RBP Type
Canonical_RBPs
Diseases
Drug
N.A.
Main interacting RNAs
ncRNA
Moonlighting functions
N.A.
Localizations
N.A.
BulkPerturb-seq
N.A.
Ensembl ID ENSG00000186834 Gene ID
10614 Accession
24953
Symbol
HEXIM1
Alias
CLP1;EDG1;HIS1;MAQ1
Full Name
HEXIM P-TEFb complex subunit 1
Status
Confidence
Length
3625 bases
Strand
Plus strand
Position
17 : 45148475 - 45152099
RNA binding domain
HEXIM
Summary
Expression of this gene is induced by hexamethylene-bis-acetamide in vascular smooth muscle cells. This gene has no introns. [provided by RefSeq, Jul 2008]
RNA binding domains (RBDs)
Protein
Domain
Pfam ID
E-value
Domain number
ENSP00000328773
HEXIM
PF15313 1.2e-58
1
RNA binding proteomes (RBPomes)
Pubmed ID
Full Name
Cell
Author
Time
Doi
Literatures on RNA binding capacity
Pubmed ID
Title
Author
Time
Journal
17395637 HEXIM1 is a promiscuous double-stranded RNA-binding protein and interacts with RNAs in addition to 7SK in cultured cells.
Qintong Li
2007-01-01
Nucleic acids research
17925858 Cellular mRNA activates transcription elongation by displacing 7SK RNA.
M Tara Young
2007-10-10
PloS one
22609015 HEXIM1-binding elements on mRNAs identified through transcriptomic SELEX and computational screening.
Yuki Fujimoto
2012-09-01
Biochimie
36560640 Overexpression Bombyx mori HEXIM1 Facilitates Immune Escape of Bombyx mori Nucleopolyhedrovirus by Suppressing BmRelish-Driven Immune Responses.
Guanping Chen
2022-11-25
Viruses
25053825 BET protein antagonist JQ1 is synergistically lethal with FLT3 tyrosine kinase inhibitor (TKI) and overcomes resistance to FLT3-TKI in AML cells expressing FLT-ITD.
Warren Fiskus
2014-10-01
Molecular cancer therapeutics
15992410 Inhibition of Tat activity by the HEXIM1 protein.
Alessandro Fraldi
2005-07-02
Retrovirology
17709395 The transcription-dependent dissociation of P-TEFb-HEXIM1-7SK RNA relies upon formation of hnRNP-7SK RNA complexes.
Charlotte Barrandon
2007-10-01
Molecular and cellular biology
22821562 PKC phosphorylates HEXIM1 and regulates P-TEFb activity.
Koh Fujinaga
2012-10-01
Nucleic acids research
20808803 The mechanism of release of P-TEFb and HEXIM1 from the 7SK snRNP by viral and cellular activators includes a conformational change in 7SK.
J Brian Krueger
2010-08-23
PloS one
28082395 The crystal structure of the 5΄ functional domain of the transcription riboregulator 7SK.
Denise Martinez-Zapien
2017-04-07
Nucleic acids research
27058786 Stress from Nucleotide Depletion Activates the Transcriptional Regulator HEXIM1 to Suppress Melanoma.
L Justin Tan
2016-04-07
Molecular cell
20976203 Controlling cellular P-TEFb activity by the HIV-1 transcriptional transactivator Tat.
Lisa Muniz
2010-10-14
PLoS pathogens
23658523 Phosphorylation of CDK9 at Ser175 enhances HIV transcription and is a marker of activated P-TEFb in CD4(+) T lymphocytes.
R Uri Mbonye
2013-01-01
PLoS pathogens
28431135 Reconstitution of a functional 7SK snRNP.
E John Brogie
2017-06-20
Nucleic acids research
27852926 Solution structure of the 5'-terminal hairpin of the 7SK small nuclear RNA.
Sarah Bourbigot
2016-12-01
RNA (New York, N.Y.)
19244621 U30 of 7SK RNA forms a specific photo-cross-link with Hexim1 in the context of both a minimal RNA-binding site and a fully reconstituted 7SK/Hexim1/P-TEFb ribonucleoprotein complex.
François Bélanger
2009-03-06
Journal of molecular biology
23300697 Cardiomyocyte-specific overexpression of HEXIM1 prevents right ventricular hypertrophy in hypoxia-induced pulmonary hypertension in mice.
