Functions and Diseases

RBP Type Canonical_RBPs
Diseases Cancer
Drug N.A.
Main interacting RNAs rRNA
Moonlighting functions Metabolic enzyme
Localizations Nucleoli
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000185088 Gene ID 51065 Accession 18476
Symbol RPS27L Alias NA Full Name ribosomal protein S27 like
Status Confidence Length 9773 bases Strand Minus strand
Position 15 : 63148249 - 63158021 RNA binding domain Ribosomal_S27e
Summary This gene encodes a protein sharing 96% amino acid similarity with ribosomal protein S27, which suggests the encoded protein may be a component of the 40S ribosomal subunit. [provided by RefSeq, Jul 2008]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000331019 Ribosomal_S27e PF01667 8.2e-30 1
ENSP00000453764 Ribosomal_S27e PF01667 1.6e-29 1
ENSP00000402423 Ribosomal_S27e PF01667 7.5e-29 1
ENSP00000405300 Ribosomal_S27e PF01667 4.6e-26 1
ENSP00000412026 Ribosomal_S27e PF01667 4.6e-26 1
ENSP00000489261 Ribosomal_S27e PF01667 4.6e-26 1

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal

Transcripts

Name Transcript ID bp Protein Translation ID
RPS27L-207 ENST00000559763 244 No protein -
RPS27L-201 ENST00000330964 6110 84aa ENSP00000331019
RPS27L-205 ENST00000462430 681 100aa ENSP00000453764
RPS27L-204 ENST00000455271 923 52aa ENSP00000412026
RPS27L-206 ENST00000482846 2944 No protein -
RPS27L-208 ENST00000635699 693 52aa ENSP00000489261
RPS27L-202 ENST00000411926 528 52aa ENSP00000405300
RPS27L-203 ENST00000439025 970 97aa ENSP00000402423

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
80800Communication Disorders5E-624564958

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000185088homo_sapiensENSP0000049904498.809596.4286homo_sapiensENSP0000033101998.809596.4286

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000185088homo_sapiensENSP0000033101991.666791.6667nomascus_leucogenysENSNLEP0000002450680.208380.2083
ENSG00000185088homo_sapiensENSP0000033101990.476290.4762gorilla_gorillaENSGGOP0000002730879.166779.1667
ENSG00000185088homo_sapiensENSP0000033101992.857189.2857ornithorhynchus_anatinusENSOANP0000004831377.227774.2574
ENSG00000185088homo_sapiensENSP0000033101910097.619sarcophilus_harrisiiENSSHAP0000003157736.363635.4978
ENSG00000185088homo_sapiensENSP0000033101990.476286.9048notamacropus_eugeniiENSMEUP0000000899196.202592.4051
ENSG00000185088homo_sapiensENSP00000331019100100dasypus_novemcinctusENSDNOP0000002872076.363676.3636
ENSG00000185088homo_sapiensENSP0000033101991.666791.6667cercocebus_atysENSCATP0000000611279.381479.3814
ENSG00000185088homo_sapiensENSP0000033101998.809597.619macaca_fascicularisENSMFAP0000005382586.458385.4167
ENSG00000185088homo_sapiensENSP00000331019100100macaca_mulattaENSMMUP00000033519100100
ENSG00000185088homo_sapiensENSP00000331019100100macaca_nemestrinaENSMNEP00000019127100100
ENSG00000185088homo_sapiensENSP00000331019100100papio_anubisENSPANP00000027647100100
ENSG00000185088homo_sapiensENSP00000331019100100mandrillus_leucophaeusENSMLEP00000000440100100
ENSG00000185088homo_sapiensENSP0000033101992.857188.0952vulpes_vulpesENSVVUP0000001334181.2577.0833
