Functions and Diseases

RBP Type Non-canonical_RBPs
Diseases Cancer Disease
Drug N.A.
Main interacting RNAs N.A.
Moonlighting functions TF
Localizations N.A.
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000181449 Gene ID 6657 Accession 11195
Symbol SOX2 Alias ANOP3;MCOPS3 Full Name SRY-box transcription factor 2
Status Confidence Length 2512 bases Strand Plus strand
Position 3 : 181711925 - 181714436 RNA binding domain N.A.
Summary This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT). [provided by RefSeq, Jul 2008]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
28955911 SOX2 suppresses the mobility of urothelial carcinoma by promoting the expression of S100A14. Moon-Sing Lee 2016-09-01 Biochemistry and biophysics reports
34073089 Alternate Roles of Sox Transcription Factors beyond Transcription Initiation. Yuli Zhang 2021-05-31 International journal of molecular sciences
32728033 Functional characterization of SOX2 as an anticancer target. Shizhen Zhang 2020-07-29 Signal transduction and targeted therapy
27145457 SOX2 functions as a molecular rheostat to control the growth, tumorigenicity and drug responses of pancreatic ductal adenocarcinoma cells. L Erin Wuebben 2016-06-07 Oncotarget
34105279 Targeted RNA N6 -Methyladenosine Demethylation Controls Cell Fate Transition in Human Pluripotent Stem Cells. Xuena Chen 2021-06-01 Advanced science (Weinheim, Baden-Wurttemberg, Germany)
32016422 Concurrent binding to DNA and RNA facilitates the pluripotency reprogramming activity of Sox2. Linlin Hou 2020-04-17 Nucleic acids research
34497381 LncRNA NEAT1 controls the lineage fates of BMSCs during skeletal aging by impairing mitochondrial function and pluripotency maintenance. Hengguo Zhang 2022-02-01 Cell death and differentiation
31685551 Developmental Plasticity and Cellular Reprogramming in Caenorhabditis elegans. Joel Rothman 2019-11-01 Genetics
26697072 Long Noncoding RNA Regulation of Pluripotency. Alessandro Rosa 2016-01-01 Stem cells international
19300610 Adult neural stem cells: The promise of the future. Philippe Taupin 2007-12-01 Neuropsychiatric disease and treatment
31814023 The master transcription factor SOX2, mutated in anophthalmia/microphthalmia, is post-transcriptionally regulated by the conserved RNA-binding protein RBM24 in vertebrate eye development. Soma Dash 2020-03-13 Human molecular genetics
32286318 The Sox2 transcription factor binds RNA. E Zachariah Holmes 2020-04-14 Nature communications

Transcripts

Name Transcript ID bp Protein Translation ID
SOX2-201 ENST00000325404 2512 317aa ENSP00000323588

Gene Model

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
29787Lipoprotein(a)6.7780000E-005-
40516Platelet Function Tests2.8747500E-005-
54603Cryptoxanthins2.8650000E-005-
54618Cryptoxanthins4.8010000E-005-
88101Eyebrows2E-3127182965

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000181449homo_sapiensENSP0000038009326.609417.5966homo_sapiensENSP0000032358839.116725.8675
ENSG00000181449homo_sapiensENSP0000029389427.1319.5067homo_sapiensENSP0000032358838.170327.4448