Noritada Yoshikawa
2012-01-01
PloS one
18281698 LARP7 is a stable component of the 7SK snRNP while P-TEFb, HEXIM1 and hnRNP A1 are reversibly associated.
J Brian Krueger
2008-04-01
Nucleic acids research
22379134 The Drosophila 7SK snRNP and the essential role of dHEXIM in development.
Duy Nguyen
2012-07-01
Nucleic acids research
Name
Transcript ID
bp
Protein
Translation ID
HEXIM1-201
ENST00000332499
3625
359aa
ENSP00000328773
Pathway ID
Pathway Name
Source
ensgID
Trait
pValue
Pubmed ID
ensgID SNP Chromosome Position
Trait PubmedID Or or BEAT
EFO ID
Protein-Protein Interaction (PPI)
Ensembl ID
Source
Target
Species
Protein ID
Perc_pos
Perc_id
Species
Protein ID
Perc_pos
Perc_id
ENSG00000186834 homo_sapiens ENSP00000466200 55.5944 44.0559 homo_sapiens ENSP00000328773 44.2897 35.0975
Ensembl ID
Source
Target
Species
Protein ID
Perc_pos
Perc_id
Species
Protein ID
Perc_pos
Perc_id
ENSG00000186834 homo_sapiens ENSP00000328773 99.7215 99.4429 nomascus_leucogenys ENSNLEP00000039672 99.7215 99.4429 ENSG00000186834 homo_sapiens ENSP00000328773 100 100 pan_paniscus ENSPPAP00000003263 100 100 ENSG00000186834 homo_sapiens ENSP00000328773 99.7215 99.4429 pongo_abelii ENSPPYP00000032217 99.7215 99.4429 ENSG00000186834 homo_sapiens ENSP00000328773 100 100 pan_troglodytes ENSPTRP00000069306 100 100 ENSG00000186834 homo_sapiens ENSP00000328773 99.7215 99.7215 gorilla_gorilla ENSGGOP00000014014 99.7215 99.7215 ENSG00000186834 homo_sapiens ENSP00000328773 62.6741 57.6602 ornithorhynchus_anatinus ENSOANP00000043498 81.5217 75 ENSG00000186834 homo_sapiens ENSP00000328773 76.8802 72.4234 sarcophilus_harrisii ENSSHAP00000034254 77.9661 73.4463 ENSG00000186834 homo_sapiens ENSP00000328773 87.1866 83.0084 dasypus_novemcinctus ENSDNOP00000020618 88.9205 84.6591 ENSG00000186834 homo_sapiens ENSP00000328773 59.0529 58.4958 erinaceus_europaeus ENSEEUP00000010563 98.1481 97.2222 ENSG00000186834 homo_sapiens ENSP00000328773 98.3287 97.7716 cercocebus_atys ENSCATP00000003966 98.3287 97.7716 ENSG00000186834 homo_sapiens ENSP00000328773 98.3287 98.0501 macaca_fascicularis ENSMFAP00000014621 98.3287 98.0501 ENSG00000186834 homo_sapiens ENSP00000328773 98.3287 98.0501 macaca_mulatta ENSMMUP00000069387 98.3287 98.0501 ENSG00000186834 homo_sapiens ENSP00000328773 98.3287 98.0501 macaca_nemestrina ENSMNEP00000000226 98.3287 98.0501 ENSG00000186834 homo_sapiens ENSP00000328773 98.3287 98.0501 papio_anubis ENSPANP00000010564 98.3287 98.0501 ENSG00000186834 homo_sapiens ENSP00000328773 98.3287 98.0501 mandrillus_leucophaeus ENSMLEP00000005728 98.3287 98.0501 ENSG00000186834 homo_sapiens ENSP00000328773 91.6435 90.2507 vulpes_vulpes ENSVVUP00000025000 91.6435 90.2507 ENSG00000186834 homo_sapiens ENSP00000328773 87.4652 84.6797 mus_spretus MGP_SPRETEiJ_P0031805 88.9518 86.119 ENSG00000186834 homo_sapiens ENSP00000328773 92.2006 90.8078 equus_asinus ENSEASP00005039676 91.9444 90.5556 ENSG00000186834 homo_sapiens ENSP00000328773 82.1727 80.7799 capra_hircus ENSCHIP00000001769 92.1875 90.625 ENSG00000186834 homo_sapiens ENSP00000328773 89.6936 87.4652 loxodonta_africana ENSLAFP00000016767 89.4444 87.2222 ENSG00000186834 homo_sapiens ENSP00000328773 91.922 90.2507 panthera_leo ENSPLOP00000011009 91.922 90.2507 ENSG00000186834 homo_sapiens ENSP00000328773 91.922 89.9721 ailuropoda_melanoleuca ENSAMEP00000020988 91.922 89.9721 ENSG00000186834 homo_sapiens ENSP00000328773 82.1727 80.2228 bos_indicus_hybrid ENSBIXP00005021555 92.1875 90 ENSG00000186834 homo_sapiens ENSP00000328773 92.2006 90.8078 equus_caballus ENSECAP00000000545 92.2006 90.8078 