Functions and Diseases

RBP Type Canonical_RBPs
Diseases SARS-COV-2DengueZika
Drug Drug
Main interacting RNAs rRNA
Moonlighting functions Metabolic enzymeTransmemebrane
Localizations N.A.
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000197756 Gene ID 6168 Accession 10348
Symbol RPL37A Alias L37A;eL43 Full Name ribosomal protein L37a
Status Confidence Length 80337 bases Strand Plus strand
Position 2 : 216498844 - 216579180 RNA binding domain Ribosomal_L37ae
Summary Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L37AE family of ribosomal proteins. It is located in the cytoplasm. The protein contains a C4-type zinc finger-like domain. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000418082 Ribosomal_L37ae PF01780 9.4e-46 1
ENSP00000388690 Ribosomal_L37ae PF01780 2e-38 1
ENSP00000470348 Ribosomal_L37ae PF01780 6.2e-38 1
ENSP00000410240 Ribosomal_L37ae PF01780 5.5e-32 1
ENSP00000469607 Ribosomal_L37ae PF01780 6.9e-25 1
ENSP00000471102 Ribosomal_L37ae PF01780 6.9e-25 1
ENSP00000472653 Ribosomal_L37ae PF01780 1.6e-24 1
ENSP00000410080 Ribosomal_L37ae PF01780 1.6e-21 1

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal

Transcripts

Name Transcript ID bp Protein Translation ID
RPL37A-207 ENST00000478153 2082 No protein -
RPL37A-209 ENST00000490649 1701 No protein -
RPL37A-208 ENST00000487233 2225 No protein -
RPL37A-210 ENST00000491306 2992 92aa ENSP00000418082
RPL37A-212 ENST00000600880 425 72aa ENSP00000470348
RPL37A-205 ENST00000446558 495 75aa ENSP00000388690
RPL37A-202 ENST00000420712 385 58aa ENSP00000410080
RPL37A-201 ENST00000359681 742 No protein -
RPL37A-206 ENST00000456586 401 68aa ENSP00000410240
RPL37A-203 ENST00000427280 698 88aa ENSP00000472653
RPL37A-211 ENST00000598925 775 60aa ENSP00000469607
RPL37A-204 ENST00000441179 529 60aa ENSP00000471102
RPL37A-213 ENST00000624436 559 No protein -

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
79581Diabetic Nephropathies7E-627647854
79582Renal Insufficiency, Chronic7E-627647854