ENSG00000181449homo_sapiensENSP0000035956753.13943.2735homo_sapiensENSP0000032358874.763460.8833
ENSG00000181449homo_sapiensENSP0000039827313.23728.519homo_sapiensENSP0000032358831.861220.5047
ENSG00000181449homo_sapiensENSP0000033021860.869652.1739homo_sapiensENSP0000032358875.078964.3533
ENSG00000181449homo_sapiensENSP0000036614448.188439.8551homo_sapiensENSP0000032358841.955834.7003
ENSG00000181449homo_sapiensENSP0000030192132.216520.8763homo_sapiensENSP0000032358839.432225.552
ENSG00000181449homo_sapiensENSP0000035535457.510745.0644homo_sapiensENSP0000032358842.271333.123
ENSG00000181449homo_sapiensENSP0000029731629.227119.0821homo_sapiensENSP0000032358838.170324.9211
ENSG00000181449homo_sapiensENSP0000035617213.98719.6463homo_sapiensENSP0000032358827.444818.9274
ENSG00000181449homo_sapiensENSP0000034764632.38123.1746homo_sapiensENSP0000032358832.176723.0284
ENSG00000181449homo_sapiensENSP0000026500715.4059.03054homo_sapiensENSP0000032358836.593121.4511
ENSG00000181449homo_sapiensENSP0000037254741.666731.8627homo_sapiensENSP0000032358826.813920.5047
ENSG00000181449homo_sapiensENSP0000034181530.208319.5312homo_sapiensENSP0000032358836.593123.6593
ENSG00000181449homo_sapiensENSP000003407767.116883.63636homo_sapiensENSP0000032358843.217722.082
ENSG00000181449homo_sapiensENSP0000030534357.083347.9167homo_sapiensENSP0000032358843.217736.2776
ENSG00000181449homo_sapiensENSP0000050754511.95657.85024homo_sapiensENSP0000032358831.230320.5047
ENSG00000181449homo_sapiensENSP0000024474523.628717.2996homo_sapiensENSP0000032358835.331225.8675
ENSG00000181449homo_sapiensENSP0000024547925.343816.3065homo_sapiensENSP0000032358840.69426.183
ENSG00000181449homo_sapiensENSP0000032256826.530618.1406homo_sapiensENSP0000032358836.908525.2366

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000181449homo_sapiensENSP00000323588100100nomascus_leucogenysENSNLEP0000002280399.37399.373
ENSG00000181449homo_sapiensENSP0000032358892.744592.7445pan_paniscusENSPPAP0000003667398.327898.3278
ENSG00000181449homo_sapiensENSP00000323588100100pongo_abeliiENSPPYP0000001602799.37399.373
ENSG00000181449homo_sapiensENSP00000323588100100pan_troglodytesENSPTRP0000004675299.37399.373
ENSG00000181449homo_sapiensENSP0000032358894.321891.7981sarcophilus_harrisiiENSSHAP0000003912885.673483.3811
ENSG00000181449homo_sapiensENSP00000323588100100dasypus_novemcinctusENSDNOP0000001543684.759484.7594
ENSG00000181449homo_sapiensENSP0000032358896.845495.2681echinops_telfairiENSETEP0000000516997.151995.5696
ENSG00000181449homo_sapiensENSP0000032358898.738298.1073callithrix_jacchusENSCJAP0000004783698.119197.4922
ENSG00000181449homo_sapiensENSP00000323588100100cercocebus_atysENSCATP0000000488199.37399.373
ENSG00000181449homo_sapiensENSP0000032358886.119986.1199macaca_fascicularisENSMFAP00000013092100100
ENSG00000181449homo_sapiensENSP00000323588100100macaca_nemestrinaENSMNEP0000000580499.37399.373
ENSG00000181449homo_sapiensENSP0000032358898.738298.7382tursiops_truncatusENSTTRP0000000457299.681599.6815
ENSG00000181449homo_sapiensENSP0000032358890.220889.9054vulpes_vulpesENSVVUP0000000900493.159692.8339