ENSG00000186834 homo_sapiens ENSP00000328773 91.922 90.2507 panthera_pardus ENSPPRP00000029199 91.922 90.2507 ENSG00000186834 homo_sapiens ENSP00000328773 90.5293 89.415 marmota_marmota_marmota ENSMMMP00000002782 91.5493 90.4225 ENSG00000186834 homo_sapiens ENSP00000328773 88.3008 86.9081 balaenoptera_musculus ENSBMSP00010024581 91.3545 89.9135 ENSG00000186834 homo_sapiens ENSP00000328773 55.7103 52.0891 cavia_porcellus ENSCPOP00000006431 91.7431 85.7798 ENSG00000186834 homo_sapiens ENSP00000328773 91.922 90.2507 felis_catus ENSFCAP00000005078 91.922 90.2507 ENSG00000186834 homo_sapiens ENSP00000328773 66.0167 65.4596 ursus_americanus ENSUAMP00000031349 95.9514 95.1417 ENSG00000186834 homo_sapiens ENSP00000328773 76.0446 71.5877 monodelphis_domestica ENSMODP00000032616 77.3371 72.8045 ENSG00000186834 homo_sapiens ENSP00000328773 63.5098 62.3955 bison_bison_bison ENSBBBP00000024650 94.2149 92.562 ENSG00000186834 homo_sapiens ENSP00000328773 88.0223 86.6295 monodon_monoceros ENSMMNP00015024249 91.0663 89.6254 ENSG00000186834 homo_sapiens ENSP00000328773 88.3008 86.9081 sus_scrofa ENSSSCP00000069849 91.092 89.6552 ENSG00000186834 homo_sapiens ENSP00000328773 56.2674 52.6462 octodon_degus ENSODEP00000024727 92.6606 86.6973 ENSG00000186834 homo_sapiens ENSP00000328773 88.8579 86.9081 jaculus_jaculus ENSJJAP00000003175 88.8579 86.9081 ENSG00000186834 homo_sapiens ENSP00000328773 63.5098 62.117 ovis_aries_rambouillet ENSOARP00020033311 94.2149 92.1488 ENSG00000186834 homo_sapiens ENSP00000328773 66.0167 65.4596 ursus_maritimus ENSUMAP00000019784 95.9514 95.1417 ENSG00000186834 homo_sapiens ENSP00000328773 88.3008 86.9081 delphinapterus_leucas ENSDLEP00000009006 91.3545 89.9135 ENSG00000186834 homo_sapiens ENSP00000328773 88.0223 86.351 physeter_catodon ENSPCTP00005019904 91.0663 89.3372 ENSG00000186834 homo_sapiens ENSP00000328773 87.7437 84.9582 mus_caroli MGP_CAROLIEiJ_P0030364 89.2351 86.4023 ENSG00000186834 homo_sapiens ENSP00000328773 88.0223 84.9582 mus_musculus ENSMUSP00000057339 88.764 85.6742 ENSG00000186834 homo_sapiens ENSP00000328773 89.9721 87.4652 dipodomys_ordii ENSDORP00000013858 90.9859 88.4507 ENSG00000186834 homo_sapiens ENSP00000328773 92.7577 90.8078 mustela_putorius_furo ENSMPUP00000018922 92.7577 90.8078 ENSG00000186834 homo_sapiens ENSP00000328773 98.3287 97.7716 aotus_nancymaae ENSANAP00000001451 98.3287 97.7716 ENSG00000186834 homo_sapiens ENSP00000328773 97.7716 96.9359 saimiri_boliviensis_boliviensis ENSSBOP00000003471 97.7716 96.9359 ENSG00000186834 homo_sapiens ENSP00000328773 98.0501 97.7716 chlorocebus_sabaeus ENSCSAP00000018531 98.324 98.0447 ENSG00000186834 homo_sapiens ENSP00000328773 64.9025 63.5098 mesocricetus_auratus ENSMAUP00000020499 94.7154 92.6829 ENSG00000186834 homo_sapiens ENSP00000328773 88.3008 86.9081 phocoena_sinus ENSPSNP00000027882 91.3545 89.9135 ENSG00000186834 homo_sapiens ENSP00000328773 89.6936 87.1866 camelus_dromedarius ENSCDRP00005006995 67.9325 66.0338 ENSG00000186834 homo_sapiens ENSP00000328773 71.0306 67.9666 carlito_syrichta ENSTSYP00000025802 89.7887 85.9155 ENSG00000186834 homo_sapiens ENSP00000328773 91.922 90.2507 panthera_tigris_altaica ENSPTIP00000000446 91.922 90.2507 ENSG00000186834 homo_sapiens ENSP00000328773 87.7437 84.6797 rattus_norvegicus ENSRNOP00000004272 88.4831 85.3933 ENSG00000186834 homo_sapiens ENSP00000328773 91.3649 89.9721 prolemur_simus ENSPSMP00000021376 91.6201 90.2235 ENSG00000186834 homo_sapiens ENSP00000328773 65.1811 63.7883 microtus_ochrogaster ENSMOCP00000004785 95.1219 93.0894 ENSG00000186834 homo_sapiens ENSP00000328773 