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000197756

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000197756homo_sapiensENSP00000418082100100pongo_abeliiENSPPYP00000021078100100
ENSG00000197756homo_sapiensENSP0000041808298.91398.913sarcophilus_harrisiiENSSHAP0000004176980.53180.531
ENSG00000197756homo_sapiensENSP00000418082100100choloepus_hoffmanniENSCHOP00000003539100100
ENSG00000197756homo_sapiensENSP00000418082100100echinops_telfairiENSETEP00000011647100100
ENSG00000197756homo_sapiensENSP00000418082100100macaca_fascicularisENSMFAP00000060146100100
ENSG00000197756homo_sapiensENSP00000418082100100macaca_nemestrinaENSMNEP00000015558100100
ENSG00000197756homo_sapiensENSP00000418082100100mus_spretusMGP_SPRETEiJ_P0019224100100
ENSG00000197756homo_sapiensENSP00000418082100100equus_asinusENSEASP0000501821954.117654.1176
ENSG00000197756homo_sapiensENSP00000418082100100capra_hircusENSCHIP00000003737100100
ENSG00000197756homo_sapiensENSP00000418082100100panthera_leoENSPLOP00000029839100100
ENSG00000197756homo_sapiensENSP00000418082100100bos_indicus_hybridENSBIXP00005021577100100
ENSG00000197756homo_sapiensENSP00000418082100100oryctolagus_cuniculusENSOCUP00000046694100100
ENSG00000197756homo_sapiensENSP00000418082100100oryctolagus_cuniculusENSOCUP00000008528100100
ENSG00000197756homo_sapiensENSP00000418082100100equus_caballusENSECAP0000006740454.117654.1176
ENSG00000197756homo_sapiensENSP00000418082100100panthera_pardusENSPPRP00000022026100100
ENSG00000197756homo_sapiensENSP00000418082100100marmota_marmota_marmotaENSMMMP00000020338100100
ENSG00000197756homo_sapiensENSP00000418082100100balaenoptera_musculusENSBMSP00010005481100100
ENSG00000197756homo_sapiensENSP00000418082100100cavia_porcellusENSCPOP00000023224100100
ENSG00000197756homo_sapiensENSP00000418082100100monodelphis_domesticaENSMODP00000049610100100
ENSG00000197756homo_sapiensENSP00000418082100100bison_bison_bisonENSBBBP00000000631100100
ENSG00000197756homo_sapiensENSP00000418082100100monodon_monocerosENSMMNP00015009158100100
ENSG00000197756homo_sapiensENSP00000418082100100sus_scrofaENSSSCP00000045176100100
ENSG00000197756homo_sapiensENSP0000041808298.91398.913microcebus_murinusENSMICP0000003855294.791794.7917
ENSG00000197756homo_sapiensENSP00000418082100100octodon_degusENSODEP00000026648100100
ENSG00000197756homo_sapiensENSP00000418082100100ovis_aries_rambouilletENSOARP00020033064100100
ENSG00000197756homo_sapiensENSP00000418082100100ovis_aries_rambouilletENSOARP0002002905395.833395.8333
ENSG00000197756homo_sapiensENSP00000418082100100ursus_maritimusENSUMAP00000027758100100
ENSG00000197756homo_sapiensENSP00000418082100100ochotona_princepsENSOPRP00000004078100100
ENSG00000197756homo_sapiensENSP00000418082100100physeter_catodonENSPCTP00005024558100100
ENSG00000197756homo_sapiensENSP00000418082100100mus_caroliMGP_CAROLIEiJ_P0018216100100
ENSG00000197756homo_sapiensENSP00000418082100100mus_musculusENSMUSP00000058919100100
ENSG00000197756homo_sapiensENSP00000418082100100dipodomys_ordiiENSDORP00000020808100100
ENSG00000197756homo_sapiensENSP00000418082100100mustela_putorius_furoENSMPUP00000019509100100
ENSG00000197756homo_sapiensENSP0000041808296.739195.6522aotus_nancymaaeENSANAP0000000389297.802296.7033
ENSG00000197756homo_sapiensENSP00000418082100100saimiri_boliviensis_boliviensisENSSBOP00000032815100100
ENSG00000197756homo_sapiensENSP00000418082100100vicugna_pacosENSVPAP00000002332100100
ENSG00000197756homo_sapiensENSP00000418082100100tupaia_belangeriENSTBEP00000006390100100
ENSG00000197756homo_sapiensENSP00000418082100100mesocricetus_auratusENSMAUP00000022678100100
ENSG00000197756homo_sapiensENSP00000418082100100phocoena_sinusENSPSNP00000021080100100
ENSG00000197756homo_sapiensENSP00000418082100100camelus_dromedariusENSCDRP00005023605100100
ENSG00000197756homo_sapiensENSP00000418082100100panthera_tigris_altaicaENSPTIP00000026437100100