ENSG00000181449homo_sapiensENSP0000032358899.369198.4227mus_spretusMGP_SPRETEiJ_P005957598.746197.8056
ENSG00000181449homo_sapiensENSP00000323588100100equus_asinusENSEASP0000505058998.142498.1424
ENSG00000181449homo_sapiensENSP00000323588100100capra_hircusENSCHIP0000000770299.062599.0625
ENSG00000181449homo_sapiensENSP0000032358899.053698.1073loxodonta_africanaENSLAFP0000001765598.742197.7987
ENSG00000181449homo_sapiensENSP00000323588100100panthera_leoENSPLOP0000002462198.753998.7539
ENSG00000181449homo_sapiensENSP0000032358886.119986.1199ailuropoda_melanoleucaENSAMEP00000011594100100
ENSG00000181449homo_sapiensENSP00000323588100100equus_caballusENSECAP0000007925698.753998.7539
ENSG00000181449homo_sapiensENSP00000323588100100panthera_pardusENSPPRP0000002924298.753998.7539
ENSG00000181449homo_sapiensENSP0000032358894.006394.0063marmota_marmota_marmotaENSMMMP0000000339499.665699.6656
ENSG00000181449homo_sapiensENSP00000323588100100balaenoptera_musculusENSBMSP0001000663698.142498.1424
ENSG00000181449homo_sapiensENSP00000323588100100ursus_americanusENSUAMP0000002343998.753998.7539
ENSG00000181449homo_sapiensENSP0000032358882.965382.9653bison_bison_bisonENSBBBP0000000777185.947785.9477
ENSG00000181449homo_sapiensENSP00000323588100100monodon_monocerosENSMMNP0001500096897.538597.5385
ENSG00000181449homo_sapiensENSP0000032358899.684599.6845sus_scrofaENSSSCP0000007564499.059699.0596
ENSG00000181449homo_sapiensENSP00000323588100100microcebus_murinusENSMICP0000005151499.062599.0625
ENSG00000181449homo_sapiensENSP0000032358899.684599.6845octodon_degusENSODEP0000002656599.371199.3711
ENSG00000181449homo_sapiensENSP0000032358892.744592.1136jaculus_jaculusENSJJAP0000000175693.630692.9936
ENSG00000181449homo_sapiensENSP00000323588100100ovis_aries_rambouilletENSOARP0002000733499.062599.0625
ENSG00000181449homo_sapiensENSP0000032358889.905487.0662ursus_maritimusENSUMAP0000000931489.905487.0662
ENSG00000181449homo_sapiensENSP00000323588100100delphinapterus_leucasENSDLEP0000001617297.839597.8395
ENSG00000181449homo_sapiensENSP00000323588100100physeter_catodonENSPCTP0000500563998.142498.1424
ENSG00000181449homo_sapiensENSP0000032358899.369198.4227mus_caroliMGP_CAROLIEiJ_P005731598.746197.8056
ENSG00000181449homo_sapiensENSP0000032358899.369198.4227mus_musculusENSMUSP0000009675598.746197.8056
ENSG00000181449homo_sapiensENSP00000323588100100dipodomys_ordiiENSDORP0000000701798.753998.7539
ENSG00000181449homo_sapiensENSP0000032358898.107396.8454aotus_nancymaaeENSANAP0000000003197.187595.9375
ENSG00000181449homo_sapiensENSP0000032358858.044258.0442vicugna_pacosENSVPAP0000000961597.354597.3545
ENSG00000181449homo_sapiensENSP00000323588100100chlorocebus_sabaeusENSCSAP0000001840299.37399.373
ENSG00000181449homo_sapiensENSP0000032358899.369198.4227mesocricetus_auratusENSMAUP0000001849098.746197.8056
ENSG00000181449homo_sapiensENSP00000323588100100phocoena_sinusENSPSNP0000000239696.646396.6463
ENSG00000181449homo_sapiensENSP0000032358899.369198.4227rattus_norvegicusENSRNOP0000001623698.746197.8056