89.1365 86.9081 peromyscus_maniculatus_bairdii ENSPEMP00000001892 90.1408 87.8873 ENSG00000186834 homo_sapiens ENSP00000328773 63.5098 62.3955 bos_mutus ENSBMUP00000001977 94.2149 92.562 ENSG00000186834 homo_sapiens ENSP00000328773 88.3008 85.2368 mus_spicilegus ENSMSIP00000033116 89.0449 85.9551 ENSG00000186834 homo_sapiens ENSP00000328773 88.3008 84.9582 cricetulus_griseus_chok1gshd ENSCGRP00001002169 89.0449 85.6742 ENSG00000186834 homo_sapiens ENSP00000328773 90.8078 86.9081 myotis_lucifugus ENSMLUP00000005068 90.8078 86.9081 ENSG00000186834 homo_sapiens ENSP00000328773 61.5599 58.7744 vombatus_ursinus ENSVURP00010011591 90.5738 86.4754 ENSG00000186834 homo_sapiens ENSP00000328773 91.0863 89.6936 rhinolophus_ferrumequinum ENSRFEP00010010312 91.3408 89.9441 ENSG00000186834 homo_sapiens ENSP00000328773 91.922 89.9721 neovison_vison ENSNVIP00000029566 91.922 89.9721 ENSG00000186834 homo_sapiens ENSP00000328773 82.1727 80.2228 bos_taurus ENSBTAP00000007955 92.1875 90 ENSG00000186834 homo_sapiens ENSP00000328773 56.2674 50.6964 heterocephalus_glaber_female ENSHGLP00000056618 68.7075 61.9048 ENSG00000186834 homo_sapiens ENSP00000328773 98.3287 98.3287 rhinopithecus_bieti ENSRBIP00000006802 98.3287 98.3287 ENSG00000186834 homo_sapiens ENSP00000328773 91.922 90.5293 canis_lupus_dingo ENSCAFP00020011817 91.922 90.5293 ENSG00000186834 homo_sapiens ENSP00000328773 92.7577 91.6435 sciurus_vulgaris ENSSVLP00005007116 93.5393 92.4157 ENSG00000186834 homo_sapiens ENSP00000328773 77.7159 72.9805 phascolarctos_cinereus ENSPCIP00000019748 78.1513 73.3894 ENSG00000186834 homo_sapiens ENSP00000328773 78.8301 76.0446 procavia_capensis ENSPCAP00000014745 80.6268 77.7778 ENSG00000186834 homo_sapiens ENSP00000328773 88.0223 84.9582 nannospalax_galili ENSNGAP00000003839 89.2655 86.1582 ENSG00000186834 homo_sapiens ENSP00000328773 63.5098 62.3955 bos_grunniens ENSBGRP00000038232 94.2149 92.562 ENSG00000186834 homo_sapiens ENSP00000328773 62.3955 61.0028 cervus_hanglu_yarkandensis ENSCHYP00000004053 92.1811 90.1235 ENSG00000186834 homo_sapiens ENSP00000328773 88.0223 86.6295 catagonus_wagneri ENSCWAP00000007583 90.8046 89.3678 ENSG00000186834 homo_sapiens ENSP00000328773 89.6936 88.5794 ictidomys_tridecemlineatus ENSSTOP00000014882 90.7042 89.5775 ENSG00000186834 homo_sapiens ENSP00000328773 91.0863 89.6936 otolemur_garnettii ENSOGAP00000008332 91.0863 89.6936 ENSG00000186834 homo_sapiens ENSP00000328773 97.7716 96.6574 cebus_imitator ENSCCAP00000003974 97.7716 96.6574 ENSG00000186834 homo_sapiens ENSP00000328773 89.6936 88.5794 urocitellus_parryii ENSUPAP00010001540 90.7042 89.5775 ENSG00000186834 homo_sapiens ENSP00000328773 59.3315 58.4958 moschus_moschiferus ENSMMSP00000028641 94.6667 93.3333 ENSG00000186834 homo_sapiens ENSP00000328773 98.0501 98.0501 rhinopithecus_roxellana ENSRROP00000003285 98.0501 98.0501 ENSG00000186834 homo_sapiens ENSP00000328773 87.7437 84.9582 mus_pahari MGP_PahariEiJ_P0037083 88.4831 85.6742 ENSG00000186834 homo_sapiens ENSP00000328773 30.9192 18.3844 drosophila_melanogaster FBpp0082427 30.8333 18.3333 ENSG00000186834 homo_sapiens ENSP00000328773 41.5042 31.7549 petromyzon_marinus ENSPMAP00000003796 68.3486 52.2936 ENSG00000186834 homo_sapiens ENSP00000328773 41.7827 29.805 eptatretus_burgeri ENSEBUP00000019136 51.7241 36.8966 ENSG00000186834 homo_sapiens ENSP00000328773 48.1894 39.8329 callorhinchus_milii ENSCMIP00000015179 54.5741 45.1104 ENSG00000186834 homo_sapiens ENSP00000328773 42.8969 32.312 latimeria_chalumnae ENSLACP00000004117 70.3196 52.968 ENSG00000186834 homo_sapiens