RBPWorld - a comprehensive database of RNA Binding Proteins

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Functions and Diseases

RBP Type	Canonical_RBPs
Diseases	Disease
Drug	N.A.
Main interacting RNAs	N.A.
Moonlighting functions	N.A.
Localizations	Stress granucle
BulkPerturb-seq

Description

Ensembl ID	ENSG00000180921	Gene ID	286077	Accession	24797
Symbol	FAM83H	Alias	AI3;AI3A	Full Name	family with sequence similarity 83 member H
Status	Confidence	Length	14302 bases	Strand	Minus strand
Position	8 : 143723933 - 143738234	RNA binding domain	FAM83
Summary	The protein encoded by this gene plays an important role in the structural development and calcification of tooth enamel. Defects in this gene are a cause of amelogenesis imperfecta type 3 (AI3). [provided by RefSeq, Mar 2010]

RNA binding domains (RBDs)

Protein	Domain	Pfam ID	E-value	Domain number
ENSP00000373565	FAM83	PF07894	2.2e-100	1
ENSP00000499217	FAM83	PF07894	2.8e-100	1

RNA binding proteomes (RBPomes)

Pubmed ID	Full Name	Cell	Author	Time	Doi

Literatures on RNA binding capacity

Pubmed ID	Title	Author	Time	Journal

Transcripts

Name	Transcript ID	bp	Protein	Translation ID
FAM83H-201	ENST00000388913	5632	1179aa	ENSP00000373565
FAM83H-203	ENST00000650760	6131	1380aa	ENSP00000499217
FAM83H-202	ENST00000395103	3611	906aa	ENSP00000378535

Gene Model

Click here to download ENSG00000180921's gene model file

Pathways

Pathway ID	Pathway Name	Source

Phenotypes

ensgID	Trait	pValue	Pubmed ID
27792	Blood Glucose	6.7900000E-005	-

GWAS

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Protein-Protein Interaction (PPI)

Click here to download ENSG00000180921's PPI file

Paralogs

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Orthologs

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Gene Ontology

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0005515	enables protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0005737	located_in cytoplasm	1	IEA	Homo_sapiens(9606)	Component
GO:0007165	involved_in signal transduction	1	IBA	Homo_sapiens(9606)	Process
GO:0019901	enables protein kinase binding	2	IBA,IPI	Homo_sapiens(9606)	Function
GO:0030335	involved_in positive regulation of cell migration	2	IBA,IMP	Homo_sapiens(9606)	Process
GO:0031214	involved_in biomineral tissue development	1	IEA	Homo_sapiens(9606)	Process
GO:0044380	involved_in protein localization to cytoskeleton	2	IBA,IMP	Homo_sapiens(9606)	Process
GO:0045095	colocalizes_with keratin filament	2	IBA,IDA	Homo_sapiens(9606)	Component
GO:0045104	involved_in intermediate filament cytoskeleton organization	2	IBA,IMP	Homo_sapiens(9606)	Process
GO:1990254	enables keratin filament binding	2	IBA,IDA	Homo_sapiens(9606)	Function

Expression