ENSG00000181449homo_sapiensENSP00000323588100100prolemur_simusENSPSMP0000001637499.062599.0625
ENSG00000181449homo_sapiensENSP0000032358899.369198.4227microtus_ochrogasterENSMOCP0000000822698.746197.8056
ENSG00000181449homo_sapiensENSP0000032358899.369198.4227peromyscus_maniculatus_bairdiiENSPEMP0000001406898.746197.8056
ENSG00000181449homo_sapiensENSP0000032358899.053698.1073cricetulus_griseus_chok1gshdENSCGRP0000100646398.432697.4922
ENSG00000181449homo_sapiensENSP0000032358882.965381.7035myotis_lucifugusENSMLUP0000002128894.604393.1655
ENSG00000181449homo_sapiensENSP0000032358894.006391.4827vombatus_ursinusENSVURP0001001562584.180881.9209
ENSG00000181449homo_sapiensENSP0000032358888.95988.3281neovison_visonENSNVIP0000002112893.069392.4092
ENSG00000181449homo_sapiensENSP0000032358899.053698.7382heterocephalus_glaber_femaleENSHGLP0000004618798.742198.4277
ENSG00000181449homo_sapiensENSP00000323588100100canis_lupus_dingoENSCAFP0002003018898.447298.4472
ENSG00000181449homo_sapiensENSP00000323588100100sciurus_vulgarisENSSVLP0000500673199.062599.0625
ENSG00000181449homo_sapiensENSP0000032358874.763472.8707procavia_capensisENSPCAP0000000340996.341593.9024
ENSG00000181449homo_sapiensENSP0000032358898.422797.1609nannospalax_galiliENSNGAP0000000237598.734297.4684
ENSG00000181449homo_sapiensENSP0000032358899.684599.6845chinchilla_lanigeraENSCLAP0000002585099.371199.3711
ENSG00000181449homo_sapiensENSP00000323588100100catagonus_wagneriENSCWAP0000001453499.062599.0625
ENSG00000181449homo_sapiensENSP0000032358882.965382.9653ictidomys_tridecemlineatusENSSTOP00000009872100100
ENSG00000181449homo_sapiensENSP00000323588100100otolemur_garnettiiENSOGAP0000002239699.37399.373
ENSG00000181449homo_sapiensENSP0000032358898.422797.7918cebus_imitatorENSCCAP0000000496497.596.875
ENSG00000181449homo_sapiensENSP00000323588100100moschus_moschiferusENSMMSP0000000136399.062599.0625
ENSG00000181449homo_sapiensENSP00000323588100100rhinopithecus_roxellanaENSRROP0000000270099.37399.373
ENSG00000181449homo_sapiensENSP0000032358899.369198.4227mus_pahariMGP_PahariEiJ_P006830398.746197.8056
ENSG00000181449homo_sapiensENSP00000323588100100propithecus_coquereliENSPCOP0000000407398.753998.7539
ENSG00000181449homo_sapiensENSP0000032358836.277630.2839caenorhabditis_elegansF40E10.2.254.245345.283
ENSG00000181449homo_sapiensENSP0000032358846.372234.7003caenorhabditis_elegansK08A8.2a.251.943538.8693
ENSG00000181449homo_sapiensENSP0000032358845.741329.0221drosophila_melanogasterFBpp030994721.674113.7519
ENSG00000181449homo_sapiensENSP0000032358851.104141.0095drosophila_melanogasterFBpp030321139.803431.941
ENSG00000181449homo_sapiensENSP0000032358843.217733.4385ciona_intestinalisENSCINP0000003243343.081833.3333
ENSG00000181449homo_sapiensENSP0000032358827.444823.6593eptatretus_burgeriENSEBUP0000001865965.909156.8182
ENSG00000181449homo_sapiensENSP0000032358887.381783.5962callorhinchus_miliiENSCMIP0000003293289.067585.209
ENSG00000181449homo_sapiensENSP0000032358893.059991.1672latimeria_chalumnaeENSLACP0000000740093.650891.746
ENSG00000181449homo_sapiensENSP0000032358892.113688.6435lepisosteus_oculatusENSLOCP0000002145192.698489.2064