ENSP00000328773 47.0752 40.6685 latimeria_chalumnae ENSLACP00000003733 86.2245 74.4898 ENSG00000186834 homo_sapiens ENSP00000328773 55.4318 44.8468 lepisosteus_oculatus ENSLOCP00000021616 59.2262 47.9167 ENSG00000186834 homo_sapiens ENSP00000328773 56.546 42.3398 clupea_harengus ENSCHAP00000041753 58.1662 43.553 ENSG00000186834 homo_sapiens ENSP00000328773 52.3677 41.2256 danio_rerio ENSDARP00000053002 58.9342 46.395 ENSG00000186834 homo_sapiens ENSP00000328773 52.9248 42.8969 carassius_auratus ENSCARP00000102772 43.7788 35.4839 ENSG00000186834 homo_sapiens ENSP00000328773 50.6964 40.39 astyanax_mexicanus ENSAMXP00000028030 46.076 36.7089 ENSG00000186834 homo_sapiens ENSP00000328773 52.9248 41.5042 ictalurus_punctatus ENSIPUP00000006216 55.2326 43.314 ENSG00000186834 homo_sapiens ENSP00000328773 48.1894 39.5543 electrophorus_electricus ENSEEEP00000031937 49.8559 40.9222 ENSG00000186834 homo_sapiens ENSP00000328773 48.7465 36.2117 electrophorus_electricus ENSEEEP00000027985 51.1696 38.0117 ENSG00000186834 homo_sapiens ENSP00000328773 55.9889 42.8969 oncorhynchus_kisutch ENSOKIP00005020381 50.6297 38.7909 ENSG00000186834 homo_sapiens ENSP00000328773 55.7103 42.8969 oncorhynchus_mykiss ENSOMYP00000071759 50.3778 38.7909 ENSG00000186834 homo_sapiens ENSP00000328773 56.546 44.5682 oncorhynchus_mykiss ENSOMYP00000024489 53.9894 42.5532 ENSG00000186834 homo_sapiens ENSP00000328773 56.8245 44.8468 salmo_salar ENSSSAP00000085234 54.4 42.9333 ENSG00000186834 homo_sapiens ENSP00000328773 56.8245 44.0111 salmo_salar ENSSSAP00000180796 54.2553 42.0213 ENSG00000186834 homo_sapiens ENSP00000328773 56.8245 44.8468 salmo_trutta ENSSTUP00000006559 54.4 42.9333 ENSG00000186834 homo_sapiens ENSP00000328773 56.546 43.7326 salmo_trutta ENSSTUP00000057317 45.7207 35.3604 ENSG00000186834 homo_sapiens ENSP00000328773 55.4318 43.454 gadus_morhua ENSGMOP00000035320 53.4946 41.9355 ENSG00000186834 homo_sapiens ENSP00000328773 53.2033 40.39 fundulus_heteroclitus ENSFHEP00000027711 60.2524 45.7413 ENSG00000186834 homo_sapiens ENSP00000328773 55.4318 42.0613 poecilia_reticulata ENSPREP00000013159 54.2234 41.1444 ENSG00000186834 homo_sapiens ENSP00000328773 55.9889 41.5042 xiphophorus_maculatus ENSXMAP00000008441 54.7684 40.5995 ENSG00000186834 homo_sapiens ENSP00000328773 56.8245 40.6685 oryzias_latipes ENSORLP00000031228 56.1983 40.2204 ENSG00000186834 homo_sapiens ENSP00000328773 53.4819 40.6685 cyclopterus_lumpus ENSCLMP00005023262 54.0845 41.1268 ENSG00000186834 homo_sapiens ENSP00000328773 55.4318 41.2256 oreochromis_niloticus ENSONIP00000026232 55.1247 40.9972 ENSG00000186834 homo_sapiens ENSP00000328773 55.1532 41.2256 haplochromis_burtoni ENSHBUP00000025473 55.1532 41.2256 ENSG00000186834 homo_sapiens ENSP00000328773 55.1532 41.2256 astatotilapia_calliptera ENSACLP00000000874 55.1532 41.2256 ENSG00000186834 homo_sapiens ENSP00000328773 54.8747 41.5042 sparus_aurata ENSSAUP00010032835 54.4199 41.1602 ENSG00000186834 homo_sapiens ENSP00000328773 55.1532 42.0613 lates_calcarifer ENSLCAP00010050959 52.6596 40.1596 ENSG00000186834 homo_sapiens ENSP00000328773 51.2535 40.9471 xenopus_tropicalis ENSXETP00000118015 62.585 50 ENSG00000186834 homo_sapiens ENSP00000328773 60.7242 55.7103 chrysemys_picta_bellii ENSCPBP00000011646 88.6179 81.3008 ENSG00000186834 homo_sapiens ENSP00000328773 69.6379 61.5599 sphenodon_punctatus ENSSPUP00000013707 73.5294 65 ENSG00000186834 homo_sapiens ENSP00000328773 58.7744 53.7604 crocodylus_porosus ENSCPRP00005022231 85.0806 77.8226 ENSG00000186834 homo_sapiens ENSP00000328773 56.2674 48.1894 laticauda_laticaudata