RBP Type	Canonical_RBPs
Diseases	Cancer
Drug	N.A.
Main interacting RNAs	N.A.
Moonlighting functions	E3 ligase
Localizations	N.A.
BulkPerturb-seq	N.A.

Ensembl ID	ENSG00000198625	Gene ID	4194	Accession	6974
Symbol	MDM4	Alias	HDMX;MDMX;MRP1;BMFS6	Full Name	MDM4 regulator of p53
Status	Confidence	Length	41742 bases	Strand	Plus strand
Position	1 : 204516379 - 204558120	RNA binding domain	zf-RanBP
Summary	This gene encodes a nuclear protein that contains a p53 binding domain at the N-terminus and a RING finger domain at the C-terminus, and shows structural similarity to p53-binding protein MDM2. Both proteins bind the p53 tumor suppressor protein and inhibit its activity, and have been shown to be overexpressed in a variety of human cancers. However, unlike MDM2 which degrades p53, this protein inhibits p53 by binding its transcriptional activation domain. This protein also interacts with MDM2 protein via the RING finger domain, and inhibits the latter's degradation. So this protein can reverse MDM2-targeted degradation of p53, while maintaining suppression of p53 transactivation and apoptotic functions. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Feb 2011]

Protein	Domain	Pfam ID	E-value	Domain number
ENSP00000395254	zf-RanBP	PF00641	7.7e-09	1
ENSP00000478080	zf-RanBP	PF00641	2.6e-08	1
ENSP00000356147	zf-RanBP	PF00641	4e-08	1
ENSP00000482388	zf-RanBP	PF00641	4.3e-08	1
ENSP00000396840	zf-RanBP	PF00641	5e-08	1
ENSP00000356150	zf-RanBP	PF00641	5.7e-08	1

Pubmed ID	Full Name	Cell	Author	Time	Doi

Pubmed ID	Title	Author	Time	Journal
36566308	MDM4: What do we know about the association between its polymorphisms and cancer?	Mattevi Gabriela Almeida	2022-12-24	Medical oncology (Northwood, London, England)
36559315	Extracellular Vesicles as Drug Targets and Delivery Vehicles for Cancer Therapy.	V Sai Chitti	2022-12-16	Pharmaceutics
33429878	Serum Response Factor (SRF) Drives the Transcriptional Upregulation of the MDM4 Oncogene in HCC.	Rossella Pellegrino	2021-01-08	Cancers

Name	Transcript ID	bp	Protein	Translation ID
MDM4-204	ENST00000367183	9098	164aa	ENSP00000356151
MDM4-205	ENST00000391947	10008	140aa	ENSP00000375811
MDM4-207	ENST00000454264	9926	440aa	ENSP00000396840
MDM4-214	ENST00000612738	9407	267aa	ENSP00000478080
MDM4-215	ENST00000614459	9782	392aa	ENSP00000482388
MDM4-216	ENST00000616250	9597	116aa	ENSP00000478581
MDM4-210	ENST00000470797	909	No protein	-
MDM4-209	ENST00000463049	6102	No protein	-
MDM4-203	ENST00000367182	10050	490aa	ENSP00000356150
MDM4-211	ENST00000470908	884	No protein	-
MDM4-212	ENST00000471783	552	No protein	-
MDM4-202	ENST00000367180	547	131aa	ENSP00000356148
MDM4-213	ENST00000507825	481	140aa	ENSP00000443816
MDM4-201	ENST00000367179	697	213aa	ENSP00000356147
MDM4-208	ENST00000462012	582	No protein	-
MDM4-206	ENST00000444261	513	171aa	ENSP00000395254

Pathway ID	Pathway Name	Source

ensgID	Trait	pValue	Pubmed ID
62613	Neuropsychological Tests	5E-6	19734545
65850	Breast Neoplasms	8E-18	27117709
66316	Breast Neoplasms	1E-7	23544013
66496	Education	3E-9	27225129
66916	Triple Negative Breast Neoplasms	4E-6	24325915
72853	Prostatic Neoplasms	2E-11	23535732
74681	Breast Neoplasms	2E-12	23535733
82177	Breast Neoplasms	6E-15	27117709
87248	Education	5E-8	25201988
100426	Education	3E-13	27225129
102247	Education	8E-12	23722424

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSG00000198625	homo_sapiens	ENSP00000258149	51.9115	31.7907	homo_sapiens	ENSP00000356150	52.6531	32.2449

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSG00000198625	homo_sapiens	ENSP00000356150	99.5918	99.5918	nomascus_leucogenys	ENSNLEP00000023664	99.5918	99.5918
ENSG00000198625	homo_sapiens	ENSP00000356150	99.7959	99.3878	pan_paniscus	ENSPPAP00000014717	99.7959	99.3878
ENSG00000198625	homo_sapiens	ENSP00000356150	99.1837	98.3673	pongo_abelii	ENSPPYP00000025178	95.2941	94.5098