ENSG00000185088homo_sapiensENSP0000033101989.285789.2857mus_spretusMGP_SPRETEiJ_P009207371.428671.4286
ENSG00000185088homo_sapiensENSP0000033101998.809598.8095equus_asinusENSEASP0000504106555.333355.3333
ENSG00000185088homo_sapiensENSP0000033101991.666790.4762capra_hircusENSCHIP0000001040093.902492.6829
ENSG00000185088homo_sapiensENSP0000033101998.809596.4286loxodonta_africanaENSLAFP0000001296798.809596.4286
ENSG00000185088homo_sapiensENSP0000033101991.666790.4762panthera_leoENSPLOP0000002129081.052680
ENSG00000185088homo_sapiensENSP0000033101990.476290.4762ailuropoda_melanoleucaENSAMEP0000000764562.809962.8099
ENSG00000185088homo_sapiensENSP0000033101997.61996.4286bos_indicus_hybridENSBIXP0000501756980.392279.4118
ENSG00000185088homo_sapiensENSP00000331019100100oryctolagus_cuniculusENSOCUP00000040419100100
ENSG00000185088homo_sapiensENSP00000331019100100oryctolagus_cuniculusENSOCUP00000021589100100
ENSG00000185088homo_sapiensENSP00000331019100100oryctolagus_cuniculusENSOCUP00000045777100100
ENSG00000185088homo_sapiensENSP0000033101998.809598.8095equus_caballusENSECAP0000001095555.333355.3333
ENSG00000185088homo_sapiensENSP0000033101990.476288.0952canis_lupus_familiarisENSCAFP0084503979691.566389.1566
ENSG00000185088homo_sapiensENSP0000033101991.666790.4762panthera_pardusENSPPRP0000002743891.666790.4762
ENSG00000185088homo_sapiensENSP00000331019100100marmota_marmota_marmotaENSMMMP00000010700100100
ENSG00000185088homo_sapiensENSP00000331019100100balaenoptera_musculusENSBMSP00010000850100100
ENSG00000185088homo_sapiensENSP0000033101992.857191.6667cavia_porcellusENSCPOP0000001829092.857191.6667
ENSG00000185088homo_sapiensENSP00000331019100100felis_catusENSFCAP0000005084771.186471.1864
ENSG00000185088homo_sapiensENSP0000033101998.809597.619ursus_americanusENSUAMP0000002860292.222291.1111
ENSG00000185088homo_sapiensENSP0000033101910097.619monodelphis_domesticaENSMODP0000005344510097.619
ENSG00000185088homo_sapiensENSP0000033101997.61996.4286bison_bison_bisonENSBBBP0000002722380.392279.4118
ENSG00000185088homo_sapiensENSP0000033101994.047689.2857monodon_monocerosENSMMNP0001501902366.386663.0252
ENSG00000185088homo_sapiensENSP00000331019100100sus_scrofaENSSSCP00000026227100100
ENSG00000185088homo_sapiensENSP0000033101985.714383.3333microcebus_murinusENSMICP0000002625210097.2222
ENSG00000185088homo_sapiensENSP0000033101995.238192.8571octodon_degusENSODEP0000002692195.238192.8571
ENSG00000185088homo_sapiensENSP0000033101980.952480.9524jaculus_jaculusENSJJAP0000000418195.774795.7747
ENSG00000185088homo_sapiensENSP0000033101989.285789.2857jaculus_jaculusENSJJAP0000002117775.757675.7576
ENSG00000185088homo_sapiensENSP0000033101910098.8095ovis_aries_rambouilletENSOARP0002001120210098.8095
ENSG00000185088homo_sapiensENSP0000033101988.095285.7143ursus_maritimusENSUMAP0000003412847.435946.1538
ENSG00000185088homo_sapiensENSP0000033101989.285788.0952ochotona_princepsENSOPRP0000000804678.947477.8947
ENSG00000185088homo_sapiensENSP0000033101995.238192.8571delphinapterus_leucasENSDLEP0000001341294.117691.7647
ENSG00000185088homo_sapiensENSP0000033101989.285789.2857mus_musculusENSMUSP0000012051871.428671.4286
