RBPWorld - a comprehensive database of RNA Binding Proteins

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RBP World!

Functions and Diseases

RBP Type	Canonical_RBPs
Diseases	N.A.
Drug	N.A.
Main interacting RNAs	ncRNA
Moonlighting functions	N.A.
Localizations	N.A.
BulkPerturb-seq

Description

Ensembl ID	ENSG00000180113	Gene ID	221400	Accession	21339
Symbol	TDRD6	Alias	TDR2;CT41.2;SPATA36;NY-CO-45;bA446F17.4	Full Name	tudor domain containing 6
Status	Confidence	Length	16445 bases	Strand	Plus strand
Position	6 : 46687875 - 46704319	RNA binding domain	TUDOR
Summary	This gene encodes a tudor domain-containing protein and component of the chromatoid body, a type of ribonucleoprotein granule present in male germ cells. Studies in rodents have demonstrated a role for the encoded protein in spermiogenesis and the nonsense mediated decay (NMD) pathway. This protein is a major autoantigen in human patients with autoimmune polyendocrine syndrome type 1 (APS1). [provided by RefSeq, Oct 2016]

RNA binding domains (RBDs)

Protein	Domain	Pfam ID	E-value	Domain number
ENSP00000346065	TUDOR	PF00567	2.1e-159	1
ENSP00000346065	TUDOR	PF00567	2.1e-159	2
ENSP00000346065	TUDOR	PF00567	2.1e-159	3
ENSP00000346065	TUDOR	PF00567	2.1e-159	4
ENSP00000346065	TUDOR	PF00567	2.1e-159	5
ENSP00000346065	TUDOR	PF00567	2.1e-159	6
ENSP00000346065	TUDOR	PF00567	2.1e-159	7
ENSP00000443299	TUDOR	PF00567	2.1e-157	1
ENSP00000443299	TUDOR	PF00567	2.1e-157	2
ENSP00000443299	TUDOR	PF00567	2.1e-157	3
ENSP00000443299	TUDOR	PF00567	2.1e-157	4
ENSP00000443299	TUDOR	PF00567	2.1e-157	5
ENSP00000443299	TUDOR	PF00567	2.1e-157	6
ENSP00000443299	TUDOR	PF00567	2.1e-157	7

RNA binding proteomes (RBPomes)

Pubmed ID	Full Name	Cell	Author	Time	Doi

Literatures on RNA binding capacity

Pubmed ID	Title	Author	Time	Journal
37013516	Stress decreases spermatozoa quality and induces molecular alterations in zebrafish progeny.	G David Valcarce	2023-04-03	BMC biology
34680140	Bucky Ball Is a Novel Zebrafish Vasa ATPase Activator.	Priyarangana Roshan Perera	2021-10-13	Biomolecules
31892844	The Function of Pre-mRNA Alternative Splicing in Mammal Spermatogenesis.	Huibin Song	2020-01-01	International journal of biological sciences

Transcripts

Name	Transcript ID	bp	Protein	Translation ID

Gene Model

Click here to download ENSG00000180113's gene model file

Pathways

Pathway ID	Pathway Name	Source

Phenotypes

ensgID	Trait	pValue	Pubmed ID
59711	Blood Pressure	1.9076735E-005	-
60084	Arterial Pressure	2.1762496E-005	-

GWAS

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Protein-Protein Interaction (PPI)

Click here to download ENSG00000180113's PPI file

Paralogs

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Orthologs

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Gene Ontology

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0005737	located_in cytoplasm	1	ISS	Homo_sapiens(9606)	Component
GO:0007283	involved_in spermatogenesis	2	IBA,ISS	Homo_sapiens(9606)	Process
GO:0030719	involved_in P granule organization	1	IBA	Homo_sapiens(9606)	Process
GO:0033391	located_in chromatoid body	1	ISS	Homo_sapiens(9606)	Component
GO:0034587	involved_in piRNA processing	1	IBA	Homo_sapiens(9606)	Process
GO:0043186	is_active_in P granule	1	IBA	Homo_sapiens(9606)	Component

Expression