ENSG00000198625	homo_sapiens	ENSP00000356150	99.7959	99.5918	pan_troglodytes	ENSPTRP00000051283	99.7959	99.5918
ENSG00000198625	homo_sapiens	ENSP00000356150	99.5918	99.5918	gorilla_gorilla	ENSGGOP00000012642	99.5918	99.5918
ENSG00000198625	homo_sapiens	ENSP00000356150	83.2653	73.6735	ornithorhynchus_anatinus	ENSOANP00000021247	83.6066	73.9754
ENSG00000198625	homo_sapiens	ENSP00000356150	84.0816	76.7347	sarcophilus_harrisii	ENSSHAP00000022748	80	73.0097
ENSG00000198625	homo_sapiens	ENSP00000356150	68.1633	62.2449	notamacropus_eugenii	ENSMEUP00000011513	68.7243	62.7572
ENSG00000198625	homo_sapiens	ENSP00000356150	53.6735	51.2245	choloepus_hoffmanni	ENSCHOP00000011595	93.2624	89.0071
ENSG00000198625	homo_sapiens	ENSP00000356150	95.102	90	dasypus_novemcinctus	ENSDNOP00000000641	94.9083	89.8167
ENSG00000198625	homo_sapiens	ENSP00000356150	71.6327	65.5102	erinaceus_europaeus	ENSEEUP00000012689	71.4868	65.3768
ENSG00000198625	homo_sapiens	ENSP00000356150	86.3265	80.8163	echinops_telfairi	ENSETEP00000009118	86.1507	80.6517
ENSG00000198625	homo_sapiens	ENSP00000356150	97.7551	94.898	callithrix_jacchus	ENSCJAP00000031287	97.7551	94.898
ENSG00000198625	homo_sapiens	ENSP00000356150	98.5714	98.1633	cercocebus_atys	ENSCATP00000009047	98.5714	98.1633
ENSG00000198625	homo_sapiens	ENSP00000356150	98.5714	98.1633	macaca_fascicularis	ENSMFAP00000000737	98.5714	98.1633
ENSG00000198625	homo_sapiens	ENSP00000356150	97.9592	97.3469	macaca_mulatta	ENSMMUP00000014729	96.9697	96.3636
ENSG00000198625	homo_sapiens	ENSP00000356150	89.3878	88.9796	macaca_nemestrina	ENSMNEP00000005994	98.427	97.9775
ENSG00000198625	homo_sapiens	ENSP00000356150	98.3673	97.9592	papio_anubis	ENSPANP00000028152	89.2593	88.8889
ENSG00000198625	homo_sapiens	ENSP00000356150	98.5714	98.1633	mandrillus_leucophaeus	ENSMLEP00000015714	98.5714	98.1633
ENSG00000198625	homo_sapiens	ENSP00000356150	92.8571	89.7959	tursiops_truncatus	ENSTTRP00000011544	92.668	89.613
ENSG00000198625	homo_sapiens	ENSP00000356150	95.7143	93.4694	vulpes_vulpes	ENSVVUP00000020126	95.7143	93.4694
ENSG00000198625	homo_sapiens	ENSP00000356150	90.6122	83.8775	mus_spretus	MGP_SPRETEiJ_P0020889	90.6122	83.8775
ENSG00000198625	homo_sapiens	ENSP00000356150	96.5306	94.898	equus_asinus	ENSEASP00005047737	84.3137	82.8877
ENSG00000198625	homo_sapiens	ENSP00000356150	94.6939	90.4082	capra_hircus	ENSCHIP00000006559	94.501	90.224
ENSG00000198625	homo_sapiens	ENSP00000356150	92.449	87.3469	loxodonta_africana	ENSLAFP00000001814	92.2607	87.169
ENSG00000198625	homo_sapiens	ENSP00000356150	95.7143	93.2653	panthera_leo	ENSPLOP00000029408	95.5193	93.0754
ENSG00000198625	homo_sapiens	ENSP00000356150	95.7143	93.2653	ailuropoda_melanoleuca	ENSAMEP00000001201	95.3252	92.8862
ENSG00000198625	homo_sapiens	ENSP00000356150	46.7347	44.0816	bos_indicus_hybrid	ENSBIXP00005025627	93.4694	88.1633
ENSG00000198625	homo_sapiens	ENSP00000356150	94.4898	90.2041	bos_indicus_hybrid	ENSBIXP00005007395	94.2974	90.0204
ENSG00000198625	homo_sapiens	ENSP00000356150	94.2857	90	oryctolagus_cuniculus	ENSOCUP00000000005	94.0937	89.8167
ENSG00000198625	homo_sapiens	ENSP00000356150	96.5306	94.898	equus_caballus	ENSECAP00000081706	83.4215	82.0106
ENSG00000198625	homo_sapiens	ENSP00000356150	96.1225	93.8775	canis_lupus_familiaris	ENSCAFP00845032370	95.7317	93.4959
ENSG00000198625	homo_sapiens	ENSP00000356150	95.7143	93.2653	panthera_pardus	ENSPPRP00000000052	95.5193	93.0754
ENSG00000198625	homo_sapiens	ENSP00000356150	31.8367	29.5918	marmota_marmota_marmota	ENSMMMP00000015853	78.392	72.8643
ENSG00000198625	homo_sapiens	ENSP00000356150	22.449	21.2245	marmota_marmota_marmota	ENSMMMP00000000281	90.9091	85.9504
ENSG00000198625	homo_sapiens	ENSP00000356150	27.551	24.898	marmota_marmota_marmota	ENSMMMP00000008567	88.8158	80.2632
ENSG00000198625	homo_sapiens	ENSP00000356150	95.5102	93.0612	balaenoptera_musculus	ENSBMSP00010001296	95.3157	92.8717
ENSG00000198625	homo_sapiens	ENSP00000356150	91.0204	85.7143	cavia_porcellus	ENSCPOP00000007397	91.9588	86.5979