ENSG00000185088homo_sapiensENSP0000033101910098.8095dipodomys_ordiiENSDORP0000000710410098.8095
ENSG00000185088homo_sapiensENSP00000331019100100mustela_putorius_furoENSMPUP00000000641100100
ENSG00000185088homo_sapiensENSP0000033101995.238195.2381aotus_nancymaaeENSANAP0000000104095.238195.2381
ENSG00000185088homo_sapiensENSP0000033101992.857192.8571mesocricetus_auratusENSMAUP0000001437495.121995.1219
ENSG00000185088homo_sapiensENSP0000033101995.238189.2857phocoena_sinusENSPSNP0000000921086.021580.6452
ENSG00000185088homo_sapiensENSP0000033101996.428694.0476carlito_syrichtaENSTSYP0000002738986.170284.0426
ENSG00000185088homo_sapiensENSP0000033101997.61997.619carlito_syrichtaENSTSYP0000002474989.130489.1304
ENSG00000185088homo_sapiensENSP0000033101990.476289.2857panthera_tigris_altaicaENSPTIP0000000628490.476289.2857
ENSG00000185088homo_sapiensENSP0000033101990.476288.0952rattus_norvegicusENSRNOP0000008749364.957363.2479
ENSG00000185088homo_sapiensENSP0000033101995.238194.0476rattus_norvegicusENSRNOP0000008265171.428670.5357
ENSG00000185088homo_sapiensENSP0000033101910098.8095microtus_ochrogasterENSMOCP0000000096410098.8095
ENSG00000185088homo_sapiensENSP00000331019100100peromyscus_maniculatus_bairdiiENSPEMP00000025733100100
ENSG00000185088homo_sapiensENSP0000033101998.809597.619bos_mutusENSBMUP0000002280398.809597.619
ENSG00000185088homo_sapiensENSP0000033101997.61996.4286bos_mutusENSBMUP0000000433280.392279.4118
ENSG00000185088homo_sapiensENSP0000033101989.285789.2857mus_spicilegusENSMSIP0000000776996.153896.1538
ENSG00000185088homo_sapiensENSP0000033101994.047691.6667mus_spicilegusENSMSIP0000002650760.305358.7786
ENSG00000185088homo_sapiensENSP0000033101996.428694.0476cricetulus_griseus_chok1gshdENSCGRP0000101181596.428694.0476
ENSG00000185088homo_sapiensENSP0000033101998.809597.619myotis_lucifugusENSMLUP0000000762598.809597.619
ENSG00000185088homo_sapiensENSP0000033101910097.619vombatus_ursinusENSVURP0001002102544.919843.8503
ENSG00000185088homo_sapiensENSP0000033101988.095288.0952rhinolophus_ferrumequinumENSRFEP0001002187288.095288.0952
ENSG00000185088homo_sapiensENSP0000033101997.61997.619rhinolophus_ferrumequinumENSRFEP0001000632786.315886.3158
ENSG00000185088homo_sapiensENSP0000033101910098.8095bos_taurusENSBTAP0000001714610098.8095
ENSG00000185088homo_sapiensENSP0000033101996.428696.4286heterocephalus_glaber_femaleENSHGLP0000004299896.428696.4286
ENSG00000185088homo_sapiensENSP0000033101910098.8095heterocephalus_glaber_femaleENSHGLP0000001235773.043572.1739
ENSG00000185088homo_sapiensENSP00000331019100100rhinopithecus_bietiENSRBIP00000030726100100
ENSG00000185088homo_sapiensENSP0000033101990.476288.0952canis_lupus_dingoENSCAFP0002000119191.566389.1566
ENSG00000185088homo_sapiensENSP0000033101998.809598.8095sciurus_vulgarisENSSVLP0000502394467.479767.4797
ENSG00000185088homo_sapiensENSP0000033101998.809596.4286sciurus_vulgarisENSSVLP0000501367698.809596.4286
ENSG00000185088homo_sapiensENSP0000033101910097.619phascolarctos_cinereusENSPCIP0000004574347.19146.0674
ENSG00000185088homo_sapiensENSP00000331019100100nannospalax_galiliENSNGAP00000020737100100