ENSLLTP00000010275 84.5188 72.3849 ENSG00000186834 homo_sapiens ENSP00000328773 55.9889 48.1894 notechis_scutatus ENSNSUP00000021816 84.1004 72.3849 ENSG00000186834 homo_sapiens ENSP00000328773 55.9889 48.1894 pseudonaja_textilis ENSPTXP00000013386 83.75 72.0833 ENSG00000186834 homo_sapiens ENSP00000328773 54.8747 49.5822 anas_platyrhynchos_platyrhynchos ENSAPLP00000007564 89.5455 80.9091 ENSG00000186834 homo_sapiens ENSP00000328773 52.0891 46.5181 gallus_gallus ENSGALP00010035334 73.3333 65.4902 ENSG00000186834 homo_sapiens ENSP00000328773 60.4457 52.6462 meleagris_gallopavo ENSMGAP00000032185 50.348 43.8515 ENSG00000186834 homo_sapiens ENSP00000328773 61.5599 54.039 parus_major ENSPMJP00000003929 68 59.6923 ENSG00000186834 homo_sapiens ENSP00000328773 63.7883 56.2674 anolis_carolinensis ENSACAP00000016029 67.7515 59.7633 ENSG00000186834 homo_sapiens ENSP00000328773 55.1532 41.2256 neolamprologus_brichardi ENSNBRP00000026822 55.1532 41.2256 ENSG00000186834 homo_sapiens ENSP00000328773 50.4178 42.0613 naja_naja ENSNNAP00000018557 63.5088 52.9825 ENSG00000186834 homo_sapiens ENSP00000328773 61.8384 52.0891 naja_naja ENSNNAP00000012278 59.2 49.8667 ENSG00000186834 homo_sapiens ENSP00000328773 65.4596 56.2674 podarcis_muralis ENSPMRP00000016319 66.0112 56.7416 ENSG00000186834 homo_sapiens ENSP00000328773 58.4958 51.532 taeniopygia_guttata ENSTGUP00000031244 72.6644 64.0138 ENSG00000186834 homo_sapiens ENSP00000328773 51.8106 40.6685 erpetoichthys_calabaricus ENSECRP00000018428 54.0698 42.4419 ENSG00000186834 homo_sapiens ENSP00000328773 49.3036 41.7827 erpetoichthys_calabaricus ENSECRP00000018448 71.0843 60.241 ENSG00000186834 homo_sapiens ENSP00000328773 53.4819 42.3398 kryptolebias_marmoratus ENSKMAP00000014694 56.8047 44.9704 ENSG00000186834 homo_sapiens ENSP00000328773 62.117 54.3175 salvator_merianae ENSSMRP00000009339 69.2547 60.559 ENSG00000186834 homo_sapiens ENSP00000328773 55.4318 40.6685 oryzias_javanicus ENSOJAP00000020021 57.1839 41.954 ENSG00000186834 homo_sapiens ENSP00000328773 55.4318 40.6685 amphilophus_citrinellus ENSACIP00000011210 55.4318 40.6685 ENSG00000186834 homo_sapiens ENSP00000328773 54.8747 40.9471 dicentrarchus_labrax ENSDLAP00005078020 52.5333 39.2 ENSG00000186834 homo_sapiens ENSP00000328773 55.4318 42.0613 amphiprion_percula ENSAPEP00000003416 55.1247 41.8283 ENSG00000186834 homo_sapiens ENSP00000328773 56.546 40.39 oryzias_sinensis ENSOSIP00000003245 55.7692 39.8352 ENSG00000186834 homo_sapiens ENSP00000328773 55.4318 49.5822 pelodiscus_sinensis ENSPSIP00000010944 90.0452 80.543 ENSG00000186834 homo_sapiens ENSP00000328773 59.3315 55.1532 gopherus_evgoodei ENSGEVP00005027987 88.75 82.5 ENSG00000186834 homo_sapiens ENSP00000328773 59.3315 54.5961 chelonoidis_abingdonii ENSCABP00000006956 86.5854 79.6748 ENSG00000186834 homo_sapiens ENSP00000328773 38.9972 28.1337 seriola_dumerili ENSSDUP00000009098 45.4545 32.7922 ENSG00000186834 homo_sapiens ENSP00000328773 55.1532 41.7827 seriola_dumerili ENSSDUP00000031370 54.3956 41.2088 ENSG00000186834 homo_sapiens ENSP00000328773 49.0251 38.7187 cottoperca_gobio ENSCGOP00000050472 50.7205 40.0576 ENSG00000186834 homo_sapiens ENSP00000328773 62.3955 55.4318 anser_brachyrhynchus ENSABRP00000013704 75.6757 67.2297 ENSG00000186834 homo_sapiens ENSP00000328773 45.6825 35.9331 gasterosteus_aculeatus ENSGACP00000012408 65.0794 51.1905 ENSG00000186834 homo_sapiens ENSP00000328773 55.1532 41.2256 cynoglossus_semilaevis ENSCSEP00000015759 53.951 40.327 ENSG00000186834 homo_sapiens ENSP00000328773 55.4318 42.0613 poecilia_formosa