ENSG00000197756homo_sapiensENSP0000041808298.91398.913rattus_norvegicusENSRNOP0000009444874.590274.5902
ENSG00000197756homo_sapiensENSP0000041808298.91398.913prolemur_simusENSPSMP0000003520994.791794.7917
ENSG00000197756homo_sapiensENSP00000418082100100microtus_ochrogasterENSMOCP00000006889100100
ENSG00000197756homo_sapiensENSP00000418082100100peromyscus_maniculatus_bairdiiENSPEMP00000006330100100
ENSG00000197756homo_sapiensENSP00000418082100100bos_mutusENSBMUP00000034623100100
ENSG00000197756homo_sapiensENSP00000418082100100cricetulus_griseus_chok1gshdENSCGRP00001019187100100
ENSG00000197756homo_sapiensENSP0000041808298.91398.913pteropus_vampyrusENSPVAP00000005767100100
ENSG00000197756homo_sapiensENSP00000418082100100myotis_lucifugusENSMLUP00000016913100100
ENSG00000197756homo_sapiensENSP00000418082100100vombatus_ursinusENSVURP0001000352165.714365.7143
ENSG00000197756homo_sapiensENSP00000418082100100rhinolophus_ferrumequinumENSRFEP00010020195100100
ENSG00000197756homo_sapiensENSP00000418082100100bos_taurusENSBTAP00000060484100100
ENSG00000197756homo_sapiensENSP00000418082100100rhinopithecus_bietiENSRBIP00000011241100100
ENSG00000197756homo_sapiensENSP00000418082100100phascolarctos_cinereusENSPCIP00000021743100100
ENSG00000197756homo_sapiensENSP00000418082100100procavia_capensisENSPCAP00000006396100100
ENSG00000197756homo_sapiensENSP00000418082100100nannospalax_galiliENSNGAP00000009815100100
ENSG00000197756homo_sapiensENSP00000418082100100bos_grunniensENSBGRP00000003738100100
ENSG00000197756homo_sapiensENSP00000418082100100chinchilla_lanigeraENSCLAP00000022806100100
ENSG00000197756homo_sapiensENSP00000418082100100cervus_hanglu_yarkandensisENSCHYP0000000461190.196190.1961
ENSG00000197756homo_sapiensENSP00000418082100100catagonus_wagneriENSCWAP00000008452100100
ENSG00000197756homo_sapiensENSP00000418082100100ictidomys_tridecemlineatusENSSTOP00000030235100100
ENSG00000197756homo_sapiensENSP00000418082100100cebus_imitatorENSCCAP00000000306100100
ENSG00000197756homo_sapiensENSP00000418082100100cebus_imitatorENSCCAP00000002447100100
ENSG00000197756homo_sapiensENSP00000418082100100cebus_imitatorENSCCAP00000003430100100
ENSG00000197756homo_sapiensENSP00000418082100100cebus_imitatorENSCCAP00000007482100100
ENSG00000197756homo_sapiensENSP00000418082100100urocitellus_parryiiENSUPAP00010006628100100
ENSG00000197756homo_sapiensENSP00000418082100100moschus_moschiferusENSMMSP00000021053100100
ENSG00000197756homo_sapiensENSP00000418082100100mus_pahariMGP_PahariEiJ_P007352384.403784.4037
ENSG00000197756homo_sapiensENSP00000418082100100propithecus_coquereliENSPCOP00000003557100100
ENSG00000197756homo_sapiensENSP0000041808210097.8261petromyzon_marinusENSPMAP0000000000110097.8261
ENSG00000197756homo_sapiensENSP0000041808297.826189.1304eptatretus_burgeriENSEBUP0000000871273.770567.2131
ENSG00000197756homo_sapiensENSP0000041808297.826192.3913callorhinchus_miliiENSCMIP0000003838344.117641.6667
ENSG00000197756homo_sapiensENSP0000041808298.91397.8261latimeria_chalumnaeENSLACP0000001314698.91397.8261
ENSG00000197756homo_sapiensENSP0000041808298.91398.913gadus_morhuaENSGMOP0000004757098.91398.913
ENSG00000197756homo_sapiensENSP0000041808297.826197.8261fundulus_heteroclitusENSFHEP0000001694997.826197.8261
ENSG00000197756homo_sapiensENSP0000041808297.826197.8261poecilia_reticulataENSPREP0000003156595.744795.7447
ENSG00000197756homo_sapiensENSP0000041808298.91398.913xiphophorus_maculatusENSXMAP0000002252798.91398.913
ENSG00000197756homo_sapiensENSP0000041808296.739196.7391oryzias_latipesENSORLP0000001437098.888998.8889
ENSG00000197756homo_sapiensENSP0000041808272.826172.8261oreochromis_niloticusENSONIP0000003242598.529498.5294
ENSG00000197756homo_sapiensENSP0000041808296.739196.7391haplochromis_burtoniENSHBUP0000003475498.888998.8889
ENSG00000197756homo_sapiensENSP0000041808298.91398.913astatotilapia_callipteraENSACLP0000002655398.91398.913