ENSG00000181449homo_sapiensENSP0000032358891.482787.0662danio_rerioENSDARP0000009526692.063587.619
ENSG00000181449homo_sapiensENSP0000032358891.167287.0662carassius_auratusENSCARP0000003379991.74687.619
ENSG00000181449homo_sapiensENSP0000032358866.87760.2524astyanax_mexicanusENSAMXP0000002675180.91672.9008
ENSG00000181449homo_sapiensENSP0000032358878.864474.7634ictalurus_punctatusENSIPUP0000003671774.850370.9581
ENSG00000181449homo_sapiensENSP0000032358890.536387.3817esox_luciusENSELUP0000003429491.111187.9365
ENSG00000181449homo_sapiensENSP0000032358891.482787.6972electrophorus_electricusENSEEEP0000002899892.063588.254
ENSG00000181449homo_sapiensENSP0000032358890.220886.4353salmo_salarENSSSAP0000012310390.793686.9841
ENSG00000181449homo_sapiensENSP0000032358888.012682.6498gadus_morhuaENSGMOP0000002126486.64681.3665
ENSG00000181449homo_sapiensENSP0000032358875.078969.4006fundulus_heteroclitusENSFHEP0000002295677.777871.8954
ENSG00000181449homo_sapiensENSP0000032358867.192464.3533poecilia_reticulataENSPREP0000003353286.585482.9268
ENSG00000181449homo_sapiensENSP0000032358887.697283.9117xiphophorus_maculatusENSXMAP0000002017586.335482.6087
ENSG00000181449homo_sapiensENSP0000032358867.507964.0379oryzias_latipesENSORLP0000001464788.065883.5391
ENSG00000181449homo_sapiensENSP0000032358887.697282.6498cyclopterus_lumpusENSCLMP0000503328685.802580.8642
ENSG00000181449homo_sapiensENSP0000032358881.38877.2871oreochromis_niloticusENSONIP0000007643888.356283.9041
ENSG00000181449homo_sapiensENSP0000032358867.507964.0379haplochromis_burtoniENSHBUP0000002375088.429783.8843
ENSG00000181449homo_sapiensENSP0000032358867.507964.0379astatotilapia_callipteraENSACLP0000003835189.166784.5833
ENSG00000181449homo_sapiensENSP0000032358889.274483.9117sparus_aurataENSSAUP0001001525487.888282.6087
ENSG00000181449homo_sapiensENSP0000032358888.643583.9117lates_calcariferENSLCAP0001000520087.267182.6087
ENSG00000181449homo_sapiensENSP0000032358890.220887.0662xenopus_tropicalisENSXETP0000007267591.961488.746
ENSG00000181449homo_sapiensENSP0000032358894.006391.4827sphenodon_punctatusENSSPUP0000001870294.603292.0635
ENSG00000181449homo_sapiensENSP0000032358894.321891.7981crocodylus_porosusENSCPRP0000501508786.918684.593
ENSG00000181449homo_sapiensENSP0000032358891.167287.0662laticauda_laticaudataENSLLTP0000000164486.268782.3881
ENSG00000181449homo_sapiensENSP0000032358890.536386.7508notechis_scutatusENSNSUP0000000576987.767684.0979
ENSG00000181449homo_sapiensENSP0000032358890.851787.0662pseudonaja_textilisENSPTXP0000002532588.615484.9231
ENSG00000181449homo_sapiensENSP0000032358894.952792.1136gallus_gallusENSGALP0001002320689.583386.9048
ENSG00000181449homo_sapiensENSP0000032358894.952792.429meleagris_gallopavoENSMGAP0000002436895.555693.0159
ENSG00000181449homo_sapiensENSP0000032358889.274484.858neolamprologus_brichardiENSNBRP0000002758387.888283.5404
ENSG00000181449homo_sapiensENSP0000032358891.798187.3817naja_najaENSNNAP0000001563688.990884.7095
ENSG00000181449homo_sapiensENSP0000032358894.637292.1136geospiza_fortisENSGFOP0000000730795.238192.6984