ENSG00000198625	homo_sapiens	ENSP00000356150	95.7143	93.2653	felis_catus	ENSFCAP00000013777	95.5193	93.0754
ENSG00000198625	homo_sapiens	ENSP00000356150	95.5102	93.0612	ursus_americanus	ENSUAMP00000008722	95.1219	92.6829
ENSG00000198625	homo_sapiens	ENSP00000356150	84.898	77.1429	monodelphis_domestica	ENSMODP00000001964	85.2459	77.459
ENSG00000198625	homo_sapiens	ENSP00000356150	46.5306	44.0816	bison_bison_bison	ENSBBBP00000005226	93.0612	88.1633
ENSG00000198625	homo_sapiens	ENSP00000356150	94.4898	90.2041	bison_bison_bison	ENSBBBP00000008548	94.2974	90.0204
ENSG00000198625	homo_sapiens	ENSP00000356150	86.5306	82.6531	monodon_monoceros	ENSMMNP00015005804	79.5497	75.985
ENSG00000198625	homo_sapiens	ENSP00000356150	95.5102	92.2449	sus_scrofa	ENSSSCP00000016209	92.4901	89.3281
ENSG00000198625	homo_sapiens	ENSP00000356150	95.5102	92.6531	microcebus_murinus	ENSMICP00000015509	95.3157	92.4644
ENSG00000198625	homo_sapiens	ENSP00000356150	94.6939	89.3878	octodon_degus	ENSODEP00000018320	94.501	89.2057
ENSG00000198625	homo_sapiens	ENSP00000356150	89.5918	83.8775	jaculus_jaculus	ENSJJAP00000014771	89.4094	83.7067
ENSG00000198625	homo_sapiens	ENSP00000356150	94.2857	90	ovis_aries_rambouillet	ENSOARP00020006882	94.0937	89.8167
ENSG00000198625	homo_sapiens	ENSP00000356150	91.2245	88.5714	ursus_maritimus	ENSUMAP00000004359	91.7864	89.117
ENSG00000198625	homo_sapiens	ENSP00000356150	88.5714	85.5102	ochotona_princeps	ENSOPRP00000012653	93.3333	90.1075
ENSG00000198625	homo_sapiens	ENSP00000356150	95.5102	92.449	delphinapterus_leucas	ENSDLEP00000007442	95.3157	92.2607
ENSG00000198625	homo_sapiens	ENSP00000356150	45.7143	44.0816	physeter_catodon	ENSPCTP00005001549	89.6	86.4
ENSG00000198625	homo_sapiens	ENSP00000356150	95.102	92.6531	physeter_catodon	ENSPCTP00005025322	94.9083	92.4644
ENSG00000198625	homo_sapiens	ENSP00000356150	90.6122	84.0816	mus_caroli	MGP_CAROLIEiJ_P0019843	90.6122	84.0816
ENSG00000198625	homo_sapiens	ENSP00000356150	90.6122	84.0816	mus_musculus	ENSMUSP00000068661	90.6122	84.0816
ENSG00000198625	homo_sapiens	ENSP00000356150	89.1837	84.4898	dipodomys_ordii	ENSDORP00000006440	90.8524	86.0707
ENSG00000198625	homo_sapiens	ENSP00000356150	94.898	91.8367	mustela_putorius_furo	ENSMPUP00000011627	94.3205	91.2779
ENSG00000198625	homo_sapiens	ENSP00000356150	76.3265	72.2449	aotus_nancymaae	ENSANAP00000015747	89.9038	85.0962
ENSG00000198625	homo_sapiens	ENSP00000356150	95.3061	93.0612	aotus_nancymaae	ENSANAP00000038977	94.9187	92.6829
ENSG00000198625	homo_sapiens	ENSP00000356150	92.449	89.5918	saimiri_boliviensis_boliviensis	ENSSBOP00000006983	95.5696	92.616
ENSG00000198625	homo_sapiens	ENSP00000356150	97.7551	95.9184	saimiri_boliviensis_boliviensis	ENSSBOP00000040407	97.7551	95.9184
ENSG00000198625	homo_sapiens	ENSP00000356150	91.0204	87.7551	vicugna_pacos	ENSVPAP00000011197	95.2991	91.8803
ENSG00000198625	homo_sapiens	ENSP00000356150	98.7755	97.9592	chlorocebus_sabaeus	ENSCSAP00000010683	98.7755	97.9592
ENSG00000198625	homo_sapiens	ENSP00000356150	61.4286	57.9592	tupaia_belangeri	ENSTBEP00000010115	75.8186	71.5365
ENSG00000198625	homo_sapiens	ENSP00000356150	42.2449	39.3878	mesocricetus_auratus	ENSMAUP00000008248	87.7119	81.7797
ENSG00000198625	homo_sapiens	ENSP00000356150	42.0408	39.3878	mesocricetus_auratus	ENSMAUP00000019554	89.1775	83.5498
ENSG00000198625	homo_sapiens	ENSP00000356150	95.3061	92.2449	phocoena_sinus	ENSPSNP00000027992	95.112	92.057
ENSG00000198625	homo_sapiens	ENSP00000356150	95.9184	92.8571	camelus_dromedarius	ENSCDRP00005021862	95.723	92.668
ENSG00000198625	homo_sapiens	ENSP00000356150	95.9184	92.6531	carlito_syrichta	ENSTSYP00000021566	95.723	92.4644
ENSG00000198625	homo_sapiens	ENSP00000356150	93.0612	90.8163	panthera_tigris_altaica	ENSPTIP00000010699	94.2149	91.9421
ENSG00000198625	homo_sapiens	ENSP00000356150	90	84.0816	rattus_norvegicus	ENSRNOP00000012984	90	84.0816