ENSPFOP00000020208 54.0761 41.0326 ENSG00000186834 homo_sapiens ENSP00000328773 56.546 44.0111 myripristis_murdjan ENSMMDP00005032744 53.562 41.6887 ENSG00000186834 homo_sapiens ENSP00000328773 49.3036 37.0474 sander_lucioperca ENSSLUP00000026868 58.4158 43.8944 ENSG00000186834 homo_sapiens ENSP00000328773 62.3955 54.5961 strigops_habroptila ENSSHBP00005014451 74.4186 65.1163 ENSG00000186834 homo_sapiens ENSP00000328773 55.4318 42.0613 amphiprion_ocellaris ENSAOCP00000024112 55.1247 41.8283 ENSG00000186834 homo_sapiens ENSP00000328773 70.195 62.6741 terrapene_carolina_triunguis ENSTMTP00000023466 74.1176 66.1765 ENSG00000186834 homo_sapiens ENSP00000328773 57.1031 45.1253 hucho_hucho ENSHHUP00000062571 54.5213 43.0851 ENSG00000186834 homo_sapiens ENSP00000328773 56.8245 44.2897 hucho_hucho ENSHHUP00000071134 52.5773 40.9794 ENSG00000186834 homo_sapiens ENSP00000328773 54.8747 41.2256 betta_splendens ENSBSLP00000033289 52.957 39.7849 ENSG00000186834 homo_sapiens ENSP00000328773 51.532 40.6685 pygocentrus_nattereri ENSPNAP00000018766 56.7485 44.7853 ENSG00000186834 homo_sapiens ENSP00000328773 55.7103 40.9471 anabas_testudineus ENSATEP00000034077 54.4959 40.0545 ENSG00000186834 homo_sapiens ENSP00000328773 22.2841 17.5487 ciona_savignyi ENSCSAVP00000002023 53.3333 42 ENSG00000186834 homo_sapiens ENSP00000328773 38.9972 27.5766 seriola_lalandi_dorsalis ENSSLDP00000030887 43.4783 30.7453 ENSG00000186834 homo_sapiens ENSP00000328773 55.4318 41.7827 seriola_lalandi_dorsalis ENSSLDP00000000202 54.8209 41.3223 ENSG00000186834 homo_sapiens ENSP00000328773 54.3175 40.9471 labrus_bergylta ENSLBEP00000008624 53.5714 40.3846 ENSG00000186834 homo_sapiens ENSP00000328773 55.1532 40.9471 pundamilia_nyererei ENSPNYP00000016930 55.1532 40.9471 ENSG00000186834 homo_sapiens ENSP00000328773 55.4318 42.0613 mastacembelus_armatus ENSMAMP00000032781 54.2234 41.1444 ENSG00000186834 homo_sapiens ENSP00000328773 54.8747 42.0613 stegastes_partitus ENSSPAP00000004616 54.5706 41.8283 ENSG00000186834 homo_sapiens ENSP00000328773 55.9889 42.8969 oncorhynchus_tshawytscha ENSOTSP00005098045 50 38.3085 ENSG00000186834 homo_sapiens ENSP00000328773 56.8245 44.8468 oncorhynchus_tshawytscha ENSOTSP00005067904 54.2553 42.8191 ENSG00000186834 homo_sapiens ENSP00000328773 55.1532 42.0613 acanthochromis_polyacanthus ENSAPOP00000023724 54.6961 41.7127 ENSG00000186834 homo_sapiens ENSP00000328773 56.8245 49.0251 aquila_chrysaetos_chrysaetos ENSACCP00020023838 72.5979 62.6335 ENSG00000186834 homo_sapiens ENSP00000328773 51.2535 38.1616 nothobranchius_furzeri ENSNFUP00015005668 59.7403 44.4805 ENSG00000186834 homo_sapiens ENSP00000328773 54.5961 40.6685 cyprinodon_variegatus ENSCVAP00000010729 54.1436 40.3315 ENSG00000186834 homo_sapiens ENSP00000328773 43.454 36.2117 denticeps_clupeoides ENSDCDP00000015324 65.272 54.3933 ENSG00000186834 homo_sapiens ENSP00000328773 52.3677 42.6184 denticeps_clupeoides ENSDCDP00000010084 66.9039 54.4484 ENSG00000186834 homo_sapiens ENSP00000328773 50.6964 38.9972 larimichthys_crocea ENSLCRP00005018923 59.0909 45.4545 ENSG00000186834 homo_sapiens ENSP00000328773 54.039 40.6685 takifugu_rubripes ENSTRUP00000055381 53.0055 39.8907 ENSG00000186834 homo_sapiens ENSP00000328773 54.8747 48.7465 ficedula_albicollis ENSFALP00000026723 79.4355 70.5645 ENSG00000186834 homo_sapiens ENSP00000328773 47.3538 36.7688 hippocampus_comes ENSHCOP00000019327 60.0707 46.6431 ENSG00000186834 homo_sapiens ENSP00000328773 49.5822 40.39 cyprinus_carpio_carpio ENSCCRP00000168142 60.1351 48.9865 ENSG00000186834 homo_sapiens ENSP00000328773 53.4819 