ENSG00000181449homo_sapiensENSP0000032358892.744589.5899erpetoichthys_calabaricusENSECRP0000001856993.333390.1587
ENSG00000181449homo_sapiensENSP0000032358868.454363.7224kryptolebias_marmoratusENSKMAP0000000630884.765678.9062
ENSG00000181449homo_sapiensENSP0000032358867.192463.7224amphilophus_citrinellusENSACIP0000003016388.016583.4711
ENSG00000181449homo_sapiensENSP0000032358888.328182.9653dicentrarchus_labraxENSDLAP0000507662680.691675.7925
ENSG00000181449homo_sapiensENSP0000032358888.328182.9653amphiprion_perculaENSAPEP0000002090787.227481.9315
ENSG00000181449homo_sapiensENSP0000032358894.952793.0599pelodiscus_sinensisENSPSIP0000000054595.555693.6508
ENSG00000181449homo_sapiensENSP0000032358894.952793.0599gopherus_evgoodeiENSGEVP0000501035095.555693.6508
ENSG00000181449homo_sapiensENSP0000032358894.637292.1136chelonoidis_abingdoniiENSCABP0000002675095.238192.6984
ENSG00000181449homo_sapiensENSP0000032358866.246162.776seriola_dumeriliENSSDUP0000002271988.235383.6134
ENSG00000181449homo_sapiensENSP0000032358888.012682.9653gasterosteus_aculeatusENSGACP0000000807286.64681.677
ENSG00000181449homo_sapiensENSP0000032358867.823363.7224cynoglossus_semilaevisENSCSEP0000000237183.333378.2946
ENSG00000181449homo_sapiensENSP0000032358888.012683.9117poecilia_formosaENSPFOP0000002069186.64682.6087
ENSG00000181449homo_sapiensENSP0000032358888.328184.2271myripristis_murdjanENSMMDP0000503600086.956582.9193
ENSG00000181449homo_sapiensENSP0000032358867.823363.4069amphiprion_ocellarisENSAOCP0000002425587.755182.0408
ENSG00000181449homo_sapiensENSP0000032358894.952792.7445terrapene_carolina_triunguisENSTMTP0000001387295.555693.3333
ENSG00000181449homo_sapiensENSP0000032358890.851787.6972hucho_huchoENSHHUP0000005667191.428688.254
ENSG00000181449homo_sapiensENSP0000032358890.536386.4353hucho_huchoENSHHUP0000008647391.111186.9841
ENSG00000181449homo_sapiensENSP0000032358864.353356.1514betta_splendensENSBSLP0000000972550.746344.2786
ENSG00000181449homo_sapiensENSP0000032358887.381782.6498betta_splendensENSBSLP0000000838586.024881.3665
ENSG00000181449homo_sapiensENSP0000032358882.018976.9716pygocentrus_nattereriENSPNAP0000001510377.611972.8358
ENSG00000181449homo_sapiensENSP0000032358841.955832.4921ciona_savignyiENSCSAVP0000001544841.43332.0872
ENSG00000181449homo_sapiensENSP0000032358888.643583.9117seriola_lalandi_dorsalisENSSLDP0000002359587.267182.6087
ENSG00000181449homo_sapiensENSP0000032358888.95983.9117labrus_bergyltaENSLBEP0000001946187.577682.6087
ENSG00000181449homo_sapiensENSP0000032358867.507964.0379pundamilia_nyerereiENSPNYP0000001870289.166784.5833
ENSG00000181449homo_sapiensENSP0000032358888.95983.5962mastacembelus_armatusENSMAMP0000001867869.975265.7568
ENSG00000181449homo_sapiensENSP0000032358871.293466.5615stegastes_partitusENSSPAP0000001387481.588476.1733
ENSG00000181449homo_sapiensENSP0000032358890.851787.6972oncorhynchus_tshawytschaENSOTSP0000506510891.428688.254
ENSG00000181449homo_sapiensENSP0000032358888.012682.6498acanthochromis_polyacanthusENSAPOP0000001273886.915981.6199
