RBPWorld - a comprehensive database of RNA Binding Proteins

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Functions and Diseases

RBP Type	Canonical_RBPs
Diseases	N.A.
Drug	N.A.
Main interacting RNAs	tRNA
Moonlighting functions	N.A.
Localizations	N.A.
BulkPerturb-seq

Description

Ensembl ID	ENSG00000203791	Gene ID	399818	Accession	33787
Symbol	EEF1AKMT2	Alias	Efm4;METTL10;C10orf138	Full Name	EEF1A lysine methyltransferase 2
Status	Confidence	Length	43739 bases	Strand	Minus strand
Position	10 : 124748149 - 124791887	RNA binding domain	Methyltransf_31 , MTS
Summary	Enables protein-lysine N-methyltransferase activity. Involved in peptidyl-lysine methylation. Located in cytosol and nuclear body. [provided by Alliance of Genome Resources, Apr 2022]

RNA binding domains (RBDs)

Protein	Domain	Pfam ID	E-value	Domain number
ENSP00000498289	Methyltransf_31	PF13847	7.8e-21	1
ENSP00000498289	MTS	PF05175	0.00021	2
ENSP00000357829	Methyltransf_31	PF13847	2.1e-20	1

RNA binding proteomes (RBPomes)

Pubmed ID	Full Name	Cell	Author	Time	Doi

Literatures on RNA binding capacity

Pubmed ID	Title	Author	Time	Journal

Transcripts

Name	Transcript ID	bp	Protein	Translation ID
EEF1AKMT2-205	ENST00000495711	524	31aa	ENSP00000470332
EEF1AKMT2-203	ENST00000466270	3587	104aa	ENSP00000451190
EEF1AKMT2-201	ENST00000368836	3599	291aa	ENSP00000357829
EEF1AKMT2-207	ENST00000652548	3340	236aa	ENSP00000498289
EEF1AKMT2-202	ENST00000464099	1013	104aa	ENSP00000450447
EEF1AKMT2-206	ENST00000498770	787	No protein	-
EEF1AKMT2-204	ENST00000468738	430	No protein	-

Gene Model

Click here to download ENSG00000203791's gene model file

Pathways

Pathway ID	Pathway Name	Source

Phenotypes

ensgID	Trait	pValue	Pubmed ID

GWAS

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Protein-Protein Interaction (PPI)

Click here to download ENSG00000203791's PPI file

Paralogs

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Orthologs

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Gene Ontology

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0005634	located_in nucleus	1	IDA	Homo_sapiens(9606)	Component
GO:0005654	located_in nucleoplasm	1	IDA	Homo_sapiens(9606)	Component
GO:0005737	is_active_in cytoplasm	2	IBA,IDA	Homo_sapiens(9606)	Component
GO:0005829	located_in cytosol	2	IDA,TAS	Homo_sapiens(9606)	Component
GO:0006338	involved_in chromatin remodeling	1	IEA	Homo_sapiens(9606)	Process
GO:0006479	involved_in protein methylation	1	TAS	Homo_sapiens(9606)	Process
GO:0008168	enables methyltransferase activity	1	IDA	Homo_sapiens(9606)	Function
GO:0016279	enables protein-lysine N-methyltransferase activity	3	IBA,IDA,TAS	Homo_sapiens(9606)	Function
GO:0018022	involved_in peptidyl-lysine methylation	1	IDA	Homo_sapiens(9606)	Process
GO:0042054	enables histone methyltransferase activity	1	IEA	Homo_sapiens(9606)	Function

Expression