ENSG00000197756homo_sapiensENSP0000041808294.565293.4783sparus_aurataENSSAUP0001006446594.565293.4783
ENSG00000197756homo_sapiensENSP0000041808298.91398.913neolamprologus_brichardiENSNBRP0000002077898.91398.913
ENSG00000197756homo_sapiensENSP0000041808298.91398.913oryzias_javanicusENSOJAP0000002773398.91398.913
ENSG00000197756homo_sapiensENSP0000041808297.826197.8261amphiprion_perculaENSAPEP0000003079260.402760.4027
ENSG00000197756homo_sapiensENSP0000041808298.91398.913oryzias_sinensisENSOSIP0000001419098.91398.913
ENSG00000197756homo_sapiensENSP0000041808297.826197.8261seriola_dumeriliENSSDUP0000000245098.901198.9011
ENSG00000197756homo_sapiensENSP0000041808298.91398.913cottoperca_gobioENSCGOP0000002548298.91398.913
ENSG00000197756homo_sapiensENSP0000041808298.91398.913gasterosteus_aculeatusENSGACP0000001650198.91398.913
ENSG00000197756homo_sapiensENSP0000041808297.826196.7391cynoglossus_semilaevisENSCSEP0000001373297.826196.7391
ENSG00000197756homo_sapiensENSP0000041808298.91398.913poecilia_formosaENSPFOP0000001468298.91398.913
ENSG00000197756homo_sapiensENSP0000041808210098.913myripristis_murdjanENSMMDP0000503186010098.913
ENSG00000197756homo_sapiensENSP0000041808298.91398.913sander_luciopercaENSSLUP0000000894598.91398.913
ENSG00000197756homo_sapiensENSP0000041808297.826197.8261amphiprion_ocellarisENSAOCP0000002385061.224561.2245
ENSG00000197756homo_sapiensENSP0000041808297.826195.6522betta_splendensENSBSLP0000005098897.826195.6522
ENSG00000197756homo_sapiensENSP0000041808272.826172.8261anabas_testudineusENSATEP0000005471098.529498.5294
ENSG00000197756homo_sapiensENSP0000041808298.91398.913seriola_lalandi_dorsalisENSSLDP0000000519598.91398.913
ENSG00000197756homo_sapiensENSP0000041808298.91398.913pundamilia_nyerereiENSPNYP0000002242698.91398.913
ENSG00000197756homo_sapiensENSP0000041808297.826197.8261mastacembelus_armatusENSMAMP0000004707256.2556.25
ENSG00000197756homo_sapiensENSP0000041808298.91398.913stegastes_partitusENSSPAP0000000431898.91398.913
ENSG00000197756homo_sapiensENSP0000041808272.826172.8261nothobranchius_furzeriENSNFUP0001502535898.529498.5294
ENSG00000197756homo_sapiensENSP0000041808297.826197.8261cyprinodon_variegatusENSCVAP0000001318597.826197.8261
ENSG00000197756homo_sapiensENSP0000041808297.826197.8261larimichthys_croceaENSLCRP0000503414097.826197.8261
ENSG00000197756homo_sapiensENSP0000041808298.91398.913poecilia_latipinnaENSPLAP0000001691898.91398.913
ENSG00000197756homo_sapiensENSP0000041808296.739196.7391maylandia_zebraENSMZEP0000501490298.888998.8889
ENSG00000197756homo_sapiensENSP0000041808298.91397.8261tetraodon_nigroviridisENSTNIP0000001073098.91397.8261
ENSG00000197756homo_sapiensENSP0000041808297.826197.8261scophthalmus_maximusENSSMAP0000002100994.736894.7368
ENSG00000197756homo_sapiensENSP0000041808298.91398.913oryzias_melastigmaENSOMEP0000002837598.91398.913

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0002181involved_in cytoplasmic translation2IC,NASHomo_sapiens(9606)Process
GO:0003723enables RNA binding1HDAHomo_sapiens(9606)Function
GO:0003735enables structural constituent of ribosome2IDA,NASHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005634located_in nucleus1HDAHomo_sapiens(9606)Component
GO:0005737located_in cytoplasm1NASHomo_sapiens(9606)Component
GO:0005829located_in cytosol1TASHomo_sapiens(9606)Component
GO:0005925located_in focal adhesion1HDAHomo_sapiens(9606)Component
GO:0006412involved_in translation1NASHomo_sapiens(9606)Process
GO:0022625part_of cytosolic large ribosomal subunit4HDA,IBA,IDA,IPIHomo_sapiens(9606)Component
GO:0022626located_in cytosolic ribosome1IDAHomo_sapiens(9606)Component
GO:0045202located_in synapse1IEAHomo_sapiens(9606)Component
GO:0046872enables metal ion binding1IEAHomo_sapiens(9606)Function
GO:0070062located_in extracellular exosome1HDAHomo_sapiens(9606)Component

Expression