ENSG00000185088homo_sapiensENSP0000033101997.61995.2381bos_grunniensENSBGRP0000000614731.782931.0078
ENSG00000185088homo_sapiensENSP00000331019100100chinchilla_lanigeraENSCLAP00000015730100100
ENSG00000185088homo_sapiensENSP0000033101995.238189.2857cervus_hanglu_yarkandensisENSCHYP0000000392082.474277.3196
ENSG00000185088homo_sapiensENSP0000033101991.666791.6667catagonus_wagneriENSCWAP0000000184282.795782.7957
ENSG00000185088homo_sapiensENSP0000033101990.476289.2857ictidomys_tridecemlineatusENSSTOP0000003170269.724868.8073
ENSG00000185088homo_sapiensENSP0000033101978.571478.5714cebus_imitatorENSCCAP0000001680197.058897.0588
ENSG00000185088homo_sapiensENSP00000331019100100urocitellus_parryiiENSUPAP00010025444100100
ENSG00000185088homo_sapiensENSP0000033101910097.619moschus_moschiferusENSMMSP0000002341170.588268.9076
ENSG00000185088homo_sapiensENSP00000331019100100rhinopithecus_roxellanaENSRROP00000018224100100
ENSG00000185088homo_sapiensENSP00000331019100100mus_pahariMGP_PahariEiJ_P0024086100100
ENSG00000185088homo_sapiensENSP0000033101991.666791.6667propithecus_coquereliENSPCOP0000001701581.914981.9149
ENSG00000185088homo_sapiensENSP0000033101998.809596.4286petromyzon_marinusENSPMAP0000000340898.809596.4286
ENSG00000185088homo_sapiensENSP0000033101959.523853.5714eptatretus_burgeriENSEBUP0000000781469.444462.5
ENSG00000185088homo_sapiensENSP0000033101997.61994.0476lepisosteus_oculatusENSLOCP0000001824310096.3415
ENSG00000185088homo_sapiensENSP0000033101995.238190.4762clupea_harengusENSCHAP0000001988078.431474.5098
ENSG00000185088homo_sapiensENSP0000033101997.61990.4762danio_rerioENSDARP0000014019097.61990.4762
ENSG00000185088homo_sapiensENSP0000033101996.428689.2857carassius_auratusENSCARP0000012547683.505277.3196
ENSG00000185088homo_sapiensENSP0000033101997.61990.4762carassius_auratusENSCARP0000013132660.740756.2963
ENSG00000185088homo_sapiensENSP0000033101996.428690.4762astyanax_mexicanusENSAMXP0000003864496.428690.4762
ENSG00000185088homo_sapiensENSP0000033101995.238189.2857electrophorus_electricusENSEEEP0000000127382.474277.3196
ENSG00000185088homo_sapiensENSP0000033101985.714378.5714gadus_morhuaENSGMOP000000143539082.5
ENSG00000185088homo_sapiensENSP0000033101995.238186.9048cyclopterus_lumpusENSCLMP0000500204593.023384.8837
ENSG00000185088homo_sapiensENSP0000033101994.047688.0952oreochromis_niloticusENSONIP0000004076884.946279.5699
ENSG00000185088homo_sapiensENSP0000033101989.285784.5238haplochromis_burtoniENSHBUP0000002977983.333378.8889
ENSG00000185088homo_sapiensENSP0000033101995.238190.4762astatotilapia_callipteraENSACLP0000002677895.238190.4762
ENSG00000185088homo_sapiensENSP0000033101992.857182.1429sparus_aurataENSSAUP0001001315382.978773.4043
ENSG00000185088homo_sapiensENSP0000033101989.285782.1429lates_calcariferENSLCAP0001002289588.235381.1765
ENSG00000185088homo_sapiensENSP0000033101997.61995.2381chrysemys_picta_belliiENSCPBP0000002502997.61995.2381
ENSG00000185088homo_sapiensENSP0000033101998.809597.619sphenodon_punctatusENSSPUP0000001996798.809597.619
ENSG00000185088homo_sapiensENSP0000033101910094.0476anas_platyrhynchos_platyrhynchosENSAPLP0000000310710094.0476
