RBPWorld - a comprehensive database of RNA Binding Proteins

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RBP World!

Functions and Diseases

RBP Type	Canonical_RBPs
Diseases	N.A.
Drug	N.A.
Main interacting RNAs	N.A.
Moonlighting functions	TF
Localizations	N.A.
BulkPerturb-seq

Description

Ensembl ID	ENSG00000185278	Gene ID	84614	Accession	28365
Symbol	ZBTB37	Alias	ZNF908;D430004I08Rik	Full Name	zinc finger and BTB domain containing 37
Status	Confidence	Length	35466 bases	Strand	Plus strand
Position	1 : 173868082 - 173903547	RNA binding domain	zf-met
Summary	Enables sequence-specific double-stranded DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be part of chromatin. Predicted to be active in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

RNA binding domains (RBDs)

Protein	Domain	Pfam ID	E-value	Domain number
ENSP00000356674	zf-met	PF12874	0.00063	1
ENSP00000511931	zf-met	PF12874	0.00063	1

RNA binding proteomes (RBPomes)

Pubmed ID	Full Name	Cell	Author	Time	Doi

Literatures on RNA binding capacity

Pubmed ID	Title	Author	Time	Journal

Transcripts

Name	Transcript ID	bp	Protein	Translation ID
ZBTB37-203	ENST00000367704	2323	308aa	ENSP00000356677
ZBTB37-201	ENST00000367701	19183	503aa	ENSP00000356674
ZBTB37-202	ENST00000367702	1337	361aa	ENSP00000356675
ZBTB37-204	ENST00000695459	3073	503aa	ENSP00000511931

Gene Model

Click here to download ENSG00000185278's gene model file

Pathways

Pathway ID	Pathway Name	Source

Phenotypes

ensgID	Trait	pValue	Pubmed ID
49903	Child Development Disorders, Pervasive	3.1138500E-005	-
69643	Emotions	9E-6	27089181

GWAS

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Protein-Protein Interaction (PPI)

Click here to download ENSG00000185278's PPI file

Paralogs

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Orthologs

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Gene Ontology

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0000122	involved_in negative regulation of transcription by RNA polymerase II	1	IBA	Homo_sapiens(9606)	Process
GO:0000785	part_of chromatin	1	ISA	Homo_sapiens(9606)	Component
GO:0000978	enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	1	IBA	Homo_sapiens(9606)	Function
GO:0000981	enables DNA-binding transcription factor activity, RNA polymerase II-specific	1	ISA	Homo_sapiens(9606)	Function
GO:0001227	enables DNA-binding transcription repressor activity, RNA polymerase II-specific	1	IBA	Homo_sapiens(9606)	Function
GO:0001817	involved_in regulation of cytokine production	1	IBA	Homo_sapiens(9606)	Process
GO:0002682	involved_in regulation of immune system process	1	IBA	Homo_sapiens(9606)	Process
GO:0005654	is_active_in nucleoplasm	1	IBA	Homo_sapiens(9606)	Component
GO:0046872	enables metal ion binding	1	IEA	Homo_sapiens(9606)	Function
GO:1990837	enables sequence-specific double-stranded DNA binding	1	IDA	Homo_sapiens(9606)	Function

Expression