43.1755 cyprinus_carpio_carpio ENSCCRP00000156653 55.4913 44.7977 ENSG00000186834 homo_sapiens ENSP00000328773 58.4958 51.532 coturnix_japonica ENSCJPP00005024090 74.7331 65.8363 ENSG00000186834 homo_sapiens ENSP00000328773 55.4318 41.5042 poecilia_latipinna ENSPLAP00000001308 54.2234 40.5995 ENSG00000186834 homo_sapiens ENSP00000328773 52.9248 42.6184 sinocyclocheilus_grahami ENSSGRP00000075637 58.8235 47.3684 ENSG00000186834 homo_sapiens ENSP00000328773 52.3677 42.0613 sinocyclocheilus_grahami ENSSGRP00000019320 58.3851 46.8944 ENSG00000186834 homo_sapiens ENSP00000328773 55.1532 41.2256 maylandia_zebra ENSMZEP00005030829 55.1532 41.2256 ENSG00000186834 homo_sapiens ENSP00000328773 45.4039 34.8189 tetraodon_nigroviridis ENSTNIP00000000136 59.2727 45.4545 ENSG00000186834 homo_sapiens ENSP00000328773 57.3816 44.2897 paramormyrops_kingsleyae ENSPKIP00000005116 54.4974 42.0635 ENSG00000186834 homo_sapiens ENSP00000328773 55.4318 40.39 paramormyrops_kingsleyae ENSPKIP00000016773 55.4318 40.39 ENSG00000186834 homo_sapiens ENSP00000328773 56.546 43.1755 scleropages_formosus ENSSFOP00015039287 55.4645 42.3497 ENSG00000186834 homo_sapiens ENSP00000328773 51.532 42.3398 leptobrachium_leishanense ENSLLEP00000034817 63.3562 52.0548 ENSG00000186834 homo_sapiens ENSP00000328773 54.3175 41.7827 scophthalmus_maximus ENSSMAP00000017687 52.4194 40.3226 ENSG00000186834 homo_sapiens ENSP00000328773 56.2674 40.9471 oryzias_melastigma ENSOMEP00000019543 57.5499 41.8803
Go ID
Go term
No. evidence
Entries
Species
Category
GO:0000122 involved_in negative regulation of transcription by RNA polymerase II 3 IBA,IDA,IMP Homo_sapiens(9606) Process GO:0002218 involved_in activation of innate immune response 1 IDA Homo_sapiens(9606) Process GO:0004860 enables protein kinase inhibitor activity 1 IDA Homo_sapiens(9606) Function GO:0004861 enables cyclin-dependent protein serine/threonine kinase inhibitor activity 2 IBA,IDA Homo_sapiens(9606) Function GO:0005515 enables protein binding 1 IPI Homo_sapiens(9606) Function GO:0005634 located_in nucleus 1 IDA Homo_sapiens(9606) Component GO:0005654 is_active_in nucleoplasm 2 IBA,IDA Homo_sapiens(9606) Component GO:0005737 is_active_in cytoplasm 2 IBA,IDA Homo_sapiens(9606) Component GO:0007507 involved_in heart development 1 IEA Homo_sapiens(9606) Process GO:0017069 enables snRNA binding 1 IDA Homo_sapiens(9606) Function GO:0032897 involved_in negative regulation of viral transcription 1 IMP Homo_sapiens(9606) Process GO:0034244 involved_in negative regulation of transcription elongation by RNA polymerase II 1 IC Homo_sapiens(9606) Process GO:0042802 enables identical protein binding 1 IPI Homo_sapiens(9606) Function GO:0043231 located_in intracellular membrane-bounded organelle 1 IDA Homo_sapiens(9606) Component GO:0045087 involved_in innate immune response 1 IEA Homo_sapiens(9606) Process GO:0045736 involved_in negative regulation of cyclin-dependent protein serine/threonine kinase activity 2 IBA,IDA Homo_sapiens(9606) Process GO:0045892 involved_in negative regulation of DNA-templated transcription 1 IDA Homo_sapiens(9606) Process GO:0097322 enables 7SK snRNA binding 2 IBA,IDA Homo_sapiens(9606) Function GO:0106140 enables P-TEFb complex binding 1 IDA Homo_sapiens(9606) Function GO:0120259 part_of 7SK snRNP 1 IDA Homo_sapiens(9606) Component GO:1901798 involved_in positive regulation of signal transduction by p53 class mediator 1 IMP Homo_sapiens(9606) Process
Copyright © 2023, Bioinformatics Center, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, China. All Rights Reserved.