ENSG00000181449homo_sapiensENSP0000032358868.138864.6688cyprinodon_variegatusENSCVAP0000000171187.804983.3333
ENSG00000181449homo_sapiensENSP0000032358888.643583.9117larimichthys_croceaENSLCRP0000503773487.267182.6087
ENSG00000181449homo_sapiensENSP0000032358888.328183.9117takifugu_rubripesENSTRUP0000001160884.592180.3625
ENSG00000181449homo_sapiensENSP0000032358894.952792.429ficedula_albicollisENSFALP0000003390972.881470.9443
ENSG00000181449homo_sapiensENSP0000032358888.643583.2808hippocampus_comesENSHCOP0000000817285.932780.7339
ENSG00000181449homo_sapiensENSP0000032358891.482787.0662cyprinus_carpio_carpioENSCCRP0000017168692.063587.619
ENSG00000181449homo_sapiensENSP0000032358891.482787.3817cyprinus_carpio_carpioENSCCRP0000011532092.063587.9365
ENSG00000181449homo_sapiensENSP0000032358894.321891.4827coturnix_japonicaENSCJPP0000501743974.009971.7822
ENSG00000181449homo_sapiensENSP0000032358870.662564.9842poecilia_latipinnaENSPLAP0000003117078.873272.5352
ENSG00000181449homo_sapiensENSP0000032358838.485831.5457sinocyclocheilus_grahamiENSSGRP0000009597753.043543.4783
ENSG00000181449homo_sapiensENSP0000032358838.485831.2303sinocyclocheilus_grahamiENSSGRP0000011214752.360542.4893
ENSG00000181449homo_sapiensENSP0000032358867.507964.0379maylandia_zebraENSMZEP0000502084889.166784.5833
ENSG00000181449homo_sapiensENSP0000032358887.697284.2271tetraodon_nigroviridisENSTNIP0000000657986.335482.9193
ENSG00000181449homo_sapiensENSP0000032358891.798187.3817paramormyrops_kingsleyaeENSPKIP0000001518392.38187.9365
ENSG00000181449homo_sapiensENSP0000032358893.059987.6972paramormyrops_kingsleyaeENSPKIP0000003491693.650888.254
ENSG00000181449homo_sapiensENSP0000032358886.750880.1262scleropages_formosusENSSFOP0001504006984.355877.9141
ENSG00000181449homo_sapiensENSP0000032358892.42989.2744leptobrachium_leishanenseENSLLEP0000004734194.212290.9968
ENSG00000181449homo_sapiensENSP0000032358887.381782.9653scophthalmus_maximusENSSMAP0000003154757.588454.6778
ENSG00000181449homo_sapiensENSP0000032358866.561563.0915oryzias_melastigmaENSOMEP0000001037285.772481.3008

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0000122involved_in negative regulation of transcription by RNA polymerase II1ISSHomo_sapiens(9606)Process
GO:0000785part_of chromatin1ISAHomo_sapiens(9606)Component
GO:0000976enables transcription cis-regulatory region binding1IDAHomo_sapiens(9606)Function
GO:0000978enables RNA polymerase II cis-regulatory region sequence-specific DNA binding1IBAHomo_sapiens(9606)Function
GO:0000981enables DNA-binding transcription factor activity, RNA polymerase II-specific2IBA,ISAHomo_sapiens(9606)Function
GO:0001228enables DNA-binding transcription activator activity, RNA polymerase II-specific1IEAHomo_sapiens(9606)Function
GO:0001649involved_in osteoblast differentiation1IDAHomo_sapiens(9606)Process
GO:0001654involved_in eye development1IEPHomo_sapiens(9606)Process
GO:0001714acts_upstream_of_or_within endodermal cell fate specification1IDAHomo_sapiens(9606)Process
GO:0003677enables DNA binding2IDA,NASHomo_sapiens(9606)Function