ENSG00000185088homo_sapiensENSP0000033101910096.4286gallus_gallusENSGALP0001003653610096.4286
ENSG00000185088homo_sapiensENSP0000033101910096.4286meleagris_gallopavoENSMGAP0000003244110096.4286
ENSG00000185088homo_sapiensENSP0000033101910095.2381serinus_canariaENSSCAP0000002283194.38289.8876
ENSG00000185088homo_sapiensENSP0000033101952.38152.381serinus_canariaENSSCAP0000000279191.666791.6667
ENSG00000185088homo_sapiensENSP0000033101910095.2381parus_majorENSPMJP0000000887610095.2381
ENSG00000185088homo_sapiensENSP0000033101990.476284.5238neolamprologus_brichardiENSNBRP0000002347284.444478.8889
ENSG00000185088homo_sapiensENSP0000033101986.904882.1429podarcis_muralisENSPMRP0000003551674.489870.4082
ENSG00000185088homo_sapiensENSP0000033101997.61992.8571geospiza_fortisENSGFOP0000001418610095.1219
ENSG00000185088homo_sapiensENSP0000033101910095.2381taeniopygia_guttataENSTGUP0000002934110095.2381
ENSG00000185088homo_sapiensENSP0000033101988.095279.7619amphilophus_citrinellusENSACIP0000000250676.288769.0722
ENSG00000185088homo_sapiensENSP0000033101992.857184.5238dicentrarchus_labraxENSDLAP0000507391564.462858.6777
ENSG00000185088homo_sapiensENSP0000033101989.285778.5714amphiprion_perculaENSAPEP0000002739780.645270.9677
ENSG00000185088homo_sapiensENSP0000033101997.61995.2381gopherus_evgoodeiENSGEVP0000502508397.61995.2381
ENSG00000185088homo_sapiensENSP0000033101997.61995.2381chelonoidis_abingdoniiENSCABP0000000523197.61995.2381
ENSG00000185088homo_sapiensENSP0000033101994.047684.5238seriola_dumeriliENSSDUP0000001281488.76479.7753
ENSG00000185088homo_sapiensENSP0000033101994.047688.0952cottoperca_gobioENSCGOP0000001147594.047688.0952
ENSG00000185088homo_sapiensENSP0000033101910095.2381anser_brachyrhynchusENSABRP0000001096710095.2381
ENSG00000185088homo_sapiensENSP0000033101998.809595.2381gasterosteus_aculeatusENSGACP0000001579398.809595.2381
ENSG00000185088homo_sapiensENSP0000033101990.476279.7619cynoglossus_semilaevisENSCSEP0000000381669.724861.4679
ENSG00000185088homo_sapiensENSP0000033101995.238188.0952myripristis_murdjanENSMMDP0000502569360.606156.0606
ENSG00000185088homo_sapiensENSP0000033101994.047688.0952sander_luciopercaENSSLUP0000003495859.398555.6391
ENSG00000185088homo_sapiensENSP0000033101996.428690.4762strigops_habroptilaENSSHBP0000502070164.285760.3175
ENSG00000185088homo_sapiensENSP0000033101989.285779.7619amphiprion_ocellarisENSAOCP0000002107480.645272.043
ENSG00000185088homo_sapiensENSP0000033101988.095285.7143terrapene_carolina_triunguisENSTMTP0000001429978.723476.5957
ENSG00000185088homo_sapiensENSP0000033101992.857184.5238betta_splendensENSBSLP000000209836054.6154
ENSG00000185088homo_sapiensENSP0000033101994.047686.9048anabas_testudineusENSATEP0000005361261.718857.0312
ENSG00000185088homo_sapiensENSP0000033101997.61994.0476ciona_savignyiENSCSAVP0000000899497.61994.0476
ENSG00000185088homo_sapiensENSP0000033101994.047684.5238seriola_lalandi_dorsalisENSSLDP0000003209988.76479.7753
ENSG00000185088homo_sapiensENSP0000033101992.857185.7143labrus_bergyltaENSLBEP0000002250269.026663.7168
ENSG00000185088homo_sapiensENSP0000033101989.285784.5238pundamilia_nyerereiENSPNYP0000001635583.333378.8889
