RBP Type	Canonical_RBPs
Diseases	Disease
Drug	N.A.
Main interacting RNAs	N.A.
Moonlighting functions	Metabolic enzyme
Localizations	N.A.
BulkPerturb-seq

Ensembl ID	ENSG00000204084	Gene ID	3633	Accession	6077
Symbol	INPP5B	Alias	5PTase	Full Name	inositol polyphosphate-5-phosphatase B
Status	Confidence	Length	86361 bases	Strand	Minus strand
Position	1 : 37860697 - 37947057	RNA binding domain	Exo_endo_phos
Summary	This gene encodes a member of a family of inositol polyphosphate-5-phosphatases. These enzymes function in the regulation of calcium signaling by inactivating inositol phosphates. The encoded protein is localized to the cytosol and mitochondria, and associates with membranes through an isoprenyl modification near the C-terminus. Alternatively spliced transcript variants of this gene have been described. [provided by RefSeq, Jul 2014]

Protein	Domain	Pfam ID	E-value	Domain number
ENSP00000397748	Exo_endo_phos	PF03372	1.7e-14	1
ENSP00000362118	Exo_endo_phos	PF03372	2.3e-14	1
ENSP00000362115	Exo_endo_phos	PF03372	2.6e-14	1
ENSP00000362114	Exo_endo_phos	PF03372	3e-14	1
ENSP00000362117	Exo_endo_phos	PF03372	3e-14	1

Pubmed ID	Full Name	Cell	Author	Time	Doi

Pubmed ID	Title	Author	Time	Journal

Name	Transcript ID	bp	Protein	Translation ID
INPP5B-204	ENST00000373027	3905	749aa	ENSP00000362118
INPP5B-202	ENST00000373024	4450	913aa	ENSP00000362115
INPP5B-203	ENST00000373026	3230	993aa	ENSP00000362117
INPP5B-208	ENST00000487328	629	No protein	-
INPP5B-206	ENST00000470364	439	No protein	-
INPP5B-207	ENST00000474758	572	No protein	-
INPP5B-205	ENST00000467066	651	No protein	-
INPP5B-201	ENST00000373021	3934	319aa	ENSP00000362112
INPP5B-209	ENST00000491406	586	No protein	-

Pathway ID	Pathway Name	Source

ensgID	Trait	pValue	Pubmed ID

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0001701	involved_in in utero embryonic development	1	IEA	Homo_sapiens(9606)	Process
GO:0004439	enables phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	2	IBA,IDA	Homo_sapiens(9606)	Function
GO:0005515	enables protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0005793	located_in endoplasmic reticulum-Golgi intermediate compartment	1	IEA	Homo_sapiens(9606)	Component
GO:0005794	located_in Golgi apparatus	1	IEA	Homo_sapiens(9606)	Component
GO:0005829	is_active_in cytosol	2	IBA,IDA	Homo_sapiens(9606)	Component
GO:0005886	located_in plasma membrane	1	TAS	Homo_sapiens(9606)	Component
GO:0007165	involved_in signal transduction	1	IEA	Homo_sapiens(9606)	Process
GO:0007283	involved_in spermatogenesis	1	IEA	Homo_sapiens(9606)	Process
GO:0016020	is_active_in membrane	2	IBA,IDA	Homo_sapiens(9606)	Component
GO:0030317	involved_in flagellated sperm motility	1	IEA	Homo_sapiens(9606)	Process
GO:0030670	located_in phagocytic vesicle membrane	1	IEA	Homo_sapiens(9606)	Component
GO:0031901	located_in early endosome membrane	1	IEA	Homo_sapiens(9606)	Component
GO:0043647	involved_in inositol phosphate metabolic process	1	TAS	Homo_sapiens(9606)	Process
GO:0046856	involved_in phosphatidylinositol dephosphorylation	2	IBA,IDA	Homo_sapiens(9606)	Process
GO:0046872	enables metal ion binding	1	IEA	Homo_sapiens(9606)	Function
GO:0052658	enables inositol-1,4,5-trisphosphate 5-phosphatase activity	3	IBA,IDA,TAS	Homo_sapiens(9606)	Function
GO:0052659	enables inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity	1	TAS	Homo_sapiens(9606)	Function
GO:0070613	involved_in regulation of protein processing	1	IEA	Homo_sapiens(9606)	Process