ENSG00000198625	homo_sapiens	ENSP00000356150	96.3265	93.2653	prolemur_simus	ENSPSMP00000006547	96.1303	93.0754
ENSG00000198625	homo_sapiens	ENSP00000356150	92.0408	85.5102	microtus_ochrogaster	ENSMOCP00000002649	92.229	85.6851
ENSG00000198625	homo_sapiens	ENSP00000356150	88.9796	82.8571	sorex_araneus	ENSSARP00000003807	89.5277	83.3676
ENSG00000198625	homo_sapiens	ENSP00000356150	90.8163	85.9184	peromyscus_maniculatus_bairdii	ENSPEMP00000030271	90.8163	85.9184
ENSG00000198625	homo_sapiens	ENSP00000356150	46.3265	43.8776	bos_mutus	ENSBMUP00000008263	92.6531	87.7551
ENSG00000198625	homo_sapiens	ENSP00000356150	94.2857	90	bos_mutus	ENSBMUP00000024380	94.0937	89.8167
ENSG00000198625	homo_sapiens	ENSP00000356150	70.8163	62.449	mus_spicilegus	ENSMSIP00000001887	85.468	75.3695
ENSG00000198625	homo_sapiens	ENSP00000356150	88.5714	81.8367	mus_spicilegus	ENSMSIP00000027076	89.117	82.3409
ENSG00000198625	homo_sapiens	ENSP00000356150	90	83.8775	cricetulus_griseus_chok1gshd	ENSCGRP00001003570	90	83.8775
ENSG00000198625	homo_sapiens	ENSP00000356150	85.9184	82.449	pteropus_vampyrus	ENSPVAP00000005353	85.7434	82.2811
ENSG00000198625	homo_sapiens	ENSP00000356150	88.3673	81.6327	myotis_lucifugus	ENSMLUP00000006508	88.0081	81.3008
ENSG00000198625	homo_sapiens	ENSP00000356150	84.2857	76.5306	vombatus_ursinus	ENSVURP00010017132	84.1141	76.3747
ENSG00000198625	homo_sapiens	ENSP00000356150	91.0204	86.3265	rhinolophus_ferrumequinum	ENSRFEP00010021843	90.835	86.1507
ENSG00000198625	homo_sapiens	ENSP00000356150	51.6327	50.6122	neovison_vison	ENSNVIP00000021925	93.7037	91.8519
ENSG00000198625	homo_sapiens	ENSP00000356150	46.7347	44.0816	bos_taurus	ENSBTAP00000063059	93.4694	88.1633
ENSG00000198625	homo_sapiens	ENSP00000356150	94.0816	89.7959	bos_taurus	ENSBTAP00000008209	93.89	89.613
ENSG00000198625	homo_sapiens	ENSP00000356150	94.898	89.1837	heterocephalus_glaber_female	ENSHGLP00000039989	94.7047	89.002
ENSG00000198625	homo_sapiens	ENSP00000356150	98.9796	98.3673	rhinopithecus_bieti	ENSRBIP00000029889	98.9796	98.3673
ENSG00000198625	homo_sapiens	ENSP00000356150	66.3265	64.6939	canis_lupus_dingo	ENSCAFP00020007385	94.7522	92.4198
ENSG00000198625	homo_sapiens	ENSP00000356150	95.5102	91.8367	sciurus_vulgaris	ENSSVLP00005008679	95.5102	91.8367
ENSG00000198625	homo_sapiens	ENSP00000356150	83.8775	76.3265	phascolarctos_cinereus	ENSPCIP00000022982	83.7067	76.1711
ENSG00000198625	homo_sapiens	ENSP00000356150	86.1225	78.5714	procavia_capensis	ENSPCAP00000006557	86.4754	78.8934
ENSG00000198625	homo_sapiens	ENSP00000356150	92.8571	88.5714	nannospalax_galili	ENSNGAP00000009754	92.668	88.391
ENSG00000198625	homo_sapiens	ENSP00000356150	94.4898	90.2041	bos_grunniens	ENSBGRP00000015957	94.2974	90.0204
ENSG00000198625	homo_sapiens	ENSP00000356150	93.8775	88.7755	chinchilla_lanigera	ENSCLAP00000017463	93.6864	88.5947
ENSG00000198625	homo_sapiens	ENSP00000356150	94.2857	89.5918	cervus_hanglu_yarkandensis	ENSCHYP00000021986	94.0937	89.4094
ENSG00000198625	homo_sapiens	ENSP00000356150	93.6735	90.2041	catagonus_wagneri	ENSCWAP00000017947	93.4827	90.0204
ENSG00000198625	homo_sapiens	ENSP00000356150	95.5102	91.2245	ictidomys_tridecemlineatus	ENSSTOP00000003760	95.5102	91.2245
ENSG00000198625	homo_sapiens	ENSP00000356150	93.2653	89.5918	otolemur_garnettii	ENSOGAP00000010451	92.3232	88.6869
ENSG00000198625	homo_sapiens	ENSP00000356150	82.2449	78.9796	cebus_imitator	ENSCCAP00000034672	92.8571	89.1705
ENSG00000198625	homo_sapiens	ENSP00000356150	96.9388	95.102	cebus_imitator	ENSCCAP00000026541	97.5359	95.6879
ENSG00000198625	homo_sapiens	ENSP00000356150	95.3061	91.6327	urocitellus_parryii	ENSUPAP00010008534	95.3061	91.6327
ENSG00000198625	homo_sapiens	ENSP00000356150	94.2857	90.2041	moschus_moschiferus	ENSMMSP00000005320	94.0937	90.0204
ENSG00000198625	homo_sapiens	ENSP00000356150	98.9796	98.3673	rhinopithecus_roxellana	ENSRROP00000007643	98.9796	98.3673
