RBP Type	Non-canonical_RBPs
Diseases	N.A.
Drug	Drug
Main interacting RNAs	N.A.
Moonlighting functions	N.A.
Localizations	N.A.
BulkPerturb-seq

Ensembl ID	ENSG00000196776	Gene ID	961	Accession	1682
Symbol	CD47	Alias	IAP;OA3;MER6	Full Name	CD47 molecule
Status	Confidence	Length	48772 bases	Strand	Minus strand
Position	3 : 108043091 - 108091862	RNA binding domain	N.A.
Summary	This gene encodes a membrane protein, which is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. The encoded protein is also a receptor for the C-terminal cell binding domain of thrombospondin, and it may play a role in membrane transport and signal transduction. This gene has broad tissue distribution, and is reduced in expression on Rh erythrocytes. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2010]

Protein	Domain	Pfam ID	E-value	Domain number

Pubmed ID	Full Name	Cell	Author	Time	Doi

Pubmed ID	Title	Author	Time	Journal
36889320	Detection and targeting of splicing deregulation in pediatric acute myeloid leukemia stem cells.	Inge I Werf van	2023-03-21	Cell reports. Medicine
26937127	Alternative polyadenylation can regulate post-translational membrane localization.	Mithun Mitra	2015-01-01	Trends in cell & molecular biology
31178900	Coding or Noncoding, the Converging Concepts of RNAs.	Jing Li	2019-01-01	Frontiers in genetics
31900325	3' UTRs Regulate Protein Functions by Providing a Nurturing Niche during Protein Synthesis.	Christine Mayr	2019-01-01	Cold Spring Harbor symposia on quantitative biology

Name	Transcript ID	bp	Protein	Translation ID
CD47-201	ENST00000355354	5228	305aa	ENSP00000347512
CD47-202	ENST00000361309	5292	323aa	ENSP00000355361
CD47-204	ENST00000471694	6796	No protein	-
CD47-203	ENST00000398258	469	86aa	ENSP00000381309
CD47-205	ENST00000517766	538	109aa	ENSP00000430843
CD47-206	ENST00000644850	766	183aa	ENSP00000493750

Pathway ID	Pathway Name	Source

ensgID	Trait	pValue	Pubmed ID
26759	Blood Pressure	2.6820000E-005	-
34590	Platelet Function Tests	2.0579000E-005	-
34602	Platelet Function Tests	3.2541600E-005	-
34603	Platelet Function Tests	3.1698000E-005	-
36933	Platelet Function Tests	5.0600000E-006	-
64806	Body Mass Index	5E-6	25673413
104220	Body Mass Index	2E-6	25673413

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0001525	involved_in angiogenesis	1	IEA	Homo_sapiens(9606)	Process
GO:0005515	enables protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0005886	located_in plasma membrane	1	TAS	Homo_sapiens(9606)	Component
GO:0006915	involved_in apoptotic process	1	IEA	Homo_sapiens(9606)	Process
GO:0006954	involved_in inflammatory response	1	IEA	Homo_sapiens(9606)	Process
GO:0007229	involved_in integrin-mediated signaling pathway	1	TAS	Homo_sapiens(9606)	Process
GO:0008284	involved_in positive regulation of cell population proliferation	1	IDA	Homo_sapiens(9606)	Process
GO:0009986	located_in cell surface	3	IDA,ISS,NAS	Homo_sapiens(9606)	Component
GO:0016477	involved_in cell migration	1	ISS	Homo_sapiens(9606)	Process
GO:0022409	involved_in positive regulation of cell-cell adhesion	2	IBA,IDA	Homo_sapiens(9606)	Process
GO:0032649	involved_in regulation of type II interferon production	1	IMP	Homo_sapiens(9606)	Process
GO:0032653	involved_in regulation of interleukin-10 production	1	IMP	Homo_sapiens(9606)	Process
GO:0032655	involved_in regulation of interleukin-12 production	1	IMP	Homo_sapiens(9606)	Process
GO:0032675	involved_in regulation of interleukin-6 production	1	IMP	Homo_sapiens(9606)	Process
GO:0032680	involved_in regulation of tumor necrosis factor production	1	IMP	Homo_sapiens(9606)	Process
GO:0034113	involved_in heterotypic cell-cell adhesion	1	IEA	Homo_sapiens(9606)	Process
GO:0035579	located_in specific granule membrane	1	TAS	Homo_sapiens(9606)	Component
GO:0045428	involved_in regulation of nitric oxide biosynthetic process	1	ISS	Homo_sapiens(9606)	Process
GO:0050729	involved_in positive regulation of inflammatory response	1	IBA	Homo_sapiens(9606)	Process
GO:0050766	involved_in positive regulation of phagocytosis	1	IBA	Homo_sapiens(9606)	Process
GO:0050870	involved_in positive regulation of T cell activation	1	IDA	Homo_sapiens(9606)	Process
GO:0051496	involved_in positive regulation of stress fiber assembly	1	ISS	Homo_sapiens(9606)	Process
GO:0070053	enables thrombospondin receptor activity	2	IBA,IPI	Homo_sapiens(9606)	Function
GO:0070062	is_active_in extracellular exosome	1	IBA	Homo_sapiens(9606)	Component
GO:0070821	located_in tertiary granule membrane	1	TAS	Homo_sapiens(9606)	Component
GO:0071346	involved_in cellular response to type II interferon	1	ISS	Homo_sapiens(9606)	Process
GO:0071347	involved_in cellular response to interleukin-1	1	ISS	Homo_sapiens(9606)	Process
GO:0071349	involved_in cellular response to interleukin-12	1	IMP	Homo_sapiens(9606)	Process
GO:0086080	enables protein binding involved in heterotypic cell-cell adhesion	1	ISS	Homo_sapiens(9606)	Function
GO:0098632	enables cell-cell adhesion mediator activity	1	IPI	Homo_sapiens(9606)	Function
GO:1904669	acts_upstream_of_or_within ATP export	1	IDA	Homo_sapiens(9606)	Process
GO:1905450	involved_in negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis	1	ISS	Homo_sapiens(9606)	Process
GO:2000439	involved_in positive regulation of monocyte extravasation	1	ISS	Homo_sapiens(9606)	Process