GO:0003700enables DNA-binding transcription factor activity2IDA,NASHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005634located_in nucleus3IC,IDA,NASHomo_sapiens(9606)Component
GO:0005654located_in nucleoplasm2IDA,TASHomo_sapiens(9606)Component
GO:0005667part_of transcription regulator complex1TASHomo_sapiens(9606)Component
GO:0005737located_in cytoplasm1IDAHomo_sapiens(9606)Component
GO:0005829located_in cytosol1IDAHomo_sapiens(9606)Component
GO:0006325involved_in chromatin organization1NASHomo_sapiens(9606)Process
GO:0006355involved_in regulation of DNA-templated transcription3IBA,IDA,NASHomo_sapiens(9606)Process
GO:0009611involved_in response to wounding1IEPHomo_sapiens(9606)Process
GO:0009653involved_in anatomical structure morphogenesis1IBAHomo_sapiens(9606)Process
GO:0010468involved_in regulation of gene expression1IMPHomo_sapiens(9606)Process
GO:0016607located_in nuclear speck1IEAHomo_sapiens(9606)Component
GO:0021781involved_in glial cell fate commitment1NASHomo_sapiens(9606)Process
GO:0021983involved_in pituitary gland development1IEPHomo_sapiens(9606)Process
GO:0021984involved_in adenohypophysis development1IEAHomo_sapiens(9606)Process
GO:0022409involved_in positive regulation of cell-cell adhesion1IEAHomo_sapiens(9606)Process
GO:0030154involved_in cell differentiation1IBAHomo_sapiens(9606)Process
GO:0030900involved_in forebrain development1IEPHomo_sapiens(9606)Process
GO:0035019involved_in somatic stem cell population maintenance2IDA,IMPHomo_sapiens(9606)Process
GO:0035198enables miRNA binding1IDAHomo_sapiens(9606)Function
GO:0042246involved_in tissue regeneration1IEAHomo_sapiens(9606)Process
GO:0043281involved_in regulation of cysteine-type endopeptidase activity involved in apoptotic process1IDAHomo_sapiens(9606)Process
GO:0043410involved_in positive regulation of MAPK cascade1IDAHomo_sapiens(9606)Process
GO:0043565enables sequence-specific DNA binding1IDAHomo_sapiens(9606)Function
GO:0045597involved_in positive regulation of cell differentiation1IEAHomo_sapiens(9606)Process
GO:0045665involved_in negative regulation of neuron differentiation1ISSHomo_sapiens(9606)Process
GO:0045893involved_in positive regulation of DNA-templated transcription1IDAHomo_sapiens(9606)Process
GO:0045944acts_upstream_of_or_within positive regulation of transcription by RNA polymerase II2IDAHomo_sapiens(9606)Process
GO:0048839involved_in inner ear development1IEPHomo_sapiens(9606)Process
GO:0050680involved_in negative regulation of epithelial cell proliferation1IDAHomo_sapiens(9606)Process
GO:0070848involved_in response to growth factor1IDAHomo_sapiens(9606)Process
GO:0090090involved_in negative regulation of canonical Wnt signaling pathway1IDAHomo_sapiens(9606)Process
GO:0090649involved_in response to oxygen-glucose deprivation1IEAHomo_sapiens(9606)Process
GO:0097150involved_in neuronal stem cell population maintenance1ISSHomo_sapiens(9606)Process
GO:1902807involved_in negative regulation of cell cycle G1/S phase transition1IDAHomo_sapiens(9606)Process
GO:1904520involved_in regulation of myofibroblast cell apoptotic process1IEAHomo_sapiens(9606)Process

Expression