ENSG00000198625	homo_sapiens	ENSP00000356150	90	82.8571	mus_pahari	MGP_PahariEiJ_P0075146	90.1841	83.0266
ENSG00000198625	homo_sapiens	ENSP00000356150	95.5102	93.4694	propithecus_coquereli	ENSPCOP00000024404	95.3157	93.279
ENSG00000198625	homo_sapiens	ENSP00000356150	39.1837	22.8571	ciona_intestinalis	ENSCINP00000002267	40.9382	23.8806
ENSG00000198625	homo_sapiens	ENSP00000356150	21.0204	15.3061	petromyzon_marinus	ENSPMAP00000008097	51.5	37.5
ENSG00000198625	homo_sapiens	ENSP00000356150	37.7551	21.2245	eptatretus_burgeri	ENSEBUP00000001731	43.6321	24.5283
ENSG00000198625	homo_sapiens	ENSP00000356150	59.7959	43.8776	callorhinchus_milii	ENSCMIP00000003384	59.5528	43.6992
ENSG00000198625	homo_sapiens	ENSP00000356150	61.2245	48.3673	latimeria_chalumnae	ENSLACP00000019637	61.0998	48.2688
ENSG00000198625	homo_sapiens	ENSP00000356150	64.6939	49.1837	lepisosteus_oculatus	ENSLOCP00000014779	64.8262	49.2843
ENSG00000198625	homo_sapiens	ENSP00000356150	61.8367	48.5714	clupea_harengus	ENSCHAP00000003889	60	47.1287
ENSG00000198625	homo_sapiens	ENSP00000356150	64.0816	49.3878	danio_rerio	ENSDARP00000074651	63.3064	48.7903
ENSG00000198625	homo_sapiens	ENSP00000356150	64.0816	49.1837	carassius_auratus	ENSCARP00000058956	62.9258	48.2966
ENSG00000198625	homo_sapiens	ENSP00000356150	64.4898	49.3878	carassius_auratus	ENSCARP00000063081	63.4538	48.5944
ENSG00000198625	homo_sapiens	ENSP00000356150	63.6735	47.7551	astyanax_mexicanus	ENSAMXP00000028812	63.9344	47.9508
ENSG00000198625	homo_sapiens	ENSP00000356150	63.0612	45.3061	ictalurus_punctatus	ENSIPUP00000036509	66.0256	47.4359
ENSG00000198625	homo_sapiens	ENSP00000356150	62.6531	47.9592	esox_lucius	ENSELUP00000011515	59.9609	45.8984
ENSG00000198625	homo_sapiens	ENSP00000356150	13.6735	9.79592	electrophorus_electricus	ENSEEEP00000012727	69.0722	49.4845
ENSG00000198625	homo_sapiens	ENSP00000356150	60.4082	45.3061	electrophorus_electricus	ENSEEEP00000038953	66.5169	49.8876
ENSG00000198625	homo_sapiens	ENSP00000356150	17.3469	12.6531	electrophorus_electricus	ENSEEEP00000012726	72.0339	52.5424
ENSG00000198625	homo_sapiens	ENSP00000356150	63.4694	48.5714	oncorhynchus_kisutch	ENSOKIP00005034663	63.2114	48.374
ENSG00000198625	homo_sapiens	ENSP00000356150	63.4694	48.5714	oncorhynchus_mykiss	ENSOMYP00000063005	63.0832	48.2759
ENSG00000198625	homo_sapiens	ENSP00000356150	63.2653	48.5714	salmo_trutta	ENSSTUP00000012039	63.0081	48.374
ENSG00000198625	homo_sapiens	ENSP00000356150	58.3673	42.2449	gadus_morhua	ENSGMOP00000038642	39.3398	28.4732
ENSG00000198625	homo_sapiens	ENSP00000356150	10	5.91837	gadus_morhua	ENSGMOP00000018452	56.3218	33.3333
ENSG00000198625	homo_sapiens	ENSP00000356150	61.8367	47.551	fundulus_heteroclitus	ENSFHEP00000019205	59.2955	45.5969
ENSG00000198625	homo_sapiens	ENSP00000356150	62.8571	47.9592	poecilia_reticulata	ENSPREP00000004787	62.8571	47.9592
ENSG00000198625	homo_sapiens	ENSP00000356150	62.6531	48.1633	xiphophorus_maculatus	ENSXMAP00000023343	62.6531	48.1633
ENSG00000198625	homo_sapiens	ENSP00000356150	62.449	47.3469	oryzias_latipes	ENSORLP00000035882	62.3218	47.2505
ENSG00000198625	homo_sapiens	ENSP00000356150	62.449	48.5714	cyclopterus_lumpus	ENSCLMP00005015912	61.5694	47.8873
ENSG00000198625	homo_sapiens	ENSP00000356150	62.449	48.9796	oreochromis_niloticus	ENSONIP00000024311	59.7656	46.875
ENSG00000198625	homo_sapiens	ENSP00000356150	62.6531	48.7755	haplochromis_burtoni	ENSHBUP00000024857	62.0202	48.2828
ENSG00000198625	homo_sapiens	ENSP00000356150	62.6531	48.7755	astatotilapia_calliptera	ENSACLP00000009363	62.0202	48.2828
ENSG00000198625	homo_sapiens	ENSP00000356150	62.2449	47.9592	sparus_aurata	ENSSAUP00010024235	59.4542	45.809
ENSG00000198625	homo_sapiens	ENSP00000356150	62.8571	49.3878	lates_calcarifer	ENSLCAP00010025636	62.0968	48.7903
ENSG00000198625	homo_sapiens	ENSP00000356150	62.8571	47.1429	xenopus_tropicalis	ENSXETP00000000049	63.5052	47.6289
ENSG00000198625	homo_sapiens	ENSP00000356150	74.898	63.0612	chrysemys_picta_bellii	ENSCPBP00000001475	76.9392	64.7799