ENSG00000185088homo_sapiensENSP0000033101992.857185.7143mastacembelus_armatusENSMAMP0000001112681.2575
ENSG00000185088homo_sapiensENSP0000033101988.095279.7619stegastes_partitusENSSPAP000000231217467
ENSG00000185088homo_sapiensENSP0000033101989.285779.7619acanthochromis_polyacanthusENSAPOP0000000485580.645272.043
ENSG00000185088homo_sapiensENSP0000033101997.61992.8571aquila_chrysaetos_chrysaetosENSACCP0002000293010095.1219
ENSG00000185088homo_sapiensENSP0000033101989.285778.5714larimichthys_croceaENSLCRP0000503180158.593851.5625
ENSG00000185088homo_sapiensENSP0000033101991.666780.9524takifugu_rubripesENSTRUP0000005283879.381470.1031
ENSG00000185088homo_sapiensENSP0000033101991.666786.9048ficedula_albicollisENSFALP0000002514942.777840.5556
ENSG00000185088homo_sapiensENSP0000033101994.047688.0952hippocampus_comesENSHCOP0000001057874.528369.8113
ENSG00000185088homo_sapiensENSP0000033101997.61989.2857cyprinus_carpio_carpioENSCCRP0000013173758.992853.9568
ENSG00000185088homo_sapiensENSP0000033101994.047689.2857coturnix_japonicaENSCJPP0000501020845.402343.1034
ENSG00000185088homo_sapiensENSP0000033101992.857190.4762coturnix_japonicaENSCJPP0000501741677.227775.2475
ENSG00000185088homo_sapiensENSP0000033101997.61990.4762sinocyclocheilus_grahamiENSSGRP0000004013387.23480.8511
ENSG00000185088homo_sapiensENSP0000033101997.61990.4762sinocyclocheilus_grahamiENSSGRP0000007420564.062559.375
ENSG00000185088homo_sapiensENSP0000033101989.285783.3333maylandia_zebraENSMZEP0000503015483.333377.7778
ENSG00000185088homo_sapiensENSP0000033101995.238184.5238tetraodon_nigroviridisENSTNIP0000001123595.238184.5238
ENSG00000185088homo_sapiensENSP0000033101996.428691.6667paramormyrops_kingsleyaeENSPKIP0000002457070.434866.9565
ENSG00000185088homo_sapiensENSP0000033101994.047686.9048scophthalmus_maximusENSSMAP0000002588894.047686.9048

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0000028involved_in ribosomal small subunit assembly1IBAHomo_sapiens(9606)Process
GO:0003723enables RNA binding2HDA,IBAHomo_sapiens(9606)Function
GO:0003735enables structural constituent of ribosome1IBAHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005634located_in nucleus1IDAHomo_sapiens(9606)Component
GO:0006412involved_in translation1IEAHomo_sapiens(9606)Process
GO:0006919involved_in activation of cysteine-type endopeptidase activity involved in apoptotic process1IDAHomo_sapiens(9606)Process
GO:0006978involved_in DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator1IDAHomo_sapiens(9606)Process
GO:0008494enables translation activator activity1IDAHomo_sapiens(9606)Function
GO:0008656enables cysteine-type endopeptidase activator activity involved in apoptotic process1IDAHomo_sapiens(9606)Function
GO:0022627part_of cytosolic small ribosomal subunit1IBAHomo_sapiens(9606)Component
GO:0031571involved_in mitotic G1 DNA damage checkpoint signaling1IMPHomo_sapiens(9606)Process
GO:0042771involved_in intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator1IDAHomo_sapiens(9606)Process
GO:0045727involved_in positive regulation of translation1IDAHomo_sapiens(9606)Process
GO:0046872enables metal ion binding1IEAHomo_sapiens(9606)Function

Expression