RBP Type	Canonical_RBPs
Diseases	Disease
Drug	N.A.
Main interacting RNAs	N.A.
Moonlighting functions	TF
Localizations	N.A.
BulkPerturb-seq

Ensembl ID	ENSG00000197779	Gene ID	347344	Accession	13156
Symbol	ZNF81	Alias	HFZ20;MRX45;dJ54B20.6	Full Name	zinc finger protein 81
Status	Confidence	Length	165660 bases	Strand	Plus strand
Position	X : 47836902 - 48002561	RNA binding domain	zf-met
Summary	This gene encodes a protein that likely functions as a transcription factor. The protein contains an N-terminal KRAB domain and several C2H2-type zinc finger motifs. Mutations in this gene cause an X-linked form of intellectual disability (MRX45). Microduplication of a region of chromosome X including this gene has also been associated with other forms of intellectual disability. [provided by RefSeq, Jul 2017]

Protein	Domain	Pfam ID	E-value	Domain number
ENSP00000341151	zf-met	PF12874	5.8e-05	1
ENSP00000366153	zf-met	PF12874	5.8e-05	1

Pubmed ID	Full Name	Cell	Author	Time	Doi

Pubmed ID	Title	Author	Time	Journal

Name	Transcript ID	bp	Protein	Translation ID
ZNF81-202	ENST00000338637	11230	661aa	ENSP00000341151
ZNF81-204	ENST00000376954	11349	661aa	ENSP00000366153
ZNF81-201	ENST00000334937	610	69aa	ENSP00000334641
ZNF81-203	ENST00000376950	492	103aa	ENSP00000366149
ZNF81-205	ENST00000483520	475	No protein	-

Pathway ID	Pathway Name	Source

ensgID	Trait	pValue	Pubmed ID

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0000978	enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	1	IBA	Homo_sapiens(9606)	Function
GO:0000981	enables DNA-binding transcription factor activity, RNA polymerase II-specific	1	IBA	Homo_sapiens(9606)	Function
GO:0005634	is_active_in nucleus	1	IBA	Homo_sapiens(9606)	Component
GO:0006357	involved_in regulation of transcription by RNA polymerase II	1	IBA	Homo_sapiens(9606)	Process
GO:0046872	enables metal ion binding	1	IEA	Homo_sapiens(9606)	Function