ENSG00000198625	homo_sapiens	ENSP00000356150	20.6122	15.5102	sphenodon_punctatus	ENSSPUP00000015944	72.1429	54.2857
ENSG00000198625	homo_sapiens	ENSP00000356150	51.6327	41.8367	sphenodon_punctatus	ENSSPUP00000015896	72.9107	59.0778
ENSG00000198625	homo_sapiens	ENSP00000356150	28.9796	21.0204	crocodylus_porosus	ENSCPRP00005015052	43.4251	31.4985
ENSG00000198625	homo_sapiens	ENSP00000356150	15.3061	12.449	crocodylus_porosus	ENSCPRP00005015059	79.7872	64.8936
ENSG00000198625	homo_sapiens	ENSP00000356150	13.6735	9.18367	crocodylus_porosus	ENSCPRP00005015055	72.8261	48.913
ENSG00000198625	homo_sapiens	ENSP00000356150	62.8571	49.3878	laticauda_laticaudata	ENSLLTP00000020748	72.4706	56.9412
ENSG00000198625	homo_sapiens	ENSP00000356150	70.2041	55.7143	notechis_scutatus	ENSNSUP00000022752	72.4211	57.4737
ENSG00000198625	homo_sapiens	ENSP00000356150	12.8571	9.79592	pseudonaja_textilis	ENSPTXP00000019289	76.8293	58.5366
ENSG00000198625	homo_sapiens	ENSP00000356150	19.1837	15.3061	pseudonaja_textilis	ENSPTXP00000019286	74.6032	59.5238
ENSG00000198625	homo_sapiens	ENSP00000356150	75.7143	62.0408	anas_platyrhynchos_platyrhynchos	ENSAPLP00000012492	78.1053	64
ENSG00000198625	homo_sapiens	ENSP00000356150	74.898	61.2245	gallus_gallus	ENSGALP00010040278	66.8488	54.6448
ENSG00000198625	homo_sapiens	ENSP00000356150	25.102	20.4082	meleagris_gallopavo	ENSMGAP00000027383	71.0983	57.8035
ENSG00000198625	homo_sapiens	ENSP00000356150	74.898	62.0408	meleagris_gallopavo	ENSMGAP00000022040	70.3065	58.2375
ENSG00000198625	homo_sapiens	ENSP00000356150	70.6122	55.3061	serinus_canaria	ENSSCAP00000009337	73.617	57.6596
ENSG00000198625	homo_sapiens	ENSP00000356150	66.3265	50.4082	parus_major	ENSPMJP00000023016	59.633	45.3211
ENSG00000198625	homo_sapiens	ENSP00000356150	71.8367	55.9184	anolis_carolinensis	ENSACAP00000007244	74.4186	57.9281
ENSG00000198625	homo_sapiens	ENSP00000356150	60.8163	47.1429	neolamprologus_brichardi	ENSNBRP00000016450	63.0021	48.8372
ENSG00000198625	homo_sapiens	ENSP00000356150	69.3878	55.3061	naja_naja	ENSNNAP00000004149	72.0339	57.4153
ENSG00000198625	homo_sapiens	ENSP00000356150	70.4082	55.3061	podarcis_muralis	ENSPMRP00000022178	73.5608	57.7825
ENSG00000198625	homo_sapiens	ENSP00000356150	71.0204	57.1429	geospiza_fortis	ENSGFOP00000015324	74.0426	59.5745
ENSG00000198625	homo_sapiens	ENSP00000356150	70.4082	54.898	taeniopygia_guttata	ENSTGUP00000023572	73.2484	57.1125
ENSG00000198625	homo_sapiens	ENSP00000356150	62.6531	46.1224	erpetoichthys_calabaricus	ENSECRP00000007716	63.8254	46.9854
ENSG00000198625	homo_sapiens	ENSP00000356150	63.4694	48.1633	kryptolebias_marmoratus	ENSKMAP00000018825	63.4694	48.1633
ENSG00000198625	homo_sapiens	ENSP00000356150	72.0408	56.7347	salvator_merianae	ENSSMRP00000003930	74.1597	58.4034
ENSG00000198625	homo_sapiens	ENSP00000356150	63.0612	48.1633	oryzias_javanicus	ENSOJAP00000030780	62.9328	48.0652
ENSG00000198625	homo_sapiens	ENSP00000356150	23.4694	19.3878	amphilophus_citrinellus	ENSACIP00000000251	68.8623	56.8862
ENSG00000198625	homo_sapiens	ENSP00000356150	63.0612	49.3878	dicentrarchus_labrax	ENSDLAP00005047352	62.2984	48.7903
ENSG00000198625	homo_sapiens	ENSP00000356150	62.449	48.7755	amphiprion_percula	ENSAPEP00000009051	62.3218	48.6762
ENSG00000198625	homo_sapiens	ENSP00000356150	62.6531	47.1429	oryzias_sinensis	ENSOSIP00000013244	62.5255	47.0468
ENSG00000198625	homo_sapiens	ENSP00000356150	74.4898	62.449	pelodiscus_sinensis	ENSPSIP00000019027	77.167	64.6934
ENSG00000198625	homo_sapiens	ENSP00000356150	75.3061	63.2653	gopherus_evgoodei	ENSGEVP00005002148	77.3585	64.9895
ENSG00000198625	homo_sapiens	ENSP00000356150	75.5102	63.6735	chelonoidis_abingdonii	ENSCABP00000012804	77.4059	65.272
ENSG00000198625	homo_sapiens	ENSP00000356150	62.6531	49.1837	seriola_dumerili	ENSSDUP00000002400	61.8952	48.5887
ENSG00000198625	homo_sapiens	ENSP00000356150	62.8571	49.5918	cottoperca_gobio	ENSCGOP00000018454	62.0968	48.9919
