.815758.6406oncorhynchus_tshawytschaENSOTSP0000506001576.708964.4304
ENSG00000206557homo_sapiensENSP0000037327269.930961.7512oncorhynchus_tshawytschaENSOTSP0000503358378.423869.2506
ENSG00000206557homo_sapiensENSP0000037327279.262768.7788oncorhynchus_tshawytschaENSOTSP0000505595082.002471.1561
ENSG00000206557homo_sapiensENSP0000037327279.377969.2396acanthochromis_polyacanthusENSAPOP0000001805283.01272.4096
ENSG00000206557homo_sapiensENSP0000037327289.170584.9078aquila_chrysaetos_chrysaetosENSACCP0002000981087.358983.1828
ENSG00000206557homo_sapiensENSP0000037327279.147568.894nothobranchius_furzeriENSNFUP0001504318082.17771.5311
ENSG00000206557homo_sapiensENSP0000037327279.032368.894cyprinodon_variegatusENSCVAP0000000062982.057471.5311
ENSG00000206557homo_sapiensENSP0000037327279.262770.7373denticeps_clupeoidesENSDCDP0000000049784.520975.43
ENSG00000206557homo_sapiensENSP0000037327279.147569.5853larimichthys_croceaENSLCRP0000502102881.591471.734
ENSG00000206557homo_sapiensENSP0000037327279.493168.894takifugu_rubripesENSTRUP0000003412182.142971.1905
ENSG00000206557homo_sapiensENSP0000037327274.42470.9677ficedula_albicollisENSFALP0000000952889.226585.0829
ENSG00000206557homo_sapiensENSP0000037327278.571468.318hippocampus_comesENSHCOP0000001687582.267871.532
ENSG00000206557homo_sapiensENSP0000037327279.493171.1982cyprinus_carpio_carpioENSCCRP0000016182484.146375.3659
ENSG00000206557homo_sapiensENSP0000037327279.838771.0829cyprinus_carpio_carpioENSCCRP0000012788584.101974.8786
ENSG00000206557homo_sapiensENSP0000037327289.97785.3687coturnix_japonicaENSCJPP0000501549289.155384.589
ENSG00000206557homo_sapiensENSP0000037327277.76566.0138poecilia_latipinnaENSPLAP0000001363781.227468.9531
ENSG00000206557homo_sapiensENSP0000037327279.838771.3134sinocyclocheilus_grahamiENSSGRP0000003046184.409375.3959
ENSG00000206557homo_sapiensENSP0000037327279.953970.7373sinocyclocheilus_grahamiENSSGRP0000007034584.223374.5146
ENSG00000206557homo_sapiensENSP0000037327278.801868.4332maylandia_zebraENSMZEP0000501555082.014471.223
ENSG00000206557homo_sapiensENSP0000037327267.511559.9078tetraodon_nigroviridisENSTNIP0000001211486.558376.8095
ENSG00000206557homo_sapiensENSP0000037327273.387161.1751paramormyrops_kingsleyaeENSPKIP0000003180076.470663.7455
ENSG00000206557homo_sapiensENSP0000037327280.299571.0829paramormyrops_kingsleyaeENSPKIP0000000834685.416775.6127
ENSG00000206557homo_sapiensENSP0000037327279.723571.4286scleropages_formosusENSSFOP0001507198283.777275.0605
ENSG00000206557homo_sapiensENSP0000037327275.921763.8249scleropages_formosusENSSFOP0001500283481.057868.1427
ENSG00000206557homo_sapiensENSP0000037327283.179773.1567leptobrachium_leishanenseENSLLEP0000004070180.580470.8705
ENSG00000206557homo_sapiensENSP0000037327279.493169.47scophthalmus_maximusENSSMAP0000003385982.142971.7857
ENSG00000206557homo_sapiensENSP0000037327278.917169.0092oryzias_melastigmaENSOMEP0000001091782.929872.5182

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0000082involved_in G1/S transition of mitotic cell cycle1ISSHomo_sapiens(9606)Process
GO:0000209involved_in protein polyubiquitination1IBAHomo_sapiens(9606)Process
GO:0000932located_in P-body2IDA,ISSHomo_sapiens(9606)Component
GO:0001843involved_in neural tube closure1IEAHomo_sapiens(9606)Process
GO:0004842enables ubiquitin-protein transferase activity1ISSHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0008270enables zinc ion binding1IEAHomo_sapiens(9606)Function
GO:0008543involved_in fibroblast growth factor receptor signaling pathway1ISSHomo_sapiens(9606)Process
GO:0010586involved_in miRNA metabolic process1ISSHomo_sapiens(9606)Process
GO:0010608involved_in post-transcriptional regulation of gene expression1IMPHomo_sapiens(9606)Process
GO:0017148involved_in negative regulation of translation1IDAHomo_sapiens(9606)Process
GO:0021915involved_in neural tube development1ISSHomo_sapiens(9606)Process
GO:0030371enables translation repressor activity1IDAHomo_sapiens(9606)Function
GO:0035196involved_in miRNA processing1IMPHomo_sapiens(9606)Process
GO:0035198enables miRNA binding2IDA,ISSHomo_sapiens(9606)Function
GO:0035278involved_in miRNA-mediated gene silencing by inhibition of translation1ISSHomo_sapiens(9606)Process
GO:0043161involved_in proteasome-mediated ubiquitin-dependent protein catabolic process1IBAHomo_sapiens(9606)Process
GO:0051865involved_in protein autoubiquitination1ISSHomo_sapiens(9606)Process
GO:0060964involved_in regulation of miRNA-mediated gene silencing1ISSHomo_sapiens(9606)Process
GO:0061158involved_in 3-UTR-mediated mRNA destabilization1IDAHomo_sapiens(9606)Process
GO:0061630enables ubiquitin protein ligase activity1IBAHomo_sapiens(9606)Function
GO:0071310involved_in cellular response to organic substance1IEAHomo_sapiens(9606)Process
GO:0072089involved_in stem cell proliferation1ISSHomo_sapiens(9606)Process
GO:2000177involved_in regulation of neural precursor cell proliferation1ISSHomo_sapiens(9606)Process
GO:2000637involved_in positive regulation of miRNA-mediated gene silencing1IEAHomo_sapiens(9606)Process

Expression