ENSG00000198625	homo_sapiens	ENSP00000356150	74.898	61.6327	struthio_camelus_australis	ENSSCUP00000011808	70.5769	58.0769
ENSG00000198625	homo_sapiens	ENSP00000356150	75.3061	61.4286	anser_brachyrhynchus	ENSABRP00000013929	77.8481	63.5021
ENSG00000198625	homo_sapiens	ENSP00000356150	61.8367	46.7347	gasterosteus_aculeatus	ENSGACP00000000440	60.8434	45.9839
ENSG00000198625	homo_sapiens	ENSP00000356150	62.6531	48.7755	cynoglossus_semilaevis	ENSCSEP00000007236	62.0202	48.2828
ENSG00000198625	homo_sapiens	ENSP00000356150	62.8571	47.551	poecilia_formosa	ENSPFOP00000017382	62.8571	47.551
ENSG00000198625	homo_sapiens	ENSP00000356150	62.0408	48.5714	myripristis_murdjan	ENSMMDP00005000265	62.0408	48.5714
ENSG00000198625	homo_sapiens	ENSP00000356150	63.2653	49.7959	sander_lucioperca	ENSSLUP00000022123	62.5	49.1936
ENSG00000198625	homo_sapiens	ENSP00000356150	59.7959	46.1224	strigops_habroptila	ENSSHBP00005021823	70.7729	54.5894
ENSG00000198625	homo_sapiens	ENSP00000356150	21.6327	17.3469	strigops_habroptila	ENSSHBP00005021820	83.4646	66.9291
ENSG00000198625	homo_sapiens	ENSP00000356150	62.449	48.7755	amphiprion_ocellaris	ENSAOCP00000009207	62.3218	48.6762
ENSG00000198625	homo_sapiens	ENSP00000356150	16.9388	14.898	terrapene_carolina_triunguis	ENSTMTP00000011313	87.3684	76.8421
ENSG00000198625	homo_sapiens	ENSP00000356150	52.6531	43.8776	terrapene_carolina_triunguis	ENSTMTP00000011303	69.9187	58.2656
ENSG00000198625	homo_sapiens	ENSP00000356150	74.898	62.8571	terrapene_carolina_triunguis	ENSTMTP00000023710	76.9392	64.5702
ENSG00000198625	homo_sapiens	ENSP00000356150	63.0612	48.5714	hucho_hucho	ENSHHUP00000003676	62.173	47.8873
ENSG00000198625	homo_sapiens	ENSP00000356150	63.0612	49.1837	betta_splendens	ENSBSLP00000027363	61.8	48.2
ENSG00000198625	homo_sapiens	ENSP00000356150	64.4898	47.551	pygocentrus_nattereri	ENSPNAP00000026754	64.0974	47.2617
ENSG00000198625	homo_sapiens	ENSP00000356150	62.2449	48.9796	anabas_testudineus	ENSATEP00000043659	60.2767	47.4308
ENSG00000198625	homo_sapiens	ENSP00000356150	23.6735	11.8367	ciona_savignyi	ENSCSAVP00000019663	45.6693	22.8346
ENSG00000198625	homo_sapiens	ENSP00000356150	62.6531	49.1837	seriola_lalandi_dorsalis	ENSSLDP00000009280	61.8952	48.5887
ENSG00000198625	homo_sapiens	ENSP00000356150	15.9184	13.2653	seriola_lalandi_dorsalis	ENSSLDP00000012364	66.1017	55.0847
ENSG00000198625	homo_sapiens	ENSP00000356150	62.449	48.9796	labrus_bergylta	ENSLBEP00000015355	61.9433	48.583
ENSG00000198625	homo_sapiens	ENSP00000356150	62.6531	48.9796	pundamilia_nyererei	ENSPNYP00000023638	62.0202	48.4848
ENSG00000198625	homo_sapiens	ENSP00000356150	62.2449	48.9796	mastacembelus_armatus	ENSMAMP00000012442	61.4919	48.3871
ENSG00000198625	homo_sapiens	ENSP00000356150	62.6531	48.9796	stegastes_partitus	ENSSPAP00000012693	62.7812	49.0798
ENSG00000198625	homo_sapiens	ENSP00000356150	63.4694	48.5714	oncorhynchus_tshawytscha	ENSOTSP00005001308	63.0832	48.2759
ENSG00000198625	homo_sapiens	ENSP00000356150	62.6531	48.7755	acanthochromis_polyacanthus	ENSAPOP00000018645	61.6466	47.992
ENSG00000198625	homo_sapiens	ENSP00000356150	75.3061	61.0204	aquila_chrysaetos_chrysaetos	ENSACCP00020022740	77.8481	63.0802
ENSG00000198625	homo_sapiens	ENSP00000356150	62.6531	46.7347	nothobranchius_furzeri	ENSNFUP00015032334	62.5255	46.6395
ENSG00000198625	homo_sapiens	ENSP00000356150	60.4082	45.3061	cyprinodon_variegatus	ENSCVAP00000004343	64.488	48.366
ENSG00000198625	homo_sapiens	ENSP00000356150	64.2857	49.1837	denticeps_clupeoides	ENSDCDP00000037258	64.0244	48.9837
ENSG00000198625	homo_sapiens	ENSP00000356150	63.0612	49.1837	larimichthys_crocea	ENSLCRP00005014361	62.2984	48.5887
ENSG00000198625	homo_sapiens	ENSP00000356150	64.2857	49.3878	takifugu_rubripes	ENSTRUP00000002998	63.6364	48.8889
ENSG00000198625	homo_sapiens	ENSP00000356150	55.3061	43.8776	ficedula_albicollis	ENSFALP00000021644	63.1702	50.1166
ENSG00000198625	homo_sapiens	ENSP00000356150	11.6327	9.18367	ficedula_albicollis	ENSFALP00000023503	67.0588	52.9412
ENSG00000198625	homo_sapiens	ENSP00000356150	58.7755	44.898	hippocampus_comes	ENSHCOP00000007016	63.1579	48.2456
ENSG00000198625	homo_sapiens	ENSP00000356150	63.8776	47.7551	cyprinus_carpio_carpio	ENSCCRP00000029945	57.4312	42.9358
ENSG00000198625	homo_sapiens	ENSP00000356150	64.2857	49.5918	cyprinus_carpio_carpio	ENSCCRP00000170701	63.253	48.7952
ENSG00000198625	homo_sapiens	ENSP00000356150	70.4082	57.7551	coturnix_japonica	ENSCJPP00005011642	73.4043	60.2128
ENSG00000198625	homo_sapiens	ENSP00000356150	62.8571	47.551	poecilia_latipinna	ENSPLAP00000028092	62.8571	47.551
ENSG00000198625	homo_sapiens	ENSP00000356150	64.6939	48.5714	sinocyclocheilus_grahami	ENSSGRP00000091909	61.1969	45.9459
ENSG00000198625	homo_sapiens	ENSP00000356150	23.6735	18.7755	sinocyclocheilus_grahami	ENSSGRP00000101350	67.4419	53.4884
ENSG00000198625	homo_sapiens	ENSP00000356150	62.6531	48.7755	maylandia_zebra	ENSMZEP00005000406	60.9127	47.4206
ENSG00000198625	homo_sapiens	ENSP00000356150	63.2653	48.3673	tetraodon_nigroviridis	ENSTNIP00000010081	62.6263	47.8788
ENSG00000198625	homo_sapiens	ENSP00000356150	61.2245	46.5306	paramormyrops_kingsleyae	ENSPKIP00000031415	61.7284	46.9136
ENSG00000198625	homo_sapiens	ENSP00000356150	63.6735	47.3469	scleropages_formosus	ENSSFOP00015001657	62.7767	46.6801
ENSG00000198625	homo_sapiens	ENSP00000356150	64.898	50	leptobrachium_leishanense	ENSLLEP00000007151	67.2304	51.797
ENSG00000198625	homo_sapiens	ENSP00000356150	62.0408	47.3469	scophthalmus_maximus	ENSSMAP00000041686	59.4912	45.4012
ENSG00000198625	homo_sapiens	ENSP00000356150	63.2653	48.3673	oryzias_melastigma	ENSOMEP00000017594	63.1365	48.2688

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0000122	involved_in negative regulation of transcription by RNA polymerase II	1	IDA	Homo_sapiens(9606)	Process
GO:0003170	acts_upstream_of_or_within heart valve development	1	ISS	Homo_sapiens(9606)	Process
GO:0003181	acts_upstream_of_or_within atrioventricular valve morphogenesis	1	ISS	Homo_sapiens(9606)	Process
GO:0003203	acts_upstream_of_or_within endocardial cushion morphogenesis	1	ISS	Homo_sapiens(9606)	Process
GO:0003281	acts_upstream_of_or_within ventricular septum development	1	ISS	Homo_sapiens(9606)	Process
GO:0003283	acts_upstream_of_or_within atrial septum development	1	ISS	Homo_sapiens(9606)	Process
GO:0004842	enables ubiquitin-protein transferase activity	1	IBA	Homo_sapiens(9606)	Function
GO:0005515	enables protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0005634	located_in nucleus	1	NAS	Homo_sapiens(9606)	Component
GO:0005654	located_in nucleoplasm	2	IDA,TAS	Homo_sapiens(9606)	Component
GO:0008270	enables zinc ion binding	1	TAS	Homo_sapiens(9606)	Function
GO:0008285	involved_in negative regulation of cell population proliferation	1	TAS	Homo_sapiens(9606)	Process
GO:0016567	involved_in protein ubiquitination	1	IBA	Homo_sapiens(9606)	Process
GO:0017053	part_of transcription repressor complex	1	IPI	Homo_sapiens(9606)	Component
GO:0019899	enables enzyme binding	1	IPI	Homo_sapiens(9606)	Function
GO:0030330	involved_in DNA damage response, signal transduction by p53 class mediator	1	IEP	Homo_sapiens(9606)	Process
GO:0042177	involved_in negative regulation of protein catabolic process	1	IMP	Homo_sapiens(9606)	Process
GO:0043066	involved_in negative regulation of apoptotic process	1	IEA	Homo_sapiens(9606)	Process
GO:0045892	involved_in negative regulation of DNA-templated transcription	2	IDA,NAS	Homo_sapiens(9606)	Process
GO:0050821	involved_in protein stabilization	1	IEP	Homo_sapiens(9606)	Process
GO:0051726	involved_in regulation of cell cycle	1	IEA	Homo_sapiens(9606)	Process
GO:0065003	involved_in protein-containing complex assembly	1	IDA	Homo_sapiens(9606)	Process
GO:0071456	involved_in cellular response to hypoxia	1	IEP	Homo_sapiens(9606)	Process